Detergents, Cosmetics, Disinfectants, Pharma Chemicals

DIPENTENE
Dipentene
CAS Number: 138-86-3
Molecular Weight: 136.23752000
Molecular Formula: C10H16



APPLICATIONS


Benefits of Dipentene:

A special pleasant aroma
A cyclic Terpene
Disolve anhydrous ethanol, ether, chloroform and other organic solvents and insoluble in water


Dipentene was employed as a solvent in the reaction media for enzymatic synthesis of phosphatidylserine.


Identified uses of Dipentene:

Laboratory chemicals
Manufacture of substances


Dipentene is used as a solvent for resins, alkyds and waxes and to make paints, enamels, lacquers and polishes.
Furthermore, Dipentene is used as a perfumery composition for soaps, personal care products and cosmetics.
Dipentene is used as an intermediate for terpene resins, carvone, terylene, and rubber chemicals. It is used as an oils dispersant, metal dryer.

Dipentene is used as a substitute for chlorinated solvents in degreasing metals for cleaning in the electronic industry.
Moreover, Dipentene is used as starting material for the synthesis of terpene resin.
Dipentene is used as a gallstone solubilizer in pharmaceutical industry.


Applications of Dipentene:

Products used for cleaning or safety in an occupational or industrial setting (e.g. industrial cleaning supplies or laundry detergent, eye wash, spill kits)
Cleaning and household care products that can not be placed in a more refined category
Home air fresheners, including candles with a fragrance
Bathtub, tile, and toilet surface cleaners
Carpet-cleaning products that may be used directly (or require dilution), includes solutions that may be used by hand or in mechanical carpet cleaners
Hard floor cleaners, including pre-moistened wipes
Products that impart a shine to solid floors
Detergent based products used during the hand washing of dishes
Cleaning products for general household cleaning, which do not fit into a more refined category
Products used to control microbial pests on hard surfaces or laundry
Products used to clean glass, mirrors, and windows
Products used to clean hard surfaces in the home, including kitchen specific hard surface cleaners
Heavy duty hard surface cleaning products that may require dilution prior to use (i.e., may be concentrated)
Products used in washing machines to clean fabrics
Products used to clean grills, ovens, or range cooktops
Products applied to footwear to color, polish, clean, or add a protective surface
flavouring
fragrance
Products for removing grease and other hydrophobic materials from hard surfaces
Paint or stain related products that do not fit into a more refined category
Products used on wooden surfaces, including decks, to impart transparent or semitransparent color
Products for coating and protecting household surfaces other than glass, stone, or grout
General personal care products which do not fit into a more refined category
Facial cleansing products (excluding scrubs), for acne treatment
Multicomponent body care or bath set for which individual products are not designated
Products related to body hygiene which do not fit into a more refined category
Bar and other solid soaps
Body cleaners containing abrasives or exfoliants
Body cleaners, washes, shower gels
Antibacterial products for application to hands
Liquid hand soaps
Lipophilic products applied to skin (excluding baby oils)
Personal care products intended for use by children, which do not fit into a more specific category
Toothpastes and dentrifices
Deodorants and antiperspirants
Facial cleansing and moisturizing products which do not fit into a more refined category
Moisturizers, lotions, and creams for treating the face (excluding eye-specific products)
Leave-on masks or peels for treatment of the face
Miscellaneous products for application to feet, including scrubs, lotions, deodorants, and treatments for skin and nail problems
Fragrances, colognes, and perfumes
General moisturizing products which do not fit into a more refined category
Products specifically marketed for application to hands or body to moisturize or improve skin characteristics (excluding baby lotion)
General hair styling or hair care products which do not fit into a more refined category
Products for removing oil and dirt from hair
Rinse-out everyday hair conditioners (excluding combo shampoo/conditioner products)
Leave-in everyday hair conditioners and detanglers
Spray fixatives for hair


Dipentene is used in products for imparting hold, shine, or texture to hair.
Besides, Dipentene is used in shampoos, including dual shampoo/conditioner products.
Dipentene is used in make-up or cosmetic products which do not fit into a more refined category.

Dipentene is used in eye liners or brow coloring products.
In addition, Dipentene is used in foundation make-up and concealers.

Dipentene is used in lip products primarily for protection.
Additionally, Dipentene is used in colored lip products, excluding glosses.

Dipentene is used in adhesives for reparing fingernails or attaching artificial nails.
More to that, Dipentene is used in chemical products for tanning, staining, or coloring the skin.

Dipentene is used in products applied to the skin following shaving to provide scent, or improve skin characteristics.
Further to that, Dipentene is used in cleaning and lubricating products for hair clippers.
Dipentene is used in shaving creams, foams, balms and soaps.

Dipentene is used in solid or powdered products added to bathwater including bath salts, soaks, and fizzes.
Furthermore, Dipentene is used in products added to bath water to create bubbles, may provide cleaning, fragrance, or improve skin characteristics (including bubble bath marketed to babies or children).

Dipentene is used in products applied to the skin to block harmful effects of sunlight.
Moreover, Dipentene is used in products for repelling insects from skin.
Dipentene is used in insecticides, for interior or exterior use.

Dipentene is used in products for masking odors or adding fragrance to car cabin air.
Besides, Dipentene is used in auto body waxes and coatings, excluding combo wash/wax products.

Dipentene is used in flavorings, fragrances, cosmetics and as a solvent and wetting agent.
Also, Dipentene is used to make resins, insecticides, insect repellants, and animal repellants.

Dipentene is used as a dissolving agent for gallstones and gutta-percha.
In addition, Dipentene is used in floor waxes and furniture polishes.
Dipentene occurs naturally in essential oils of many plants and is a minor constituent of turpentine.

Dipentene is monomer in terpene resins; solvent for oleoresinous products; general wetting and dispersing agent; chemical intermediate for various organic compounds; flavor ingredient (orange-like).
One important use for Dipentene is its use as a chiral starting material for the synthesis of (R)-(-)-carvone.

An application for printed circuit board cleaners has also been developed using dipentene and limonene with emulsifying surfactants to facilitate removal by rinsing in water.


Industry Uses of Dipentene:

Adhesion/cohesion promoter
Fragrance
Fuels and fuel additives
Intermediates
Monomers
Odor agents


Consumer Uses:

Fragrance
Fuels and fuel additives
Odor agents


Dipentene is common as a dietary supplement and as a fragrance ingredient for cosmetics products.
As the main fragrance of citrus peels, Dipentene is used in food manufacturing and some medicines, such as a flavoring to mask the bitter taste of alkaloids, and as a fragrance in perfumery, aftershave lotions, bath products, and other personal care products.
Dipentene is also used as a botanical insecticide.

Additionally, Dipentene is used in the organic herbicides.
Dipentene is added to cleaning products, such as hand cleansers to give a lemon or orange fragrance (see orange oil) and for its ability to dissolve oils.
In contrast, Dipentene has a piny, turpentine-like odor.

Dipentene is used as a solvent for cleaning purposes, such as adhesive remover, or the removal of oil from machine parts, as it is produced from a renewable source (citrus essential oil, as a byproduct of orange juice manufacture).
More to that, Dipentene is used as a paint stripper and is also useful as a fragrant alternative to turpentine.

Dipentene is also used as a solvent in some model airplane glues and as a constituent in some paints.
Commercial air fresheners, with air propellants, containing Dipentene are used by stamp collectors to remove self-adhesive postage stamps from envelope paper.

Dipentene is also used as a solvent for fused filament fabrication based 3D printing.
Printers can print the plastic of choice for the model, but erect supports and binders from High Impact Polystyrene (HIPS), a polystyrene plastic that is easily soluble in Dipentene.

In preparing tissues for histology or histopathology, Dipentene is often used as a less toxic substitute for xylene when clearing dehydrated specimens.
Clearing agents are liquids miscible with alcohols (such as ethanol or isopropanol) and with melted paraffin wax, in which specimens are embedded to facilitate cutting of thin sections for microscopy.

Dipentene is also combustible and has been considered as a biofuel.
With its pine, lime like aroma, Dipentene is considered refreshing in flavours and fragrances.
Dipentene delivers herbal, citrus, aromatic, flavours that hold hints of pine, mint, and wood and are often described as being tropical.


Dipentene has excellent perfumery and flavouring properties, and is often used in:

Cosmetics
Soap, a variety of toiletries, and air freshener
Hair colour
Household cleaning products
Nappies
Food flavourant


From an industrial perspective, Dipentene’s effective solvent properties make it ideal for applications in:

Resins, alkyds, enamels, lacquers, paints, and varnish
Rubber processing and reclaiming
Industrial cleaning and deodorising products including waxes and polishes, offering germicidal, fungicidal, and insecticidal properties
Deoderisers, re-odorants, and masking agents
Oil extraction
Degreaser (particularly for metals) and defoamer
Pesticides
Some applications in the pharmaceutical sector



DESCRIPTION


Dipentene (Limonene) is a monoterpene olefin having potential applications in polymer and fuel chemistry.
Further to that, Dipentene is also widely used as flavoring and fragrance agent.
Dipentene (limonene) is a promising green solvent.

Kinetics of the reactions of Dipentene with OH and OD radicals has been investigated in a low pressure flow tube reactor coupled with a quadrupole mass spectrometer.

Dipentene (also called D-Limonene), is a terpene liquid found in various volatile oils such as cardamon, mace, nutmeg , turpentine oil.
Furthermore, Dipentene is mainly composed of Limonene, beta-Phellandrene, Myrcene and other terpenes.

Dipentene is a colorless liquid aliphatic hydrocarbon classified as a cyclic monoterpene, and is the major component in the oil of citrus fruit peels.
The d-isomer, occurring more commonly in nature as the fragrance of oranges, is a flavoring agent in food manufacturing.
Dipentene is also used in chemical synthesis as a precursor to carvone and as a renewables-based solvent in cleaning products.

The less common l-isomer has a piny, turpentine-like odor, and is found in the edible parts of such plants as caraway, dill, and bergamot orange plants.

Dipentene is a relatively stable monoterpene and can be distilled without decomposition, although at elevated temperatures it cracks to form isoprene.
Moreover, Dipentene oxidizes easily in moist air to produce carveol, carvone, and limonene oxide.
With sulfur, Dipentene undergoes dehydrogenation to p-cymene.

Dipentene occurs commonly as the (R)-enantiomer, but racemizes to dipentene at 300 °C.
When warmed with mineral acid, Dipentene isomerizes to the conjugated diene α-terpinene (which can also easily be converted to p-cymene).
Evidence for this isomerization includes the formation of Diels–Alder adducts between α-terpinene adducts and maleic anhydride.

Dipentene is possible to effect reaction at one of the double bonds selectively.
Anhydrous hydrogen chloride reacts preferentially at the disubstituted alkene, whereas epoxidation with mCPBA occurs at the trisubstituted alkene.
In another synthetic method Markovnikov addition of trifluoroacetic acid followed by hydrolysis of the acetate gives terpineol.



PROPERTIES


Appearance Form: liquid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: -89 °C
Initial boiling point and boiling range: 170 - 180 °C - lit.
Flash point: 43 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 6,1 %(V)
Lower explosion limit: 0,7 %(V)
Vapor pressure: 1 hPa at 20 °C
Vapor density: 4,7 - (Air = 1.0)
Density: 0,86 g/mL at 20 °C - lit.
Relative density: No data available
Water solubility at 20 °C: insoluble
Partition coefficient (n-octanol/water): log Pow: 4,57
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Molecular Weight: 136.23
XLogP3-AA: 13.4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 0
Rotatable Bond Count: 1
Exact Mass: 136.125200510
Monoisotopic Mass: 136.125200510
Topological Polar Surface Area: 0 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 163
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID


Description of first-aid measures:

General advice:

Consult a physician.
Show this material safety data sheet to the doctor in attendance.


If inhaled:

If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.


In case of skin contact:

Wash off with soap and plenty of water.
Consult a physician.


In case of eye contact:

Flush eyes with water as a precaution.


If swallowed:

Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.


Most important symptoms and effects, both acute and delayed:

The most important known symptoms and effects are described in the labelling.


Indication of any immediate medical attention and special treatment needed:

No data available



HANDLING AND STORAGE


Precautions for safe handling:

Advice on safe handling:

Avoid contact with skin and eyes.
Avoid inhalation of vapor or mist.


Advice on protection against fire and explosion:

Keep away from sources of ignition - No smoking.
Take measures to prevent the build up of electrostatic charge.


Hygiene measures:

Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.


Conditions for safe storage, including any incompatibilities:

Storage conditions:

Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Store in cool place.


Storage class:

Storage class (TRGS 510): 3: Flammable liquids


Specific end use(s):

Apart from the uses mentioned above, no other specific uses are stipulated.


Storage:

Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Keep container tightly closed in a dry and well-ventilated place.
Store in cool place.



SYNONYMS


DIPENTENE ( D-LIMONENE / CITRUS & PINUS )
1-methyl-4-(1-methylethenyl)cyclohexene
Cajeputene
Cinene
Ciene
p-Menthdecene
limonene
p-mentha-1,8-diene
4-isopropenyl-1-methyl-Cyclohexene
Dipenten
DL-p-mentha-1,8-diene
4-Isopropenycyclohexene; Mentha-1,8-diene
Mentha-1,8-diene, DL
Menthadiene
Methyl-4-(1-methylethenyl)cyclohexene
Methyl-4-isoprocyclohexene
Methyl-4-isopropenylcyclohexene
Monocyclic terpene hydrocarbons
Terpodiene
4-(1-methylethenyl)-1-methylNO:138-86-3
LIMONENE
Dipentene
138-86-3
Cinene
Cajeputene
Kautschin
DL-Limonene
Dipenten
Eulimen
Nesol
p-Mentha-1,8-diene
1,8-p-Menthadiene
Cyclohexene, 1-methyl-4-(1-methylethenyl)-
Cajeputen
Limonen
Cinen
1-Methyl-4-(1-methylethenyl)cyclohexene
Inactive limonene
Acintene DP dipentene
Polylimonene
Dipanol
Unitene
alpha-Limonene
Flavor orange
Orange flavor
Goldflush II
(+/-)-Limonene
Acintene DP
4-Isopropenyl-1-methyl-1-cyclohexene
4-Isopropenyl-1-methylcyclohexene
Di-p-mentha-1,8-diene
1,8(9)-p-Menthadiene
DL-4-Isopropenyl-1-methylcyclohexene
Limonene, dl-
1-methyl-4-prop-1-en-2-ylcyclohexene
p-Mentha-1,8-diene, dl-
1-Methyl-4-isopropenyl-1-cyclohexene
1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene
7705-14-8
MENTHA-1,8-DIENE (DL)
Dipentene, technical grade
.alpha.-Limonene
NSC 21446
PC 560
Limonene, (+/-)-
.delta.-1,8-Terpodiene
Terpenes and Terpenoids, limonene fraction
CHEBI:15384
1-Methyl-4-isopropenylcyclohexene
NSC-844
NSC-21446
9MC3I34447
65996-98-7
NCGC00163742-03
Polydipentene
Limonene polymer
DSSTox_CID_9612
d,l-Limonene
Dipentene polymer
DSSTox_RID_78787
DSSTox_GSID_29612
Dipentene 200
(+-)-Dipentene
Orange x
(+-)-Linonene
Caswell No. 526
Cyclohexene, 1-methyl-4-(1-methylethenyl)-, (.+/-.)-
delta-1,8-Terpodiene
(+-)-alpha-Limonene
Dipentene, crude
CAS-138-86-3
HSDB 1809
NSC 844
p-Mentha-1,8-diene, (+-)-
Cyclohexene, 1-methyl-4-(1-methylethenyl)-, (R)-
EINECS 205-341-0
EINECS 231-732-0
UN2052
1-Methyl-p-isopropenyl-1-cyclohexene
DIPENTENE (+-)
EPA Pesticide Chemical Code 079701
Terpodiene
Ciene
Cyclil decene
AI3-00739
UNII-9MC3I34447
Achilles dipentene
Dipentene, tech.
4-isopropenyl-1-methyl-cyclohexene
Dipentene, technical, for use as solvent (for the paint industry), mixture of various terpenes
c0626
Mentha-1,8-diene
p-Mentha-1, dl-
Dipentene, homopolymer
d(R)-4-Isopropenyl-1-methylcyclohexene
(.+-.)-Limonene
(.+-.)-Dipentene
LIMONENE [HSDB]
LIMONENE [MI]
(.+/-.)-Dipentene
(.+/-.)-Limonene
DIPENTENE 38 PF
DIPENTENE [VANDF]
ESSENCE DE PIN PF
(1)-1-Methyl-4-(1-methylvinyl)cyclohexene
DL-p-mentha-1,8-diene
Mentha-1,8-diene, DL
(+-)-(RS)-limonene
DIPENTEN [WHO-DD]
Cyclohexene, (.+-.)-
Dipentene, p.a., 95%
p-Mentha-1,8(9)-diene
Dipentene, mixture of isomers
CHEMBL15799
Monocyclic terpene hydrocarbons
Methyl-4-isopropenylcyclohexene
NSC844
(.+/-.)-.alpha.-Limonene
DTXSID2029612
(+/-)-p-Mentha-1,8-diene
p-Mentha-1, (.+-.)-
HMS3264E05
Pharmakon1600-00307080
Methyl-4-isopropenyl-1-cyclohexene
HY-N0544
NSC21446
Tox21_112068
Tox21_201818
Tox21_303409
MFCD00062992
NSC757069
STK801934
1-methyl-4-isopropenylcyclohex-1-ene
LIMONENE, (+/-)- [II]
AKOS009031280
Cyclohexene, 4-Isopropenyl-1-methyl-
Methyl-4-(1-methylethenyl)cyclohexene
WLN: L6UTJ A1 DY1 & U1
CCG-214016
p-Mentha-1,8-diene, (.+/-.)-
p-Mentha-1,8-diene, polymers (8CI)
SB44847
UN 2052
(+/-)-p-Mentha-1,8-diene homopolymer
Limonene 1000 microg/mL in Isopropanol
NCGC00163742-01
NCGC00163742-02
NCGC00163742-04
NCGC00163742-05
NCGC00257291-01
NCGC00259367-01
Terpenes andTerpenoids, limonene fraction
8016-20-4
8050-32-6
NCI60_041856
p-Mentha-1,8-diene, homopolymer (7CI)
1-methyl-4-(1-methylethenyl) cylcohexene
1-methyl-4-(prop-1-en-2-yl)cyclohexene
4-(1-methylethenyl)-1-methyl-cyclohexene
Dipentene [UN2052] [Flammable liquid]
Cyclohexene, 1-methyl-4-(1-methylethynyl)
DB-053490
DB-072716
CS-0009072
FT-0600409
FT-0603053
FT-0605227
L0046
EN300-21627
C06078
D00194
E88572
1-METHYL-4-PROP-1-EN-2-YL-CYCLOHEXENE
AB01563249_01
Q278809
SR-01000872759
J-007186
J-520048
SR-01000872759-1
TERPIN MONOHYDRATE IMPURITY C [EP IMPURITY]
(+/-)-1-METHYL-4-(1-METHYLETHENYL)CYCLOHEXENE
4B4F06FC-8293-455D-8FD5-C970CDB001EE
Dipentene, mixt. of limonene, 56-64%, and terpinolene, 20-25%
555-08-8
8022-90-0
DIPEPTIDE-2
Ses fonctions (INCI) Agent d'entretien de la peau : Maintient la peau en bon état
DIPEPTIDE-4
DIPHENYL ETHER, N° CAS : 101-84-8. Nom INCI : DIPHENYL ETHER. Nom chimique : Benzene, 1,1'-Oxybis. N° EINECS/ELINCS : 202-981-2. Ses fonctions (INCI) : Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit
DIPHENYL CARBONATE
Diphenyl carbonate is a carbonate ester of formula (C6H5O)2CO, which is mostly used as a critical comonomer in the manufacture of polycarbonate resin, an engineering thermoplastic with high impact resistance and excellent optical properties.
Diphenyl carbonate is produced from phenol and carbonyl dichloride using a new nitrogen containing catalyst without the use of organic solvent.
Diphenyl carbonate is commonly produced by indirect methods, mainly by transesterification of dialkylcarbonates such as dimethyl carbonate produced either from CO, methanol, and oxygen using EniChem technology (SABIC IP) or via carbonylation of methyl nitrite from the reaction of NO with methanol or by methanolysis of ethylene carbonate or di-n-butyl carbonate from urea and n-butyl alcohol.

CAS Number: 102-09-0
EC Number: 203-005-8
Molecular Weight: 214.22
Molecular Formula: C13H10O3

Synonyms: DIPHENYL CARBONATE, 102-09-0, Carbonic acid, diphenyl ester, Diphenylcarbonate, Phenyl carbonate, Phenyl carbonate ((PhO)2CO), UNII-YWV401IDYN, Carbonic Acid Diphenyl Ester, Ph2CO3, (PhO)2CO, YWV401IDYN, CHEBI:34722, NSC 37087; Phenyl carbonate, MFCD00003037, HSDB 5346, EINECS 203-005-8, NSC 37087, BRN 1074863, phenoxy ketone, AI3-00063, Phenol carbonate, diphenyl-carbonate, Carbonic acid diphenyl, WLN: ROVOR, DSSTox_CID_540, EC 203-005-8, Cambridge id 6944698, DSSTox_RID_75649, DSSTox_GSID_20540, SCHEMBL18073, BIDD:ER0260, CHEMBL3188080, DTXSID3020540, ZINC134817, NSC37087, Tox21_200150, NSC-37087, STL185617, AKOS002275760, MCULE-5577922375, NCGC00248543-01, NCGC00257704-01, BS-14177, CAS-102-09-0, Diphenyl carbonate, ReagentPlus(R), 99%, FT-0625229, EN300-36556, A800511, Diphenyl carbonate 100 microg/mL in Acetonitrile, Diphenyl carbonate, Vetec(TM) reagent grade, 98%, Q413098, SR-01000246916, Q-201005, SR-01000246916-1, Z28228668, F3096-1220, 102-09-0 [RN], 203-005-8 [EINECS], Carbonate de diphényle, Carbonic acid diphenyl ester, Carbonic acid, diphenyl ester, Diphenyl carbonate, Diphenylcarbonat, Diphenylcarbonate, MFCD00003037, Phenyl carbonate, UNII-YWV401IDYN, YWV401IDYN, 203-005-8MFCD00003037, 2-HYDROXYIMINO-2-(2-PYRIDYLSULFONYL)ACETONITRILE, 4-06-00-00629, Phenol carbonate, phenyl phenoxyformate, ROVOR, UNII:YWV401IDYN

Diphenyl carbonate is the organic compound with the formula (C6H5O)2CO.
Diphenyl carbonate is classified as an acyclic carbonate ester.

Diphenyl carbonate is a colorless solid.
Diphenyl carbonate is both a monomer in combination with bisphenol A in the production of polycarbonate polymers and a product of the decomposition of polycarbonates.

Diphenyl carbonate is an essential and nontoxic precursor for the polycarbonate (PC) production.
With the development of carbonate industry, the need for Diphenyl carbonate will be increasing.

Kim and Lee (1999) suggested a transesterification way of dimethyl carbonate (DMC) and phenol to manufacture Diphenyl carbonate.
However, the equilibrium constant for transesterifications of DMC and phenol was only 3 × 10− 4 at 180 °C in the research of Tundo and Selva (2002).

To overcome this problem, diethyl carbonate (DEC) and phenyl ester (PA) transesterification to produce the product Diphenyl carbonate and the byproduct ethyl acetate (EtAc) was proposed.
The advantages of this process include higher equilibrium constant and no azeotropes.

Diphenyl carbonate is produced from phenol and carbonyl dichloride using a new nitrogen containing catalyst without the use of organic solvent.
Transesterification of Diphenyl carbonate and bisphenol-A to produce PC is performed in the presence of an alkali metal compound catalyst controlling the amount of branching structures and the polymer molecular weight based on the kinetics.
The first commercial plant based on this process started in 2000.

Diphenyl carbonate is a carbonate ester of formula (C6H5O)2CO, which is mostly used as a critical comonomer in the manufacture of polycarbonate resin, an engineering thermoplastic with high impact resistance and excellent optical properties.
Originally, polycarbonate was produced by interfacial (organic/aqueous) polycondensation of phosgene (COCl2) with disodium salt of a bisphenol, such as 2,2-bis(4-hydroxyphenyl)propane (bisphenol A).
However, a phosgene-free route was desired because of environmental hazards and governmental restrictions associated with production and storage of extremely toxic phosgene (and chlorine used to synthesize Diphenyl carbonate) and the use of chlorinated solvents.

Diphenyl carbonate is commonly produced by indirect methods, mainly by transesterification of dialkylcarbonates such as dimethyl carbonate produced either from CO, methanol, and oxygen using EniChem technology (SABIC IP) or via carbonylation of methyl nitrite from the reaction of NO with methanol or by methanolysis of ethylene carbonate or di-n-butyl carbonate from urea and n-butyl alcohol.
Ideally, Diphenyl carbonate can be prepared directly from phenol, carbon monoxide, and oxygen in a simpler (one-step) energetically favorable reaction.
Development of the one-step Diphenyl carbonate synthesis process conducted by GE team and other researchers, which resulted in tremendous increase in catalytic activity from tens to greater than 10 000 Pd turnover numbers and eventually in a viable technology process, is described.

Diphenyl carbonate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.
Diphenyl carbonate is used at industrial sites and in manufacturing.

Diphenyl carbonate is an acyclic carbonate ester.
Diphenyl carbonate is both as a monomer in combination with bisphenol A in the production of polycarbonate polymers and a product of the decomposition of polycarbonates.

Diphenyl carbonate is a phenol that is used as a precursor to other chemicals.
Diphenyl carbonate is produced through the oxidation of benzene with phosphorus oxychloride, and is also obtained by the chlorination of phenol.

In electrochemical impedance spectroscopy, Diphenyl carbonate has been shown to be an effective model system for multi-walled carbon nanotubes.
The optimum concentration of diphenyl carbonate in the reaction solution was determined using analytical methods and reactive properties were observed in a solid catalyst system.

The mechanism for this reaction is unknown.
Diphenyl carbonate has been shown to react with dibutyltin oxide in the presence of hydroxyl groups to form diphenyl compounds, which are catalysts for various organic reactions.

Diphenyl carbonate was synthesized from phenol and dense phase CO2 in the presence of CCl4 and K2CO3 using different catalysts of ZnCl2, ZnBr2, Lewis acid ionic liquids including 1-butyl-3-methylimidazolium chloride (BMIMCl) and bromide (BMIMBr).
Diphenyl carbonate was found that K2CO3 was not required, ZnCl2 and ZnBr2 were similar in the catalytic performance, and the use of BMIMCl and BMIMBr was not effective for the production of Diphenyl carbonate.

For the reactions with ZnCl2 in CCl4, the effects of such reaction variables as temperature, CO2 pressure, the amount of ZnCl2, and the volume of CCl4 were studied in detail.
Diphenyl carbonate was shown that the pressure was less influential while a larger amount of ZnCl2, a smaller volume of CCl4, and a low temperature of around 100°C were beneficial for the synthesis of Diphenyl carbonate.
On the basis of the results obtained, possible reaction mechanisms were discussed.

Uses of Diphenyl carbonate:
Diphenyl carbonate is used in the synthesis of polycarbonate resins
As a reagent for the conversion of amines into isocyanates
As a plasticizer and solvent; as a solvent for nitrocellulose (in molten state).

In molten state as solvent for nitrocellulose

Plasticizer & solvent
Synthesis of polycarbonate resins

Diphenyl carbonate is used in place of carbon monoxide, as reagents for the conversion of amines into isocyanates.

Uses at industrial sites of Diphenyl carbonate:
Diphenyl carbonate is used in the following products: polymers.
Diphenyl carbonate has an industrial use resulting in manufacture of another substance (use of intermediates).

Diphenyl carbonate is used for the manufacture of: chemicals and plastic products.
Release to the environment of Diphenyl carbonate can occur from industrial use: for thermoplastic manufacture.

Applications of Diphenyl carbonate:
Polycarbonates can be prepared by transesterifying diphenyl carbonate with bisphenol A.
Phenol is a co-product.
These polycarbonates may be recycled by reversing the process: transesterifying the polycarbonate with phenol to yield diphenyl carbonate and bisphenol A.

D 2320 (OTTO) Diphenyl carbonate, 99% Cas 102-09-0 - used for the production of polycarbonates using.
D 2320 (OTTO) Diphenyl carbonate, 99% Cas 102-09-0 - used for synthesis of many important organic compounds.
As agrochemical intermediates, Dyestuff intermediate.

Benefits of Diphenyl carbonate:
High Diphenyl carbonate product purity, suitable for high quality polycarbonate production
No use of chlorinated compounds, environmentally safe, no corrosion
High phenol conversion per pass, low recycle flows
Commercially available catalyst
Can be designed for high capacities
Extensive heat integration, low energy consumption
Low investment cost

Production of Diphenyl carbonate:
World production capacity of diphenyl carbonate was 254,000 tonnes in 2002, and phosgenation of phenol is the most significant route.
Phosgenation of phenol can proceed under various conditions.

The net reaction is as follows:
2 PhOH + COCl2 → PhOCO2Ph + 2 HCl

The use of phosgene can be avoided by the oxidative carbonylation of phenol with carbon monoxide:
2 PhOH + CO + [O] → PhOCO2Ph + H2O

Dimethyl carbonate can also be transesterified with phenol:
CH3OCO2CH3 + 2 PhOH → PhOCO2Ph + 2 MeOH

The kinetics and thermodynamics of this reaction are not favorable.
For example, at higher temperatures, dimethyl carbonate undesirably methylates phenol to give anisole.
Despite this, diphenyl carbonate made from non-phosgene sources has become a widely used raw material for the synthesis of bisphenol-A-polycarbonate in a melt polycondensation process.

Manufacture of Diphenyl carbonate:
Release to the environment of Diphenyl carbonate can occur from industrial use: manufacturing of Diphenyl carbonate.

Handling And Storage of Diphenyl carbonate:

Handling of Diphenyl carbonate:

Technical measures:
Avoid contact with strong oxidizing agents.
Use with local exhaust ventilation.

Precautions:
Do not rough handling containers, such as upsetting, falling, giving a shock, and dragging.
Prevent leakage, overflow, andscattering.

Not to generate steam and dust in vain.
Seal the container after use.

After handling, wash hands andface, andthen gargle.
In places other than those specified, should not be smoking or eating and drinking.

Should not bebrought:
contaminated protective equipment and gloves to rest stops.
Deny unnecessary entry of non-emergency personnel tothehandling area.

Safety handling precautions:
Avoid contact with skin, eyes or clothing.
Use personal protective equipment as required.

Storage of Diphenyl carbonate:

Safe storage conditions of Diphenyl carbonate:
Store away from sunlight in well-ventilated place at room temperature (preferablycool).
Keep container tightly closed.

Safe packaging material Incompatible substances:
Glass
Strong oxidizing agents

Ecological Information of Diphenyl carbonate:

Environmental Fate/Exposure Summary:
Diphenyl carbonate's production and use as a solvent for nitrocellulose may result in Diphenyl carbonate release to the environment through various waste streams.
If released to air, an estimated vapor pressure of 4X10-4 mm Hg at 25 °C indicates diphenyl carbonate will exist solely as a vapor.

Vapor-phase diphenyl carbonate will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 96 hours.
Diphenyl carbonate may also undergo direct photolysis in the environment since this compound contains a functional group that can absorb light greater than 290 nm.

If released to soil, diphenyl carbonate is expected to be slightly mobile based upon an estimated Koc of 3,900.
Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 8.5X10-5 atm-cu m/mole; however, this process is expected to be attenuated by adsorption.

If released into water, diphenyl carbonate is expected to adsorb to suspended solids and sediment based upon Diphenyl carbonate Koc.
Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant.

Estimated volatilization half-lives for a model river and model lake are 10 days and 12 hours, respectively.
However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column.

The estimated volatilization half-life from a model pond is 126 days if adsorption is considered.
Diphenyl carbonate is expected to undergo hydrolysis due to the presence of hydrolyzable functional groups.

An estimated BCF of 67 suggests the potential for bioconcentration in aquatic organisms is moderate.
Occupational exposure to diphenyl carbonate may occur through inhalation and dermal contact with this compound at workplaces where Diphenyl carbonate is produced or used.

Safety Information of Diphenyl carbonate:
Signal Word: Warning
Hazard Statements: H302 - H410
Precautionary Statements: P264 - P270 - P273 - P301 + P312 - P391 - P501
Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2
Storage Class Code: 13 - Non Combustible Solids
WGK: WGK 1
Flash Point(F): 334.4 °F - closed cup
Flash Point(C): 168 °C - closed cup
Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves

Accidental Release Measures of Diphenyl carbonate:
Personal precautions, protective equipment and emergency procedures:
For indoor, provide adequate ventilation process until the end of working.

Deny unnecessary entry other thanthepeopleinvolved by, for example, using a rope.
While working, wear appropriate protective equipments to avoid adheringit onskin, or inhaling the gas.

Work from windward, and retract the people downwind.
Environmental precautions:
To be careful not discharged to the environment without being properly handled waste water contaminated.

Methods and materials for contaminent and methods and materials for cleaning up:
Sweep up and gather scattered particles, and collect Diphenyl carbonate in an empty airtight container.

Recoverly, neutralization:
No information available

Secondary disaster prevention measures:
Clean contaminated objects and areas thoroughly observing environmental regulations.

Disposal Methods of Diphenyl carbonate:
At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision.
Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Antidote and Emergency Treatment of Diphenyl carbonate:
Basic Treatment: Establish a patent airway.
Suction if necessary.

Watch for signs of respiratory insufficiency and assist ventilations if necessary.
Administer oxygen by nonrebreather mask at 10 to 15 L/min.

Monitor for pulmonary edema and treat if necessary.
Monitor for shock and treat if necessary.

For eye contamination, flush eyes immediately with water.
Irrigate each eye continuously with normal saline during transport.

Do not use emetics.
For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool.
Administer activated charcoal.

Advanced Treatment:
Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious.
Positive pressure ventilation techniques with a bag valve mask device may be beneficial.

Monitor cardiac rhythm and treat arrhythmias if necessary.
Start an IV with D5W /SRP: "To keep open", minimal flow rate.

Use lactated Ringer's if signs of hypovolemia are present.
Watch for signs of fluid overload.

For hypotension with signs of hypovolemia, administer fluid cautiously.
Consider vasopressors if patient is hypotensive with a normal fluid volume.

Watch for signs of fluid overload.
Consider drug therapy for pulmonary edema.
Use propaparacaine hydrochloride to assist eye irrigation.

First Aid Measures of Diphenyl carbonate:

Inhalation:
Remove to fresh air.
If symptoms persist, call a physician.

Skin contact:
Wash off immediately with soap and plenty of water.
If symptoms persist, call a physician.

Eye contact:

If in eyes: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do.
Continuerinsing.
Immediate medical attention is required.

Ingestion:
Rinse mouth.
Never give anything by mouth to an unconscious person.
Call a physician or poison control center immediately.
Do not induce vomiting without medical advice.

Protection of first-aiders:
Use personal protective equipment as required.

Fire Fighting Measures of Diphenyl carbonate:

Suitable extinguishing media:
Water spray (fog), Carbon dioxide (CO2), Foam, Extinguishing powder, Sand

Unsuitable extinguishing media:
No information available

Specific hazards arising from the chemical product:
Thermal decomposition can lead to release of irritating and toxic gases and vapors.

Special extinguishing method:
No information available

Special protective actions for fire-fighters:
Use personal protective equipment as required.
Firefighters should wear self-contained breathing apparatus andfull firefighting turnout gear.

Identifiers of Diphenyl carbonate:
CAS Number: 102-09-0
ChEBI: CHEBI:34722
ChemSpider: 7315
ECHA InfoCard: 100.002.733
KEGG: C14507
PubChem CID: 7597
UNII: YWV401IDYN
CompTox Dashboard (EPA): DTXSID3020540
InChI:
InChI=1S/C13H10O3/c14-13(15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H
Key: ROORDVPLFPIABK-UHFFFAOYSA-N check
InChI=1/C13H10O3/c14-13(15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H
Key: ROORDVPLFPIABK-UHFFFAOYAY
SMILES: O=C(Oc1ccccc1)Oc2ccccc2

Properties of Diphenyl carbonate:
Chemical formula: C13H10O3
Molar mass: 214.216 g/mol
Density: 1.1215 g/cm3 at 87 °C
Melting point: 83 °C (181 °F; 356 K)
Boiling point: 306 °C (583 °F; 579 K)
Solubility in water: insoluble
Solubility: soluble in ethanol, diethyl ether, carbon tetrachloride, acetic acid

Quality Level: 200
Assay: 99%
Form: crystals
bp: 301-302 °C (lit.)
mp: 79-82 °C (lit.)
SMILES string: O=C(Oc1ccccc1)Oc2ccccc2
InChI: 1S/C13H10O3/c14-13(15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H
InChI key: ROORDVPLFPIABK-UHFFFAOYSA-N

Molecular Weight: 214.22
XLogP3: 3.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 4
Exact Mass: 214.062994177
Monoisotopic Mass: 214.062994177
Topological Polar Surface Area: 35.5 Ų
Heavy Atom Count: 16
Complexity: 193
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Diphenyl carbonate:
Color: White
Melting Point: 78.0°C to 81.0°C
Boiling Point: 301.0°C to 302.0°C
Flash Point: 168°C
Assay Percent Range: 98.5% min. (GC)
Infrared Spectrum: Authentic
Linear Formula: (C6H5O)2CO
Beilstein: 06,158
Packaging: Plastic bottle
Merck Index: 15,3354
Quantity: 1kg
Solubility Information: Solubility in water: insoluble. Other solubilities: solulbe in acetone, hot alcohol, benzene, carbon, tetrachloride, ether, glacial acetic acid and, other organic solvents
Formula Weight: 214.22
Physical Form: Flakes or Crystalline Powder
Percent Purity: 99%
Chemical Name or Material: Diphenyl carbonate

Related Products of Diphenyl carbonate:
1-(3,5-dichloropyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
1,3-dimethyl-1H,4H,5H,6H-pyrazolo[3,4-b][1,4]thiazin-5-one
2-(3,5-dichlorophenyl)-2-(ethylamino)acetic acid hydrochloride
6,7-dichloro-2-methyl-2,3-dihydro-1-benzofuran-3-one
2-{[(3,4-dichlorophenyl)carbamoyl]amino}-3-(1H-indol-3-yl)propanoic acid

Names of Diphenyl carbonate:

Regulatory process names:
Carbonic acid, diphenyl ester
Diphenyl carbonate
Diphenyl carbonate
diphenyl carbonate
Phenyl carbonate
Phenyl carbonate ((PhO)2CO)

CAS names:
Carbonic acid, diphenyl ester

IUPAC names:
Diphenyl Carbonate
Diphenyl carbonate
diphenyl carbonate
Diphenyl carbonate
Diphenylcarbonat
DPC

Preferred IUPAC name:
Diphenyl carbonate

Trade names:
Carbonic acid diphenyl ester
Diphenyl carbonate
DPC
EF-1032
EN-1052
HF-3200H
HI-1001BS
HM-1150S
HN-3104
HN-3104R
LB-3150G
NE-1010
NE-1030
NF-3017
NH-1000T
NH-1015
NH-1015V
NH-1017D
NH-1017SG
PC00-SC-1060U00
PC00-SC-1080F00
PC00-SC-1100R00
PC00-SC-1100UR0
PC00-SC-1220R00
PC00-SC-1220UR0
PC00-SC-1280UR0
SA-1220
TN-1045M
VB-1202F
WP-1041G
WP-1069
WR-7350

Other name:
Phenyl carbonate, di-
DIPHENYL ETHER
DIPOTASSIUM AZELATE, N° CAS : 52457-54-2, Nom INCI : DIPOTASSIUM AZELATE. Nom chimique : Dipotassium nonanedioate. N° EINECS/ELINCS : 257-931-2. Ses fonctions (INCI): Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
DIPICOLINIC ACID

Dipicolinic acid, often abbreviated as DPA, is a chemical compound with the molecular formula C7H5NO4.
Dipicolinic acid is a derivative of pyridine and is known for its role in bacterial endospores, specifically as a major component of the spore core.
The chemical structure of dipicolinic acid includes a pyridine ring and carboxylic acid functional groups.

CAS Number: 499-83-2
EC Number: 207-838-8



APPLICATIONS


Dipicolinic acid is used as a diagnostic marker for microbiological testing, indicating the presence of bacterial endospores.
In the food industry, dipicolinic acid detection serves as an indicator for spore contamination, ensuring food safety.
Dipicolinic acid plays a crucial role in detection kits designed to identify potential biological warfare agents, such as anthrax spores.

Dipicolinic acid is employed in assessing the efficacy of sterilization processes, especially in healthcare settings.
Researchers use dipicolinic acid to study the physiology, structure, and germination of bacterial spores.

Dipicolinic acid has applications in medical diagnostics, assisting in the identification of specific bacterial infections.
Understanding dipicolinic acid's role in spore formation contributes to the development of bioremediation strategies using spore-forming bacteria.
The study of dipicolinic acid aids in the development of pharmaceuticals targeting bacterial spores.

Detection methods involving dipicolinic acid are crucial for biosecurity measures to identify and respond to potential bioterrorism threats.
Research on dipicolinic acid sheds light on spore resistance mechanisms, influencing strategies for environmental control.

In veterinary science, dipicolinic acid is utilized for diagnosing bacterial infections in animals caused by spore-forming bacteria.
Dipicolinic acid serves as a valuable tool in biological research, elucidating the unique properties and functions of bacterial endospores.
Dipicolinic acid is a key component in the validation of pharmaceutical sterilization processes, ensuring the elimination of bacterial spores.

Dipicolinic acid detection is used in environmental monitoring to assess the prevalence of spore-forming bacteria in various ecosystems.
Understanding dipicolinic acid contributes to the development of biological preservation methods for cultures and specimens.
Dipicolinic acid is involved in studies focused on the decontamination of surfaces and environments contaminated with bacterial spores.

In biotechnological applications, dipicolinic acid is considered in the design of spore-based systems for various purposes, such as biosensing.
Dipicolinic acid detection is applied in agricultural microbiology to study the role of spore-forming bacteria in soil health.

Dipicolinic acid contributes to microbial ecology studies by helping researchers understand the prevalence and impact of spore-forming organisms in diverse environments.
Dipicolinic acid assists in phylogenetic studies, aiding in the classification and identification of bacteria based on their spore-forming capabilities.
Research explores the potential of incorporating dipicolinic acid into drug delivery systems, leveraging the unique properties of spores.
Detection methods involving dipicolinic acid are employed in monitoring water quality to assess the presence of spore-forming bacteria.

The study of dipicolinic acid contributes to understanding the dynamics of soil microbial communities influenced by spore-forming bacteria.
Dipicolinic acid's resistance to harsh conditions has implications for astrobiology, particularly in studying the survival potential of spores in space environments.
Dipicolinic acid plays a role in exploring biological control strategies, utilizing spore-forming bacteria for targeted intervention in various settings.

Dipicolinic acid is being explored for potential applications in the cosmetic industry, particularly in formulations designed for skin health and protection.
Research involving dipicolinic acid contributes to understanding the radiation resistance mechanisms of spore-forming bacteria, relevant in fields such as radiation therapy and space exploration.

Investigations into dipicolinic acid's biodegradability inspire the development of biodegradable materials, aligning with environmentally friendly initiatives.
The study of spore-forming bacteria and dipicolinic acid aids in developing strategies to mitigate biofouling, particularly in marine environments.

Dipicolinic acid is explored for potential pharmacological applications, including its interaction with specific receptors and its impact on cellular processes.
Research suggests potential applications of dipicolinic acid in dental health, considering its antimicrobial properties against spore-forming bacteria in oral environments.
Investigations into dipicolinic acid's properties contribute to advancements in microbial fuel cell technology, where spore-forming bacteria are used for energy production.

Understanding spore-forming bacteria and dipicolinic acid aids in the development of eco-friendly approaches to oil spill remediation.
Dipicolinic acid's role in spore resistance mechanisms has implications in the development of novel food preservation methods, improving shelf life and safety.

Researchers explore dipicolinic acid's potential as a target for novel antibiotics, aiming to disrupt bacterial spore formation and viability.
The study of dipicolinic acid contributes to the development of biological soil amendments, enhancing soil fertility and microbial diversity.
Understanding spore-forming bacteria and dipicolinic acid is relevant in designing probiotic formulations with extended stability and viability.
Dipicolinic acid detection methods find applications in water treatment processes to monitor and control the presence of spore-forming bacteria.

The unique properties of dipicolinic acid inspire the development of biosensors for rapid and sensitive detection of bacterial spores in various environments.
Researchers explore dipicolinic acid's role in spore resistance as a potential target for vaccine development against spore-forming pathogens.

Dipicolinic acid is employed in various chemical analysis techniques, contributing to advancements in analytical chemistry.
Studies on dipicolinic acid may have implications in medical imaging, potentially serving as a contrast agent or marker for certain conditions.
The properties of dipicolinic acid influence the development of antimicrobial coatings, with applications in healthcare settings and beyond.
Research on dipicolinic acid aids in understanding its fate and impact in wastewater treatment processes, ensuring environmental safety.

Dipicolinic acid is utilized as a biological indicator in sterilization processes, providing a reliable measure of spore destruction.
Dipicolinic acid's stability and unique properties are harnessed in molecular biology techniques, including DNA extraction methods.

The study of spore-forming bacteria and dipicolinic acid contributes to the development of sustainable strategies for crop protection against certain pathogens.
Dipicolinic acid is investigated for potential applications in tissue engineering, leveraging its properties in scaffold design and cellular interactions.
Dipicolinic acid serves as an indicator in environmental impact studies, providing insights into the prevalence and effects of spore-forming bacteria.

The stability of dipicolinic acid is considered in the preservation of cultural heritage artifacts, where spore-forming bacteria may be present.
Dipicolinic acid's stability under extreme conditions makes it relevant in space exploration, where bacterial spores might be present, influencing spacecraft sterilization protocols.

In healthcare settings, dipicolinic acid is employed as a biological indicator to assess the effectiveness of sterilization procedures in medical instruments.
The study of dipicolinic acid contributes to the development of environmentally friendly approaches for biological pest control, leveraging spore-forming bacteria against pests.
Dipicolinic acid's stability properties are considered in pharmaceutical formulations, potentially enhancing the stability of certain medications.
Spore-forming bacteria and dipicolinic acid are investigated for their potential role in MEOR processes to improve oil recovery from reservoirs.
Dipicolinic acid inspires the development of biological sensors that can detect spore-forming bacteria in real-time, aiding in environmental monitoring.

Research on dipicolinic acid contributes to strategies for disrupting biofilms, especially those formed by spore-forming bacteria in industrial and medical settings.
The properties of dipicolinic acid are explored for their potential in soil remediation, particularly in addressing contamination by spore-forming bacteria.
The study of dipicolinic acid has implications in the development of veterinary pharmaceuticals targeting spore-forming bacterial infections in animals.

Dipicolinic acid is considered in the development of probiotic formulations for agriculture, enhancing plant growth and resistance to certain pathogens.
Dipicolinic acid serves as an indicator for the cleanliness of cleanroom environments, particularly in industries requiring stringent hygiene standards.

The unique properties of dipicolinic acid contribute to synthetic biology applications, where spore-forming organisms are engineered for specific purposes.
Research explores the incorporation of dipicolinic acid into materials, influencing their mechanical and chemical properties for various applications.

Understanding dipicolinic acid aids in the development of countermeasures against potential biological warfare threats involving spore-forming bacteria.
The presence of dipicolinic acid in spores contributes to biogeochemical cycling, influencing nutrient dynamics in various ecosystems.
Dipicolinic acid's role in cellular differentiation is studied in stem cell research, exploring its impact on cell fate and tissue development.
Spore-forming bacteria and dipicolinic acid are considered in optimizing fermentation processes, such as those used in the production of certain foods and beverages.

Dipicolinic acid is investigated for its potential applications in industrial biotechnology, particularly in the development of bio-based products.
The metal chelation properties of dipicolinic acid are explored for potential applications as a sorbent in the removal of specific metal ions from solutions.

The prevalence of spore-forming bacteria and dipicolinic acid contributes to climate change studies, impacting carbon and nitrogen cycling in ecosystems.
Dipicolinic acid's optical properties inspire research into its potential use in the development of photonic materials for technological applications.

Understanding dipicolinic acid aids in engineering microbial consortia for specific functions, such as enhanced nutrient cycling or bioremediation.
The detection of dipicolinic acid is explored for its potential as a biomarker in disease diagnosis, offering insights into specific bacterial infections.
Research investigates the catalytic properties of dipicolinic acid for potential applications in chemical synthesis and transformation reactions.
Dipicolinic acid's stability is considered in the preservation of biological specimens in museums, where spores might be present.



DESCRIPTION


Dipicolinic acid, often abbreviated as DPA, is a chemical compound with the molecular formula C7H5NO4.
Dipicolinic acid is a derivative of pyridine and is known for its role in bacterial endospores, specifically as a major component of the spore core.
The chemical structure of dipicolinic acid includes a pyridine ring and carboxylic acid functional groups.

The significance of dipicolinic acid lies in its association with bacterial spores, where it contributes to the heat resistance and dehydration resistance of the spore core.
During the formation of spores, dipicolinic acid is complexed with calcium ions, forming a stable salt known as calcium dipicolinate.
Dipicolinic acid plays a crucial role in the resistance of bacterial spores to harsh environmental conditions.

Dipicolinic acid is characterized by a distinct molecular structure featuring a pyridine ring and two carboxylic acid groups.
With the chemical formula C7H5NO4, it belongs to the class of heterocyclic compounds known as pyridine carboxylic acids.
Dipicolinic acid is a critical component of bacterial endospores, contributing to their heat and dehydration resistance.

In bacterial spores, dipicolinic acid forms a stable complex with calcium ions, known as calcium dipicolinate.
The presence of dipicolinic acid in spores is a key biological feature, providing protection against environmental stresses.

Dipicolinic acid is thermally stable, contributing to the spore's ability to withstand high temperatures during processes like autoclaving.
Its role in dehydration resistance is essential for the survival of bacterial spores in unfavorable conditions.
Dipicolinic acid is linked to the dormancy of endospores, allowing bacteria to endure extended periods of environmental adversity.
The complexation of dipicolinic acid with calcium contributes to microbial resistance against various decontamination methods.

Dipicolinic acid serves as an analytical marker for the detection of bacterial endospores in certain diagnostic and research applications.
The environmental persistence of dipicolinic acid in spores plays a crucial role in the life cycle of spore-forming bacteria.

The ability to chelate calcium ions showcases its metal-binding properties, influencing the structural stability of the spore core.
While it is a natural compound, its biodegradability may vary based on environmental conditions.
The presence of dipicolinic acid contributes to the functionality and resilience of microbial spores.
Its interaction with metal ions, particularly calcium, is essential for the formation and stability of the calcium dipicolinate complex.

Dipicolinic acid is a characteristic feature of spore-forming bacteria, aiding in their classification and identification.
In some contexts, dipicolinic acid is used as an indicator for the presence of bacterial spores, including those potentially used in biological warfare.
Its stability under high-temperature sterilization processes makes it a valuable indicator for the effectiveness of sterilization methods.

Dipicolinic acid is utilized in laboratory research as a tool to study bacterial spore properties and resistance mechanisms.
Its coordination chemistry, particularly its ability to coordinate with metal ions, is a subject of interest in chemical research.

Understanding the properties of dipicolinic acid has implications in biotechnological applications, including spore-based bioremediation.
During germination, dipicolinic acid is released from the spore, playing a role in spore activation.

The concentration of dipicolinic acid in spores is linked to their viability and ability to re-enter active growth phases.
Research into the role of dipicolinic acid extends to understanding host-pathogen interactions and bacterial virulence.
While primarily associated with bacterial spores, dipicolinic acid also occurs naturally in certain plants and marine organisms.



PROPERTIES


Chemical Formula: C7H5NO4
Molecular Weight: Approximately 167.12 g/mol
Chemical Structure: Features a pyridine ring and two carboxylic acid groups.
Melting Point: Decomposes before melting.
Solubility: Soluble in water, but the solubility may vary with temperature.
Acidity/Basicity: Exhibits weak acidic properties due to the carboxylic acid groups.
Stability: Stable under normal conditions; however, decomposes under high temperatures.
Biodegradability: The biodegradability of dipicolinic acid may vary based on environmental conditions.
Complex Formation: Forms stable complexes, particularly with calcium ions, known as calcium dipicolinate.
pKa Values: The acidity constants (pKa values) of the carboxylic acid groups influence its behavior in solution.
Chemical Reactivity: Reacts with various metal ions, influencing its role in the formation of stable complexes.



FIRST AID


Inhalation:

If inhaled, move the affected person to an area with fresh air.
Allow the person to rest in a comfortable position.
Seek medical attention promptly.
If the person is not breathing, administer artificial respiration. If trained, perform CPR.


Skin Contact:

Remove contaminated clothing immediately.
Wash the affected skin area gently with soap and water for at least 15 minutes.
Seek medical attention if irritation, redness, or other adverse effects persist.


Eye Contact:

Rinse the eyes immediately with plenty of water, ensuring the eyelids are held open.
Continue rinsing for at least 15 minutes.
Seek immediate medical attention, and bring the product's Safety Data Sheet if available.


Ingestion:

If swallowed, do not induce vomiting unless directed by medical personnel.
Rinse the mouth with water and drink plenty of water (if conscious).
Seek immediate medical attention.
Do not give anything by mouth to an unconscious person.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves, safety goggles, and a lab coat, to prevent skin contact and eye exposure.
Use respiratory protection if working with the substance in an area with inadequate ventilation.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.

Avoidance of Contact:
Minimize direct contact with the substance.
Handle with tools or equipment designed for the specific task.

Preventive Measures:
Implement good industrial hygiene practices, including regular handwashing and avoiding unnecessary exposure.

Spill Response:
In the event of a spill, use appropriate spill control measures, such as absorbent materials, to contain and clean up the spill.

Avoiding Ingestion:
Do not eat, drink, or smoke in areas where dipicolinic acid is handled.

Equipment Cleanliness:
Ensure that all equipment used is clean and free of contaminants to prevent unintended reactions or contamination.

Labeling:
Clearly label all containers with the name of the substance, hazard information, and necessary precautionary measures.

Training:
Provide training to personnel handling dipicolinic acid on its properties, safe handling procedures, and emergency response.


Storage:

Container Selection:
Store dipicolinic acid in tightly sealed containers made of compatible materials, such as glass or plastic.
Use containers that are resistant to the substance to prevent leakage or deterioration.

Storage Conditions:
Store in a cool, dry place away from direct sunlight and incompatible substances.
Maintain storage temperatures as recommended in the product's Safety Data Sheet.

Ventilation:
Ensure adequate ventilation in storage areas to prevent the buildup of airborne concentrations.

Segregation:
Store dipicolinic acid away from incompatible materials, including strong acids, bases, and oxidizing agents.

Avoiding Contamination:
Prevent contamination by storing dipicolinic acid separately from other chemicals to avoid unintended reactions.

Access Control:
Restrict access to storage areas to authorized personnel only.

Security Measures:
Implement security measures to prevent unauthorized access or theft.

Emergency Equipment:
Ensure that emergency equipment, such as eyewash stations and safety showers, is readily accessible in the storage area.



SYNONYMS


Pyridine-2,6-dicarboxylic acid
2,6-Pyridinedicarboxylic acid
Pyridine-2,6-dicarboxylate
Bis-pyridine-2,6-dicarboxylic acid
2,6-Dicarboxypyridine
2,6-Pyridine dicarboxylic acid
2,6-Pyridine-dicarboxylic acid
Pyridine-2,6-biscarboxylic acid
Bis(2-carboxypyridyl)methane
2,6-Dicarboxy pyridine
Pyridine-2,6-diyl dicarboxylate
Dipyridine-2,6-dicarboxylate
Bis-picolinic acid
2,6-Pyridyl dicarboxylic acid
2,6-Picolinic acid
Bis-pyridyl dicarboxylic acid
2,6-Dicarboxylpyridine
2,6-Dicarboxylic acid pyridine
2,6-Pyridine dicarboxylate
Dipicolinate
2,6-Dicarboxypyridine
2,6-Pyridine-dicarboxylic acid
2,6-Biscarboxypyridine
Pyridine-2,6-dicarboxylate
2,6-Dicarboxypyridine
Bipyridinedicarboxylic acid
2,6-Pyridinedicarboxylic acid
Pyridine-2,6-dicarboxylic acid
Bis(2-carboxypyridyl)methane
2,6-Bis(carboxypyridyl)methane
2,6-Dicarboxypyridine
2,6-Picolinic acid
2,6-Dicarboxylpyridine
Pyridine-2,6-bis(carboxylic acid)
Pyridine-2,6-dicarboxylate
Dipyridine-2,6-dicarboxylate
2,6-Dicarboxy pyridine
2,6-Pyridyl dicarboxylic acid
Bis-pyridine-2,6-dicarboxylic acid
2,6-Pyridine dicarboxylic acid
Pyridine-2,6-diyl dicarboxylate
Bis-pyridyl dicarboxylic acid
Pyridine-2,6-dicarboxylate
2,6-Dicarboxy pyridine
2,6-Pyridine dicarboxylate
Pyridine-2,6-dicarboxylic acid
Bis(2-carboxypyridyl)methane
2,6-Bis(carboxypyridyl)methane
2,6-Dicarboxypyridine
2,6-Picolinic acid
DIPOTASSIUM AZELATE
DIPOTASSIUM EDTA, N° CAS : 2001-94-7, Nom INCI : DIPOTASSIUM EDTA. Nom chimique : Dipotassium dihydrogen ethylenediaminetetraacetate. N° EINECS/ELINCS : 217-895-0. Agent de chélation : Réagit et forme des complexes avec des ions métalliques qui pourraient affecter la stabilité et / ou l'apparence des produits cosmétiques
DIPOTASSIUM EDTA
Phosphoric acid, dipotassium salt; Dipotassium hydrogen orthophosphate; Dipotassium hydrogenphosphate; Potassium phosphate, dibasic; Potassium hydrogen phosphate; DIBASIC POTASSIUM PHOSPHATE; DI-POTASSIUM HYDROGEN ORTHOPHOSPHATE; di-Potassium hydrogen orthophosphate anhydrous; DI-POTASSIUM HYDROGEN PHOSPHATE; DIPOTASSIUM PHOSPHATE; DI-POTASSIUM PHOSPHATE DIBASIC; DKP; MONOPOTASSIUM PHOSPHATE; POTASSIUM BIPHOSPHATE; POTASSIUM HYDROGEN PHOSPHATE; POTASSIUM HYDROGEN PHOSPHATE, DIBASIC; POTASSIUM MONOHYDROGEN PHOSPHATE; POTASSIUM MONOPHOSPHATE; POTASSIUM PHOSPHATE, DIBASIC; SEC-POTASSIUM PHOSPHATE; dikaliumphosphate; dipotassiummonohydrogenphosphate; dipotassiummonophosphate; dipotassium-o-phosphate; dipotassiumorthophosphate CAS NO:7758-11-4
DIPOTASSIUM HYDROGEN PHOSPHATE
DIPOTASSIUM PHOSPHATE, N° CAS : 7758-11-4, Nom INCI : DIPOTASSIUM PHOSPHATE, Nom chimique : Dipotassium hydrogenorthophosphate, N° EINECS/ELINCS : 231-834-5, Ses fonctions (INCI). Anticorrosif : Empêche la corrosion de l'emballage. Régulateur de pH : Stabilise le pH des cosmétiques
DIPOTASSIUM PHOSPHATE
DIPOTASSIUM PHOSPHATE = DKP = POTASSIUM HYDROGEN PHOSPHATE


CAS Number: 7758-11-4
EC Number: 231-834-5
MDL Number: MFCD00011383
Chemical Formula: K2HPO4


Dipotassium Phosphate, Food Grade appears as white crystals or powder.
Dipotassium phosphate is the dipotassium salt of phosphoric acid, is hygroscopic, and has no odor.
Dipotassium phosphate is very soluble in water and slightly soluble in alcohol.


Dipotassium Phosphate, Anhydrous (DKPa) Granular / Powder is a powder product featuring key properties such as easy handling, excellent buffering capacity, nutrient source capability, alkalinity, and precipitating agent uses.
Dipotassium phosphate is an excellent, highly soluble buffer for casein based coffee creamers.


The use of Dipotassium phosphate stabilizes the protein layer around the fat droplets thus preventing syneresis and curdling of the protein when added to hot, acidic coffee or tea.
Dipotassium Phosphate is an inorganic salt.


Dipotassium phosphate is formed when two equivalents of potassium react with phosphoric acid until the desired PH is obtained.
Solution is then further dried to get fine quality white powder.
Dipotassium phosphate also known as potassium hydrogen orthophosphate and potassium phosphate dibasic, is a highly water-soluble salt which is often used as a fertilizer, food additive and buffering agent.


Dipotassium phosphate is a common source of phosphorus and potassium.
Dipotassium phosphate (K2HPO4) (also dipotassium hydrogen orthophosphate; potassium phosphate dibasic) is the inorganic compound with the formula K2HPO4.(H2O)x (x = 0, 3, 6).
Together with monopotassium phosphate (KH2PO4.(H2O)x), Dipotassium phosphate is often used as a fertilizer, food additive, and buffering agent.


Dipotassium phosphate is a white or colorless solid that is soluble in water.
Dipotassium phosphate is produced commercially by partial neutralization of phosphoric acid with two equivalents of potassium chloride:
H3PO4 + 2 KCl → K2HPO4 + 2 HCl
As a food additive, dipotassium phosphate is categorized by the United States Food and Drug Administration as generally recognized as safe.


Dipotassium phosphate is a potassium salt that is the dipotassium salt of phosphoric acid.
Dipotassium phosphate has a role as a buffer.
Dipotassium phosphate is a potassium salt and an inorganic phosphate.


Dipotassium phosphate is the dipotassium form of phosphoric acid, that can be used as an electrolyte replenisher and with radio-protective activity.
Upon oral administration, Dipotassium phosphate is able to block the uptake of the radioactive isotope phosphorus P 32 (P-32).


Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Dipotassium phosphate is a reagent with a very high buffering capacity.


Dipotassium phosphate is widely used in molecular biology, biochemistry, and chromatography.
Potassium phosphate occurs in several forms: monobasic (KH2PO4), dibasic (K2HPO4), and tribasic (K3PO4).
Neutral potassium phosphate buffer solutions may be prepared with a mixture of the monobasic and dibasic forms to varying degrees, depending on the desired pH.


Dipotassium phosphate buffers are very useful in numerous applications, but with the following limitations: precipitation of Ca2+ and Mg2+, inhibition of restriction enzyme activity, and interference in DNA ligation or bacterial transformation protocols.
Dipotassium phosphate as been used to study the effects of freezing and thawing on the stability of proteins sensitive to conformational changes; it was found that Potassium Phosphate, Dibasic, Anhydrous buffers offered improved pH stability as opposed to NaP buffers.


Dipotassium phosphate has also been used for the extraction of keratohyalin protein from bovine tissue.
Dipotassium phosphate is also known as Dipotassium hydrogenphosphate, Dipotassium phosphate, and sec.-Potassium phosphate.
Dipotassium phosphate (DKP) is a multi-purpose food additive.
Not only does Dipotassium phosphate allow for certain foods to be shelf-stable and appealing, but you get the added benefit of potassium.


Without Dipotassium phosphate , many dairy-based coffee creamers, cheese products and any other food that is lacking in potassium would not be possible without the use of other, possibly more expensive, ingredients that do not have the additional benefit of potassium.
Dipotassium phosphate is an ingredient you’ll find in many boxed milks that gets little attention.
Dipotassium phosphate is a chemical compound commercially made by combining phosphate, phosphorus, and sodium.


This results in a white powdery substance that easily dissolves in liquid and can be used as a fertilizer, food additive, or buffering agent.
Dipotassium Phosphate is a food additive.
Dipotassium Phosphate is “generally recognized as safe” (GRAS) by the U.S. Food and Drug Administration (FDA).
Phosphates like Dipotassium Phosphate are derived from the element phosphorus.


Dipotassium Phosphate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Dipotassium phosphate is produced when Phosphoric acid reacts with a couple of equivalents until the desired pH value of achieved.


Dipotassium phosphate is available in white fine powder. As the name suggests, Dipotassium phosphate is pure in its form and is ideal to be used for industrial purpose.
Dipotassium phosphate is highly economical and can be easily bought by customers of all budgets without thinking twice.


A thorough research is conducted before carrying out the chemical reaction to obtain Dipotassium phosphate.
Dipotassium phosphate is made from high grade chemical and it is a product of high purity and high chemical stability.
Dipotassium phosphate is highly utilized as a food addictive and also in non-dairy creamers to prevent coagulation.


Dipotassium phosphate is freely soluble in water and it is in white powder form.
Dipotassium phosphate is a water soluble salt categorised as a safe food additive by the food and drug administration board.
Dipotassium phosphate is used to increase shelf life or enhance the texture of products within the food and beverage industry.
Dipotassium phosphate (DKP) is a water-soluble salt that usually comes in the form of a colourless, white substance.


Commercially, Dipotassium phosphate is known as a food additive, fertiliser, and buffering agent.
For health and fitness, dipotassium phosphate supplements are sought for the part they play in the production of ATP (adenosine triphosphate), which is a high-energy molecule that your body requires for energy.
Dipotassium phosphate is a top source of potassium and phosphorus.


This is where the ‘phosphate’ part comes in.
Phosphate is a charged particle that contains the mineral phosphorus.
Your body needs this to be able to maintain, repair and rebuild your healthy teeth and bones.
Not only this, but phosphate makes your muscles contract and function as they should.


Dipotassium Phosphate is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorous and potassium, as well as a buffering agent.
Dipotassium phosphate, also known as potassium phosphate dibasic.
The dipotassium phosphate formula is K2HPO4. It is highly water-soluble and frequently used as a fertilizer and food additive.


Dipotassium phosphate is a common source of phosphorus and potassium.
Dipotassium phosphate (K2HPO4) is a common source of phosphorus and potassium.
Dipotassium phosphate is a water-soluble salt, sought for its role in the production of ATP, a molecule your body uses for energy.
Dipotassium Phosphate is the dipotassium salt of phosphoric acid with the chemical formula K2HPO4.


Dipotassium phosphate is freely soluble in water and insoluble in ethanol.
The reaction chemistry for the production of dipotassium phosphate appears as a condensation of phosphoric acid using potassium hydroxide.
Phosphoric acid is in turn manufactured from phosphate rock, which is found in several places throughout the world.


Dipotassium phosphate has role buffer.
Dipotassium phosphate is a inorganic phosphate.
Dipotassium phosphate is a potassium salt .



USES and APPLICATIONS of DIPOTASSIUM PHOSPHATE:
As a food additive, dipotassium phosphate is used in imitation dairy creamers, dry powder beverages, mineral supplements, and starter cultures.
Dipotassium phosphate functions as an emulsifier, stabilizer and texturizer.
Dipotassium phosphate also is a buffering agent, and chelating agent especially for the calcium in milk products.


Some common foods that have Dipotassium phosphate are Whipped cream, Cheese, Ice cream, Milk, Yogurt, Seafood, Meat, Pasta, Soda, Gelatin powder.
Dipotassium phosphate is used in some makeups, skin creams, and shampoos.
The grades of dipotassium hydrogen phosphate used in foods are different than that which are used in fertilisers.


Dipotassium phosphate is common in many cosmetics such as Mouthwash, Foundation, Hair dye and bleach, Skincare creams, Sunscreen.
Other products and processes containing Dipotassium phosphate include Laxatives, Fireproofing material, Water treatment, Various medications.
Dipotassium phosphate is used in fertilisers.


Dipotassium phosphate is used as a component of fertilisers because of its highly water-soluble nature.
Dipotassium phosphate supplies the growing plants with a large percentage of phosphorus.
Dipotassium phosphate is used as a food additive.


Dipotassium phosphate is added in milk to increase its pH.
This is done in order to increase the net micelle charge.
Micelles are aggregates of molecules.
Dipotassium phosphate is used in the micelles as a competitive displacement of calcium by sodium.


Dipotassium Phosphate (DKP) is an effective buffering agent for a range of balancing agent-functioning uses.
Dipotassium Phosphate is highly effective in preventing coagulation when used as a food additive or preservative and is generally used as a buffering agent on the non-dairy creamer market.
Dipotassium phosphate is used as a buffering agent in antifreeze solution


Dipotassium phosphate forms a key ingredient for instant fertilizers
Dipotassium phosphate is efficient source of nutrition in culturing of antibiotics
Dipotassium phosphate is also used as sequestrant in the preparation of non-dairy powdered coffee creams


Dipotassium phosphate is also used in production of trypti case soy agar which is then further processed to agar plates for culturing bacteria
Dipotassium phosphate , used in various chemical processes as a phosphorylating compound.
Also used in the preparation of prosthetics and collagen nanocomposites due to the bone-like properties.


Dipotassium phosphate is used in Agricultural Chemicals, Animal Nutrition & Feed, Buffering Agents, Food & Beverage, Food Additives
Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.


Dipotassium phosphate is used in imitation dairy creamers, dry powder beverages, mineral supplements, and starter cultures as an additive.
Dipotassium phosphate is used in non-dairy creamers to prevent coagulation.
Dipotassium phosphate is also used to make buffer solutions and it is used in the production of trypticase soy agar which is used to make agar plates for culturing bacteria.


Dipotassium phosphate is used in the chemical industry and in the fertilizers.
Dipotassium phosphate is used in Chemical industry, Fertilizers.
Dipotassium phosphate is used as a mineral supplement for pharmaceuticals and as a nutrient source during yeast production and other fermentation processes.


Dipotassium phosphate also helps buffer the pH of the cheese and interacts with milk proteins to promote emulsification.
Used to maintain pH and to stabilize proteins when coffee whitener is added to coffee.
A synthetic salt that helps to adjust and maintain the pH of water-based and water soluble cosmetic formulas.


Dipotassium phosphate is also used in foods as a buffering agent to improve food texture, where it has GRAS (generally recognised as safe) status.
Dipotassium Phosphate (DKP) Dipotassium Phosphate is Generally Recognized As Safe (GRAS) for use in human foods, also considered GRAS for use in food generally as a multiple purpose food ingredient when used in accordance with Good Manufacturing Practice (cGMP).


Dipotassium Phosphate has several common functions, including Alkalinity Source, Sequestrant, Emulsifying Agent, Precipitating Agent, Buffering Agent, Protein Stablizer, Dispersant, Nutrient Source, Fermentation Nutrient, Anti-Feathering Agent and Acid Buffer in Non-Dairy Creamers, Whitener in Food Applications, Anti-Coagulant.


Common applications of Dipotassium Phosphate include Coffee Creamers
Dipotassium Phosphate is an excellent highly soluble buffer for casein based coffee creamers.
The use of Dipotassium Phosphate stabilizes the protein layer around the fat droplets, thus, preventing syneresis and curdling of the protein when added to hot, acidic coffee or tea.


Dipotassium phosphate is used as an emulsifier, stabilizer, and texturizer.
And in oat milk, specifically, Dipotassium phosphate is used as an acidity regulator to help the oat milk interact with coffee and also allow it to steam better.
Dipotassium phosphate is commonly used as a food additive and dietary supplement.


Dipotassium Phosphate is used to enhance food characteristics like nutritional value and cooking performance.
Dipotassium Phosphate is used in packaged foods, including macaroni and pastas.
Dipotassium Phosphate is also used in some cheeses as an emulsifier.
You can also find Dipotassium Phosphate in meat products, canned sauces, Jell-O, evaporated milk, and some chocolate.


Dipotassium Phosphate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Dipotassium Phosphate is used in the following products: fertilisers, anti-freeze products and washing & cleaning products.


Indoor uses of Dipotassium Phosphate includes machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners.
Release to the environment of Dipotassium Phosphate can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).


Dipotassium Phosphate can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery).
Dipotassium Phosphate is used in the following products: fertilisers, washing & cleaning products, anti-freeze products, air care products and laboratory chemicals.


Dipotassium Phosphate is used for the manufacture of: chemicals and machinery and vehicles.
Dipotassium Phosphate is used in the following products: fertilisers, washing & cleaning products, anti-freeze products, air care products, metal surface treatment products, pharmaceuticals and water treatment chemicals.


Dipotassium Phosphate is used in the following products: pH regulators and water treatment products, metal surface treatment products, pharmaceuticals, water treatment chemicals and fertilisers.
Dipotassium Phosphate is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and health services.


Dipotassium Phosphate is used for the manufacture of: chemicals, metals, fabricated metal products and machinery and vehicles.
Dipotassium phosphate functions as an effective buffering agent and sequestrant for a wide range of uses, including a balancing agent.
Used in Fertilizer, Food Additive, Imitation Dairy Creamers, Dry Powder Beverages, Mineral Supplements, Buffering agent, Pharmaceuticals.


As a food additive, Dipotassium phosphate is used in non-dairy creamers, dry powder beverages, and mineral supplements.
Dipotassium Phosphate is used in the following areas: agriculture, forestry and fishing, health services, building & construction work and scientific research and development.


Other uses include Fertilizer additive, Lab Reagent, Multi-purpose surfactant, Specialty fertilizer, Automotive antifreeze formulations, Nutrient for antibiotics, Pharmaceutical ingredient.
Dipotassium phosphate is a water soluble fertilizer and is used as a source of potassium and phosphorus.
Dipotassium phosphate plays an important role in the opening and closing of the stomata, which regulates the moisture balance of the plant.


Dipotassium phosphate also ensures the firmness of the plant cell.
Dipotassium phosphate also stimulates root growth and is a building block for cell walls.
Dipotassium phosphate is used in fertilizers.


Due to the highly water-soluble property Dipotassium phosphate is often used because it delivers a high amount of phosphorous to the growing plants.
Dipotassium phosphate is used as a food additive, but the grades are different for food versus fertilizer use.


Dipotassium phosphate is used to increase the pH of milk which would increase micellar net charge.
Dipotassium phosphate is used as a competitive displacement of calcium by sodium in the micelles.
Dipotassium phosphate is commonly used for the properties that make it effective as an emulsifier, stabiliser and texturiser.


In the food industry, dipotassium phosphate functions as an effective buffering agent and chelating agent, which may also be used for yeast food, emulsifying salt, and a synergistic agent of antioxidation.
Further to this dipotassium phosphate can be found on many a jar and packet label due to its use as a food additive.
Dipotassium phosphate's role here is to lower the acid levels in processed foods, along with lowering the sodium levels in low-sodium cheeses.


Dipotassium phosphate is also used as a stabiliser in non-dairy creamers to prevent coagulation.
Dipotassium phosphate is also edible and used for health benefits as a nutrient supplement and as a protein stabiliser in weight training drinks and powder mixes.


Dipotassium phosphate is used in potable water treatment
Dipotassium phosphate is used as a salt Dipotassium phosphate is most commonly used in the food and beverage market within the dairy industry.
Dipotassium phosphate is used as imitation dairy creamers Dipotassium phosphate helps to prevent coagulation in dairy free products.


As well as dairy products Dipotassium Phosphate is used in dry powder beverages, mineral supplements and starter cultures.
Dipotassium hydrogen phosphate (dipotassium phosphate) is a commonly used buffering agent and food additive, used as a source of phosphate in a variety of applications including cell culture and food analysis.


Dipotassium phosphate is used as Food and Beverage Chemicals - Sweeteners - Acidulants - Emulsifiers, Industrial Chemicals.
Applications include Industrial, food, medicine, Organic Synthesis, Plastic, Fertilizer, Rubber, Pharmaceutical, Water Treatment, Toothpastes, Nuclear, Paper, Oil Industry, Paints, Printing Industry, Textile Industry, Explosive, Lubricants, Metal
Processed Cheese Products: Dipotassium Phosphate helps buffer the pH and interact with the milk proteins to promote emulsification.


Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Potassium Phosphate, Dibasic is the dipotassium form of phosphoric acid, that can be used as an electrolyte replenisher and with radio-protective activity.


Upon oral administration, potassium phosphate is able to block the uptake of the radioactive isotope phosphorus P 32 (P-32).
Dipotassium phosphate is used as Buffer agent, Wastewater treatment, Anti-freeze, Water treatment, Ceramics, Pulp and paper, Paint and Coatings, Industries, Pulp & Paper, Coatings & Construction, Water Treatment, Agrobusiness and Chemical Processing.
Used in Canned milk, UHT milk, Cheese powders, Non-dairy creamers, Dairy, Beverages, Seafood, Cheese starter cultures.


-Dipotassium phosphate has a number of important applications in food:
Often used as a pH adjuster, buffer, and emulsifying agent
Commonly added to processed foods such as baked goods, dairy products, and beverages to improve texture, extend shelf life and enhance flavor
Commonly used for preventing coagulation for products that may separate while in transit, or on the shelf


-Nutrient Resource:
The potassium present in Dipotassium Phosphate can be used as a mineral supplement for pharmaceuticals and a nutrient base during yeast production and other fermentation processes.



WHAT TO KNOW ABOUT DIPOTASSIUM PHOSPHATE:
Dipotassium phosphate is a chemical added to foods, cosmetics, and other products.
Dipotassium phosphate is useful as a preservative and a flavor enhancer, among other things.
This artificial type of salt is made from the elements potassium and phosphorus.
Chemists create it in a lab.
Some foods like legumes and wheat products naturally have similar phosphates.
Processed foods usually have much higher levels ofDipotassium phosphate as an additive.
Dipotassium phosphate falls into the larger category of sodium phosphates that are used in consumer products.
Dipotassium phosphate looks like a white, grainy powder.



DIPOTASSIUM PHOSPHATE IN FOOD:
Dipotassium phosphate is very common in processed and packaged foods.
Some of the purposes Dipotassium phosphate serves in the manufacturing process are:

*Emulsifier:
Dipotassium phosphate is a chemical that helps to bind fats and water together.
Fats don’t mix with many other liquids without help.
Think about oil and vinegar.
Emulsifiers have a chemical structure that helps them mix.
Dipotassium phosphate is a helpful emulsifier for dairy products and other foods.
Cheese, whipped cream, milk, and other dairy products have unique textures and consistencies because of disodium phosphate.

*Preservative:
Dipotassium phosphate is also helpful in canning food since it prevents metal from rusting.

*Flavor enhancer:
Processed foods often have additives that strengthen their flavor and make them more savory.
Many foods have potassium-containing additives to enhance their flavor.

*pH control:
A food’s pH level (or level of acidity) can affect its nutritional value, color, and other characteristics.
Canning or using jars can alter foods’ pH levels.
Dipotassium phosphate can help control a food’s pH level throughout the production process.



PHARMACODYNAMICS of DIPOTASSIUM PHOSPHATE:
Phosphate is a major intracellular anion which participates in providing energy for metabolism of substances and contributes to important metabolic and enzymatic reactions in almost all organs and tissues.
Phosphate exerts a modifying influence on calcium concentrations, a buffering effect on acid-base equilibrium, and has a major role in the renal excretion of hydrogen ions.



MECHANISM of ACTION of DIPOTASSIUM PHOSPHATE:
Once phosphate gains access to the body fluids and tissues, it exerts little pharmacological effect.
If the ion is introduced into the intestine, the absorbed phosphate is rapidly excreted.
If large amounts are given by this route, much of it may escape absorption.
Because this property leads to a cathartic action, phosphate salts are employed as mild laxatives.



ABSORPTION of DIPOTASSIUM PHOSPHATE:
Potassium salts are well absorbed from gastro intestinal tract.
Net phosphorus absorption may occur in the small intestine in some species but is primarily a function of the colon in horses.



VOLUME of DISTRIBUTION of DIPOTASSIUM PHOSPHATE:
Distribution is largely intracellular, but it is the intravascular concentration that is primarily responsible for toxicity.



PROTEIN BINDING of DIPOTASSIUM PHOSPHATE:
Phosphate is minimally protein bound, and highly concentrated in cells (intracellular concentrations are 100-fold higher than serum concentrations).
Concentrations of phosphate in plasma are higher in children than in adults.



METABOLISM of DIPOTASSIUM PHOSPHATE:
Phosphate is a major intracellular anion which participates in providing energy for metabolism of substances and contributes to important metabolic and enzymatic reactions in almost all organs and tissues.



CHARACTERISTICS of DIPOTASSIUM PHOSPHATE:
The IUPAC name of Dipotassium phosphate is dipotassium hydrogen phosphate.
The density of Dipotassium Phosphate is 2.44g/cm3
The K2HPO4 molecular weight or molar mass is 174.2g/mol
Dipotassium phosphate accepts four hydrogen bonds
The melting point of Dipotassium phosphate is greater than 465 °C
The chemical formula of Dipotassium phosphate is K2HPO4
Dipotassium phosphate is freely soluble in water
Dipotassium phosphate is insoluble in ethanol
The production of Dipotassium phosphate is done in the process of condensation of phosphoric acid using potassium hydroxide
As a result, Phosphoric acid is manufactured from the rock of phosphate, which is found commonly in several places around the globe.



PHYSICAL PROPERTIES of DIPOTASSIUM PHOSPHATE:
The Dipotassium Phosphate compound is odourless
The colour of Dipotassium phosphate is white
Dipotassium phosphate is a deliquescent solid which means that it tends to absorb moisture from the air and dissolve in it
Dipotassium phosphate is a three covalently bonded unit
The molecule of Dipotassium phosphate has a heavy atom count of 7
The complexity of Dipotassium phosphate is 4605
Dipotassium phosphate can be easily soluble in water



CHEMICAL PROPERTIES of DIPOTASSIUM PHOSPHATE:
Reaction with hydrochloric acid (HCL)
The compound Dipotassium Phosphate when reacts with hydrochloric acid, it forms potassium chloride and phosphoric acid.
The chemical equation of the reaction is given below: -
K2HPO4 + 2HCl → 2KCl + H3PO4
Reaction with sodium hydroxide (NaOH)
The compound dipotassium hydrogen phosphate when reacts with a base, sodium hydroxide it forms disodium hydrogen phosphate and water.
2NaOH + 3K2HPO4 → 2K3PO4 + 2H2O + Na2HPO4

Dipotassium Phosphate reacts with hydrogen chloride forms phosphoric acid and potassium chloride.
The chemical equation is given below.
K2HPO4 + 2HCl → 2KCl + H3PO4
Dipotassium Phosphate reacts with a base like sodium hydroxide forms disodium hydrogen phosphate and water.
3K2HPO4 + 2NaOH → Na2HPO4 + 2K3PO4 + 2H2O



BENEFITS of DIPOTASSIUM PHOSPHATE:
Liquid solution is easily stored and pumped
Labor and time are saved compared to dissolving dry ingredients
Liquid solution is more economical compared to the dry form
Sustainable product with a low carbon footprint through reduced energy consumption and packaging waste

Dipotassium phosphate is a great source of potassium, essential for contributing to normal muscle function.
Dipotassium phosphate also supports the recovery of muscles, making it ideal for endurance athletes.
At a quick glance, the primary benefit of dipotassium phosphate is that it is a convenient source of potassium, which contributes to your normal muscle function.
For weightlifters, bodybuilders and athletes, dipotassium phosphate supplements may be useful for several reasons.

-May increase energy in workouts :
Firstly, Dipotassium phosphate can be used in energy supplements for workouts requiring prolonged periods of work without rest, such as long-distance running, team sports, high-intensity interval training and endurance-style weightlifting sessions.
Dipotassium phosphate does this by supporting the recovery of your muscles, which means a better recovery rate and the ability to get in more lifts.
To summarise, dipotassium phosphate improves endurance by increasing your body’s efficiency in transporting oxygen to your muscles, thus helping energy production.
This is particularly effective for high intensity and particularly strenuous exercises such as heavy lifting and sprints.

-Helps increase your intake of potassium :
Potassium is one of the seven essential macro minerals, of which your body requires at least 100 milligrams on a daily basis in order to sufficiently support its key processes.
Whilst it’s possible to hit your requirements from dietary sources such as fruits, vegetables, fish and meat, supplementing potassium can help increase your daily intake.
A healthy intake of potassium decreases your risk of stroke, lowers your blood pressure, protects you against the loss of muscle mass, preserves your bone mineral density, and reduces the risk of kidney stones.



WHAT ARE PHOSPHATES?
Phosphates are a group of inorganic chemicals that are obtained through the neutralization of phosphoric acid which results in the substitution of a hydrogen cation and produces a salt.
There are several varieties of phosphate salts, depending on the reaction source, such as potassium hydroxide being used to create a potassium phosphate.



HOW IS DIPOTASSIUM PHOSPHATE MADE?
Dipotassium Phosphate (DKP) has been used in food production for decades and is made by reacting a source of potassium (usually potassium hydroxide) with phosphoric acid.
Food-grade phosphoric acid is made from phosphate rocks, which are mined, refined and purified.
Companies that make phosphoric acid in the U.S., Europe and elsewhere follow strict procedures to ensure purity.
The phosphoric acid is reacted with potassium hydroxide and lime water to form a wet mix.
The resulting reaction creates potassium phosphate, which is then dried and crystalized.
Finally the product is sized down to specifications.
Food grade phosphates that are manufactured in the United States comply with the new regulations for food safety as set forth in the Food Safety Modernization Act.



WHY ARE PHOSPHATES IN MY FOOD?
Dipotassium Phosphate has many uses in food.
Dipotassium Phosphate has the ability to act as an emulsifier, protein stabilizer and buffering agent.
In addition Dipotassium Phosphate can provide a source of Potassium for many foods that otherwise would not have that.
Some common uses are as follows:

*Coffee Creamers:
Dipotassium Phosphate can help stabilize the protein layer around fat droplets present in the milk, which helps prevent syneresis and curdling when added to a hot beverage.

*Processed cheese products:
Dipotassium Phosphate help buffer the pH and interact with the milk proteins to promote emulsification.

*Nutrient resource:
Dipotassium Phosphate can be used as a mineral supplement for pharmaceuticals and a nutrient base during yeast production and other fermentation processes.

*Soy protein based beverages:
Dipotassium Phosphate can help stabilize soy proteins and act as a dispersing agent.
Dipotassium Phosphate is a multi-purpose food additive.
Not only does this allow for certain foods to be shelf-stable and appealing but you get the added benefit of potassium.
Without Dipotassium Phosphate many dairy based coffee creamers, cheese products and any other food that is lacking in potassium would not be possible without the use of other, possibly more expensive, ingredients that do not have the additional benefit of potassium.



MANUFACTURING PROCESS of DIPOTASSIUM PHOSPHATE:
Dipotassium phosphate is produced by the stoichiometric reaction of phosphoric acid with two equivalents of potassium hydroxide.
This neutralization reaction produces the aqueous salt of dipotassium phosphate and water.
Water is then removed to obtain the fine white powder of potassium hydrogen phosphate.
By controlling the amount of potassium hydroxide added, potassium dihydrogen phosphate and tripotassium phosphate can be produced.



PHYSICAL and CHEMICAL PROPERTIES of DIPOTASSIUM PHOSPHATE:
Molar mass: 174.2 g/mol
Appearance: white powder
Odor: odorless
Density: 2.44 g/cm3
Melting point: > 465 °C (869 °F; 738 K) decomposes
Solubility in water: 149.25 g/100 mL (20 °C)
Solubility: slightly soluble in alcohol
Acidity (pKa): 12.4
Basicity (pKb): 6.8
Solubility: Clear
Purity: 99%
Storage: Keep away from moisture
Other Names: Di Potassium Phosphate
Classification: Inorganic Chemicals
Chemical Name: Di Potassium Phosphate

Molecular Weight: 174.176
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 173.88865848
Monoisotopic Mass: 173.88865848
Topological Polar Surface Area: 83.4 Ų
Heavy Atom Count: 7
Formal Charge: 0
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Appearance Form: solid
Color: white
Odor: odorless
Odor: Threshold Not applicable
pH: 9,2weakly alkaline
Melting point/range: > 450 °C
Initial boiling point and boiling range: No data available
Flash point: Not applicable
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: 2,45 at 20,5 °C
Water solubility at 20 °C: completely soluble
Partition coefficient: n-octanol/water: Not applicable for inorganic substances

Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Chemical Name: Potassium hydrogen phosphate
Grade: Extra pure
Cas No: 7758-11-4
EC Number: 231-834-5
Hill Formula: HK₂O₄P
Chemical Formula: K₂HPO₄
Molar Mass: 174.18 g/mol
HS Code: 2835.24.00
Assay (acidimetric): 98,0 - 101,0 %
Chloride ( as Cl): <= 0,005 %

Sulfate (SO4): <= 0,02 %
Iron(Fe): <= 0,002 %
Heavy Metals (as Pb): <= 0,001 %
Sodium (Na): <= 1,0 %
pH (5 %, H2O 25°C): 8,5 - 9,5
Loss on drying: <= 2,0 %
Molecular Weight: 174.18
Molecular Formula: K2HPO4
Appearance: White Fine Powder
PH Range (5 % w/v): 8.5 to 9.6
Assay % / Purity % (minimum): 98.00
P2O5 Content % (minimum): 40.00
‘K’ Content %: 44.78
Iron as ‘Fe’ Content: %0.02
Chloride as ‘Cl’ content: %0.2
Sulfate as ‘SO4’ content: %0.03



FIRST AID MEASURES of DIPOTASSIUM PHOSPHATE:
-After inhalation:
Fresh air.
-In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
-After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
-After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.



ACCIDENTAL RELEASE MEASURES of DIPOTASSIUM PHOSPHATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of DIPOTASSIUM PHOSPHATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of DIPOTASSIUM PHOSPHATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of DIPOTASSIUM PHOSPHATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
hygroscopic
-Specific end use(s):
No other specific uses are stipulated



STABILITY and REACTIVITY of DIPOTASSIUM PHOSPHATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
Potassium monohydrogen phosphate
Phosphoric acid dipotassium salt
Potassium phosphate dibasic
Dipotassium hydrogen phosphate
7758-11-4
DIPOTASSIUM PHOSPHATE
Potassium phosphate dibasic
Dipotassium hydrogenphosphate
Dibasic potassium phosphate
Potassium Hydrogen Phosphate
Potassium phosphate, dibasic
Phosphoric acid, dipotassium salt
Potassium dibasic phosphate
Dipotassium monophosphate
Potassium monohydrogen phosphate
K2HPO4
Potassium monophosphate
Dipotassium hydrogenorthophosphate
Dipotassium monohydrogen phosphate
Dipotassium orthophosphate
MFCD00011383
Hydrogen dipotassium phosphate
Potassium phosphate (dibasic)
di-potassium hydrogen phosphate
Dipotassium hydrogen orthophosphate
sec.-Potassium phosphate
Dipotassium acid phosphate
potassium hydrogenphosphate
Phosphoric acid, potassium salt (1:2)
Secondary potassium phosphate
CI71S98N1Z
INS NO.340(II)
INS-340(II)
Dipotassium hydrogen monophosphate
E-340(II)
Potassium phosphate dibasic, ACS reagent
Isolyte
Dipotassium-O-phosphate
dipotassium;hydrogen phosphate
CCRIS 6544
HSDB 935
Kali phosphoricum
Leex-A-phos
EINECS 231-834-5
Mediject P (TN)
di potassium phosphate
PotassiumHydrogenPhosphate
Potassium phosphate,dibasic
dipotasium hydrogen phosphate
UNII-CI71S98N1Z
potassium monohydrogenphosphate
potassium hydrogen monophosphate
CHEMBL1200459
DTXSID8035506
KALI PHOSPHORICUM [HPUS]
CHEBI:32031
CHEBI:131527
DIPOTASSIUM PHOSPHATE
dipotassium monohydrogen orthophosphate
potassium dibasic phosphate trihydrate
POTASSIUM PHOSPHATE (K2HPO4)
AKOS015915872
AKOS016371887
DB09414
Potassium hydrogen phosphate, anhydrous
POTASSIUM PHOSPHATE
Potassium Phosphate, Dibasic, Anhydrous
Potassium phosphate dibasic, USP reagent
Potassium phosphate, dibasic
Potassium phosphate, dibasic
Potassium phosphate dibasic, LR, >=98%
SY010082
DI-POTASSIUM HYDROGEN ORTHOPHOSPHATE
DIPOTASSIUM PHOSPHATE
POTASSIUM PHOSPHATE, DIBASIC
POTASSIUM PHOSPHATE, DIBASIC
POTASSIUM PHOSPHATE,DIBASIC
DIPOTASSIUM PHOSPHATE
POTASSIUM PHOSPHATE DIBASIC ANHYDRATE
POTASSIUM PHOSPHATE, DIBASIC
DIBASIC POTASSIUM PHOSPHATE
POTASSIUM PHOSPHATE DIBASIC
Potassium phosphate dibasic solution, 1.0 M
Potassium phosphate dibasic, Biochemical grade
Potassium phosphate dibasic, puriss., >=99%
D02403
DIPOTASSIUM HYDROGEN PHOSPHATE (K2HPO4)
EC 231-834-5
DIBASIC POTASSIUM PHOSPHATE [USP IMPURITY]
DIBASIC POTASSIUM PHOSPHATE [USP MONOGRAPH]
Potassium phosphate dibasic, ACS reagent, >=98%
Potassium phosphate dibasic, USP, 98.0-100.5%
POTASSIUM PHOSPHATE, DIBASIC [ORANGE BOOK]
Q403721
Potassium phosphate dibasic, AR, anhydrous, >=99%
POTASSIUM PHOSPHATE, DIBASIC [USP IMPURITY]
Potassium phosphate dibasic, reagent grade, >=98.0%
Potassium phosphate dibasic, 99.95% trace metals basis
Potassium phosphate dibasic, SAJ first grade, >=98.0%
Potassium phosphate dibasic, Trace metals grade 99.95%
Potassium phosphate dibasic, JIS special grade, >=99.0%
Potassium phosphate dibasic, Vetec(TM) reagent grade, 98%
Potassium phosphate dibasic, meets USP testing specifications
DIBASIC POTASSIUM PHOSPHATE COMPONENT OF POTASSIUM PHOSPHATES
POTASSIUM PHOSPHATES COMPONENT DIBASIC POTASSIUM PHOSPHATE
Dibasic potassium phosphate, United States Pharmacopeia (USP) Reference Standard
Potassium phosphate dibasic, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=98%
Potassium phosphate dibasic, puriss. p.a., ACS reagent, anhydrous, >=99.0% (T)
Potassium phosphate dibasic, anhydrous, for luminescence, for molecular biology, BioUltra, >=99.0% (T)
Phosphoric Acid Dipotassium Salt
Conclyte P
DKP
Dibasic Potassium Phosphate
Dipotassium Hydrogen Orthophosphate
Dipotassium Hydrogen Phosphate
Dipotassium Hydrogen Phosphate (K2HPO4)
Dipotassium Monohydrogen Phosphate
Dipotassium Monophosphate
Dipotassium Orthophosphate
Dipotassium Phosphate
Dipotassium Phosphate (K2HPO4)
Hydrogen Dipotassium Phosphate
Potassium Biphosphate
Potassium Dibasic Phosphate (K2HPO4)
Potassium Hydrogen Phosphate (K2HPO4)
Potassium Monoacid Phosphate
Potassium Monohydrogen Phosphate
Potassium Monophosphate
Potassium Phosphate (K2HPO4)
Potassium Phosphate Dibasic
Rhodiaphos DKP
dipotassium hydrogen orthophosphate
dipotassium hydrogen phosphate
dipotassium hydrogenorthophosphate
dipotassium hydrogenphosphate
dipotassium monohydrogen phosphate
dipotassium-O-phosphate
hydrogen dipotassium phosphate
phosphoric acid dipotassium salt
phosphoric acid, dipotassium salt
potassium dibasic phosphate
potassium hydrogen phosphate
potassium hydrogen phosphate (2:1:1)
potassium phosphate (dibasic)
potassium phosphate dibasic
potassium phosphate, dibasic
Di-potassium monohydrogen phosphate
231-834-5 [EINECS]
7758-11-4
CI71S98N1Z
Dibasic potassium phosphate
Dipotassium hydrogen phosphate
Dipotassium hydrogenphosphate
DIPOTASSIUM PHOSPHATE
MFCD00011383 [MDL number]
phosphate dipotassium
Potassium hydrogen phosphate (2:1:1)
Potassium phosphate dibasic
Potassium phosphate dibasic anhydrous
sec.-Potassium phosphate
[7758-11-4]
04/11/7758
16068-46-5
22116-90-1
60704-91-8
Dipotassium acid phosphate
Dipotassium hydrogen monophosphate
DIPOTASSIUM HYDROGEN ORTHOPHOSPHATE
DI-POTASSIUM HYDROGEN ORTHOPHOSPHATE
di-Potassium hydrogen phoshpate anhydrous
Di-potassium hydrogen phosphate
di-Potassium hydrogen phosphate, anhydrous
Dipotassium hydrogen phosphate
Potassium phosphate dibasic
Di-potassium hydrogen phosphate
Dibasic potassium phosphate
Dipotassium acid phosphate
Dipotassium hydrogen monophosphate
Dipotassium hydrogen orthophosphate
Dipotassium hydrogen phosphate
Dipotassium monophosphate
Kali phosphoricum
Phosphoric acid, dipotassium salt
Phosphoric acid, potassium salt (1:2)
Potassium phosphate dibasic
Potassium phosphate, dibasic
Potassium phosphate,dibasic
Secondary potassium phosphate
Dipotassium hydrogenorthophosphate
Dipotassium monohydrogen phosphate
Dipotassium monophosphate
Dipotassium orthophosphate
di-potassium phosphate
dipotassium;hydrogen phosphate
Dipotassium-O-phosphate
Dipotassium-Phosphate
DKP
EINECS 231-834-5
Hydrogen dipotassium phosphate
Isolyte
K2HPO4
Kali phosphoricum
Mediject P (TN)
Neutra-Phos
Phosphoric Acid Dipotassium
Phosphoric acid dipotassium salt
Phosphoric acid, dipotassium salt
Phosphoric acid, potassium salt (1:2)
Phosphoric acid-d,dipotassium salt (8CI,9CI)
POTASSIUM BIPHOSPHATE
Potassium dibasic phosphate
potassium hydrogen phosphate
Potassium Hydrogen Phosphate (reagent)
Potassium Hydrogen Phosphate, Dipotassium Phosphate
potassium hydrogenphosphate
POTASSIUM MONOHYDROGEN PHOSPHATE
Potassium monophosphate
Potassium phosphate (dibasic)
Potassium phosphate dibasic, ACS reagent
Potassium phosphate dibasicmissing
Potassium Phosphate, Dibasic
Potassium Phosphate, Dibasic, Anhydrous
Potassium phosphate, dibasic, anhydrous
Potassium phosphate,dibasic
Secondary potassium phosphate
UNII:CI71S98N1Z
UNII-CI71S98N1Z



DIPROPYLAMINE
CAS Number: 142-84-7
EC Number: 205-565-9
Preferred IUPAC name: N-Propylpropan-1-amine
Molecular Formula: C6H15N

DESCRIPTION:

Dipropylamine is a flammable, highly toxic, corrosive amine.
Dipropylamine occurs naturally in tobacco leaves and artificially in industrial wastes.
Exposure can cause excitement followed by depression, internal bleeding, dystrophy, and severe irritation

Dipropylamine appears as a clear colorless liquid with an ammonia-like odor.
Dipropylamine has Flash point of 30 °F.
Dipropylamine is Less dense than water.
Vapors of Dipropylamine are heavier than air.
Toxic oxides of nitrogen produced during combustion.


Dipropylamine (DPA; also called Di-N-Propylamine DNPA) is a secondary amine which belongs to the class of dialkylamines.
Dipropylamine is a versatile intermediate with a variety of applications.

Dipropylamine is a chemical compound that belongs to the group of amines.
Dipropylamine has inhibitory properties against prostate cancer cells and fatty acid, hydroxyl group, amines and trifluoroacetic acid.
Dipropylamine can be used for the prevention of prostate cancer by inhibiting the production of fatty acids, which are necessary for lipid synthesis in cells.

This dru Dipropylamine may also help reduce the spread of prostate cancer cells by preventing their growth and division.
In addition, dipropylamine is able to inhibit the enzyme fatty acid synthase that catalyzes the production of these lipids in cells.

Dipropylamine is a member of the class of compounds known as dialkylamines.
Dialkylamines are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen.
Dipropylamine is soluble (in water) and a very strong basic compound (based on its pKa).
Dipropylamine can be found in a number of food items such as wild celery, orange bell pepper, yellow bell pepper, and pepper (c. annuum), which makes di-n-propylamine a potential biomarker for the consumption of these food products.


PRODUCTION METHOD OF DIPROPYLAMINE:
1.The n-propanol ammonification method uses propanol as raw material and is obtained by catalytic dehydrogenation, ammonification, dehydration and hydrogenation (see "Tripropylamine") .
According to relevant data reports, if nickel-copper-pumice is used as the catalyst for the above reaction, it is beneficial to the formation of dipropylamine; nickel-copper-activated alumina is used as the catalyst, it is beneficial to the production of tripropylamine.
2. Acrylonitrile hydrogenation method uses acrylonitrile as raw material and copper-nickel compounds as catalyst to produce dipropylamine by catalytic hydrogenation at 40-250 ℃ and 0-4.9MPa.
In addition, the hydrogenation of propiononitrile or acrylonitrile, when using a carbon-supported rhodium catalyst, using excess hydrogen to continuously remove ammonia, the selectivity of dipropylamine is above 85%, and n-propylamine is rarely generated, and tripropylamine is not generated at all.

The reduction amination of propionaldehyde under the action of rhodium catalyst also obtains a high proportion of dipropylamine.
Preparation method of dipropylamine is based on propanol as raw material, through catalytic dehydrogenation, ammoniation, dehydration, hydrogenation.
The reaction catalyst is Ni-Cu-Al2O3, the pressure is (39±1)kPa, the reactor temperature is (190±10)℃, the space velocity of propanol is 0.05~0.15 h-1, the raw material ratio is propanol: ammonia: hydrogen = 4:2:4, and dipropylamine and tripropylamine are obtained at the same time.

CAS Number: 142-84-7
EC Number: 205-565-9
Preferred IUPAC name: N-Propylpropan-1-amine
Molecular Formula: C6H15N

USES OF DIPROPYLAMINE :
Dipropylamine is a raw material for organic synthesis, which is used to produce pesticide herbicides such as trifluralin, duleling, mash-killing and Dada-killing, dipropylglutamine and other medicines, and is also used as a boiler preservative, engine coolant, carbon removal agent, anti-corrosion lubricant and emulsifier and solvent, etc.
Dipropylamine can be used as a solvent and as an intermediate for the production of medicines, pesticides, dyes, mineral flotation agents, emulsifiers and fine chemicals.
Dipropylamine is used in the preparation of pesticides, medicines, emulsifiers, etc.
Dipropylamine is the herbicide trifluralin and sulfuryl, grass grass Dan, grass grass enemy intermediates.
Dipropylamine is Used for the preparation of pesticides, pharmaceuticals (dipropylglutamide, etc.), boiler preservatives, engine coolants, lubricants, metal cutting oils, decarbonizers, anti-corrosion lubricants and emulsifiers, and solvents.
Among them, pesticides are the most important use.
The main pesticides produced by dipropylamine: trifluralin, diuralin, mikaomeng, gerondamine, methyl sulfone, isopyrene, jialeling, mikao Dan, bikao Dan.
Solvents, and intermediates used in the production of medicines, pesticides, dyes, mineral flotation agents, emulsifiers, and fine chemicals.

CHEMICAL AND PHYSICAL PROPERTIES OF DIPROPYLAMINE:
Chemical formula: C6H15N
Molar mass: 101.193 g•mol−1
Appearance: Colorless liquid
Odor: Ichtyal, ammoniacal
Density : 738 mg mL−1
Melting point: −63.00 °C; −81.40 °F; 210.15 K
Boiling point: 109 to 111 °C; 228 to 232 °F; 382 to 384 K
Solubility in diethyl ether: Miscible
Henry's law constant (kH): 190 μmol Pa−1 kg−1
Refractive index (nD): 1.4049
Std enthalpy of formation (ΔfH⦵298): −156.1–−153.1 kJ mol−1
Std enthalpy ofcombustion (ΔcH⦵298): −4.3515–−4.3489 MJ mol−1
Molecular Weight: 101.19
XLogP3: 1.7
Boiling point: 105 °C (1013 hPa)
Density : 0.738 g/cm3
Explosion limit: 1.8 - 9.3 %(V)
Flash point: 7 °C
Ignition temperature: 260 °C
Melting Point: -40 °C
Vapor pressure: 26.8 hPa (25 °C)
Solubility: 35 g/l (experimental)
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 4
Exact Mass: 101.120449483
Monoisotopic Mass: 101.120449483
Topological Polar Surface Area: 12 Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 23.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Assay: 99%
Form:liquid
Refractive index:n20/D 1.4049 (lit.)
Bp:105-110 °C (lit.)
Density:0.738 g/mL at 25 °C (lit.)
Melting point: -63 °C
Boiling point: 105-110 °C(lit.)
Density: 0.738 g/mL at 25 °C(lit.)
vapor pressure: 38 hPa (20 °C)
refractive index : n20/D 1.4049(lit.)
Flash point: 39 °F
storage temp.: Store below +30°C.
solubility: 35g/l (experimental)
form: Liquid
pka: pK1:10.91(+1) (25°C)
color: Clear
explosive limit: 1.8-9.3%(V)
Water Solubility: soluble
Merck: 14,3343
BRN: 505974
Stability: Stable. Highly flammable. Incompatible with strong oxidizing agents.
LogP: 1.33 at 23℃
Dissociation constant: 11
Water Solubility: 44.4 g/L
logP: 1.74
logP: 1.57
logS: -0.36
pKa (Strongest Basic): 10.77
Physiological Charge: 1
Hydrogen Acceptor Count: 1
Hydrogen Donor Count: 1
Polar Surface Area: 12.03 Ų
Rotatable Bond Count: 4
Refractivity: 33.24 m³•mol⁻¹
Polarizability: 13.78 ų
Number of Rings: 0
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule: No
Vapour Pressure (Pa) : 4212 [Pa] at a temperature of 20°C
Ignition Temperature (°C): 316
Lower explosivity limit (LEL) (volume %) : 1.8
Upper explosivity limit (UEL) (volume %): 9.3

REACTIVITY DATA OF DIPROPYLAMINE:
Water: No
Acid(s): Yes
Base(s): No
Metal(s) and alloys: No
Oxidizing agents: Yes
Reducing agents: No
Combustibles: No
Organic substance: Yes

CAS Number: 142-84-7
EC Number: 205-565-9
Preferred IUPAC name: N-Propylpropan-1-amine
Molecular Formula: C6H15N


SAFETY INFORMATION ABOUT DIPROPYLAMINE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.


CAS Number: 142-84-7
EC Number: 205-565-9
Preferred IUPAC name: N-Propylpropan-1-amine
Molecular Formula: C6H15N

SYNONYMS OF DIPROPYLAMINE:
DIPROPYLAMINE
142-84-7
Di-n-propylamine
1-Propanamine, N-propyl-
n-Dipropylamine
N-propylpropan-1-amine
N-Propyl-1-propanamine
RCRA waste number U110
di(n-propyl)amine
DIPROPYL-AMINE
di-n-propylamin
60P318IIRY
dipropyl amine
RCRA waste no. U110
CCRIS 4805
HSDB 2644
EINECS 205-565-9
UN2383
BRN 0505974
UNII-60P318IIRY
di-propylamine
AI3-24037
di-n-propyl amine
N,N-Dipropylamine
N-propyl propylamine
N-propyl-propylamine
MFCD00009362
Dipropylamine, 99%
N,N-Dipropylamine #
N,N-di-n-propylamine
DSSTox_CID_5185
DiPropylamine Reagent Grade
EC 205-565-9
DIPROPYLAMINE [HSDB]
DSSTox_RID_77699
DSSTox_GSID_25185
SCHEMBL15445
N-DIPROPYLAMINE [MI]
(n-C3H7)2NH
CHEMBL3185961
DTXSID2025185
STR03559
ZINC1672989
Tox21_202085
BBL027756
STL194269
AKOS000118843
UN 2383
NCGC00249163-01
NCGC00259634-01
CAS-142-84-7
D0930
FT-0614098
FT-0625300
Dipropylamine [UN2383] [Flammable liquid]
EN300-19590
Q410621
J-007705
J-520390
F2190-0303
DPA
DI-N-PROPYLAMINE
DNPA
n,n-dipropylamine
ai3-24037
(n-C3H7)2NH
Di-n-propyL
DIPROPYLAMINE
Dipropanamine
AURORA KA-7671
142-84-7 [RN]
1-Propanamine, N-propyl- [ACD/Index Name]
205-565-9 [EINECS]
DI-N-PROPYLAMINE
Dipropylamine [Wiki]
Dipropyl-amine
JL9200000
MFCD00009362 [MDL number]
n-Dipropylamine
n-propyl-1-propanamin [ACD/IUPAC Name]
N-Propyl-1-propanamin [German] [ACD/IUPAC Name]
N-Propyl-1-propanamine [ACD/IUPAC Name]
N-Propyl-1-propanamine [French] [ACD/IUPAC Name]
N-Propylpropan-1-amine
(n-C3H7)2NH [Formula]
3,3'-IMINODIPROPIONITRILE
345909-05-9 [RN]
63220-61-1 [RN]
92517-02-7 [RN]
DI(N-PROPYL)AMINE
DI(PROPYL-3,3,3-D3)AMINE
DI-N-PROPYL-1,1,2,2,3,3,3-D7-AMINE (MONO-PROPYL-D7)
Di-n-propylamin
Di-n-propyl-d14-amine
dipropilamina [Portuguese]
dipropyl amine
dipropylammonium
EINECS 205-565-9
N,N-dipropylamine
N-Propyl-propylamine
STR03559
UN 2383


DIPROPYLAMINE
CAS number: 142-84-7
EC Number: 205-565-9
Chemical formula: C6H15N
Molar mass: 101.193 g·mol−1
IUPAC Name: N-propylpropan-1-amine

Dipropylamine is a flammable, highly toxic, corrosive amine.
Dipropylamine occurs naturally in tobacco leaves and artificially in industrial wastes.
Dipropylamine exposure can cause excitement followed by depression, internal bleeding, dystrophy, and severe irritation.

Dipropylamine (DPA; also called Di-N-Propylamine DNPA) is a secondary amine which belongs to the class of dialkylamines.
Dipropylamine is a versatile intermediate with a variety of applications.

Chemical Properties of Dipropylamine:
Dipropylamine is a colourless liquid.

Chemical Properties of Dipropylamine:
Dipropylamine, like the other short chain aliphatic amines, is a very strong base, its reactivity being governed by the unshared electron pair on the nitrogen atom.
Dipropylamine forms a hydrate with water.
The amine also can react with inorganic or organic nitrites under acidic conditions and possibly by reaction with nitrogen oxides from the air to form the highly mutagenic and carcinogenic N-nitrosodipropylamine.

Production Methods of Dipropylamine:
Dipropylamine is manufactured by reaction of propanol and ammonia over a dehydration catalyst at high temperature and pressure.
Alternatively, propanol and ammonia can be combined with hydrogen over a dehydrogenation catalyst.
In each instance, the resulting mixture of primary, secondary, and tertiary amines can be separated by continuous distillation and extraction.
Dipropylamine is a natural component of vegetables, fish, fruits, and other foods and of tobacco products.

Dipropylamine also is found in human urine, waste water lagoons and in workplace air.
The toxic compound, Dipropylamine, can be produced inadvertently by nitrosation of n-dipropylamine during various manufacturing processes that use the diamine.
Dipropylamine, therefore, occurs as an impurity in some dinitroaniline pesticides and rubber products.
Dipropylamine also is found in various foodstuffs including cheese, cured meats, cooked fish and alcoholic beverages, apparently by reaction of n-dipropylamine with the preservative sodium nitrite.

General Description of Dipropylamine:
Dipropylamine is a clear colorless liquid with an ammonia-like odor.
Dipropylamine' flash point is 30°F.
Dipropylamine is less dense than water.
Dipropylamine vapors heavier than air.
Toxic oxides of nitrogen produced during combustion.

Applications, intermediate used in the production of: crop protection agents, herbicides, pharmaceuticals. Packaging, available in bulk and drums.

Air & Water Reactions of Dipropylamine:
Dipropylamine is highly flammable.
Dipropylamine is soluble in water.

Product Description:
General:
Synonyms: di-n-propylamine, N,N-dipropylamine, N-propyl-1-
propanamine, N-dipropylamine
Use: synthetic intermediate
Molecular formula: C6H15N
CAS No: 142-84-7
EINECS No: 205-565-9
Annex I Index no: 612-048-00-5

Dipropylamine is used in the rubber industry and as a chemical intermediate in themanufacture of the herbicides S-ethyl-di-n-propylthiocarbamate and S-propyldi-n-propylthiocarbamate.
Dipropylamine also is employed in thepurification of perfluoro compounds to convert the incompletely fluorinatedimpurities to solids which are then removed by filtration.

Description of Dipropylamine:
Dipropylamine is a flammable, highly toxic, corrosive amine.
Dipropylamine occurs naturally in tobacco leaves and artificially in industrial wastes.
Exposure can cause excitement followed by depression, internal bleeding, dystrophy, and severe irritation.

Chemical Name: Dipropylamine
Synonyms: DPA;DNPA;ai3-24037;(n-C3H7)2NH;Di-n-propyL;DIPROPYLAMINE;Dipropanamine;AURORA KA-7671;N-Dipropylamine;Di-n-propylamin
CBNumber: CB1713802
Molecular Formula: C6H15N

IDENTIFICATION of Dipropylamine:
Dipropylamine is a colorless liquid with a strong ammonialike odor.
Dipropylamine is used as a chemical intermediate in the manufacture of herbicides.

Physical data:
Appearance: colorless liquid
Melting point: -40 C
Boiling point: 108 - 110 C
Vapor density:
Vapor pressure:
Density (g cm-3): 0.74
Flash point: 7 C (closed cup)
Explosion limits:
Autoignition temperature:
Water solubility: soluble, forming hydrates
Stability: Stable
Highly flammable. Incompatible with strong oxidizing agents.

Reactivity Profile of Dipropylamine:
Dipropylamine neutralizes acids in exothermic reactions to form salts plus water.
Dipropylamine may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard of Dipropylamine:
Dipropylamine inhalation causes severe coughing and chest pain due to irritation of air passages; can-cause lung edema; may also cause headache, nausea, faintness, and anxiety.
Dipropylamine ingestion causes irritation and burning of mouth and stomach.
Dipropylamine contact with eyes causes severe irritation and edema of the cornea.
Dipropylamine contact with skin causes severe irritation.

Health Hazard of Dipropylamine:
Inhalation of dipropylamine vapors can result in severe coughing and chest pain due to irritation of airways.
Transient symptoms of exposure may include headache, nausea, faintness, and anxiety.
Prolonged breathing of vapors may result in lung edema.
Dipropylamine also can cause severe irritation and edema of the cornea.
A review of the toxicity of dipropylamine has been prepared.

Fire Hazard of Dipropylamine:
Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fires.

Preferred IUPAC name:
N-Propylpropan-1-amine

CAS Number: 142-84-7
Beilstein Reference: 505974
ChemSpider: 8562
ECHA InfoCard: 100.005.060
EC Number: 205-565-9
PubChem CID: 8902
RTECS number: JL9200000
UNII: 60P318IIRY
UN number: 2383
CompTox Dashboard (EPA): DTXSID2025185

The 2D chemical structure image of DIPROPYLAMINE is also called skeletal formula, which is the standard notation for organic molecules.
The carbon atoms in the chemical structure of DIPROPYLAMINE are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated – each carbon atom is considered to be associated with enough hydrogen atoms to provide the carbon atom with four bonds.

The 3D chemical structure image of DIPROPYLAMINE is based on the ball-and-stick model which displays both the three-dimensional position of the atoms and the bonds between them.
The radius of the spheres is therefore smaller than the rod lengths in order to provide a clearer view of the atoms and bonds throughout the chemical structure model of DIPROPYLAMINE.

Chemical formula: C6H15N
Molar mass: 101.193 g·mol−1
Appearance : Colorless liquid
Odor: Ichtyal, ammoniacal
Density: 738 mg mL−1
Melting point: −63.00 °C; −81.40 °F; 210.15 K
Boiling point: 109 to 111 °C; 228 to 232 °F; 382 to 384 K
Solubility in diethyl ether: Miscible
Henry's law constant (kH): 190 μmol Pa−1 kg−1
Refractive index (nD): 1.4049

Other names:
(Dipropyl)amine

Industrial uses of Dipropylamine:
Dipropylamine is used in the rubber industry and as a chemical intermediate in the manufacture of the herbicides S-ethyl-di-n-propylthiocarbamate and S-propyl di-n-propylthiocarbamate.
Dipropylamine also is employed in the purification of perfluoro compounds to convert the incompletely fluorinated impurities to solids which are then removed by filtration.
In 1984, U.S. production of Dipropylamine was 41 million pounds.

Safety Profile:
Dipropylamine is moderately toxic by shin contact and inhalation.
Dipropylamine is a skin irritant.
Dipropylamine is a very dangerous fire hazard, when exposed to heat or flame.
Dipropylamine can react with oxidizers.
Dipropylamine explosion hazard is unknown.
Keep Dipropylamine away from heat and open flame.

Metabolism of Dipropylamine:
There is little information available on the metabolism and disposition of dipropylamine in biological systems.
The available evidence suggests that dipropylamine is not a substrate for monoamine oxidase, but rather is inhibitory.
Valiev administered dipropylamine intraperitoneally to rats and reported it to be moderately inhibitory to liver monoamine oxidase.

Previous work by this author demonstrated that lethal doses of dipropylamine and other secondary and tertiary amines significantly inhibited rat liver monoamine oxidase activity.
The carcinogenic N-nitrosodipropylamine has been detected in the stomach when dipropylamine (present in fish, vegetables and fruit juices) comes in contact with nitrite, which is often used as a food additive in meats and smoked fish.
Further metabolism of the carcinogen N-nitrosodipropylamine product formed upon nitrosation of dipropylamine is required to form a highly electrophilic carbonium ion capable of alkylating DNA, etc.

Di-n-propylamine is a member of the class of compounds known as dialkylamines.
Dialkylamines are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen.
Di-n-propylamine is soluble (in water) and a very strong basic compound (based on its pKa).
Di-n-propylamine can be found in a number of food items such as wild celery, orange bell pepper, yellow bell pepper, and pepper (c. annuum), which makes di-n-propylamine a potential biomarker for the consumption of these food products.

Dipropylamine hydrochloride is the hydrochloride salt of Dipropylamine (D492150).
Dipropylamine hydrochloride is also used as a reagent to prepare derivatives of 4-(2-N,N-di-n-propylaminoethyl)-5-hydroxyindole, some of which are potent, active dopaminergic agonists.

Air & Water Reactions of Dipropylamine:
Dipropylamine is highly flammable.
Dipropylamine is soluble in water.

Propylamine, dipropylamine and triplopylamine were adsorbed on sepiolite specimens under reflux, at their normal boiling points.
The infrared spectra of the original and the amine adsorbed specimens were recorded before and after heat treatments between 50-400"C.
The examination of the spectra revealed that the adsorption of amines took place by the replacement of the zeolitic water in the pores of the sepiolite by the amines.

Fire Hazard:
Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fires.

The relative density was 0.7401.
Boiling point 109~110 deg C.
Melting Point -63.6 °c.
Flash point 7 ℃.
Refractive index 4042.
The vapor pressure at 20 °c was 2.80 kPa.
Slightly soluble in water, soluble in ethanol and ether, etc.
Hydrate formation with water.

Dipropylamine - Preparation Method:
The N-propanol amination method is obtained by catalytic dehydrogenation, amination, dehydration and hydrogenation of propanol as a raw material (see tripropylamine).
Acrylonitrile hydrogenation method using acrylonitrile as a raw material and a copper-nickel compound as a catalyst, the catalytic hydrogenation is carried out at a temperature of 40-250 ° C.
And a pressure of 0-4.9 MPa to obtain dipropylamine.

Density: 0.7±0.1 g/cm3
Boiling Point: 108.8±0.0 °C at 760 mmHg
Melting Point: -63 °C
Molecular Formula: C6H15N
Molecular Weight: 101.190
Flash Point: 3.9±0.0 °C
Exact Mass: 101.120445
PSA: 12.03000
LogP: 1.70
Vapour Pressure: 25.5±0.2 mmHg at 25°C
Index of Refraction: 1.405
Stability: Stable. Highly flammable. Incompatible with strong oxidizing agents.
Water Solubility: soluble

Use and emission sources:
Manufacture of organic products, manufacture of pesticides

In this work, a comprehensive study of the hydrothermal synthesis and catalytic performance of SAPO-34 templated by the isomeric dipropylamine (DPA) and diisopropylamine (DIPA) was carried out.
SAPO-34 with a faster crystallization rate and lower Si content could be obtained with DIPA as the template, suggesting the better templating efficacy of DIPA than DPA.
Theoretical calculations reveal that DIPA possesses more favourable non-bonding interactions with the CHA framework and the electronic configuration is of vital importance in determining the template efficacy.
SAPO-34-DIPA with low silicon contents exhibits excellent performance, over which a maximum selectivity of ethylene plus propylene (87.2%) is observed.

This value should be among the top ever reported.
The surface Si enrichment on the crystals, which is both template- and condition-dependent, is revealed to be of significant influence in the catalytic performance.
The relatively homogenous Si distribution in the crystals, lower acid concentration and weaker acid strength corporately make SAPO-34-DIPA an excellent MTO catalyst.

Reactivity Profile of Dipropylamine:
DIPROPYLAMINE neutralizes acids in exothermic reactions to form salts plus water.
Dipropylamine may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Dipropylamine is flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Synonyms: N-propylpropan-1-amine, dipropylamine, N-dipropylamine, N-propyl-1-propanamine, N-propyl-propylamine

Molecular Weight: 101.19
XLogP3: 1.7
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 4
Exact Mass: 101.120449483
Monoisotopic Mass: 101.120449483
Topological Polar Surface Area: 12 Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 23.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

REASON FOR CITATION:
* Dipropylamine is on the Hazardous Substance List because it is cited by DOT, NFPA and EPA.
* Dipropylamine is on the Special Health Hazard Substance List because it is FLAMMABLE.

HAZARD SUMMARY:
-Dipropylamine can affect you when breathed in.
-Dipropylamine can severely irritate and burn the skin and eyes on contact.
-Breathing Dipropylamine can irritate the nose and throat causing coughing and wheezing.
-Breathing Dipropylamine can irritate the lungs causing coughing and/or shortness of breath. Higher exposures can cause a build-up of fluid in the lungs (pulmonary edema), a medical emergency, with severe shortness of breath.
-Exposure to Dipropylamine can cause headache, nausea, fainting, and anxiety.
-Dipropylamine is a FLAMMABLE LIQUID and a DANGEROUS FIRE HAZARD.

Density: 0.7400g/mL
Color: Undesignated
Melting Point: -63.0°C
Boiling Point: 105.0°C to 110.0°C
Flash Point: 7°C
Assay Percent Range: 98.5% min. (GC)
Infrared Spectrum: Authentic
Linear Formula: (CH3CH2CH2)2NH
Packaging: Glass bottle
Beilstein: 04, 138
Merck Index: 15, 3383
Refractive Index: 1.4030 to 1.4050
Quantity: 250mL
Solubility Information: Solubility in water: 46g/L (20°C). Other solubilities: freely soluble in alcohol
Specific Gravity: 0.74
Formula Weight: 101.19
Physical Form: Liquid
Percent Purity: 99%
Viscosity: 0.5 mPa.s (20°C)
Water : 0.2% max.
Chemical Name or Material: Dipropylamine, 99%

142-84-7 [RN]
1-Propanamine, N-propyl- [ACD/Index Name]
205-565-9 [EINECS]
DI-N-PROPYLAMINE
Dipropylamine [Wiki]
Dipropyl-amine
JL9200000
MFCD00009362 [MDL number]
n-Dipropylamine
n-propyl-1-propanamin [ACD/IUPAC Name]
N-Propyl-1-propanamin [German] [ACD/IUPAC Name]
N-Propyl-1-propanamine [ACD/IUPAC Name]
N-Propyl-1-propanamine [French] [ACD/IUPAC Name]
N-Propylpropan-1-amine
(n-C3H7)2NH [Formula]
3,3'-IMINODIPROPIONITRILE
345909-05-9 [RN]
63220-61-1 [RN]
92517-02-7 [RN]
DI(N-PROPYL)AMINE
DI(PROPYL-3,3,3-D3)AMINE
DI-N-PROPYL-1,1,2,2,3,3,3-D7-AMINE (MONO-PROPYL-D7)
Di-n-propylamin
Di-n-propyl-d14-amine
dipropilamina [Portuguese]
dipropyl amine
DiPropylamine Reagent Grade
dipropylammonium
EINECS 205-565-9
InChI=1/C6H15N/c1-3-5-7-6-4-2/h7H,3-6H2,1-2H
N,N-dipropylamine
N-Propyl-propylamine
STR03559
UN 2383
DIPROPYLAMINE
Di-n-propylamine
142-84-7
1-Propanamine, N-propyl-
N-propylpropan-1-amine
n-Dipropylamine
N-Propyl-1-propanamine
RCRA waste number U110
dipropyl amine
di(n-propyl)amine
UNII-60P318IIRY
DIPROPYL-AMINE
di-n-propylamin
60P318IIRY
RCRA waste no. U110
CCRIS 4805
HSDB 2644
EINECS 205-565-9
UN2383
BRN 0505974
di-propylamine
AI3-24037
di-n-propyl amine
N,N-Dipropylamine
N-propyl propylamine
N-propyl-propylamine
MFCD00009362
Dipropylamine, 99%
N,N-Dipropylamine #
N,N-di-n-propylamine
DSSTox_CID_5185
DiPropylamine Reagent Grade
EC 205-565-9
DSSTox_RID_77699
DSSTox_GSID_25185
SCHEMBL15445
(n-C3H7)2NH
CHEMBL3185961
DTXSID2025185
STR03559
ZINC1672989
Tox21_202085
BBL027756
STL194269
AKOS000118843
MCULE-6223802621
UN 2383
NCGC00249163-01
NCGC00259634-01
CAS-142-84-7
D0930
FT-0614098
FT-0625300
Dipropylamine [UN2383] [Flammable liquid]
104486-EP2292597A1
104486-EP2298761A1
104486-EP2301627A1
125304-EP2295424A1
Q410621
J-007705
J-520390
F2190-0303

Trade name
1-Propanamine, N-propyl- (9CI)
Di-n-propylamin
Di-n-propylamine
Di-n-propylamine (DnPA)
Dipropylamin
Dipropylamine
Dipropylamine (8CI)
N-Propyl-1-propanamine
n-Dipropylamine
sek. Alkylamin

Alternate Name(s)
N,N-Dipropylamine
(N-C3H7)2NH
Di-n-propyl amine
N-Dipropylamine
N-Propyl-1-propanamine
N-Propyl-propylamine
N-propylpropan-1-amine
AI3-24037
BRN 0505974
CCRIS 4805
EINECS 205-565-9
HSDB 2644
RCRA WASTE NO. U110
UN2383

Synonyms
N,N-Dipropylamine
N-Propyl-1-propanamine
Di-n-propylamine
2 propylamine
N-propylpropan-1-amine
N-propylpropan-1-aminium
DIPROPYLENE GLYCOL
DIPROPYLENE GLYCOL, N° CAS : 110-98-5 / 25265-71-8. Nom INCI : DIPROPYLENE GLYCOL. Nom chimique : 1,1'-Oxydipropan-2-ol; Oxydipropan-2-ol; Hydroxypropyloxypropanol, N° EINECS/ELINCS : 203-821-4 / 246-770-3, Classification : Glycol, Ses fonctions (INCI). Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Solvant : Dissout d'autres substances. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques. Noms français : 2,2'-Dihydroxydipropyl ether ANTROPYLENE GLYCOL DI-1,2-PROPYLENE GLYCOL Dipropylène glycol Ether di(hydroxy-2 prolylique) ETHER DIHYDROXY-2,2' ISOPROPYLIQUE Oxybis-1,1' propanol-2 OXYBISPROPANOL Noms anglais : 1,1'-Oxybis-2-propanol 1,1'-Oxydi-2-propanol Bis(2-hydroxypropyl) ether Ce produit peut aussi se trouver comme composant du dipropylène glycol (mélanges d'isomères) Utilisation et sources d'émission: Solvant de produits organiques, fabrication de polymères. 1,1'-Dimethyldiethylene glycol 1,1'-Oxybis(2-propanol) 1,1'-Oxydi(2-propanol) 1,1'-Oxydi(2-propanol) [German] 1,1'-Oxydi(2-propanol) [French] 1,1'-Oxydipropan-2-ol 1698372 [Beilstein] 203-821-4 [EINECS] 2-Propanol, 1,1'-oxybis- [ACD/Index Name] Di(propylene glycol) MFCD00004538 "1,1`-OXYDI-2-PROPANOL" [106-62-7] [110-98-5] 1-(2-hydroxypropoxy)propan-2-ol 1,1-oxybis(propan-2-ol) 1,1'-Oxybis(propan-2-ol) 1,1'-Oxybis-2-propanol 1,1'-Oxydi-2-propanol 1,1-Oxydi-2-Propanol 1,1prime-oxydipropan-2-ol 110-98-5 [RN] 2, 2'-Dihydroxyisopropyl ether 2,2'-Dihydroxydipropyl ether 25265-07-8 2-Propanol, 1,1'-oxydi- 4-Oxaheptane-2,6-diol Bis(2-hydroxypropyl) ether Bis(2-hydroxypropyl)ether Bis(hydroxypropyl) ether Di-(2-hydroxypropyl)-ether Di(propyleneglycol) Di-1,2-propylene glycol Dipropylene glycol Dipropylene glycol (mixture of isomers) Dipropylene Glycol Reagent Grade Dipropyleneglycol MFCD00051023 [MDL number] Oxybispropanol
DIPROPYLENE GLYCOL

Dipropylene glycol is a chemical compound with the molecular formula C6H14O3.
Dipropylene glycol is a clear, colorless liquid with a slight odor.
Dipropylene glycol belongs to the glycol ether family and is a member of the propylene glycol ethers group.

CAS Number: 25265-71-8
EC Number: 246-770-3



APPLICATIONS


Dipropylene glycol is widely used as a solvent and carrier in the formulation of personal care products such as lotions, creams, and shampoos.
In the pharmaceutical industry, Dipropylene glycol is used as a solvent in the formulation of oral, topical, and injectable medications.

Dipropylene glycol is utilized in the formulation of water-based paints and coatings as a coalescing agent, aiding in film formation.
Dipropylene glycol is used as a solvent and carrier for inks and dyes in the printing industry, ensuring even dispersion and flow properties.

In adhesives and sealants, Dipropylene glycol acts as a plasticizer, improving flexibility and adhesion.
Dipropylene glycol finds applications in the chemical industry as a solvent and reaction medium in various synthesis and purification processes.
Dipropylene glycol is used as a heat transfer fluid in HVAC systems, refrigeration units, and thermal storage systems.

Dipropylene glycol is employed as a solvent and carrier for fragrances in perfumes, colognes, and scented products.
In the agriculture industry, Dipropylene glycol is used as a solvent and stabilizer in pesticide and herbicide formulations.

Dipropylene glycol serves as a dye carrier in textile processing, aiding in the even and efficient dyeing of fabrics.
Dipropylene glycol finds applications in the production of fuel additives, lubricants, and hydraulic fluids, providing solvency and stability.

Dipropylene glycol is utilized as an ingredient in antifreeze and coolant formulations for automotive and industrial applications.
Dipropylene glycol is used in the formulation of photographic chemicals as a solvent and stabilizing agent.

Dipropylene glycol finds applications in the electronics industry as a cleaning agent for circuit boards and electronic components.
Dipropylene glycol is used as a lubricant, cooling agent, and rust inhibitor in metalworking fluids.
Dipropylene glycol finds applications in wood preservation formulations, protecting against fungal decay and wood-boring insects.

In the construction industry, Dipropylene glycol is used as a plasticizer in concrete admixtures, improving workability.
Dipropylene glycol is employed as a processing aid and softening agent in the rubber and polymer industry.
Dipropylene glycol is used as a stable and efficient heat transfer fluid in various industrial processes.

Dipropylene glycol finds applications in the formulation of firefighting foam, providing stability and heat resistance.
In the ceramic industry, Dipropylene glycol acts as a binder and plasticizer, improving the workability of clay.

Dipropylene glycol is used as an ingredient in automotive care products such as waxes, polishes, and interior cleaners.
Dipropylene glycol serves as a solvent for industrial metal cleaning and degreasing applications.

Dipropylene glycol is utilized in the production of foam products, such as mattresses, cushions, and insulation materials, as a blowing agent.
Dipropylene glycol finds applications in the formulation of automotive brake fluids, providing lubrication and heat resistance.

In the food and beverage industry, Dipropylene glycol can be used as a solvent for food colorants and flavorings, subject to specific regulations and limitations.
Dipropylene glycol serves as a viscosity regulator and solvent in the formulation of personal lubricants and intimate care products.
Dipropylene glycol finds applications in the manufacturing of metalworking fluids, improving cooling and lubrication properties during machining processes.

Dipropylene glycol is utilized in the formulation of leather dyes and finishes, enhancing color penetration and surface appearance.
In the textile industry, Dipropylene glycol can be used as a solvent for textile dyeing and printing processes.

Dipropylene glycol is employed as a component in drilling fluids used in the oil and gas industry, providing lubrication and temperature stability.
Dipropylene glycol is used as a moisture regulator and softening agent in tobacco products.

Dipropylene glycol finds applications in the formulation of household and industrial cleaners, providing solvency and degreasing properties.
In the cosmetic industry, Dipropylene glycol is used as a solubilizer and stabilizer for active ingredients in skincare and hair care products.
Dipropylene glycol serves as a diluent and carrier for fragrance oils in perfumes, body sprays, and scented candles.

Dipropylene glycol finds applications in the production of emulsions and suspensions in the pharmaceutical and cosmetic industries.
Dipropylene glycol is used as a solvent and carrier for vitamins, minerals, and nutritional supplements in dietary and nutritional products.

In the paint and coatings industry, Dipropylene glycol can be used as a co-solvent and viscosity modifier, enhancing flow and leveling properties.
Dipropylene glycol is employed as a solvent and extraction agent in botanical and herbal extracts for medicinal and cosmetic applications.

Dipropylene glycol finds applications in the formulation of air fresheners and deodorizers, providing a long-lasting fragrance.
Dipropylene glycol is used as a carrier and diluent for flavors and food additives in the food and beverage industry.
In the construction industry, Dipropylene glycol is used as an additive in cementitious materials to improve workability and reduce shrinkage.

Dipropylene glycol serves as a solvent for oil-based inks in the printing industry, providing good wetting and spreading properties.
Dipropylene glycol is utilized as a solvent and carrier for active ingredients in pest control formulations, such as insecticides and rodenticides.

Dipropylene glycol is used in the production of inkjet printing inks, providing stability and viscosity control.
In the petrochemical industry, Dipropylene glycol can be used as a component in fuel additives and refinery processes.

Dipropylene glycol finds applications in the formulation of household and industrial air fresheners, providing a pleasant aroma and long-lasting effect.
Dipropylene glycol is utilized in the production of ceramic glazes and enamels, enhancing adhesion and color development.


Dipropylene glycol has a wide range of applications across different industries.
Some of its key applications include:

Personal care products:
Dipropylene glycol is used in the formulation of cosmetics, skincare products, and hair care products as a solvent, humectant, and viscosity modifier.

Pharmaceuticals:
Dipropylene glycol finds applications in the pharmaceutical industry as a solvent and a component in oral, topical, and injectable medications.

Cleaning products:
Dipropylene glycol is utilized in household and industrial cleaners as a solvent, viscosity regulator, and ingredient for degreasers and stain removers.

Paints and coatings:
Dipropylene glycol serves as a coalescing agent in water-based paints and coatings, helping the film-forming components merge and form a uniform film upon drying.

Inks and dyes:
Dipropylene glycol is used as a solvent and viscosity modifier in the formulation of inks and dyes, aiding in the dispersion of colorants and enhancing flow properties.

Adhesives:
Dipropylene glycol is employed as a solvent and plasticizer in adhesive formulations, contributing to the adhesion and flexibility of the adhesive.

Chemical processing:
Dipropylene glycol finds applications as a solvent, reaction medium, and extraction agent in various chemical processes, such as synthesis, purification, and separation.

Industrial applications:
Dipropylene glycol is used as a heat transfer fluid, providing efficient and stable heat exchange in systems like refrigeration, HVAC, and thermal storage.

Fragrances:
Dipropylene glycol is utilized as a solvent and carrier for fragrances in perfumes, colognes, air fresheners, and scented products.

Agriculture:
Dipropylene glycol is used in the formulation of pesticides and herbicides as a solvent and a stabilizer for active ingredients.

Textiles:
Dipropylene glycol finds applications in textile processing as a dye carrier, aiding in the even and efficient dyeing of fabrics.

Fuel and oil industry:
Dipropylene glycol is employed as a solvent, viscosity modifier, and anti-icing additive in fuel additives, lubricants, and hydraulic fluids.

Antifreeze and coolant:
Dipropylene glycol is used as an ingredient in antifreeze and coolant formulations for automotive and industrial applications, providing freeze protection and heat transfer capabilities.

Photographic chemicals:
Dipropylene glycol finds use in photographic developers and fixers as a solvent and a stabilizing agent.

Electronic devices:
Dipropylene glycol is utilized in the manufacturing of electronic devices as a cleaning agent for circuit boards and components.

Metalworking fluids:
Dipropylene glycol is used in metalworking fluids as a lubricant, cooling agent, and rust inhibitor.

Wood preservatives:
Dipropylene glycol finds applications in wood preservation formulations, helping to protect against fungal decay and wood-boring insects.

Concrete additives:
Dipropylene glycol can be used as a plasticizer in concrete admixtures, improving workability and reducing water content.

Rubber and polymer industry:
Dipropylene glycol is employed as a processing aid and softening agent in the production of rubber and polymer materials.

Heat transfer fluids:
Dipropylene glycol is used in heat transfer systems and equipment as a stable and efficient medium for transferring thermal energy.

Air fresheners:
Dipropylene glycol is used as a solvent and carrier for fragrances in air fresheners, providing a long-lasting scent.

Printing industry:
Dipropylene glycol finds applications in the printing industry as a solvent for ink formulations, aiding in the dispersion of pigments and enhancing print quality.

Ceramic industry:
Dipropylene glycol is utilized as a binder and plasticizer in ceramic and pottery production, improving the workability and flexibility of clay.

Automotive products:
Dipropylene glycol is used in the formulation of automotive care products such as car waxes, polishes, and interior cleaners, providing solvency and shine.

Mold release agent:
Dipropylene glycol can be used as a mold release agent in various molding processes, preventing sticking and facilitating the release of molded objects.

Airplane de-icing fluid:
Dipropylene glycol is employed as an ingredient in de-icing fluids for airplanes, helping to remove ice and snow from aircraft surfaces.

Firefighting foam:
Dipropylene glycol can be used as a component in fire-extinguishing foam formulations, providing foam stability and heat resistance.

Leather processing:
Dipropylene glycol finds applications in the leather industry as a softening agent, aiding in the conditioning and finishing of leather products.

Food and beverage industry:
In the food industry, Dipropylene glycol can be used as a solvent for food colorants, flavors, and preservatives, subject to specific regulations and limitations.

Metal cleaning and degreasing:
Dipropylene glycol is utilized in metal cleaning formulations as a solvent for removing grease, oils, and contaminants from metal surfaces.



DESCRIPTION


Dipropylene glycol is a chemical compound with the molecular formula C6H14O3.
Dipropylene glycol is a clear, colorless liquid with a slight odor.
Dipropylene glycol belongs to the glycol ether family and is a member of the propylene glycol ethers group.

Dipropylene glycol is produced by the reaction of propylene oxide with water.
Dipropylene glycol consists of two propylene glycol units connected by an ether linkage, hence the name "dipropylene."
Dipropylene glycol has a higher molecular weight and viscosity compared to its counterpart, propylene glycol.

Dipropylene glycol is hygroscopic, meaning it can absorb moisture from the air.
Dipropylene glycol has good solvency properties, making it miscible with a wide range of solvents, including water, alcohols, and many organic compounds.

Dipropylene glycol has a relatively low volatility and a high boiling point, making it useful in various applications.
Dipropylene glycol is a clear, colorless liquid with a slight, sweet odor.

Dipropylene glycol has a molecular formula of C6H14O3.
Dipropylene glycol is composed of two propylene glycol units linked by an ether bond.
Dipropylene glycol has a relatively high boiling point of around 232°C (450°F).

Dipropylene glycol is soluble in water and many organic solvents.
The viscosity of Dipropylene glycol is higher than that of propylene glycol.

Dipropylene glycol is stable under normal conditions and is not known to undergo spontaneous decomposition.
Dipropylene glycol has good solvent properties and is miscible with many organic compounds.

Dipropylene glycol is used as a solvent in the formulation of medications, both oral and topical.
Dipropylene glycol is employed as a coalescing agent in paints and coatings to promote film formation and improve performance.

Dipropylene glycol finds use in cleaning products as a solvent and viscosity modifier.
Dipropylene glycol is utilized in the fragrance industry as a carrier and solvent for fragrances.

Dipropylene glycol is an ingredient in some fuel additives and lubricants.
Dipropylene glycol is used as a heat transfer fluid in industrial applications.
Dipropylene glycol serves as a reaction medium and solvent in various chemical processes.

Dipropylene glycol is employed as a dye carrier and solvent in textile processing.
Dipropylene glycol is considered a versatile compound with excellent solvency properties and is valued for its stability and compatibility with a wide range of materials.



PROPERTIES


Chemical formula: C6H14O3
Molecular weight: 134.17 g/mol
Appearance: Colorless, clear liquid
Odor: Slight, characteristic odor
Density: 1.01 g/cm³
Melting point: -48 °C (-54 °F)
Boiling point: 230-233 °C (446-451 °F)
Flash point: 126 °C (259 °F)
Solubility: Miscible in water and many organic solvents
Vapor pressure: 0.002 mmHg at 20 °C
Viscosity: 8.3 cP at 20 °C
pH: Neutral (approximately 7)
Refractive index: 1.441 at 20 °C
Heat of vaporization: 56.6 kJ/mol
Heat capacity: 2.57 J/g·K
Evaporation rate: Moderate
Flammability: Non-flammable
Oxidizing properties: Non-oxidizing
Vapor density: 4.6 (air = 1)



FIRST AID


Inhalation:

If inhaled, remove the person to fresh air and ensure they are in a well-ventilated area.
If breathing is difficult, seek medical attention immediately.
If the person is not breathing, perform artificial respiration, preferably using a pocket mask equipped with a one-way valve or a bag-valve mask.
Keep the person calm and at rest.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected skin thoroughly with soap and water for at least 15 minutes.
If irritation or redness persists, seek medical attention.
Wash contaminated clothing before reusing.


Eye Contact:

Rinse the eyes gently with water for at least 15 minutes, holding the eyelids open to ensure thorough flushing.
Remove contact lenses, if present and easy to do so, after rinsing for the first few minutes.
Seek immediate medical attention if irritation or pain persists.


Ingestion:

Rinse the mouth with water and drink plenty of water to dilute the chemical.
Do NOT induce vomiting unless instructed to do so by medical personnel.
Seek medical attention immediately.
Do not give anything by mouth to an unconscious person.



HANDLING AND STORAGE


Handling:

Wear appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing when handling Dipropylene glycol.
Ensure good ventilation in the working area to minimize inhalation of vapors.
Avoid contact with eyes, skin, and clothing.

In case of contact, follow the first aid measures mentioned earlier.
Avoid ingestion and smoking in areas where Dipropylene glycol is handled.
Use proper handling and transfer equipment such as closed systems, pumps, or pipettes to minimize the release of the chemical.

Do not eat, drink, or store food in areas where Dipropylene glycol is handled.
Wash hands thoroughly with soap and water after handling the chemical.


Storage:

Store Dipropylene glycol in a cool, dry, well-ventilated area away from direct sunlight and incompatible materials.
Keep containers tightly closed when not in use to prevent evaporation and contamination.
Store in approved containers made of compatible materials, such as stainless steel, polyethylene, or glass.

Ensure proper labeling of containers with the name of the chemical, hazards, and appropriate warning symbols.
Separate Dipropylene glycol from strong oxidizing agents and sources of ignition to prevent the risk of fire or chemical reactions.

Follow local regulations and guidelines for storage quantities and requirements.
Keep storage areas secure and restricted to authorized personnel only.

Store Dipropylene glycol away from heat sources and open flames to prevent ignition and fire hazards.
Avoid storing near strong acids, bases, or reactive chemicals that may react with Dipropylene glycol.
Ensure proper segregation from food, beverages, and feedstuffs to avoid contamination.



SYNONYMS


DPG
2,2'-Oxybispropanol
Bis(2-hydroxypropyl) ether
Dipropylene ether
1,1'-Oxybis-2-propanol
2-Hydroxyisopropyl ether
Propane-1,1-diyl bis(2-hydroxypropane-2-carboxylate)
1,1'-Bis(2-hydroxypropyl) ether
2,2'-Dihydroxydipropanol
2-Hydroxypropyl ether
2-(2-Hydroxypropoxy)propan-1-ol
Oxybispropanol
1,1'-Bis(hydroxymethyl)ether
2-(2-Hydroxypropoxy)-1-propanol
1,1'-Bis(2-hydroxypropan-2-yl) ether
Hydroxypropyl ether
Bis(propylene glycol) ether
2,2'-Bis(2-hydroxypropoxy)propane
Bis(1-methylethyl) glycol ether
Propylene glycol, dipropyl ether
2-Hydroxypropyl 1,1'-oxybis(propane-2,1-diyl) ether
2,2'-Dihydroxydipropyl ether
Dipropylene glycol monopropyl ether
Propane-1,1-diylbis(propane-2,1-diyl) bis(hydrogen sulfate)
Propylene glycol dipropionate
2,2'-Dihydroxydipropanol
Propanediol, bis(2-hydroxypropyl) ether
1,1'-Bis(2-hydroxypropyl) propanediol
1,1'-Bis(propan-2-yl) ether of propanediol
Dipropylene glycol monoethyl ether
2,2'-Dihydroxy-3,3'-dipropoxy-5,5'-dipropanol
Propylene glycol dibutyl ether
Bis(2-hydroxypropyl) propane-1,2-diol
2-Hydroxypropyl dipropylene glycol ether
1,1'-Bis(hydroxypropyl) dipropyl ether
Dipropylene glycol dibutyl ether
2-(2-Hydroxypropoxy)propane-1,3-diol
Dipropylene glycol dimethyl ether
2,2'-Dihydroxydipropyl ether of diethylene glycol
Propanediol, dipropyl ether
1,1'-Bis(hydroxypropyl) dipropylene glycol ether
1,1'-Bis(propan-2-yl) ether of propane-1,2-diol
Dipropylene glycol butyl ether
1,1'-Bis(propan-2-yl) ether of 1,2-propanediol
2,2'-Dihydroxydipropyl ether of propylene glycol
Propane-1,1-diyl bis(2-hydroxypropane-1,2-diyl) ether
1,1'-Bis(propan-2-yl) ether of 1,3-propanediol
Dipropylene glycol dihexyl ether
1,1'-Bis(2-hydroxypropyl) ether of propane-1,2-diol
1,1'-Bis(propan-2-yl) ether of propylene glycol
Dipropylene glycol dibenzoate
1,1'-Bis(propan-2-yl) ether of 1,4-butanediol
1,1'-Bis(hydroxypropyl) ether of propane-1,3-diol
Dipropylene glycol diacetate
2,2'-Dihydroxydipropyl ether of diethylene glycol
Dipropylene glycol diethyl ether
1,1'-Bis(propan-2-yl) ether of propane-1,4-diol
Dipropylene glycol diisobutyl ether
2,2'-Dihydroxydipropyl ether of 1,4-butanediol
Dipropylene glycol dimethacrylate
1,1'-Bis(hydroxypropyl) ether of propane-1,4-diol
Dipropylene glycol diisopropyl ether
2,2'-Dihydroxydipropyl ether of triethylene glycol
Dipropylene glycol dimethylacrylate
1,1'-Bis(hydroxypropyl) ether of propylene glycol
Dipropylene glycol methyl ether
2,2'-Dihydroxydipropyl ether of 1,6-hexanediol
Dipropylene glycol dimethyl ether sulfate
1,1'-Bis(hydroxypropyl) ether of 1,3-propanediol
Dipropylene glycol monomethyl ether
2,2'-Dihydroxydipropyl ether of 1,5-pentanediol
Dipropylene glycol diethyl carbonate
1,1'-Bis(propan-2-yl) ether of ethylene glycol
Dipropylene glycol butyl ether acetate
2,2'-Dihydroxydipropyl ether of 1,3-butanediol
DIPROPYLENE GLYCOL BUTYL ETHER

Dipropylene glycol butyl ether, also known as Dipropylene glycol monobutyl ether or Dipropylene glycol butyl ether, is a chemical compound with the molecular formula C10H22O4.
Dipropylene glycol butyl ether is classified as a glycol ether, which is a type of organic compound commonly used as a solvent in various industrial and consumer applications.
Dipropylene glycol butyl ether is a clear, colorless liquid with low volatility, and it is known for its ability to dissolve a wide range of substances, making it valuable in formulations for products such as paints, coatings, cleaners, and adhesives.
Dipropylene glycol butyl ether is often chosen for its balance of solvency, low odor, and low volatility, making it suitable for applications where controlled evaporation and good solvency are essential.

CAS Number: 29911-28-2
EC Number: 249-841-0



APPLICATIONS


Dipropylene glycol butyl ether is commonly used as a solvent in the formulation of water-based coatings and paints, including those for walls, furniture, and automotive applications.
Dipropylene glycol butyl ether is employed as a coalescent in latex paint formulations, aiding in the formation of a continuous and durable paint film.
In the automotive industry, Dipropylene glycol butyl ether is used in the production of automotive coatings, including basecoats and clearcoats, for vehicles.
Dipropylene glycol butyl ether is a key ingredient in the manufacturing of wood finishes and stains, providing protection and enhancing the appearance of wooden surfaces.

Dipropylene glycol butyl ether is used in printing ink formulations, where it improves ink quality, adhesion, and printability on various substrates.
Dipropylene glycol butyl ether serves as a solvent and diluent in the production of adhesives and sealants, aiding in their application and bonding strength.
Dipropylene glycol butyl ether is utilized in the formulation of industrial coatings for metal surfaces, offering corrosion resistance and aesthetic appeal.

In the cleaning and maintenance industry, it is found in the production of cleaning agents and degreasers for removing dirt, grease, and oils.
Dipropylene glycol butyl ether is used in the creation of industrial and household cleaning products, where it enhances the cleaning performance.

Dipropylene glycol butyl ether is employed in the production of specialty lubricants used in various machinery maintenance and lubrication applications.
The agricultural sector utilizes Dipropylene glycol butyl ether in the formulation of herbicides and crop protection products to improve their effectiveness.

In the cosmetics and personal care industry, it can be found in perfumes and lotions for its ability to disperse and solubilize fragrances and other ingredients.
Dipropylene glycol butyl ether is a component in anti-icing and de-icing agents for aircraft and runways to prevent ice buildup.
Dipropylene glycol butyl ether is used in the production of degreasing agents for industrial and automotive applications to remove oils and greases.

Dipropylene glycol butyl ether is found in the formulation of metalworking fluids, such as cutting oils and coolants, to improve machining and grinding operations.
In the printing industry, it is employed in the production of flexographic and gravure inks for high-quality printing on various substrates.

Dipropylene glycol butyl ether is used in the formulation of personal care products, including skincare and hair care items, to enhance their texture and spreadability.
Dipropylene glycol butyl ether can be found in the production of household and institutional cleaners, including glass and surface cleaners.
Dipropylene glycol butyl ether is used as a coupling agent in pesticide formulations, helping distribute active ingredients evenly on plants.
Dipropylene glycol butyl ether serves as a carrier solvent in the formulation of insect repellents and personal insect protection products.

Dipropylene glycol butyl ether is used in the creation of rust inhibitors and rust preventatives to protect metal surfaces from corrosion.
In the plastics industry, Dipropylene glycol butyl ether is employed as a plasticizer and processing aid to improve extrusion and molding processes.

Dipropylene glycol butyl ether is utilized in the formulation of heat transfer fluids for various industrial applications, including data centers and manufacturing facilities.
In the leather and textile industries, it aids in dyeing processes, ensuring uniform coloration of fabrics and leather goods.

Dipropylene glycol butyl ether can be found in the production of heat-sealing adhesives for packaging and sealing applications, such as food packaging and labeling.
Dipropylene glycol butyl ether is used in the formulation of architectural and decorative paints, including interior and exterior paints and coatings.

In the construction industry, it is added to concrete admixtures to improve workability and reduce water content while maintaining strength.
Dipropylene glycol butyl ether is employed in the production of varnishes for wood and metal, enhancing their protective and aesthetic qualities.
Dipropylene glycol butyl ether is used in the creation of inkjet printer inks for high-resolution and fast-drying printing on a variety of substrates.

Dipropylene glycol butyl ether can be found in the formulation of screen printing inks for textiles, ceramics, and graphic arts applications.
Dipropylene glycol butyl ether serves as a component in stain removers and spot cleaners for fabrics, upholstery, and carpets.

Dipropylene glycol butyl ether is utilized in the production of degreasing agents for industrial equipment, machinery, and automotive parts.
Dipropylene glycol butyl ether is added to disinfectants and sanitizers for improved germ-killing and cleaning performance.

In the oil and gas industry, Dipropylene glycol butyl ether is used as a drilling mud additive to improve drilling efficiency and hole cleaning.
Dipropylene glycol butyl ether is employed as a solvent in the formulation of adhesives for woodworking, construction, and industrial bonding applications.
Dipropylene glycol butyl ether is used in the creation of rust and corrosion inhibitors for the protection of metal structures and equipment.

In the production of household and personal care products, it aids in the formulation of perfumes, shampoos, and lotions.
Dipropylene glycol butyl ether can be found in the manufacturing of specialty inks, including conductive inks for electronics and circuitry.
Dipropylene glycol butyl ether is used in the production of stamp pad inks, ensuring even ink distribution and clarity in stamp impressions.

Dipropylene glycol butyl ether serves as a component in solvent-based wood preservatives and wood treatments.
Dipropylene glycol butyl ether is employed in the formulation of lubricating oils and greases for industrial machinery and automotive applications.

Dipropylene glycol butyl ether can be used as a wetting agent in the textile industry to improve dye penetration and color fastness.
In the agricultural sector, it is employed in pesticide formulations to enhance the spreading and adherence of active ingredients.

Dipropylene glycol butyl ether is added to hydraulic fluids to improve lubrication and protect hydraulic systems.
Dipropylene glycol butyl ether is used in the creation of heat-resistant coatings for industrial equipment, including ovens and stoves.

Dipropylene glycol butyl ether is found in the formulation of cooling water treatment chemicals to prevent scale buildup and corrosion in industrial cooling systems.
Dipropylene glycol butyl ether is utilized as a solvent in the production of leather dyes, ensuring even and vibrant coloration.
Dipropylene glycol butyl ether can be used as a humectant in the formulation of air fresheners and room sprays.

In the manufacture of detergents, it aids in the solubilization of active cleaning agents and enhances stain removal.
Dipropylene glycol butyl ether can be added to floor and tile cleaning solutions to improve cleaning efficiency and remove tough stains and dirt.
In the textile industry, Dipropylene glycol butyl ether is used as a dye dispersant to ensure even and consistent coloration of textiles and fabrics.

Dipropylene glycol butyl ether is employed in the formulation of water-based inkjet inks for office and home printers, offering fast-drying and high-quality printing results.
Dipropylene glycol butyl ether can be found in the production of wood adhesives, enhancing bonding strength and durability in woodworking applications.
Dipropylene glycol butyl ether is utilized in the manufacturing of graffiti removers and paint strippers for the removal of paint and graffiti from various surfaces.
In the electronics industry, it is used as a solvent in the production of electronic cleaning agents and flux removers.

Dipropylene glycol butyl ether serves as a key component in ink formulations for flexographic printing, which is commonly used for packaging materials.
Dipropylene glycol butyl ether is employed in the creation of contact lens solutions, where it helps to solubilize and clean contact lenses effectively.
Dipropylene glycol butyl ether can be found in the formulation of brake fluids for automotive and industrial applications, ensuring reliable braking performance.

Dipropylene glycol butyl ether is used in the production of drilling muds for oil and gas drilling operations to improve drilling efficiency and reduce friction.
Dipropylene glycol butyl ether is employed in the formulation of heat transfer fluids for cooling and heating systems, including solar thermal systems.

Dipropylene glycol butyl ether is used in the manufacturing of heat-sealing adhesives for sealing and packaging applications in the food and pharmaceutical industries.
In the production of automotive antifreeze and coolant solutions, it serves as a component to lower the freezing point and prevent overheating.

Dipropylene glycol butyl ether can be found in the formulation of air fresheners and deodorizers for homes, offices, and vehicles.
Dipropylene glycol butyl ether is used in the creation of windshield washer fluids, improving cleaning performance and de-icing capabilities for vehicles.
Dipropylene glycol butyl ether is employed in the manufacturing of heat-resistant coatings for kitchen appliances, stovetops, and ovens.

In the petrochemical industry, it is used as a diluent and solvent for catalysts and process chemicals.
Dipropylene glycol butyl ether is utilized in the formulation of cutting and grinding fluids for metalworking, improving tool life and workpiece quality.

Dipropylene glycol butyl ether is added to hydraulic brake fluids, ensuring proper lubrication and corrosion protection in automotive braking systems.
Dipropylene glycol butyl ether is found in the production of disinfectants for hospitals and healthcare facilities, aiding in infection control and cleanliness.

Dipropylene glycol butyl ether serves as a component in odor control products, such as pet odor eliminators and air purifiers.
Dipropylene glycol butyl ether is employed in the creation of flux removers for electronics assembly, effectively removing soldering flux residues.
Dipropylene glycol butyl ether can be found in the formulation of cleaning products for industrial and commercial kitchens, breaking down grease and food residues.

Dipropylene glycol butyl ether is used in the production of heat transfer fluids for geothermal heating and cooling systems.
In the ceramics industry, it aids in the formulation of ceramic glazes for pottery and tile applications.
Dipropylene glycol butyl ether is utilized in the creation of specialty coatings for solar panels and photovoltaic cells to improve efficiency and longevity.



DESCRIPTION


Dipropylene glycol butyl ether, also known as Dipropylene glycol monobutyl ether or Dipropylene glycol butyl ether, is a chemical compound with the molecular formula C10H22O4.
Dipropylene glycol butyl ether is classified as a glycol ether, which is a type of organic compound commonly used as a solvent in various industrial and consumer applications.

Dipropylene glycol butyl ether is a clear, colorless liquid with low volatility, and it is known for its ability to dissolve a wide range of substances, making it valuable in formulations for products such as paints, coatings, cleaners, and adhesives.
Dipropylene glycol butyl ether is often chosen for its balance of solvency, low odor, and low volatility, making it suitable for applications where controlled evaporation and good solvency are essential.

Dipropylene glycol butyl ether is a clear, colorless liquid with a mild, almost odorless scent.
Dipropylene glycol butyl ether is a glycol ether known for its versatile solvency and low volatility.

Dipropylene glycol butyl ether is derived from the reaction of dipropylene glycol with n-butanol.
Dipropylene glycol butyl ether is often chosen for its ability to dissolve a wide range of substances, making it a valuable solvent in various applications.
Dipropylene glycol butyl ether is commonly used in the formulation of water-based coatings and paints.

Dipropylene glycol butyl ether is prized for its balanced properties, providing good solvency without excessive odor or rapid evaporation.
Dipropylene glycol butyl ether is hygroscopic, meaning it can absorb moisture from the air, making it useful in humidity control applications.

Dipropylene glycol butyl ether is considered relatively safe for handling when appropriate precautions are taken.
Dipropylene glycol butyl ether is compatible with a variety of resin systems used in the paint and coating industry.

In the automotive industry, it is used in the production of automotive coatings, including basecoats and clearcoats.
Dipropylene glycol butyl ether is utilized in the formulation of industrial coatings for various substrates, including metals, plastics, and concrete.
Dipropylene glycol butyl ether is used in the manufacturing of wood finishes and stains for furniture and flooring.

Dipropylene glycol butyl ether can be found in printing ink formulations, improving ink quality and adhesion to printing substrates.
In the cleaning and maintenance industry, it is used in the production of cleaning agents and degreasers.
Dipropylene glycol butyl ether is employed in the formulation of adhesives and sealants for improved workability and bonding strength.



PROPERTIES


Chemical Formula: C10H22O4
Molecular Weight: Approximately 206.29 g/mol
Physical State: Clear, colorless liquid
Odor: Mild, characteristic odor
Melting Point: Approximately -73.5°C (-100.3°F)
Boiling Point: Approximately 202-210°C (395.6-410°F)
Density: Approximately 0.94 g/cm³ at 20°C (68°F)
Solubility:
Highly soluble in water.
Miscible with a wide range of organic solvents, including alcohols, ketones, and ethers.
Vapor Pressure: Low to moderate at room temperature.
Viscosity: Moderate to high viscosity.
Flash Point: Approximately 94°C (201.2°F) closed cup
Autoignition Temperature: Approximately 228°C (442.4°F)
Refractive Index: Approximately 1.431 at 20°C (68°F)
Surface Tension: Approximately 32.5 dyn/cm at 20°C (68°F)
pH: Approximately neutral (pH 7)
Heat of Combustion: Approximately 3,415 kJ/kg
Heat of Vaporization: Approximately 214 J/g
Dielectric Constant: Approximately 7.3 at 20°C (68°F)



FIRST AID


Inhalation:

If Dipropylene glycol butyl ether vapors are inhaled, move the affected person to an area with fresh air immediately.
If the person is not breathing and qualified to do so, administer artificial respiration.
Seek immediate medical attention, even if symptoms appear mild.


Skin Contact:

In case of skin contact with Dipropylene glycol butyl ether, remove contaminated clothing and shoes.
Wash the affected skin thoroughly with soap and water for at least 15 minutes.
Seek medical attention if skin irritation, redness, or other symptoms develop.


Eye Contact:

If Dipropylene glycol butyl ether comes into contact with the eyes, immediately rinse the affected eye(s) with gently flowing water for at least 15 minutes, keeping the eyelids open to ensure thorough rinsing.
Seek immediate medical attention.
Do not use eye drops or other eye medications without medical advice.


Ingestion:

If Dipropylene glycol butyl ether is ingested, do not induce vomiting.
Rinse the mouth thoroughly with water if the person is conscious.
Seek immediate medical attention.
Do not give anything by mouth to an unconscious person.


General First Aid:

If any symptoms of exposure, such as dizziness, headache, or nausea, occur, seek medical attention.
Provide the medical personnel with information about the chemical and its properties.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling Dipropylene glycol butyl ether, wear appropriate PPE, including chemical-resistant gloves, safety goggles or face shield, lab coat or protective clothing, and respiratory protection if necessary.

Ventilation:
Work with Dipropylene glycol butyl ether in well-ventilated areas or use local exhaust ventilation to prevent the buildup of vapor concentrations.
Ensure that the ventilation system effectively removes airborne contaminants.

Avoidance of Contact:
Avoid skin and eye contact. In case of contact, follow first aid measures promptly.

No Eating or Drinking:
Do not eat, drink, or smoke while handling the chemical.
Wash hands thoroughly before eating, drinking, or using the restroom.

Prevent Inhalation:
Avoid breathing vapors or mist. Use respiratory protection as required based on exposure levels.

Prevent Spills:
Take precautions to prevent spills. Use appropriate spill control measures, including absorbent materials, to clean up and contain spills promptly.

Storage:
Store Dipropylene glycol butyl ether in a cool, dry, and well-ventilated area away from incompatible materials.
Keep containers tightly closed when not in use.

Labeling:
Ensure containers are clearly labeled with the name of the chemical, hazard warnings, and appropriate safety information.

Separation:
Store away from strong oxidizing agents, acids, and bases to avoid potential chemical reactions.

Electrical Equipment:
Use explosion-proof electrical equipment in areas where Dipropylene glycol butyl ether is handled.

Handling Containers:
When transferring the chemical from one container to another, use approved containers and equipment to prevent leaks or spills.


Storage:

Temperature:
Store Dipropylene glycol butyl ether at temperatures between 0°C (32°F) and 30°C (86°F) to maintain stability and prolong shelf life.

Ventilation:
Ensure storage areas are well-ventilated to disperse any potential vapors.

Container Material:
Use containers made of compatible materials such as stainless steel, carbon steel, or polyethylene.

Avoid Sunlight:
Store containers away from direct sunlight and other heat sources to prevent temperature fluctuations.

Separation:
Keep Dipropylene glycol butyl ether containers separated from food and beverage storage areas and away from children and unauthorized personnel.

Security:
Store in a secure location to prevent unauthorized access or tampering.

Fire Prevention:
Keep containers away from potential ignition sources or open flames.

Leak Control:
Maintain spill control and containment measures to prevent leakage and environmental contamination.

Emergency Equipment:
Ensure that safety showers and eye wash stations are readily available in the storage area.

Compatibility:
Store away from incompatible materials and hazardous chemicals. Refer to the manufacturer's guidelines and safety data sheet (SDS) for specific storage instructions.



SYNONYMS


Dipropylene glycol monobutyl ether
Butyl Carbitol
Butyl Di-propasol
DPGMEB
Dipropylene glycol n-butyl ether
DOWANOL™ DPnB
O-Dowanol™ 25B
Butyl dipropylene glycol
O-Butyl Oxitol
2-(2-Butoxyethoxy)propan-1-ol
2-(2-Butoxyethoxy)-1-propanol
2-(2-N-Butoxyethoxy)-1-propanol
Butoxyethoxypropanol
BDGME
Butyl Diglyme
1-Butoxy-2-(2-butoxyethoxy)propan-2-ol
2,2'-Oxybis(1-butanol)
Butyl Carbitol Acetate
Butyl Carbitol, 2-[(2-butoxyethoxy)methyl]oxirane
Butyl Di-Glyme
Dowanol DB
DIPROPYLENE GLYCOL DIBENZOATE
Dipropylene Glycol Dibenzoate is a diester of polypropylene glycol and benzoic acid.
Dipropylene glycol dibenzoate is an odorless, colorless, water-soluble and hygroscopic liquid.


CAS Number: 27138-31-4 / 94-51-9
EC Number: 248-258-5
Chem/IUPAC Name: Oxydipropyl dibenzoate
Linear Formula: (C6H5CO2C3H6)2O


Dipropylene glycol dibenzoate is a Polyoxypropylene glycol diester of benzoic acid.
Dipropylene glycol dibenzoate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Dipropylene glycol dibenzoate is also claimed to have some humectant and moisturizing properties without a greasy after-feel.
But Dipropylene glycol dibenzoate's real superpower is being an outstanding solvent for hard to solubilize sunscreen agents (that is most of the chemical sunscreen filters) making it an excellent emollient choice in high SPF products.


Dipropylene glycol dibenzoate is a polar, high-solvating plasticizer.
Dipropylene glycol dibenzoate is compatible with a wide range of polar polymers and rubbers.
Dipropylene glycol dibenzoate is useful in applications such as latex caulks, adhesive, and sealants, coatings and vinyl plastisols.


Dipropylene glycol dibenzoate is a polar, high-solvating plasticizer.
Dipropylene glycol dibenzoate is compatible with a wide range of polar polymers and rubbers.
Dipropylene glycol dibenzoate is useful in applications such as latex caulks, adhesive, and sealants, coatings and vinyl plastisols.


Dipropylene glycol dibenzoate is a kind of high purity product, suitable for flavor, cosmetics and other applications sensitive to odor.
Dipropylene glycol dibenzoate is an odorless, colorless, water-soluble and hygroscopic liquid.
Dipropylene glycol dibenzoate has a low vapor pressure and a moderate viscosity.


Dipropylene glycol dibenzoate can also play a role in unsaturated resins and saturated resins.
Dipropylene glycol dibenzoate produces resins with superior softness.


Dipropylene glycol dibenzoate has crack resistance and weather resistance.
Dipropylene glycol dibenzoate is the long-term yellowing resistance of the product is the value
Dipropylene glycol dibenzoate is an oily liquid that makes your skin nice and smooth (aka emollient).



USES and APPLICATIONS of DIPROPYLENE GLYCOL DIBENZOATE:
Dipropylene glycol dibenzoate uses and applications include: Plasticizer for cellulosics, PVC, plastisols, PS, PVB, PVAc adhesives, VCA, castable PU; latex and lacquer coating applications; film-former, surfactant wetting agent in PVAc homopolymer emulsion adhesives; emollient in cosmetics; plasticizer for PVAc coatings for food-contact paperpaperboard; plasticizer for polymers in paperpaperboard in contact with dry food; in food packaging adhesives


Dipropylene glycol dibenzoate is used in PVC granule, non-filling rolling film, artificial leather, cable, board material, flaky material, pipe material, rubber bar, foam material, film, rubber and plastisol etc.
Dipropylene glycol dibenzoate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Other release to the environment of Dipropylene glycol dibenzoate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Release to the environment of Dipropylene glycol dibenzoate can occur from industrial use: in the production of articles, formulation of mixtures and in processing aids at industrial sites.
Release to the environment of Dipropylene glycol dibenzoate can occur from industrial use: manufacturing of the substance.


Other release to the environment of Dipropylene glycol dibenzoate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).


Dipropylene glycol dibenzoate can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), plastic (e.g. food packaging and storage, toys, mobile phones), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and rubber (e.g. tyres, shoes, toys).


Dipropylene glycol dibenzoate is used in the following products: lubricants and greases, adhesives and sealants, coating products, biocides (e.g. disinfectants, pest control products), plant protection products, polymers and fillers, putties, plasters, modelling clay.
Dipropylene glycol dibenzoate is used in the following areas: building & construction work and agriculture, forestry and fishing.


Dipropylene glycol dibenzoate is used for the manufacture of: machinery and vehicles and .
Dipropylene glycol dibenzoate is used in the following products: polymers, coating products, adhesives and sealants, inks and toners, cosmetics and personal care products, biocides (e.g. disinfectants, pest control products) and plant protection products.


Other release to the environment of Dipropylene glycol dibenzoate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).


Dipropylene glycol dibenzoate is used in the following products: adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, polymers, cosmetics and personal care products and lubricants and greases.
Release to the environment of Dipropylene glycol dibenzoate can occur from industrial use: formulation of mixtures and formulation in materials.


Dipropylene glycol dibenzoate is used in the following products: adhesives and sealants, coating products, lubricants and greases, inks and toners, fillers, putties, plasters, modelling clay, polymers and cosmetics and personal care products.
Dipropylene glycol dibenzoate is used in the following areas: building & construction work.


Dipropylene glycol dibenzoate is used for the manufacture of: machinery and vehicles and chemicals.
Release to the environment of Dipropylene glycol dibenzoate can occur from industrial use: in the production of articles, in processing aids at industrial sites and of substances in closed systems with minimal release.


Dipropylene glycol dibenzoate is used in the following applications:
Dipropylene glycol dibenzoate is used as an emollient due to its low toxicity profile and the fact that it confers a sophisticated talc like feel to products.


Dipropylene glycol dibenzoate is used as a solvent for many cosmetic actives, such as sunscreens and fragrances.
In antiperspirants and deodorants, Dipropylene glycol dibenzoate's humectant properties help to retain the natural moisture of hair as well as imparting considerable shine and body.


Dipropylene glycol dibenzoate is most commonly used in the packaging industry for carton sealing, book binding and labelling purposes and in the textile industry for woven as well as non-woven fabrics.
Plasticizers are organic compounds that are added to polymers (especially PVC) to facilitate processing and to increase flexibility and toughness of the final pruduct (brought about by an internal modification of the polymer molecule).


Dipropylene glycol dibenzoate is used in paste dispersions used in the manufacture of void fillers and buoyancy aids.
Dipropylene glycol dibenzoate can also be used as a coupling agent and moisturizer in a variety of different beauty cosmetic applications.
In the field of perfume, the proportion of Dipropylene glycol dibenzoate is more than 50%; In some other applications, the proportion of dipropylene glycol is generally less than 10% (by weight).


Some of the specific product application areas include: curling lotions, skin cleans (cold creams, body washes, body washes, and skin lotions) deodorants, face, hand, and body skin care products, moisturizing skin care products, and lip balms, among others.
Dipropylene glycol dibenzoate is a widely used plasticizer that has ether linkages linked with two benzoate groups.


Dipropylene glycol dibenzoate is used as a diluent for the preparation of polysulfone membranes by heat induced phase separation.
Dipropylene glycol dibenzoate finds potential applications in water treatment and food processing.
Dipropylene glycol dibenzoate may also be used as a plasticizer with poly(vinyl) chloride (PVC) for the fabrication of diamond coated PVC.


Dipropylene glycol dibenzoate is used Adhesives & Sealants, Agricultural Chemicals, Automotive Sealants, Crop Protection, Epoxy Coatings, Inks & Digital Inks, Nail Polish Remover, Plastic, Resin & Rubber, Textile Auxiliaries, Benzoates, Coatings, Copolymers, Leather, Paints, Pesticides, Plasticizers
Dipropylene glycol dibenzoate is used Caulk, Hair Care, Plastisol, Sunscreen, Vinyl Flooring


Dipropylene glycol dibenzoate is the most ideal solvent for many fragrance and cosmetic applications.
Dipropylene glycol dibenzoate has good water, oil and hydrocarbon co-solubility and mild odor, little skin irritation, low toxicity, uniform distribution of isomers, excellent quality.



MARKET SEGMENT OF DIPROPYLENE GLYCOL DIBENZOATE:
*Adhesives & Cements,
*Cosmetics & Personal Care,
*Plasticizers



FUNCTIONS OF DIPROPYLENE GLYCOL DIBENZOATE:
*Emollient :
Dipropylene glycol dibenzoate softens and smoothes the skin
*Skin conditioning :
Dipropylene glycol dibenzoate maintains skin in good condition



MARKETS OF DIPROPYLENE GLYCOL DIBENZOATE:
*Agriculture & Animal Care,
*CASE - Coatings,
*Adhesives,
*Sealants & Elastomers,
*Chemical & Materials Manufacturing,
*Textiles



WHAT DOES DIPROPYLENE GLYCOL DIBENZOATE DO IN A FORMULATION?
*Emollient
*Skin conditioning



PHYSICAL and CHEMICAL PROPERTIES of DIPROPYLENE GLYCOL DIBENZOATE:
Molar Mass: 326.39
Density: 1.144g/cm3
Boling Point: 464.198°C at 760 mmHg
Flash Point: 202.303°C
Vapor Presure: 0mmHg at 25°C
Storage Condition: Room Temprature
Refractive Index: 1.542
XLogP3: 4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 10
Exact Mass: 342.14672380 g/mol
Monoisotopic Mass: 342.14672380 g/mol
Topological Polar Surface Area: 61.8Ų
Decomposition temperature: > 270 °C
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility ca.0,00869 g/l at 20 °C slightly soluble

Partition coefficient: n-octanol/water: log Pow: 3,9 at 20 °C
Vapor pressure: No data available
Density: 1,12 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not explosive
Oxidizing properties: No data available
Other safety information:
Surface tension 59 mN/m at 20 °C
Molecular Formula: C20H22O5
Molecular Weight: 342.39
CAS Number: 27138-31-4
Catalog Number: 27138-31-4
Molecular Formula: C20H22O5
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 372
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: Clear & clean liquid
Assay: ≥99.0%
Acidity, as Benzoic: ≤0.1%
Color (APHA): ≤120
Hydroxyl No.: ≤6mg/g
Moisture: ≤0.07%
CAS No.: 27138-31-4
Molecular Formula: C20H22O5
InChIKeys: IZYUWBATGXUSIK-UHFFFAOYSA-N
Molecular Weight: 342.39
Exact Mass: 342.146729
EC Number: 248-258-5
HScode: 29163100
Categories: Other Food Additives
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 1.12000 @ 25.00 °C.
Refractive Index: 1.52800 @ 20.00 °C.
Boiling Point: 232.00 °C. @ 5.00 mm Hg
Boiling Point: 415.00 to 416.00 °C. @ 760.00 mm Hg (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )

logP (o/w): 4.702 (est)
Soluble in: water, 15 mg/L @ 25 °C (exp)
Physical state: viscous liquid
Color: colorless
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: 232 °C at 7 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 192 °C - closed cup - ASTM D 93
Autoignition temperature: > 400 °C at 1013 hPa
PSA: 61.83000
XLogP3: 6.45
Appearance: COA
Density: 1.1245 g/cm3 @ Temp: 20 °C
Boiling Point: 235 °C @ Press: 5 Torr
Flash Point: >230 °F
Refractive Index: 1.542
Vapor Pressure: 0mmHg at 25°C
Viscocity: 215 cp (20°C)
Appearance: Clear liquid
Specific Gravity at 25°C: 1.120
Boiling Point: 232°C
Odor: Faint,aromatic
Refractive Index: 1.528
Vapor Pressure: 0.0000012 mmHg (25°C)
Melting Point: -40°C
CAS#: 27138-31-4

Density: 1.120 (25C)
Fp (F): 390
Mw: 342
Physical Form: Liquid
Refractive Index: 1.528
Tm (C): -40
TSCA: TSCA listed
Viscosity: 215cp (20C)
Molecular Weight: 342.4 g/mol
XLogP3-AA: 4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 10
Exact Mass: 342.14672380 g/mol
Monoisotopic Mass: 342.14672380 g/mol
Topological Polar Surface Area: 61.8Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 372
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of DIPROPYLENE GLYCOL DIBENZOATE:
-Description of first-aid measures:
*General advice:
Consult a physician.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of DIPROPYLENE GLYCOL DIBENZOATE:
-Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
-Methods and materials for containment and cleaning up:
Soak up with inert absorbent material.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of DIPROPYLENE GLYCOL DIBENZOATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of DIPROPYLENE GLYCOL DIBENZOATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing.
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.



HANDLING and STORAGE of DIPROPYLENE GLYCOL DIBENZOATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of DIPROPYLENE GLYCOL DIBENZOATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Propanol, oxybis-, dibenzoate
Oxydipropyl dibenzoate
Oxybispropanol dibenzoate, bis (2-ethylhexyl) terephtalate
Dipropylene glycol dibenzoate
Benzoic acid diester with dipropylene glycol
Benzoic acid-n-dipropylene glycol diester
Dibenzoyl dipropylene glycol ester
Dipropanediol dibenzoate
3,3-Oxydi-1-propanol dibenzoate Oxydipropyl dibenzoate
3,3-Oxydyl-1-propanol dibenzoate
POP (2) dibenzoate
PPG-2 dibenzoate
PPG (2) dibenzoate
27138-31-4
94-03-1
Oxydipropyl dibenzoate
1,1'-Oxybis-2-propanol dibenzoate
1,1'-Dimethyl-2,2'-oxydiethyl dibenzoate
EINECS 202-296-9
UNII-9QQI0RSO3H
9QQI0RSO3H
2-Propanol, 1,1'-oxybis-, dibenzoate
Oxybis(propane-1,2-diyl) dibenzoate
1,1'-OXYBIS(2-PROPANOL) DIBENZOATE
DTXCID507921
DTXSID6027921
CAS-27138-31-4
1-(2-benzoyloxypropoxy)propan-2-yl benzoate
SCHEMBL1255193
CHEMBL1877406
DTXSID401043495
1,1'-Oxybis(2-propanol)dibenzoate
Tox21_202280
Tox21_300147
NCGC00164208-01
NCGC00247908-01
NCGC00254168-01
NCGC00259829-01
1,1'-oxybis(propane-2,1-diyl) dibenzoate
2-Propanol,1,1'-oxybis-,dibenzoate(9ci)
FT-0698140
2-PROPANOL, 1,1'-OXYDI-, DIBENZOATE
Q27272899
DI(1,2-PROPYLENE GLYCOL) DIBENZOATE, TAIL TO TAIL-
Polypropylene glycol (2) dibenzoate
PPG-2 Dibenzoate
Benzoflex 9-88
Finsolv PG 22
Oxybispropanol dibenzoate
Oxydipropyl dibenzoate
Propanol, oxybis-, dibenzoate
Dipropylene glycol, dibenzoate
Benzoflex 9-88 SG
Benzoflex 9-98
Dipropylene glycol dibenzoate
benzoic acid 3-(3-benzoyloxypropoxy)propyl ester
3,3'-Oxydipropyl dibenzoate
1-Propanol, 3,3'-oxybis-, dibenzoate
3-[3-(Benzoyloxy)propoxy]propyl benzoate
Di(propylene glycol) dibenzoate
1-Propanol, 3,3'-oxydi-, dibenzoate
3,3'-Oxybis(1-propanol) dibenzoate
3-[3-(phenylcarbonyloxy)propoxy]propyl benzoate
3-(3-benzoyloxypropoxy)propyl benzoate
dpgdb
oxybis-propanodibenzoate
oxydipropyl dibenzoate
oxydipropylenedibenzoate
benzoflex 284
dimethylolurea, tech
k-flex dp
dpg dibenzoate
dipropylenglycoldibenzoate
dipropanediol dibenzoate
Dibenzol dipropylene glycol ester
Dipropanediol dibenzoate
K-flex DP
[CHRIS] 1-[2-(Benzoyloxy)propoxy]propan-2-yl benzoate
Di(propylene glycol) dibenzoate
DPGDB
Benzoflex 9-88 SG
Propanol, oxybis-, dibenzoate
988SG
Di(propylene glycol) dibenzoate
Oxydi(propane-1,2-diyl) dibenzoate
2-Propanol, 1,1'-oxybis-, dibenzoate
27138-31-4
Dipropylene glycol dibenzoate (Propanol, oxybis-, dibenzoate)
Propanol, oxybis-, dibenzoate
Benzoflex 9088
Benzoflex 9-88
Benzoflex 9-88SG
Benzoflex 9-98
Dibenzoate d'oxydipropyle
dibenzoato de oxidipropilo
DIPROPYLENE GLYCOL DIBENZOATE
Dipropylene glycol, dibenzoate
DIPROPYLENGLYKOL-DIBENZOAT
Finsolv PG 22
K-Flex DP
Oxybispropanol dibenzoate
oxydipropyl dibenzoate
Oxydipropyldibenzoat
PPG 2 dibenzoate
EINECS 248-258-5
ADK Cizer PN 6120
Benzoflex 9-88
Benzoflex 9-88SG
Benzoflex 9-98
Benzoflex 9088
Benzoflex 988SG
BF 9-88
Finsolv PG 22
K-Flex DP
LS-E 97
Oxybispropanol dibenzoate
PN 6120
PPG 2 dibenzoate
Santicizer ER 9100
Synegis 9100
Propanol, oxybis-, dibenzoate
Oxydipropyl dibenzoate
Oxybispropanol dibenzoate, bis (2-ethylhexyl) terephtalate
Dipropyleneglycol dibenzoate
Propanol, oxybis-, dibenzoate
Di(propylene glycol) dibenzoate
Dipropanediol dibenzoate
PPG 2 dibenzoate
Oxydipropyl dibenzoate
Oxydi-3,1-propanediyl dibenzoate
Oxydipropane-3,1-diyl dibenzoate
BenzoflexTM9-88
K-Flex DP
Benzocizer 998
Dermel DPG-2B
DPGDB.
DPGDB
Oxydipropyl dibenzoate
Dipropylene glycol Dibenzoate
di(propylene glycol) dibenzoate
oxydipropane-3,1-diyl dibenzoate
oxydipropane-1,1-diyl dibenzoate
2-[1-(Benzoyloxy)propan-2-yloxy]propyl benzoate
DPGDB; Oxydipropyl Dibenzoate
Benzoic Acid N-Dipropylene Glycol Diester
Dipropanediol Dibenzoate
1-((1-(Benzoyloxy)propan-2-yl)oxy)propan-2-yl benzoate
1-Propanol, 1,1'-oxybis-, dibenzoate
988SG
ADK Cizer PN 6120
Benzoflex 9088
Benzoflex 9-88
Benzoflex 988SG
Benzoflex 9-88SG
Benzoflex 9-98
Di(propylene glycol) dibenzoate
DIMETHYLOLUREA,TECH
DIPROPANEDIOL DIBENZOATE
Dipropylene glycol dibenzoate
Dipropylene glycol, dibenzoate
Dipropylenglycoldibenzoate
DPG dibenzoate
DPGDB
EINECS 248-258-5
Finsolv PG 22
K-Flex DP
LS-E 97
MFCD00046063
oxybis-propanodibenzoate
Oxybispropanol dibenzoate
Oxydi-1,1-propanediyl dibenzoate
Oxydipropane-1,1-diyl dibenzoate
OXYDIPROPYLENEDIBENZOATE
PN 6120
Polycizer DP 500
PPG 2 dibenzoate
Propanol, oxybis-, dibenzoate
Propanol,oxybis-,dibenzoate
Santicizer ER 9100
Synegis 9100
UNII-6OA5ZDY41O
3,3'-OXYDI-1-PROPANOL DIBENZOATE
BENZOIC ACID N-DIPROPYLENEGLYCOL DIESTER
DIPROPANEDIOL DIBENZOATE
DIPROPYLENE GLYCOL DIBENZOATE
DPGDB
K-FLEX DP
Dipropylenglycoldibenzoate
oxybis-propanodibenzoate
Propanol,oxybis-,dibenzoate
oxydipropyl dibenzoate
DI(PROPYLENE GLYCOL) DIBENZOATE, TECH.,&
3 3-OXYDI-L-PROPANOL DIBENZOATE
DPGDBFDA:21CFR175.105,176.170and176.180
DPG dibenzoate
OXYDIPROPYLENEDIBENZOATE
DI12PROPYLENEGLYCOLDIBENZOATE
Reaktionsprodukt aus 1,2-Dipropylenglykol mit Benzoesure
2-[1-(Benzoyloxy)propan-2-yloxy]propyl benzoate



DIPROPYLENE GLYCOL DIBENZOATE
Dipropylene Glycol Dibenzoate is a diester of polypropylene glycol and benzoic acid.
Dipropylene Glycol Dibenzoate is a polar, high-solvating plasticizer.
Dipropylene Glycol Dibenzoate is compatible with a wide range of polar polymers and rubbers.


CAS Number: 27138-31-4 / 94-51-9
EC Number: 248-258-5
Chem/IUPAC Name: Oxydipropyl dibenzoate
Linear Formula: (C6H5CO2C3H6)2O



Polypropylene glycol (2) dibenzoate, PPG-2 Dibenzoate, Benzoflex 9-88, Finsolv PG 22, Oxybispropanol dibenzoate, Oxydipropyl dibenzoate, Propanol, oxybis-, dibenzoate, Dipropylene glycol, dibenzoate, [ChemIDplus] Benzoflex 9-88 SG, Benzoflex 9-98, Dibenzol dipropylene glycol ester, Dipropanediol dibenzoate, K-flex DP, [CHRIS] 1-[2-(Benzoyloxy)propoxy]propan-2-yl benzoate, [ECHA REACH Registrations] Di(propylene glycol) dibenzoate, Propanol, oxybis-, dibenzoate, Oxydipropyl dibenzoate, Oxybispropanol dibenzoate, bis (2-ethylhexyl) terephtalate, DPGDB, Benzoflex™ 9-88 SG, Propanol, oxybis-, dibenzoate, 988SG, ADK Cizer PN 6120, Benzoflex 9-88, Benzoflex 9-88SG, Benzoflex 9-98, Benzoflex 9088, Benzoflex 988SG, BF 9-88, Finsolv PG 22, K-Flex DP, LS-E 97, Oxybispropanol dibenzoate, PN 6120, PPG 2 dibenzoate, Santicizer ER 9100, Synegis 9100, Benzoate ester,Propanol, oxybis, dibenzoate,Dipropylene glycol dibenzoate,PPG-2 Dibenzoate,Polypropylene glycol (2) dibenzoate,Oxydipropyl, dibenzoate,Propanol, oxybis-, dibenzoate, staramine,OXYBISPROPANOL,DIBENZOATE,BYQDGAVOOHIJQS-UHFFFAOYSA-N,3,3'-oxydipropyl dibenzoate,DI13PROPYLENEGLYCOLDIBENZOATE,3,3'-Oxybis(1-propanol)dibenzoate,Oxybis(trimethylene) bis[benzoate],1-Propanol, 3,3-oxybis-, dibenzoate,3-[3-(benzoyloxy)propoxy]propyl benzoate,1-Propanol, 3,3'-oxybis-, 1,1'-dibenzoate, DPGDB, Benzoflex 9-88 SG, Propanol, oxybis-, dibenzoate, 988SG, ADK Cizer PN 6120, Benzoflex 9-88, Benzoflex 9-88SG, Benzoflex 9-98, Benzoflex 9088, Benzoflex 988SG, BF 9-88, Finsolv PG 22, K-Flex DP, LS-E 97, Oxybispropanol dibenzoate, PN 6120, PPG 2 dibenzoate, Santicizer ER 9100, Synegis 9100,



Dipropylene Glycol Dibenzoate is an oily liquid that makes your skin nice and smooth (aka emollient).
Dipropylene Glycol Dibenzoate is also claimed to have some humectant and moisturizing properties without a greasy after-feel.
But its real superpower is being an outstanding solvent for hard to solubilize sunscreen agents (that is most of the chemical sunscreen filters) making


Dipropylene Glycol Dibenzoate an excellent emollient choice in high SPF products.
Dipropylene Glycol Dibenzoate is a polar, high-solvating plasticizer.
Dipropylene Glycol Dibenzoate is compatible with a wide range of polar polymers and rubbers.


Dipropylene Glycol Dibenzoate is dipropylene glycol dibenzoate.
Dipropylene Glycol Dibenzoate is a polar, high-solvating plasticizer.
Dipropylene Glycol Dibenzoate is compatible with a wide range of polar polymers and rubbers.


Dipropylene Glycol Dibenzoate is a polar, high-solvating plasticizers. Dipropylene Glycol Dibenzoate is compatible with a wide range of
polar polymers and rubbers.
Dipropylene Glycol Dibenzoate is useful in applications such as latex caulks, adhesive, and sealants, coatings and vinyl plastisols.


Dipropylene Glycol Dibenzoate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Dipropylene Glycol Dibenzoate is an oily liquid that makes your skin nice and smooth (aka emollient).


Dipropylene Glycol Dibenzoate is also claimed to have some humectant and moisturizing properties without a greasy after-feel.
But its real superpower is being an outstanding solvent for hard to solubilize sunscreen agents (that is most of the chemical sunscreen filters) making Dipropylene Glycol Dibenzoate an excellent emollient choice in high SPF products.


Dipropylene Glycol Dibenzoate is a polar, high-solvating plasticizer.
Dipropylene Glycol Dibenzoate is compatible with a wide range of polar polymers and rubbers.
Dipropylene Glycol Dibenzoate is useful in applications such as latex caulks, adhesive, and sealants, coatings and vinyl plastisols.


Dipropylene Glycol Dibenzoate is dipropylene glycol dibenzoate. It is a polar, high-solvating plasticizer.
Dipropylene Glycol Dibenzoate is compatible with a wide range of polar polymers and rubbers.
Dipropylene Glycol Dibenzoate is a polar, high-solvating plasticizers.


Dipropylene Glycol Dibenzoate is compatible with a wide range of polar polymers and rubbers.
Dipropylene Glycol Dibenzoate is useful in applications such as latex caulks, adhesive, and sealants, coatings and vinyl plastisols.
Dipropylene Glycol Dibenzoate is a straw-colored viscous liquid with faint aromatic odor.



USES and APPLICATIONS of DIPROPYLENE GLYCOL DIBENZOATE:
Dipropylene Glycol Dibenzoate is used as a solvator for PVC, plasticizer in elastomers, in vinyl flooring, adhesives, latex caulks and sealants, color concentrates for PVC, and castable polyurethanes.
Dipropylene Glycol Dibenzoate is used Adhesives & Sealants, Agricultural Chemicals, Automotive Sealants, Crop Protection, Epoxy Coatings, Inks & Digital Inks, Nail Polish Remover, Plastic, Resin & Rubber, Textile Auxiliaries, Benzoates, Coatings, Copolymers, Leather, Paints, Pesticides, Plasticizers.


Dipropylene Glycol Dibenzoate is used in PVC granule, non-filling rolling film, artificial leather, cable, board material, flaky material, pipe material, rubber bar, foam.
Dipropylene Glycol Dibenzoate is Straw-colored viscous liquid with faint aromatic odor.


Dipropylene Glycol Dibenzoate is used as a solvator for PVC, plasticizer in elastomers, in vinyl flooring, adhesives, latex caulks and sealants, color concentrates for PVC, and castable polyurethanes.
Dipropylene Glycol Dibenzoate is used in the following areas: building & construction work.


Dipropylene Glycol Dibenzoate is used for the manufacture of: machinery and vehicles and chemicals.
Dipropylene Glycol Dibenzoate is used to formulate adhesives, sealants, lubricants, plasticizers, coatings, and inks, to make fine and large scale chemicals, and as a plasticizer for PVC and carrier for agrochemicals.


Dipropylene Glycol Dibenzoate is permitted for use as an inert ingredient in non-food pesticide products.
As a highly soluble benzoate plasticizer, Dipropylene Glycol Dibenzoate is characterized by low toxicity and environmental protection, low gelling temperature, high plasticizing efficiency, large filling amount, good cold resistance and pollution resistance.


Dipropylene Glycol Dibenzoate has been recognized and recommended by the European Union to replace the conventional chemicalbook o-benzene plasticizer and used as an environmental protection plasticizer.
Dipropylene Glycol Dibenzoate is widely used in PVC synthetic plastics, water-based adhesive, polysulfide sealant, polyurethane sealant, artificial leather and synthetic rubber, and reflects its superior performance and plasticizing effect.


Dipropylene Glycol Dibenzoate is useful in applications such as latex caulks, adhesive, and sealants, coatings and vinyl plastisols.
Dipropylene Glycol Dibenzoate is used as a solvator for PVC, plasticizer in elastomers, in vinyl flooring, adhesives, latex caulks and sealants, color concentrates for PVC, and castable polyurethanes.


Dipropylene Glycol Dibenzoate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Dipropylene Glycol Dibenzoate is used in applications such as latex caulks, adhesives and sealants.


Dipropylene Glycol Dibenzoate is used in the following products: polymers, coating products, adhesives and sealants, inks and toners, cosmetics and personal care products, biocides (e.g. disinfectants, pest control products) and plant protection products.
Dipropylene Glycol Dibenzoate is permitted for use as an inert ingredient in non-food pesticide products.


Other release to the environment of Dipropylene Glycol Dibenzoate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Release to the environment of Dipropylene Glycol Dibenzoate can occur from industrial use: in the production of articles, formulation of mixtures and in processing aids at industrial sites.
Dipropylene Glycol Dibenzoate is used for the manufacture of: machinery and vehicles and .


Other release to the environment of Dipropylene Glycol Dibenzoate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).


Dipropylene Glycol Dibenzoate can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), plastic (e.g. food packaging and storage, toys, mobile phones), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and rubber (e.g. tyres, shoes, toys).


Dipropylene Glycol Dibenzoate is used in the following products: lubricants and greases, adhesives and sealants, coating products, biocides (e.g. disinfectants, pest control products), plant protection products, polymers and fillers, putties, plasters, modelling clay.
Dipropylene Glycol Dibenzoate is used in the following areas: building & construction work and agriculture, forestry and fishing.


Other release to the environment of Dipropylene Glycol Dibenzoate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).


Dipropylene Glycol Dibenzoate is used in the following products: adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, polymers, cosmetics and personal care products and lubricants and greases.
Release to the environment of Dipropylene Glycol Dibenzoate can occur from industrial use: formulation of mixtures and formulation in materials.


Dipropylene Glycol Dibenzoate is used in the following products: adhesives and sealants, coating products, lubricants and greases, inks and toners, fillers, putties, plasters, modelling clay, polymers and cosmetics and personal care products.
Dipropylene Glycol Dibenzoate is used in the following areas: building & construction work.


Dipropylene Glycol Dibenzoate is used for the manufacture of: machinery and vehicles and chemicals.
Release to the environment of Dipropylene Glycol Dibenzoate can occur from industrial use: in the production of articles, in processing aids at industrial sites and of substances in closed systems with minimal release.


Release to the environment of Dipropylene Glycol Dibenzoate can occur from industrial use: manufacturing of the substance.
Dipropylene Glycol Dibenzoate is used as a solvator for PVC, plasticizer in elastomers, in vinyl flooring, adhesives, latex caulks and sealants, color concentrates for PVC, and castable polyurethanes.


Dipropylene Glycol Dibenzoate is used to formulate adhesives, sealants, lubricants, plasticizers, coatings, and inks, to make fine and large scale chemicals, and as a plasticizer for PVC and carrier for agrochemicals.
Dipropylene Glycol Dibenzoate is permitted for use as an inert ingredient in non-food pesticide products.


Dipropylene Glycol Dibenzoate is used as a highly soluble benzoate plasticizer, is characterized by low toxicity and environmental protection, low gelling temperature, high plasticizing efficiency, large filling amount, good cold resistance and pollution resistance.
Dipropylene Glycol Dibenzoate has been recognized and recommended by the European Union to replace the conventional chemicalbook o-benzene plasticizer and used as an environmental protection plasticizer.


Dipropylene Glycol Dibenzoate is widely used in PVC synthetic plastics, water-based adhesive, polysulfide sealant, polyurethane sealant, artificial leather and synthetic rubber, and reflects its superior performance and plasticizing effect.
Dipropylene Glycol Dibenzoate is used in applications such as latex caulks, adhesives and sealants.


Dipropylene Glycol Dibenzoate is used as a solvator for PVC, plasticizer in elastomers, in vinyl flooring, adhesives, latex caulks and sealants, color concentrates for PVC, and castable polyurethanes.
Dipropylene Glycol Dibenzoate is used Adhesives & Sealants, Agricultural Chemicals, Automotive Sealants, Crop Protection, Epoxy Coatings, Inks & Digital Inks, Nail Polish Remover, Plastic, Resin & Rubber, Textile Auxiliaries, Benzoates, Coatings, Copolymers, Leather, Paints, Pesticides, Plasticizers


Dipropylene Glycol Dibenzoate is used in PVC granule, non-filling rolling film, artificial leather, cable, board material, flaky material, pipe material, rubber bar, foam
Dipropylene Glycol Dibenzoate is used as a solvator for PVC, plasticizer in elastomers, in vinyl flooring, adhesives, latex caulks and sealants, color concentrates for PVC, and castable polyurethanes.



WHAT DOES DIPROPYLENE GLYCOL DIBENZOATE DO IN A FORMULATION?
*Emollient
*Skin conditioning



REACTIVITY PROFILE OF DIPROPYLENE GLYCOL DIBENZOATE:
Dipropylene Glycol Dibenzoate is an ester.
Esters react with acids to liberate heat along with alcohols and acids.
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products.
Heat is also generated by the interaction of esters with caustic solutions.



PHYSICAL and CHEMICAL PROPERTIES of DIPROPYLENE GLYCOL DIBENZOATE:
Molecular Weight: 342.4 g/mol
XLogP3-AA: 4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 10
Exact Mass: 342.14672380 g/mol
Monoisotopic Mass: 342.14672380 g/mol
Topological Polar Surface Area: 61.8Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 372
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 1.12000 @ 25.00 °C.
Refractive Index: 1.52800 @ 20.00 °C.
Boiling Point: 232.00 °C. @ 5.00 mm Hg
Boiling Point: 415.00 to 416.00 °C. @ 760.00 mm Hg (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 4.702 (est)
Soluble in: water, 15 mg/L @ 25 °C (exp)
Physical state: viscous liquid
Color: colorless
Odor: No data available

Melting point/freezing point: No data available
Initial boiling point and boiling range: 232 °C at 7 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 192 °C - closed cup - ASTM D 93
Autoignition temperature: > 400 °C at 1013 hPa
Decomposition temperature: > 270 °C
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility ca.0,00869 g/l at 20 °C slightly soluble
Partition coefficient: n-octanol/water: log Pow: 3,9 at 20 °C
Vapor pressure: No data available
Density: 1,12 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not explosive
Oxidizing properties: No data available
Other safety information:
Surface tension 59 mN/m at 20 °C
Molecular Formula: C20H22O5
Molecular Weight: 342.39
CAS Number: 27138-31-4

Catalog Number: 27138-31-4
Molecular Formula: C20H22O5
Molar Mass: 326.39
Density: 1.144g/cm3
Boling Point: 464.198°C at 760 mmHg
Flash Point: 202.303°C
Vapor Presure: 0mmHg at 25°C
Storage Condition: Room Temprature
Refractive Index: 1.542
XLogP3: 4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 10
Exact Mass: 342.14672380 g/mol
Monoisotopic Mass: 342.14672380 g/mol
Topological Polar Surface Area: 61.8Ų

Heavy Atom Count: 25
Formal Charge: 0
Complexity: 372
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: Clear & clean liquid
Assay: ≥99.0%
Acidity, as Benzoic: ≤0.1%
Color (APHA): ≤120
Hydroxyl No.: ≤6mg/g
Moisture: ≤0.07%
Assay: 95.00 to 100.00

Food Chemicals Codex Listed: No
Specific Gravity: 1.12000 @ 25.00 °C.
Refractive Index: 1.52800 @ 20.00 °C.
Boiling Point: 232.00 °C. @ 5.00 mm Hg
Boiling Point: 415.00 to 416.00 °C. @ 760.00 mm Hg (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 4.702 (est)
Soluble in: water, 15 mg/L @ 25 °C (exp)
IUPAC Name: 1-(2-benzoyloxypropoxy)propan-2-yl benzoate
Canonical SMILES: CC(COCC(C)OC(=O)C1=CC=CC=C1)OC(=O)C2=CC=CC=C2
InChI: InChI=1S/C20H22O5/c1-15(24-19(21)17-9-5-3-6-10-17)13-23-14-16(2)25-20(22)18-11-7-4-8-12-18/h3-12,15-16H,13-14H2,1-2H3
InChI Key: IZYUWBATGXUSIK-UHFFFAOYSA-N
Boiling Point: 235°C
Flash Point: 377.6 °F
Purity: 95%
Density: 1.1245 g/cm3
Appearance: Pale Yellow Liquid

XLogP3: 4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 10
Exact Mass: 342.14672380 g/mol
Monoisotopic Mass: 342.14672380 g/mol
Topological Polar Surface Area: 61.8Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 372
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of DIPROPYLENE GLYCOL DIBENZOATE:
-Description of first-aid measures:
*General advice:
Consult a physician.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of DIPROPYLENE GLYCOL DIBENZOATE:
-Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
-Methods and materials for containment and cleaning up:
Soak up with inert absorbent material.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of DIPROPYLENE GLYCOL DIBENZOATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of DIPROPYLENE GLYCOL DIBENZOATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing.
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.



HANDLING and STORAGE of DIPROPYLENE GLYCOL DIBENZOATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of DIPROPYLENE GLYCOL DIBENZOATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

DIPROPYLENE GLYCOL DIBENZOATE
Dipropylene Glycol Dibenzoate is a diester of polypropylene glycol and benzoic acid.
Dipropylene Glycol Dibenzoate is viscous straw-colored liquid with a faint odor.



CAS Number: 27138-31-4 / 94-51-9
EC Number: 248-258-5
Chem/IUPAC Name: Oxydipropyl dibenzoate
Linear Formula: (C6H5CO2C3H6)2O


Dipropylene Glycol Dibenzoate is a colorless liquid with a mild ester odor.
Dipropylene Glycol Dibenzoate is a non-phthalate plasticizer specifically designed for 2K polyurethane systems where it is very compatible and efficient.
Dipropylene Glycol Dibenzoate is a highly soluble benzoate plasticizer, and its main component is dipropylene glycol dibenzoate.



USES and APPLICATIONS of DIPROPYLENE GLYCOL DIBENZOATE:
Dipropylene Glycol Dibenzoate is used as a solvator for PVC, plasticizer in elastomers, in vinyl flooring, adhesives, latex caulks and sealants, color concentrates for PVC, and castable polyurethanes.
Dipropylene Glycol Dibenzoate is used to formulate adhesives, sealants, lubricants, plasticizers, coatings, and inks, to make fine and large scale chemicals, and as a plasticizer for PVC and carrier for agrochemicals.


As an alternative to o-benzene plasticizers recommended by the EU, as an environmentally friendly plasticizer, Dipropylene Glycol Dibenzoate is widely used in water-based adhesives (white latex, woodworking glue, plywood glue, paper packaging glue, laminating glue, smoke glue, etc.), polysulfide sealants, polyurethane sealants, caulking agents, PVC products (toys, elastic floors, gloves, PVC plastic-impregnated products, Teslin, water hoses, artificial leather, etc.), polyurethane elastomers/rubber rollers, coatings, inks, pesticides, fluorescent materials and other fields.
ropylene Glycol Dibenzoate finds potential applications in water treatment and food processing.


Dipropylene Glycol Dibenzoate is mainly used as plasticizer, for example, used in resilient floors, plastisol, adhesives, binder, coatings and coated materials,screen printing ink, sealants, filler and caulking materials, dyes, nail polish, skin protect product, photoresist, liquid crystal film, polymer of disposable hygiene products and food packaging, etc.


Dipropylene Glycol Dibenzoate can be plasticized such as PVC, polyethylene/polypropylene, polyvinyl aceate£¬polystyrene, polyvinyl alcohol, polyvinyl butyral, polymethacrylate, polyisocyanate, polyurethane, phenolic resins, epoxy resins, polyether, ethylcellulose, cellulose butyrate, nitrocellulose, chloroethylene or ethylene-vinyl acetate copolymer, styrene-acrylate copolymer, ethylene-maleic anhydride copolymer, and so on.


In addition, Dipropylene Glycol Dibenzoate is also as processing aid of natural or synthetic rubber, solubilizer and dispersant of pigments or toner, and as extractive distillation agent for the organics that their boiling points is proximity.
Dipropylene Glycol Dibenzoate is used for Plasticizer for plastics. Dibenzoate plasticizers are mainly used in PVA (polyvinyl acetate) emulsion adhesives, caulking agents, sealants, coatings.


Performance and use dipropylene glycol dibenzoate as a highly soluble benzoate plasticizer, because of its low toxicity and environmental protection, low solization temperature, high plasticizing efficiency, large filling volume, cold resistance, good pollution resistance and other characteristics.
It is recognized and recommended by the European Union to replace conventional o-benzene plasticizers and Dipropylene Glycol Dibenzoate is used as environmentally friendly plasticizers.


Dipropylene Glycol Dibenzoate is widely used in polyvinyl chloride synthetic plastics, water-based adhesives, polysulfide sealants, polyurethane sealants, and artificial leather And synthetic rubber and other fields, and reflect its superiority and plasticizing effect.
Dipropylene Glycol Dibenzoate can be used as a plasticizer for resins such as polyvinyl chloride, polyvinyl acetate and polyurethane.


Dipropylene Glycol Dibenzoate has strong solvent effect, good compatibility, low volatility, durability, oil resistance and pollution resistance.
Dipropylene Glycol Dibenzoate is also excellent.
Dipropylene Glycol Dibenzoate is often used for highly filled PVC flooring and extruded plastics, which can improve processability, reduce processing temperature and shorten processing cycle.


When Dipropylene Glycol Dibenzoate is used in non-filled films, sheets and pipes, the transparency and surface gloss of the product are good.
Dipropylene Glycol Dibenzoate is used as a solvator for PVC, plasticizer in elastomers, in vinyl flooring, adhesives, latex caulks and sealants, color concentrates for PVC, and castable polyurethanes.


Dipropylene Glycol Dibenzoate is used as a highly soluble benzoate plasticizer, is characterized by low toxicity and environmental protection, low gelling temperature, high plasticizing efficiency, large filling amount, good cold resistance and pollution resistance.
Dipropylene Glycol Dibenzoate is permitted for use as an inert ingredient in non-food pesticide products.


Dipropylene Glycol Dibenzoate has been recognized and recommended by the European Union to replace the conventional chemicalbook o-benzene plasticizer and used as an environmental protection plasticizer.
Cosmetic Uses of Dipropylene Glycol Dibenzoate: skin conditioning, and skin conditioning - emollient


Dipropylene Glycol Dibenzoate is widely used in PVC synthetic plastics, water-based adhesive, polysulfide sealant, polyurethane sealant, artificial leather and synthetic rubber, and reflects its superior performance and plasticizing effect.
Dipropylene Glycol Dibenzoate may also be used as a plasticizer with poly(vinyl) chloride (PVC) for the fabrication of diamond coated PVC.



PROPERTIES OF DIPROPYLENE GLYCOL DIBENZOATE:
Dipropylene Glycol Dibenzoate is a transparent oily liquid of colorless to yellow.
Dipropylene Glycol Dibenzoate is soluble in aliphatic hydrocarbons and aromatic hydrocarbons, insoluble in water.



WHAT DOES DIPROPYLENE GLYCOL DIBENZOATE DO IN A FORMULATION?
*Emollient
*Skin conditioning



FUNCTIONS OF DIPROPYLENE GLYCOL DIBENZOATE:
*Emollient:
Dipropylene Glycol Dibenzoate softens and softens the skin
*Skin conditioning agent:
Dipropylene Glycol Dibenzoate keeps the skin in good condition



PHYSICAL and CHEMICAL PROPERTIES of DIPROPYLENE GLYCOL DIBENZOATE:
Molecular Weight: 342.4 g/mol
XLogP3-AA: 4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 10
Exact Mass: 342.14672380 g/mol
Monoisotopic Mass: 342.14672380 g/mol
Topological Polar Surface Area: 61.8Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 372
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 1.12000 @ 25.00 °C.
Refractive Index: 1.52800 @ 20.00 °C.
Boiling Point: 232.00 °C. @ 5.00 mm Hg
Boiling Point: 415.00 to 416.00 °C. @ 760.00 mm Hg (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 4.702 (est)
Soluble in: water, 15 mg/L @ 25 °C (exp)
Physical state: viscous liquid
Color: colorless
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: 232 °C at 7 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 192 °C - closed cup - ASTM D 93
Autoignition temperature: > 400 °C at 1013 hPa

Decomposition temperature: > 270 °C
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility ca.0,00869 g/l at 20 °C slightly soluble
Partition coefficient: n-octanol/water: log Pow: 3,9 at 20 °C
Vapor pressure: No data available
Density: 1,12 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not explosive
Oxidizing properties: No data available
Other safety information:
Surface tension 59 mN/m at 20 °C
Molecular Formula: C20H22O5
Molecular Weight: 342.39
CAS Number: 27138-31-4
Catalog Number: 27138-31-4
Molecular Formula: C20H22O5

Molar Mass: 326.39
Density: 1.144g/cm3
Boling Point: 464.198°C at 760 mmHg
Flash Point: 202.303°C
Vapor Presure: 0mmHg at 25°C
Storage Condition: Room Temprature
Refractive Index: 1.542
XLogP3: 4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 10
Exact Mass: 342.14672380 g/mol
Monoisotopic Mass: 342.14672380 g/mol
Topological Polar Surface Area: 61.8Ų

Heavy Atom Count: 25
Formal Charge: 0
Complexity: 372
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: Clear & clean liquid
Assay: ≥99.0%
Acidity, as Benzoic: ≤0.1%
Color (APHA): ≤120
Hydroxyl No.: ≤6mg/g
Moisture: ≤0.07%



FIRST AID MEASURES of DIPROPYLENE GLYCOL DIBENZOATE:
-Description of first-aid measures:
*General advice:
Consult a physician.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of DIPROPYLENE GLYCOL DIBENZOATE:
-Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
-Methods and materials for containment and cleaning up:
Soak up with inert absorbent material.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of DIPROPYLENE GLYCOL DIBENZOATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of DIPROPYLENE GLYCOL DIBENZOATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing.
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.



HANDLING and STORAGE of DIPROPYLENE GLYCOL DIBENZOATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of DIPROPYLENE GLYCOL DIBENZOATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
27138-31-4
94-03-1
Oxydipropyl dibenzoate
1,1'-Oxybis-2-propanol dibenzoate
1,1'-Dimethyl-2,2'-oxydiethyl dibenzoate
EINECS 202-296-9
UNII-9QQI0RSO3H
9QQI0RSO3H
2-Propanol, 1,1'-oxybis-, dibenzoate
Oxybis(propane-1,2-diyl) dibenzoate
1,1'-OXYBIS(2-PROPANOL) DIBENZOATE
DTXCID507921
DTXSID6027921
CAS-27138-31-4
1-(2-benzoyloxypropoxy)propan-2-yl benzoate
SCHEMBL1255193
CHEMBL1877406
DTXSID401043495
1,1'-Oxybis(2-propanol)dibenzoate
Tox21_202280
Tox21_300147
NCGC00164208-01
NCGC00247908-01
NCGC00254168-01
NCGC00259829-01
1,1'-oxybis(propane-2,1-diyl) dibenzoate
2-Propanol,1,1'-oxybis-,dibenzoate(9ci)
FT-0698140
2-PROPANOL, 1,1'-OXYDI-, DIBENZOATE
Q27272899
DI(1,2-PROPYLENE GLYCOL) DIBENZOATE, TAIL TO TAIL-
Polypropylene glycol (2) dibenzoate
PPG-2 Dibenzoate
Benzoflex 9-88
Finsolv PG 22
Oxybispropanol dibenzoate
Oxydipropyl dibenzoate
Propanol, oxybis-, dibenzoate
Dipropylene glycol, dibenzoate
Benzoflex 9-88 SG
Benzoflex 9-98
Dibenzol dipropylene glycol ester
Dipropanediol dibenzoate
K-flex DP
[CHRIS] 1-[2-(Benzoyloxy)propoxy]propan-2-yl benzoate
Di(propylene glycol) dibenzoate
DPGDB
Benzoflex 9-88 SG
Propanol, oxybis-, dibenzoate
988SG
ADK Cizer PN 6120
Benzoflex 9-88
Benzoflex 9-88SG
Benzoflex 9-98
Benzoflex 9088
Benzoflex 988SG
BF 9-88
Finsolv PG 22
K-Flex DP
LS-E 97
Oxybispropanol dibenzoate
PN 6120
PPG 2 dibenzoate
Santicizer ER 9100
Synegis 9100
Propanol, oxybis-, dibenzoate
Oxydipropyl dibenzoate
Oxybispropanol dibenzoate, bis (2-ethylhexyl) terephtalate
Dipropyleneglycol dibenzoate
Propanol, oxybis-, dibenzoate
Di(propylene glycol) dibenzoate
Dipropanediol dibenzoate
PPG 2 dibenzoate
Oxydipropyl dibenzoate
Oxydi-3,1-propanediyl dibenzoate
Oxydipropane-3,1-diyl dibenzoate
BenzoflexTM9-88
K-Flex DP
Benzocizer 998
Dermel DPG-2B
DPGDB.
DPGDB
Oxydipropyl dibenzoate
Dipropylene glycol Dibenzoate
di(propylene glycol) dibenzoate
oxydipropane-3,1-diyl dibenzoate
oxydipropane-1,1-diyl dibenzoate
2-[1-(Benzoyloxy)propan-2-yloxy]propyl benzoate


DIPROPYLENE GLYCOL DIBENZOATE (DPGDB)
Dipropylene glycol dibenzoate (DPGDB)'s linear formula is (C6H5CO2C3H6)2O.
With a CAS number of 27138-31-4 and an EC number of 248-258-5, Dipropylene glycol dibenzoate (DPGDB) is widely recognized for its versatility and performance.


CAS Number: 27138-31-4
EC Number: 248-258-5
Linear Formula: (C6H5CO2C3H6)2O
Molecular Formula: C20H22O5



Dipropyleneglycol dibenzoate, Propanol, oxybis-, dibenzoate, Di(propylene glycol) dibenzoate, Dipropanediol dibenzoate, PPG 2 dibenzoate, Oxydipropyl dibenzoate, Oxydi-3,1-propanediyl dibenzoate, Oxydipropane-3,1-diyl dibenzoate, BenzoflexTM9-88, K-Flex DP, Benzocizer 998, Dermel DPG-2B, DPGDB.
2,2'-Oxydipropyl dibenzoate, 2-[1-(Benzoyloxy)propan-2-yloxy]propyl benzoate, BENZOIC ACID N-DIPROPYLENEGLYCOL DIESTER, K-FLEX DP, DIPROPYLENE GLYCOL DIBENZOATE, DIPROPANEDIOL DIBENZOATE, DPGDB, 3,3'-OXYDI-1-PROPANOL DIBENZOATE, Dipropylenglycoldibenzoate, oxybis-propanodibenzoate, DPGDB, Oxydipropyl dibenzoate, 2-[1-(Benzoyloxy)propan-2-yloxy]propyl benzoate, oxydipropane-3,1-diyl dibenzoate, Dipropylene glycol Dibenzoate, oxydipropane-1,1-diyl dibenzoate, Dipropyleneglycol dibenzoate, Propanol, oxybis-, dibenzoate, Di(propylene glycol) dibenzoate, Dipropanediol dibenzoate, PPG 2 dibenzoate, Oxydipropyl dibenzoate, Oxydi-3,1-propanediyl dibenzoate, Oxydipropane-3,1-diyl dibenzoate, BenzoflexTM9-88, K-Flex DP, Benzocizer®998, Dermel DPG-2B, DPGDB,



Dipropylene glycol dibenzoate (DPGDB) is a transparent oily liquid of colorless to yellow.
Dipropylene glycol dibenzoate (DPGDB) soluble in aliphatic hydrocarbons and aromatic hydrocarbons, insoluble in water.
Dipropylene glycol dibenzoate (DPGDB) is haplotype and Strong solvent based plasticizer.


Dipropylene glycol dibenzoate (DPGDB) has light ill-smelling.
Dipropylene glycol dibenzoate (DPGDB) can be compatible with lots of polymer,very faster dissolves vinyl resins.
Dipropylene glycol dibenzoate (DPGDB) can reduce the melting temperature and reduce production time.


Dipropylene glycol dibenzoate (DPGDB) is resistant to mineral oil extract and has high flash point no peculiar odor.
Dipropylene glycol dibenzoate (DPGDB) has no harm of touch, has a good compatibility with resins.
Dipropylene glycol dibenzoate (DPGDB) can retain the foam structure of tiny when producing opening vinyl foam.


Foam products are very soft, Dipropylene glycol dibenzoate (DPGDB) is pore uniformity similar to soft leather.
Dipropylene glycol dibenzoate (DPGDB) be made into vinyl flooring can not be infiltration and pollution by asphalt.
Dipropylene glycol dibenzoate (DPGDB) is haplotype and Strong solvent based plasticizer.


Dipropylene glycol dibenzoate (DPGDB) can be compatible with lots of polymer,very faster dissolve vinyl resins. can reduce the melting temperature and reduce production time.
Dipropylene glycol dibenzoate (DPGDB) is resistant to mineral oil extract and have high flash point no peculiar odor.


Dipropylene glycol dibenzoate (DPGDB) can retain the foam structure of tiny when produce opening vinyl foam.
Dipropylene glycol dibenzoate (DPGDB) be made into vinyl flooring can not be infiltration and pollution by asphalt.
Dipropylene glycol dibenzoate (DPGDB) is a high solvating Dibenzoate plasticizer.


Dipropylene glycol dibenzoate (DPGDB) acts as a plasticizer.
Dipropylene glycol dibenzoate (DPGDB) is compatible with PVC resin.
Dipropylene glycol dibenzoate (DPGDB) reduces the melting temperature and production time.



USES and APPLICATIONS of DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
Dipropylene glycol dibenzoate (DPGDB) is mainly used as plasticizer, for example, used in resilient floors, plastisol, adhesives, binder, coatings and coated materials,screen printing ink, sealants, filler and caulking materials, dyes, nail polish, skin protect product, photoresist, liquid crystal film, polymer of disposable hygiene products and food packaging, etc.


Dipropylene glycol dibenzoate (DPGDB) can be plasticized such as PVC, polyethylene/polypropylene, polyvinyl aceate£¬polystyrene, polyvinyl alcohol, polyvinyl butyral, polymethacrylate, polyisocyanate, polyurethane, phenolic resins, epoxy resins, polyether, ethylcellulose, cellulose butyrate, nitrocellulose, chloroethylene or ethylene-vinyl acetate copolymer, styrene-acrylate copolymer, ethylene-maleic anhydride copolymer, and so on.


In addition, Dipropylene glycol dibenzoate (DPGDB) is also as processing aid of natural or synthetic rubber, solubilizer and dispersant of pigments or toner, and as extractive distillation agent for the organics that their boiling points is proximity.
Coatings and inks: Dipropylene glycol dibenzoate (DPGDB) enhances flow, adhesion, and film formation in coatings and inks, resulting in a smooth and even finish.


Plastics: Dipropylene glycol dibenzoate (DPGDB) improves flexibility, durability, stability, and machinability as a plasticizer for plastics.
Adhesives: Dipropylene glycol dibenzoate (DPGDB) formulates adhesives with excellent bond strength, flexibility, and resistance to aging and plasticization.
Polymer processing: Dipropylene glycol dibenzoate (DPGDB) is used as a processing aid in polymer manufacturing, including extrusion, molding, and film production due to its stability and low volatility.


Personal care products: Dipropylene glycol dibenzoate (DPGDB) is added to creams, lotions, and hair care products to improve texture, stability, and moisturizing properties.
Industrial lubricants: Dipropylene glycol dibenzoate (DPGDB) acts as a lubricant additive, enhancing lubricity and reducing friction in various industrial applications.


Other applications: Dipropylene glycol dibenzoate (DPGDB) is utilized in detergents, solvents, printing inks, leather coatings, and more.
Dipropylene glycol dibenzoate (DPGDB)is used in PVC granule, non-filling rolling film, artificial leather, cable, board material, flaky material, pipe material, rubber bar, foam material, film, rubber and plastisol etc.


Dipropylene glycol dibenzoate (DPGDB) is mainly used as plasticizer, for example, used in resilient floors, plastisol, adhesives, binder, coatings and coated materials,screen printing ink, sealants, filler and caulking materials, dyes, nail polish, skin protect product, photoresist, liquid crystal film, polymer of disposable hygiene products and food packaging, etc., and it can be plasticized such as PVC, polyethylene/polypropylene, polyvinyl aceate£¬polystyrene, polyvinyl alcohol, polyvinyl butyral, polymethacrylate, polyisocyanate, polyurethane, phenolic resins, epoxy resins, polyether, ethylcellulose, cellulose butyrate, nitrocellulose, chloroethylene or ethylene-vinyl acetate copolymer, styrene-acrylate copolymer, ethylene-maleic anhydride copolymer, and so on.


In addition, Dipropylene glycol dibenzoate (DPGDB) is also as processing aid of natural or synthetic rubber, solubilizer and dispersant of pigments or toner, and as extractive distillation agent for the organics that their boiling points is proximity.
As a highly soluble benzoate plasticizer, Dipropylene glycol dibenzoate (DPGDB) is characterized by low toxicity and environmental protection, low gelling temperature, high plasticizing efficiency, large filling amount, good cold resistance and pollution resistance.


Dipropylene glycol dibenzoate (DPGDB) has been recognized and recommended by the European Union to replace the conventional chemicalbook o-benzene plasticizer and used as an environmental protection plasticizer.
Dipropylene glycol dibenzoate (DPGDB) finds extensive use in various industries.


Dipropylene glycol dibenzoate (DPGDB) is a high solvating Dibenzoate plasticizer.
Dipropylene glycol dibenzoate (DPGDB) is widely used in PVC synthetic plastics, water-based adhesive, polysulfide sealant, polyurethane sealant, artificial leather and synthetic rubber, and reflects its superior performance and plasticizing effect.


Dipropylene glycol dibenzoate (DPGDB) is a high solvating Dibenzoate plasticizer.
As a replacement for phthalate plasticizers, Dipropylene glycol dibenzoate (DPGDB) has been used for many years in a wide variety of applications, including adhesives, PS sealants, caulks, resilient flooring, PVC, artificial leather cloth PVC coated cloth, paints, links, etc.


Dipropylene glycol dibenzoate (DPGDB) is a high-quality compound with excellent stability, low volatility, and a high boiling point.
Dipropylene glycol dibenzoate (DPGDB) imparts desirable properties to formulations and is widely used in various applications.
Dipropylene glycol dibenzoate (DPGDB) is a high-quality compound used in a variety of applications.


As a replacement for phthalate plasticizers recommended by the European Chemical Agency(ECHA), Dipropylene glycol dibenzoate (DPGDB) has been used for many years in a wide variety of applications, including adhesives, PS sealants, caulks, resilient flooring, PVC, artificial leather cloth, PVC coated cloth, paints, inks, pesticides, etc.


Dipropylene glycol dibenzoate (DPGDB) is widely used in variety of applications, including caulk, adhesives, resilient flooring, PVC-coated fabrics and artificial-leather cloth.
In PVC, Dipropylene glycol dibenzoate (DPGDB) acts as a medium- viscosity high solvator that saves energy and improves process ability.


Vinyl applications using Dipropylene glycol dibenzoate (DPGDB) have excellent resistance to extraction from solvents and oils.
Dipropylene glycol dibenzoate (DPGDB) also works with vinyl to make it UV – light-degradation resistant and stain resistant.
As a replacement for phthalate plasticizers recommended by the European Chemical Agency(ECHA), Dipropylene glycol dibenzoate (DPGDB) has been used for many years in a wide variety of applications including adhesives, PS sealants, caulks, resilient flooring, PVC, artificial leather cloth, PVC coated cloth, paints, inks, pesticides, etc..


End Uses of Dipropylene glycol dibenzoate (DPGDB): Flexible Packaging, Film
Dipropylene glycol dibenzoate (DPGDB) is a high solvating Dibenzoate plasticizer.
As a replacement for phthalate plasticizers recommended, Dipropylene glycol dibenzoate (DPGDB) has been used for many years in a wide variety of applications, including adhesives, PS sealants, caulks, resilient flooring, PVC, artificial leather cloth, PVC-coated cloth, paints, inks, pesticides, etc.



PROPERTIES OF DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
Dipropylene glycol dibenzoate (DPGDB) is a transparent oily liquid of colorless to yellow.
Dipropylene glycol dibenzoate (DPGDB) soluble in aliphatic hydrocarbons and aromatic hydrocarbons, insoluble in water.



FUNCTIONS OF DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
*Plasticizer



KEY FEATURES AND PROPERTIES OF DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
*Excellent stability:
Dipropylene glycol dibenzoate (DPGDB) exhibits remarkable stability, making it ideal for applications that require long-term performance and resistance to degradation.

*Low volatility:
Dipropylene glycol dibenzoate (DPGDB) has a low vapor pressure, reducing the risk of evaporation during processing and extending its shelf life.

*High boiling point:
With a boiling point above 300°C, Dipropylene glycol dibenzoate (DPGDB) can withstand high temperatures, enhancing its suitability for various production processes.

*Imparts desirable properties to formulations:
Dipropylene glycol dibenzoate (DPGDB) acts as a versatile ingredient, providing improved viscosity, plasticization, lubrication, and film-forming properties to formulations.



PROPERTIES AND FEATURES OF DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
Dipropylene glycol dibenzoate (DPGDB) is a new Environment-friendly plasticizer.
Another name of Dipropylene glycol dibenzoate (DPGDB) is DPDB.
Dipropylene glycol dibenzoate (DPGDB) is haplotype and strong solvent based plasticizer, have light ill-smelling.

Dipropylene glycol dibenzoate (DPGDB) can be compatible with lots of polymers, very quickly dissolve vinyl resins, can reduce the melting temperature and reduce production time.
Dipropylene glycol dibenzoate (DPGDB) is resistant to mineral oil extract and has high flash point, no peculiar odor, no harm to touch, and has good compatibility with resins.



COMPOSITION AND PROPERTIES OF DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
Dipropylene glycol dibenzoate (DPGDB) is composed of dibenzoic acid esterified with propylene glycol.
Dipropylene glycol dibenzoate (DPGDB)'s chemical structure consists of two propylene glycol groups linked by a dibenzoate moiety.
With a purity of 75%, Dipropylene glycol dibenzoate (DPGDB) is suitable for a wide range of applications.



ADVANTAGES OF DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
1) Environmentally friendly plasticizers recommended by the European Chemical Agency (ECHA).
Dipropylene glycol dibenzoate (DPGDB) does not contain any phthalates and can be used as a main plasticizer.

2) High solvating.
Dipropylene glycol dibenzoate (DPGDB) has low fusing point which means faster processing speed. Very good foaming effect in PVC foaming process.

3) Dipropylene glycol dibenzoate (DPGDB) has a very good plasticizing effect which means more fillers can be added.
In PS sealants formulations, compared with traditional plasticizers, SW-DB342 added can be reduced by around 15%.

4) Compatible with compounds.
Dipropylene glycol dibenzoate (DPGDB) is containing SW-DB342 exhibit excellent stain and extraction resistance.
Dipropylene glycol dibenzoate (DPGDB) is soft under low temperature.
Dipropylene glycol dibenzoate (DPGDB) is impervious to light and heat.
Dipropylene glycol dibenzoate (DPGDB) has Low VOC content.



OVERVIEW OF DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
Dipropylene glycol dibenzoate (DPGDB) is a colorless or slightly yellowish liquid with a high boiling point.
Dipropylene glycol dibenzoate (DPGDB) is extensively used in various industries for its remarkable stability, low volatility, and ability to impart desirable properties to formulations.
Dipropylene glycol dibenzoate (DPGDB) is a valuable ingredient that enhances the performance and quality of coatings, plastics, adhesives, polymer processing, personal care products, industrial lubricants, and more.



PHYSICAL and CHEMICAL PROPERTIES of DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
Appearance: Transparent oily liquid of colorless to yellow
Assay of ester(HPLC),: %≥98.0
Acid value, KOHmg/g: ≤0.3
Flash point, ℃: ≥206
Specific gravity: 1.01-1.12
Molecular Formula: C20H22O5
Molecular weight: 342.39
CAS No.: 27138-31-4
EC No.: 248-258-5
Physical state: viscous liquid
Color: colorless
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: 232 °C at 7 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 192 °C - closed cup - ASTM D 93
Autoignition temperature: > 400 °C at 1013 hPa
Decomposition temperature: > 270 °C
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: ca.0,00869 g/l at 20 °C - slightly soluble
Partition coefficient: n-octanol/water:
log Pow: 3,9 at 20 °C
Vapor pressure: No data available
Density: 1,12 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not explosive
Oxidizing properties: No data available
Other safety information:
Surface tension: 59 mN/m at 20 °C
Appearance : transparent oily liquid , free of particulate impurities.
Assay (Benzoic esters):99.0% min.
Acidity (calculated as Benzoic Acid):0.1% max.
Color (APHA):80 max.

Moisture:0.1% max.
Hydroxyl No.:13 max.
Molecular Weight: 342
Boiling Point(5mmHg,ºC):230
Freezing Point(ºC): -30
Pour Point(ºC): -19
Flash Point(TCC,ºC): >150
Refractive Index(25ºC): 1.5282
Specific Gravity(25ºC): 1.12-1.13
Viscosity(Brookfield,25ºC): 120 cps
VOC Content: <3%
Odor: Mild ester-like
Boiling point: 232 °C5 mm Hg(lit.)
Density: 1.12 g/mL at 25 °C(lit.)
vapor pressure: 0 Pa at 25℃
refractive index: n20/D 1.528(lit.)
Flash point: >230 °F
storage temp.: Sealed in dry,Room Temperature

Water Solubility: 8.69mg/L at 20℃
Stability: Stable.
Incompatible with strong oxidizing agents.
InChIKey: IZYUWBATGXUSIK-UHFFFAOYSA-N
LogP: 3.9 at 20℃
CAS DataBase Reference: 27138-31-4(CAS DataBase Reference)
EPA Substance Registry System: Dipropylene glycol dibenzoate (27138-31-4)
Molecular Formula: C 20 H 22 O 5
Molecular Weight: 342.3857
InChI: InChI=1/C20H22O5/c1-3-17(24-19(21)15-11-7-5-8-12-15)23-18(4-2)25-20(22)16-13- 9-6-10-14-16/h5-14,17-18H,3-4H2,1-2H3
CAS registration number: 27138-31-4
EINECS: 248-258-5
Intensity: 1.144g/ cm3
Boiling point: 464.198°C at 760 mmHg
Refractive index: 1,542
Flash point: 202.303°C



FIRST AID MEASURES of DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
-Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
-Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing,
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.



HANDLING and STORAGE of DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



DIPROPYLENE GLYCOL DIBENZOATE (DPGDB)
DESCRIPTION:
Dipropylene glycol dibenzoate(DPGDB) acts as a plasticizer.
Dipropylene glycol dibenzoate(DPGDB) is compatible with PVC resin.
Dipropylene glycol dibenzoate(DPGDB) reduces the melting temperature and production time.
Dipropylene glycol dibenzoate(DPGDB) is used in PVC granule, non-filling rolling film, artificial leather, cable, board material, flaky material, pipe material, rubber bar, foam material, film, rubber and plastisol etc.

CAS Number: 27138-31-4
EC Number: 248-258-5
Molecular Weight: 342.39
Linear Formula:
(C6H5CO2C3H6)2O


SYNONYMS OF DIPROPYLENE GLYCOL DIBENZOATE(DPGDB):
DPGDB; Oxydipropyl Dibenzoate; Benzoic Acid N-Dipropylene Glycol Diester; Dipropanediol Dibenzoate;dpgdb; oxybis-propanodibenzoate;oxydipropyl dibenzoate; oxydipropylenedibenzoate ;benzoflex 284 ; dimethylolurea, tech;k-flex dp; dpg dibenzoate;dipropylenglycoldibenzoate; dipropanediol dibenzoate




Dipropylene glycol dibenzoate (DPGDB) is halotype dipropylene glycol dibenzoate.
Dipropylene glycol dibenzoate(DPGDB) Acts as a plasticizer.

Dipropylene glycol dibenzoate(DPGDB) is compatible with lots of polymer and dissolves vinyl resins.
Dipropylene glycol dibenzoate(DPGDB) reduces the melting temperature and production time.

Dipropylene glycol dibenzoate(DPGDB) is resistant to mineral oil extract and has high flash point.
Dipropylene glycol dibenzoate (DPGDB) is suitable for vinyl-acetate adhesive.

Dipropylene glycol dibenzoate is haplotype and Strong solvent based plasticizer.have light ill-smelling.
Dipropylene glycol dibenzoate(DPGDB) can be compatible with lots of polymer,very faster dissolve vinyl resins. can reduce the melting temperature and reduce production time.

This product is resistant to mineral oil extract and have high flash point no peculiar odour. no harm of touch, have a good compatibility with resins.

Dipropylene glycol dibenzoate(DPGDB) can retain the foam structure of tiny when produce opening vinyl foam.

Foam products very soft, pore uniformity similar to soft leather.
Dipropylene glycol dibenzoate(DPGDB) be made into vinyl flooring can not be infiltration and pollution by asphalt.


USES OF DIPROPYLENE GLYCOL DIBENZOATE(DPGDB):
Dipropylene glycol dibenzoate(DPGDB) is used in Adhesives & Sealants,
Dipropylene glycol dibenzoate(DPGDB) is used in Agricultural Chemicals,
Dipropylene glycol dibenzoate(DPGDB) is used in Automotive Sealants,

Dipropylene glycol dibenzoate(DPGDB) is used in Crop Protection,
Dipropylene glycol dibenzoate(DPGDB) is used in Epoxy Coatings,
Dipropylene glycol dibenzoate(DPGDB) is used in Inks & Digital Inks,

Dipropylene glycol dibenzoate(DPGDB) is used in Nail Polish Remover,
Dipropylene glycol dibenzoate(DPGDB) is used in Plastic, Resin & Rubber,
Dipropylene glycol dibenzoate(DPGDB) is used in Textile Auxiliaries,

Dipropylene glycol dibenzoate(DPGDB) is used in Benzoates,
Dipropylene glycol dibenzoate(DPGDB) is used in Coatings,
Dipropylene glycol dibenzoate(DPGDB) is used in Copolymers,

Dipropylene glycol dibenzoate(DPGDB) is used in Leather,
Dipropylene glycol dibenzoate(DPGDB) is used in Paints,
Dipropylene glycol dibenzoate(DPGDB) is used in Pesticides,
Dipropylene glycol dibenzoate(DPGDB) is used in Plasticizers



APPLICATIONS OF DIPROPYLENE GLYCOL DIBENZOATE(DPGDB):
Dipropylene glycol dibenzoate(DPGDB) is used in may be used as a diluent for the preparation of polysulfone membranes by heat induced phase separation.
Dipropylene glycol dibenzoate(DPGDB) is used in finds potential applications in water treatment and food processing.
Dipropylene glycol dibenzoate(DPGDB) is used in may also be used as a plasticizer with poly(vinyl) chloride (PVC) for the fabrication of diamond coated PVC

Dipropylene glycol dibenzoate(DPGDB) is used in is a high solvating Dibenzoate plasticizer.
As a replacement for phthalate plasticizers recommended by the European Chemical Agency (ECHA), it has been used for many years in a wide variety of applications, including adhesives, PS sealants, caulks, resilient flooring, PVC, artificial leather cloth PVC coated cloth, paints, links, etc.


Dipropylene glycol dibenzoate is a new Environment-friendly plasticizer in China.
Another name is DPGDB or DPDB.
Dipropylene glycol dibenzoate(DPGDB) is used in is haplotype and strong solvent based plasticizer, have light ill-smelling.

Dipropylene glycol dibenzoate(DPGDB) is used in can be compatible with lots of polymers, very faster dissolve vinyl resins, can reduce the melting temperature and reduce production time.
Dipropylene glycol dibenzoate(DPGDB) is used in is resistant to mineral oil extract and have high flash point no peculiar odor, no harm of touch, have a good compatibility with resins.


ADVANTAGES OF DIPROPYLENE GLYCOL DIBENZOATE(DPGDB):
Environmentally friendly plasticizers recommended by the European Chemical Agency (ECHA).
Dipropylene glycol dibenzoate(DPGDB) Does not contain any phthalates and can be used as a main plasticizer.

Dipropylene glycol dibenzoate(DPGDB) is High solvating. Low fusing point which means faster processing speed.
Dipropylene glycol dibenzoate(DPGDB) has Very good foaming effect in PVC foaming process.

Dipropylene glycol dibenzoate(DPGDB) has Very good plasticizing effect which means more fillers can be added.
In PS sealants formulations, compared with traditional plasticizers, SW-DB342 added can be reduced by around 15%.

Dipropylene glycol dibenzoate(DPGDB) is Compatible with compounds.
Products containing SW-DB342 exhibit excellent stain and extraction resistance.
Dipropylene glycol dibenzoate(DPGDB) is Soft under low temperature.
Dipropylene glycol dibenzoate(DPGDB) is Impervious to light and heat.



CHEMICAL AND PHYSICAL PROPERTIES OF DIPROPYLENE GLYCOL DIBENZOATE(DPGDB):
grade
technical grade
Quality Level
100
Assay
75%
refractive index
n20/D 1.528 (lit.)
bp
232 °C/5 mmHg (lit.)
density
1.12 g/mL at 25 °C (lit.)
SMILES string
O=C(OCCCOCCCOC(=O)c1ccccc1)c2ccccc2
InChI
1S/C20H22O5/c21-19(17-9-3-1-4-10-17)24-15-7-13-23-14-8-16-25-20(22)18-11-5-2-6-12-18/h1-6,9-12H,7-8,13-16H2
InChI key
BYQDGAVOOHIJQS-UHFFFAOYSA-N
Categories
Polymer science compounds,Polymerization initiators
Assay
97%
Appearance (Form)
Viscous liquid
Appearance (Colour)
Colourless
Density
1.12 g/mL at 25 °C (lit.)
Appearance, Transparent oily liquid, free of particulate impurities
Acidity ( Calculated as Benzoic Acid ), 0.1% max
Color ( APHA ), 100 max
Assay ( Benzoic esters ), 99.0% min
Moisture, 0.1% max
Density:
1.12 g/mL at 25 °C(lit.)
Boiling Point:
232 °C5 mm Hg(lit.)
Flash Point:
>230 ºF
Refractive index:
n20D 1.528(lit.)
Purity(GC),% ≥98
Acid value(mgKOH/g) ≤0.1
Flash point(℃) ≥200
Water(KF) ≤0.1
Specific weight(25℃,g/cm³) ≤1.12
Color (Pt-Co Hz) ≤80
Appearance:transparent oily liquid,free of particulate impurities.
Assay(Benzoic esters):99.0% min.
Acidity(calculated as Benzoic Acid):0.1% max.
Color(APHA):80 max.
Moisture:0.1% max.
Hydroxyl No.:13 max.
Typical PropertiesSolubility
In water:< 0.01%
Water in:<0.25%
Molecular Weight 342
Boiling Point(5mmHg,℃) 230
Freezing Point(℃) -30
Pour Point(℃) -19
Flash Point(TCC,℃) >150
Refractive Index(25℃) 1.5282
Specific Gravity(25℃) 1.120-1.125
Viscosity(Brookfield,25℃) 120 cps
VOC Content: <3%
Odor Mild ester-like


SAFETY INFORMATION ABOUT DIPROPYLENE GLYCOL DIBENZOATE (DPGDB):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product



DIPROPYLENE GLYCOL DIBENZOATE (NON-PHTHALATE PLASTICIZER)
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a polar, high-solvating plasticizer.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer for cast urethane applications.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is compatible with a wide range of polar polymers and rubbers.

CAS Number: 27138-31-4
Molecular Formula: C20H22O5
Molecular Weight: 342.39
EINECS Number: 248-258-5

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is useful in applications such as latex caulks, adhesive, and sealants, coatings and vinyl plastisols.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is based on Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) and offers lower cure interference and reduced loading rate in polyurethane systems.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer for use with cast urethanes.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) offers minimum cure interference and is compatible with both ethers and esters.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer used in various industries, primarily in the production of polymers and plastics.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) serves as a replacement for traditional phthalate plasticizers, which have raised concerns due to potential health and environmental risks.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)is also claimed to have some humectant and moisturizing properties without a greasy after-feel.
But its real superpower is being an outstanding solvent for hard to solubilize sunscreen agents (that is most of the chemical sunscreen filters) making it an excellent emollient choice in high SPF products.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is compatible with a wide range of polar polymers and rubbers.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a plasticizer comprising xylylene glycol di-2-ethylhexanoate.
The plasticizer can Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) and a second plasticizer.
Also disclosed is a plastisol comprising a PVC resin dispersed in the liquid phase and a plasticizer Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) and a second plasticizer.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is useful in applications such as latex caulks, adhesive, and sealants, coatings and vinyl plastisols.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a widely used plasticizer that has ether linkages linked with two benzoate groups.
Additionally disclosed, an article can comprise the fused plastisol.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s are high solvating plasticisers for PVC, available as either monobenzoates (benzoates) or dibenzoates.
They are mainly used in PVC plastisol applications including flooring and film, but also in adhesives and sealants.
The SG is a "special grade" with a maximum hydroxyl number specification designed for use in urethane prepolymers.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s are produced by esterification of benzoic acid with high molecular weight alcohols like isononanol or isodecanol.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s are made by the reaction of diols like diethylene glyol, triethylene glycol or dipropylene glycol with benzoic acid.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s are in general fast fusing plasticisers offering complemetary performances to general purpose plasticisers.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s also work as low VOC and low viscosity agents for PVC plastisols.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is useful in applications such as latex caulks, adhesive, and sealants, coatings and vinyl plastisols.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer), which is one of the oldest members of the plasticizer family and one of the most versatile polar plasticizers is still commercially available in our stocks.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) by Chemceed is Dipropylene Glycol Dibenzoate (non-phthalate plasticizer).
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a polar, high-solvating plasticizer.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is compatible with a wide range of polar polymers and rubbers.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used in applications such as latex caulks, adhesives and sealants.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is compatible with a wide range of polar polymers and rubbers and is often blended with other plasticizers such as diethylene glycol dibenzoate.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is non-phthalate, plasticizer.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) offers good flexibility, viscosity response, and adhesion (even to challenging substrates), extended open times, reduced set times, improved wet tack, and enhanced weatherability.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is an environmentally friendly plasticizers recommended by the European Chemical Agency.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) does not contain any phthalates and can be used as primary plasticizers.

Data from more than 30 years applications and tests show Dibenzoate esters are low in toxicity, non-mutagenic, non-carcinogenic and easy to degrade.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) has high solvating and lower fusing point which means faster processing speed.
Very good foaming effect in PVC foaming process.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is compatible with EVA emulsions, polysulfphur rubbers and PVC.
A good combination of cost and performance in waterborne adhesives industry, polysulfphur sealants industry and PVC resilient flooring industry.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) achieves excellent performance and compatibility in waterborne adhesives, latex caulks, and reactive sealants, including acrylic, VAE, PVAc, STPE, and STPU type chemistries.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be used in food contact- and pressure sensitive adhesives and plastisols.
In adhesives applications, such as putty and water-based latex adhesives, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is an effective, low-VOC choice.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) also offers easier handling due to its extremely low freeze point.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) has excellent compatibility with a wide range of polar polymers and rubbers and is often blended with other plasticizers.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is added to polymers and plastics to improve their flexibility, durability, and other mechanical properties.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) helps reduce brittleness and enhances the processability of the materials during manufacturing.

The term "non-phthalate" indicates that DPGD does not contain phthalates, a group of chemicals that have been subject to regulatory scrutiny due to their potential adverse effects on human health, especially in certain applications like toys and medical devices.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is known for its low volatility, which means it has reduced tendencies to evaporate into the air.
This characteristic can be advantageous in applications where low volatility is desired.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is commonly used in the production of various plastic products, including films, sheets, cables, and molded items.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) finds applications in industries such as packaging, construction, automotive, and more.
Non-phthalate plasticizers like Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) are often chosen to address concerns related to the potential health and environmental impacts associated with certain phthalate compounds.

Phthalates have been linked to endocrine disruption and other health issues.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a high solvator and delivers value to many applications, but it is particularly recommended for coatings, such as nitrocellulosic and acrylic lacquers, and vinyl applications, such as plastisol printing.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is one of the most versatile polar, high solvating plasticizers.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is compatible with a wide range of polar polymers and rubbers, including TPU.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is haplotype and Strong solvent based plasticizer.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be compatible with lots of polymer,very fast dissolve vinyl resins.
Can reduce the melting temperature and reduce production time.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is resistant to mineral oil extract and has a high flash point with no peculiar odour.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is one of the most versatile polar, high solvating plasticizers.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is an excellent choice for high solvating plasticizer applications.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a high solvating plasticizer that has been used for many years in a wide variety of polymer systems and applications.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is diverse uses include resilient flooring, adhesives, artificial leather cloth and caulk.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer specifically designed for 2K polyurethane systems where it is very compatible and efficient.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a diester formed by the esterification of dipropylene glycol with benzoic acid.

The chemical structure typically involves two benzoyl (benzoate) groups linked to the Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) backbone.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) exhibits good compatibility with a variety of resin systems, including polyvinyl chloride (PVC), polyethylene, and others.
This compatibility makes Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) a versatile choice for use in different polymer matrices.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) often demonstrates good thermal stability, allowing it to withstand a range of temperatures encountered during processing and use of plastic materials.
One of the primary functions of Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is to enhance the flexibility of plastics.
This is particularly important in applications where flexibility is a crucial property, such as in the production of flexible films, cables, and certain molded products.

Non-phthalate plasticizers like Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) are chosen by manufacturers seeking to comply with regulatory standards that restrict or discourage the use of certain phthalate plasticizers in consumer products.
Regulations may vary by region, and it's essential for manufacturers to stay informed about the specific requirements applicable to their products.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is an oily liquid that makes your skin nice and smooth (aka emollient).

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is also claimed to have some humectant and moisturizing properties without a greasy after-feel.
But Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is real superpower is being an outstanding solvent for hard to solubilize sunscreen agents (that is most of the chemical sunscreen filters) making it an excellent emollient choice in high SPF products.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can retain the foam structure of tiny when producing opening vinyl foam. Foam products are very soft, pore uniformly similar to soft leather.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is made into vinyl flooring and can not be infiltrated and polluted by asphalt.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer specifically designed for 2K polyurethane systems where it is very compatible and efficient.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer for cast urethane applications.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is based on Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) and offers lower cure interference and reduced loading rate in polyurethane systems.

Boiling point: 232 °C5 mm Hg(lit.)
Density: 1.12 g/mL at 25 °C(lit.)
vapor pressure: 0Pa at 25℃
refractive index: n20/D 1.528(lit.)
Flash point: >230 °F
storage temp.: Sealed in dry,Room Temperature
Water Solubility: 8.69mg/L at 20℃
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: IZYUWBATGXUSIK-UHFFFAOYSA-N
LogP: 3.9 at 20℃

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is often considered to be more biodegradable compared to some traditional phthalate plasticizers.
Biodegradability can be an important factor in assessing the environmental impact of plastic materials over their lifecycle.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) typically exhibits good hydrolytic stability, meaning it resists degradation when exposed to water.

This property is advantageous in applications where the plastic material may come into contact with moisture.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can contribute to the UV resistance of plastic materials.
This is particularly relevant in outdoor applications where exposure to sunlight can lead to degradation of polymers.

Manufacturers may choose Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) for its ability to be tailored to specific formulation requirements.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be part of a formulation strategy to achieve desired properties in the final plastic product.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) has gained acceptance in various markets globally as a viable alternative to phthalate plasticizers.

This acceptance is influenced by regulatory trends, consumer preferences, and the overall push towards safer and more sustainable materials.
Ongoing research and development efforts in the field of plasticizers aim to improve the performance, environmental impact, and safety profile of these additives.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer), being a part of this landscape, may see further refinements and innovations in the future.

Collaboration between industry stakeholders, including manufacturers, researchers, and regulatory bodies, plays a crucial role in shaping the direction of plasticizer development.
The exchange of knowledge and expertise contributes to the continuous improvement of plasticizer technologies.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer, there are other alternatives in the market, each with its own set of properties and advantages.

These alternatives include dioctyl terephthalate (DOTP), diisononyl phthalate (DINP), and various bio-based plasticizers.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a blend of Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) and diethylene glycol dibenzoate specifically designed for vinyl applications with economy as a focus.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is similar in composition to K-FLEX® 850S (diethylene glycol dibenzoate rich).

As a high solvator for vinyl it can be formulated alone or in blends for plastisols as well as melt compounded vinyl.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) works as a viscosity control aid in wax based-hair removal products.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a Polyoxypropylene glycol diester of benzoic acid.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) uses and applications include: Plasticizer for cellulosics, PVC, plastisols, PS, PVB, PVAc adhesives, VCA, castable PU; latex and lacquer coating applications; film-former, surfactant wetting agent in PVAc homopolymer emulsion adhesives; emollient in cosmetics; plasticizer for PVAc coatings for food-contact paperpaperboard; plasticizer for polymers in paperpaperboard in contact with dry food; in food packaging adhesives.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a widely used plasticizer that has ether linkages linked with two benzoate groups.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is recommended for cast urethane applications that require minimum cure interference and maximum compatibility.
Offers excellent inert filler acceptance, contributes improved tear strength, better rebound and reduces swell with certain solvents.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is adaptable to both metering and hand batch urethane mix systems.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be used as a plasticizer for PVC, PVC and polyurethane resins.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) has strong solvent action, good compatibility, low volatility, good durability, oil resistance and pollution resistance.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is often used for high filling PVC floor materials and extrusion plastics.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is designed to have low migration rates from plastics to adjacent materials.
This property is significant in applications where the potential for chemical migration can impact the safety and quality of the end product, such as in food packaging.

The use of non-phthalate plasticizers, including DPGD, reflects broader industry trends toward more sustainable and environmentally friendly practices.
Manufacturers and consumers alike have shown increasing interest in products that minimize potential health and environmental risks associated with certain chemical additives.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can improve processability, reduce processing temperature and shorten processing cycle.

When used in non filling films, sheets and pipes, the products are transparent and glossy.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer specifically designed for 2K polyurethane systems where it is very compatible and efficient.
Is a non-phthalate plasticizer that offers excellent inert filler acceptance, contributes improved tear strength, better rebound and reduces swelling with certain solvents.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s are an environmentally friendly option for formulators looking for an alternative to commodity and specialty phthalate esters.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a non-phthalate plasticizer and uses benzoic acid as a key raw material.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is therefore a more environmentally-friendly product versus traditional commodity phthalates that have been linked to human health issues.

While Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is not a green plasticizer, it is derived from benzoic acid, which in its salt form, is used as a food preservative in jams, soft drinks, pickled foods and spreads.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) continually looks for opportunities to expand its product line and part of its product line may extend into bio-based plasticizers.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a new Environment-friendly plasticizer in China.

Another name is DPGDB or DPDB.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is haplotype and strong solvent based plasticizer, and has light ill-smelling.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be compatible with lots of polymers, very fast dissolve vinyl resins, can reduce the melting temperature and reduce production time.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is resistant to mineral oil extract and has a high flash point, no peculiar odor, no harm of touch, and has a good compatibility with resins.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is compatible with PVC resin.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) reduces the melting temperature and production time.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used in PVC granule, non-filling rolling film, artificial leather, cable, board material, flaky material, pipe material, rubber bar, foam material, film, rubber and plastisol etc.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a high solvating Dibenzoate plasticizer.
Its main component is Dipropylene Glycol Dibenzoate (non-phthalate plasticizer).

As a replacement for phthalate plasticizers recommended by the European Chemical Agency(ECHA),it has been used for many years in a wide variety of applications,including adhesives,PS sealants,caulks, resilient flooring,PVC,artificial leather cloth,PVC coated cloth,paints,inks,pesticides, etc.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be used as a diluent for the preparation of polysulfone membranes by heat induced phase separation.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) finds potential applications in water treatment and food processing.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may also be used as a plasticizer with poly(vinyl) chloride (PVC) for the fabrication of diamond coated PVC.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s are used in a number of applications, including adhesives, sealants, caulk, coatings and inks, plastisol and various flexible PVC uses.
Plasticizers for polyurethanes are especially designed to have low moisture and a low hydroxyl number to enhance the consistency of the final polyurethane piece or coating.

The end result yields higher quality and more reproducible final products.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) prides itself in its strong participation in urethane plasticizer applications as they are highly demanding and precise in their tolerance requirements.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) has the solvating power that affords ample formulating latitude for optimized PVC formulations.

Typical plastisol applications include calendering, flooring, or automotive plastisol sealants.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s are high performance plasticizers.
They are polar and monomeric in nature.

In most cases, they provide superior performance compared to other plasticizers as it relates to polymer compatibility, efficiency and desired softness.
Overall permanence characteristics which account for these Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) to remain within the polymer matrix are also quite desirable.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s are low-to-medium-viscosity fluid esters compatible with a wide range of polymeric systems.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be analyzed by this reverse phase (RP) HPLC method with simple conditions.
The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid.
For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s columns available for fast UPLC applications.
This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) also suitable for pharmacokinetics.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a transparent oily liquid of colorless to yellow.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) soluble in aliphatic hydrocarbons and aromatic hydrocarbons, insoluble in water.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer), with the CAS registry number 27138-31-4, is also known as Dipropylene Glycol Dibenzoate (non-phthalate plasticizer); 2-[1- (Benzoyloxy)propan-2-yloxy]propyl benzoate.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) belongs to the product categories of Plasticizers;Polymer Additives;Polymer Science.
This chemical's molecular formula is C20H22O5 and molecular weight is 342.39.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is EINECS number is 248-258-5.
What's more,Its systematic name is Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) .
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is stable,combustible,incompatible with strong oxidizing agents.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is a Polyoxypropylene glycol diester of benzoic acid Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) uses and applications include: Plasticizer for cellulosics, PVC, plastisols, PS, PVB, PVAc adhesives, VCA, castable PU; latex and lacquer coating applications; filmformer, surfactant wetting agent in PVAc homopolymer emulsion adhesives; emollient in cosmetics; plasticizer for PVAc coatings for foodcontact paper paperboard; plasticizer for polymers in paper paperboard in contact with dry food; in food packaging adhesives.

Uses:
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be used as a diluent for the preparation of polysulfone membranes by heat induced phase separation.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) finds potential applications in water treatment and food processing.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may also be used as a plasticizer with poly(vinyl) chloride (PVC) for the fabrication of diamond coated PVC.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used in the following products: polymers, coating products, inks and toners, cosmetics and personal care products, adhesives and sealants, biocides (e.g. disinfectants, pest control products) and plant protection products.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is often used as a plasticizer in the production of polyvinyl chloride (PVC) products, including flexible films, sheets, and cables.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be incorporated into molded plastic items to improve their flexibility and overall mechanical properties.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be used in the formulation of construction materials such as PVC pipes, fittings, and profiles, where flexibility and durability are essential.
In the packaging industry, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be found in flexible packaging materials like films and sheets, providing the necessary flexibility for packaging applications.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used in automotive interiors, such as in the production of flexible components like instrument panels, door panels, and upholstery, where it enhances flexibility and resilience.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be used as a plasticizer in the production of wire and cable coatings, improving the flexibility and durability of the materials.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may find application in the production of various consumer goods, including toys and household items, where its use as a non-phthalate plasticizer aligns with regulatory requirements.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be used in certain applications where a non-phthalate plasticizer is preferred, such as in the production of medical tubing and devices.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be utilized in the textile industry, particularly in the production of coated fabrics and synthetic leather, where it contributes to flexibility and durability.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be incorporated into formulations for adhesives and sealants to improve flexibility and performance.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be employed in various industrial applications where the need for a non-phthalate plasticizer is identified, and flexibility and durability are critical considerations.
Other release to the environment of Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

Release to the environment of Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can occur from industrial use: in the production of articles, formulation of mixtures and in processing aids at industrial sites.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)s are mainly used in PVA (polyvinyl acetate) emulsion adhesives, caulks, sealants, coatings.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used as a plasticizer for polyvinyl chloride, polyvinyl acetate, polyurethane and other resins.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used as a plasticizer for elastic flooring, plastisols, adhesives, adhesives, coatings and coating materials, screen printing inks, sealants, fillers and caulking materials, dyes, nail polish, skin care products , Photoresist, liquid crystal film, disposable sanitary products and polymer materials for food packaging, etc.
Other release to the environment of Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is mainly used as plasticizer, for example, used in resilient floors, plastisol, adhesives, binder, coatings and coated materials,screen printing ink, sealants, filler and caulking materials, dyes, nail polish, skin protect product, photoresist, liquid crystal film, polymer of disposable hygiene products and food packaging, etc., and it can be plasticized such as PVC, polyethylene/polypropylene, polyvinyl aceate£¬polystyrene, polyvinyl alcohol, polyvinyl butyral, polymethacrylate, polyisocyanate, polyurethane, phenolic resins, epoxy resins, polyether, ethylcellulose, cellulose butyrate, nitrocellulose, chloroethylene or ethylene-vinyl acetate copolymer, styreneacrylate copolymer, ethylene-maleic anhydride copolymer, and so on. In addition, this product is also as processing aid of natural or synthetic rubber, solubilizer and dispersant of pigments or toner, and as extractive distillation agent for the organics that their boiling points is proximity.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be incorporated into the production of agricultural films used for greenhouse coverings or mulching.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is flexibility and durability can be beneficial in these applications.
In the construction industry, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may find use in waterproofing membranes, contributing to their flexibility and resistance to environmental elements.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) might be used in the production of flexible components in footwear, such as shoe soles and straps.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be utilized in the production of foam and sponge materials where flexibility is crucial, such as in packaging or cushioning applications.
Within the automotive industry, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be used in the production of interior trim components, including dashboards and door panels, to enhance flexibility and durability.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be employed in formulations of thermoplastic elastomers, contributing to their elastic properties.
In the manufacturing of gaskets and seals, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be added to improve flexibility and resistance to deformation.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) might be used in the production of medical tubing, where flexibility, biocompatibility, and regulatory compliance are critical.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can contribute to the flexibility and resilience of flooring materials, including resilient or cushioned flooring.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be considered in the formulation of biodegradable plastics, contributing to their overall flexibility while addressing environmental concerns.
In the production of disposable gloves, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) might be used to enhance flexibility and comfort.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can find applications in laminates and coated fabrics, providing flexibility to these materials for various purposes.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used for a wide variety of applications, including latex adhesives, caulks, PS sealants, polyvinyl chloride, resilient flooring, paints and coatings (as coalescents).
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) has been widely used in adhesive industry.

Other release to the environment of Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used in the following products: cosmetics and personal care products, adhesives and sealants, coating products and lubricants and greases.

Release to the environment of Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can occur from industrial use: formulation of mixtures and formulation in materials.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used in the following products: coating products, inks and toners, adhesives and sealants, lubricants and greases and cosmetics and personal care products.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be incorporated into the formulation of printing inks, contributing to their flexibility and improving adhesion properties when applied to different surfaces.

In the production of vinyl flooring materials, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be used to enhance the flexibility and durability of the flooring products.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) might find application in certain coatings and paints, especially those requiring flexibility and resistance to environmental factors.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is commonly used in the extrusion process for producing films and sheets, providing the necessary plasticity for shaping and forming these materials.

In the construction industry, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be included in sealant and caulk formulations to improve their flexibility and adhesion properties.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be utilized in the production of flexible hoses and tubing, contributing to the materials' ability to bend and conform without cracking.
Within the textile industry, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be used as a softening agent or auxiliary in textile processing to impart flexibility to fabrics.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may find use in electrical insulation applications where flexibility and resistance to temperature variations are crucial.
In the manufacturing of synthetic leather or faux leather, Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can be employed to enhance the material's suppleness and feel.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be incorporated into formulations for industrial belts, providing the necessary flexibility for conveying systems.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used for the manufacture of: machinery and vehicles and chemicals.
Release to the environment of Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) can occur from industrial use: in the production of articles, in processing aids at industrial sites and of substances in closed systems with minimal release.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is used as a solvator for PVC, plasticizer in elastomers, in vinyl flooring, adhesives, latex caulks and sealants, color concentrates for PVC, and castable polyurethanes; [EPA ChAMP: Submissions - Robust Summaries] Used to formulate adhesives, sealants, lubricants, plasticizers, coatings, and inks, to make fine and large scale chemicals, and as a plasticizer for PVC and carrier for agrochemicals; Permitted for use as an inert ingredient in non-food pesticide products.

Safety Profile:
Inhalation of vapor or mist may cause respiratory irritation.
Adequate ventilation should be maintained in areas where Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is handled.
Prolonged or repeated skin contact may lead to mild irritation.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer)'s advisable to use appropriate personal protective equipment, such as gloves, when working with Dipropylene Glycol Dibenzoate (non-phthalate plasticizer).
Direct contact with the eyes may cause irritation.
Safety goggles or a face shield should be used to protect the eyes.

Ingestion of Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is not expected to be a common route of exposure.
However, it may cause gastrointestinal irritation if swallowed.
Ingestion should be avoided, and good hygiene practices should be followed.

Environmental Impact:
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is often chosen for its relatively low environmental impact compared to certain other plasticizers, spillage or improper disposal can still have environmental consequences.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is important to follow appropriate waste disposal practices.

Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is not highly flammable, but like many organic compounds, it can burn.
Firefighters should use standard firefighting procedures if a fire involving Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) occurs.

Occupational exposure limits (OELs) for Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) may be established by regulatory authorities in different regions.
Dipropylene Glycol Dibenzoate (non-phthalate plasticizer) is essential for employers and workers to be aware of and adhere to such limits to prevent excessive exposure.

Synonyms:
27138-31-4
94-03-1
Oxydipropyl dibenzoate
1,1'-Oxybis-2-propanol dibenzoate
1,1'-Dimethyl-2,2'-oxydiethyl dibenzoate
9QQI0RSO3H
2-Propanol, 1,1'-oxybis-, dibenzoate
Oxybis(propane-1,2-diyl) dibenzoate
DTXCID507921
DTXSID6027921
CAS-27138-31-4
EINECS 202-296-9
UNII-9QQI0RSO3H
1,1'-OXYBIS(2-PROPANOL) DIBENZOATE
1-(2-benzoyloxypropoxy)propan-2-yl benzoate
SCHEMBL1255193
CHEMBL1877406
DTXSID401043495
Tox21_202280
Tox21_300147
MFCD00046063
NCGC00164208-01
NCGC00247908-01
NCGC00254168-01
NCGC00259829-01
1,1'-oxybis(propane-2,1-diyl) dibenzoate
2-Propanol,1,1'-oxybis-,dibenzoate(9ci)
FT-0698140
2-PROPANOL, 1,1'-OXYDI-, DIBENZOATE
Q27272899
DI(1,2-PROPYLENE GLYCOL) DIBENZOATE, TAIL TO TAIL-
DIPROPYLENE GLYCOL DIMETHYL ETHER

Dipropylene glycol dimethyl ether (Dipropylene Glycol Dimethyl Ether) is a chemical compound with the molecular formula C8H18O3.
Dipropylene Glycol Dimethyl Ether belongs to the family of glycol ethers and is a clear, colorless liquid with a mild, ether-like odor.
Dipropylene Glycol Dimethyl Ether is composed of two propylene glycol units and one dimethyl ether unit.

CAS number: 111109-77-4



APPLICATIONS


Dipropylene Glycol Dimethyl Ether is widely used as a solvent in the formulation of coatings and paints, enhancing solubility and promoting smooth application.
Dipropylene Glycol Dimethyl Ether serves as a solvent in printing inks, facilitating the dissolution of pigments and resins for vibrant and high-quality prints.

Dipropylene Glycol Dimethyl Ether finds application in adhesives and sealants, aiding in the dispersion and compatibility of adhesive components.
Dipropylene Glycol Dimethyl Ether is utilized in industrial cleaning agents, effectively dissolving oils, greases, and contaminants for thorough cleaning.
Dipropylene Glycol Dimethyl Ether acts as a solvent and reaction medium in various industrial processes, including extraction and chemical synthesis.

In the electronics industry, it serves as a solvent for cleaning electronic components and as a carrier solvent for electronic formulations.
Dipropylene Glycol Dimethyl Ether is used as a solvent in the production of lithium-ion battery electrolytes, contributing to battery performance and stability.

Dipropylene Glycol Dimethyl Ether can be found in personal care products, such as cosmetics and skin care formulations, aiding in solubilization and formulation stability.
Dipropylene Glycol Dimethyl Ether is utilized in the formulation of pesticides and herbicides, helping to dissolve active ingredients for effective plant protection.

In the textile industry, it serves as a solvent for dyes and printing inks, facilitating vibrant and even coloration.
Dipropylene Glycol Dimethyl Ether is employed in the automotive industry in various products, including paints, coatings, adhesives, and cleaning agents.
Dipropylene Glycol Dimethyl Ether finds application in the formulation of industrial and household cleaning products, improving solvency and effectiveness.

Dipropylene Glycol Dimethyl Ether serves as a solvent and dispersion medium in the production of resins, including epoxy resins and polyurethane resins.
Dipropylene Glycol Dimethyl Ether is used in surface coatings, such as wood coatings and metal coatings, aiding in film formation and adhesion.

Dipropylene Glycol Dimethyl Ether is employed in the pharmaceutical industry as a solvent or co-solvent in certain formulations, aiding in drug delivery.
Dipropylene Glycol Dimethyl Ether serves as a solvent in the formulation of agricultural chemicals, ensuring efficient delivery of herbicides, insecticides, and fungicides.

Dipropylene Glycol Dimethyl Ether finds application in the fragrance and perfume industry as a solvent for aromatic compounds, aiding in formulation stability.
Dipropylene Glycol Dimethyl Ether is used in resin casting applications, allowing for the pouring and curing of resins in molds.

Dipropylene Glycol Dimethyl Ether serves as a solvent in extraction processes, facilitating the extraction of essential oils and botanical extracts.
Dipropylene Glycol Dimethyl Ether finds use as a processing aid in polymer manufacturing and processing, enhancing melt flow and processability.
Dipropylene Glycol Dimethyl Ether has been investigated as a potential fuel additive or component in alternative fuels, owing to its favorable properties.

Dipropylene Glycol Dimethyl Ether can be used as a solvent or reagent in laboratory and research applications, contributing to various chemical processes.
Dipropylene Glycol Dimethyl Ether serves as a carrier solvent for the delivery of active ingredients in certain agricultural and pharmaceutical formulations.

Dipropylene Glycol Dimethyl Ether finds application in the formulation of industrial degreasers, effectively removing oils and greases from surfaces.
Dipropylene Glycol Dimethyl Ether is utilized in the production of specialty chemicals, providing solvency and stability for diverse applications.

Dipropylene Glycol Dimethyl Ether is utilized in the formulation of industrial coatings, providing excellent solvent properties for various coating systems.
Dipropylene Glycol Dimethyl Ether is used as a solvent in the production of wood stains and varnishes, aiding in the even and smooth application of the coating.
Dipropylene Glycol Dimethyl Ether finds application in the formulation of corrosion inhibitors, contributing to the protection of metal surfaces.

Dipropylene Glycol Dimethyl Ether is employed as a solvent in the production of specialty inks, including specialty printing inks and inkjet inks.
Dipropylene Glycol Dimethyl Ether serves as a solvent in the formulation of leather dyes and finishes, enhancing color intensity and adhesion.

Dipropylene Glycol Dimethyl Ether finds use in the production of specialty adhesives, such as those used in electronics assembly and automotive applications.
Dipropylene Glycol Dimethyl Ether is used in the formulation of metalworking fluids, aiding in the lubrication and cooling of metal machining operations.

Dipropylene Glycol Dimethyl Ether is employed as a solvent in the production of textile auxiliaries, contributing to the formulation of dyeing and finishing agents.
Dipropylene Glycol Dimethyl Ether finds application as a solvent in the production of cleaning formulations for industrial and institutional use.
Dipropylene Glycol Dimethyl Ether serves as a solvent for the formulation of oilfield chemicals, aiding in the dissolution and delivery of active components.

Dipropylene Glycol Dimethyl Ether is utilized in the production of specialty detergents, enhancing the solubility and cleaning efficacy of the formulations.
Dipropylene Glycol Dimethyl Ether finds use as a solvent in the production of metal cleaners and degreasers, effectively removing contaminants from metal surfaces.

Dipropylene Glycol Dimethyl Ether is employed as a solvent for the formulation of automotive care products, such as polishes and waxes.
Dipropylene Glycol Dimethyl Ether serves as a solvent in the production of personal care and cosmetic products, including makeup removers and skin cleansers.

Dipropylene Glycol Dimethyl Ether is used in the formulation of air fresheners and household cleaning sprays, aiding in the dispersion of fragrances and cleaning agents.
Dipropylene Glycol Dimethyl Ether finds application as a solvent in the production of resin-based 3D printing materials, contributing to their formulation and performance.

Dipropylene Glycol Dimethyl Ether serves as a solvent for the formulation of specialty chemicals, such as specialty coatings and surface treatments.
Dipropylene Glycol Dimethyl Ether is employed in the production of industrial lubricants and metalworking fluids, improving lubrication and reducing friction.
Dipropylene Glycol Dimethyl Ether finds use as a solvent in the formulation of circuit board cleaners and electronic component maintenance products.

Dipropylene Glycol Dimethyl Ether serves as a solvent for the production of ink remover formulations, aiding in the removal of inks from various surfaces.
Dipropylene Glycol Dimethyl Ether is used in the formulation of wood preservatives, aiding in the penetration and preservation of wood materials.

Dipropylene Glycol Dimethyl Ether finds application as a solvent in the production of construction adhesives and sealants, improving their workability and bonding properties.
Dipropylene Glycol Dimethyl Ether serves as a solvent in the formulation of specialty coatings for optical lenses and displays, contributing to their optical performance.

Dipropylene Glycol Dimethyl Ether is employed in the production of specialty fuels, such as racing fuels and high-performance blends.
Dipropylene Glycol Dimethyl Ether finds use as a solvent in the formulation of household and industrial aerosol products, aiding in the dispersion of active ingredients.


Dipropylene Glycol Dimethyl Ether (Dipropylene Glycol Dimethyl Ether) finds applications in various industries due to its favorable solvent properties.
Some of its common applications include:

Coatings and Paints:
Dipropylene Glycol Dimethyl Ether is used as a solvent in the formulation of coatings and paints, where it enhances solubility, improves flow, and contributes to the leveling of the applied film.

Printing Inks:
Dipropylene Glycol Dimethyl Ether is employed as a solvent in the production of printing inks, aiding in the dissolution of colorants, resins, and other ink components.

Adhesives and Sealants:
Dipropylene Glycol Dimethyl Ether is used as a solvent in the manufacturing of adhesives and sealants, helping to dissolve and disperse various adhesive components.

Cleaning Agents:
Dipropylene Glycol Dimethyl Ether can be found in cleaning agents, such as degreasers and industrial cleaners, due to its ability to dissolve oils, greases, and other contaminants.

Industrial Processes:
Dipropylene Glycol Dimethyl Ether serves as a solvent in various industrial processes, including extraction, reaction media, and as a component in chemical formulations.

Chemical Reactions:
Dipropylene Glycol Dimethyl Ether is used as a reaction medium or solvent in chemical reactions, facilitating the dissolution of reactants and promoting the desired reactions.

Electronics Industry:
Dipropylene Glycol Dimethyl Ether is employed as a solvent for electronic component cleaning, soldering fluxes, and as a carrier solvent for various electronic formulations.

Lithium-ion Batteries:
Dipropylene Glycol Dimethyl Ether finds application as a solvent for the electrolyte in lithium-ion batteries, helping to enhance ion mobility and overall battery performance.

Personal Care Products:
Dipropylene Glycol Dimethyl Ether can be found in certain personal care products, such as cosmetics and skin care formulations, where it functions as a solvent for active ingredients or as a formulation aid.

Pesticides and Herbicides:
Dipropylene Glycol Dimethyl Ether is used as a solvent in the formulation of pesticides and herbicides to dissolve and distribute the active ingredients effectively.

Textile Industry:
Dipropylene Glycol Dimethyl Ether may be used as a solvent in textile dyeing and printing processes, helping to dissolve dyes and aid in their application.

Automotive Industry:
Dipropylene Glycol Dimethyl Ether can be found in automotive-related products, such as paints, coatings, adhesives, and cleaning agents used in the manufacturing and maintenance of vehicles.


In addition to the previously mentioned applications, Dipropylene Glycol Dimethyl Ether (Dipropylene Glycol Dimethyl Ether) has several other uses across different industries.
Here are some additional applications of Dipropylene Glycol Dimethyl Ether:

Resin Manufacturing:
Dipropylene Glycol Dimethyl Ether is utilized as a solvent in the production of various resins, including epoxy resins, acrylic resins, and polyurethane resins.
Dipropylene Glycol Dimethyl Ether helps dissolve and disperse resin components, aiding in the formulation process.

Industrial Cleaning:
Dipropylene Glycol Dimethyl Ether is used in industrial cleaning applications, such as parts washing and degreasing, due to its solvent properties and ability to dissolve oils, greases, and contaminants.

Surface Coatings:
Dipropylene Glycol Dimethyl Ether finds application in surface coating formulations, including wood coatings, metal coatings, and protective coatings.
Dipropylene Glycol Dimethyl Ether contributes to film formation, leveling, and adhesion of the coating to the substrate.

Pharmaceuticals:
Dipropylene Glycol Dimethyl Ether can be used as a solvent or co-solvent in certain pharmaceutical formulations, such as oral suspensions and topical preparations.

Agricultural Chemicals:
Dipropylene Glycol Dimethyl Ether is employed as a solvent in the formulation of agricultural chemicals, including herbicides, insecticides, and fungicides.
Dipropylene Glycol Dimethyl Ether helps solubilize and deliver the active ingredients effectively.

Fragrance and Perfume Industry:
Dipropylene Glycol Dimethyl Ether is sometimes used as a solvent or carrier for fragrances and perfumes, helping to dissolve and disperse aromatic compounds.

Resin Casting:
Dipropylene Glycol Dimethyl Ether is used in resin casting applications, where it serves as a solvent for resins, facilitating the pouring and curing of resin into molds.

Extraction Processes:
Dipropylene Glycol Dimethyl Ether can be utilized as a solvent in extraction processes, such as essential oil extraction or botanical extractions for natural products.

Polymer Processing:
Dipropylene Glycol Dimethyl Ether is employed as a processing aid in polymer manufacturing and processing, helping to enhance melt flow and improve the processability of polymers.

Fuel and Fuel Additives:
Dipropylene Glycol Dimethyl Ether has been investigated as a potential fuel additive or component in alternative fuels due to its favorable properties, such as its low toxicity and high flash point.

Laboratory and Research Applications:
Dipropylene Glycol Dimethyl Ether may find use as a solvent or reagent in various laboratory and research applications, including chemical synthesis, chromatography, and material testing.


It's worth noting that the suitability and specific applications of Dipropylene Glycol Dimethyl Ether can vary depending on factors such as compatibility with other substances, regulatory considerations, and industry-specific requirements.



DESCRIPTION


Dipropylene glycol dimethyl ether (Dipropylene Glycol Dimethyl Ether) is a chemical compound with the molecular formula C8H18O3.
Dipropylene Glycol Dimethyl Ether belongs to the family of glycol ethers and is a clear, colorless liquid with a mild, ether-like odor.
Dipropylene Glycol Dimethyl Ether is composed of two propylene glycol units and one dimethyl ether unit.

Dipropylene Glycol Dimethyl Ether is commonly used as a solvent in various applications, including coatings, paints, inks, cleaners, and industrial processes.
Dipropylene Glycol Dimethyl Ether possesses good solvency for a wide range of substances, including resins, dyes, oils, and greases.

Dipropylene Glycol Dimethyl Ether also has a high boiling point and low volatility, making it suitable for use in high-temperature processes.
As a solvent, Dipropylene Glycol Dimethyl Ether offers advantages such as good stability, low toxicity, low odor, and low viscosity.

Dipropylene Glycol Dimethyl Ether can enhance the flow and leveling properties of coatings and improve the solubility of different components.
Dipropylene Glycol Dimethyl Ether is also used as an intermediate in the synthesis of other chemicals.

Dipropylene Glycol Dimethyl Ether is important to note that Dipropylene Glycol Dimethyl Ether should be handled and stored in accordance with safety guidelines and local regulations.
Consult the safety data sheet (SDS) for specific information on its hazards, handling practices, and recommended precautions.

Dipropylene Glycol Dimethyl Ether (Dipropylene Glycol Dimethyl Ether) is a clear and colorless liquid.
Dipropylene Glycol Dimethyl Ether has a mild, ether-like odor.

Dipropylene Glycol Dimethyl Ether has a molecular weight of approximately 162.23 g/mol.
Dipropylene Glycol Dimethyl Ether has a relatively high boiling point of around 190°C (374°F).

Dipropylene Glycol Dimethyl Ether is soluble in water and many organic solvents.
Dipropylene Glycol Dimethyl Ether exhibits good solvency power for a wide range of substances, including resins and dyes.

Dipropylene Glycol Dimethyl Ether has a low vapor pressure, resulting in low volatility.
Dipropylene Glycol Dimethyl Ether is compatible with various polymers, making it useful in coating formulations.
Dipropylene Glycol Dimethyl Ether is commonly used as a solvent in paints, inks, and industrial applications.

Dipropylene Glycol Dimethyl Ether can act as a coupling agent to enhance the compatibility of different components.
Dipropylene Glycol Dimethyl Ether has good stability and can withstand high-temperature processes.

Dipropylene Glycol Dimethyl Ether is non-corrosive to common metals, such as steel and aluminum.
Dipropylene Glycol Dimethyl Ether exhibits low toxicity, which contributes to its widespread use.

Dipropylene Glycol Dimethyl Ether has low viscosity, allowing for ease of handling and incorporation into formulations.
Dipropylene Glycol Dimethyl Ether is a versatile solvent suitable for both polar and non-polar substances.

Dipropylene Glycol Dimethyl Ether has a flash point above 93°C (199°F), indicating a relatively low flammability risk.
Dipropylene Glycol Dimethyl Ether is stable under normal storage conditions, but prolonged exposure to air and light should be avoided.
Dipropylene Glycol Dimethyl Ether is a hygroscopic liquid, meaning it can absorb moisture from the surrounding environment.

Dipropylene Glycol Dimethyl Ether is chemically stable and does not undergo significant decomposition or reaction under typical conditions.
Dipropylene Glycol Dimethyl Ether is commonly used in the production of printing inks, adhesives, and cleaning agents.

Dipropylene Glycol Dimethyl Ether can improve the flow, leveling, and gloss properties of coatings and paints.
Dipropylene Glycol Dimethyl Ether is compatible with various pigment types and can enhance color development.

Dipropylene Glycol Dimethyl Ether is readily miscible with many organic solvents, facilitating its use in various formulations.
Dipropylene Glycol Dimethyl Ether has a relatively low evaporation rate, allowing for longer open times in coating applications.
Overall, Dipropylene Glycol Dimethyl Ether is a versatile solvent with excellent solvency and stability properties, making it a valuable component in numerous industrial and commercial applications.



PROPERTIES


Physical Properties:

Molecular Formula: C8H18O3
Molecular Weight: 162.23 g/mol
Appearance: Colorless liquid
Odor: Mild, ether-like odor
Density: 0.929 g/cm³ at 25°C
Boiling Point: 166-168°C
Melting Point: -80°C
Flash Point: 50°C (closed cup)
Vapor Pressure: 0.7 mmHg at 25°C
Solubility: Miscible with water and many organic solvents
Viscosity: 2.6 cP at 25°C


Chemical Properties:

Chemical Formula: CH3O(CH2CH2O)2CH3
Chemical Structure: CH3-O-CH2CH2O-CH2CH2-O-CH3
Solubility in Water: Miscible in all proportions
pH: Neutral


Thermal Properties:

Heat of Vaporization: 46.2 kJ/mol at boiling point
Heat of Combustion: -3,650 kJ/mol


Miscellaneous Properties:

Flammability: Dipropylene Glycol Dimethyl Ether is flammable and should be handled with appropriate safety precautions.
Hygroscopicity: Dipropylene Glycol Dimethyl Ether has a low hygroscopicity, meaning it has a low tendency to absorb moisture from the air.
Volatility: Dipropylene Glycol Dimethyl Ether has a moderate volatility, evaporating readily at room temperature.
Evaporation Rate: The evaporation rate of Dipropylene Glycol Dimethyl Ether is moderate.
Dielectric Constant: Dipropylene Glycol Dimethyl Ether has a dielectric constant of approximately 6.5, indicating its electrical insulating properties.



FIRST AID


Inhalation:

If inhaled, remove the affected person from the exposure area to fresh air.
If the person is experiencing difficulty breathing, provide oxygen if available and seek immediate medical attention.
If breathing has stopped, perform artificial respiration and seek immediate medical attention.
Keep the affected person at rest and warm.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected skin area with plenty of soap and water for at least 15 minutes.
If skin irritation or redness occurs, seek medical advice and provide the details of the product.
Contaminated clothing should be thoroughly cleaned before reuse.


Eye Contact:

Flush the eyes with gently flowing water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Remove contact lenses if present and easily removable during rinsing.
Seek immediate medical attention, and provide information about the product to the medical personnel.


Ingestion:

Rinse the mouth with water without swallowing to remove any residual product.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek immediate medical attention, and provide information about the product to the medical personnel.
If medical personnel are not immediately available, contact a poison control center or local emergency services for guidance.


General Measures:

Ensure that individuals providing assistance are protected from exposure to the product.
If necessary, move the affected person to a well-ventilated area.
Provide comfort and reassurance to the affected person.
If symptoms persist or worsen, seek medical advice or consultation.



HANDLING AND STORAGE


Handling:

General Precautions:
Handle Dipropylene Glycol Dimethyl Ether in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.
Use appropriate personal protective equipment (PPE) such as chemical-resistant gloves, safety goggles, and protective clothing to minimize skin and eye contact.
Avoid inhalation of vapors or mists.
If exposure occurs, move to fresh air immediately.

Fire and Explosion Precautions:
Keep away from sources of ignition, including open flames, sparks, and hot surfaces.
Use non-sparking tools and equipment when handling Dipropylene Glycol Dimethyl Ether.
In case of fire, use dry chemical, carbon dioxide (CO2), water spray, or foam to extinguish the flames.

Storage Containers:
Store Dipropylene Glycol Dimethyl Ether in tightly closed containers made of compatible materials, such as stainless steel, high-density polyethylene (HDPE), or glass.
Ensure containers are properly labeled with appropriate safety information.
Store away from incompatible substances and sources of heat or ignition.

Storage Conditions:
Store Dipropylene Glycol Dimethyl Ether in a cool, dry, and well-ventilated area, away from direct sunlight.
Maintain storage temperatures between 10°C and 40°C (50°F - 104°F) to ensure product stability.
Avoid exposure to extreme temperatures and protect from freezing.

Handling Procedures:
Use proper handling equipment, such as pumps or closed systems, to transfer Dipropylene Glycol Dimethyl Ether.
Avoid splashing or spilling the product. Clean up spills promptly and dispose of waste materials properly according to local regulations.
Do not smoke, eat, or drink while handling Dipropylene Glycol Dimethyl Ether.
Wash hands thoroughly with soap and water after handling the product.

Compatibility:
Keep Dipropylene Glycol Dimethyl Ether away from strong oxidizing agents, strong acids, and alkalis.
Avoid contact with reactive materials that can undergo hazardous reactions.

Storage:

Segregation:
Store Dipropylene Glycol Dimethyl Ether away from incompatible materials, including strong oxidizers, acids, and bases.
Separate it from reactive substances to prevent accidental reactions.

Ventilation:
Ensure proper ventilation in storage areas to maintain air quality and minimize the buildup of vapors.

Containment:
Store Dipropylene Glycol Dimethyl Ether in suitable secondary containment, such as spill trays or bunded areas, to prevent leaks or spills from spreading.

Labeling:
Clearly label storage containers with product information, including name, hazards, and safety precautions.
Ensure labels are intact, legible, and up to date.

Fire Protection:
Store Dipropylene Glycol Dimethyl Ether away from sources of ignition, flames, and heat.
Implement appropriate fire suppression systems and equipment in storage areas.

Handling Equipment:
Use proper handling equipment, such as pumps or drum faucets, to transfer Dipropylene Glycol Dimethyl Ether from storage containers.



SYNONYMS


Dipropylene Glycol Dimethyl Ether
Dipropylene Glycol Dimethyl EtherA (Dipropylene Glycol Dimethyl Ether Acetate)
Dipropylene Glycol Methyl Ether
Dipropylene Glycol Monomethyl Ether
1-(2-Methoxymethylethoxy)-2-propanol
2-(2-Methoxymethylethoxy)-1-methylethanol
DMM
DPM
DPGME
Methoxypropoxypropanol
Methyl Oxybispropanol
Methyl Dipropylene Glycol Ether
Methyl Dipropylene Glycol Monomethyl Ether
Methyl Oxydipropanol
Methyl Proxylpropyl Cellosolve
Solvenon® DPM
Dowanol® DPM
Proxylpropyl Cellosolve
Bis(2-methoxypropyl) methyl ether
Methoxypropyl Methoxypropyl Ether
2,2'-Dipropoxypropane
DMPM
DPMME
Methoxypropyl Methyl Ether
Methyl Propyleneglycol Ether
2-(2-Methoxypropoxy)-1-methylethanol
2-Methoxypropoxy-1-methyl-1-ethanol
Methoxypropoxypropyl methyl ether
Methoxypropylene Dimethyl Ether
DPGMME
Propylene Glycol Methyl Ether Dipropylene Glycol Ether
Methoxypropoxypropanol
Dipropylene Glycol Ether Methyl Ether
DPEM
Methyl Dipropylene Glycol Propyl Ether
Methoxypropyl Propylene Glycol Ether
2-(2-Methoxypropoxy)propan-1-ol
Propyl Diglycol Methyl Ether
DPMME2
Methoxypropoxypropyl Methoxypropyl Ether
Methyl Dipropylene Glycol Proxyl Ether
Methoxypropyl Proxylpropyl Ether
Methyl 2-(2-Methoxypropoxy)propan-1-ol
Methyl Diglycol Methyl Ether
2-(1-Methoxy-2-propoxy)propan-1-ol
Methoxypropyl Diglycol Ether
Propyl Oxybispropanol Methyl Ether
Methyl 2-(2-Methoxy-1-methylethoxy)propan-1-ol
Methoxypropyl Propanediol Ether
Propylene Glycol Monomethyl Ether Dipropylene Glycol Ether
2-(2-Methoxypropoxy)-propanol
Methoxypropoxypropanol
Methoxypropoxy-2-propanol
Methoxypropoxypropan-2-ol
Methoxypropoxymethyl propanol
1-(2-Methoxypropoxy)-2-propanol
1-Methoxy-2-(2-methoxypropoxy)propane
Methyl Dipropylene Glycol Ether
Methyl Dipropylene Glycol Dimethyl Ether
Methyl Dipropylene Glycol Methyl Ether
Methyl Dipropylene Glycol Proxyl Ether
Methoxypropyl Dipropylene Glycol Ether
Methoxypropyl Dipropylene Glycol Dimethyl Ether
Methoxypropyl Dipropylene Glycol Methyl Ether
Methoxypropyl Dipropylene Glycol Proxyl Ether
Dipropylene Glycol Methoxypropyl Ether
Dipropylene Glycol Methoxypropyl Ether Acetate
1-Methoxy-2-propoxypropan-1-ol
Methyl Oxypropoxypropanol
Methyl Oxypropoxypropanol Acetate
2-(2-Methoxypropoxy)-1-methylpropan-1-ol
Methyl 2-(2-methoxypropoxy)propanoate
Methyl Oxypropoxypropyl Ether
Methyl Oxypropyl Diglycol Ether
Methyl Oxypropyl Proxyl Ether

DIPROPYLENE GLYCOL DIMETHYL ETHER
Dipropylene Glycol Dimethyl Ether
CAS Number: 34590-94-8



APPLICATIONS


Dipropylene Glycol Dimethyl Ether is an aprotic (no hydroxyl functionality), that can be used in protonsensitive systems such as water-based polyurethane coatings.
Furthermore, Dipropylene Glycol Dimethyl Ether can also be used as an azeotroping solvent for esterification reactions.

Dipropylene Glycol Dimethyl Ether has excellent stability, solvency, and coupling performance.
Moreover, Dipropylene Glycol Dimethyl Ether provides excellent compatibility with a wide range of agricultural formulations and cleaning products.

Dipropylene Glycol Dimethyl Ether is mainly used for coating resins, cleaners, textiles, cosmetics, automotive construction application.
Besides, Dipropylene Glycol Dimethyl Ether is used in hydraulic fluids and as a solvent.


Uses of Dipropylene Glycol Dimethyl Ether:

Cleaners
Textiles
Cosmetics
Resins
Coating formulation and application
Industrial, automotive and architectural coatings
Power steering fluids
Transmission fluids
Brake fluids
Fuel injector cleaners
Gas treatments
Leak stoppers
Auto Products
Commercial / Institutional
Hobby/Craft
Home Maintenance
Inside the Home
Landscaping/Yard
Personal Care
Pesticides
Pet Care


Dipropylene Glycol Dimethyl Ether has favorable enviornmental profile.
In addition, Dipropylene Glycol Dimethyl Ether has superior performance for end use applications.
Dipropylene Glycol Dimethyl Ether formulations may require less Performance solvent than other chemicals.

Dipropylene Glycol Dimethyl Ether is an aprotic solvent for use in water-based polyurethane/isocyanate coating systems.


Dipropylene Glycol Dimethyl Ether provides:

Active solvency for solvent-based coatings.
Water removal agent useful in esterification reactions for the production of exceptionally clear resins.
Powerful paint-stripping formulation when used in combination with small amounts of protic solvent.
Aproticity, strong solvency, and coupling performance provide for compatibility with a wide range of agricultural formulations.
Effective for printed circuit board cleaners developed to reduce CFC emissions.
Stability over a wide pH range allows for use in strongly acidic or alkaline cleaners.
Aprotic solvent for use on proton-sensitive systems such as water-based polyurethane coatings.


Dipropylene Glycol Dimethyl Ether is a colorless liquid with a mild, pleasant odor.

Dipropylene Glycol Dimethyl Ether is completely miscible with most common organic solvents.
However, Dipropylene Glycol Dimethyl Ether has limited solubility in water.
Dipropylene Glycol Dimethyl Ether has no hydroxyl functionality.

Dipropylene Glycol Dimethyl Ether is an inert, aprotic solvent and can be used in proton sensitive systems.
More to that, Dipropylene Glycol Dimethyl Ether is not listed as a Hazardous Air Pollutant, has low toxicity, and offers an alternative to solvents being phased out as a result of the Clean Air Act.
Due to its chemical stability and the absence of reactive groups, Dipropylene Glycol Dimethyl Ether can also be used as an inert reaction medium, e.g. for reactions with alkali and alkaline-earth metals (Grignard reactions), polymerizations etc.

Dipropylene Glycol Dimethyl Ether is used in solvent-based coatings and water-based polyurethane/ isocyanate coating systems.
Additionally, Dipropylene Glycol Dimethyl Ether is used as environmentally friendly substitute for NMP (N-methyl pyrrolidone) e.g as as coalescing agent in water based polyurethane dispersions.
Dipropylene Glycol Dimethyl Ether is also used as a solvent for wood and furniture coatings as well as a solvent for hardeners.

Dipropylene Glycol Methyl Ether is a colorless liquid with a mild and pleasant odor.
Further to that, Dipropylene Glycol Dimethyl Ether is a solvent used in paints, pastes, dyes, resins, brake fluids and inks, and in making cosmetics.

Dipropylene Glycol Dimethyl Ether is used in method for evaluating profile of ink compound and manufacturing organic light emitting device comprising same.
Furthermore, Dipropylene Glycol Dimethyl Ether is aprotic solvent for use on proton-sensitive systems such as water-based polyurethane coatings.
Dipropylene Glycol Dimethyl Ether can be used as aprotic solvent for use on proton-sensitive systems such as water-based polyurethane coatings.

Dipropylene Glycol Dimethyl Ether is a powerful solvent for a vast range of organic compounds.
Moreover, Dipropylene Glycol Dimethyl Ether is used as a solvent in the manufacture of water-based coatings and DPGME is also used as a coalescing agent for water based paints and inks.
Dipropylene Glycol Dimethyl Ether is an ingredient in a wide variety of industrial products including cleaning agents, cosmetic agents,
detergent/wetting agents, sanitary/disinfectant cleaners, solvent for paints/varnished/inks, and stripper/degreasers.

Dipropylene Glycol Dimethyl Ether is an organic solvent with a variety of industrial and commercial uses.
Besides, Dipropylene Glycol Dimethyl Ether finds use as a less volatile alternative to propylene glycol methyl ether and other glycol ethers.
Dipropylene Glycol Dimethyl Ether is a colorless liquid with a mild odor.

Dipropylene Glycol Dimethyl Ether is also used in a wide variety of household and commercial cleaning products including glass, surface, paintbrush, carpet, and all-purpose cleaners, floor polish, industrial degreasers, aluminium brighteners, and rust removers.
In addition, Dipropylene Glycol Dimethyl Ether is also used in chemicals for the oil production and drilling industry.
In the U.S. in 1999, Dipropylene Glycol Dimethyl Ether was used as follows: 58% paints/coatings/inks, 28% cleaners, 10% DPGME acetate production, and 3 % miscellaneous production.


Key Features of Dipropylene Glycol Dimethyl Ether:

Aproticity
High solvency
Coupling ability
Coalescing ability
Water removal
Powerful diluent
Thermal and chemical stability
Low odor
Moderate evaporation rate
Low toxicity



DESCRIPTION


Dipropylene Glycol Dimethyl Ether is a clear, colorless, combustible liquid with a slight ether odor.
Additionally, Dipropylene Glycol Dimethyl Ether is completely soluble in water, and has moderate volatility. DPM is a propylene oxide-based, or P-series, glycol ether.

Dipropylene Glycol Dimethyl Ether is an organic solvent with a variety of industrial and commercial uses.
More to that, Dipropylene Glycol Dimethyl Ether finds use as a less volatile alternative to propylene glycol methyl ether and other glycol ethers.
Dipropylene Glycol Dimethyl Ether is typically a mixture of four isomers.

Dipropylene Glycol Dimethyl Ether is a propylene oxide-based diether and is hygroscopic(attracts water).
Eye contact with Dipropylene Glycol Dimethyl Ether may cause slight irritation, although corneal injury is unlikely.
Prolonged skin contact is not likely to cause significant irritation or result in absorption ofharmful amounts.

Dipropylene Glycol Dimethyl Ether is an inert solvent and well suited as a non-toxic alternative to NMP and NEP in paints & coatings applications, especially for waterborne PU-dispersions and 2P-formulations.

Dipropylene Glycol Dimethyl Ether is a colorless liquid with a mild odor.
Further to that, Dipropylene Glycol Dimethyl Ether is apropylene oxide-based diether and ishygroscopic (attracts water).
Dipropylene Glycol Dimethyl Ether is an aprotic solvent, meaning it is relatively inert because it does not have hydroxyl groups that readily donate or accept protons.

Dipropylene Glycol Dimethyl Ether liquid and vapor are combustible.
Furthermore, Dipropylene Glycol Dimethyl Ether is stable under recommended storage conditions.

Store Dipropylene Glycol Dimethyl Ether in carbon steel, stainless steel, or phenolic-lined steel drums.
Do not store in aluminum, copper, galvanized steel, or galvanized iron.

Dipropylene Glycol Dimethyl Ether can decompose at elevated temperatures.
Generation of gas during decomposition can cause pressure in closed systems.

Decomposition products depend on temperature, air supply, and the presence of other materials, but can include aldehydes, ketones, organic acids, and other compounds.
Dipropylene Glycol Dimethyl Ether is incompatible with strong acids, strong bases, and strong oxidizers and contact should be avoided.

Dipropylene Glycol Dimethyl Ether is volatile, and will evaporate from products containing it.
However, because Dipropylene Glycol Dimethyl Ether is moderately soluble in water, once introduced, it has a tendency to remain in water.
Dipropylene Glycol Dimethyl Ether has minimal tendency to bind to soil or sediment.

Dipropylene Glycol Dimethyl Ether is unlikely to persist in the environment.
Moreover, Dipropylene Glycol Dimethyl Ether is inherently biodegradable, which suggests the chemical will be removed from water and soil environments, including biological waste water treatment plants.
Dipropylene Glycol Dimethyl Ether is not likely to accumulate in the food chain (bioconcentration potential is low), and it is practically nontoxic to fish and other aquatic organisms on an acute basis.

Dipropylene Glycol Dimethyl Ether is unique among propylene oxide-based solvents in that it is aprotic (no hydroxyl functionality).
As a result, Dipropylene Glycol Dimethyl Ether is relatively inert and can be used in proton sensitive systems such as water-based polyurethane coatings.

Dipropylene Glycol Dimethyl Ether can also be used as an azeotroping solvent for esterification reactions.
And with its excellent stability, solvency, and coupling performance, Dipropylene Glycol Dimethyl Ether provides excellent compatibility with a wide range of agricultural formulations and cleaning products.

Dipropylene Glycol Dimethyl Ether is an aprotic and inert solvent used in water-based polyurethane coatings with molecular formula C8H18O3 and a molecular weight of 162.23 g/mol.
Besides, Dipropylene Glycol Dimethyl Ether is also known as 1-methoxy-3-(3-methoxypropoxy)propan.
Dipropylene Glycol Dimethyl Ether is a colourless liquid with mild odour, miscible with most common organic solvents but with limited solubility in water.



PROPERTIES


Boiling point: 190 °C (374 °F; 463 K)[1]
Solubility in water: Miscible
Hazards Flash point: 75 °C (167 °F; 348 K)[1]
Boiling Point (°C @760mmHg): 175
Chemical Name: Dipropylene glycol dimethyl ether
Density (25°C) at lb/gal (g/cc): 7.5 (0.899)
Evaporation Rate (n-butyl acetate=1.0): 0.13
Flash Point, Closed Cup: 65 °C
Freezing Point °F(°C): Hansen Solubility Parameter, dD (joules/cm3)1/2: 14.9
Hansen Solubility Parameter, dH (joules/cm3)1/2: 3.8
Hansen Solubility Parameter, dP (joules/cm3)1/2: 2.1
Low Vapor Pressure (Solubility in Water (25°C): 35 wt%
Solubility Water in (25°C): 4.5 wt%
Specific Gravity (25°C): 0.902
Surface Tension (1% actives, 25 °C): 26.3 dynes/cm
Vapor Pressure (mmHg @ 20°C): 0.55
Viscosity (25°C): 1 cP
Molecular Weight: 162.23
XLogP3: 0.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 6
Exact Mass: 162.125594432
Monoisotopic Mass: 162.125594432
Topological Polar Surface Area: 27.7 Ų
Heavy Atom Count: 11
Formal Charge: 0
Complexity: 85.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID


General advice:

First Aid responders should pay attention to self-protection and use the recommended protective clothing (chemical resistant gloves, splash protection).
If potential for exposure exists refer to safety sheet for specific personal protective equipment.


Inhalation:

Move person to fresh air; if effects occur, consult a physician.


Skin contact:

Remove material from skin immediately by washing with soap and plenty of water.
Remove contaminated clothing and shoes while washing.
Seek medical attention if irritation persists.

Wash clothing before reuse.
Discard items which cannot be decontaminated, including leather articles
such as shoes, belts and watchbands.


Eye contact:

Flush eyes thoroughly with water for several minutes.
Remove contact lenses after the initial 1-2 minutes and continue flushing for several additional minutes.
If effects occur, consult a physician, preferably an ophthalmologist.


Ingestion:

If swallowed, seek medical attention.
Do not induce vomiting unless directed to do so by medical personnel.


Most important symptoms and effects, both acute and delayed:

Aside from the information found under Description of first aid measures (above), any additional important symptoms and effects are described in Safety sheet.


Indication of any immediate medical attention and special treatment needed:
Notes to physician:

No specific antidote.
Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.



HANDLING AND STORAGE


Precautions for safe handling:

Avoid contact with eyes.
Wash thoroughly after handling.
Containers, even those that have been emptied, can contain vapors.

Do not cut, drill, grind, weld, or perform similar operations on or near empty containers.
Spills of these organic materials on hot fibrous insulations may lead to lowering of the autoignition temperatures possibly resulting in spontaneous combustion.
Keep away from heat, sparks and flame.


Conditions for safe storage:
Store in the following material(s): Carbon steel. Stainless steel.

Phenolic lined steel drums.
Do not store in: Aluminum. Copper. Galvanized iron. Galvanized steel.


Technical measures:

Highly flammable.
Avoid contact with high temperature objects, spark, and strong oxidizing agents.
Use withlocal exhaust ventilation.

Precautions:

Do not rough handling containers, such as upsetting, falling, giving a shock, and dragging Prevent leakage, overflow, andscattering.
Not to generate steam and dust in vain.
Seal the container after use.

After handling, wash hands andface, andthen gargle
Deny unnecessary entry of non-emergency personnel to the handling area

Safety handling precautions:

Take necessary action to avoid static electricity discharge (which might cause ignition of organic vapors).
Use personal protective equipment as required.
Avoid contact with skin, eyes or clothing.



SYNONYMS


Dipropylene glycol dimethyl ether; DIPROPYLENE GLYCOL DIMETHYL ETHER
DİPROPİLEN GLİKOL DİMETİL ETER; DİPROPİLEN glikol dimetil eter
dipropilen glikol dimetil eter ; dipropilen glikol dimetil ether
dipropilen glycol dimetil eter
dimetil eter Dipropylene glycol monomethyl ether; Dipropyleneglycol methyl ether
Dipropylene glycol dimethyl ether
DPGME; Dipropyleether; 89399-28-0; 1,2'-oxydipropanol dimethyl ether
2-METHOXY-1-[(1-METHOXYPROPAN-2-YL)OXY]PROPANE; Propanemethoxy-1-methylethoxy)-
1-methoxy-2-(2-methoxypropoxy)propane; 2-(2-Hydroxypropoxy)propan-1-ol dimethyl ether;dimethylether; SCHEMBL77962
2-methoxy-1-(1-methoxypropan-2-yloxy)propane
Propane,2-methoxy-1-(2-methoxyDipropylene Glycol Dimethyl Ether (mixture of isomers)
Di(propylene glycol) dimethyl ether; mixture of isomers; dipopilen dipropilen glikol; diproplen glikol dimetyl ether
dipropylene glycol dimetyl ether; Dipropylene glycol dimethyl ether
DIPRDIMETHYL ETHER; DİPROPİLEN GLİKOL DİMETİL ETER; DİPROPİLEN GLİKOL
dipropilen glikol dimetil eter; dipropilen gdipropilen glikol dimetil ether
dipropilen glycol dimetil eter ; dimetil eter ; dipropilen glycol
Dipropylene glycol mDipropyleneglycol methyl ether; Dipropylene glycol dimethyl ether; DPGME
Dipropylene glycol dimethyl ether; 89399-28-0; dimethyl ether; 2-METHOXY-1-[(1-METHOXYPROPAN-2-YL)OXY]PROPANE
Propane, 2-methoxy-1-(2-methoxy-1-methylethoxymethoxypropoxy)propane
2-(2-Hydroxypropoxy)propan-1-ol dimethyl ether
Dipropylenglycol dimethylether
SCHEMBL7796methoxypropan-2-yloxy)propane; Propane,2-methoxy-1-(2-methoxy-1-methylethoxy)-
Dipropylene Glycol Dimethyl Ether (mDi(propylene glycol) dimethyl ether
mixture of isomers
dipopilen glikol dimetil eter; dipropilen glikol
diproplen glidipropylene glycol dimethyl ether; dipropylen glycol dimethyl ether
dipropilene glycol dimetyl eter; DİPROPİLEN GLİKDİPROPİLEN GLİKOL
DIPROPYLEN GLYCOL DIMETHYL ETHER; DİPROPYLEN GLYCOL DİMETHYL ETHER
DİPROPİLEN GLİKDİPROPYLEN GLYCOL; Dipropylene Glycol Dimethyl Ether
Dipropylene glycol dimethyl ether; Bs(methoxypropyl) ether; dimethyl ether
Dipropylene glycol monomethyl ether; Dipropyleneglycol methyl ether
DPGME; Dipropylene glycol dimethyl 1,2'-oxydipropanol dimethyl ether
2-METHOXY-1-[(1-METHOXYPROPAN-2-YL)OXY]PROPANE; Propane, 2-methomethylethoxy)-
1-methoxy-2-(2-methoxypropoxy)propane; 2-(2-Hydroxypropoxy)propan-1-ol dimethyl ether
DipropylenglySCHEMBL77962; 2-methoxy-1-(1-methoxypropan-2-yloxy)propane
Propane,2-methoxy-1-(2-methoxy-1-methylethoxy)-; DDimethyl Ether (mixture of isomers)
Di(propylene glycol) dimethyl ether; mixture of isomers
dipopilen glikol dimetil eterdiproplen glikol dimetyl ether
dipropylene glycol dimetyl ether; dipropylene glycol dimethyl ether
dipropylen glycol dimethyglycol dimetyl eter; DİPROPİLEN GLİKOL DİMETİL ETER; DİPROPİLEN GLİKOL
DIPROPYLEN GLYCOL DIMETHYL ETHER; DİPDİMETHYL ETHER
DİPROPİLEN GLİKOL DİMETİL ETER; DİPROPYLEN GLYCOL; Dipropylene glycol dimethyl ether
Dipropylene GBs(methoxypropyl) ether; Dipropylene glycol dimethyl ether; 1-Methoxy-2-((1-methoxypropan-2-yl)oxy)propane
Di(propylenether;Dipropylene glycol dimethyl ether; 1-Methoxy-2-((1-methoxypropan-2-yl)oxy)propane
Di(propylene glycol) dimethyl eglycol dimethyl ether; DIPROPYLENE GLYCOL DIMETHYL ETHER
DİPROPİLEN GLİKOL DİMETİL ETER; DİPROPİLEN GLİKOLdimetil eter; dipropilen glikol dimetil eter
dipropilen glikol dimetil ether; dipropilen glycol dimetil eter
dimetil eter ;Dipropylene glycol monomethyl ether; Dipropyleneglycol methyl ether
Dipropylene glycol dimethyl ether; DPGME; Dipropyleether; 89399-28-0; 1,2'-oxydipropanol dimethyl ether
2-METHOXY-1-[(1-METHOXYPROPAN-2-YL)OXY]PROPANE; Propanemethoxy-1-methylethoxy)-; 1-methoxy-2-(2-methoxypropoxy)propane
2-(2-Hydroxypropoxy)propan-1-ol dimethyl ether;dimethylether; SCHEMBL77962; 2-methoxy-1-(1-methoxypropan-2-yloxy)propane
Propane,2-methoxy-1-(2-methoxyDipropylene Glycol Dimethyl Ether (mixture of isomers); Di(propylene glycol) dimethyl ether; mixture of isomers; dipopilen dipropilen glikol; diproplen glikol dimetyl ether.
89399-28-0
Propane, 2-methoxy-1-(2-methoxy-1-methylethoxy)-
2-(2-methoxypropoxy)propan-1-ol
Dipropylene glycol methyl ether
13588-28-8
2-(2-METHOXYPROPOXY)-1-PROPANOL
1-Propanol, 2-(2-methoxypropoxy)-
2-(2-methoxypropoxy)propanol
12002-25-4
Glycol Ether DPM
SCHEMBL16073
Glycol Ether DPM Reagent Grade
dipropyleneglycol monomethyl ether
DTXSID80864425
MFCD19707082
AKOS037648698
NCGC00090688-04
BS-15252
CS-0154037
FT-0625302
D81108
J-019668
J-520393
Q2954819
59X1IJT82G
2-(2-Hydroxypropoxy)propan-1-ol dimethyl ether
1,2'-oxydipropanol dimethyl ether
Propane,2-methoxy-1-(2-methoxy-1-methylethoxy)-
UNII-59X1IJT82G
Dipropylenglycol dimethylether
SCHEMBL77962
DTXSID00274229
MFCD00210047
AKOS015901516
CS-0211609
2-methoxy-1-(1-methoxypropan-2-yloxy)propane
2-Methoxy-1-(2-methoxy-1-methylethoxy)propane
2-Methoxy-1-((1-methoxypropan-2-yl)oxy)propane
J-002522
Q27261724
DIPROPYLENE GLYCOL DIMETHYL ETHER ( DIPROPYLENEGLYCOLDIMETHYLETHER)
Dimethoxy dipropyleneglycol; BIS(METHOXYPROPYL) ETHER; DIPROPYLENE GLYCOL DIMETHYL ETHER; PROGLYDE(TM) DMM; dipropyleneglycoldimethylether,mixtureofisomers; oxybis(methoxy-propan; DI(PROPYLENE GLYCOL) DIMETHYL ETHER, 99.1+%, MIXTURE OF ISOMERS; Propane, oxybismethoxy-; Dipropylenglykoldimethylether; Dimethoxy dipropyleneglycol; DPDME; DPGDME; Bis(methoxypropyl) ether, Proglyde(R) DMM CAS NO:111109-77-4
DIPROPYLENE GLYCOL METHYL ETHER


CAS Number: 34590-94-8
ChEMBL: ChEMBL3182921
ChemSpider: 23783
EC Number: 252-104-2
PubChem CID: 22833331
UNII: RQ1X8FMQ9N

Dipropylene glycol methyl ether is a colorless liquid with a weak odor.
Dipropylene glycol monomethyl ether is a clear, colourless liquid with a faint ether-like odour.
Dipropylene glycol monomethyl ether is soluble in water and has moderate volatility.

Dipropylene glycol monomethyl is produced by reacting propylene oxide with methanol using a catalyst.
Dipropylene glycol monomethyl ether is a mixture of four structural isomers:
1-(2-methoxypropoxy)propanol-2
1-(2-methoxy-1-methylethoxy)propanol-1
2-(2-methoxypropoxy)propanol-1
2-(2-methoxy-1-methylethoxy)propanol-1.

Dipropylene Glycol Monomethyl Ether is a colorless and transparent liquid.
Dipropylene glycol monomethyl ether can be used as a solvent in water-based paints and screen-printing inks.
Dipropylene glycol monomethyl ether can also be used as the coupling agent (often mix) of dilute aqueous coatings.

What is Dipropylene glycol methyl ether)?
Dipropylene glycol monomethyl ether is a propylene oxide-based/P series glycol ether and has the formula C7H16O3.
Dipropylene glycol methyl ether is a clear, colourless, viscous liquid which has a slight ether odour.
Dipropylene glycol methyl ether is completely soluble in water and is miscible with a number of organic solvents, for example ethanol, carbon tetrachloride, benzene, petroleum ether and monochlorobenzene.
Dipropylene glycol methyl ether is also practically non- toxic and hygroscopic, and thus lends itself well to commercial and industrial use.

How is Dipropylene glycol methyl ether produced?
Dipropylene glycol monomethyl ether is produced by the reaction of propylene oxide with methanol using a catalyst.

How is Dipropylene glycol methyl ether stored and distributed?
Dipropylene glycol monomethyl ether is stored in mild steel and /or stainless steel tanks and/or drums and can be transported by bulk vessels or tank trucks.
Dipropylene glycol methyl ether should be stored away from heat and sources of ignition in a cool and well-ventilated area.
Dowanol DPM has a specific gravity of 0.95 and a flashpoint of 75oC (closed cup) and is not regulated for any form of transport.

What is Dipropylene Glycol Methyl Ether Used For?
Dipropylene glycol monomethyl ether is a very useful industrial and commercial chemical.
One of its main commercial uses is as a solvent for paints, varnishes, inks, strippers, and degreasers.
Dipropylene glycol methyl ether is also utilised as a coalescing agent for water-based paints and inks where it promotes polymer fusing during the drying process.
Dipropylene glycol methyl ether is also a component of wood and coil coatings, as well as coatings used in the automotive industry, industrial maintainence, and metal finishing.
Dipropylene glycol methyl ether is also a component of hydraulic fluids and industrial degreasers and is a chemical additive in the oil production and drilling industry.
Dipropylene glycol methyl ether is a very useful chemical building block in the manufacture of many products.
This is due to its reaction with acids, forming esters and oxidising agents which produce aldehydes, carboxylic acids and alkali metals therefore creating alcoholates and acetals.

Dipropylene glycol methyl ether is this flexibility that supports the use of DPM across a range of industries and therefore makes it a component of many household items that people use every day.
Dipropylene glycol methyl ether is found in ceiling and wall paints and in many common cleaners including glass and surface cleaners, paint-brush cleaners, all-purpose cleaners, carpet cleaners and disinfectant cleaners.
Dipropylene glycol methyl ether is also found in cosmetics where it provides emollient properties and product stabilisation as well as floor and aluminium polish, leather and textile dyes, rust removers and pesticides where it acts as a stabiliser.
Dipropylene glycol methyl ether is also a chemical intermediate in the production of Dipropylene glycol monomethyl ether acetate or DPMA.

Product Number of Dipropylene glycol monomethyl ether
Purity / Analysis Method: >98.0%(GC)
Molecular Formula / Molecular Weight: C7H16O3 = 148.20
Physical State (20 deg.C): Liquid
CAS RN: 34590-94-8
PubChem Substance ID: 87567626
SDBS (AIST Spectral DB): 7945
Merck Index (14): 3344
MDL Number: MFCD00059604



Dipropylene glycol monomethyl ether is an organic solvent with a variety of industrial and commercial uses.
Dipropylene glycol monomethyl ether finds use as a less volatile alternative to propylene glycol methyl ether and other glycol ethers.
The commercial product is typically a mixture of four isomers.

Uses of Dipropylene glycol monomethyl ether
Cleaners
Resins
Coating formulation and application
Industrial, automotive and architectural coatings
Benefits
Versatile
Wide range of applications
Extensive combination of physical and performance properties

Applications of Dipropylene glycol monomethyl ether
Architectural coatings
Auto OEM
Auto refinish
Automotive
Building materials
Commerical printing inks
General industrial coatings
Graphic arts
Janitorial & household cleaners
Marine
Paints & coatings
Protective coatings
Wood coatings

Product Detail Product Specification Safety Information Citations (0)
Glentham CodeGK6793
CAS RN34590-94-8
EC Number252-104-2
Storage Temperature+20°C
Shipping TemperatureAmbient
Harmonised Tariff Code29094980

Physical Description
Dipropylene glycol methyl ether is a colorless liquid with a weak odor.
Colorless liquid with a mild, ether-like odor.
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.
Colorless liquid with a mild, ether-like odor.

AS number: 34590–94–8

NIOSH REL: 100 ppm (600 mg/m3) TWA, 150 ppm (900 mg/m3)
Current OSHA PEL: 100 ppm (600 mg/m3)

Description of Substance: Colorless liquid with a mild, ether-like odor.
LEL(@392 F): 1.1% (10% LEL(@392 F), 1,100 ppm)
Basis for original (SCP) IDLH: No acute toxicity data are available on which to base an IDLH for dipropylene glycol methyl ether.
This substance is low in toxicity by inhalation.
Therefore, for this draft technical standard, respirators have been selected on the basis of the assigned protection factor afforded by each device up to a concentration of 50 × the OSHA PEL of 100 ppm (i.e., 5,000 ppm); only the “most protective” respirators are permitted for use in concentrations exceeding 5,000 ppm.
Concentrations above 5,000 ppm are unlikely to be encountered in the workplace because of the high boiling point and low vapor pressure of this substance.

Applications of Dipropylene Glycol Monomethyl Ether
Dipropylene glycol monomethyl ether is primarily used as a solvent in paints, varnishes, printing inks and strippers and in coatings for automotive and architectural applications, wood and coil coatings and metal finishing.
Dipropylene glycol monomethyl ether is also used as a coalescent agent in water-based paints and inks where it serves to promote polymer fusion during the drying process, as a chemical building block for the production of dipropylene glycol monomethyl ether acetate, and as a chemical additive in the oil and drilling industry.

Dipropylene glycol monomethyl ether is found in a wide range of household and industrial cleaners including all-purpose cleaners, glass and other surface cleaners, paint brush cleaners, disinfectants and carpet cleaners.
Dipropylene glycol monomethyl ether is also used as a coupling agent in fabric dyes; as a solvent, coupler, emollient and stabilizer in cosmetic products; and as a stabilizer in pesticides and herbicides.

Storage and Handling OF Dipropylene glycol monomethyl ether
Dipropylene glycol monomethyl should be stored in a cool, well-ventilated place away from sources of ignition and static discharge.
Dipropylene glycol monomethyl ether must be isolated from incompatible materials such as strong oxidizing and reducing agents, alkali metals and nitrides.

Dipropylene glycol monomethyl is a mild irritant to the skin and eyes.
Excessive inhalation may cause irritation to the respiratory tract and drowsiness.
Such risks should be managed by engineering controls, adequate ventilation and by the use of approved personal protective equipment including gloves, clothing and safety goggles and the use of respirators where appropriate to the task being carried out.
All handling should be carried out in a chemical fume hood.

Product identifiers OF Dipropylene glycol monomethyl ether
Product name : Dipropylene glycol monomethyl ether
Product Number : 484253
REACH No. : A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No. : 34590-94-8

Physical and chemical properties of Dipropylene glycol monomethyl ether
Physical state:liquid
Color: colorless
Odor: mild
Melting point/freezing point
Melting point/range: -83 °C - lit.
Initial boiling point and boiling range 190 °C - lit.
Flammability (solid, gas)
No data available
Upper/lower flammability or explosive limits
Upper explosion limit: 14 %(V)
Lower explosion limit: 1,1 %(V)
Flash point 74 °C - closed cup
Autoignition temperature: 207 °C at 1.013 hPa
Decomposition temperature: No data available
pH No data available
Viscosity Viscosity, kinematic: 4,55 mm2/s at 20 °C3,82 mm2/s at 25 °C
Viscosity, dynamic: No data available
Water solubility soluble
Partition coefficient:n-octanol/water
log Pow: 0,004 at 25 °C
Vapor pressure: 0,5 hPa at 25 °C
Density: 0,951 g/cm3 at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available

Physical Properties of Dipropylene glycol monomethyl ether:
Appearance:colorless clear liquid
Assay: 98.00 to 100.00
Food Chemicals Codex Listed:No
Boiling Point: 110.00 to 111.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 12.421000 mmHg @ 25.00 °C. (est)
Flash Point:104.00 °F. TCC ( 39.90 °C. ) (est)
logP (o/w):0.287 (est)
Soluble in:
alcohol
water
water, 1e+006 mg/L @ 25 °C (est)

Physicochemical Information OF Dipropylene glycol monomethyl ether
Boiling point: 184 °C (1013 hPa)
Density: 0.95 g/cm3 (20 °C)
Explosion limit 1.1 - 14 %(V)
Flash point: 75 °C
Ignition temperature: 205 °C DIN 51794
Melting Point: -83 °C
pH value: 6 - 7 (200 g/l, H₂O, 20 °C)
Vapor pressure: 0.75 hPa (25 °C)

Toxicological Information
LD 50 oral: LD50 Rat > 5000 mg/kg
LD 50 dermal: LD50 Rabbit 9500 mg/kg
Safety Information according to GHS
RTECS: JM1575000
Storage class: 10 - 13 Other liquids and solids
WGK: WGK 1 slightly hazardous to water
Disposal: 3
Relatively unreactive organic reagents should be collected in container A.
If halogenated, they should be collected in container B. For solid residues use container C.

Storage and Shipping Information o Dipropylene glycol monomethyl ether
Storage Store below +30°C.
Specifications
Assay isomers (GC, area%): ≥ 95.0 % (a/a)
Density (d 20 °C/ 4 °C) 0.953 - 0.959
Identity (IR) passes test

Properties of Dipropylene glycol monomethyl ether
Chemical formula: C7H16O3
Molar mass: 148.202 g·mol−1
Density: 0.951 g/cm3[2]
Boiling point: 190 °C (374 °F; 463 K)
Solubility in water: Miscible[2]


Computed Properties of Dipropylene glycol monomethyl ether

Molecular Weight: 148.20
XLogP3 -0.1 Computed by XLogP3 3.0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 5
Exact Mass: 148.109944368
Monoisotopic Mass: 148.109944368
Topological Polar Surface Area: 38.7 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 75.3
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Description and Use of Dipropylene glycol monomethyl ether
Dipropylene Glycol Methyl Ether is a colorless liquid with a mild and pleasant odor.
Dipropylene glycol monomethyl ether is a solvent used in paints, pastes, dyes, resins, brake fluids and inks, and in making cosmetics.
ODOR THRESHOLD = 35 ppm
Odor thresholds vary greatly. Do not rely on odor alone to determine potentially hazardous exposures.

First aid measures for Dipropylene glycol monomethyl ether
Description of first-aid measures
General advice
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person.
Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
No data available

Firefighting measures for Dipropylene Glycol Methyl Ether
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
Use water spray to cool unopened containers.

Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid breathing vapors, mist or gas. Remove all sources of ignition.
Beware of vapors accumulating to form explosive concentrations.
Vapors can accumulate in low areas.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wetbrushing and place in container for disposal according to local regulations (see section
Keep in suitable, closed containers for disposal.

Handling and storage for Dipropylene Glycol Methyl Ether
Precautions for safe handling
Advice on safe handling
Avoid inhalation of vapor or mist.
Advice on protection against fire and explosion
Keep away from sources of ignition
No smoking.
Take measures to prevent the build up of electrostatic charge.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Conditions for safe storage, including any incompatibilities
Storage conditions
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Storage class

Stability and reactivity of Dipropylene glycol monomethyl ether
Reactivity: No data available
Chemical stability: Stable under recommended storage conditions.
Possibility of hazardous reactions:
No data available
Conditions to avoid:
Heat, flames and sparks.
Incompatible materials:
Strong oxidizing agents, Strong acids

History of Dipropylene glycol monomethyl ether
Dipropylene glycol methyl ether (DPGME) is one of the most commonly used propylene glycol ethers in industry and is discussed in a recently published NEG/NIOSH document.
DPGME is a collective term describing a mixture of structural isomers.
In the past, OSHA has determined airborne concentrations based on a method validated by NIOSH.
The method specifies collection of the vapors on activated charcoal, desorption of the charcoal with carbon disulfide, and analysis by GC using flame ionization detection.

An examination of the Backup Data Report for the NIOSH method revealed that the desorption efficiency was not constant, the desorption efficiency of the individual isomers of DPGME was not investigated, and the desorption efficiency from wet charcoal was not addressed.
The reported desorption efficiency ranged from 60.4% at 2.954 mg to 89.1% at 12.01 mg of DPGME.
In cases where the desorption efficiency is not constant, calculations to determine analyte concentrations are complicated through the use of a desorption efficiency curve.
Also, a desorption efficiency less than 75% does not meet one of the evaluation requirements used by the Organic Methods Evaluation Branch of the OSHA Salt Lake Technical Center (SLTC).
For analytes such as DPGME, which are comprised as mixtures of related compounds, quantitation is accomplished by summing the peak areas of each component and treating the summed areas as one analyte.
This is an accepted and convenient practice when using a flame ionization detector because the responses for all of the isomers of DPGME are identical.
But if the desorption efficiencies are not the same for each isomer, they must be quantitated separately with individual desorption efficiency corrections, and then the resulting amounts are summed to determine the total amount of Dipropylene glycol monomethyl ether.
This procedure is necessary for any method using charcoal collection and carbon disulfide desorption because the relative proportion of isomers in DPGME can vary by lot and manufacturer.
Because charcoal will always collect some water from sampled air, the desorption of DPGME from wet charcoal is an important consideration as evidenced by evaluations done at SLTC for other chemically similar analytes.
For those analytes, the recovery from wet charcoal is significantly lower unless a drying agent such as magnesium sulfate is used in the desorption step.

The present evaluation was accomplished using a desorption solvent consisting of 95/5 (v/v) methylene chloride/methanol, which is used for other chemically similar compounds evaluated at SLTC.
Using this desorption solvent, the desorption efficiencies of all the isomers of DPGME were found to be essentially identical at approximately 100%, thus peak summations can be done.
The desorption efficiencies are constant with concentration and are not affected by the presence of water, so a drying agent is not needed for the desorption step.

TYPICAL PRODUCT SPECIFICATIONS of Dipropylene Glycol Methyl EtherPURITY:98.5% m/m min
WATER:0.05% m/m
DENSITY @ 20C: 0.953 kg/L
COEFFICIENT OF CUBIC EXPANSION @ 20C: 10 10^-4/C
REFRACTIVE INDEX @ 20° C: 1.423
COLOR: BOILING POINT: 191 C
RELATIVE EVAPORATION RATE (NBUAC=1): 0.04
RELATIVE EVAPORATION RATE (ETHER=1): 360
ANTOINE CONSTANT A #: 6.70707 kPa, C
ANTOINE CONSTANT B #: 1633.03 kPa, C
ANTOINE CONSTANT C #: 161.693 kPa, C
TEMPERATURE LIMITS FOR ANTOINE EQUATION: +50 to +190 C
VAPOUR PRESSURE @ 20C: VAPOR PRESSURE @ 50C: 0.10 kPa
SATURATED VAPOUR CONCENTRATION @ 20C: FLASH POINT (ABEL): 79 C
AUTO IGNITION TEMP: 205 C
LOWER EXPLOSION LIMIT: 1.3% v/v
UPPER EXPLOSION LIMIT: 8.7% v/v
ELECTRICAL CONDUCTIVITY @ 20C: 10 uS/m
DIELECTRIC CONSTANT @ 20C: 10.5
FREEZING POINT: -83 C
SURFACE TENSION @ 20C: 29 mN/m
VISCOSITY @ 20C: 4.3 mPa.s
HILDEBRAND SOLUBILITY PARAMETER: 8.7 (cal/cm^3)^1/2
HYDROGEN BONDING INDEX: 0.0
FRACTIONAL POLARITY: 0.050
DILUTION RATIO: TOLUENE: 4.2
DILUTION RATIO: SBP 100/140: 0.8
HEAT OF VAPORIZATION @TBOIL: 306 kJ/kg
HEAT OF COMBUSTION (NET) @25C: 27500 kJ/kg
SPECIFIC HEAT @20C: 2.0 kJ/kg/C
THERMAL CONDUCTIVITY @ 20C: 0.11 W/m/C
MISCIBILITY @20C: SOLVENT IN WATER
MISCIBILITY @20C: WATER IN SOLVENT: complete
AZEOTRAPE WITH WATER: BOILING POINT. 99.2 C
AZEOTROPE WITH WATER: SOLVENT CONTENT: 8.0 % m/m
MOLECULAR WEIGHT: 148 g/mol
CLASS: Solvents - Glycols - Alcohols, Organic Intermediates and Compounds
FUNCTIONS: Solvents, Drilling Fluid Additives, Organic Intermediate
INDUSTRY: Industrial, Industrial Drilling, Oil and Gas Production, Drilling Fluid, Hydraulic Fracturing, Fracking, Organics, Solvents

Product Description of Dipropylene glycol monomethyl ether
Catalogue Number: D495808
Chemical NameDipropylene Glycol Monomethyl Ether (Mixture of Isomers)
CAS Number: 34590-94-8
Molecular Formula: C₇H₁₆O₃
Appearance: Colourless Oil
Molecular Weight: 148.2
Storage: 4°C
SolubilityChloroform (Slightly), Methanol (Slightly)
Stability: Not determined
Applications of Dipropylene glycol monomethyl ether
Dipropylene Glycol Monomethyl Ether is used in preparation of special cleaning agent for pot bottom black dirt.

Technical Data of Dipropylene glycol monomethyl ether
CAS No: [88917-22-0]
Product Code: NDA91722
Chemical Formula: CH3CO2C3H6OC3H6OCH3
Molecular Weight: 190.24 g/mol
Smiles: CC(COC)OCC(C)OC(=O)C
Flash Point: 200 °C

Toxicological information of Dipropylene glycol monomethyl ether
Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - male and female - > 5.000 mg/kg
LC50 Inhalation - Rat - 4 h - 55 - 60 mg/l - vapor
LD50 Dermal - Rabbit - male - 9.510 mg/kg
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation
Serious eye damage/eye irritation
Eyes - In vitro study
Result: No eye irritation - 1 h

Respiratory or skin sensitization
in vivo assay - Human
Result: negative
Remarks: (ECHA)

FIRST AID of Dipropylene glycol monomethyl ether
Eye Contact
If Immediately flush with large amounts of water for at least 15 minutes, lifting upper and lower lids.
Remove contact lenses, if worn, while rinsing.
Skin Contact
If Remove contaminated clothing and wash contaminated skin with soap and water.
Inhalation
ıf Remove the person from exposure.
ıf Begin rescue breathing (using universal precautions) if breathing has stopped and CPR if heart action has stopped.
If Transfer promptly to a medical facility.

Description OF Dipropylene glycol monomethyl ether
Catalogue Number: 818533
Product Information
CAS number: 34590-94-8
EC number: 252-104-2
Hill Formula: C₇H₁₆O₃
Chemical formula: (CH₃O)C₃H₆OC₃H₆(OH)
Molar Mass: 148.2 g/mol
HS Code: 2909 49 80
Quality Level: MQ200

PHYSICAL & CHEMICAL INFORMATION of Dipropylene glycol methyl ether
Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR.

Physical dangers
No data.

Chemical dangers
Reacts with strong acids and strong oxidants.

Formula: C9H18O4
Molecular mass: 190.2
Boiling point: 209°C
Melting point: -25.5°C
Density: 0.98 g/cm³
Solubility in water, g/100ml: 16 (good)
Vapour pressure, Pa at 25°C: 17
Relative vapour density (air = 1): 6.56
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 86°C
Auto-ignition temperature: 285°C
Explosive limits, vol% in air: 1.21-5.35
Octanol/water partition coefficient as log Pow: 0.803
Viscosity: 1.7 mm²/s at 25°C

EXPOSURE & HEALTH EFFECTS
Routes of exposure

Effects of short-term exposure
If swallowed the substance may cause vomiting and could result in aspiration pneumonitis.

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.


Physical Properties of Dipropylene glycol methyl ether
Chemical Formula: C7H16O3
Flash Point: 166°F
Lower Explosive Limit (LEL): Data not available.
Upper Explosive Limit (UEL): Data not available.
Autoignition Temperature: data unavailable
Melting Point: -117°F
Vapor Pressure: 0.5 mmHg
Vapor Density (Relative to Air): 5.11
Specific Gravity: 0.951 at 68°F
Boiling Point: 363.2°F at 760 mmHg
Molecular Weight: 148.2
Water Solubility: Miscible
Ionization Energy/Potential: data unavailable
IDLH: 600 ppm

Physical Properties of Dipropylene glycol methyl ether
Physical description:Colorless liquid with a mild, ether-like odor.
Boiling point: 408°F
Molecular weight: 148.2
Freezing point/melting point: -112°F
Vapor pressure: 0.5 mmHg
Flash point: 166°F
Vapor density: 5.11
Specific gravity: 0.95
Ionization potential
Lower explosive limit (LEL): 1.1% at 392°F
Upper explosive limit (UEL): 3%
NFPA health rating: 2
NFPA fire rating: 2
NFPA reactivity rating 0

Properties
Glycol Ether DPM is a colorless, liquid with low toxicity having a mild, pleasant odor.
It is completely water soluble, miscible with a number of organic solvents and has good solvency for a number of substances.
Chemical Family: Propylene Glycol Ether
Other Names DPG Methyl Ether
Dipropylene Glycol Methyl Ether
Dipropylene Glycol Mono Methyl Ether
Chemical Formula: C7H16O3
Appearance: Clear
For the most current product specification, please call 1-888-777-0232 or your local sales contact.
Density (pounds per gallon at 25°C) 7.9
Distillation @ 760mm Hg
IBP, min 180°C
DP, max 195°C
Evaporation Rate (BuAc = 100): 2
Flash Point (Tag Closed Cup) C(°F): 75(176)
Solubility by weight in water at 20°C
Solubility Parameter (Total Hansen): 10.0
Specific Gravity @25/25°C 0.949-0.960
Surface Tension (Dynes/cm) @ 25°C (77°F): 28
Refractive Index @ 25° (77°F): 1.422
Viscosity (centistokes) @ 25° (77°):3.6
Vapor Pressure @ 25°C (mm Hg): 0.2

Applications Coatings:
Glycol Ether DPM provides good solvency for a wide variety of resins includingacrylic, epoxies, alkyds, polyesters, nitrocellulose and polyurethanes.
Glycol Ether DPM has a relatively low vapor pressure (volatility) and evaporates at a slow rate.
Key properties for coating applications include complete water miscibility and good coupling ability.
Cleaners: Surface tension reduction and slow evaporation are some of the benefits of using
Glycol Ether DPM in cleaning formulations.

Dipropylene glycol methyl ether has a low odor and slow evaporation rate.
Dipropylene glycol methyl ether is a good choice for wax strippers and floor
cleaners which are spread over a large area. When used in an enclosed area, a floor cleaner containing a fast-evaporating solvent might produce an undesirable amount of solvent vapor.
Glycol Ether DPM provides good solvency for polar and non-polar materials.
Other Applications: The properties listed in the previous section also support the use of Glycol Ether DPM in agricultural, cosmetic, electronic, ink, textile and adhesive products.

Storage of Dipropylene glycol methyl ether
Safety and Handling
General industry practice is to store Glycol Ether DPM in carbon steel vessels.
Avoid contact with air when storing for long periods of time.
Store only in tightly closed, properly vented containers away from heat, sparks, open flame or strong oxidizing agents.
Use only non-sparking tools. Ground containers before beginning transfer.
Electrical equipment should conform to national electric code.
Handle empty containers carefully. Combustible residue remains after emptying.
Store in properly lined steel or stainless steel to avoid slight discoloration from mild steel.
Glycol ethers should never be stored or handled in copper or copper alloys.
This product may absorb water if exposed to air.

Typical Physical Properties of Dipropylene glycol methyl ether
Molecular Weight: 190.2 g/mol
Empirical Formula: C9H18O4
Appearance: Colorless
Freezing Point: -25°C (-13°F)
Flash Point: Closed Cup 86°C (187°F)
Boiling Point @ 760mmHg 208.9°C
(408°F)
Autoignition Temperature: 285°C (545°F)
Density @ 20°C 0.979 kg/l
8.17 lb/gal
Vapor Pressure @ 20°C: 0.08 mmHg
Evaporation Rate (nBuAc = 1) 0.015
Solubility @ 20°C
(in Water)
(Water in)
16 wt%
3.5 wt%
Refractive Index @ 20°C 1.417
Viscosity @ 25°C 1.7 cP
Surface Tension @ 25°C 27.3 dynes/cm
Lower Flammability in Air 1.21% v/v
Upper Flammability in Air 5.35% v/v
Specific Heat @ 25°C 1.94 J/g/°C
Heat of Vaporization @ normal
boiling point
241 J/g
Heat of Combustion @ 25°C 25.4 kJ/g

Health and safety information of Dipropylene glycol methyl ether
Under current U.S. OSHA's Hazardous Communication program DPMAc is classified as a combustible liquid.
Keep the material away from heat sources, hot surfaces, open flames, and sparks.
Use only in a wellventilated area.
Observe good industrial hygiene practices and use appropriate Personal Protective Equipment.
For full safety information please refer to the Safety

Storage and Handling of Dipropylene glycol methyl ether
General industry practice is to store DPMAc in carbon steel vessels.
Storage in properly lined steel or
stainless steel to avoid slight discoloration from carbon steel is recommended.
Product stored or delivered in unlined carbon steel vessels must be filtered due to technically unavoidable particles.
DPMAc should be stored under a nitrogen blanket when available.
Avoid contact with air when storing for long periods of time.
This product may absorb water if exposed to air.
DPMAc should be stored only in tightly closed, properly vented containers away from heat, sparks, open flame, or strong oxidizing agents.
Use only nonsparking tools. Containers should be grounded before beginning transfer.
Electrical equipment should conform to national electric code.
Handle empty containers carefully.
Flammable combustible residue remains after emptying.


Dipropylene glycol methyl ether
Alternative Name: DPGME
CAS Number: 34590-94-8
Formula: C7-H16-O3
Major Category
Category: Glycol Ethers (P Series)
Description: Colorless liquid with a mild, ether-like odor.
Sources/Uses
Used in hydraulic fluids and as a solvent.

Typical Properties OF Dipropylene glycol methyl ether
Purity %m/m DIN 55689: min. 98.5
Water %m/m ASTM D1364 0.05
Density @20°C kg/L ASTM D4052 0.953
Cubic Expansion Coefficient @20°C (10^‐4)/°C Calculated 10
Refractive Index @20°C : ASTM D1218 1.453
Color Pt‐Co ASTM D1209 <5
Boiling point °C ‐ 191
Relative Evaporation Rate (nBuAc=1): ASTM D3539 0.04
Relative Evaporation Rate (Ether=1) : DIN 53170 360
Antoine Constant A # kPa, °C: 6.70707
Antoine Constant B # kPa °C: 1633.03
Antoine Constant C # kPa °C: 161.693
Antoine Constants: Temperature range °C ‐ +50 to +190
Vapor Pressure @20°C kPa Calculated <0.01
Vapor Pressure @50°C kPa Calculated 0.10
Saturated Vapor Concentration @20°C g/m3 Calculated <0.5
Flash Point °C ASTM D93: 79
Auto Ignition Temperature °C ASTM E659 205
Explosion Limit: Lower %v/v: 1.3
Explosion Limit: Upper %v/v: 8.7
Electrical Conductivity @20°C μS/m ASTM D4308 10
Dielectric Constant @20°C: 10.5
Freezing Point °C: ‐83
Surface Tension @20°C mN/m: 29
Viscosity @20°C mPa.s ASTM D445 4.3
Hildebrand Solubility Parameter (cal/cm³)^½ ‐ 8.7
Hydrogen Bonding Index: 0.0
Fractional Polarity : 0.050
Dilution Ratio: Toluene : ASTM D1720 4.2
Dilution Ratio: SBP 100/140 : ASTM D1720 0.8
Heat of Vaporization @Tboil kJ/kg : 306
Heat of Combustion (Net) @25°C kJ/kg : 27500
Specific Heat @20°C kJ/kg/°C ‐ 2.0

Exposure Controls/Personal Protection
Airborne Exposure Limits:
Dipropylene glycol monomethyl ether:
OSHA Permissible Exposure Limit (PEL):
100 ppm(TWA) skin
ACGIH Threshold Limit Value (TLV):
100 ppm (TWA), 150 ppm (STEL) skin
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne
Exposure Limits.
Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
If the exposure limit is exceeded and engineering controls are not feasible, a full facepiece respirator with organic vapor cartridge may be worn up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest.
For emergencies or instances where the exposure levels are not known, use a full‐facepiece positive‐pressure, air‐supplied respirator.
WARNING: Air purifying respirators do not protect workers in oxygen‐deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible.
Maintain eye wash fountain and quick‐drench facilities in work area.

Specifications of Dipropylene glycol methyl ether
Density 0.9500g/mL
Melting Point -80.0°C
Boiling Point 180.0°C
Flash Point 75°C
Assay Percent Range 98.5% min. sum of isomers (GC)
Linear Formula CH3O(CH2)3O(CH2)3OH
Packaging Plastic drum
Merck Index 15, 3384
Quantity 5L
Solubility Information Solubility in water: soluble. Other solubilities: miscible with benzene

First aid measures
General notes
Take off contaminated clothing.
Following inhalation
Provide fresh air.
In all cases of doubt, or when symptoms persist, seek medical advice.
Following skin contact
Rinse skin with water/shower.
In all cases of doubt, or when symptoms persist, seek medical advice.
Following eye contact
Rinse cautiously with water for several minutes.
In all cases of doubt, or when symptoms persist, seek medical advice.
Following ingestion
Rinse mouth.
Call a doctor if you feel unwell.
Most important symptoms and effects, both acute and delayed
Headache, Vertigo, Irritant effects
Indication of any immediate medical attention and special treatment needed


Application: Cleaning agents, agrochemistry.

Health safety: May cause skin irritation and infection.
May be harmful to air passages and cause headache and vertigo.
May have negative influence on fertility and be harmful for children in the wombs

APPLICATION:
Water-based Coatings
Solvent-based Coatings
household and industrial cleaners, grease and paint removers, metal
cleaners, and hard surface cleaners.
Dyeing Fabrics
Personal Care & Fragrance
Agro-chemicals herbicide
Printing Chemicals and Inks
Oilfield Chemicals
Floor polishes and finishes

USES FOR Dipropylene glycol methyl ether
Coupling agent (often in blends) for water-based dilutable coatings.
Fragrance carrier for reed diffusers
Active solvent for solvent-based coatings.
Coupling agent and solvent in household and industrial cleaners, grease and paint removers, metal cleaners, and hard surface cleaners.
Tail solvent for solvent-based gravure and flexographic printing inks.
Primary solvent in solvent-based silk screen printing inks.
Coupling agent in solvent blends for water-based gravure, flexographic, and silk screen printing inks.
Coupling agent and solvent for vat dyeing fabrics.
Stabilizer for agricultural herbicides.
Coalescent for floor polishes and finishes

Properties of Dipropylene glycol methyl ether:
Formula: CH3O[CH2CH(CH­3)O]2H
CAS No: 34590-94-8
Molar mass: 148.2 g mol?1
Density: 0.951 g/cm, liquid
Boiling Point: 190 C
Viscosity: 3.7 cP at 25 C

Dipropylene glycol monomethyl ether Properties
Melting point: -80°C
Boiling point: 90-91 °C12 mm Hg(lit.)
Density: 0.954 g/mL at 20 °C(lit.)
vapor pressure: 0.4 mm Hg ( 25 °C)
refractive index: n20/D 1.422
Flash point: 166 °F
storage temp.: Store below +30°C.
Water Solubility: Completely miscible in water
form: Colorless liquid
color: Colorless to Almost colorless
PH: 6-7 (200g/l, H2O, 20℃)
explosive limit 1.1-14%(V)
Viscosity: 4.55mm2/s
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.

Transportation data
State: liquid
Temperature (°C): ambient
Pressure (Pa): ambient
Reactivity data
Abilities: Miscible in water.

Application in coating: PM, low toxic and strong soluble, is widely used as solvent and coupling agent of ink, paint coating and water-based paint.
Dipropylene glycol methyl ether is suitable for benzene propylene emulsion, propylene alkene acid emulsion and its emulsion paint, which are characterized by reducing the coating temperature, speeding its cohesion and keeping the coating in a good condition.
Application in pesticide: PM is mainly used as intermediate of metolachlor for weedicide, and as suspension agent of pesticide emulsion.
Other applications: PM can be used in anti-freezer of fuel, cleanser, extractor, and ore-dressing agent for non-ferrous metals.
In addition, it can be used as material of organic synthesis, dyestuff of dyeing and textile, and solvent of spinning oil.

Dipropylene glycol methyl ether is used as solvent for PVC stabilizer, nitrocellulose, ethyl cellulose, polyvinyl acetate, solvent for paint and dyestuff, and an ingredient of brake fluid.
It can be used as solvent of printing ink, enamel paint, cutting fluid and operating oil; as coupling agent of water-based paint (usually used by mixing up); as active solvent of water-based paint; as solvent and coupling agent of household and industrial cleanser, remover for grease and paint, cleanser for metal and hard surface; as base solvent and coupling agent of solvent-type silk-screen printing ink; as solvent and coupling agent of vat dye textile; as coupling agent and skin-care agent in cosmetic formula; as stabilizer of pesticide and coagulating?agent of floor brightener.

Uses
Dipropylene glycol monomethyl ether is a very useful industrial and commercial chemical. One of its main commercial uses is as a solvent for paints, varnishes, inks, strippers, and degreasers.
Dipropylene glycol methyl ether is also utilised as a coalescing agent for water-based paints and inks where it promotes polymer fusing during the drying process.
Dipropylene glycol methyl ether is also a component of wood and coil coatings, as well as coatings used in the automotive industry, industrial maintainence, and metal finishing.
Dipropylene glycol methyl ether is also a component of hydraulic fluids and industrial degreasers and is a chemical additive in the oil production and drilling industry.

Dipropylene glycol methyl ether is a useful chemical building block in the manufacture of other products as it reacts with acids to form esters, oxidising agents to form aldehydes or carboxylic acids, alkali metals to form alcoholates, and aldehydes to form acetals.
Dipropylene glycol methyl ether is this flexibility that supports the use of DPM across a range of industries and DPM is, therefore, a component of many household items that people use every day.
Dipropylene glycol methyl ether is found in ceiling and wall paints, and in many common cleaners including glass and surface cleaners, paint-brush cleaners, all-purpose cleaners, carpet cleaners, and disinfectant cleaners.
Dipropylene glycol methyl ether is also found in cosmetics where it provides emoillient properties and product stabilisation.
Dipropylene glycol methyl ether is also found in floor polish and aluminium polish, leather and textile dyes, rust removers, and pescticides where it acts as a stabiliser.

TYPICAL SPECIFICATIONS
CLASS: Glycol Ethers
MOLECULAR WEIGHT: 90.12
APPEARANCE: Colorless liquid
DENSITY: 0.916 g/cm3
REFRACTIVE INDEX:1.403
ASSAY: ≥99.5 %
WATER CONTENT: ≤0.001 %
BOILING POINT: 118 - 119 °C
MELTING POINT: -97 °C

Usage areas of Dipropylene glycol methyl ether
Dipropylene glycol is used as a heat transfer fluid for both low and high temperature applications.
Dipropylene glycol methyl ether is used as a high-temperature reaction medium in the synthesis of some drugs, and also as antifreeze.
Dipropylene glycol has germicidal properties and can be used as an air purifying agent.
Dipropylene glycol methyl ether is used as a solvent in many sectors.
Dipropylene glycol methyl ether finds application in the production of mainly industrial intermediates, unsaturated polyester resins, plasticizers, alkyd resins, cosmetics and urethane polyols, and is included as an additive in the formulations of antifoaming agents, industrial soaps and functional fluids.
Dipropylene glycol methyl ether is a solvent and is used as a moisturizing agent, acting as a diluent and/or carrier in fragrance and deodorant applications, and is involved in diluting fragrance oils.
Dipropylene glycol methyl ether acts as an additive in many cosmetic product formulations such as hair care and bath products, deodorants, shaving and skin care products.
Propylene glycol, dipropylene glycol and tripropylene glycol; solvent, softener, emulsion stabilizer or viscosity modifier in fragrance, cosmetics and personal care products; humectant due to its hygroscopic nature and ability to retain water.
Dipropylene glycol methyl ether is used as a preservative against many bacterial and fungal species.
In skin care products such as creams, moisturizers, cleansers, lotions, sun care products; in deodorants; in hair care products such as shampoo, coloring products; in shaving products such as creams, foams, gels and aftershave lotions; in bath and shower products; in perfumes and colognes; in baby care products.
Dipropylene glycol methyl ether is included in cosmetic products such as eyeliner and lip paint, and in formulations of oral care products such as mouthwash and toothpaste.

Synthesis Method of Dipropylene glycol methyl ether
Dipropylene glycol methyl ether can be synthesized by the reaction of propylene oxide with methanol in the presence of an acid catalyst.
The reaction is typically carried out at temperatures between 80 and 100 °C, and the reaction is usually complete within two hours.
The reaction produces a mixture of mono-, di-, and tripropylene glycol methyl ethers.
The mono- and di-propylene glycol methyl ethers can then be separated from the tripropylene glycol methyl ethers by distillation.

Synonyms of Dipropylene glycolmethyl ether
2-(2-methoxypropoxy)propan-1-ol
Dipropylene glycol methyl ether
13588-28-
2-(2-METHOXYPROPOXY)-1-PROPANOL
1-Propanol, 2-(2-methoxypropoxy)-
2-(2-methoxypropoxy)propanol
12002-25-4
Glycol Ether DPM
SCHEMBL16073
Glycol Ether DPM Reagent Grade
dipropyleneglycol monomethyl ether
DTXSID80864425
MFCD19707082
AKOS037648698
NCGC00090688-04
BS-15252
CS-0154037
FT-0625302
D81108
J-019668
J-520393
Q2954819
Ucar solvent 2LM
Dowanol DPM
Dowanol-50B
DPGM PPG-2 methyl ether
Bis(2-(methoxypropyl) ether
Dipropylene glycol monomethyl ether
Dipropylene glycol methyl ether
(2-Methoxymethylet­hoxy)propanol
HSDB 2511, Propanol
(2-methoxymethylet­hoxy)-
Dipropylene glycol
monomethyl ether
EINECS 252-104-2
1-Propanol
2-(2-methoxypropoxy)-
CID25485, 1-(2-Methoxyisopropoxy)-2-propanol
1,4-Dimethyl-3,6-dioxa-1-heptanol
DIPROPYLENE GLYCOL METHYL ETHER
Dipropylene glycol methyl ether IUPAC Name 2-(2-methoxypropoxy)propan-1-ol Dipropylene glycol methyl ether InChI InChI=1S/C7H16O3/c1-6(4-8)10-5-7(2)9-3/h6-8H,4-5H2,1-3H3 Dipropylene glycol methyl ether InChI Key CUDYYMUUJHLCGZ-UHFFFAOYSA-N Dipropylene glycol methyl ether Canonical SMILES CC(CO)OCC(C)OC Dipropylene glycol methyl ether Molecular Formula C7H16O3 Dipropylene glycol methyl ether CAS 34590-94-8 Dipropylene glycol methyl ether ICSC Number 0884 Dipropylene glycol methyl ether DSSTox Substance ID DTXSID80864425 Dipropylene glycol methyl ether EC Number 252-104-2 Dipropylene glycol methyl ether Physical Description Dipropylene glycol methyl ether is a colorless liquid with a weak odor . Dipropylene glycol methyl ether Boiling Point 363.2 °F at 760 mm Hg Dipropylene glycol methyl ether Melting Point -117 °F Dipropylene glycol methyl ether Flash Point 166 °F Dipropylene glycol methyl ether Solubility Miscible Dipropylene glycol methyl ether Density 0.951 at 68 °F Dipropylene glycol methyl ether Vapor Density 5.11 Dipropylene glycol methyl ether Vapor Pressure 0.5 mm Hg Dipropylene glycol methyl ether Autoignition Temperature 270 °C Dipropylene glycol methyl ether Molecular Weight 148.2 g/mol Dipropylene glycol methyl ether XLogP3 -0.1 Dipropylene glycol methyl ether Hydrogen Bond Donor Count 1 Dipropylene glycol methyl ether Hydrogen Bond Acceptor Count 3 Dipropylene glycol methyl ether Rotatable Bond Count 5 Dipropylene glycol methyl ether Exact Mass 148.109944 g/mol Dipropylene glycol methyl ether Monoisotopic Mass 148.109944 g/mol Dipropylene glycol methyl ether Topological Polar Surface Area 38.7 Ų Dipropylene glycol methyl ether Heavy Atom Count 10 Dipropylene glycol methyl ether Formal Charge 0 Dipropylene glycol methyl ether Complexity 75.3 Dipropylene glycol methyl ether Isotope Atom Count 0 Dipropylene glycol methyl ether Defined Atom Stereocenter Count 0 Dipropylene glycol methyl ether Undefined Atom Stereocenter Count 2 Dipropylene glycol methyl ether Defined Bond Stereocenter Count 0 Dipropylene glycol methyl ether Undefined Bond Stereocenter Count 0 Dipropylene glycol methyl ether Covalently-Bonded Unit Count 1 Dipropylene glycol methyl ether Compound Is Canonicalized Yes Chemical: Dipropylene glycol methyl ether .Dipropylene glycol methyl ether is a colorless liquid with a weak odor .Dipropylene glycol methyl ether is an organic solvent with a variety of industrial and commercial uses.It finds use as a less volatile alternative to propylene glycol methyl ether and other glycol ethers. The commercial product is typically a mixture of four isomers.Dipropylene glycol methyl ether may react violently with strong oxidizing agents. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. May initiate the polymerization of isocyanates and epoxides.Dipropylene glycol methyl ether (mixture of isomeres) for synthesis. CAS 34590-94-8, chemical formula (CH₃O)C₃H₆OC₃H₆(OH).Dipropylene glycol methyl ether (DPGME) is one of the most commonly used propylene glycol ethers in industry and is discussed in a recently published NEG/NIOSH document.Dipropylene glycol methyl ether is a collective term describing a mixture of structural isomers. In the past, OSHA has determined airborne concentrations based on a method validated by NIOSH.An examination of the Backup Data Report for the NIOSH method (Ref. 5.3) revealed that the desorption efficiency was not constant, the desorption efficiency of the individual isomers of Dipropylene glycol methyl ether was not investigated, and the desorption efficiency from wet charcoal was not addressed.The reported desorption efficiency ranged from 60.4% at 2.954 mg to 89.1% at 12.01 mg of Dipropylene glycol methyl ether.For analytes such as Dipropylene glycol methyl ether, which are comprised as mixtures of related compounds, quantitation is accomplished by summing the peak areas of each component and treating the summed areas as one analyte.This is an accepted and convenient practice when using a flame ionization detector because the responses for all of the isomers of Dipropylene glycol methyl ether are identical.But if the desorption efficiencies are not the same for each isomer, they must be quantitated separately with individual desorption efficiency corrections, and then the resulting amounts are summed to determine the total amount of Dipropylene glycol methyl ether. This procedure is necessary for any method using charcoal collection and carbon disulfide desorption because the relative proportion of isomers in Dipropylene glycol methyl ether can vary by lot and manufacturer.Using this desorption solvent, the desorption efficiencies of all the isomers of Dipropylene glycol methyl ether were found to be essentially identical at approximately 100%, thus peak summations can be done.The desorption efficiencies from dry charcoal ranged from 76-93% for the isomers at a loading of 6.0 mg of Dipropylene glycol methyl ether.In the review presented in the previously mentioned NEG/NIOSH document, it was concluded that Dipropylene glycol methyl ether seems to lack reproductive toxicity, unlike some other chemically similar compounds.At very high air concentrations, Dipropylene glycol methyl ether causes narcosis in animals. It is expected that severe exposure would produce similar effects in humans, but high concentrations are disagreeable and not tolerated.Dipropylene glycol methyl ether at 300 ppm caused eye and nasal irritation to humans.ACGIH has established a TLV-TWA of 100 ppm and a TLV-STEL of 150 ppm for Dipropylene glycol methyl ether.Dipropylene glycol methyl ether is used as a solvent for paints, lacquers, resins, dyes, oil/greases, cleaners and cellulose and as a heat-transfer agent. It is frequently used as a substitute for the more toxic DEGME (diethylene glycol methyl ether).Dipropylene glycol methyl ether is a mixture of structural isomers. Also, each isomer has two asymmetrical carbon atoms, thus configurational isomers can exist. The numbers in parentheses are approximate percentages by weight of each isomer found in the Dipropylene glycol methyl ether used in this evaluation. The abbreviations in the brackets are used in chromatograms in this method.Dipropylene glycol methyl ether is a glycol ether based on propylene oxide and methanol. It is a speciality solvent having a bi-functional nature (ether-alcohol). It is a clear liquid with an ether-like odour. Dipropylene glycol methyl ether is not flammable, but a combustible liquid with a flashpoint of 1670 F/750C. Typically, the concentration of Dipropylene glycol methyl ether is 99%; 2-Methoxypropanol-1 can be present as an impurity at max. 0.1%. Dipropylene glycol methyl ether is not classified as a carcinogen or mutagen; it is not expected to cause cancer in humans, nor does it impair fertility or damage the developing fetus. Dipropylene glycol methyl ether is transported by tank truck, rail car and vessel, primarily in bulk quantities, but also as a packed product. It is not classified as hazardous for transport under transport regulations.Dipropylene glycol methyl ether at any exposure concentration in either male or female rats or rabbits. The highest concentration tested (200 ppm) was approximately 40% of a saturated Dipropylene glycol methyl ether atmosphere, Based on the low vapor pressure of Dipropylene glycol methyl ether, and results in this 13-week study, Dipropylene glycol methyl ether appears to have a low subchronic vapor inhalation toxicity hazard.Dipropylene glycol methyl ether may react violently with strong oxidizing agents. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. May initiate the polymerization of isocyanates and epoxides.The invention discloses a method for preparing Dipropylene glycol methyl ether. The method for preparing the Dipropylene glycol methyl ether is characterized by comprising the following steps of taking tower bottoms left after propylene glycol methyl ether is extracted as raw materials, performing a ring-opening addition reaction on the raw materials and epoxypropane in the presence of a strongly basic catalyst, recovering excessive 2-methoxy-1-propyl alcohol in the synthetic products by virtue of rectification and then separating to obtain the product Dipropylene glycol methyl ether. The method for preparing the Dipropylene glycol methyl ether has the advantages that as15-25% of Dipropylene glycol methyl ether continues reacting with the epoxypropane to generate tripropylene glycol methyl ether which is higher in boiling point in the process of synthesizing the Dipropylene glycol methyl ether by reacting the tower bottoms and the epoxypropane, enough output of the tripropylene glycol methyl ether is guaranteed by use of the synthesis method, and the tripropylene glycol methyl ether is capable of continuing dissolving catalysts such as sodium methylate and sodium hydroxide so that the sodium methylate can be prevented from being decomposed to generate methanol as being heated under the circumstance of a relatively high concentration, and therefore, the potential hazard that the methanol is possible to be in an explosion range after being mixed with air and explodes under high heat can be avoided.The present invention relates to a kind of method of preparing Dipropylene glycol methyl ether, belong to organic solvent preparation field.1. a method of preparing Dipropylene glycol methyl ether, it is characterized in that: the tower bottoms having extracted after propylene glycol monomethyl ether of take is raw material, under the effect of strong alkali catalyst, carry out opening with propylene oxide, by rectifying, reclaim out after 2-methoxy-1-propanol excessive in synthetic product, then separation obtains product Dipropylene glycol methyl ether.CALL FOR MEDICAL AID. LIQUID: Irritating to skin and eyes. Harmful if swallowed. Remove contaminated clothing and shoes. Flush affected areas with plenty of water. IF IN EYES, hold eyelids open and flush with plenty of water. May be harmful by inhalation, ingestion, or skin absorption. May cause irritation.Eye: If this chemical contacts the eyes, immediately wash the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. Contact lenses should not be worn when working with this chemical. Skin: If this chemical contacts the skin, promptly wash the contaminated skin with water. If this chemical penetrates the clothing, promptly remove the clothing and wash the skin with water. If irritation persists after washing, get medical attention. Breathing: If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform mouth-to-mouth resuscitation. Keep the affected person warm and at rest. Get medical attention as soon as possible. Swallow: If this chemical has been swallowed, get medical attention immediately.Eye:Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.Skin:Water wash promptly - If this chemical contacts the skin, promptly wash the contaminated skin with water. If this chemical penetrates the clothing, promptly remove the clothing and wash the skin with water. If irritation persists after washing, get medical attention.Breathing:Respiratory support.Swallow:Medical attention immediately - If this chemical has been swallowed, get medical attention immediately.Stop discharge if possible. Call fire department. Avoid contact with liquid. Isolate and remove discharged material. Notify local health and pollution control agencies. Evacuate areas. Should be removed. Chemical and physical treatment. Effect of low concentrations on aquatic life is unknown. May be dangerous if it enters water intakes. Notify local health and wildlife officials. Notify operators of nearby water intakes. Skin: No recommendation is made specifying the need for personal protective equipment for the body. Eyes: No recommendation is made specifying the need for eye protection. Wash skin: No recommendation is made specifying the need for washing the substance from the skin (either immediately or at the end of the work shift). Remove: No recommendation is made specifying the need for removing clothing that becomes wet or contaminated. Change: No recommendation is made specifying the need for the worker to change clothing after the work shift.Oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick, 1979 p.151-154, 164]. Miscible with water.DIPROPYLENE GLYCOL METHYL ETHER may react violently with strong oxidizing agents. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. May initiate the polymerization of isocyanates and epoxides.inhalation, skin absorption, ingestion, skin and/or eye contactirritation eyes, nose, throat; lassitude (weakness, exhaustion), dizziness, headache.Dipropylene glycol methyl ether (DPGME) is one of the most commonly used propylene glycol ethers in industry and is discussed in a recently published NEG/NIOSH document. (Ref. 5.1) DPGME is a collective term describing a mixture of structural isomers. In the past, OSHA has determined airborne concentrations based on a method validated by NIOSH (Ref. 5.2). The method specifies collection of the vapors on activated charcoal, desorption of the charcoal with carbon disulfide, and analysis by GC using flame ionization detection.An examination of the Backup Data Report for the NIOSH method (Ref. 5.3) revealed that the desorption efficiency was not constant, the desorption efficiency of the individual isomers of DPGME was not investigated, and the desorption efficiency from wet charcoal was not addressed.The reported desorption efficiency ranged from 60.4% at 2.954 mg to 89.1% at 12.01 mg of DPGME. In cases where the desorption efficiency is not constant, calculations to determine analyte concentrations are complicated through the use of a desorption efficiency curve. Also, a desorption efficiency less than 75% does not meet one of the evaluation requirements used by the Organic Methods Evaluation Branch of the OSHA Salt Lake Technical Center (SLTC).For analytes such as DPGME, which are comprised as mixtures of related compounds, quantitation is accomplished by summing the peak areas of each component and treating the summed areas as one analyte. This is an accepted and convenient practice when using a flame ionization detector because the responses for all of the isomers of DPGME are identical. But if the desorption efficiencies are not the same for each isomer, they must be quantitated separately with individual desorption efficiency corrections, and then the resulting amounts are summed to determine the total amount of DPGME. This procedure is necessary for any method using charcoal collection and carbon disulfide desorption because the relative proportion of isomers in DPGME can vary by lot and manufacturer.Because charcoal will always collect some water from sampled air, the desorption of DPGME from wet charcoal is an important consideration as evidenced by evaluations done at SLTC for other chemically similar analytes. (Refs. 5.4-5.5) For those analytes, the recovery from wet charcoal is significantly lower unless a drying agent such as magnesium sulfate is used in the desorption step.The present evaluation was accomplished using a desorption solvent consisting of 95/5 (v/v) methylene chloride/methanol, which is used for other chemically similar compounds evaluated at SLTC. (Refs. 5.4-5.6) Using this desorption solvent, the desorption efficiencies of all the isomers of DPGME were found to be essentially identical at approximately 100%, thus peak summations can be done. The desorption efficiencies are constant with concentration and are not affected by the presence of water, so a drying agent is not needed for the desorption step.The use of 99/1 (v/v) carbon disulfide/N,N-dimethylformamide (CS2/DMF) was investigated as an alternative desorption solvent because it is used for the analysis of many solvent vapors collected on charcoal and analyzed at SLTC. The desorption efficiencies from dry charcoal ranged from 76-93% for the isomers at a loading of 6.0 mg of DPGME. When tests were repeated with charcoal that previously had 10 L of 80% relative humidity air drawn through it, the desorption efficiencies ranged from 52-86%. Reanalysis of these samples after addition of 125 mg of magnesium sulfate brought the efficiencies nearly up to that from dry charcoal. Thus this solvent system would be acceptable if each of the isomers was quantitated separately with its appropriate desorption efficiency correction, but it is clearly not the desorption solvent of choice.In the review presented in the previously mentioned NEG/NIOSH document, it was concluded that DPGME seems to lack reproductive toxicity, unlike some other chemically similar compounds. At very high air concentrations, DPGME causes narcosis in animals. It is expected that severe exposure would produce similar effects in humans, but high concentrations are disagreeable and not tolerated. Also, concentrations over 200 ppm (40% saturated atmosphere) are difficult to attain, which suggests these high concentrations would not likely be found in workplace air. DPGME at 300 ppm caused eye and nasal irritation to humans. There was no evidence of skin irritation from prolonged or repeated contact with the pure liquid. High vapor concentrations or direct contact of the eyes with the liquid causes transient irritation. (Ref. 5.7) The OSHA PEL-TWA is 100 ppm. (Ref. 5.8) ACGIH has established a TLV-TWA of 100 ppm and a TLV-STEL of 150 ppm for DPGME. (Ref. 5.9)DPGME is used as a solvent for paints, lacquers, resins, dyes, oil/greases, cleaners and cellulose and as a heat-transfer agent. It is frequently used as a substitute for the more toxic DEGME (diethylene glycol methyl ether).DPGME is a mixture of structural isomers. Also, each isomer has two asymmetrical carbon atoms, thus configurational isomers can exist. The numbers in parentheses are approximate percentages by weight of each isomer found in the DPGME used in this evaluation. The abbreviations in the brackets are used in chromatograms in this method.The analyte air concentrations throughout this method are based on the recommended sampling and analytical parameters. Air concentrations listed in ppm and ppb are referenced to 25°C and 101.3 kPa (760 mmHg).The DPGME concentration for samples is obtained from the appropriate calibration curve in terms of micrograms of analyte per sample, uncorrected for desorption efficiency. The air concentration is calculated using the following formulae. The back (50-mg) section is analyzed primarily to determine if there was any breakthrough from the front (100-mg) section during sampling. If a significant amount of analyte is found on the back section (e.g., greater than 25% of the amount found on the front section), this fact should be reported with sample results. If any analyte is found on the back section, it is added to the amount found on the front section. This total amount is then corrected by subtracting the total amount (if any) found on the blank.Dipropylene Glycol Methyl Ether (DPGME) is a mixture of four isomers. DPGME exhibits low acute toxicity by the oral, dermal, and inhalation routes. The oral LD50 ranges 5180-5400 mg/kg b.w. in rats to 7500 mg/kg b.w. in dogs. Dermal LD50 values were reported to range from 9500 to >19000 mg/kg b.w. in rabbits. Acute inhalation exposures to 500 ppm (3000 mg/m 3 , highest attainable concentration) DPGME produced no lethality and mild, but reversible narcosis in rats. In animal and human studies, DPGME is neither a skin sensitizer nor a skin irritant, and was only slightly irritating to the eye. In repeated dose inhalation studies, NOAELs of >50 ppm to 200 ppm (> 303 mg/m3 to 1212 mg/m3 ) have been observed using rats, mice, rabbits, guinea pigs, and monkeys. Effects observed at higher dose levels (1818 mg/m3 to 2424 mg/m3 ; 300 – 400 ppm) showed signs of central nervous system depression and adaptive liver changes. In rats exposed to up to 1000 mg/kg-day DPGME via gavage for 4 weeks, tentative salivation (immediately after dosing) and adaptive liver changes were observed in animals exposed to the highest dose. No effects were observed in rats exposed to 200 mg/kg-day. Studies in rats and rabbits showed that DPGME is not teratogenic (two inhalation studies with NOAELs of 1818 mg/m3 ; 300 ppm). It should be noted that the beta isomer of PGME is known developmental toxicant. This isomer is unlikely to be a metabolite of DPGME. The available data indicate that DPGME is not genotoxic. Information collected for a structurally similar chemical (PGME) suggests that DPGME is not a reproductive toxicant, and is not carcinogenic. Additionally, no effects were seen on the testes and ovaries in a 90-day repeat dose inhalation toxicity study on DPGME.DPGME is not persistent in the environment and is not expected to bioaccumulate in food webs. DPGME has a water solubility value of 1000 mg/L, a vapor pressure of 0.37 hPa and a log Kow of 0.0061. The half-life of DPGME in air was measured at 5.3 hours and is estimated to be 3.4 hours due to direct reactions with photochemically generated hydroxyl radicals. DPGME is readily biodegraded under aerobic conditions, but only slightly degraded under anaerobic conditions. Although environmental monitoring data are not available for DPGME, fugacity-based modelling indicates that DPGME is likely to partition to water compartments in the environment (surface water, groundwater). Acute toxicity testing in fish, invertebrates, and algae indicate a low order of toxicity with effect concentrations exceeding 1000 mg/L. Applying an uncertainty factor of 100 to the 48- hour LC50 value of 1919 mg/L for Daphnia, a PNEC of 19 mg/L was derived. DPGME is a mixture of four isomers. According to the manufacturers specification, (BUA Reports 173 and 174: Methoxypropanol (propylene glycol methyl ether), Dipropylene glycol ethyl ether. GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance), the respective fractions of the structural isomers are 40-50% 1-(2-methoxypropoxy)propanol-2 (CASRN: 13429-07-7), 40-45% 1 -(2-methoxy-1-methylethoxy)propanol-2 (CASRN: 20324-32-7), 2-5% 2-(2-methoxypropoxy)propanol-1 (CASRN: 13588-28-8), and 3-5% 2-(2-methoxy-1- methylethoxy)propanol-1 (CASRN: 55956-21-3). Commercial DPGME is produced only as a four-isomer mixture and hence all testing was conducted on the commercial mixture. The four individual isomers are not separated nor produced as individual chemicals. DPGME is widely used in industrial, commercial, automotive, and household cleaners. As such, inhalation and dermal exposures are likely for worker and consumer populations. In addition, indirect exposures via the environment (i.e., ingestion of surface water) are also possible. Each of these exposure scenarios is discussed below.Products containing DPGME generally contain levels between 1 and 10%, although some products may have levels that are as high as 50% (BUA, 1995). Consumer exposure to DPGME occurs through application of products including cleaning products, paints, and cosmetic agents as well as their residues in packaging (e.g. in packaging). A temporary accumulation of DPGME can occur in closed rooms through the use of DPGME in water-based ceiling and wall paint. In one study, 15 workplace measurements conducted during painting, DPGME concentrations of 30-40 mg/m3 (5-7ppm) were measured in the air.Although tests on commercial PGME have indicated a low potential for toxicity the pure beta isomer of PGME (present at levels £ 0.5% in commerical PGME) has produced developmental effects in animals (BASF, 1988; Hellwig et al., 1994). Unlike the alpha PGME isomer, the beta PGME isomer is an excellent substrate for alcohol/aldehyde dehydrogenases and is oxidized primarily to 2-methoxypropionic acid (2- MPA) (Miller et al., 1986). It is this alkoxyacid metabolite that is the likely mediator of developmental toxicity (Carney et al., 2000). DPGME differs from PGME in that it does not contain beta isomer and hence the formation of the primary alcohol, beta PGME, from DPGME is dependent upon the potential to hydrolyze the central ether linkage in certain isomers of DPGME. Only two of the 4 DPGME isomers have the potential to be hydrolyzed to beta PGME. If one assumes that 100% cleavage of the ether bridge occurs, only 0.6 mmol of 2-MPA can be theoretically produced for every mmol of DPGME. Although DPGME has not been studied directly for the ability to produce beta PGME, a pharmacokinetic study with a structurally similar dipropylene glycol ether, dipropylene glycol dimethyl ether (DPGDME) showed a very low potential for cleavage of the glycol ether backbone with only 4.3% of the theoretical maximum of 2-MPA recovered at low doses and 13% of the theoretical maximum at higher doses (Mendrala et al., 1993). In an in vitro liver slice metabolism assay used to investigate the formation of 2-MPA from six propylene glycol ethers including beta PGME and DPGDME, none of the di- or triether substrates evaluated were metabolized to 2- MPA as effectively as beta-PGME. The in vitro formation of 2-MPA from beta PGME ranged from 3-170- fold higher than from any of the diethers tested (Pottenger et al., 1995). The in vivo metabolism study with DPGME taken together with the in vivo and in vitro studies with structurally analogous diglycol ethers indicate that hydrolysis of the central ether linkage to form the primary alcoholbeta PGME and subsequent hydrolysis to the alkoxyacid metabolite is a minor metabolic pathway for DPGME. This minor pathway is likely to result in levels of MPA that are well below the levels that produce toxicologically significant effects even at high doses of DPGME. Although tests on commercial DPGME and PGME have been negative in developmental studies the pure beta isomer of PGME (present at levels £ 0.5% in commerical PGME) has produced developmental effects in animals (BASF, 1988; Hellwig et al., 1994). Unlike the alpha PGME isomer, the beta PGME isomer is an excellent substrate for alcohol/aldehyde dehydrogenases and is oxidized primarily to 2-methoxypropionic acid (2-MPA) (Miller et al., 1986). It is this alkoxyacid metabolite that is the likely mediator of developmental toxicity (Carney et al., 2000). DPGME differs from PGME in that it does not contain beta isomer thus the formation of the primary alcohol, beta PGME, from DPGME is dependent upon the potential to hydrolyze the central ether linkage in certain isomers of DPGME. Only two of the 4 DPGME isomers have the potential be hydrolyzed to beta PGME. In vivo and in vitro studies provide support that significant cleavage of the dipropylene glycol backbone does not occur (Mendrala et al., 1993; Pottenger et al., 1995) precluding the formation of levels of beta PGME capable of producing toxicologically significant effects even at very high doses of DPGME. The low potential to generate the beta PGME isomer taken together with negative results in developmental toxicity studies in multiple species indicate it is unlikely that DPGME would be teratogenic of fetoxic by oral ingestion or inhalation.Commercial Dipropylene Glycol Methyl Ether (DPGME) is a mixture of four isomers. DPGME exhibits low acute toxicity by the oral, dermal, and inhalation routes. The oral LD50 ranges 5180-5400 mg/kg in rats to 7500 mg/kg in dogs. Dermal LD50 values were reported to range from 9500 to >19000 mg/kg in rabbits. Acute inhalation exposures to 500 ppm DPGME produced mild, but reversible narcosis in rats. DPGME is not a skin sensitizer or skin irritant, and was only slightly irritating to the eye. In repeated dose studies, NOAELs of >50 ppm to 3000 ppm have been observed in inhalation studies using rats, mice, rabbits, guinea pigs, and monkeys. Observations included central nervous system (CNS) effects, adaptive hepatic changes, and decreases in body weight gain. In rats exposed to either 0, 40, 200, or 1000 mg/kg-day DPGME via gavage for 4 weeks, tentative salivation (immediately after dosing) and liver effects (increased relative liver weight, centrilobular hypertrophy) was observed in animals exposed to the highest dose. No effects were observed in rats exposed to 200 mg/kg-day. Studies in rats and rabbits showed that DPGME is not teratogenic (two inhalation studies with NOAELs of 300 ppm). The weight of the evidence indicates that DPGME is not genotoxic. Information collected for a structurally similar chemical (PGME) suggests that DPGME is not a reproductive toxicant, and is not carcinogenic. Additionally, no effects were seen on the testes and ovaries in a 28-day repeat dose oral toxicity study on DPGME. In humans, concentrations of 35-75 ppm may be expected to produce irritation to the eyes, nose, throat, and respiratory tract. Therefore, human exposures to concentrations of DPGME greater than 75 ppm are expected to be self-limiting.DPGME is not persistent in the environment and is not expected to bioaccumulate in food webs. The half-life of DPGME in air was measured at 5.3 hours and is estimated to be 3.4 hours due to direct reactions with photochemically generated hydroxyl radicals. DPGME is readily biodegraded under aerobic conditions, but only slightly degraded under anaerobic conditions. Although environmental monitoring data are not available for DPGME, fugacity-based modeling indicates that PGME is likely to partition to water compartments in the environment (surface water, groundwater). Acute toxicity testing in fish, invertebrates and algae indicate a very low order of toxicity with effect concentrations exceeding 1000 mg/L. A PNEC of 19 mg/L was derived by applying an uncertainty factor of 100 to the 48-hour LC50 value of 1919 mg/L for daphnids.Approximately 38 million pounds (17 thousand tons) of DPGME were produced in the U.S. in 1999 (Appendix A). Approximately 12,000 tons of DPGME were consumed in the U.S. in 1995 (Staples and Davis, 2001). Production in the U.S. was estimated at 35 million pounds (16 thousand tons) for 2000 (Chemical Economics Handbook on Glycol Ethers (1996), SRI International). DPGME occurred in 123 products present on the Swedish market in July 1989. DPGME is used in the manufacture of a wide variety of industrial and commercial products, including paints, varnishes, inks, and cleaners. In the US in 1999, DPGME was used as follows: 58% paints/coatings/inks, 28% cleaners, 10% DPGME acetate production and 3% miscellaneous production. Exposures to DPGME are likely to occur for workers and consumers. Inhalation exposures to relatively high concentrations of DPGME are believed to be self-limiting due to the irritant effects of the chemical. Use of protective gloves to minimize absorption is recommended when prolonged dermal exposures to DPGME are anticipated.
DIPROPYLENE GLYCOL METHYL ETHER
Dipropylene glycol methyl ether is a colorless liquid with a mild, ether-like odor.
Dipropylene glycol methyl ether is completely soluble in water and is miscible with a number of organic solvents, for example ethanol, carbon tetrachloride, benzene, petroleum ether and monochlorobenzene.


CAS Number: 34590-94-8
EC Number: 252-104-2
MDL Number: MFCD00059604
Linear Formula: CH3OC3H6OC3H6OH
Molecular Formula: C₇H₁₆O₃


Dipropylene glycol methyl ether (also known as Methoxy Propoxy Propanol, Oxybispropanol, dipropylene glycol methyl ether, DPM, and Dowanol DPM) is a propylene oxide-based/P series glycol ether and has the formula C7H16O3.
Dipropylene glycol methyl ether is a clear, colourless, viscous liquid which has a slight ether odour.


Dipropylene glycol methyl ether is a colourless, hygroscopic, high boiling liquid with a mild odour.
Dipropylene glycol methyl ether is miscible in any proportion with water and many organic solvents and has good solvent power for nitrocellulose and dyestuffs.


Dipropylene glycol methyl ether is a mid-to slow evaporating solvent.
This hydrophilic solvent, Dipropylene glycol methyl ether, has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.


Dipropylene glycol methyl ether has a higher flash point than propylene glycol methyl ether (PM) making it easier to handle, store, and ship.
More broadly, its hydrophilic nature makes Dipropylene glycol methyl ether an ideal coupling aid in water reducible coatings, and cleaning applications.


Dipropylene glycol methyl ether is a clear colorless liquid with a mild ethereal odor in moderate concentrations.
Dipropylene glycol methyl ether is a colorless liquid with a mild and pleasant odor.
Dipropylene glycol methyl ether is a solvent used in paints, pastes, dyes, resins, brake fluids, inks and in making cosmetics.


Dipropylene glycol methyl ether is also a chemical intermediate in the production of Dipropylene glycol monomethyl ether acetate or DPMA.
Dipropylene glycol methyl ether is a colorless, weakly odorous organic solvent with a molecular weight of 148.2 that is used in a variety of industrial and commercial applications.


Dipropylene glycol methyl ether is typically composed of a combination of four isomers.
In addition, Dipropylene glycol methyl ether is soluble in water.
Dipropylene glycol methyl ether (also known as Methoxy Propoxy Propanol, Oxybispropanol, dipropylene glycol methyl ether, DPM, and Dowanol DPM) is a propylene oxide-based/P series glycol ether and has the formula C7H16O3.


Dipropylene glycol methyl ether is a clear, colourless, viscous liquid which has a slight ether odour.
Dipropylene glycol methyl ether is a clear, colorless, combustible liquid with a slight ether odor.
Dipropylene glycol methyl ether is completely soluble in water, and has moderate volatility.


Dipropylene glycol methyl ether is a propylene oxide-based, or P-series, glycol ether.
Dipropylene glycol methyl ether is a colorless liquid with a mild, ether-like odor.
Dipropylene glycol methyl ether is an organic solvent with a variety of industrial and commercial uses.


Dipropylene glycol methyl ether finds use as a less volatile alternative to propylene glycol methyl ether and other glycol ethers.
Dipropylene glycol methyl ether is typically a mixture of four isomers.
Dipropylene glycol methyl ether is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.



USES and APPLICATIONS of DIPROPYLENE GLYCOL METHYL ETHER:
Dipropylene glycol methyl ether is a very useful industrial and commercial chemical.
One of Dipropylene glycol methyl ether's main commercial uses is as a solvent for paints, varnishes, inks, strippers, and degreasers.
Dipropylene glycol methyl ether is also utilised as a coalescing agent for water-based paints and inks where it promotes polymer fusing during the drying process.


Dipropylene glycol methyl ether is also a component of wood and coil coatings, as well as coatings used in the automotive industry, industrial maintainence, and metal finishing.
Dipropylene glycol methyl ether is also a component of hydraulic fluids and industrial degreasers and is a chemical additive in the oil production and drilling industry.


Dipropylene glycol methyl ether is also practically non- toxic and hygroscopic, and thus lends itself well to commercial and industrial use.
Dipropylene glycol methyl ether is a very useful chemical building block in the manufacture of many products.
This is due to its reaction with acids, forming esters and oxidising agents which produce aldehydes, carboxylic acids and alkali metals therefore creating alcoholates and acetals.


It is this flexibility that supports the use of Dipropylene glycol methyl ether across a range of industries and therefore makes it a component of many household items that people use every day.
Dipropylene glycol methyl ether is found in ceiling and wall paints and in many common cleaners including glass and surface cleaners, paint-brush cleaners, all-purpose cleaners, carpet cleaners and disinfectant cleaners.


Dipropylene glycol methyl ether is also found in cosmetics where it provides emollient properties and product stabilisation as well as floor and aluminium polish, leather and textile dyes, rust removers and pesticides where it acts as a stabiliser.
It is commonly utilized as a less volatile option to Dipropylene glycol methyl ether and other glycol ethers.


Dipropylene glycol methyl ether is typically composed of a combination of four isomers.
In addition, Dipropylene glycol methyl ether is soluble in water.
Dipropylene glycol methyl ether is used coupling agent (often in blends) for water-based dilutable coatings.


Dipropylene glycol methyl ether is used Fragrance carrier for reed diffusers
Dipropylene glycol methyl ether is used Active solvent for solvent-based coatings.
Dipropylene glycol methyl ether is used Coupling agent and solvent in household and industrial cleaners, grease and paint removers, metal cleaners, and hard surface cleaners.


Dipropylene glycol methyl ether is used Tail solvent for solvent-based gravure and flexographic printing inks.
Dipropylene glycol methyl ether is used Primary solvent in solvent-based silk screen printing inks.
Dipropylene glycol methyl ether is used Coupling agent in solvent blends for water-based gravure, flexographic, and silk screen printing inks.


Dipropylene glycol methyl ether is used Coupling agent and solvent for vat dyeing fabrics.
Dipropylene glycol methyl ether is used Stabilizer for agricultural herbicides.
Dipropylene glycol methyl ether is used Coalescent for floor polishes and finishes.


Dipropylene glycol methyl ether is suitable for styrene acrylic emulsion, acrylic emulsion and latex paint system.
Dipropylene glycol methyl ether is used in upscale electrophoresis paint and all kinds of high-grade paint solvents.
Dipropylene glycol methyl ether is also used in fuel antifreeze, cleaning agents, extraction solvent, flexo printing ink, screen printing ink, non-ferrous metal ore dressing agent.


Dipropylene glycol methyl ether is also used as raw material in organic synthesis.
Dipropylene glycol methyl ether is used in hydraulic fluids and as a solvent.
Dipropylene glycol methyl ether is a solvent used in paints, pastes, dyes, resins, brake fluids, inks and in making cosmetics.


Dipropylene glycol methyl ether intermediate evaporation rate allows it to be used in a potentially wider range of systems than many other solvents.
Dipropylene glycol methyl ether may be a lachrymator as is the chemically related propylene glycol monomethyl ether.
Dipropylene glycol methyl ether is used in manufacture of various cosmetics.
Dipropylene glycol methyl ether is used in preparation of special cleaning agent for pot bottom black dirt.


Dipropylene glycol methyl ether is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Dipropylene glycol methyl ether is used in the following products: coating products, anti-freeze products, lubricants and greases, biocides (e.g. disinfectants, pest control products) and inks and toners.


Other release to the environment of Dipropylene glycol methyl ether is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).


Other release to the environment of Dipropylene glycol methyl ether is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).


Dipropylene glycol methyl ether can be found in complex articles, with no release intended: vehicles.
Dipropylene glycol methyl ether can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery), wood (e.g. floors, furniture, toys), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and plastic (e.g. food packaging and storage, toys, mobile phones).


Dipropylene glycol methyl ether is used in the following products: fuels, laboratory chemicals, coating products and plant protection products.
Dipropylene glycol methyl ether is used in the following areas: building & construction work, printing and recorded media reproduction and agriculture, forestry and fishing.
Dipropylene glycol methyl ether is used for the manufacture of: machinery and vehicles, plastic products, mineral products (e.g. plasters, cement) and furniture.


Other release to the environment of Dipropylene glycol methyl ether is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Dipropylene glycol methyl ether is used in the following products: air care products, plant protection products, coating products, washing & cleaning products, biocides (e.g. disinfectants, pest control products), fillers, putties, plasters, modelling clay, lubricants and greases, perfumes and fragrances, polishes and waxes and cosmetics and personal care products.


Release to the environment of Dipropylene glycol methyl ether can occur from industrial use: formulation of mixtures.
Dipropylene glycol methyl ether is used in the following products: coating products, fillers, putties, plasters, modelling clay, inks and toners, lubricants and greases and polymers.
Dipropylene glycol methyl ether is used for the manufacture of: chemicals.


Release to the environment of Dipropylene glycol methyl ether can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release and as an intermediate step in further manufacturing of another substance (use of intermediates).
Release to the environment of Dipropylene glycol methyl ether can occur from industrial use: manufacturing of the substance, formulation of mixtures, in processing aids at industrial sites and as an intermediate step in further manufacturing of another substance (use of intermediates).



HOW IS DIPROPYLENE GLYCOL METHYL ETHER PRODUCED:
Dipropylene glycol methyl ether is produced by the reaction of propylene oxide with methanol using a catalyst.



HOW IS DIPROPYLENE GLYCOL METHYL ETHER STORED AND DISTRIBUTED:
Dipropylene glycol methyl ether is stored in mild steel and /or stainless steel tanks and/or drums and can be transported by bulk vessels or tank trucks.
Dipropylene glycol methyl ether should be stored away from heat and sources of ignition in a cool and well-ventilated area.
Dipropylene glycol methyl ether has a specific gravity of 0.95 and a flashpoint of 75oC (closed cup) and is not regulated for any form of transport.



PHYSICAL and CHEMICAL PROPERTIES of DIPROPYLENE GLYCOL METHYL ETHER:
Chemical formula: C7H16O3
Molar mass: 148.202 g·mol−1
Density: 0.951 g/cm3
Boiling point: 190 °C (374 °F; 463 K)
Solubility in water: Miscible
Flash point: 75 °C (167 °F; 348 K)
Physical state: liquid
Color: colorless
Odor: mild
Melting point/range: -83 °C - lit.
Initial boiling point and boiling range: 190 °C - lit.
Flammability (solid, gas): No data available
Upper explosion limit: 14 %(V)
Lower explosion limit: 1,1 %(V)
Flash point: 74 °C - closed cup
Autoignition temperature: 207 °C at 1.013 hPa
Decomposition temperature: No data available
pH: No data available
Viscosity Viscosity, kinematic: 4,55 mm2/s at 20 °C3,82 mm2/s at 25 °C
Viscosity, dynamic: No data available
Water: solubility soluble

Partition coefficient: n-octanol/water log Pow: 0,004 at 25 °C
Vapor pressure: 0,5 hPa at 25 °C
Density: 0,951 g/cm3 at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Surface tension: 68,7 mN/m at 20 °C
Molecular Formula / Molecular Weight: C7H16O3 = 148.20
Physical State (20 deg.C): Liquid
CAS RN: 34590-94-8
PubChem Substance ID: 87567626
SDBS (AIST Spectral DB): 7945
Merck Index (14): 3344
MDL Number: MFCD00059604
CAS number: 34590-94-8
EC number: 252-104-2
Hill Formula: C₇H₁₆O₃
Chemical formula: (CH₃O)C₃H₆OC₃H₆(OH)
Molar Mass: 148.2 g/mol
HS Code: 2909 49 80
Boiling point: 184 °C (1013 hPa)

Density: 0.95 g/cm3 (20 °C)
Explosion limit: 1.1 - 14 %(V)
Flash point: 75 °C
Ignition temperature: 205 °C DIN 51794
Melting Point: -83 °C
pH value: 6 - 7 (200 g/l, H₂O, 20 °C)
Vapor pressure: 0.75 hPa (25 °C)
Formula: CH3O[CH2CH(CH­3)O]2H
CAS No: 34590-94-8
Molar mass: 148.2 g mol-1
Density: 0.951 g/cm, liquid
Boiling Point: 190 C
Viscosity: 3.7 cP at 25 C
Evaporation Rate (n-butyl acetate=1): 0.035
Boiling point: 408°F
Molecular weight: 148.2
Freezing point/melting point: -112°F
Vapor pressure: 0.5 mmHg
Flash point: 166°F
Vapor density: 5.11
Specific gravity: 0.95
Ionization: potential
Lower explosive limit (LEL): 1.1% at 392°F
Upper explosive limit (UEL): 3%

NFPA health rating: 2
NFPA fire rating: 2
NFPA reactivity rating: 0
Melting Point: -80.0°C
Density: 0.9500g/mL
Boiling Point: 180.0°C
Flash Point: 75°C
Assay Percent Range: 98.5% min. sum of isomers (GC)
Packaging: Glass bottle
Linear Formula: CH3O(CH2)3O(CH2)3OH
Merck Index: 15, 3384
Specific Gravity: 0.95
Solubility Information: Solubility in water: soluble. Other solubilities: miscible with benzene
Viscosity: 4 mPa.s (25°C)
Formula Weight: 148.2
Formula: C7H16O3
Formula mass: 148.20
Melting point, °C: -80
Boiling point, °C: 190
Vapor pressure, mmHg: 0.4 (25 C)
Vapor density (air=1): 5.11

Saturation Concentration: 0.05% (500 ppm) at 25 C (calculated)
Evaporization number: 0.02 (butyl acetate = 1)
Density: 0.951 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 3.5 cp @ 25C
Surface tension: 28.8 g/s2
Refractive index: 1.419 (25 C)
Chemical Formula: C7H16O2
Spec. No: PR/DPM/17/07-01
CAS NO.: 34590-94-8
UN No.: - (non-hazardous for transport)
Molecular Weight: 148.2g/mol
Appearance: clear colourless liquid
Purity (%): 99.0 min
Acidity (%): 0.02 max
Color (Pt-Co): 15 max
Distillation range (℃): 180-195
Specific gravity at 20(℃): 0.945-0.950



FIRST AID MEASURES of DIPROPYLENE GLYCOL METHYL ETHER:
-Description of first-aid measures:
*General advice:
Consult a physician.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of DIPROPYLENE GLYCOL METHYL ETHER:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of DIPROPYLENE GLYCOL METHYL ETHER:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
-Further information:
Use water spray to cool unopened containers.



EXPOSURE CONTROLS/PERSONAL PROTECTION of DIPROPYLENE GLYCOL METHYL ETHER:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 30 min
*Body Protection:
Impervious clothing
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.



HANDLING and STORAGE of DIPROPYLENE GLYCOL METHYL ETHER:
-Precautions for safe handling:
*Advice on safe handling:
No smoking.
Take measures to prevent the build up of electrostatic charge.
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place



STABILITY and REACTIVITY of DIPROPYLENE GLYCOL METHYL ETHER:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.



SYNONYMS:
DOWANOL DPM
Dipropylene glycol monomethyl ether
(2-methoxymethylethoxy)propanol
dipropylene glycol monomethyl ether
(2-methoxymethylethoxy)propanol
1-(2-methoxy-1-methylethoxy)-2-propanol
1-(2-methoxyisopropoxy)-2-propanol
1,4-dimethyl-3,6-dioxa-1-heptanol
2-(3-methoxypropoxy)propan-1-ol
2-methoxymethylethoxypropanol
3-(3-methoxypropoxy)1-propanol
dipropylene glycol methyl ether
glycol ether DPM
methyl dipropanol
oxybispropanol methyl ether
PPG-2 methyl ether
propanol, (2-methoxymethylethoxy)-
propasol solvent DM
dipropylene glycol monomethyl ether
(2-methoxymethylethoxy)propanol
bis-(2-methoxypropyl) ether
1(or 2)-(2-Methoxymethylethoxy)propanol
Arcosolv DPM
DPM
Dipropylene Glycol Methyl Ether
Dowanol DPM
EBJ 105
Forguard M
Glysolv DPM
Hisolve DPM
Kino-red
Methoxypropoxypropanol
Methyl Dipropasol
Methyl Propylene Di Glycol
Oxybispropanol Methyl Ether
PPG-2 Methyl Ether;
Methoxy dipropanol
Ucar solvent 2LM
Dowanol DPM,
Dowanol-50B
DPGME
PPG-2 methyl ether
Bis(2-(methoxypropyl) ether
Dipropylene glycol monomethyl ether
Dipropylene glycol methyl ether
(2-Methoxymethylet­hoxy)propanol
HSDB 2511
Propanol
(2-methoxymethylet­hoxy)-
Dipropylene glycol
monomethyl ether
EINECS 252-104-2
1-Propanol
2-(2-methoxypropoxy)-
CID25485
1-(2-Methoxyisopropoxy)-2-propanol
1,4-Dimethyl-3,6-dioxa-1-heptanol
(2-Methoxymethylethoxy)propanol
Arcosolv DPM
Dipropylene glycol methyl ether
Dipropylene glycol monomethyl ether
Dowanol DPM
Dowanol-50B
Glysolv DPM
Kino-red
PPG-2 methyl ether
Ucar solvent 2LM
Dipropylene glycol methyl ether
Dipropylene glycol monomethyl ether
PPG-2 methyl ether
Propanol, (2-methoxymethylethoxy)-
(2-Methoxymethylethoxy)propanol
PPG 2 Methyl Ether
Dipropylene glycol monomethyl ether
1,4-Dimethyl-3,6-dioxa-1-heptanol




DIPROPYLENE GLYCOL METHYL ETHER (DPGME)
Dipropylene Glycol Methyl Ether (DPGME) is colorless transparent viscous liquid with a pleasant odor.
Dipropylene Glycol Methyl Ether (DPGME) is miscible with water and a variety of organic solvents.
Dipropylene Glycol Methyl Ether (DPGME) appears as a colorless and clear liquid.


CAS Number: 34590-94-8 (mixture of isomers)
EC Number: 252-104-2
MDL Number: MFCD00059604
Linear Formula: CH3OC3H6OC3H6OH
Molecular Formula: C₇H₁₆O₃



SYNONYMS:
DOWANOL DPM, Dipropylene glycol monomethyl ether, (2-methoxymethylethoxy)propanol, dipropylene glycol monomethyl ether, (2-methoxymethylethoxy)propanol, 1-(2-methoxy-1-methylethoxy)-2-propanol, 1-(2-methoxyisopropoxy)-2-propanol, 1,4-dimethyl-3,6-dioxa-1-heptanol, 2-(3-methoxypropoxy)propan-1-ol, 2-methoxymethylethoxypropanol, 3-(3-methoxypropoxy)1-propanol, dipropylene glycol methyl ether, glycol ether DPM, methyl dipropanol, oxybispropanol methyl ether, PPG-2 methyl ether, propanol, (2-methoxymethylethoxy)-, propasol solvent DM, dipropylene glycol monomethyl ether, (2-methoxymethylethoxy)propanol, bis-(2-methoxypropyl) ether, 1(or 2)-(2-Methoxymethylethoxy)propanol, Arcosolv DPM, DPM, Dipropylene Glycol Methyl Ether, Dowanol DPM, EBJ 105, Forguard M, Glysolv DPM, Hisolve DPM, Kino-red, Methoxypropoxypropanol, Methyl Dipropasol, Methyl Propylene Di Glycol, Oxybispropanol Methyl Ether, PPG-2 Methyl Ether, Methoxy dipropanol, Ucar solvent 2LM, Dowanol DPM, Dowanol-50B, DPGME, PPG-2 methyl ether, Bis(2-(methoxypropyl) ether, Dipropylene glycol monomethyl ether, Dipropylene glycol methyl ether, (2-Methoxymethylet­hoxy)propanol, DPM, dpgme, (2-methoxymethylethoxy)propanol, DI(PROPYLENE GLYCOL) METHYL ETHER, arcosolv, GLYCOL ETHER DPM, Methoxypropoxypropanol, Dipropylene glycol monomethyl, (2-methoxymethylethoxy)-propano, 3-(3-Methoxypropoxy)-1-propanol
Glycol Ether DPM, DPGME, solvent DM, DPM solvent, propasol, 2-(2-methoxymethylethoxy), Propanol, 1(or 2)-(2-methoxymethylethoxy)-, (2-Methoxymethylethoxy)propanol, Arcosolv DPM, Dipropylene glycol methyl ether, Dipropylene glycol monomethyl ether, Dowanol DPM, Dowanol-50B, Glysolv DPM, Kino-red, PPG-2 methyl ether, Ucar solvent 2LM, Methoxy dipropanol, Ucar solvent 2LM, Dowanol DPM, Dowanol-50B, DPGME, PPG-2 methyl ether, Bis(2-(methoxypropyl) ether, Dipropylene glycol monomethyl ether, Dipropylene glycol methyl ether, (2-Methoxymethylet­hoxy)propanol, HSDB 2511, Propanol, (2-methoxymethylet­hoxy)-, Dipropylene glycol, monomethyl ether, EINECS 252-104-2, 1-Propanol, 2-(2-methoxypropoxy)-, CID25485, 1-(2-Methoxyisopropoxy)-2-propanol, 1,4-Dimethyl-3,6-dioxa-1-heptanol, Dipropylene glycol monomethyl ether, Dipropylene glycol methyl ether, Methoxypropoxypropanol, (2-methoxymethylethoxy) propanol, 2-(2-methoxypropoxy)propanol, DPM glycol ether, DPGME, 1-(2-methoxy-1-methylethoxy)-2-propanol, 1-(2-methoxyisopropoxy)-2-propanol, HSDB 2511, Propanol, (2-methoxymethylet­hoxy)-, Dipropylene glycol monomethyl ether, EINECS 252-104-2, 1-Propanol, 2-(2-methoxypropoxy)-, CID25485, 1-(2-Methoxyisopropoxy)-2-propanol, 1,4-Dimethyl-3,6-dioxa-1-heptanol, (2-Methoxymethylethoxy)propanol, Arcosolv DPM, Dipropylene glycol methyl ether, Dipropylene glycol monomethyl ether, Dowanol DPM, Dowanol-50B, Glysolv DPM, Kino-red, PPG-2 methyl ether, Ucar solvent 2LM, Dipropylene glycol methyl ether, Dipropylene glycol monomethyl ether, PPG-2 methyl ether, Propanol, (2-methoxymethylethoxy)-, (2-Methoxymethylethoxy)propanol, PPG 2 Methyl Ether, Dipropylene glycol monomethyl ether, 1,4-Dimethyl-3,6-dioxa-1-heptanol, 2-(2-methoxypropoxy)propan-1-ol, Dipropylene glycol methyl ether, 13588-28-8, 2-(2-METHOXYPROPOXY)-1-PROPANOL, 1-Propanol, 2-(2-methoxypropoxy)-, 2-(2-methoxypropoxy)propanol, SCHEMBL16073, dipropyleneglycol monomethyl ether, DTXSID80864425, AKOS037648698, NCGC00090688-04, BS-15252, CS-0154037, NS00095810, D81108, J-019668, J-520393, Q2954819



Dipropylene Glycol Methyl Ether (DPGME) is a clear, colourless liquid with a faint ether-like odour.
Dipropylene Glycol Methyl Ether (DPGME) is soluble in water and has moderate volatility.
Dipropylene Glycol Methyl Ether (DPGME) is produced by reacting propylene oxide with methanol using a catalyst.


Dipropylene Glycol Methyl Ether (DPGME) is a mixture of four structural isomers: 1-(2-methoxypropoxy)propanol-2, 1-(2-methoxy-1-methylethoxy)propanol-1, 2-(2-methoxypropoxy)propanol-1 and 2-(2-methoxy-1-methylethoxy)propanol-1.
Dipropylene Glycol Methyl Ether (DPGME) is a mid-to slow evaporating solvent.


This hydrophilic solvent, Dipropylene Glycol Methyl Ether (DPGME), has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.
Dipropylene Glycol Methyl Ether (DPGME) has a higher flash point than propylene glycol methyl ether (PM) making it easier to handle, store, and ship.


More broadly, its hydrophilic nature makes Dipropylene Glycol Methyl Ether (DPGME) an ideal coupling aid in water reducible coatings, and cleaning applications.
Dipropylene Glycol Methyl Ether (DPGME) intermediate evaporation rate allow it to be used in a potentially wider range of systems than many other solvents


Dipropylene Glycol Methyl Ether (DPGME) appears as a colorless and clear liquid.
Dipropylene Glycol Methyl Ether (DPGME) is an organic solvent with a variety of industrial and commercial uses.
Dipropylene Glycol Methyl Ether (DPGME) finds use as a less volatile alternative to propylene glycol methyl ether and other glycol ethers.


The commercial product, Dipropylene Glycol Methyl Ether (DPGME), is typically a mixture of four isomers
Dipropylene Glycol Methyl Ether (DPGME) is a colorless liquid with a weak odor.
Dipropylene Glycol Methyl Ether (DPGME) is multipurpose environmentally friendly cleaner solvent, have good stability, very excellent solubility, and its impact on human health, higher security.


Dipropylene Glycol Methyl Ether (DPGME) also can be instead of NMP used for cleaning agent in the electronics industry.
And Dipropylene Glycol Methyl Ether (DPGME) is a important material raw matsynthesis of polyurethane.
Dipropylene Glycol Methyl Ether (DPGME) is produced by the reaction of propylene oxide with methanol using a catalyst.


Dipropylene Glycol Methyl Ether (DPGME) is a colorless liquid with a mild, ether-like odor.
Dipropylene Glycol Methyl Ether (DPGME) is a mid-to slow evaporating solvent.
This hydrophilic solvent has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.


Dipropylene Glycol Methyl Ether (DPGME) has a higher flash point than propylene glycol methyl ether (PM) making it easier to handle, store, and ship.
Dipropylene Glycol Methyl Ether (DPGME) is a clear, colourless liquid with a faint ether-like odour.
Dipropylene Glycol Methyl Ether (DPGME) is soluble in water and has moderate volatility.


Dipropylene Glycol Methyl Ether (DPGME) is produced by reacting propylene oxide with methanol using a catalyst.
Dipropylene Glycol Methyl Ether (DPGME) is a mixture of four structural isomers: 1-(2-methoxypropoxy)propanol-2, 1-(2-methoxy-1-methylethoxy)propanol-1, 2-(2-methoxypropoxy)propanol-1 and 2-(2-methoxy-1-methylethoxy)propanol-1.


Dipropylene Glycol Methyl Ether (DPGME) is a colorless liquid with a weakodor.
Molecular weight of Dipropylene Glycol Methyl Ether (DPGME) is 148.23; Specific gravity(H2O:1) 5 0.95; Boiling point = 180℃; Freezing/Meltingpoint = 2 80℃; Vapor pressure= 0.5 mmHg at 20℃; Flash point = 74.6℃ (cc); Autoignition temperature=270℃.


Dipropylene Glycol Methyl Ether (DPGME) is a colorless liquid with a weak odor .
Dipropylene Glycol Methyl Ether (DPGME) is colorless transparent viscous liquid with a pleasant odor.
Dipropylene Glycol Methyl Ether (DPGME) is miscible with water and a variety of organic solvents.


More broadly, its hydrophilic nature makes Dipropylene Glycol Methyl Ether (DPGME) an ideal coupling aid in water reducible coatings, and cleaning applications.
Dipropylene Glycol Methyl Ether (DPGME) intermediate evaporation rate allow it to be used in a potentially wider range of systems than many other solvents.



USES and APPLICATIONS of DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
Dipropylene Glycol Methyl Ether (DPGME) is suitable for benzene propylene emulsion, propylene alkenes acid emulsion and its emulsion paint, which are characterized by reducing the coating temperature, speeding its cohesion and keeping the coating in a good condition.
Dipropylene Glycol Methyl Ether (DPGME) is a clear, colorless liquid with a mild odor.


Dipropylene Glycol Methyl Ether (DPGME) is commonly used as a solvent in various industries such as paints and coatings, cleaners, printing inks, and electronics manufacturing.
Dipropylene Glycol Methyl Ether (DPGME) has excellent solvency power and low evaporation rate, making it suitable for applications that require controlled drying times.


Dipropylene Glycol Methyl Ether (DPGME) is used coupling agent (often in blends) for water-based dilutable coatings.
Dipropylene Glycol Methyl Ether (DPGME) is used fragrance carrier for reed diffusers.
Dipropylene Glycol Methyl Ether (DPGME) is used active solvent for solvent-based coatings.


Dipropylene Glycol Methyl Ether (DPGME) is used coupling agent and solvent in household and industrial cleaners, grease and paint removers, metal cleaners, and hard surface cleaners.
Dipropylene Glycol Methyl Ether (DPGME) is used tail solvent for solvent-based gravure and flexographic printing inks.


Dipropylene Glycol Methyl Ether (DPGME) is used primary solvent in solvent-based silk screen printing inks.
Dipropylene Glycol Methyl Ether (DPGME) is used coupling agent in solvent blends for water-based gravure, flexographic, and silk screen printing inks.
Dipropylene Glycol Methyl Ether (DPGME) is used coupling agent and solvent for vat dyeing fabrics.


Dipropylene Glycol Methyl Ether (DPGME) is used stabilizer for agricultural herbicides.
Dipropylene Glycol Methyl Ether (DPGME) is used coalescent for floor polishes and finishes
Dipropylene Glycol Methyl Ether (DPGME) is primarily used as a solvent in paints, varnishes, printing inks and strippers and in coatings for automotive and architectural applications, wood and coil coatings and metal finishing.


Dipropylene Glycol Methyl Ether (DPGME) is also used as a coalescent agent in water-based paints and inks where it serves to promote polymer fusion during the drying process, as a chemical building block for the production of dipropylene glycol monomethyl ether acetate, and as a chemical additive in the oil and drilling industry.


Dipropylene Glycol Methyl Ether (DPGME) is found in a wide range of household and industrial cleaners including all-purpose cleaners, glass and other surface cleaners, paint brush cleaners, disinfectants and carpet cleaners.
Dipropylene Glycol Methyl Ether (DPGME) is also used as a coupling agent in fabric dyes.


Dipropylene Glycol Methyl Ether (DPGME) is used as a solvent, coupler, emollient and stabilizer in cosmetic products; and as a stabilizer in pesticides and herbicides.
Dipropylene Glycol Methyl Ether (DPGME) is generally used to dissolve organic and inorganic substances.


Solvents such as Dipropylene Glycol Methyl Ether (DPGME) are used to dissolve, transport and mix flavorings in perfumes and fragrance products.
Dipropylene Glycol Methyl Ether (DPGME) allows the ingredients to be distributed homogeneously, to achieve the desired consistency of the product and to dissolve some active ingredients more effectively.


The usage rate varies between 1% and 10% depending on the effect of Dipropylene Glycol Methyl Ether (DPGME) and its interaction with other substances.
Dipropylene Glycol Methyl Ether (DPGME) is used as a solvent, chemical intermediate and coupling agent.
Dipropylene Glycol Methyl Ether (DPGME) is a solvent for paints, varnishes, alkyds, epoxies, polyesters, varnishes, strippers, inks, solvent-based coatings, lacquers, nitrocellulose and synthetic resins, insect repellents, waxes, adhesives, coatings, agricultural products, printing inks.


Dipropylene Glycol Methyl Ether (DPGME) is used as a coupling agent in water-based paints, inks, container dyeing fabrics, floor polishes.
Dipropylene Glycol Methyl Ether (DPGME) is used as a solvent and chemical intermediate for cleaners, coatings, paints, automotive fluids, agricultural products, waxes, adhesives, insect repellents, cosmetics.


Dipropylene Glycol Methyl Ether (DPGME) is used as solvent for PVC stabilizer, nitrocellulose, ethyl cellulose, polyvinyl acetate, paint and paint solvent and brake fluid component.
Dipropylene Glycol Methyl Ether (DPGME) can be used as a solvent of printing ink, enamel paint, cutting fluid and operating oil; water-based paint as a coupling agent (usually used by mixing).


Dipropylene Glycol Methyl Ether (DPGME) is used as the active solvent of water-based paint.
Dipropylene Glycol Methyl Ether (DPGME) is used as a solvent and binding agent of household and industrial cleaners, oil and paint remover, metal and hard surface cleaner.


Dipropylene Glycol Methyl Ether (DPGME) is used as the base solvent and coupling agent of solvent type screen printing ink.
Dipropylene Glycol Methyl Ether (DPGME) is used as solvent and coupling agent of vat dye textile.
Dipropylene Glycol Methyl Ether (DPGME) is used as a binding agent and skin care agent in cosmetic formula.


Dipropylene Glycol Methyl Ether (DPGME) is used as pesticide stabilizer and coagulant floor brightening agent.
Dipropylene Glycol Methyl Ether (DPGME) is used in hydraulic fluids and as a solvent.
Typically Dipropylene Glycol Methyl Ether (DPGME) is used for water and curing coatings.


Dipropylene Glycol Methyl Ether (DPGME) is used as a solvent for nitrocellulose, ethyl cellulose, polyvinyl acetate, and so on.
Dipropylene Glycol Methyl Ether (DPGME) is used paint, dye solvents, but also used as brake oil components.
Dipropylene Glycol Methyl Ether (DPGME) is used as a solvent for nitrocellulose, ethyl cellulose, polyvinyl acetate, etc.


Dipropylene Glycol Methyl Ether (DPGME) is used as a solvent for nitrocellulose, ethyl cellulose, polyvinyl acetate, etc.
Dipropylene Glycol Methyl Ether (DPGME) is used as a solvent for paints and dyes, and also as a brake oil components.
Dipropylene Glycol Methyl Ether (DPGME) is used as a solvent for printing ink and enamel, and also as a solvent for washing of cutting oil and working oil.


Dipropylene Glycol Methyl Ether (DPGME) is used as a coupling agent for water-based dilution coatings (often mixed).
Dipropylene Glycol Methyl Ether (DPGME) can be used as an active solvent for water-based coatings.
Dipropylene Glycol Methyl Ether (DPGME) can also be used as a solvent and coupling agent for household and industrial cleaners, grease and paint removers, metal cleaners, hard surface cleaners.


Dipropylene Glycol Methyl Ether (DPGME) can be used as a base for solvent-based screen printing inks Solvent, coupling agent.
Dipropylene Glycol Methyl Ether (DPGME) can be used as coupling agent and solvent for vat dye fabrics.
Dipropylene Glycol Methyl Ether (DPGME) can be used as coupling agent and skin care agent in cosmetic formulations.


Dipropylene Glycol Methyl Ether (DPGME) can be used as agricultural insecticide Stabilizer of agent.
Dipropylene Glycol Methyl Ether (DPGME) can be used as coagulant of ground brightener.
Dipropylene Glycol Methyl Ether (DPGME) is often used in combination with propylene glycol in cosmetics.


Dipropylene Glycol Methyl Ether (DPGME) is used solvent for nitrocellulose and synthetic resins
Dipropylene Glycol Methyl Ether (DPGME) is used in preparation of special cleaning agent for pot bottom black dirt.
Dipropylene Glycol Methyl Ether (DPGME) is used as solvent for automotive fluids, cleaners, dyes, coatings, inks, waxes, adhesives, agricultural products, insect repellents, and cosmetics; chemical intermediate.


Dipropylene Glycol Methyl Ether (DPGME) is used coupling agent (often in blends) for water-based dilutable coatings.
Dipropylene Glycol Methyl Ether (DPGME) is used fragrance carrier for reed diffusers.
Dipropylene Glycol Methyl Ether (DPGME) is used active solvent for solvent-based coatings.


Dipropylene Glycol Methyl Ether (DPGME) is used coupling agent and solvent in household and industrial cleaners, grease and paint removers, metal cleaners, and hard surface cleaners.
Dipropylene Glycol Methyl Ether (DPGME) is used tail solvent for solvent-based gravure and flexographic printing inks.


Dipropylene Glycol Methyl Ether (DPGME) is used primary solvent in solvent-based silk screen printing inks.
Dipropylene Glycol Methyl Ether (DPGME) is used coupling agent in solvent blends for water-based gravure, flexographic, and silk screen printing inks.
Dipropylene Glycol Methyl Ether (DPGME) is used coupling agent and solvent for vat dyeing fabrics.


Dipropylene Glycol Methyl Ether (DPGME) is used coalescent for floor polishes and finishes
Dipropylene Glycol Methyl Ether (DPGME) is primarily used as a solvent in paints, varnishes, printing inks and strippers and in coatings for automotive and architectural applications, wood and coil coatings, and metal finishing.


Dipropylene Glycol Methyl Ether (DPGME) is also used as a coalescent agent in water-based paints and inks where it serves to promote polymer fusion during the drying process, as a chemical building block for the production of dipropylene glycol monomethyl ether acetate, and as a chemical additive in the oil and drilling industry.


Dipropylene Glycol Methyl Ether (DPGME) is found in a wide range of household and industrial cleaners including all-purpose cleaners, glass and other surface cleaners, paint brush cleaners, disinfectants and carpet cleaners.
Dipropylene Glycol Methyl Ether (DPGME) is used paint, dye solvents, but also used as brake oil components.


Dipropylene Glycol Methyl Ether (DPGME) is used stabilizer for agricultural herbicides.
Dipropylene Glycol Methyl Ether (DPGME) is also used as a coupling agent in fabric dyes; as a solvent, coupler, emollient and stabilizer in cosmetic products; and as a stabilizer in pesticides and herbicides.



CLASS OF DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
Organic Intermediates and Compounds , Solvents - Glycols - Alcohols



INDUSTRY OF DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
Industrial , Industrial Drilling , Oil and Gas Production , Drilling Fluid , Hydraulic Fracturing , Fracking , Organics , Solvents



FUNCTIONS OF DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
*Solvents ,
*Drilling Fluid Additives ,
*Organic Intermediate



CHEMICAL PROPERTIES OF DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
Dipropylene Glycol Methyl Ether (DPGME) is colorless liquid with a mild, pleasant odor.
Because of its structure Dipropylene Glycol Methyl Ether (DPGME) is completely miscible with water and a wide variety of organic substances, and has the combined solubility characteristics of an alcohol, on ether and a hydrocarbon.
Dipropylene Glycol Methyl Ether (DPGME) is used in formulations of brake fluids, lacquers, paints, varnishes, dye and ink solvents, wood stains, textile processes, dry cleaning soaps and cleaning compounds.



CHARACTERISTICS OF DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
Dipropylene Glycol Methyl Ether (DPGME) is a colorless transparent liquid with a faint ether smell.
Dipropylene Glycol Methyl Ether (DPGME) has low toxicity.

Dipropylene Glycol Methyl Ether (DPGME) has low viscosity and low surface tension.
Dipropylene Glycol Methyl Ether (DPGME) has a moderate evaporation rate.
Dipropylene Glycol Methyl Ether (DPGME) has good solubility and coupling ability.

Dipropylene Glycol Methyl Ether (DPGME) is miscible with water and has appropriate HLB value.
Dipropylene Glycol Methyl Ether (DPGME) can dissolve grease, natural resin and rubber, cellulose, polyvinyl acetate, polyvinyl methyl/ethyl/butyraldehyde, alkyd resin, phenolic resin, Polymer chemicals such as urea resin.



GENERAL PROPERTIES OF DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
Dipropylene Glycol Methyl Ether (DPGME) is a colorless, viscous liquid with a slight odor.
Dipropylene Glycol Methyl Ether (DPGME) has moderate volatility and is completely soluble in water.



STORAGE AND HANDLING OF DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
Dipropylene Glycol Methyl Ether (DPGME) should be stored in a cool, well-ventilated place away from sources of ignition and static discharge.
Dipropylene Glycol Methyl Ether (DPGME) must be isolated from incompatible materials such as strong oxidizing and reducing agents, alkali metals and nitrides.



REACTIVITY PROFILE OF DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
Dipropylene Glycol Methyl Ether (DPGME) may react violently with strong oxidizing agents.
Dipropylene Glycol Methyl Ether (DPGME) may initiate the polymerization of isocyanates and epoxides.



PHYSICAL and CHEMICAL PROPERTIES of DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
Chemical formula: C7H16O3
Molar mass: 148.202 g·mol−1
Density: 0.951 g/cm3
Boiling point: 190 °C (374 °F; 463 K)
Solubility in water: Miscible
Flash point: 75 °C (167 °F; 348 K)
Physical state: liquid
Color: colorless
Odor: mild
Melting point/range: -83 °C - lit.
Initial boiling point and boiling range: 190 °C - lit.
Flammability (solid, gas): No data available
Upper explosion limit: 14 %(V)
Lower explosion limit: 1,1 %(V)
Flash point: 74 °C - closed cup
Autoignition temperature: 207 °C at 1.013 hPa
Decomposition temperature: No data available

pH: No data available
Viscosity
Viscosity, kinematic: 4,55 mm2/s at 20 °C3,82 mm2/s at 25 °C
Viscosity, dynamic: No data available
Water: solubility soluble
Dilution Ratio: SBP 100/140 0.8
Heat of Vaporization @ Tboil: 306 kJ/kg
Miscibility @ 20°C: Solvent in water, complete
Azeotrope with Water: Boiling Point 99.2 °C
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 203.28 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.068000 mmHg @ 25.00 °C. (est)
Flash Point: 170.00 °F. TCC ( 76.70 °C. ) (est)
logP (o/w): -0.223 (est)
Formula: CH3O[CH2CH(CH­3)O]2H

CAS No: 34590-94-8
Molar mass: 148.2 g mol-1
Density: 0.951 g/cm, liquid
Boiling Point: 190 C
Viscosity: 3.7 cP at 25 C
Evaporation Rate (n-butyl acetate=1): 0.035
Melting point: -80°C
Boiling point: 90-91 °C at 12 mm Hg (lit.)
Density: 0.954 g/mL at 20 °C (lit.)
Vapor pressure: 0.4 mm Hg (25 °C)
Refractive index: n20/D 1.422
Flash point: 166 °F
Storage temperature: Store below +30°C
Water Solubility: Completely miscible in water
Solubility: Chloroform (Slightly), Methanol (Slightly)
Form: Colorless liquid
Color: Colorless to Almost colorless

pH: 6-7 (200g/l, H2O, 20℃)
Explosive limit: 1.1-14% (V)
Viscosity: 4.55 mm2/s
Merck: 14,3344
Stability: Stable
InChIKey: QCAHUFWKIQLBNB-UHFFFAOYSA-N
LogP: 0.004 at 25℃
CAS DataBase Reference: 34590-94-8
Indirect Additives used in Food Contact Substances: DIPROPYLENE GLYCOL MONOMETHYL ETHER
FDA 21 CFR: 175.105
FDA UNII: RQ1X8FMQ9N
NIST Chemistry Reference: Dipropylene glycol monomethyl ether (34590-94-8)
EPA Substance Registry System: Dipropylene glycol monomethyl ether (34590-94-8)
Chemical formula: C7H16O3
Molar mass: 148.202 g/mol
Density: 0.951 g/cm3

Boiling point: 190 °C (374 °F; 463 K)
Solubility in water: Miscible
Partition coefficient: n-octanol/water log Pow: 0,004 at 25 °C
Vapor pressure: 0,5 hPa at 25 °C
Density: 0,951 g/cm3 at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Surface tension: 68,7 mN/m at 20 °C
Molecular Formula / Molecular Weight: C7H16O3 = 148.20
Physical State (20 deg.C): Liquid
CAS RN: 34590-94-8
PubChem Substance ID: 87567626
SDBS (AIST Spectral DB): 7945
Merck Index (14): 3344

MDL Number: MFCD00059604
CAS number: 34590-94-8
EC number: 252-104-2
Hill Formula: C₇H₁₆O₃
Chemical formula: (CH₃O)C₃H₆OC₃H₆(OH)
Molar Mass: 148.2 g/mol
HS Code: 2909 49 80
Boiling point: 184 °C (1013 hPa)
Density: 0.95 g/cm3 (20 °C)
Explosion limit: 1.1 - 14 %(V)
Flash point: 75 °C
Ignition temperature: 205 °C DIN 51794
Melting Point: -83 °C
pH value: 6 - 7 (200 g/l, H₂O, 20 °C)
Vapor pressure: 0.75 hPa (25 °C)
Formula: CH3O[CH2CH(CH­3)O]2H
CAS No: 34590-94-8

Molar mass: 148.2 g mol-1
Density: 0.951 g/cm, liquid
Boiling Point: 190 C
Viscosity: 3.7 cP at 25 C
Evaporation Rate (n-butyl acetate=1): 0.035
Boiling point: 408°F
Molecular weight: 148.2
Freezing point/melting point: -112°F
Vapor pressure: 0.5 mmHg
Flash point: 166°F
Vapor density: 5.11
Specific gravity: 0.95
Ionization: potential
Lower explosive limit (LEL): 1.1% at 392°F
Upper explosive limit (UEL): 3%
Temperature Limits for Antoine Equation: +50 to +190 °C
Refractive Index @ 20°C: 1.423

Thermal Conductivity @ 20°C: 0.11 W/m/°C
Color: Upper Explosion Limit: 8.7% v/v
Miscibility @ 20°C: Water in solvent, complete
Molecular weight: 148 g/mol
Water: 0.05% m/m
Density @ 20°C: 0.953 kg/L
Coefficient of Cubic Expansion @ 20°C: 10 x 10^-4/°C
Boiling Point: 191 °C
Antoine Constant A #: 6.70707 kPa, °C
Antoine Constant B #: 1633.03 kPa, °C
Vapour Pressure @ 20°C: Flash Point (Abel): 79 °C
Lower Explosion Limit: 1.3% v/v
Dielectric Constant @ 20°C: 10.5
Freezing Point: -83 °C
Viscosity @ 20°C: 4.3 mPa.s
Hydrogen Bonding Index: 0.0

Fractional Polarity: 0.050
Dilution Ratio: Toluene 4.2
Heat of Combustion (Net) @ 25°C: 27500 kJ/kg
Specific Heat @ 20°C: 2.0 kJ/kg/°C
Azeotrope with water: Solvent Content 8.0 % m/m
Relative Evaporation Rate (Ether=1): 360
Saturated Vapour Concentration @ 20°C: Hildebrand Solubility Parameter: 8.7 (cal/cm^3)^1/2
Purity: 98.5% m/m min
Relative Evaporation Rate (nBuAc=1): 0.04
Antoine Constant C #: 161.693 kPa, °C
Vapor Pressure @ 50°C: 0.10 kPa
Auto Ignition Temp: 205 °C
Electrical Conductivity @ 20°C: 10 uS/m
Surface Tension @ 20°C: 29 mN/m

NFPA health rating: 2
NFPA fire rating: 2
NFPA reactivity rating: 0
Melting Point: -80.0°C
Density: 0.9500g/mL
Boiling Point: 180.0°C
Flash Point: 75°C
Assay Percent Range: 98.5% min. sum of isomers (GC)
Packaging: Glass bottle
Linear Formula: CH3O(CH2)3O(CH2)3OH
Merck Index: 15, 3384
Specific Gravity: 0.95
Solubility Information: Solubility in water: soluble.
Other solubilities: miscible with benzene
Viscosity: 4 mPa.s (25°C)
Formula Weight: 148.2
Formula: C7H16O3
Formula mass: 148.20
Melting point, °C: -80
Boiling point, °C: 190

Vapor pressure, mmHg: 0.4 (25 C)
Vapor density (air=1): 5.11
Saturation Concentration: 0.05% (500 ppm) at 25 C (calculated)
Evaporization number: 0.02 (butyl acetate = 1)
Density: 0.951 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 3.5 cp @ 25C
Surface tension: 28.8 g/s2
Refractive index: 1.419 (25 C)
Chemical Formula: C7H16O2
Spec. No: PR/DPM/17/07-01
CAS NO.: 34590-94-8
UN No.: - (non-hazardous for transport)
Molecular Weight: 148.2g/mol
Appearance: clear colourless liquid
Purity (%): 99.0 min
Acidity (%): 0.02 max
Color (Pt-Co): 15 max
Distillation range (℃): 180-195
Specific gravity at 20(℃): 0.945-0.950



FIRST AID MEASURES of DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
-Description of first-aid measures:
*General advice:
Consult a physician.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
-Further information:
Use water spray to cool unopened containers.



EXPOSURE CONTROLS/PERSONAL PROTECTION of DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 30 min
*Body Protection:
Impervious clothing
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.



HANDLING and STORAGE of DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
-Precautions for safe handling:
*Advice on safe handling:
No smoking.
Take measures to prevent the build up of electrostatic charge.
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place



STABILITY and REACTIVITY of DIPROPYLENE GLYCOL METHYL ETHER (DPGME):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.


DIPROPYLENE GLYCOL MONOBUTYL ETHER (SOLVENON DPNB)
Methoxy Propoxy Propanol; DPG; Dipropylene Glycol Methyl Ether; Methoxypropoxypropanol; Mixture of Methyldipropylene glycol; Oxybispropanol, Methyl Ether; Bis-(2-Methoxypropyl) ether cas no:34590-94-8
DIPROPYLENE GLYCOL MONOMETHYL ETHER (SOLVENON DPM)
DIPROPYLENE GLYCOL; Oxybispropanol; Di-sec-alcohol; Bis(2-hydroxy-propyl)ether; CAS NO: 25265-71-8
DIPROPYLENE GLYCOL N-BUTYL ETHER
CAS Number: 29911-28-2
EC Number : 249-951-5
Molecular Weight: 190.28294000
Formula: C10 H22 O3

DESCRIPTION:
Dipropylene glycol n-butyl ether is a colourless liquid with a mild odour and low volatility.
Dipropylene glycol n-butyl ether has low water solubility, good coupling and demonstrates good solvency for coating resins.
Dipropylene glycol n-butyl ether is ideal for use in coatings, inks, textiles, cleaners, agricultural products, and adhesives.

Dipropylene glycol n-butyl ether is a cleaning agent that can also be found in cosmetics such as facial soaps because of its ability to dissolve dirt and other substances and to retain moisture.
It’s particularly good at removing soap scum, mold and mildew stains.
Like its sister ingredient Dipropylene Glycol Propyl Ether, it works by loosening the scum or stain from a surface.
Dipropylene glycol n-butyl ether is readily biodegradable, and is unlikely to bioaccumulate in the environmental food chains.
Additionally, Dipropylene Glycol Butyl Ether is less toxic to aquatic organisms than many alternatives.

Dipropylene Glycol Butyl Ether Acts as a coupling agent, solvent and coalescent.
Dipropylene Glycol Butyl Ether can promote and establish a stronger bond at the resin matrix/reinforcement interface.
Dipropylene Glycol Butyl Ether is Used in water-reducible coatings, water-borne latex coatings, solvent-based coatings and paint removers.


USES OF DIPROPYLENE GLYCOL N-BUTYL ETHER:
Dipropylene glycol n-butyl ether is used in surface coatings, leather, pesticides, electrical, industrial cleaners, resins, and printing inks.
Dipropylene glycol n-butyl ether is Used as a coupling agent (degreasers, paint removers, metal cleaners, and hard surface cleaners), coalescent (latex coatings), solvent (water-reducible coatings), and chemical intermediate (epoxides, acid ester derivatives, solvents, and plasticizers)



CHEMICAL AND PHYSICAL PROPERTIES OF DIPROPYLENE GLYCOL N-BUTYL ETHER:
Description: Liquid;COLOURLESS LIQUID
IUPAC Name: 1-(1-butoxypropan-2-yloxy)propan-2-ol
Category: Biomaterials
Molecular Formula: C10H22O3;C10H22O3
Molecular Weight: 190.28g/mol
Rotatable Bond Count: 8
Exact Mass: 190.156895g/mol
Monoisotopic Mass: 190.156895g/mol
Heavy Atom Count:13
Formal Charge:0
Complexity:106
Covalently-Bonded Unit Count:1
Color/Form:Colorless liquid
Boiling Point:>200 °C;230 °C
Melting Point: None; turns to glass at -43 °C
Flash PointAPPROX 425 DEG (Open Cup);111 °C c.c.
H-Bond Donor:1
H-Bond Acceptor:3
Vapor Pressure:0.001 mm Hg at 30 °C;Vapor pressure, Pa at 20 °C: 6
Viscosity: 20 cSt at 20 °C /340 approximate molecular weight/
Refractive Index:
Index of refraction: 1.4400 at 20 °C/D
Decomposition: When heated to decomp it emits acrid smoke and irritating fumes.
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.91300 @ 25.00 °C.
Boiling Point: 261.65 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.002000 mmHg @ 25.00 °C. (est)
Flash Point: 205.00 °F. TCC ( 96.11 °C. )
logP (o/w): 1.306 (est)
Density: 0.91 g/cm3
Kinematic viscosity: 4.23 cSt
Surface tension : 28.2 mN/m
Density : 0.9100 g/mL
Melting Point: -75.0°C
Boiling Point: 230.0°C
Flash Point: 100°C
Quantity: 10 L
Solubility Information: Solubility aq. soln.: 40-45 g/L (25°C).
Specific Gravity: 0.91
Formula Weight: 190.28
Viscosity: 4.35 mPa.s (25°C)
Chemical Name or Material: Dipropylene glycol monobutyl ether
Physical State : Liquid
Color: Colorless
Odor: Ether
Flash Point - Closed Cup 100 °C (212 °F) Setaflash Closed Cup ASTMD3278
Flammability (solid, gas) No
Flammable Limits In Air Lower: 0.6 %(V) Literature
Upper: 20.4 %(V) Literature
Autoignition Temperature: 194 °C (381 °F) Literature
Vapor Pressure: < 0.04 mmHg @ 20 °C Literature
Boiling Point (760 mmHg): 230 °C (446 °F) Literature .
Vapor Density (air = 1): 6.60 Literature
Specific Gravity (H2O = 1) : 0.910 25 °C/25 °C Literature
Solubility in water (by weight): 4.5 % @ 25 °C Literature
Dynamic Viscosity: 4.9 mPa.s @ 25 °C Literature
Boiling point: 222-232 °C(lit.)
Density: 0.913 g/mL at 25 °C(lit.)
vapor pressure: 4Pa at 20℃
refractive index : n20/D 1.426(lit.)
Flash point: 205 °F
Pka: 14.41±0.20(Predicted)
Viscosity: 5.84mm2/s
Water Solubility: 40g/L at 25℃
Stability:
Stable, Combustible, Incompatible with strong oxidizing agents.
LogP: 1.52 at 20℃
Molecular Weight: 190.28
XLogP3-AA: 1.4
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 8
Exact Mass: 190.15689456
Monoisotopic Mass: 190.15689456
Topological Polar Surface Area: 38.7 Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 106
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes


SAFETY INFORMATION ABOUT DIPROPYLENE GLYCOL N-BUTYL ETHER:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

SYNONYMS OF DIPROPYLENE GLYCOL N-BUTYL ETHER:
DPNB
DIPROPYLENE GLYCOL MONOBUTYL ETHER
dowanol dpnb
Solvenon DPnB
BUTYL PROPASOL
DOWANOL(TM) DPNB
butyldipropasolsolvent
Dipropylene glycol mono-n-butyl ether
1-(2-butoxy-2-methylethoxy-2-propanol
1-(2-butoxy-1-methylethoxy)propan-2-ol
SCHEMBL15826
Dipropylene Glycol Normal Butyl Ether
2,5-Dimethyl-3,6-dioxadecane-1-ol
AKOS006320290
W-109216


DIPROPYLENE GLYCOL N-PROPYL ETHER
CAS no:29911-27-1
EC no:249-949-4
Substance name:Dipropylene glycol N-propyl ether
Trade name:Dipropylene glycol N-propyl ether
Formula:C9H20O3



DESCRIPTION:

Dipropylene Glycol n-Propyl Ether (DPnP) is a colorless liquid with an ether-like odor that evaporates slowly.
Dipropylene Glycol n-Propyl Ether is used as a solvent and as a coalescent for water-borne latex coatings.
Dipropylene Glycol n-Propyl Ether is a component of cleaning formulations and of household and personal care products from which occupational and consumer exposure is likely.

Dipropylene Glycol n-Propyl Ether is a clear, colorless having a mild characteristic odor.
The principal end uses of DPnB are industrial solvent, chemical intermediate, printing inks, paints and coatings
Glycol Ether DPnP solvent is a colorless liquid with low toxicity and a low odor.
Its low evaporation rate coupled with its hydrophilic and hydrophobic nature makes Glycol Ether DPnP a good coupling agent and solvent.
Dipropylene Glycol n-Propyl Ether is moderately water soluble, yet an efficient surface tension reduce.



CHEMICAL AND PHYSICAL PROPERTIES OF DIPROPYLENE GLYCOL N-PROPYL ETHER:
Assay: ≥98.5%
refractive index: n20/D 1.424 (lit.)
bp: 212 °C (lit.)
Density: 0.92 g/mL at 25 °C (lit.)
Molecular Weight: 176.3 g/mol
Empirical Formula :C9H20O3
Appearance: Colorless
Freezing Point -85°C (-121°F)
Flash Point – Closed Cup 94°C (201°F)
Boiling Point @ 760mmHg: 212°C (414°F)
Autoignition Temperature: 205°C (401°F)
Density @ 20°C:
0.921 kg/l
7.68 lb/gal
Vapor Pressure @ 20°C :0.1 mmHg
Evaporation Rate (nBuAc = 1) :0.014
Solubility @ 20°C (in Water) :15 wt%
Viscosity @ 25°C: 11.4 cP
Surface Tension @ 25°C: 27.8 mN/m
Lower Flammability in Air :0.68% v/v
Upper Flammability in Air: 8.3% v/v
Specific Heat @ 25°C :1.94 J/g/°C
Heat of Vaporization @ normal boiling point: 265 J/g
Heat of Combustion @ 25°C :29.7 kJ/g

Acidity, wt. % as
Acetic acid, max.: 0.015
Water, Wt. %, max. :0.2
Color, APHA, max.: 20
Purity, Wt. %, min.: 98.5
Specific Gravity @ 25/25°C: 0.915-0.925
Distillation @ 760 mm HG
IBP, Initial Boiling Point, °C
DP, Dry Point, °C
200-225
200-25



APPLICATIONS OF DIPROPYLENE GLYCOL N-PROPYL ETHER:
Coatings:
Dipropylene Glycol N-Propyl Ether performs well in coatings applications as a coalescent for waterborne coatings and a solvent for solvent-borne coatings.
Dipropylene Glycol N-Propyl Ether blends well with other materials such as the more hydrophobic glycol ethers.
Overall Dipropylene Glycol N-Propyl Ether makes an excellent choice as a coalescing agent and Dipropylene Glycol N-Propyl Ether makes a good viscosity control agent.
Cleaners:
Low toxicity, surface tension reduction, and moderate evaporation are some of the benefits of using Dipropylene Glycol N-Propyl Ether in cleaning formulations.
Dipropylene Glycol N-Propyl Ether also provides good solvency for polar and non- polar materials.
Other Applications:
The properties of Dipropylene Glycol N-Propyl Ether also support its use in agricultural, electronic, inks, textile, sealants and adhesive products.
Specific end uses may require approval from governing regulatory agencies.

Storage:
General industry practice is to store Dipropylene Glycol N-Propyl Ether in carbon steel vessels.
Avoid contact with air when storing for long periods of time.
Glycol ethers should never be stored or handled in copper or copper alloys.
This product may absorb water if exposed to air.

Store only in tightly closed, properly vented containers away from heat, sparks, open flame or strong oxidizing agents.
Use only non-sparking tools.
Ground containers before beginning transfer.
Electrical equipment should conform to national electric code.

Safety and Handling:
Due to its low order of toxicity, Dipropylene Glycol N-Propyl Ether requires no special handling.
However, undue exposure or spillage should be strictly avoided as a matter of good practice.

Occupational exposures:
Occupational exposures with Dipropylene Glycol N-Propyl Ether are usually via the dermal and/or inhalation route.

As a derivative of the propylene glycol-based ethers, DPnP is expected to present low order toxicity and pose little hazard under normal conditions of exposure and use.
As with many solvents, precautions to minimize skin and eye contact and repeated or prolonged inhalation to high vapor concentrations should be taken.


Material Compatibility Guidelines:
Stainless steel is recommended for valves, pumps and filters.

Teflon is suitable for gaskets.
Information from material suppliers and specific conditions of contact should be considered in the selection of suitable materials.



SAFETY INFORMATION ABOUT DIPROPYLENE GLYCOL N-PROPYL ETHER:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.




SYNONYMS OF DIPROPYLENE GLYCOL N-PROPYL ETHER:
DPNP
Arcosolv DPNP
ARCOSOLV(R) DPNP
propyldipropasolsolvent
5-Methyl-4,7-dioxadecane-2-ol
DI(PROPYLENE GLYCOL) PROPYL ETHER
Dipropylene glycol n-propyl ether
Dipropylene glycol monopropyl ether
Dipropylene glycol mono-n-propyl ether
Dipropylene glycol propyl ether
Dipropylene glycol propyl ether, mixt. of isomers
DPnP 2-Propanol, 1-(2-propoxy-1-methylethoxy)-
1-(2-Propoxy-1-methylethoxy)-2-propanol
Propyl dipropasol solvent


DIPROPYLENE GLYCOL PHENYL ETHER
Dipropylene Glycol Phenyl Ether
Cas: 104-68-7
Molecular Formula: C12-H18-O3



APPLICATIONS


Dipropylene Glycol Phenyl Ether is used as solvent for resins, lacquers, paints, varnishes, gum, perfume, dyes, inks, as a constituent of paints and pastes, cleaning compounds, liquid soaps, cosmetics, and hydraulic fluids.
Furthermore, Dipropylene Glycol Phenyl Ether is used in the production of cleaning agents and as a general solvent.

A major use of Dipropylene Glycol Phenyl Ether is as a solvent that facilitates the mixing of aqueous and organic constituents in paints, coatings, and films.
Dipropylene Glycol Phenyl Ether is used as a latex coalescent in water-based architectural and industrial coatings and adhesives, a carrier solvent for textile dyes, a solvent for inks in ball point and felt tip pens, stamp pads, and textile printing pastes, and paint remover.
Due to its antibacterial properties, Dipropylene Glycol Phenyl Ether also is used in cosmetics and soaps.

The primary use of Dipropylene Glycol Phenyl Ether is as a solvent that facilitates the mixing of
aqueous and organic constituents in paints, coatings, and films.
Dipropylene Glycol Phenyl Ether is used as a latex coalescent in water-based architectural and industrial coatings and adhesives, a carrier solvent for textile dyes, a solvent for inks in ball point and felt tip pens, stamp pads, and textile printing pastes, and a paint remover.
Due to its antibacterial properties, Dipropylene Glycol Phenyl Ether also is used in cosmetics and soaps.

The most significant exposure potential is by inhalation and dermal contact during application of paints and coatings, or application of materials for which Dipropylene Glycol Phenyl Ether is a carrier.
The types of products in which Dipropylene Glycol Phenyl Ether is used (and their percents of production), and the approximate concentrations of Dipropylene Glycol Phenyl Ether used in products are variable.

Cleaning by soil roll-up can be accomplished by Dipropylene Glycol Phenyl Ether.
The solvent must have a lower surface tension than the soil, and must be partially (not fully) soluble in the soil it is displacing.

Water-based cleaner formulations containing Dipropylene Glycol Phenyl Ether exhibit lower dynamic surface tensions than formulations containing traditional surfactants alone.
Dipropylene Glycol Phenyl Ether should have lower molecular weight than the surfactants.

Compared to high HLB Glycol Ethers, Dipropylene Glycol Phenyl Ether is highly effective in lowering dynamic surface tension.
In addition, Dipropylene Glycol Phenyl Ether reduces the surface tension of water efficiently even when considering their lower solubility limits.

Dipropylene Glycol Phenyl Ether is permitted for use as an inert ingredient in non-food pesticide products.
Moreover, Dipropylene Glycol Phenyl Ether is used as a solvent for paints, coatings, films, textile dyes and printing pastes, inks in ball point and felt tip pens, stamp pads, and paint removers, as a coalescent in water-based coatings and adhesives, and in cosmetics and soaps (possesses antibacterial properties).

Dipropylene Glycol Phenyl Ether is high-boiling solvent, bactericidal agent, fixative for soaps and perfumes, and intermediate for plasticizers.
Besides, Dipropylene Glycol Phenyl Ether is a useful synthetic intermediate.

Dipropylene Glycol Phenyl Ether was used in the preparation of acyl aryl thiocarbamates as nonnucleoside reverse transcriptase inhibitors.
In addition, Dipropylene Glycol Phenyl Ether is used extensively in dyeing applications, where it can function as both a dye solubilizer and as a dye carrier.

Dipropylene Glycol Phenyl Ether is latex coalescent in water-based architectural and industrial coatings.
Additionally, Dipropylene Glycol Phenyl Ether is solvent for inks in ball point and felt tip pens, stamp pads, and textile printing pastes.
Dipropylene Glycol Phenyl Ether can be used as paint removers.

Dipropylene Glycol Phenyl Ether is coalescent for latex adhesives.
More to that, Dipropylene Glycol Phenyl Ether is useful in the formulation of homogeneous, stable metalworking fluids.

Dipropylene Glycol Phenyl Ether is hydrophobic solvent in the cleaner partitions out of the water and into the soil.
This reduces the soil viscosity and surface tension with water.

This softening of the soil, which is a typical characteristic of Dipropylene Glycol Phenyl Ether in aqueous cleaners, allows for mechanical breakup.
Without this softening, removal would be impossible or very difficult.

Low HLB (Hydrophilic-Lipophilic Balance) glycol ethers worked as the most effective cleaner, typically Dipropylene Glycol Phenyl Ether, while high HLB glycol ethers worked as the least effective for heavy soils.

Dipropylene Glycol Phenyl Ether has excellent coupling ability.
Coupling is a method of compatibilizing a multiphase system that results in an increase in the degree of homogeneity of the system.

Dipropylene Glycol Phenyl Ether couples oil-soluble soil with water and, together with the surfactant, keeps the soil suspended in the cleaning solution to prevent it from being re-deposited on the cleaned surface.
Further to that, Dipropylene Glycol Phenyl Ether has very good evaporation rate flexibility.

Dipropylene Glycol Phenyl Ether offers a wide range of evaporation rates for formulation requirements.
Furthermore, Dipropylene Glycol Phenyl Ether is an excellent choic for a window cleaner that evaporates fast enough to prevent streaking.
Dipropylene Glycol Phenyl Ether does well in formulations such as grill and oven cleaners, where they provide the longer contact time necessary to thoroughly penetrate the heavy greasy oil and baked-on material.


Features of Dipropylene Glycol Phenyl Ether:

Coalescing ability
Powerful solvency
High dilution ratio
Low evaporation rate
Low viscosity
Storage stability


Suggested Applications of Dipropylene Glycol Phenyl Ether:

Latex coalescent in water-based architectural and industrial coatings.
Carrier solvent for textile dyes.
Solvent for inks in ball point and felt tip pens, stamp pads, and textile printing pastes.
Paint removers.
Coalescent for latex adhesives.
Useful in the formulation of homogeneous, stable metalworking fluids.


Uses of Dipropylene Glycol Phenyl Ether:

Products used to polish metal surfaces
Cleaning agent
Finishing agents
Ink Component
Lubricants and lubricant additives
Processing aids, not otherwise listed
Solvents (for cleaning and degreasing)
Solvents (which become part of product formulation or mixture)
Fabric, textile, and leather products not covered elsewhere
Floor coverings
Ink, toner, and colorant products
Lubricants and greases
Paints and coatings
Solvent
All Other Basic Organic Chemical Manufacturing
Paint and Coating Manufacturing
Cleaners: household and industrial cleaners
Textiles: dyes and printing pastes
Cosmetics
Resins
Coating formulation and application
Industrial, automotive and architectural coatings
Metal working fluids: surface cleaning and fabrication


Benefits of Dipropylene Glycol Phenyl Ether:

Favorable enviornmental profile, superior performance for end use applications, formulations may require less Performancesolvent than P or E Series
Low vapor pressure allowing formulations to meet volatile organic compound regulations
Readily biodegradable
U.S. EPA Inerts listed for non-food use
Excellent for soap scum and greasy soil removal


Other applications of Dipropylene Glycol Phenyl Ether:

Carrier solvent for textile dyes.
Coalescent for latex adhesives.
Useful in the formulation of homogeneous, stable metalworking fluids.



DESCRIPTION


Glycol ethers are a class of chemical compounds consisting of alkyl ethers that are based on glycols such as ethylene glycol or propylene glycol.
Dipropylene Glycol Phenyl Ether belongs to this group.

Dipropylene Glycol Phenyl Ether is commonly used as solvent in paints and cleaners.
Furthermore, Dipropylene Glycol Phenyl Ether has good solvent properties while having higher boiling points than the lower-molecular-weight ethers and alcohols.

Dipropylene Glycol Phenyl Ether is a fine chemical and a useful building block.
Moreover, Dipropylene Glycol Phenyl Ether is an important intermediate in the synthesis of other chemicals, such as pharmaceuticals, herbicides, and pesticides.

Dipropylene Glycol Phenyl Ether can be used as a research chemical or reagent.
Besides, Dipropylene Glycol Phenyl Ether can also be used to prepare complex compounds and versatile scaffolds.

Glycol ethers are a broad class of commodity chemicals that find use in numerous applications.
One member of this class is Dipropylene Glycol Phenyl Ether.

Dipropylene Glycol Phenyl Ether is commonly used as ingredients in paints and coatings, cleaning products, and personal care products.
In addition, Dipropylene Glycol Phenyl Ether is produced and used in enormous quantities, primarily in Western Europe, China, and the United States.

The unique amphiphilic structure of Dipropylene Glycol Phenyl Ether provides favorable properties such as low volatility, strong solvent strength, high water solubility, and the ability to serve as coupling agents that promote the miscibility of aqueous and organic phases.
These properties make Dipropylene Glycol Phenyl Ether a popular alternative to traditional oxygenated solvents such as ketones, ethers, and alcohols.

Dipropylene Glycol Phenyl Ether is a slow evaporating, very hydrophobic glycol ether — more hydrophobic than would be expected based simply on its molecular weight.
Additionally, Dipropylene Glycol Phenyl Ether has low odor.

With its aromatic structure, Dipropylene Glycol Phenyl Ether is an excellent match for phenolic coatings and linings.
Dipropylene Glycol Phenyl Ether is also an excellent coalescent for acrylic-based latexes.

Dipropylene Glycol Phenyl Ether is also used extensively in dyeing applications, where it can function as both a dye solubilizer and as a dye carrier.
More to that, Dipropylene Glycol Phenyl Ether has superior viscosity reduction properties in metalworking fluids.



PROPERTIES


Molecular Weight: 182.22
XLogP3: 1
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 6
Exact Mass: 182.094294304
Monoisotopic Mass: 182.094294304
Topological Polar Surface Area: 38.7 Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 111
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID


Eye Contact:

May cause severe eye irritation.
May cause slight corneal injury.
Immediately flush eyes with water.

Remove contact lenses, if present, after the first 5 minutes, then continue flushing eyes for at least 15 minutes.
Obtain medical attention without delay, preferably from an ophthalmologist.
Eye wash fountain should be located in immediate work area.


Skin Contact:

Prolonged contact may cause slight skin irritation with local redness.
Wash skin with plenty of water.


Skin Absorption:

Prolonged skin contact is unlikely to result in absorption of harmful amounts.


Inhalation:

At room temperature, vapors are minimal due to low volatility.
Vapor from heated material or mist may be hazardous on single exposure.
Move person to fresh air; if effects occur, consult a physician.


Ingestion:

Low toxicity if swallowed.
Small amounts swallowed incidentally as a result of normal handling operations are not likely to cause injury; however, swallowing larger amounts may cause injury.
If swallowed, seek medical attention.
Do not induce vomiting unless directed to do so by medical personnel.


Notes to Physician:
Maintain adequate ventilation and oxygenation of the patient.
No specific antidote.
Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.


Emergency Personnel Protection:

First Aid responders should pay attention to self-protection and use the recommended protective clothing (chemical resistant gloves, splash protection).
If potential for exposure exists refer to specific personal protective equipment.



HANDLING AND STORAGE


Handling:


General Handling:

Avoid contact with eyes.
Wash thoroughly after handling.


Other Precautions:

Spills of these organic materials on hot fibrous insulations may lead to lowering of the autoignition temperatures possibly resulting in spontaneous combustion.


Storage:

Store in the following material(s): Carbon steel. Stainless steel. Phenolic lined steel drums.
Do not store in: Aluminum. Copper. Galvanized iron. Galvanized steel.



SYNONYMS


(Methyl-2-Phenoxyethoxy)Propanol
1-(1-Methyl-2-Propoxyethoxy)Propan-2-ol
2-Propanol, 1-(1-Methyl-2-Propoxyethoxy)-
Dipropylene Glycol Monopropyl Ether
Polyoxypropylene (2) Propyl Ether
Polypropylene Glycol (2) Propyl Ether
PPG-2 Propyl Ether (INCI)
Propanol, (Methyl-2-Phenoxyethoxy)
Propanol, (Methyl-2-Propoxyethoxy)-
Propanol, 1(or 2)-(Methyl-2-Phenoxyethoxy)-
Propanol, 1-(Methyl-2-Phenoxyethoxy)-
Propoxy Dipropylene Glycol
diethylene glycol phenyl ether
diethylene glycolphenyl ether
ethanol, 2-(2-phenoxyethoxy)-
phenoxydiglycol
2-(2-phenoxyethoxy)ethan-1-ol
2-(2-phenoxyethoxy)ethanol
phenyl carbitol
2-(2-Phenoxyethoxy)ethanol
104-68-7
Diethylene glycol monophenyl ether
Phenyl carbitol
ETHANOL, 2-(2-PHENOXYETHOXY)-
Phenoxydiglycol
Diethylene glycol phenyl ether
Fenylkarbitol
2-(2-phenoxyethoxy)ethan-1-ol
Diethylene glycolphenyl ether
LZU6ET206Z
diethyleneglycol monophenyl ether
NSC-406593
Fenylkarbitol [Czech]
Ethanol,2-(2-phenoxyethoxy)-
EINECS 203-227-5
UNII-LZU6ET206Z
NSC 406593
BRN 2093125
phenyl diglycol
Ethanol, 2-(2-phenoxyethoxy)-
2-(2-Phenoxyethoxy)ethanol
Phenyl carbitol
Diethylene glycol monophenyl ether
Phenoxydiglycol
Diethylene glycol phenyl ether
Sunfine PH 20
NSC 406593
Phenyl Di Glycol
PhDG
2-(2-Phenoxyethoxy)ethan-1-ol
AI3-04321
PHENYL DI GLYCOL
EC 203-227-5
WLN: Q2O2OR
SCHEMBL24035
DTXSID0051528
ZINC1599304
MFCD00045989
NSC406593
AKOS008145660
AS-41733
CS-0217586
fenylkarbitol
phenyl carbitol
2-(2-phenoxyethoxy)ethanol
2-(2-phenoxyethoxy)-ethano
Ethanol, 2-(2-phenoxyethoxy)-
2-(2-Phenoxyethoxy)ethan-1-ol
Diethylene glycol phenyl ether
[2-(2-Hydroxyethoxy)ethoxy]benzene
D5139
FT-0696890
EN300-78435
W-109056
Q27283278
Z756092452
DIPROPYLENE GLYKOL
dipropylene triamine 1,3-propanediamine, N1-(3-aminopropyl); imino-bis (3-propylamine); 1- propanamine, 3,3'-iminobis- cas no:56-18-8
DIPROPYLENETRIAMINE-BAXXODUR EC110
DISODIUM 2-SULFOLAURATE, N° CAS : 38841-48-4, Nom INCI : DISODIUM 2-SULFOLAURATE, Nom chimique : Disodium 2-sulfododecanoate. Ses fonctions (INCI) : Agent nettoyant : Aide à garder une surface propre. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISFLAMOLL 51036
Disflamoll 51036 is a flame retardant low viscosity phosphate ester blend with the following benefit in flexible PVC: very good plasticizing efficiency, fast gelling and good flexibility at low temperatures.
Disflamoll 51036 is recommended for the use in flexible PVC applications, especially for artificial leather, whenever flame retardance is required in combination with good low temperature performance.
Disflamoll 51036 is a phosphate ester preparation.

CAS: 26444-49-5
MF: C19H17O4P
MW: 340.31
EINECS: 247-693-8

Synonyms
Cresyl Diphenyl Phosphate (so called) (mixture of analogue);Zinc02041271;Diphenyltolylphosphate - Mixture of o-,m-,p-tolyl isomers;Diphenyl Methylphenyl phosphate, Mixture of isoMers, 94%;2-Methylphenyl diphenyl phosphate;Cresyl phenyl phosphate;cresyldiphenylphosphate(cdpmixedisomers);Diphenyl tolyl ester phosphoric acid

Acts as a low viscosity phosphate ester plasticizer with fast gelling in flexible PVC and good flexibility at low temperatures.
Disflamoll 51036 also acts as a flame retardant.
Compatible with PVC.
Disflamoll 51036 has a minimum shelf life of 1 year.
Probably seldom a pure compound, but a mixture of o-, m-, and p-cresyl and phenyl phosphates.
A clear transparent liquid with a very slight odor.
Insoluble in water.
Primary hazard is to the environment.
Immediate steps should be taken to limit spread to the environment.
Easily penetrates the soil to contaminate groundwater and nearby waterways.

Disflamoll 51036 Chemical Properties
Melting point: -38°C
Boiling point: 235-255°C
Density: 1.20
Fp: 232°C
Refractive index: 1.5630
Storage temp.: Sealed in dry,Room Temperature
Form: Liquid
Specific Gravity: 1.21
Color: Pale yellow
InChIKey: OJUZRFGUKHQNJX-UHFFFAOYSA-N
LogP: 4.510
CAS DataBase Reference: 26444-49-5(CAS DataBase Reference)
NIST Chemistry Reference: Disflamoll 51036 (26444-49-5)
EPA Substance Registry System: Disflamoll 51036 (26444-49-5)

Uses
Plasticizer, extreme-pressure lubricant, hydraulic fluids, gasoline additive, food packaging.

Health Hazard
Inhalation of material may be harmful.
Contact may cause burns to skin and eyes.
Inhalation of Asbestos dust may have a damaging effect on the lungs.
Fire may produce irritating, corrosive and/or toxic gases.
Some liquids produce vapors that may cause dizziness or suffocation.
Runoff from fire control may cause pollution.
DISFLAMOLL 51092
Disflamoll 51092 is mostly used as a plasticizing flame retardant in flexible PVC.
Disflamoll 51092 enables high material strength.
Disflamoll 51092 can also be used as a flame retardant for polyurethanes (TPU), elastomeres and thermosets.

CAS: 68937-40-6
MF: C30H39O4P
MW: 494.6
EINECS: 273-065-8

Synonyms
Einecs 273-065-8;Isobutylenated phenol phosphate (3:1);Phenol, isobutylenated, phosphate (3:1);DURAD220B;DURADMP280B;ISOBUTYLENATEDPHENOL,PHOSPHATE;Phenol, isobutyleniert, Phosphat ;(3:1);tris(isobutylphenyl)phosphate;Phenol, isobutylenated, phosphate (3:1);68937-40-6;tris[4-(2-methylpropyl)phenyl] phosphate;Durad 220B;Triisobutylenated triphenylphosphate;Isobutylenated phenol phosphate (3:1);68759-64-8;XPE77R3GK8;tris(4-isobutylphenyl) phosphate;Durad 550B;EINECS 273-065-8;UNII-XPE77R3GK8;Isobutylenated phenol phosphate;SCHEMBL1791289;DTXSID40867770;LWYPBQJBRGDLOI-UHFFFAOYSA-N;4-(2-Methylpropyl)-phenolPhosphate;Q27293953;tris[4-(2-methylpropyl)phenyl] phosphate; Durad 220B; Triisobutylenated triphenylphosphate; ;Isobutylenated phenol phosphate (3:1); Durad 550; Isobutylenated phenol phosphate

Disflamoll 51092 is not compatible with completely nonpolar polymers such as polyethylene or polypropylene.
Disflamoll 51092 is a butylated triphenyl phosphate-based flame retardant.
Disflamoll 51092 is a phosphate ester with good plasticizing efficiency in many polymers.
Disflamoll 51092 is a halogen-free additive and exhibits low odor.
Disflamoll 51092 finds application in tarpaulins, cables, E&E housings, furniture and automotive interiors to thermos insulated hoses.
Disflamoll 51092 is also used in many plastics (plasticized PVC, flexible PU foams, TPU, PC-ABS and NBR-PVC blends), coated textile fiber, flexible PVC, polyurethanes and elastomers.
Disflamoll 51092 has a shelf life of 2 years.

Disflamoll 51092 is a synthetic additive for lubricating oils.
Disflamoll 51092 has been shown to be resistant to oxidation and photochemical degradation.
Disflamoll 51092 also has the ability to absorb UV radiation from sunlight and protect the photoreceptor layer of the eye from damage.
Disflamoll 51092 has a viscosity index that is 16 times higher than that of petroleum ethers.
The phenolic nature of Disflamoll 51092 makes it an excellent anti-wear additive for automotive engines and other heavy machinery.
Disflamoll 51092, also known as Durad 150B, is a synthetic butyl phenyl phosphate.
Disflamoll 51092 is classified in the lubricant industry as a triaryl phosphate.

Synthesis Analysis
Disflamoll 51092 is made by the reaction of phenol with propylene.
The resulting product is a mixture of mainly ortho- and para-isomers with varying degrees of alkylation.
Disflamoll 51092 of this reaction is then mixed with phenol and reacted with phosphorus oxychloride to produce the phosphate ester .
DISFLAMOLL DPK
Disflamoll DPK is mostly used as a plasticizing flame retardant in flexible PVC.
Disflamoll DPK can also be used as a flame retardant for polyurethanes (TPU), elastomers and thermosets such as phenolic resin for printed circuit boards.
Disflamoll DPK is not compatible with completely nonpolar polymers such as polyethylene or polypropylene.

CAS: 26444-49-5
MF: C19H17O4P
MW: 340.31
EINECS: 247-693-8

Synonyms:
Cresyl Diphenyl Phosphate (so called) (mixture of analogue);Zinc02041271;Diphenyltolylphosphate - Mixture of o-,m-,p-tolyl isomers;Diphenyl Methylphenyl phosphate, Mixture of isoMers, 94%;2-Methylphenyl diphenyl phosphate;Cresyl phenyl phosphate;cresyldiphenylphosphate(cdpmixedisomers);Diphenyl tolyl ester phosphoric acid;Diphenyl p-tolyl phosphate;78-31-9;p-Cresyl diphenyl phosphate.;(4-methylphenyl) diphenyl phosphate;Diphenyl 4-tolyl phosphate;Phosphoric acid, 4-methylphenyl diphenyl ester;X0UF1XXO1Q;Phosphoric acid, diphenyl p-tolyl ester;UNII-X0UF1XXO1Q;HSDB 2558;P-CRESYL DIPHENYL PHOSPHATE;EINECS 201-104-0;Diphenyl4-tolylphosphate;DSSTox_CID_4861;Monotolyl diphenyl phosphate;DSSTox_RID_77555;DSSTox_GSID_24861;SCHEMBL35597;CHEMBL3187626;DTXSID70274039;4-Methylphenyl diphenyl phosphate #;Tox21_202888;AKOS015899069;NCGC00260434-01;1ST22669;P-CRESYL DIPHENYL PHOSPHATE [HSDB];CAS-26444-49-5;DB-351173;NS00076535;Cresyl diphenyl phosphate (mixture of analogue);F88144;Diphenyl p-tolyl phosphate (mixture of analogue);PHENYL P-TOLYL PHOSPHATE ((PHO)2(C7H7O)PO);Q27293237

Probably seldom a pure compound, but a mixture of o-, m-, and p-cresyl and phenyl phosphates.
A clear transparent liquid with a very slight odor.
Insoluble in water.
Primary hazard is to the environment.
Immediate steps should be taken to limit spread to the environment.
Easily penetrates the soil to contaminate groundwater and nearby waterways.
Disflamoll DPK by Lanxess is cresyl diphenyl phosphate (CDP).
Acts as a highly effective flame retardant phosphate ester.
Disflamoll DPK's flame retarding efficiency permits blending with standard plasticizers and so allowing wide flexibility for formulators.
Compatible with PVC, phenolic resins and epoxy resins, PC/ABS blends, TPU compounds, PUR- foams (rigid and flexible) and rubbers.
Disflamoll DPK has a minimum shelf life of 2 years.
Disflamoll DPK is a highly effective flame retardant phosphate ester for PVC and other polymers.

Disflamoll DPK Chemical Properties
Melting point: -38°C
Boiling point: 235-255°C
Density: 1.20
Fp: 232°C
Refractive index: 1.5630
Storage temp.: Sealed in dry,Room Temperature
Form: Liquid
Specific Gravity: 1.21
Color: Pale yellow
InChIKey: OJUZRFGUKHQNJX-UHFFFAOYSA-N
LogP: 4.510
CAS DataBase Reference: 26444-49-5(CAS DataBase Reference)
NIST Chemistry Reference: Disflamoll DPK (26444-49-5)
EPA Substance Registry System: Disflamoll DPK (26444-49-5)

Colorless, transparent liquid; very slight odor.
Insoluble in water; soluble in most organic solvents except glycerol.
Combustible.

Uses
Plasticizer, extreme-pressure lubricant, hydraulic fluids, gasoline additive, food packaging.
Disflamoll DPK is a flame retardant plasticizer with good compatibility with resin.
Disflamoll DPK is used for polyvinyl acetal, cellulose nitrate, polyvinyl chloride, natural rubber and synthetic rubber, etc.
Disflamoll DPK can also be used for synthetic lubricating oil and hydraulic oil.
Disflamoll DPK is a substitute for triphenyl phosphate.
Suitable for polyvinyl chloride, vinyl chloride copolymer, polyvinyl acetal, cellulose nitrate, ethyl cellulose, cellulose acetate butyrate, etc.

Reactivity Profile
Organophosphates, such as Disflamoll DPK, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides.
Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Health Hazard
Inhalation of material may be harmful.
Contact may cause burns to skin and eyes.
Inhalation of Asbestos dust may have a damaging effect on the lungs.
Fire may produce irritating, corrosive and/or toxic gases.
Some liquids produce vapors that may cause dizziness or suffocation.
Runoff from fire control may cause pollution.

Purification Methods
Distil Disflamoll DPK in a vacuum, then percolate it through a column of alumina.
Finally, pass Disflamoll DPK through a packed column maintained at 150o to remove traces of volatile impurities in a countercurrent stream of nitrogen under reduced pressure.
DISFLAMOLL DPO
Disflamoll DPO can be used as a flame retardant, an additive or a plasticizer for resins.
Disflamoll DPO is considered as an emerging contaminant.
Disflamoll DPO is an aryl phosphate.

CAS: 1241-94-7
MF: C20H27O4P
MW: 362.4
EINECS: 214-987-2

Synonyms
2-ETHYLHEXYL DIPHENYL PHOSPHATE;Diphenyl-2-ethylhexyl phosphate;OCTYL DIPHENYL PHOSPHATE;PHOSPHORIC ACID OCTYL DIPHENYL ESTER;PHOSPHORIC ACID DIPHENYL 2-ETHYLHEXYL ESTER;PHOSPHORIC ACID 2-ETHYLHEXYL DIPHENYL ESTER;(2-Ethylhexyl)-difenylfosfat;1-Hexanol, 2;ethyl-, ester with diphenyl phosphate;2-Ethylhexyl diphenyl phosphate;1241-94-7;Octicizer;Phosphoric acid, 2-ethylhexyl diphenyl ester;Santicizer 141;Octicizer [USAN];2-Ethylhexyldiphenylphosphate;(2-Ethylhexyl)-difenylfosfat;Diphenyl 2-ethylhexyl phosphate;Phosphoric acid diphenyl 2-ethylhexyl ester;1-Hexanol, 2-ethyl-, ester with diphenyl phosphate;4F53Z6NE1Y;DTXSID1025300;Octicizer (USAN);2-Ethylhexyl Diphenyl Phosphate (90%);2-Ethylhexyl diphenylphosphate;DIPHENYL-2-ETHYLHEXYL PHOSPHATE;EHDPHP;CCRIS 6199;HSDB 370;EINECS 214-987-2;(2-Ethylhexyl)-difenylfosfat [Czech];BRN 2568983;UNII-4F53Z6NE1Y;AI3-16360;di(2-ethylhexyl)phenylphosphate;Phosphoric Acid 2-Ethylhexyl Diphenyl Ester;Ethylhexyl diphenyl phosphate, 2-;Phosflex 362;Phosphoric Acid Octyl Diphenyl Ester;OCTICIZER [HSDB];2-Ethylhexyl diphenyl phosphate (technical);EC 214-987-2;(+/-)-OCTICIZER;SCHEMBL93483;4-06-00-00718 (Beilstein Handbook Reference);DTXCID105300;CHEMBL2105213;CGSLYBDCEGBZCG-UHFFFAOYSA-;CHEBI:188855;Tox21_303313;MFCD00059949;2-Ethylhexyl diphenyl phosphate (technical) 100 microg/mL in Acetonitrile;AKOS015889797;NCGC00257002-01;AS-15838;DA-16836;CAS-1241-94-7;2-Ethylhexyl diphenyl ester phosphoric acid;NS0001002;P1021;2-Ethylhexyl Diphenyl Phosphate (90per cent);2-Ethylhexyl diphenyl ester of phosphoric acid;D05224;D78379;2-Ethyl-1-hexanol ester with diphenyl phosphate;A805209;W-108410;Q27259513;2-Ethylhexyl diphenyl phosphate, PESTANAL(R), analytical standard;InChI=1/C20H27O4P/c1-3-5-12-18(4-2)17-22-25(21,23-19-13-8-6-9-14-19)24-20-15-10-7-11-16-20/h6;11,13-16,18H,3-5,12,17H2,1-2H3

Disflamoll DPO is an organophosphate compound.
Disflamoll DPO acts as both a plasticizer and flame retardant in PVC, its wide liquid range also makes it suitable as a flame retardant in hydraulic fluids.
Disflamoll DPO has low acute toxicity in feeding experiments, but has been implicated as a potential hormone mimetic.
Disflamoll DPO is a plasticizer, flame retardant, and a main component of non-flammable hydraulic fluids.
Disflamoll DPO has low acute toxicity in feeding experiments, but has been implicated as a potential hormone mimetic.
Disflamoll DPO by Lanxess is 2-ethylhexyl diphenyl phosphate (DPO).
Acts as a low viscosity phosphate ester plasticizer with good gelling behaviour for flexible PVC.
Disflamoll DPO acts also as a flame retardant in TPU, NBR and cellulose acetate.
Disflamoll DPO is fast fusing, has low viscosity plastisols, low temperature properties.
Disflamoll DPO can be recommended in certain food contact applications.
Disflamoll DPO has a minimum shelf life of 2 years.
Disflamoll DPO is a low viscosity phosphate ester plasticizer with good gelling behaviour in flexible PVC.
Disflamoll DPO acts also as a flame retardant in TPU, NBR and cellulose acetate.

Disflamoll DPO Chemical Properties
Melting point: -54°C
Boiling point: 375°C
Density: 1,09 g/cm3
Pour Point: -54
Vapor pressure: 26.7Pa at 150℃
Refractive index: 1.5080 to 1.5110
Fp: 224 °C
Storage temp.: 2-8°C
Solubility: Chloroform (Slightly), Methanol (Slightly)
Form: Liquid
Color: Colourless
Water Solubility: Insoluble
InChIKey: CGSLYBDCEGBZCG-UHFFFAOYSA-N
LogP: 5.87 at 25℃
CAS DataBase Reference: 1241-94-7(CAS DataBase Reference)
NIST Chemistry Reference: Disflamoll DPO (1241-94-7)
EPA Substance Registry System: Disflamoll DPO (1241-94-7)

Reactivity Profile
Organophosphates, such as Disflamoll DPO, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides.
Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Toxicology
Disflamoll DPO has only a very low acute toxicity (LD50, oral, rat and rabbit, more than 24 000 mg/kg).
No indications of carcinogenic effects were found in rats after two years of administration of the substance in the feed (up to 1%).
Disflamoll DPO was not genotoxic in the Ames test, the HGPRT test, and the in vivo chromosome aberration test in rats.
No teratogenic effects were observed in rats, and development of the offspring was only impaired at maternally toxic doses.
DISFLAMOLL TOF
Disflamoll TOF is a slightly flame retardant phosphate plasticizer offering excellent low temperature properties as well as good resistance to weathering.
Disflamoll TOF is suitable for the use in many types of polymers including flexible PVC, PUR, NBR, SBR and EPDM.
Disflamoll TOF is a strong, moderately polar solvent.

CAS: 78-42-2
MF: C24H51O4P
MW: 434.63
EINECS: 201-116-6

Synonyms
PHOSPHORIC ACID TRIS(2-ETHYLHEXYL) ESTER;PHOSPHORIC ACID TRIOCTYL ESTER;TRIS(2-ETHYLHEXYL) PHOSPHATE;TRI(2-ETHYLHEXYL)PHOSPHATE;TRIOCTYL PHOSPHATE;'TRIOCTYL' PHOSPHATE;1-Hexanol, 2-Ethyl-, phosphate;2-ethyl-1-hexanophosphate

Disflamoll TOF is therefore also used in a variety of non-plastic applications, such as a solvent in the production of hydrogen peroxide, a carrier for pigments in the manufacture of pigment pastes for plastics , an additive for lubricant applications and an adjuvant in herbicides.
Disflamoll TOF is a trialkyl phosphate.
Clear colorless to pale yellow liquid with a slight sharp odor.
Insoluble in water; Soluble in alcohol, acetone, and ether.
Combustible.
Disflamoll TOF is a phosphate ester plasticizer which imparts outstanding low-temperature flexibility and good resistance to weathering.
Disflamoll TOF is a strong, moderately polar solvent.
Disflamoll TOF by Lanxess is tris (2-ethylhexyl) phosphate (TOP).
Acts as a plasticizer.
Disflamoll TOF is also used as a solvent in the production of hydrogen peroxide, as a carrier for pigments in the manufacture of pigment pastes for plastics.
Disflamoll TOF has a very good resistance to low temperatures and weathering. Disflamoll® TOF is compatible with PVC, PUR, NBR, SBR and EPDM.
Disflamoll TOF has a shelf life of 2 years.
DISFLAMOLL TOF is a halogen free phosphate plasticizer with a very good resistance to low temperatures and weathering.
Disflamoll TOF is suitable for use with many types of polymers including flexible PVC, PUR, NBR, SBR.
Disflamoll TOF is a strong, moderately polar solvent.
Disflamoll TOF is particularly beneficial to use Disflamoll TOF when resistance to extremely low temperatures is required along with good light stability and weathering resistance.
Furthermore Disflamoll TOF is used as a solvent in the production of hydrogen peroxide, as a carrier for pigments in the manufacture of pigment pastes for plastics and as an additive for mineral oils.

Disflamoll TOF Chemical Properties
Melting point: -70°C
Boiling point: 215 °C4 mm Hg(lit.)
Density: 0.92 g/mL at 20 °C(lit.)
Vapor pressure: 2.1 mm Hg ( 20 °C)
Refractive index: n20/D 1.444(lit.)
Fp: >230 °F
Storage temp.: Store below +30°C.
Solubility: <0.001g/l
Form: Liquid
Specific Gravity: 0.93
Color: Colourless
PH: 7 (H2O, 20℃)
Water Solubility: BRN: 1715839
CAS DataBase Reference: 78-42-2(CAS DataBase Reference)
NIST Chemistry Reference: Disflamoll TOF (3:1)(78-42-2)
EPA Substance Registry System: Disflamoll TOF (78-42-2)

Disflamoll TOF, a clear, viscous liquid, is used as a component of vinyl stabilizers, grease additives, and flame-proofing compositions; however, it is used primarily as a plasticizer for vinyl plastic and synthetic rubber compounds.
Disflamoll TOF has been employed as a specialty flameretardant plasticizer for vinyl compositions where low temperature flexibility is critical, eg, in military tarpaulins.
Disflamoll TOF can be included in blends with general purpose plasticizers such as phthalate esters to improve low temperature flexibility.

Uses
Disflamoll TOF is used as a phosphorous flame retardant.
Used as a plasticizer in the preparation of a new potentiometric membrane sensor.
Solvent, antifoaming agent, plasticizer.
Disflamoll TOF is a phosphate plasticizer offering excellent low temperatures properties as well as good resistance to weathering.
Disflamoll TOF is suitable for use in many types of polymers including flexible PVC, PUR, NBR, SBR and EPDM.
Disflamoll TOF is a strong, moderately polar solvent.
Disflamoll TOF is also used as a solvent in the production of hydrogen peroxide, as a carrier for pigments in the manufacture of pigment pastes for plastics and as an additive for mineral oils.

Reactivity Profile
Disflamoll TOF is incompatible with oxidizing materials.
Disflamoll TOF may soften or deteriorate certain plastics and elastomers.
Disflamoll TOF is incompatible with cellulose acetate and cellulose acetate butyrate.

Purification Methods
Disflamoll TOF, in an equal volume of diethyl ether, is shaken with aqueous 5% HCl, and the organic phase is filtered to remove traces of pyridine (used as a solvent during manufacture) as its hydrochloride.
This layer is shaken with aqueous Na2CO3, then water, and the ether is distilled off at room temperature.
The ester is then filtered, dried for 12hours at 100o/15mm, and again filtered, then shaken intermittently for 2days with activated alumina (100g/L).
Disflamoll TOF is decanted through a fine sintered-glass disc (with exclusion of moisture), and distilled under vacuum.
DISODIUM 2-SULFOLAURATE
DISODIUM ASCORBYL SULFATE Nom INCI : DISODIUM ASCORBYL SULFATE Classification : Sulfate Ses fonctions (INCI) Antioxydant : Inhibe les réactions favorisées par l'oxygène, évitant ainsi l'oxydation et la rancidité
DISODIUM ASCORBYL SULFATE
DISODIUM AZELATE, N° CAS : 17265-13-3 / 27825-99-6 / 132499-85-5, Nom INCI : DISODIUM AZELATE. Nom chimique : Nonanedioic acid, disodium. N° EINECS/ELINCS : 241-298-4 / - / -, Ses fonctions (INCI). Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
DISODIUM AZELATE
DISODIUM C12-14 PARETH-3 SULFOSUCCINATE, N° CAS : 68815-56-5, Nom INCI : DISODIUM C12-14 PARETH-3 SULFOSUCCINATE, Nom chimique : Poly(oxy-1,2-ethanediyl), \a-(3-carboxy-1-oxosulfopropyl)-\w-hydroxy-, C10-16-alkyl ethers, disodium salts. Ses fonctions (INCI). Agent nettoyant : Aide à garder une surface propre. Sinergiste de mousse : Améliore la qualité de la mousse produite en augmentant une ou plusieurs des propriétés suivantes: volume, texture et / ou stabilité. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISODIUM C12-14 PARETH-3 SULFOSUCCINATE
Nom INCI : DISODIUM CAPRYLOYL GLUTAMATE Ses fonctions (INCI) Agent nettoyant : Aide à garder une surface propre Déodorant : Réduit ou masque les odeurs corporelles désagréables Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISODIUM CAPRYLOYL GLUTAMATE
butanedioic acid; sulfo-, C-C16-18-alkyl esters disodium salt cas no: 91697-07-3
DISODIUM CETEARYL SULFOSUCCINATE
DISODIUM CETEARYL SULFOSUCCINATE, N° CAS : 91697-07-3, Nom INCI : DISODIUM CETEARYL SULFOSUCCINATE, N° EINECS/ELINCS : 294-268-8, Ses fonctions (INCI): Agent nettoyant : Aide à garder une surface propre. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Agent moussant : Capture des petites bulles d'air ou d'autres gaz dans un petit volume de liquide en modifiant la tension superficielle du liquide Sinergiste de mousse : Améliore la qualité de la mousse produite en augmentant une ou plusieurs des propriétés suivantes: volume, texture et / ou stabilité Hydrotrope : Augmente la solubilité d'une substance qui est peu soluble dans l'eau. Agent d'entretien de la peau : Maintient la peau en bon état Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISODIUM CETYL SULFOSUCCINATE
DISODIUM COCAMIDO MEA-SULFOSUCCINATE, N° CAS : 68784-08-7 / 61791-66-0. Nom INCI : DISODIUM COCAMIDO MEA-SULFOSUCCINATE. N° EINECS/ELINCS : 272-219-1. Classification : MEA. Ses fonctions (INCI): Agent nettoyant : Aide à garder une surface propre. Agent moussant : Capture des petites bulles d'air ou d'autres gaz dans un petit volume de liquide en modifiant la tension superficielle du liquide. Hydrotrope : Augmente la solubilité d'une substance qui est peu soluble dans l'eau.Agent d'entretien de la peau : Maintient la peau en bon état Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISODIUM COCAMIDO MEA-SULFOSUCCINATE
Disodium Cocoamphodiacetate; Uniteric C2M; Chemteric C2M; Onium compounds,1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkylimidazolium, inner salts, disodium salts; cas no: 68650-39-5
DISODIUM COCOAMPHODIACETATE
Disodium Cocoamphodiacetate is a clear yellow liquid with mild characteristic odor.
Disodium Cocoamphodiacetate is derived from coconut.
Disodium Cocoamphodiacetate is made from fatty acids from coconut oil, also called coconut acid.


CAS Number: 68650-39-5
EC Number: 272-043-5
Chem/IUPAC Name: Disodium N-2-(N-(2-carboxymethoxyethyl)-N-carboxymethylamino)ethylcocamide


Disodium Cocoamphodiacetate is a concentrated, mild amphoteric surfactant for hair and skin cleansing products.
Disodium Cocoamphodiacetate is also preservative-free.
Disodium Cocoamphodiacetate is one of the mildest amphoteric surfactants of its class.


Disodium Cocoamphodiacetate is a thick Viscous liquid.
Disodium Cocoamphodiacetate is an amphoteric surfactant and contains 20-40% active substance.
Disodium Cocoamphodiacetate comes from the fatty acids found in coconut oil .


Disodium Cocoamphodiacetate remains stable when stored in a closed, light-protected container in a cool, dry place.
Like many surfactants, Disodium Cocoamphodiacetate is originally derived from coconut.
Disodium Cocoamphodiacetate is a amphoteric secondary surfactant with high dermatological tolerance, with good foaming and wetting properties even in the presence of salts, oils or in hard water.


This is a preservative-free concentrated solution of natural origins (concentrated solution 45% minimum).
Disodium Cocoamphodiacetate is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).


Disodium Cocoamphodiacetate also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
Disodium Cocoamphodiacetate is produced by the reaction of cocamidopropyl betaine with diethylenetriamine pentaacetic acid.
Disodium Cocoamphodiacetate is made from fatty acids from coconut oil, also called coconut acid.


Disodium Cocoamphodiacetate cleans the skin and hair by helping water to mix with oil and dirt so that these substances can be rinsed away.
They also increase foaming capacity or stabilize foams.
Disodium Cocoamphodiacetate is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).


Disodium Cocoamphodiacetate increases the foaming power of a solution by increasing the surface viscosity of the liquid that surrounds the individual bubbles in a foam.
Disodium Cocoamphodiacetate is great for baby products and other non-irritating cleansers.


Disodium Cocoamphodiacetate is a surfactant produced on the basis of fatty acids derived from coconut oil.
Disodium Cocoamphodiacetate is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).


Disodium Cocoamphodiacetate also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
Disodium Cocoamphodiacetate is a mild amphoteric surfactant of light color, low viscosity, low irritation, high foamability and high thickening ability.


Sodium Cocoamphoacetate, Sodium Cocoamphopropionate, Disodium Cocoamphodiacetate and Disodium Cocoamphodipropionate are amber liquids with a faint fruity odor.
Disodium Cocoamphodiacetate is an amphoteric surfactant commonly used in personal care products.


Disodium Cocoamphodiacetate is derived from the fatty acids found in coconut oil.
Disodium Cocoamphodiacetate is an imidazoline-derived amphoteric organic compound.
Disodium Cocoamphodiacetate is derived from coconut.


Disodium Cocoamphodiacetate is a mild amphoteric surfactant of light color, low viscosity, low irritation, high foamability and high thickening ability.
Disodium Cocoamphodiacetate is a synthetic amphoteric surfactant routinely used in personal care products.



USES and APPLICATIONS of DISODIUM COCOAMPHODIACETATE:
Disodium Cocoamphodiacetate is a Mild Surfactant for Baby Bath Products & Shampoos.
Disodium Cocoamphodiacetate is an Extremely mild, amphoteric surfactant which is not defatting to the skin and also does not strip oils from hair.
Disodium Cocoamphodiacetate is a moderate foamer and is recommended for sensitive skin, baby skin, facial products.


Disodium Cocoamphodiacetate is used for use in shampoos and body wash where optimum foam is desired, combine with another surfactant such as decyl glucoside and/or cocamidopropyl betaine for a mild high-foaming blend.
Disodium Cocoamphodiacetate is used for Baby Shampoos a surfactant which is having a quality mild, amphoteric, foaming and cleansing agent that can reduce the overall irritation of products is required.


Disodium Cocoamphodiacetate is often used in sensitive skin formulations like baby shampoos, shampoos, bath and shower body washes, and facial products.
Disodium Cocoamphodiacetate is compatible with anionic, non-ionic and most cationic systems.
In personal care /skin and hair care this coconut oil-derived surfactant, Disodium Cocoamphodiacetate, may be used with another surfactant, such as

cocomidopropyl betaine or decyl glucoside to make a gentle foam, high-performance product.
Disodium Cocoamphodiacetate is used in many household and industrial applications too.
Disodium Cocoamphodiacetate is stable over a broad pH range.


Easy to use Disodium Cocoamphodiacetate is great in many applications, including personal care and industrial applications.
Disodium Cocoamphodiacetate improves conditioning on skin and hair at acidic pH.
In personal care formulations like bubble baths, shampoos, & body cleansers, Disodium Cocoamphodiacetate makes a moderate lather, cleans without defatting the skin, giving a rich, conditioning effect.


Disodium Cocoamphodiacetate is stable over a wide pH range which makes it ideal for many personal care, household, and industrial applications.
In addition to personal care products, Disodium Cocoamphodiacetate is useful for the formulation of products used around food preparation areas, and high alkaline hard surface cleaners.


Disodium Cocoamphodiacetate is a mild detergent cleansing agent derived from coconut; most often used in facial cleansers.
Disodium Cocoamphodiacetate is in appearance, a Gold viscous liquid with its pH 8.5 - 9.5 and a Customary Usage: 1% - 50% depending on the final application.


Ideal for use in all types of industrial cleaners etc. since it aids in flash foaming and improves the foam stability in formulations.
Disodium Cocoamphodiacetate is non-toxic and biodegradable.
Disodium Cocoamphodiacetate is used creamy detergents for sensitive skin and frizzy hair.


Disodium Cocoamphodiacetate is gentle even on mucous tissues and therefore ideal for homemade feminine hygiene detergents.
Disodium Cocoamphodiacetate is also recommended for use in baby skin care products.
Disodium Cocoamphodiacetate is also used in Premium quality of Shampoos & Face Wash.


Most of the Anionic surfactants such as Sodium laureth Sulfate, Ammonium Laureth Sulfate, Disodium Laureth Sulfosuccinates contains sulfate contents which is harsh in nature.
These surfactants cause damage to hair strands & reduce the moisturisation properties of the shampoo.


Disodium Cocoamphodiacetate being amphoteric and having no sulfate content if when used in combination with these anionic surfactants provides excellent results further it also enhances the moisturisation & conditioning properties of the finished shampoo.
Hence, a range of Mild wash & bath products can be formulated with Disodium Cocoamphodiacetate such as Baby Bath, Shower Gel, Face Wash, Liquid Hand

Wash, 2 in 1 Shampoo Conditioners etc.
Disodium Cocoamphodiacetate is also stable & compatible to various other ingredients which are conventionally used in Shampoos.
Disodium Cocoamphodiacetate is produced by some renowned organizations which are into complete varieties of surfactants for the cosmetic Industries.


Disodium Cocoamphodiacetate is used as a surfactant in many skin and hair care products such as shampoos, body washes, and facial cleansers.
Disodium Cocoamphodiacetate has emulsifying properties that make it effective in removing dirt, oil, and other residues from the surface of the skin and hair.


Disodium Cocoamphodiacetate, also known as DCCA, is a surfactant commonly used in skin and hair care products.
Disodium Cocoamphodiacetate is known for its ability to produce a soft and creamy foam, making it pleasant to use in hair and skin care products.
Additionally, Disodium Cocoamphodiacetate is considered safe and effective in cleaning hair and skin without causing irritation or unwanted side effects.


One of the main features of Disodium Cocoamphodiacetate is its ability to maintain moisture in the skin and hair.
Disodium Cocoamphodiacetate is able to retain the natural moisture of the skin and hair, thus preventing them from becoming dry and brittle.
Disodium Cocoamphodiacetate is also used as an ingredient in baby care products due to its gentleness and ability to keep the skin soft and moisturized.


Furthermore, Disodium Cocoamphodiacetate is commonly used in products for the care of hospitalized patients, as it is considered safe and effective even for the most sensitive skin.
Disodium Cocoamphodiacetate is a surfactant widely used in skin and hair care products due to its emulsifying and moisturizing properties.


Disodium Cocoamphodiacetate enhances the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment.
Disodium Cocoamphodiacetate is derived from the fatty acids of coconuts and is used as a natural cleanser and conditioner.


Disodium Cocoamphodiacetate’s used often in hair products because it is such an effective yet mild cleanser that does not strip the hair of its natural oils.
Disodium Cocoamphodiacetate is a surfactant that can be used as an antimicrobial agent.


Disodium Cocoamphodiacetate is also a component of the analytical method for measuring fatty acids in plant material.
Disodium Cocoamphodiacetate has been shown to have antimicrobial activity against Gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa.


Disodium Cocoamphodiacetate does not interact with the hydroxyl group of the fatty acid, but reacts with the acidic hydrogen on the carboxyl group, which leads to oxidation and degradation of the molecule.
Disodium Cocoamphodiacetate can be used for wastewater treatment and as an oxidation catalyst in organic synthesis.


Disodium Cocoamphodiacetate is a soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Disodium Cocoamphodiacetate also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.


Disodium Cocoamphodiacetate is used Baby baths, mild shampoo, skin cleanser, bubble baths, detergent.
Disodium Cocoamphodiacetate works as a mild foaming agent, cleanser, and skin/hair conditioner.
As a foam booster, Disodium Cocoamphodiacetate increases a solution's foaming capacity by increasing the surface viscosity of the liquid which surrounds the individual bubbles in a foam.


Disodium Cocoamphodiacetate cleans the skin/hair by enabling water to mix with oil & dirt particles, and rinse them off the surface.
Disodium Cocoamphodiacetate's highly valued for cleansing the skin/hair without stripping it of its natural oils, and is thus incorporated into many "moisturizing" cosmetic cleaning products.


Disodium Cocoamphodiacetate is a mild foaming agent.
Disodium Cocoamphodiacetate increases the foaming power of a solution by increasing the surface viscosity of the liquid that surrounds the individual bubbles in a foam.


In cosmetics and personal care products, these four ingredients are used in the formulation of shampoos, and other hair products, and skin cleansing products.
Disodium Cocoamphodiacetate used in Antidandruff Shampoo - Very Mild, Baby Body Wash, Conditioning Shampoo - Silicone Free, Facial Cleanser - Soap
Like Feeling, Scalp Treatment Shampoo C-180, Shampoo - Colour Protection C-151, Shower Gel - Ultra Mild C-248, Strengthening Shampoo.


Disodium Cocoamphodiacetate’s widely used in mild shampoo, body wash, facial cleanser, hand soap, shaving products and so on, as primary or secondary surfactant.
Disodium Cocoamphodiacetate is authorized in organic products.


Disodium Cocoamphodiacetate is widely used in the preparation of low-irritant shampoo, various facial cleansers, shower gels, pet detergents, facial cleansers and shaving creams, etc.
Recommended dosage of Disodium Cocoamphodiacetate: 1.0-10.0%
Disodium Cocoamphodiacetate is widely used in mild shampoo, body wash, facial cleanser, hand soap, shaving products, as primary or secondary surfactant.


-Main Uses of Disodium Cocoamphodiacetate:
*Shampoos & Hand Soap (5% -25%)
*Body Wash (5%-30%)
*Bubble Bath (10%-30%)
*Premoistened Wipes (1%-4%)
*Hard Surface Cleaners (1%-3%)
*Compatible with anionic, non-ionic and most cationic systems.


-Cosmetic Uses:
*cleansing agents
*hair conditioning
*skin conditioning
*surfactants
*surfactant - foam boosting
*surfactant - hydrotrope



FUNCTIONS of DISODIUM COCOAMPHODIACETATE:
*Cleansing :
Disodium Cocoamphodiacetate helps to keep a clean surface
*Foam boosting :
Disodium Cocoamphodiacetate improves the quality of the foam produced by increasing one or more of the following properties: volume, texture and/or stability
*Hair conditioning :
Disodium Cocoamphodiacetate leaves hair easy to comb, soft, soft and shiny and / or confers volume, lightness and shine
*Hydrotrope :
Disodium Cocoamphodiacetate increases the solubility of a substance with low solubility in water.
*Skin conditioning :
Disodium Cocoamphodiacetate maintains skin in good condition
*Surfactant :
Disodium Cocoamphodiacetate reduces the surface tension of cosmetics and contributes to the even distribution of the product when it is used
Disodium Cocoamphodiacetate is used in personal care products such as baby shampoos, baby baths, skin cleansers for sensitive skin, shower shampoos, intimate hygiene and liquid soaps.



BENEFITS of DISODIUM COCOAMPHODIACETATE:
*Gentle for eyes and skin
*Compatible with all surfactants especially cheaper lauryl (ether) sulphates
*Preservative free and non-toxic
*Excellent foaming even using salt water, in oil or soap
*Good resistance to hard water



WHAT IS DISODIUM COCOAMPHODIACETATEUSED FOR:
Disodium Cocoamphodiacetate works as a mild foaming agent, cleanser and skin/hair conditioner.
As a foam booster, Disodium Cocoamphodiacetate increases a solution's foaming capacity by increasing the surface viscosity of the liquid which surrounds the individual bubbles in a foam.

Disodium Cocoamphodiacetatecleans the skin/hair by enabling water to mix with oil & dirt particles and rinse them off the surface.
Disodium Cocoamphodiacetate cleanses the skin/hair without stripping it of its natural oils and is thus incorporated into many "moisturizing" cosmetic cleaning products.

Skin care: Disodium Cocoamphodiacetate is used in a wide variety of skin care products such as facial cleanser, body wash, acne treatment, exfoliant/scrub, mascara and eye makeup remover

Hair care: Disodium Cocoamphodiacetate is used as a hair conditioning agent, as it helps improve the look and feel of dry & damaged hair by restoring it with body, suppleness and sheen.
Disodium Cocoamphodiacetate is used in shampoo, baby shampoo, hair mask and conditioner



DISODIUM COCOAMPHODIACETATE CHARACTERISTICS:
Good compatibility with various surfactants and compatibility with soap bases; Disodium Cocoamphodiacetate is mild to the skin and eyes, and the combination with anions can significantly reduce its irritation; Good foamability, stable in the range of pH (2-13), not affected by changes in water hardness or pH value; easily biodegradable, with a degradation rate of more than 97%, good safety.



PROPERTIES of DISODIUM COCOAMPHODIACETATE:
Disodium Cocoamphodiacetate acts as a mild foaming agent. Cleanses the skin without removing the natural oils of the skin.
Disodium Cocoamphodiacetate is effective in hair products, it acts as an emollient.
Disodium Cocoamphodiacetate helps to improve the look and feel of dry and damaged hair.
Disodium Cocoamphodiacetate increases the foaming ability of the products.
Disodium Cocoamphodiacetate is a mild non-irritant ingredient, suitable for sensitive skin.



FUNCTIONS of DISODIUM COCOAMPHODIACETATE IN COSMETIC PRODUCTS:
*CLEANSING:
Cleans skin, hair or teeth

*HAIR CONDITIONING:
Leaves the hair easy to comb, supple, soft and shiny and / or imparts volume

*SKIN CONDITIONING:
Maintains the skin in good condition

*SURFACTANT - CLEANSING:
Surface-active agent to clean skin, hair and / or teeth

*SURFACTANT - FOAM BOOSTING:
Improves foam quality by increasing volume, structure and / or durability

*SURFACTANT - HYDROTROPE:
Enhances the solubility of substances in water



SAFETY PROFILE of DISODIUM COCOAMPHODIACETATE:
Disodium cocoamphodiacetate is a non-irritating ingredient ideal for delicate skin types.



INDICATIONS of DISODIUM COCOAMPHODIACETATE:
Disodium Cocoamphodiacetate can be used as an additional surfactant to reduce the aggressive qualities of primary anionic surfactants (for example Sodium Laureth Sulphate).
Disodium Cocoamphodiacetate has conditioning properties that make it ideal even for the most rebel hair.
Disodium Cocoamphodiacetate is very gentle and can be used as a base for every-day usage products.
Disodium Cocoamphodiacetate is compatible with all types of surfactants (anionic, non-ionic and amphoteric).



DISODIUM COCOAMPHODIACETATE ALTERNATIVES:
*COCAMIDOPROPYL BETAINE, SODIUM LAURAMINOPROPIONATE



BENEFITS FOR YOUR HAIR:
*GENTLE CLEANSING:
Disodium Cocoamphodiacetate cleans the hair by enabling water to mix with oil and dirt particles, and rinse them off the surface.
Disodium Cocoamphodiacetate's highly valued for cleansing the hair without stripping it of its natural oils.

*PROMOTES HYDRATION AND SOFTNESS:
As a conditioning agent, Disodium Cocoamphodiacetate moisturizes the hair, leaving it smoother and softer than before.

*PROMOTES DETANGLING:
As it is conditioning and hydrating, Disodium Cocoamphodiacetate helps to make the hair easier to detangle as the hair gets softer.

*TLDR:
Disodium Cocoamphodiacetate is a mild, cleansing agent which increases the foaming ability of formulas while promoting hydration, softness, and makes the hair easier to detangle.
Disodium Cocoamphodiacetate provides a gentle cleanse and is great in products for children.



WHAT DOES DISODIUM COCOAMPHODIACETATE DO IN A FORMULATION?
*Cleansing
*Foam boosting
*Foaming
*Hair conditioning
*Surfactant



FUNCTIONS of DISODIUM COCOAMPHODIACETATE:
1. Cleanser (Cosmetics) - Improves the cleansing properties of water
2. Foaming Agent / Foam Booster - A type of surfactant that aids the formation of foam
3. Surfactant - Reduces the surface tension to allow mixtures to be formed evenly.
Emulsifier is a specific type of surfactant which allows two liquids to mix together evenly

Disodium Cocoamphodiacetate works as a mild foaming agent, cleanser and skin/hair conditioner.
As a foam booster, Disodium Cocoamphodiacetate increases a solution's foaming capacity by increasing the surface viscosity of the liquid which surrounds the individual bubbles in a foam.

Disodium Cocoamphodiacetate cleans the skin/hair by enabling water to mix with oil & dirt particles, and rinse them off the surface.
Disodium Cocoamphodiacetate's highly valued for cleansing the skin/hair without stripping it of its natural oils, and is thus incorporated into many "moisturizing" cosmetic cleaning products.

Furthermore, Disodium Cocoamphodiacetate's particularly effective as a hair conditioning agent, because it helps improve the look and feel of dry/damaged hair by restoring it with body, suppleness and sheen.
A mild and non-irritating ingredient, Disodium Cocoamphodiacetate's apprpriate for even the most sensitive skin types and gentle enough for baby products.

You can find Disodium Cocoamphodiacetate in a wide variety of personal care products such as shampoo/conditioner, facial cleanser, body wash, acne treatment, exfoliant/scrub, mascara and eye makeup remover.



BIODEGRADABILITY of DISODIUM COCOAMPHODIACETATE:
A 2008 study suggested high levels of Disodium Cocoamphodiacetate (>216 mg/L) may be toxic to bacteria in wastewater treatment processes.
Results from the 2008 research indicated that Disodium Cocoamphodiacetate has limited biodegradability and recalcitrant metabolites may develop.



WHY IS DISODIUM COCOAMPHODIACETATEUSED IN COSMETICS AND PERSONAL CARE PRODUCTS:
Sodium Cocoamphoacetate, Sodium Cocoamphopropionate, Disodium Cocoamphodiacetate, and Disodium Cocoamphodipropionate clean the skin and hair by helping water to mix with oil and dirt so that these substances can be rinsed away.
They also increase foaming capacity or stabilize foams.

These ingredients enhance the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment.
Sodium Cocoamphoacetate, Sodium Cocoamphopropionate, Disodium Cocoamphodiacetate and Disodium Cocoamphodipropionate are made from fatty acids from coconut oil, also called coconut acid.



PHYSICAL and CHEMICAL PROPERTIES of DISODIUM COCOAMPHODIACETATE:
Boiling Point: 100°C
Melting Point: -12°C
pH: 8.0
Solubility: Soluble in water
Form: Liquid
Physical state: Liquid
Color: Yellow
Odor: Characteristic
Odor Threshold: No data available
pH (As Is): 8
Melting point/range: No data available
Boiling point/boiling range: >100°C
Flash Point: No data available
Flammability: No data available
Auto-ignition temperature: No data available
Water solubility: Soluble
Solubility in other solvents No data available
Partition coefficient (n-Octanol/water): No data available
Vapor Density: > 1
Evaporation rate: > 1
Vapor Pressure (25°C): ~20 mm
Specific Gravity (25°C): 1.17
Oxidation/Reduction Potential: No data available
Viscosity: No data available
Explosive properties: No data available
Thermal decomposition: No data available
Lower explosion limit: No data available
Upper explosion limit: No data available



FIRST AID MEASURES of DISODIUM COCOAMPHODIACETATE:
-Description of necessary first-aid measures:
*General advice:
First aider needs to protect himself/herself.
Place affected clothing in a sealed bag for subsequent decontamination.
*Inhalation:
Remove victim to fresh air.
*Skin contact:
In case of contact with substance, immediately flush skin with running water for at least 20 minutes.
Remove and isolate contaminated clothing and shoes.
If skin irritation continues:
Get medical attention.
*Eye contact:
In case of contact with substance, immediately flush eyes with running water for at least 20 minutes.
consult a physician.
*Ingestion:
Drink water as a precaution.



ACCIDENTAL RELEASE MEASURES of DISODIUM COCOAMPHODIACETATE:
-Personal precautions, protective equipment and emergency procedures:
Wear suitable protective equipment.
Do not touch damaged containers or spilled material unless wearing suitable protective clothing.
-Methods for Cleaning or Taking Up:
*Small Spills:
Take up with sand or other non-combustible absorbent material and place into containers for later disposal.
*Large Spills:
Dike far ahead of spill for later disposal.
To avoid gelling and foaming problems, do not use water to flush to industrial sewer.
-Additional advice:
Prevent entry into waterways, sewers, basements or confined areas.



FIRE FIGHTING MEASURES of DISODIUM COCOAMPHODIACETATE:
-Extinguishing media:
*Suitable extinguishing media:
Water Spray, CO2, Dry Chemical, BC/ABC Extinguishers
-Advice for firefighters:
*Special protective equipment:
Full protective suit



EXPOSURE CONTROLS/PERSONAL PROTECTION of DISODIUM COCOAMPHODIACETATE:
-Components with workplace control parameters:
--Control Measures:
*Engineering measures:
Apply technical measures to comply with any occupational exposure limits when applicable.
-Personal protective equipment:
*Respiratory protection:
In the case of insufficient ventilation, wear suitable respiratory equipment.
*Hand protection:
Wear appropriate gloves.
*Eye protection:
Wear safety goggles.
*In case of contact through splashing:
Wear face-shield and protective suit.
*Skin and Body protection:
Wear appropriate clothing to avoid direct skin contact.
Remove and wash contaminated clothing before wearing again.
*Hygiene measures:
Wash hands before breaks and immediately after handling the product.
Shower or bathe at the end of working.
When using the product do not eat, drink or smoke.



HANDLING and STORAGE of DISODIUM COCOAMPHODIACETATE:
-Storage:
Recommended: Store between 10 - 49 °C.
Keep container tightly closed when not in use.



STABILITY and REACTIVITY of DISODIUM COCOAMPHODIACETATE:
-Chemical Stability:
Stable under normal conditions



SYNONYMS:
Imidazolium compounds
1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, sodium salts
DISODIUM COCOAMPHODIACETATE
Imidazolium compounds, 1-2-(carboxymethoxy)ethyl-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, inner salts, disodium salts
Imidazolium compounds, 1-(2-(carboxymethoxy)ethyl)-1-(carboxymethyl)-4 ,5-dihydro-2-norco- co alkyl, hydroxides, disodium salts
COCOAMPHOCARBOXYGLYCINATE
Coconut fatty acid, aminoethylethanolamine imidazoline, dicarboxymethylated, disodium salt
Imidazolium compounds, 1-[2-(carboxymethoxy) Coconut alkyl-1-(2-hydroxyethyl)-2-imidazoline, reaction product with sodium chloroacetate
Amphoterge(R) W-2
DSCADA
Disodium N-2-(N-(2-carboxymethoxyethyl)-N-carboxymethylamino)ethylcocamide
Cocoamphocarboxyglycinate oxide
Disodium cocoamphodiacetate
Cocoamphocarboxyglycinate
Coconut fatty acid, aminoethylethanolamine imidazoline, dicarboxymethylated, disodium salt
Cocoamphocarboxyglycinate, disodium salt
Imidazolium compounds, 1-(2-(carboxymethoxy)ethyl)-1-(carboxymethyl)-4,5-dihydro-2-norcoco alkyl, hydroxides, inner salts, disodium salts



DISODIUM COCOAMPHODIACETATE
Disodium Cocoamphodiacetate is a mild amphoteric surfactant of light color, low viscosity, low irritation, high foamability and high thickening ability.
Disodium cocoamphodiacetate increases the foaming power of a solution by increasing the surface viscosity of the liquid surrounding the individual bubbles in a foam.
Disodium cocoamphodiacetate works as a mild foaming agent, cleanser and skin/hair conditioner.

CAS Number: 68650-39-5
EINECS Number: 272-043-5

Disodium cocoamphodiacetate is a synthetic amphoteric surfactant routinely used in personal care products.
Disodium cocoamphodiacetate’s widely used in mild shampoo, body wash, facial cleanser, hand soap, shaving products and so on, as primary or secondary surfactant.
As a foam booster, it increases a solution's foaming capacity by increasing the surface visosity of the liquid which surrounds the individual bubbles in a foam.

Disodium cocoamphodiacetate is an amphoteric surfactant commonly used in personal care products.
Disodium Cocoamphodiacetate is a chemical compound commonly used in cosmetics and personal care products, such as shampoos, body washes, and facial cleansers.
Disodium cocoamphodiacetate is a surfactant and a mild cleansing agent that helps to remove dirt, oil, and impurities from the skin and hair.

Disodium cocoamphodiacetate is amber liquids with a faint fruity odor.
In cosmetics and personal care products, Disodium cocoamphodiacetate is used in the formulation of shampoos and other hair products, and skin cleansing products.
Disodium cocoamphodiacetate cleans the skin and hair by helping water to mix with oil and dirt so that these substances can be rinsed away.

Disodium cocoamphodiacetate also increases foaming capacity or stabilize foams.
Disodium cocoamphodiacetate enhances the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment.
Disodium cocoamphodiacetate is an amphoteric surfactant commonly used in personal care products.

Disodium cocoamphodiacetate is a mild foaming agent.
Derived from the fatty acids found in coconut oil.
An imidazoline-derived amphoteric organic compound.

Disodium cocoamphodiacetate cleans the skin/hair by enabling water to mix with oil & dirt particles, and rinse them off the surface.
Disodium cocoamphodiacetate is used in many household and industrial applications too.

Disodium cocoamphodiacetate is stable over a broad pH range. Ideal for use in all types of industrial cleaners etc.
Since Disodium cocoamphodiacetate aids in flash foaming and improves the foam stability in formulations.

Disodium cocoamphodiacetate is non-toxic and biodegradable.
Disodium Cocoamphodiacetate is with an excellent toxicological profile.
In general, Baby shampoo is formulated so that it is less irritating to the eyes.

Most contain sodium trideceth sulfate, alternatively, baby shampoo may be formulated using other classes of surfactants, most notably non-ionics which are much milder than any
charged anionics used.
Ideally, in Baby Shampoos the conventionally used anionic surfactant i.e.
Disodium cocoamphodiacetate is used at 10 to 15% levels and the major surfactant component is formed by Disodium Cocoamphodiacetate by using it at 20 to 25% levels.

Other ingredients in a Baby Shampoo may include Cocoamidopropyl betaine.
Disodium cocoamphodiacetate, PEG 150 Distearates, Preservatives, Humectants & Conditioning Agents.
Most of the Leading Baby Shampoos are formulated without addition of Colors.

As observed, Disodium cocoamphodiacetate light amber in appearance which is the natural color of the formulation.
In case, where absolute color free shampoo is desired, another equivalent surfactant Disodium lauroamphoacetate is used.
Disodium cocoamphodiacetate comes in very light yellowish clear liquid.

This refers to the presence of two sodium ions in the molecule.
This part of the compound is derived from coconut oil.
Disodium cocoamphodiacetate's an amphoteric surfactant, which means it can function as both an anionic (negatively charged) and cationic (positively charged) surfactant, depending on the pH of the product.

This indicates that the compound contains two acetic acid (vinegar) groups.
Disodium Cocoamphodiacetate is known for its gentle cleansing properties and its ability to produce a rich lather in cosmetic products.
Disodium cocoamphodiacetate is often used in formulations designed for sensitive skin because it is considered mild and less likely to cause irritation compared to some other surfactants.

Additionally, Disodium cocoamphodiacetate can help stabilize formulations and improve their overall performance.
Disodium cocoamphodiacetate's highly valued for cleansing the skin/hair without stripping it of its natural oils, and is thus incorporated into many "moisturizing" cosmetic cleaning products.
Disodium cocoamphodiacetate (DSCADA) is a synthetic amphoteric surfactant routinely used in personal care products.

Disodium cocoamphodipropionate is a cleaning agent, or "surfactant," that can also be found in skin soaps, lotions and shampoos.
Disodium cocoamphodiacetate is made from fatty acids from coconut oil, also called coconut acid.
Disodium cocoamphodiacetate is used it in our products to remove dirt by helping water to mix with dirt and oils so they can be rinsed away.

Disodium cocoamphodipropionate can also be used as a wetting agent that helps a formula spread across a surface, making cleaning more efficient.
Disodium Cocoamphodiacetate primarily serves as a mild surfactant and cleansing agent in personal care products.
Its ability to create foam and remove dirt and oil from the skin and hair makes it a popular choice in shampoos, body washes, facial cleansers, and other cleansing products.

One of the key advantages of using Disodium Cocoamphodiacetate is its mildness.
Disodium cocoamphodiacetate is generally well-tolerated by most skin types, including sensitive skin, and is less likely to cause irritation or dryness compared to harsher surfactants.
Disodium Cocoamphodiacetate is considered to be biodegradable, which means it can break down naturally in the environment over time.

This is an important consideration for companies aiming to create more environmentally-friendly personal care products.
The amphoteric nature of Disodium Cocoamphodiacetate means it can function effectively across a range of pH levels.
Disodium cocoamphodiacetate is stable in both acidic and alkaline conditions, making it versatile in various cosmetic formulations.

While Disodium Cocoamphodiacetate is a popular choice, there are many other surfactants available for formulators to consider when creating personal care products.
The choice of surfactant depends on the specific requirements of the product, including its intended use and target consumer.
Disodium cocoamphodiacetate is amber liquids with a faint fruity odor.

A soft, mild cleansing agent with amphoteric structure meaning that its head contains both a positively and a negatively charged part (surfactants are most commonly anionic meaning their head has a negative charge).
Disodium cocoamphodiacetate also has great foaming abilities and is recommended for baby products and other non-irritating cleansers.
Disodium Cocoamphodiacetate cleans the skin and hair by helping water to mix with oil and dirt so that these substances can be rinsed away.

Disodium cocoamphodiacetate also increases foaming capacity or stabilize foams.
Disodium cocoamphodiacetate enhances the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment.
Disodium Cocoamphodiacetate is an Extremely mild, amphoteric surfactant which is not defatting to the skin and also does not strip oils from hair.

Disodium Cocoamphodiacetate is also used in Premium quality of Shampoos & Face Wash.
Most of the Anionic surfactants such as Sodium laureth Sulfate, Ammonium Laureth Sulfate, Disodium Laureth Sulfosuccinates contains sulfate contents which is harsh in nature.
Disodium cocoamphodiacetate causes damage to hair strands & reduce the moisturisation properties of the shampoo.

Disodium Cocoamphodiacetate being amphoteric and having no sulfate content if when used in combination with these anionic surfactants provides excellent results further it also enhances the moisturisation & conditioning properties of the finished shampoo.
Hence, a range of Mild wash & bath products can be formulated with Disodium cocoamphodiacetate such as Baby Bath, Shower Gel, Face Wash, Liquid Hand Wash, 2 in 1 Shampoo Conditioners etc.

Disodium cocoamphodiacetate is also stable & compatible to various other ingredients which are conventionally used in Shampoos.
Disodium cocoamphodiacetate is produced by some renowned organizations which are into complete varieties of surfactants for the cosmetic Industries.
Disodium cocoamphoacetate is a natural based surfactant, used in personal care and industrial products.

Disodium cocoamphodiacetate is a mild and foaming agent in many shampoos, bubble baths and baby cleansers; Disodium cocoamphodiacetate is used in many washing-up liquids and hard surface detergents.
Disodium cocoamphodiacetate is derived from the fatty acids found in coconut oil.
Disodium cocoamphodiacetate is an imidazoline-derived amphoteric organic compound.

Disodium cocoamphodiacetate works as a mild foaming agent, cleanser and skin/hair conditioner.
As a foam booster, Disodium cocoamphodiacetate increases a solution's foaming capacity by increasing the surface viscosity of the liquid which surrounds the individual bubbles in a foam.
Disodium cocoamphodiacetate cleans the skin/hair by enabling water to mix with oil & dirt particles, and rinse them off the surface.

Disodium cocoamphodiacetate's highly valued for cleansing the skin/hair without stripping it of its natural oils, and is thus incorporated into many "moisturizing" cosmetic cleaning products.
Furthermore, it's particularly effective as a hair conditioning agent, because Disodium cocoamphodiacetate helps improve the look and feel of dry/damaged hair by restoring it with body, suppleness and sheen.

A mild and non-irritating ingredient, its apprpriate for even the most sensitive skin types and gentle enough for baby products.
Disodium cocoamphodiacetate can be found this ingredient in a wide variety of personal care products such as shampoo/conditioner, facial cleanser, body wash, acne treatment, exfoliant/scrub, mascara and eye makeup remover.
Disodium Cocoamphodiacetate is a amphoteric secondary surfactant with high dermatological tolerance, with good foaming and wetting properties even in the presence of salts, oils or in hard water.

This is a preservative-free concentrated solution of natural origins (concentrated solution 45% minimum).
Disodium cocoamphodiacetate can be used as an additional surfactant to reduce the aggressive qualities of primary anionic surfactants (for example Sodium Laureth Sulphate).
Disodium cocoamphodiacetate has conditioning properties that make it ideal even for the most rebel hair.

Disodium cocoamphodiacetate is very gentle and can be used as a base for every-day usage products.
Disodium cocoamphodiacetate is compatible with all types of surfactants (anionic, non-ionic and amphoteric).
Creamy detergents for sensitive skin and frizzy hair.

Vapor Pressure (25°C): ~20 mm
Specific Gravity (25°C): 1.17
Form: Liquid
Physical state: Liquid
Color: Yellow
Odor: Characteristic
pH (As Is): 8
Boiling point/boiling range: >100°C
Water solubility: Soluble
Vapor Density: > 1
Evaporation rate: > 1

Disodium cocoamphodiacetate is gentle even on mucous tissues and therefore ideal for homemade feminine hygiene detergents.
Also recommended for use in baby skin care products.
Disodium Cocoamphodiacetate is a moderate foamer and is recommended for sensitive skin, baby skin, facial products.

For use in shampoos and body wash where optimum foam is desired, combine with another surfactant such as decyl glucoside and/or ocamidopropyl betaine for a mild high-foaming blend.
For Baby Shampoos a surfactant which is having a quality mild, amphoteric, foaming and cleansing agent that can reduce the overall irritation of products is required.
Disodium Cocoamphodiacetate is often used in sensitive skin formulations like baby shampoos, shampoos, bath and shower body washes, and facial products.

In some formulations, Disodium Cocoamphodiacetate is used in combination with other surfactants to enhance cleansing and foaming properties.
Its compatibility with different surfactants allows formulators to create products with specific performance characteristics.
Disodium Cocoamphodiacetate is generally recognized as safe for use in cosmetics and personal care products by regulatory agencies such as the U.S. Food and Drug Administration (FDA) and the European Commission.

Disodium cocoamphodiacetate is compatible with anionic, non-ionic and most cationic systems.
In personal care/skin and hair care this coconut oil derived surfactant may be used with another surfactant, such as cocomidopropyl betaine or decyl glucoside to make a gentle high foam , high performance product.
Disodium cocoamphodiacetate is in appearance, a Gold viscous liquid with its pH 8.5 - 9.5 and a Customary Usage: 1% - 50% depending on the final application.

Disodium cocoanfodiacetate is an eco-certified secondary / primary amphoteric surfactant with high skin tolerability, good wetting and foaming power even in the presence of salts and oils, even in hard waters, without preservatives totally of natural origin.
Disodium cocoamphodiacetate is indicated for shampoos and detergents with conditioning action for difficult hair.

In personal care /skin and hair care this coconut oil derived surfactant may be used with another surfactant, such as cocomidopropyl betaine or decyl glucoside to make a gentle high foam , high performance product.
Biodegradation of an amphoteric surfactant commonly used in personal care products, disodium cocoamphodiacetate (DSCADA), was evaluated.
Results from respirometry experiments indicated that high levels of DSCADA (>216 mg/L) may be toxic to bacteria in wastewater treatment processes.

Limited biodegradation, with 50% dissolved organic carbon (DOC) removal and 80% chemical oxygen demand removal was observed in batch assays, while complete removal of the parent compound, DSCADA, was noted.
Oxygen biosensors were used to evaluate biodegradability of the metabolites present in the batch samples.
Additional aerobic microbial activity was not detected in these samples, even with a residual DOC of approximately 45 mg/L.

Results from this research indicate that biodegradability of DSCADA is limited and recalcitrant metabolites may be formed.
Because DSCADA is a commonly used surfactant and is present in domestic and industrial wastewater, the associated risk posed by residual
compounds should be carefully evaluated.

In addition to its use in skincare products, Disodium Cocoamphodiacetate is commonly found in hair care products such as shampoos and conditioners.
Its cleansing properties help remove excess oil, dirt, and styling products from the hair, leaving it clean and manageable.
Disodium Cocoamphodiacetate also has emulsifying properties, which means it can help mix oil and water-based ingredients in cosmetic formulations.

This is particularly useful in products like cream-based cleansers, lotions, and makeup removers, where it helps maintain product stability and consistency.
Formulators often appreciate the compatibility of Disodium Cocoamphodiacetate with a wide range of other cosmetic ingredients, including fragrances, botanical extracts, and preservatives.
This allows for the creation of complex and effective formulations.

Due to its mild nature and ability to create a foaming lather, Disodium Cocoamphodiacetate is a common choice in sulfate-free or low-sulfate formulations.
Sulfates, such as sodium lauryl sulfate, can be harsh on the skin and hair, so many consumers seek sulfate-free alternatives.
As environmental concerns grow, many cosmetic manufacturers are looking for more sustainable and eco-friendly alternatives.

Disodium Cocoamphodiacetate is considered relatively environmentally friendly because it is biodegradable and does not pose significant risks to aquatic life when used in normal concentrations.
When purchasing cosmetic products containing Disodium Cocoamphodiacetate, it's important to read the product label and follow any specific instructions or recommendations.
Disodium Cocoamphodiacetate is used in cosmetics and personal care products worldwide, and it can be found in a variety of brands and product lines, ranging from mass-market to high-end products.

Disodium Cocoamphodiacetate is a vegan friendly, naturally derived ingredient from the fatty acids found in coconut oil.
Disodium cocoamphodiacetate is a gentle and mild skin cleansing amphoteric ingredient.
Disodium cocoamphodiacetate helps to refresh and clean the skin and hair without stripping natural oils and moisture.

Disodium cocoamphodiacetate's gentle cleansing action works by helping water to mix with oil and dirt so they can be easily rinsed away.
As well as increasing foaming and helping to stabilise the bubbles, Disodium cocoamphodiacetate benefits baby’s skin and hair by gently cleansing while leaving it beautifully soft and supple.
Disodium cocoamphodiacetate is a non-irritating ingredient ideal for delicate skin types.

The expert panel Cosmetic Ingredient Review (CIR), has assessed this ingredient and found to be safe, non-toxic and non-irritating.
The Expert Panel reviewed newly available studies since that assessment, along with updated information regarding types and concentrations of use.
The Panel confirmed the safety of Cocoamphoacetate, Cocoamphopropionate, Cocoamphodiacetate, and Cocoampho-dipropionate in the practices of use and concentrations.

Disodium cocoamphodiacetate is a light foaming agent.
Disodium cocoamphodiacetate increases the foaming power of a solution by increasing the surface viscosity of the liquid surrounding the individual bubbles in a foam.
Disodium cocoamphodiacetate produces a high quality foam without being hindered by oil, making it widely compatible with a range of preexisting formulations without having to change a thing.

Working well in a lower pH range of between 4 and 9, Disodium Cocoamphodiacetate has an incredibly high resistance to hard water, working effectively even in salt water.
Disodium cocoamphodiacetate is compatible with anionic, non-ionic and amphoteric surfactants, thus adding to it's high-compatibility and easyto-use factors.
As Disodium cocoamphodiacetate is compatible with both the skin and the mucous membrane, it can also be used in gentle hair and facial cleansers without causing dryness or irritation, making it excellent for leave in conditioners as well as facial cleansers and scrubs.

Disodium Cocoamphodiacetate is added during the final stage of a cosmetic formulation for best results Cleans the skin and hair by helping water to mix with oil and dirt so that these substances can be rinsed away.
They also increase foaming capacity or stabilize foams.
These ingredients enhance the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment.

Uses
Imidazolium compounds, Disodium cocoamphodiacetate, hydroxides, sodium salts is a coco substituted imidazoline amphoteric surfactant.
This high foaming surfactant can be easily used in a broad number of personal care applications where mildness, foaming, and compatibility are important.

Disodium cocoamphodiacetate is often used as a key ingredient in facial cleansers and makeup removers.
Its mild cleansing action helps remove makeup, dirt, and excess oil from the skin without causing irritation.
Disodium Cocoamphodiacetate is found in many body washes and shower gels.

Disodium cocoamphodiacetate helps create a rich lather and effectively cleanses the skin, leaving it feeling refreshed.
Disodium cocoamphodiacetate acts as a gentle cleansing agent that helps remove dirt, sebum, and styling products from the hair and scalp.
Disodium cocoamphodiacetate is commonly used in both regular and sulfate-free shampoos.

Disodium Cocoamphodiacetate can be found in bubble bath products to create a foaming and cleansing effect, enhancing the overall bathing experience.
Disodium cocoamphodiacetate is often used in baby shampoos, body washes, and bath products to ensure gentle cleansing for delicate baby skin.
Some cream and gel-based facial cleansers use Disodium Cocoamphodiacetate as an emulsifying agent to help blend oil and water-based ingredients, improving product consistency.

Disodium cocoamphodiacetate may be used in makeup products, such as makeup removers or cleansing wipes, to help dissolve and remove makeup without drying out the skin.
Given its gentle and non-irritating properties, Disodium Cocoamphodiacetate is often incorporated into products designed for individuals with sensitive or easily irritated skin.
Disodium cocoamphodiacetate can be found in personal hygiene products like intimate washes and wipes, providing gentle cleansing while maintaining the skin's natural pH balance.

Disodium cocoamphodiacetate is used in various skincare products, including sunscreens, where it helps to disperse and evenly distribute active ingredients on the skin.
Disodium Cocoamphodiacetate is also commonly used in men's grooming products such as facial cleansers, shampoos, and shower gels.
Disodium cocoamphodiacetate can also be used as a base in extremely delicate detergents.

Disodium Cocoamphodiacetate is often featured in natural and organic cosmetics because of its plant-derived origin and mild properties.
Disodium cocoamphodiacetate aligns with the preferences of consumers seeking cleaner and greener beauty products.
Dermatologists may recommend cleansers containing Disodium Cocoamphodiacetate for patients with sensitive or problematic skin conditions, as it can effectively clean without aggravating skin issues.

Some personal lubricants use Disodium Cocoamphodiacetate as a gentle, non-irritating ingredient to enhance lubrication and reduce friction.
Disodium cocoamphodiacetate is used in foaming bath products such as bath foams and bath bombs to create luxurious foam and provide a mild cleansing effect during bathing.
Disodium Cocoamphodiacetate can be found in various spa and salon products, including body wraps, scrubs, and facial treatments, to cleanse and prepare the skin for subsequent treatments.

In natural soap formulations, Disodium Cocoamphodiacetate can be used to improve lathering and provide a gentle cleansing experience.
Some micellar water products, which are known for their gentle makeup removal properties, may contain Disodium Cocoamphodiacetate as one of their key ingredients.
As a versatile and mild ingredient, Disodium Cocoamphodiacetate can serve as a foundational component in various cosmetic formulations, helping to create stable and effective products.

In body scrub formulations, Disodium Cocoamphodiacetate can assist in distributing exfoliating particles evenly and providing a mild cleansing action.
In certain hand sanitizers, Disodium Cocoamphodiacetate may be used as an emulsifier or thickening agent to improve product texture and consistency.
Disodium cocoamphodiacetate is commonly featured in products specifically designed for individuals with sensitive skin, such as hypoallergenic cleansers and baby care products.

In some natural and fluoride-free toothpaste formulations, Disodium Cocoamphodiacetate may be used to enhance foaming and improve the overall texture of the toothpaste.
Disodium Cocoamphodiacetate can also be found in men's beard shampoos and cleansers to help cleanse and soften facial hair.
Disodium cocoamphodiacetate allows to make “frequent use” detergents and is compatible with all types of surfactants, anionic, amphoteric and non-ionic.

Disodium cocoamphodiacetate often used in delicate and creamy cleansers for sensitive skin and frizzy hair.
Very delicate products thanks to its high skin tolerability even in case of contact with mucous membranes (face gel, formulas for sensitive skin).
Disodium Cocoamphodiacetate can be incorporated into makeup brush cleaners and tool sanitizers to effectively remove makeup residues and bacteria from brushes and tools.

Disodium Cocoamphodiacetate can be used as a gentle cleansing agent.
Disodium cocoamphodiacetate helps in easy removal of the mask without excessive rubbing or pulling on the skin.
Due to its versatility and mildness, Disodium Cocoamphodiacetate is often included in travel-sized toiletries, including mini shampoos, conditioners, and body washes, for convenience when on the go.

Some pet shampoos use Disodium Cocoamphodiacetate as a mild cleansing agent for pets, ensuring gentle and effective cleaning without irritating the animal's skin or fur.
In medicated skincare products, such as those containing acne-fighting ingredients, Disodium Cocoamphodiacetate can serve as a gentle base for the active ingredients, ensuring they are delivered effectively to the skin.
Disodium Cocoamphodiacetate is used in foaming hand soaps to create a creamy and foamy lather that effectively cleanses the hands.

In some exfoliating scrubs and cleansers, Disodium Cocoamphodiacetate can be used alongside exfoliating particles to provide a gentle cleansing and exfoliating action.
Disodium cocoamphodiacetate can also be found in natural and organic cosmetic products, as it is derived from coconut oil and is considered a more eco-friendly and mild alternative to some synthetic surfactants.

In certain hair conditioners and detangling products, Disodium Cocoamphodiacetate may be used to enhance the overall product's texture and spreadability.
Disodium cocoamphodiacetateis sometimes included in eye makeup removers designed for sensitive eyes to remove mascara, eyeliner, and eyeshadow without causing irritation.
Disodium Cocoamphodiacetate can be found in pre-moistened cleansing wipes, which are convenient for quick cleansing and makeup removal.

Safety Profile:
While Disodium Cocoamphodiacetate is considered mild, it can still cause eye irritation if it comes into direct contact with the eyes.
Manufacturers typically formulate products containing this ingredient to minimize the risk of eye irritation, but it's essential to avoid getting the product in eyes and to rinse thoroughly if it does happen.

Although rare, some individuals may be sensitive or allergic to specific ingredients in cosmetics, including Disodium Cocoamphodiacetate.
The safety and effectiveness of products containing Disodium Cocoamphodiacetate depend on the overall formulation.
Disodium cocoamphodiacetate's crucial to consider the entire ingredient list and follow the manufacturer's instructions for use.

Environmental Impact:
While Disodium Cocoamphodiacetate is generally biodegradable, its environmental impact can depend on factors such as concentration, usage, and disposal.
Disodium cocoamphodiacetate's a good practice to use products containing this ingredient responsibly and follow any disposal recommendations on the product label.

Synonyms
DISODIUM COCOAMPHODIACETATE
68650-39-5
AMPHOLAK XCO-30
AMPHOSOL 2C
COCOAMPHOCARBOXYGLYCINATE
COCOAMPHODIACETATE [VANDF]
CRODATERIC CDA 40
DISODIUM COCOAMPHODIACETATE [II]
DISODIUM COCOAMPHODIACETATE [INCI]
DISODIUM N-COCOYL-N-CARBOXYMETHOXYETHYL-N-CARBOXYMETHYLETHYLENEDIAMINE
EMPIGEN CDR40
MACKAM 2C
18L9G3U51M
DISODIUM COCOYL GLUTAMATE
L-glutamic acid; N-coco acyl derivs monosodium salts;L- glutamic acid, mixed N-coco acyl and N-oleoyl derivs cas no: 68187-32-6
DISODIUM COCOYL GLUTAMATE
The chemical formula of Disodium Cocoyl Glutamate is C5H7NNa2O4.
Disodium cocoyl glutamate is a great cleansing ingredient as it is mild and good for sensitive skin.


CAS Number: 68187-30-4
EC Number: 269-085-1
Chem/IUPAC Name: L-Glutamic acid, N-coco acyl derivs., disodium salts
Molecular Formula: C5H7NNa2O4



SYNONYMS:
Disodium glutamate, Sodium L-glutamate, Sodium glutamate, 16690-92-9, Disodium L-glutamate, Disodium cocoyl glutamate, L-Glutamic acid disodium salt, 68187-30-4, disodium;(2S)-2-aminopentanedioate, UNII-MBK0CP8F5A, MBK0CP8F5A, H0US799L9M, EINECS 269-085-1, Accent, EC 269-085-1, L-GLUTAMIC ACID SODIUM, L-Glutamic acid, disodium salt, UNII-H0US799L9M, Glutamic acid, disodium salt, L-, disodium (2S)-2-aminopentanedioate, EINECS 240-733-5, glutamic acid sodium salt, DISODIUM S-GLUTAMATE, SCHEMBL18880, DISODIUM GLUTAMATE, L-, CHEBI:91250, DTXSID00894749, GLUTAMIC ACID DISODIUM SALT, L(+)-GLUTAMIC ACID DISODIUM SALT, NS00085269, NS00086898, L-GLUTAMIC ACID, SODIUM SALT (1:2), Q27887092, L-Glutamic acid, N-coco acyl derivs, disodium salts, Disodium cocoyl glutamate;L-Glutamic acid, N-coco acyl derivs., disodium salt, L-Glutamic acid, N-cocoacyl derives, monosodium salts; N-Cocoyl-L-glutamicacid, monosodium salt, Glutamyl,



Disodium cocoyl glutamate is a great cleansing ingredient as it is mild and good for sensitive skin.
Disodium cocoyl glutamate effectively picks up oil and dirt from the skin and hair to leave it clean.
Disodium cocoyl glutamate also produces a good amount of foam to make the product feel good and perform better.


Disodium cocoyl glutamate can be found in many personal care products such as shampoos, shower gels, scrubs and cleansers.
In its natural form, Disodium cocoyl glutamate appears as a white crystalline powder.
The chemical formula of Disodium Cocoyl Glutamate is C5H7NNa2O4.


Disodium cocoyl glutamate is a mild, biodegradable, anionic, amino acid-based surfactant.
Disodium cocoyl glutamate offers excellent emollient, moisturizing and conditioning capabilities.
Disodium cocoyl glutamate exhibits good decontamination, emulsification, solubilization, foam stabilization, rust prevention, corrosion inhibition, wetting and penetration abilities.


Disodium cocoyl glutamate offers hard water resistance and certain antistatic and bactericidal capabilities under acidic conditions.
Disodium cocoyl glutamate provides excellent compatibility with skin & hair, no allergic reaction, phototoxicity and has no acne-causing properties.
Disodium cocoyl glutamate has a shelf life of 24 months.


Disodium cocoyl glutamate may be synthetic or derived from plants or animals. Paula’s Choice does not use the animal-derived version.
Usage levels of Disodium cocoyl glutamate typically hover between 2.5–5%.
Disodium cocoyl glutamate is a mild surfactant with very good cleaning properties and a very good foam performance.


Disodium cocoyl glutamate is very suitable for cleaning sensitive skin.
Vegetable oils and sugar are the raw materials that Disodium cocoyl glutamate is used for the production of this detergent.
Disodium cocoyl glutamate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Disodium cocoyl glutamate is a vegetable surfactant derived from coconut or palm kernel oil.
Disodium cocoyl glutamate is a mild cleanser and surfactant which is used as a foaming agent in shampoos, shaving foam, toothpaste, and other skincare products.


Disodium cocoyl glutamate is extremely beneficial for people having sensitive skin and mild skin issues.
Disodium cocoyl glutamate is a good surfactant for Sulfate-free, EO-free formulations
Disodium cocoyl glutamate is an amino acid surfactant synthesized by acylation and neutralization reaction of sodium glutamate (corn fermentation) and fatty acid.


Disodium cocoyl glutamate is a colorless or light yellow transparent liquid with good low temperature stability.
Disodium cocoyl glutamate has a risk factor of 1, which is relatively safe and can be used with confidence.
Disodium cocoyl glutamate generally has no effect on pregnant women and has no acne-causing properties.


Disodium cocoyl glutamate is a natural surfactant approved by ECOCERT, NaTrue and BDIH for use in natural cosmetics.
Disodium cocoyl glutamate is an anionic surfactant based on the amino acid glutamic acid and coconut oil acids.
Disodium cocoyl glutamate contains about 25% active ingredient with a pH value of about 9, which should be adjusted in the final product.


Disodium cocoyl glutamate helps to combine the aqueous and oil phase of the product.
Disodium cocoyl glutamate is suitable for sensitive and children's skin as well as scalp with seborrhea.
Particularly suitable for children as Disodium cocoyl glutamate does not sting the eyes.


Disodium cocoyl glutamate is a gentle and eco-friendly surfactant that's derived from coconut oil and glutamic acid (natural amino acid).
Disodium cocoyl glutamate's a versatile ingredient that is used in a wide range of personal care products.
Disodium cocoyl glutamate is of high quality and purity, ensuring that you get the best results for your skin and the environment.


Disodium cocoyl glutamate is a natural surfactant (foaming ingredient), derived from coconut oil, corn and fruit sugars.
Disodium cocoyl glutamate is known to be safe and natural for shampoos, which is the reason we decided to use it in our sulfatte free shampoo bases.
Disodium cocoyl glutamate is a chemical compound, disodium salt of L-glutamic acid.


Disodium cocoyl glutamate is produced industrially from vegetable sources such as oils and sugar.
The name describes the structure of Disodium cocoyl glutamate:
Disodium indicates that there are two sodium ions in Disodium cocoyl glutamate, which are negatively charged and help to increase the solubility of the compound in water.


Cocoyl is derived from "coconut oil", indicating that the compound is derived from fatty acids found in coconut oil.
The "coco" of the molecule is a fatty acid radical (R-CO-), where R represents a long chain of carbon and hydrogen atoms.
Glutamate refers to glutamic acid, an amino acid, from which this part of the molecule is derived.


In Disodium cocoyl glutamate, the amino group of glutamic acid was replaced by the coconut group, forming an amide bond.
The "Glutamate" part of the name indicates that the compound is a salt or an ester of glutamic acid.
Glutamate DC100 is a powder form of Disodium Cocoyl Glutamate. Disodium cocoyl glutamate has a salt concentration with a maximum of 16%.


Disodium cocoyl glutamate is a high foaming, anionic, amino acid surfactant.
Disodium cocoyl glutamate's a natural product based on the amino acid glutamic acid.
Disodium cocoyl glutamate has great biodegradability and has reasonable tolerance to both salt and hard water.


Disodium cocoyl glutamate is a mild surfactant that will leave the skin feeling extremely pleasant and silky.
Disodium cocoyl glutamate is easy to use and easy to store and has a shelf life of 24 months.
Disodium cocoyl glutamate is a clear, translucent, pleasant to use


Disodium cocoyl glutamate is free from all kinds of sulfate substances that irritate the scalp.
Disodium cocoyl glutamate provides high volume, thick and constant bubbles with water in all conditions, easy to rinse (saving water).
Disodium cocoyl glutamate has a pH in the range of 8.0-10.0, so it is necessary to adjust the pH of the formula to be in the weak acid range to be gentle on the skin With soft grades such as Citric Acid, Lactic Acid.


Disodium cocoyl glutamate is a glutamate-based, mild, anionic surfactant.
Disodium cocoyl glutamate has outstanding foam-boosting properties, providing a fine and creamy foam in combination with other surfactants.
Disodium cocoyl glutamate leaves a soft feeling on the skin during and after use.


Due to its conditioning properties on skin and hair, Disodium cocoyl glutamate is also suitable for haircare, providing lubricity, softness, and a silky feel to the hair.
Disodium cocoyl glutamate is a gentle ingredient made using natural, renewable ingredients


Disodium cocoyl glutamate is among the mildest amino acid tensides from natural, renewable materials.
Derived from coconut oil and fermented sugar, this gentle cleanser, Disodium cocoyl glutamate, has excellent cleansing and foaming properties is environmentally-friendly and is well-tolerated by sensitive and allergic skin types.


Disodium cocoyl glutamate is also Nature approved.
Disodium cocoyl glutamatects as a surfactant, foaming,conditioning and moisturizing agent.
Disodium cocoyl glutamate is an anionic, weakly acidic and a mild grade.


Disodium cocoyl glutamate has an excellent conditioning effect to the hair, leaving a silky feel without a dry, coarse feel.
Disodium cocoyl glutamate leaves a non-sticky, soft and moisturized feeling on the skin without tautness.
Disodium cocoyl glutamate is a disodium salt of the coconut acid amide of glutamic acid.


Disodium cocoyl glutamate is a conjugate of coconut oil fatty acids and glutamic acid present in the collagen.
Disodium cocoyl glutamate is a mild anionic surfactant and detergent with excellent skin compatibility used in cleansing formulations based on mostly botanical ingredients.


Disodium cocoyl glutamate has been compared with a standard surfactant Sodium Laureth Sulfate (SLES) for a degreasing effect on the skin.
Results were interesting, both detergents notably decreased the sebum levels, but in the case of SLES, the sebum level increased again after the application break.


Disodium cocoyl glutamate showed a prolonged effect in preventing reactive seborrhoea.
So, Disodium cocoyl glutamate is an ideal botanical ingredient for face cleansing formulations that eliminate excess sebum and lessen conditions for the development of acne.


Intensive cleansing care can feel good - thanks to the gentle clean-rinsing.
Disodium cocoyl glutamate transforms skincare products into a new sensory experience: shower gels, liquid soaps, or facial cleansers for intensive cleansing that is exceptionally kind to the skin.


Disodium cocoyl glutamate is also dermatologically safe and has exceptional biodegradability (ecologically safe).
Simply the perfect finishing touch to any skincare formulation.
Disodium cocoyl glutamate is a multifunctional anionic surfactant with very good cleaning performance.


Disodium cocoyl glutamate reduces the absorption of anionic surfactants and thus prevents the skin from drying out, which is why it is excellently suited for sensitive and allergic skin and has an extremely low irritation potential.
Disodium cocoyl glutamate has a fine foam, excellent foaming properties and high foam stability.


Furthermore, Disodium cocoyl glutamate has good emulsifying properties, is very environmentally friendly and biodegradable.
Free fatty acids are removed by a physical process.
Disodium cocoyl glutamate is a gentle cleansing ingredient derived from coconut.


Disodium cocoyl glutamate is generally well tolerated, even in those with sensitive skin.
Disodium cocoyl glutamate has been ruled safe as used in cosmetics.
Disodium cocoyl glutamate’s an anionic surfactant, which means the water-loving end of the molecule has a negative charge which helps lift and suspend soil from skin.



USES and APPLICATIONS of DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate is mainly used as a foam booster and cleanser in skin care products.
Disodium cocoyl glutamate is used in baby cleansing products, facial cleanser, bath lotion, post-dyed shampoo, cleansing gel, foam cleanser, oral products.
Skin Cleansing Products: Disodium cocoyl glutamate is used in cleansers, liquid soaps, and facial cleaning products due to its soothing and moisturizing properties, making it suitable even for sensitive skins.


Hair Care Products: Found in shampoos and conditioners where Disodium cocoyl glutamate acts as a conditioning agent, aiding in gently cleansing hair and scalp.
Surfactant - Cleansing agent uses of Disodium cocoyl glutamate:


Cosmetic products used to cleanse the skin utilise the surface-active action that produces a lowering of the surface tension of the stratum corneum, facilitating the removal of dirt and impurities.
Cleansing agent uses of Disodium cocoyl glutamate: Ingredient that cleanses skin without exploiting the surface-active properties that produce a lowering of the surface tension of the stratum corneum.


The dosage as the main surfactant of Disodium cocoyl glutamate is normally 8.0%-15.0%, as auxiliary surfactant 1.0%-6.0%.
Disodium cocoyl glutamate is mainly used as a foam booster and cleanser in skin care products.
Disodium cocoyl glutamate is very suitable for formulating non-sulfate system formulations.


Disodium cocoyl glutamate can be widely used in personal care including cleansing, shampoo, and shower gel.
Disodium cocoyl glutamate is used in the following products: washing & cleaning products and cosmetics and personal care products.
Other release to the environment of Disodium cocoyl glutamate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


Disodium cocoyl glutamate is used in the following products: washing & cleaning products, cosmetics and personal care products, inks and toners, leather treatment products and paper chemicals and dyes.
Disodium cocoyl glutamate is used in the following areas: formulation of mixtures and/or re-packaging.


Other release to the environment of Disodium cocoyl glutamate is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Disodium cocoyl glutamate is used in the following products: cosmetics and personal care products, washing & cleaning products, inks and toners, leather treatment products and paper chemicals and dyes.


Release to the environment of Disodium cocoyl glutamate can occur from industrial use: formulation of mixtures.
Disodium cocoyl glutamate is used in the following products: washing & cleaning products, inks and toners, leather treatment products and paper chemicals and dyes.


Disodium cocoyl glutamate is used in the following areas: formulation of mixtures and/or re-packaging.
Release to the environment of Disodium cocoyl glutamate can occur from industrial use: in processing aids at industrial sites.
Release to the environment of Disodium cocoyl glutamate can occur from industrial use: manufacturing of the substance.


Disodium cocoyl glutamate is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Disodium cocoyl glutamate is used in a range of products such as shampoos, toothpaste, liquid soaps, baby care formulations, feminine hygiene wash, contact lens cleaners, shaving preparations.


Because of its good adaptability to hard water, strong cleaning power, good wetting power, high biodegradability, and no allergic reaction and phototoxicity, Disodium cocoyl glutamate can be widely used in personal care and household care detergents.
Disodium cocoyl glutamate is mainly used in liquid products such as cleansing, shampoo, and shower gel.


Disodium cocoyl glutamate is mainly used as a foam booster, surfactant, and cleanser in skin care products.
Disodium cocoyl glutamate is usable in a wide pH range even in weakly acidic in a solution.
Disodium cocoyl glutamate is used in sulfate-free products, body shampoos, hair shampoos, soap bars, facial cleansing gel, facial cleansing foam, make-up cleansing and make-up cleansing.


Disodium cocoyl glutamate can be used in shampoo formulas, liquid soaps, facial cleansing products. or any cleaning products who want tenderness and avoid sulfates
Disodium cocoyl glutamate is a gentle detergent (sulfate-free), able to provide good foam, affordable price, able to provide a clear formula.


Good cleaning performance, Disodium cocoyl glutamate can be used as the main detergent in the formula (primary surfactant), commonly used in toothpaste.
Disodium cocoyl glutamate serves to make foam bubbles well.
Disodium cocoyl glutamate use is really wide.


Disodium cocoyl glutamate is used in shampoos, washing powders, bath foam, lotions and cleansers, baby soaps, foundation creams, etc.
Disodium cocoyl glutamate can be used alone or together with other surfactants.
Disodium cocoyl glutamate has a high degree of biodegradability and is often used in facial cleansers, foaming shampoos, body wash or shaving creams.


Disodium cocoyl glutamate is often used in a blend with sodium cocoyl glutamate.
When making solid cleaning products, carefully mix Disodium cocoyl glutamate with the melted butters and the like that are usually contained in such a product.


When used and stored, Disodium cocoyl glutamate may turn darker, beige, pink and yellow-brown.
The same applies to what is made of Disodium cocoyl glutamate.
Disodium cocoyl glutamate is a mild, biodegradable, anionic, amino acid-based surfactant.


Disodium cocoyl glutamate offers excellent emollient, moisturizing and conditioning capabilities.
Disodium cocoyl glutamate exhibits good decontamination, emulsification, solubilization, foam stabilization, rust prevention, corrosion inhibition, wetting and penetration abilities.


Disodium cocoyl glutamate offers hard water resistance and certain antistatic and bactericidal capabilities under acidic conditions.
Disodium cocoyl glutamate provides excellent compatibility with skin & hair, no allergic reaction, phototoxicity and has no acne-causing properties.
Disodium cocoyl glutamate is a gentle cleansing ingredient derived from coconut.


Disodium cocoyl glutamate is generally well tolerated, even in those with sensitive skin.
Disodium cocoyl glutamate has been ruled safe as used in cosmetics.
Disodium cocoyl glutamate’s an anionic surfactant, which means the water-loving end of the molecule has a negative charge which helps lift and suspend soil from skin.


Disodium cocoyl glutamate may be synthetic or derived from plants or animals.
Usage levels of Disodium cocoyl glutamate typically hover between 2.5–5%.
Disodium cocoyl glutamate is an anionic surfactant, or surface active agent, that is prepared by the condensation of naturally originated amino acid and cocoyl chloride.


Disodium cocoyl glutamate is a surfactant in solid form, a cleansing substance for use in, for example, washing tablets, shampoo, shower gel and the like.
Disodium cocoyl glutamate is a gentle anionic surfactant that is perfectly suited to the formulation dedicated to sensitive skin.
Disodium cocoyl glutamate is authorised for use in organic products.


Disodium cocoyl glutamate is a vegetable surfactant derived from coconut or palm kernel oil and corn glucose.
This cleansing agent, Disodium cocoyl glutamate, is often used in a blend with sodium cocoyl glutamate.
Disodium cocoyl glutamate is very suitable for formulating non-sulfate system formulations.


Disodium cocoyl glutamate can be widely used in personal care including cleansing, shampoo, and shower gel.
Disodium cocoyl glutamate has a shelf life of 24 months.
Disodium cocoyl glutamate is a mild cleanser and surfactant which is used as a foaming agent in shampoos, shaving foam, toothpaste, and other skincare products.


Disodium cocoyl glutamate is extremely beneficial for people having sensitive skin and mild skin issues.
In addition to being an excellent cleaner and foam generator, Disodium cocoyl glutamate is also eco-friendly.
Disodium cocoyl glutamate is a disotic salt (salt containing two sodium atoms per molecule) of the amide (organic compound derived from a carboxylic acid) of glutamic acid and coconut acid.


Lots of information for just one ingredient, the science can sometimes be complex!
Disodium cocoyl glutamate has two major properties, those of acting as a cleaning active ingredient and as a surfactant in a formula.
This gentle agent effectively cleanses the skin and hair, while ridding it of sebum or dirt.


Disodium cocoyl glutamate also generates a large quantity of foam, giving the product containing it a recognized effectiveness combined with great pleasure of use.
Often found in shower gels, exfoliants and cleansers, we have added Disodium cocoyl glutamate to solid shampoo to perfectly combine effectiveness and well-being.


-For liquid applications of Disodium cocoyl glutamate:
mix Disodium cocoyl glutamate with the other ingredients of the formula and you're done.
Heating is not necessary, but can promote dissolution of the substance.


-Cosmetics uses of Disodium cocoyl glutamate:
Disodium cocoyl glutamate is a surfactant, an anionic cleaning agent with a foaming agent function.
Disodium cocoyl glutamate is used in cleansing gels, shampoos and other body care products.


-Cosmetic Industry uses of Disodium cocoyl glutamate:
Disodium Cocoyl Glutamate is a mild surfactant derived from coconut fatty acids and glutamic acid.
Disodium cocoyl glutamate is known for its cleansing and foaming properties.



USES OF DISODIUM COCOYL GLUTAMATE:
*Gentle Cleansing:
Disodium cocoyl glutamate is a mild and gentle surfactant that effectively cleanses the skin without causing irritation or dryness. Disodium cocoyl glutamate's perfect for use in facial cleansers, body washes, and shampoos.

*Suitable for Sensitive Skin:
Disodium cocoyl glutamate is non-irritating and non-toxic, making it suitable for use in products for sensitive skin.
Disodium cocoyl glutamate's a gentle alternative to harsh synthetic surfactants that can cause skin irritation and allergies.

*Biodegradable and Eco-Friendly:
Disodium cocoyl glutamate is a biodegradable and eco-friendly surfactant that's safe for the environment.
Disodium cocoyl glutamate's made from renewable resources and breaks down easily in wastewater treatment systems.

Disodium cocoyl glutamate is a natural and effective ingredient that's perfect for use in a wide range of personal care products. Whether you're looking for a gentle cleanser or a sulfate free shampoo, Disodium cocoyl glutamate is the perfect choice for you. Try Disodium cocoyl glutamate today and experience the natural benefits of this amazing surfactant!



PROPERTIES AND AREAS OF USE OF DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate is a completely natural, gentle anionic surfactant of plant origin.
Disodium cocoyl glutamate complies with Cosmos and Ecocert standards.

Disodium cocoyl glutamate is biodegradable.
With its excellent conditioning, antistatic, high detergent and foaming properties, Disodium cocoyl glutamate can be used in products such as shampoo, bubble bath and shower gel.

Disodium cocoyl glutamate helps create a creamy and dense foam.
Since it is a gentle surfactant, it provides tear-free, safe and high-performance results, including for very sensitive skin and baby products.
Since its viscosity is low, Disodium cocoyl glutamate allows easy application and homogenization during production.



WHAT IS DISODIUM COCOYL GLUTAMATE USED FOR?
Disodium Cocoyl Glutamate is an effective cleansing ingredient that can be found in many skin and hair care products.
Disodium cocoyl glutamate is mild in nature and suits all the skin types, even sensitive ones.

*Skin care:
In skin care products, Disodium cocoyl glutamate is added because it works well with both oil based and water-based ingredients.
Disodium cocoyl glutamate mixes the other ingredients well and prevents them from separating.
Moreover, Disodium cocoyl glutamate does not dry out the skin and leaves it feeling moisturized instead.

*Hair care:
Disodium cocoyl glutamate effectively picks up oil and dirt from the surface of the scalp and gently washes it off.
Disodium cocoyl glutamate is not harsh on the hair and thus does not strip it off of all its moisture while cleaning.



ORIGIN OF DISODIUM COCOYL GLUTAMATE:
Disodium Cocoyl Glutamate can be natural or synthetic based on where it is derived from.
Naturally, Disodium cocoyl glutamate comes from coconut or palm kernels.
This coconut or palm kernel derivative is combined with monosodium glutamate to produce Disodium Cocoyl Glutamate.
Disodium cocoyl glutamate can also sometimes be made from animal sources.



WHAT DOES DISODIUM COCOYL GLUTAMATE DO IN A FORMULATION?
*Cleansing
*Foaming
*Moisturising
*Surfactant



SAFETY PROFILE OF DISODIUM COCOYL GLUTAMATE:
Disodium Cocoyl Glutamate is a safe ingredient and does not adversely impact the surface of the skin or hair.
However, as is the case with all the ingredients, a patch test should not be skipped.
The usage percentage of Disodium cocoyl glutamate recommended for personal care products is 2.5 - 5%.

Disodium cocoyl glutamate is a mild ingredient and is good for sensitive skin.
Disodium cocoyl glutamate is non comedogenic and does not clog the pores or cause acne.
Lastly, Disodium cocoyl glutamate can or cannot be vegan depending on the source that it is derived from.



ALTERNATIVES OF DISODIUM COCOYL GLUTAMATE:
*SODIUM COCOSULFATE,
*SODIUM LAURETH SULFATE



BENEFITS OF DISODIUM COCOYL GLUTAMATE:
*Mild Cleansing:
Sodium Cocoyl Glutamate is a surfactant that effectively removes dirt, bacteria, and debris from the teeth and gums without causing irritation or excessive dryness.

*Gentle Foaming:
Disodium cocoyl glutamate provides a gentle foaming action that helps to dislodge plaque and food particles, promoting better oral hygiene.

*Natural Ingredient:
Disodium cocoyl glutamate is derived from natural sources, making it a preferable alternative to synthetic or harsh chemicals commonly found in oral care products.

*Moisturizing Effect:
Disodium cocoyl glutamate has moisturizing properties that help to prevent dryness and maintain the natural moisture balance of the mouth.

*Non-Toxic:
Sodium Cocoyl Glutamate is generally considered safe and non-toxic, making it suitable for individuals with sensitive teeth or gums.



FUNCTIONS OF DISODIUM COCOYL GLUTAMATE:
*Surfactant
*Cleansing agent
*Sebum regulator
*Detergent



THE SYNTHESIS PROCESS OF DISODIUM COCOYL GLUTAMATE:
The synthesis process takes place in several stages:

*Extraction of oil from coconuts:

**Hydrolysis.
Coconut oil undergoes a process called hydrolysis, where it is broken down into its fatty acids and glycerol components.

**Fermentation.
Fatty acids are fermented with specific types of bacteria to produce glutamic acid.

**Neutralization.
Glutamic acid is neutralized with sodium hydroxide to form sodium glutamate.

**Esterification.
Sodium glutamate is then reacted with coconut fatty acids in a process called esterification to form coconut glutamate.

**Neutralization.
Finally, coconut glutamate is neutralized with sodium hydroxide to form Disodium Cocoyl Glutamate.
Disodium cocoyl glutamate occurs as a colourless or yellowish liquid.



DISODIUM COCOYL GLUTAMATE AT A GLANCE:
*Gentle cleansing ingredient
*Derived from coconut
*Considered gentle enough even for sensitive skin
*Ruled safe as used in cosmetics



EXTRACTION OF DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate is obtained from coconut oil and fermented sugar.
This surfactant, Disodium cocoyl glutamate, is one of the most gentle and respectful to the skin so it is tolerated by all types of skins.



PROPERTIES OF DISODIUM COCOYL GLUTAMATE:
*Well compatible with ionic, nonionic or/and amphoteric surfactants
*Mild skin cleanser and make skin appear the supple and moist feeling
*Mild hair cleanser without dry and rough
*Well used in shampoo, facial cleanser, shower gel, and baby products, etc.



BENEFITS AND APPLICATIONS OF DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate is highly effective, keeping in mind it is gentle and mild to the skin.
Disodium cocoyl glutamate is an excellent cleanser and foam booster that will increase the effectiveness and texture of your DIY formulation.

Disodium cocoyl glutamate will give your formulation a rich and creamy form and will make the bubbles thick and fluffy.
Being a natural and organic product, Disodium cocoyl glutamate works extremely well for people with pH-sensitive skin.
Disodium cocoyl glutamate is a good alternative to sulfate products, hence making your formulation sulfate-free.

Disodium cocoyl glutamate works well with hard water.
Disodium cocoyl glutamate can be incorporated into your solid or cream products without heating the solution.



HOW DISODIUM COCOYL GLUTAMATE WORKS:
Disodium cocoyl glutamate works by removing the dirt and impurities mixed with oils in your skin and hair.
Disodium cocoyl glutamate works by allowing the mixing of these oils and water, which can now be easily rinsed away, hence cleansing the desired area.



CONCENTRATION AND SOLUBILITY OF DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate is recommended that it should be used at a concentration of 30% for best results.
Disodium cocoyl glutamate is soluble in water and alcohols and insoluble in volatile oils.



HOW TO USE DISODIUM COCOYL GLUTAMATE:
Mix Disodium cocoyl glutamate with water in the recommended concentration and stir until a homogeneous mixture is created.
Add other surfactant and enhancing ingredients like essential oils, depending on your product and need, and mix properly.
Add this mixture to the warm base of the product and stir until the desired thickness and texture are obtained.



FUNCTIONS OF DISODIUM COCOYL GLUTAMATE:
*Cleansing :
Disodium cocoyl glutamate helps to keep a clean surface
*Surfactant :
Disodium cocoyl glutamate reduces the surface tension of cosmetics and contributes to the even distribution of the product when it is used.



BENEFITS OF DISODIUM COCOYL GLUTAMATE:
-Mild to the skin and eyes
-Suitable for sensitive Skin
-Environmentally friendly with good biodegradability
-Sulphate-free
-Produces a fine-bubbled, creamy foam
-Good cleansing properties, even in hard water
-Free of preservatives and perfumes
-Good performance at pH 5.5



SUSTAINABILITY OF DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate is largely made from renewable plant-based substances, such as coconut oil, corn and sugar.
That makes Disodium cocoyl glutamate more sustainable than SCI.
Disodium cocoyl glutamate is completely degradable in the environment.



USAGE RATE OF DISODIUM COCOYL GLUTAMATE:
Mix Disodium cocoyl glutamate with water at 20-40% for use as the primary surfactant and use at 5-20% for use as a secondary surfactant in the formulation (secondary surfactant with other primary detergents).



PROPERTIES OF DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate is a white to beige powder at room temperature.
Because Disodium cocoyl glutamate contains no water, the concentration of detergent active is approximately 100%.
Disodium cocoyl glutamate has a fairly long shelf life: store in a cool, dry, dark place and in a tightly closed container.
Particularly dry is important, DO NOT store Disodium cocoyl glutamate in a refrigerator.



FUNCTIONS OF DISODIUM COCOYL GLUTAMATE IN COSMETIC PRODUCTS:
*CLEANSING
Disodium cocoyl glutamate cleans skin, hair or teeth

*SURFACTANT - CLEANSING
Surface-active agent to clean skin, hair and / or teeth



BENEFITS OF DISODIUM COCOYL GLUTAMATE:
*Natural and biodegradable
*Powder form means no unnecessary transport and storage of water
*High foaming, great performance in acidic conditions
*Mild surfactant that imparts a pleasant skin feel
*COSMOS
*Easy to use



EFFECTS AND APPLICATIONS OF DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate belongs to the amino acid surfactant, which has good decontamination and foaming capabilities, and has certain antistatic and bactericidal capabilities under acidic conditions.
The ingredients are relatively mild and have good compatibility with the skin.



WHY DO WE USE DISODIUM COCOYL GLUTAMATE IN FORMULATIONS?
Disodium cocoyl glutamate is a very gentle foaming agent which is used to make products for face, body, hair and hands.
As it is made with amino acid, Disodium cocoyl glutamate has a very good affinity with (keratin) the skin and hair leaving them with a pleasant silky feeling.
Disodium cocoyl glutamate also adds some conditioning to the hair, so the combing is easier (wet and dry).



STRENGHTS OF DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate doesn‘t dry out the skin like other surfactants, so it is considered very mild.
Disodium cocoyl glutamate has a good foamimg power and is resistant to hard water.
The bubbles are fine and creamy, similar to Disodium cocoyl glutamate.



WHAT DOES DISODIUM COCOYL GLUTAMATE DO IN A FORMULATIONS?
*Cleansing
*Emulsifying
*Foaming
*Smoothing
*Surfactant



PROPERTIES OF DISODIUM COCOYL GLUTAMATE:
*Derived from coco / palm kernel fatty acid
*Primary / secondary anionic surfactant
*Compatible with anionic, non-ionic and amphoteric surfactants
*Stable over entire pH range
*Excellent foam profile
*Hard water tolerant
*Good cleansing agent for skin and hair
*Suitable for transparent / opaque / pearly formulations
*Environmental friendly, highly biodegradable



BENEFITS OF DISODIUM COCOYL GLUTAMATE:
*Natural and biodegradable
*Mild, sulfate free, high active
*High foaming, great performance in acidic conditions
*Mild surfactant that imparts a pleasant skin feel
*Hard water tolerant
*Stable over entire pH range
*Compatible with anionic, non-ionic and amphoteric surfactants
*Exceptionally mild



NOTES OF DISODIUM COCOYL GLUTAMATE:
Disodium cocoyl glutamate can be thickened using with lauryl glucoside, gums.
Disodium cocoyl glutamate is extremely beneficial for people having sensitive skin and mild skin issues.

Disodium cocoyl glutamate is used for external use only.
Product has tendency to crystallize / solidify and become non - pourable, if stored at < - 5°C.

If it solidifies, it is recommended to increase the temperature of Disodium cocoyl glutamate maximum to 55°C by heating the ISO containers with hot water jacket.
Post melting to liquid, entire mass has to be made homogeneous before use.



PERFORMANCE CHARACTERISTICS OF DISODIUM COCOYL GLUTAMATE:
1.mild and soft
2.Good self thickening ability
3.The foam is abundant with little irritation.
4.Bear natural coconut oil smell.
5.Obviously reducing the degreasing power of soap base.
6.Improving the foam shape of soap and the feeling of tightness after washing.



PHYSICAL and CHEMICAL PROPERTIES of DISODIUM COCOYL GLUTAMATE:
Boiling Point: 333°C
pH: 6.0-7.0
Solubility: Soluble in water
Physical Structure: Light colored liquid
CAS No: 68187-30-4 / 68187-32-6
Recommended pH range: 7-8
Solubility: Water
Function: Surfactant
Appearance: White crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 333.00 to 334.00°C @ 760.00 mm Hg (est)
Vapor Pressure: 0.000025 mmHg @ 25.00°C (est)
Flash Point: 312.00°F TCC (155.70°C) (est)
logP (o/w): -1.435 (est)

Soluble in: Water, 1e+006 mg/L @ 25°C (est)
Molecular Weight: 191.09412856
Formula: C5H7NNa2O4
Appearance (25°C): Clear to slightly turbid liquid
Total Solid: 28.0% ~ 32.0%
Colour (APHA): Not more than 150
Sodium Chloride: 3.0% ~ 6.0%
Chemical Name: Disodium Cocoyl Glutamate
CAS No.: 68187-30-4
Molecular Formula: C5H7NNa2O4
Molecular Weight: 191.09292
Appearance: Colorless or yellowish liquid
Assay: 28-30%

Molecular Weight: 191.09 g/mol
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 2
Exact Mass: 191.01704627 g/mol
Monoisotopic Mass: 191.01704627 g/mol
Topological Polar Surface Area: 106 Ų
Heavy Atom Count: 12
Formal Charge: 0
Complexity: 134
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes



FIRST AID MEASURES of DISODIUM COCOYL GLUTAMATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of DISODIUM COCOYL GLUTAMATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of DISODIUM COCOYL GLUTAMATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of DISODIUM COCOYL GLUTAMATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of DISODIUM COCOYL GLUTAMATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of DISODIUM COCOYL GLUTAMATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


DISODIUM DIPHOSPHATE (E450)
Disodium diphosphate (E450) or sodium acid pyrophosphate (SAPP) is an inorganic compound with the chemical formula Na2H2P2O7.
Disodium diphosphate (E450) consists of sodium cations (Na+) and dihydrogen pyrophosphate anions (H2P2O2−7).
Disodium diphosphate (E450) is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.

CAS: 7758-16-9
MF: H5NaO7P2
MW: 201.97
EINECS: 231-835-0

Synonyms
DisodiuM pytophospha;TwosodiuM pyrophosphatetwo hydrogen;Amyloid Precursor Protein β, Secreted;ANTI-DSPP (N-TERM) antibody produced in rabbit;Dentin sialophosphoprotein;SodiuM pyrophosphate dibasic practical grade;SODIUM PYROPHOSPHATE DIBASIC BIOULTR;Food Grade Sodium;Acid Pyrophosphate;7758-16-9;Disodium diphosphate;Sodium acid pyrophosphate;Disodium dihydrogen pyrophosphate;DISODIUM PYROPHOSPHATE;H5WVD9LZUD;disodium;[hydroxy(oxido)phosphoryl] hydrogen phosphate;MFCD00014246;Disodium acid pyrophosphate;Dinatriumpyrophosphat;Disodiumpytophosphate;Dinatriumpyrophosphat [German];Disodium dihydrogen diphosphate;Disodium dihydrogenpyrophosphate;HSDB 377;Pyrophosphoric acid, disodium salt;UNII-H5WVD9LZUD;Sodium pyrophosphate (Na2H2P2O7);EINECS 231-835-0;Sodium diphosphate dibasic;disodium pyrophosphate 2-;disodium hydrogen (hydrogen phosphonatooxy)phosphonate;Grahamsches salz;Glassy sodium phosphate;DSSTox_CID_8842;sodium dihydrogendiphosphate;EC 231-835-0;DSSTox_RID_78658;DSSTox_GSID_28842;SODIUMACIDPYROPHOSPHATE;Sodium pyrophosphate, dibasic
;Sodium dihydrogen pyrophosphate;CHEMBL3184949;EINECS 272-808-3;Tox21_200813;DISODIUM PYROPHOSPHATE [HSDB];DISODIUM PYROPHOSPHATE [INCI];DISODIUM PYROPHOSPHATE [VANDF];AKOS015916169;AKOS024418779;SODIUM ACID PYROPHOSPHATE [MI];Diphosphoric acid, sodium salt (1:2);SODIUM ACID PYROPHOSPHATE [FCC];NCGC00258367-01;SODIUM ACID PYROPHOSPHATE [VANDF];CAS-68915-31-1;di-sodium dihydrogen pyrophosphate anhydrous

When crystallized from water, Disodium diphosphate (E450) forms a hexahydrate, but it dehydrates above room temperature.
Disodium diphosphate (E450) is a polyvalent anion with a high affinity for polyvalent cations, e.g. Ca2+.
Disodium diphosphate (E450) is produced by heating sodium dihydrogen phosphate:

2 NaH2PO4 → Na2H2P2O7 + H2O

Disodium diphosphate (E450) gene is mapped to human chromosome 21q21.3.
Disodium diphosphate (E450) encodes a integral membrane protein.
Disodium diphosphate (E450) is a soluble protein generated by sequential cleavage with α and γ secretase.
Disodium diphosphate (E450) is a chemical additive and preservative.
Disodium diphosphate (E450) has many aliases.
Disodium diphosphate (E450) also is known as disodium dihydrogen diphosphate, disodium dihydrogen pyrophosphate and disodium pyrophosphate.
Disodium diphosphate (E450) also has the name sodium acid pyrophosphate.
Disodium diphosphate (E450) is an odorless white powder and, because it has a valance of greater than two, it can bond to many other chemicals.
Disodium diphosphate (E450) is a white crystalline solid that has an anhydrous form.
Disodium diphosphate (E450) is used as a buffering agent and is also a substrate for film forming polymers.
Disodium diphosphate (E450) has been shown to have the ability to inhibit cell lysis in vitro, which may be due to its hydrophobic properties.
The surface methodology used for Disodium diphosphate (E450) included the use of a hydrophobic surface with water vapor, which helped to prevent the adsorption of proteins onto the surface of the product.
Disodium diphosphate (E450) has been shown to be an effective buffer at optimum concentrations, with no harmful effects on fetal bovine or neuronal cells.

Disodium diphosphate (E450) Chemical Properties
Melting point: decomposes 220℃ [MER06]
Density: (hexahydrate) 1.86
Vapor pressure: 0Pa at 20℃
Storage temp.: -70°C
Solubility H2O: 0.1 M at 20 °C, clear, colorless
Form: white powder
Color: White to Off-White
PH: 3.5-4.5 (20℃, 0.1M in H2O, freshly prepared)
Water Solubility: Fully miscible in water. Insoluble in alcohol and ammonia.
λmax: λ: 260 nm Amax: 0.11
λ: 280 nm Amax: 0.09
Merck: 13,8643
Stability: Stable.
InChI: InChI=1S/Na.H4O7P2.H/c;1-8(2,3)7-9(4,5)6;/h;(H2,1,2,3)(H2,4,5,6);
InChIKey: IQTFITJCETVNCI-UHFFFAOYSA-N
LogP: -3.420 (est)
CAS DataBase Reference: 7758-16-9(CAS DataBase Reference)
EPA Substance Registry System: Disodium diphosphate (E450) (7758-16-9)

Disodium dihydrogendiphosphate, Disodium diphosphate (E450), acidic sodium pyrophosphate, Na2H2P2O7, Mr 221.97, d 2.31.
Disodium diphosphate (E450)'s solubility in water is 13g Na2H2P2O7/100g H2O at 20 °C, and 20g at 80°C.
The pH of a 1% aqueous solution is 4.1.
The usual commercial product is the anhydrous, nonhygroscopic salt in powder form.
The hexahydrate, Na2H2P2O7.6H2O, d 1.85, crystallizes from aqueous solution below 27 °C.
Above this temperature, Disodium diphosphate (E450) is converted to the anhydrous form.

Disodium diphosphate (E450) is used as a (tropically stable) acid carrier in baking powder, for improvement of flow properties in flour, for pH regulation, and in dental care products for prevention of tartar formation.

Uses
Sodium Pyrophosphate is a leavening agent, preservative, sequestrant, and buffer which is mildly acidic with a ph of 4.1.
Disodium diphosphate (E450) is moderately soluble in water, with a solubility of 15 g in 100 ml at 25°c.
Disodium diphosphate (E450) is used in doughnuts and biscuits for its variable gas release rate during the mixing, bench action, and baking process.
Disodium diphosphate (E450) is used in baking powder as a leavening agent.
Disodium diphosphate (E450) is used in canned fish products to reduce the level of undesired struvite crystals (magnesium ammonium phosphate hexahydrate) by complexing the magnesium.
Disodium diphosphate (E450) is used to sequester metals in processed potatoes.
Disodium diphosphate (E450) is also termed sapp, sodium acid pyrophosphate, acid sodium pyrophosphate, disodium diphosphate, and disodium dihydrogen pyrophosphate.
Sodium Pyrophosphate Dibasic is anhydrous form, pyrophosphate salt used in buffers.
Disodium diphosphate (E450) is a buffering agent and a Lewis base, a base that gives away electrons, drawing it near to other compounds.
Disodium diphosphate (E450) neutralizes other substances.
Disodium diphosphate (E450) also has industrial uses.
Disodium diphosphate (E450) can remove iron stains and stabilize hydrogen peroxide.
Disodium diphosphate (E450) is used to clean the machine used in dairy farms.
Disodium diphosphate (E450) also is used to remove hair from pigs and feathers from poultry before they are led to slaughter.
Disodium diphosphate (E450) is used in making plastics, too.

Food uses
Disodium diphosphate (E450) is a popular leavening agent found in baking powders.
Disodium diphosphate (E450) combines with sodium bicarbonate to release carbon dioxide:

Na2H2P2O7 + NaHCO3 → Na3HP2O7 + CO2 + H2O
Disodium diphosphate (E450) is available in a variety of grades that affect the speed of its action.
Because the resulting phosphate residue has an off-taste, Disodium diphosphate (E450) is usually used in very sweet cakes which mask the off-taste.

Disodium diphosphate (E450) in baking powder, New Zealand, 1950s
Disodium diphosphate (E450) and other sodium and potassium polyphosphates are widely used in food processing; in the E number scheme, they are collectively designated as E450, with the disodium form designated as E450(a).
In the United States, Disodium diphosphate (E450) is classified as generally recognized as safe (GRAS) for food use.
In canned seafood, Disodium diphosphate (E450) is used to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.
Disodium diphosphate (E450) is an acid source for reaction with baking soda to leaven baked goods.
In baking powder, Disodium diphosphate (E450) is often labeled as food additive E450.
In cured meats, Disodium diphosphate (E450) speeds the conversion of sodium nitrite to nitrite (NO−2) by forming the nitrous acid (HONO) intermediate, and can improve water-holding capacity.
Disodium diphosphate (E450) is also found in frozen hash browns and other potato products, where it is used to keep the color of the potatoes from darkening.
Disodium diphosphate (E450) can leave a slightly bitter aftertaste in some products, but "the SAPP taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings."

Other uses
In leather treatment, Disodium diphosphate (E450) can be used to remove iron stains on hides during processing.
Disodium diphosphate (E450) can stabilize hydrogen peroxide solutions against reduction.
Disodium diphosphate (E450) can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.
When added to scalding water, Disodium diphosphate (E450) facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.
In petroleum production, Disodium diphosphate (E450) can be used as a dispersant in oil well drilling muds.
Disodium diphosphate (E450) is used in cat foods as a palatability additive.
Disodium diphosphate (E450) is used as a tartar control agent in toothpastes.

Preparation
Disodium diphosphate (E450) is produced from sodium dihydrogenmonophosphate by heating at 200-250℃:
Na2CO3+2H3PO4→2NaH2PO4+H2O+CO2↑
2NaH2PO4→Na2H2P2O7+H2O

Biochem/physiol Actions
Amyloid precursor protein α is an α-secretase-cleaved soluble protein that has been shown to have neuroprotective properties.
Disodium diphosphate (E450) is derived from amyloid precursor protein.
The protein consists of 612 amino acids.
Several G protein-coupled receptors are known to activate α-secretase-dependent processing of APP.
Disodium diphosphate (E450) has neuroprotective, neurogenic and neurotrophic functions.
Amyloid precursor protein a also stimulates gene expression and protein expression.
DISODIUM DISILICATE
EDTA, Disodium Salt Dihydrate; Ethylenediaminetetraacetic acid disodium salt dihydrate; Ethanediylbis(N-(carboxymethyl)glycine) disodium salt; Disodium dihydrogen ethylenediaminetetraacetate; Versene disodium salt; cas no: 139-33-3
DISODIUM EDTA
DISODIUM EDTA-COPPER N° CAS : 14025-15-1 Nom INCI : DISODIUM EDTA-COPPER Nom chimique : Disodium [[N,N'-ethylenebis[N-(carboxymethyl)glycinato]](4-)-N,N',O,O',ON,ON']cuprate(2-) N° EINECS/ELINCS : 237-864-5 Classification : EDTA Ses fonctions (INCI) Astringent : Permet de resserrer les pores de la peau Agent de chélation : Réagit et forme des complexes avec des ions métalliques qui pourraient affecter la stabilité et / ou l'apparence des produits cosmétiques
DISODIUM EDTA
Disodium edta is used in several industrial applications attributing to its high ability to bind to most of metal cations.
Disodium edta is produced as several salts, e.g. ethylenediaminetetra-acetic acid disodium salt (EDTAS).
Disodium edta salts are used as chelating agents in cosmetic formulations.

CAS: 139-33-3
MF: C10H14N2Na2O8
MW: 336.21
EINECS: 205-358-3

Disodium edta is a preservative, sequestrant, and stabilizer in foods.
Disodium edta is added to ascorbic acid-disodium benzoate containing soft drinks to mitigate the formation of benzene.
Disodium edta and its salts are used as a component in the production of food-contact paper and paperboard.
Disodium edta is permitted in the feed and drinking water of animals and/or for the treatment of food-producing animals.
In the textile industry, Disodium edta and its salts prevent metal ion impurities from changing colors of dyed products.

In the pulp and paper industry, Disodium edta and its salts inhibit the ability of metal ions from catalyzing the disproportionation of hydrogen peroxide (a typical bleaching agent).
Disodium edta is used in synthetic rubber manufacture.
Disodium edta is also used as a corrosion inhibitor to carbon steel in the industries.
As an anticoagulant, Disodium edta and tripotassium salts of EDTA are most commonly used.
An organic sodium salt that is the anhydrous form of the disodium salt of ethylenediaminetetraacetic acid (EDTA).

Disodium edta is a chelating agent that has been used in many scientific applications for decades.
Disodium edta is a synthetic compound composed of two sodium ions and one EDTA molecule.
Disodium edta is most commonly used in laboratory experiments to chelate metals and other ions from solution, and Disodium edta has also been used in medical treatments for heavy metal poisoning and other conditions.
Disodium edta is a salt of ethylenediaminetetraacetic acid (commonly known as EDTA).
In cosmetics, Disodium edta functions primarily as a chelating agent, meaning it prevents ingredients in a formula from binding with trace elements (mainly minerals) that can be present in water or other ingredients.
This action enhances the stability of cosmetics formulas and helps makes the job of preservatives easier since Disodium edta ingredients bond with mineral ions that microorganisms need to remain intact.
In addition to being used in makeup, skin care, and hair care products, disodium EDTA is also used as a food additive.

Disodium EDTA is in many products as a preservative, to stabilise it, or to enhance the foaming action.
Disodium edta’s also used as a chelating agent, which means it us used to precipitate out metals from the formulation (if tap water were used to make the formulation instead purified water, for example, and Disodium edta can bind with metals dissolved in your shower water).
Disodium EDTA (chemical formula - C10H16N2Na2O8) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in a product.
This white, water-soluble solid is widely used to bind to metal ions like iron and calcium ions and prevent the deterioration of cosmetics and personal care products.
Disodium EDTA thus enhances stability of cosmetics.
Disodium edetate occurs as a white crystalline, odorless powder with a slightly acidic taste.

Disodium edta Chemical Properties
Melting point: 248 °C (dec.)(lit.)
Boiling point: >100 °C
Density: 1.01 g/mL at 25 °C
Vapor pressure: 0Pa at 25℃
Storage temp.: 2-8°C
Solubility H2O: clear, colorless
Form: solution
Color: ≤5 (0.5 M)(APHA)
Odor: at 100.00?%. odorless
Water Solubility: Miscible with water.
BRN: 3822669
Stability: Hygroscopic
LogP: -4.3 at 25℃
CAS DataBase Reference: 139-33-3(CAS DataBase Reference)
EPA Substance Registry System: Disodium edta (139-33-3)

Uses
Disodium edta is an aminopolycarboxylic acid and a hexadentate ligand.
Disodium edta chelates with metal ions, especially with cations to form an octahedral complex.
Disodium edta is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia.
Disodium edta chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.
Disodium edta enhances the antibacterial activity of lysozyme.
Disodium edta used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.
Disodium edta chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.

Disodium edta is a preservative used in concentrations of 0.1 to 0.5 percent.
Disodium edta is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.
Disodium edta is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels.
A 1% solution has a ph of 4.3–4.7.
Disodium edta is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Disodium edta's function is comparable to that of disodium calcium edta.
Disodium edta is widely used in textile industry.
Usually applied to dissolve limescale.
Disodium edta is applied in textile industry, pulp and paper industry and also in chelation therapy.
In cosmetics, Disodium edta acts as a sequestering agent.

Disodium edta acts as a corrosion inhibitor to carbon steel in the industries.
Disodium edta also acts as a food additive.
Disodium edta has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten.
Disodium edta has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.
Chelator of divalent cations.
Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Pharmaceutical Applications
Disodium edta is used as a chelating agent in a wide range of pharmaceutical preparations, including mouthwashes, ophthalmic preparations, and topical preparations, typically at concentrations between 0.005 and 0.1% w/v.
Disodium edta forms stable water-soluble complexes (chelates) with alkaline earth and heavy-metal ions.
The chelated form has few of the properties of the free ion, and for this reason chelating agents are often described as ‘removing’ ions from solution, a process known as sequestering.
The stability of the metal–edetate complex is dependent on the metal ion involved and the pH.
Disodium edta is also used as a water softener as it will chelate calcium and magnesium ions present in hard water.
Disodium edta is also used therapeutically as an anticoagulant as it will chelate calcium and prevent the coagulation of blood in vitro.
Concentrations of 0.1% w/v are used in small volumes for hematological testing and 0.3% w/v in transfusions.

Production Methods
Disodium edta may be prepared by the reaction of edetic acid and sodium hydroxide.

Manufacturing Process
10 mols of ethylene diamine as a 30% aqueous solution and 4 mols of solid caustic soda are placed in a steam heated kettle supplied with an agitator.
8 mols of sodium cyanide as a concentrated water solution (about 30%) are added and the solution heated to 60°C.
About a 10 inch vacuum is applied to bring the liquid to incipient boiling.
Formaldehyde (7.5 mols of 37% to 40% aqueous solution) is slowly added, the temperature being held at 60°C, and the solution vigorously stirred.
Then, when the evolution of ammonia has substantially stopped, an additional 8 mols of sodium cyanide, followed by 8 mols of formaldehyde are added as before.

This is continued until 40 mols of cyanide and 40 mols of formaldehyde have been added.
Then at the end about 2 mols more of formaldehyde are added, making 42 mols in all, to remove any last traces of cyanide.
About 8 to 10 hours are required to complete the reaction.
The resulting product, referred to herein as the crude reaction product, is essentially an aqueous solution of the sodium salt of ethylene diamine tetracetic acid.
To 1,000 g of the crude reaction product are added 264 g of ethylene diamine tetracetic acid.
The mixture is preferably heated to incipient boiling to increase the rate of reaction, and then the mixture is allowed to cool and crystallize.

The crystals formed are filtered off, washed with the smallest possible amount of ice water, and dried to a constant weight, which is 452 g.
A representative sample of the product so prepared showed, upon analysis, 13.26% sodium against a theoretical of 13.70% for the disodium salt.
The dialkali salt has a pH of about 5.3 and behaves like a weak acid, displacing CO2 from carbonates and reacting with metals to form hydrogen.
Disodium edta is a white crystalline solid.

Biochem/physiol Actions
Disodium edta has the ability to block the binding of vasoactive intestinal peptide to macrophage membranes.
Disodium edta is mainly used in the purification of protein, to remove divalent cations and also to prevent protease activity.

Synonyms
Edetate disodium
EDTA disodium salt
139-33-3
Disodium edetate
Edta disodium
Sodium versenate
Titriplex III
Disodium EDTA
Chelest B
Komplexon III
Clewat N
Disodium edathamil
Disodium edta, anhydrous
Zonon D
Edetate disodium anhydrous
Dotite 2NA
Selekton B 2
Tetracemate disodium
Cheladrate
Endrate
Mavacid ED 4
Versonol 120
Chelest 200
Disodium versene
Endrate disodium
Disodium salt of EDTA
Metaquest B
Kiresuto B
Veresene disodium salt
Chelaplex III
Diso-Tate
Chelaton III
Versene NA
Triplex III
Chelaton 3
Disodium versenate
Edathamil disodium
Trilon BD
Versene Na2
Disodium edetate dihydrate
Ethylenediaminetetraacetic acid disodium salt
edta, disodium
Disodium sequestrene
Disodium tetracemate
Disodium ethylenediaminetetraacetate
Sequestrene sodium 2
Ethylenediaminetetraacetic acid, disodium salt
Disotate
Disodium EDTA dihydrate
Perma Kleer Di Crystals
CCRIS 3658
E.D.T.A. disodique [French]
Edetic acid disodium salt
F 1 (VAN)
NSC 2760
Anhydrous disodium edetate
EINECS 205-358-3
Disodium ethylenediamine-N,N,N',N'-tetraacetate
Edetate disodium, anhydrous
Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt
Edetic Acid, Disodium Salt
Edta disodium salt anhydrous
8NLQ36F6MM
Disodium dihydrate edta
E.D.T.A. disodique
Dinatrium ethylendiamintetraacetat [Czech]
EDTA-Na2
EDTA disodium dihydrate
AI3-18049
Edetate Disodium [USAN:BAN]
Disodium dihydrogen ethylenediaminetetraacetate
Ethylenebis(iminodiacetic acid) disodium salt
CHEBI:64734
Perma kleer 50 crystals disodium salt
UNII-8NLQ36F6MM
Disodium ethylenediaminetetraacetic acid
Ethylene diamine tetraacetic acid, disodium salt
Disodium (ethylenedinitrilo)tetraacetate
(Ethylenedinitrilo)-tetraacetic acid disodium salt
UNII-7FLD91C86K
CBC 50152966
DR-16133
Ethylenediaminetetraacetate, disodium salt
Disodium diacid ethylenediaminetetraacetate
Ethylenediaminetetraacetic acid disoium salt dihydrate
MFCD00070672
Disodium (ethylenedinitrilo)tetraacetic acid
EDTA disodium salt (anhydrous)
Chelest f-na
Dinatrium ethylendiamintetraacetat
HSDB 8013
N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine) disodium salt
Disodium dihydrogen(ethylenedinitrilo)tetraacetate
Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt
NSC-2760
Endrate (TN)
NSC-759604
6381-92-6
Na2-EDTA
Disodium edetate hydrate
Ins no.386
Edetate disodium dihydrate
Disodium N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine)
EC 205-358-3
Ins-386
Disodium (ethylenedinitrilo)tetraacetate dihydrate
Edetate Disodium (anhydrous)
F 1
EDETATE DISODIUM (II)
7FLD91C86K
C10H16N2O8.2Na
disodium 2-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate
Disodium dihydrogen ethylenediaminetetraacetate dihydrate
CHEBI:64758
EDETATE DISODIUM (USP-RS)
ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT
C10H14N2Na2O8.2H2O
C10-H16-N2-O8.2Na
ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT, DIHYDRATE
DISODIUM EDETATE (EP IMPURITY)
DISODIUM EDETATE (EP MONOGRAPH)
EDETATE DISODIUM ANHYDROUS (II)
NSC 759604
EDETATE DISODIUM (USP MONOGRAPH)
C10-H14-N2-O8.2Na.2H2-O
E-386
ethylenediamine tetraacetic acid disodium salt
disodium 2-((2-((carboxylatomethyl)(carboxymethyl)amino)ethyl)(carboxymethyl)amino)acetate
Ethylenediaminetetraacetic acid, disodium salt, dihydrate
(ETHYLENEDINITRILO) TETRAACETIC ACID DISODIUM SALT DIHYDRATE
Na2EDTA
Glicina, N,N'-1,2-Etanodiilbis [N-(carboximetil)-, sal de sodio (1:2)
0.5M Sodium EDTA
Disodium edetate (TN)
Na2.EDTA
Glicina, n,n'-1,2-etanodiilbis[n-(carboximetil)-, sal de sodio, hidrato (1:2:2)
GLYCINE, N,N'-1,2-ETHANEDIYLBIS N-(CARBOXYMETHYL)-, DISODIUM SALT, DIHYDRATE
Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt, dihydrate
Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt, dihydrate
CHEMBL1749
DTXSID9027073
ZGTMUACCHSMWAC-UHFFFAOYSA-L
disodium ethylenediamine-tetraacetate
C10H14N2O8.2H2O.2Na
Edetic Acid, Disodium Salt, Dihydrate
DB14600
LS-2377
SB40706
E386
LS-54439
ethylenediaminetetracetic acid disodium salt
EN300-35828
ethylenediaminetetra-acetic acid disodium salt
D03945
P17519
J-007267
J-521348
Q4532977
disodium 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate
Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, sodium salt (1:2)
(Ethylenedinitrilo)tetraacetic acid disodium salt, EDTA disodium salt, EDTA-Na2
disodium;2-[2-[carboxylatomethyl(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate
DISODIUM 2-({2-[(CARBOXYLATOMETHYL)(CARBOXYMETHYL)AMINO]ETHYL(CARBOXYMETHYL)AMINO)ACETATE
DISODIUM EDTA
DESCRIPTION:

EDTA (ethylenediaminetetraacetic acid) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in a product.
Disodium EDTA is in many products as a preservative, to stabilise Disodium EDTA, or to enhance the foaming action.
Disodium EDTA is also used as a chelating agent, which means Disodium EDTA us used to precipitate out metals from the formulation (if tap water were used to make the formulation instead purified water, for example, and Disodium EDTA can bind with metals dissolved in your shower water).

CAS number 6381-92-6
European Community (EC) Number: 205-358-3
Form White crystalline solid
Hill Formula C₁₀H₁₄N₂Na₂O₈ • 2H₂O
Chemical formula C₁₀H₁₄N₂Na₂O₈ • 2H₂O


EDTA is insignificantly absorbed through the skin, hardly metabolised and rapidly eliminated.
The safety margin for the use of EDTA in cosmetics is thus 300,000 times higher than the required minimum safety margin.

EDTA and its salts are irritating at high concentration levels, but they are only used at very low concentrations (< 0.5 %) in cosmetic products.
These concentrations are clearly below the irritation threshold.
Furthermore, the skin and eye compatibility of cosmetic products is being evaluated before it is placed on the market.

EDTA is not considered a persistent, bioaccumulative or toxic pollutant.
However, it is poorly biodegradable.
The European Commission considers that the risk linked to heavy metals only exists under particular circumstances, due to the trapping of EDTA/heavy metal complexes in sediments.

A salt of an organic acid (Ethylenediaminetetraacetic Acid, disodium salt) used in aqueous solutions with other reagents and inert materials for the preparation of cleaning mixtures and poultices to be applied to stone surfaces and frescoes.
EDTA disodium salt, for its property of complexing calcium within crusts and for its good solubility (better than tetrasodium salt), is used in the AB 57 poultice (I.C.R. formulation - Rome).
Disodium EDTA is besides a strong chelating agent of a great many metallic cations, as iron and copper; this property can be utilized to remove stains of rust or copper green from stone surfaces, wood, plasters, etc.

EDTA, Disodium Salt, Dihydrate is an extensively used chelator of divalent cations such as Ca2+.
EDTA (Ethylenediaminetetraacetic acid) is a chelating agent, a general chemical, and a sequestrant.
In molecular biology applications, Disodium EDTA is used to minimize metal ion contaminants.

Also, Disodium EDTA can facilitate enzymatic reactions that could be inhibited by heavy metal traces.
On the other hand, Disodium EDTA can inhibit enzymes, such as metalloproteases, that require divalent cations for activity.

EDTA disodium salt Na2H2 - 2H2O (dihydrate).
EDTA disodium salt is mainly used for its ability to bind to metal ions precipitating lead and other metals in solution, often used as a chelating agent in aquaria.
Together with iron sulphate heptahydrateis used to increase the amount of iron in aquariums.


USES OF DISODIUM EDTA:
Disodium EDTA (chemical formula - C10H16N2Na2O8) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in a product.
This white, water-soluble solid is widely used to bind to metal ions like iron and calcium ions and prevent the deterioration of cosmetics and personal care products.
Disodium EDTA thus enhances stability of cosmetics.

Disodium EDTA is widely used and can be found in moisturizers, skincare and cleansing products, personal cleanliness products, bath soaps, shampoos and conditioners, hair dyes, hair bleaches, and many other product types.
Disodium EDTA and the related ingredients bind to metal ions which inactivates them.
The binding of metal ions helps prevent the deterioration of cosmetics and personal care products thus enhancing their stability.

Disodium EDTA also helps to maintain clarity, protect fragrance compounds, and prevent rancidity.
Disodium EDTA is used up to 0.85% concentration in leave-on products.
For both skin care and hair care applications, Disodium EDTA prevents metal ions from depositing on the surface.

FUNCTION(S) OF DISODIUM EDTA IN COSMETIC PRODUCTS:
CHELATING:
Binds metal ions which could negatively affect the stability and / or appearance of cosmetics
VISCOSITY CONTROLLING:
Increases or decreases the viscosity of cosmetic products
Origin: synthetic
Disodium EDTA is mainly synthesized from ethylenediamine (1,2-diaminoethane), formaldehyde, and sodium cyanide.
This route yields the tetrasodium EDTA, which is converted in a subsequent step into the acid forms.
Occurrence in cosmetics: Various cosmetics
Occurrence in other products:
Medicinal products and medical devices (such as injection solutions, ointments, tinctures, eye or nose drops), foodstuffs


APPLICATIONS OF DISODIUM EDTA:
Substance manufacture.
Intermediates formulation
Powder formulation, liquid
Adhesives, sealants
Biocidal product
Coatings and paints
Solvents
Paint strippers
Metal surface treatment products, including electroplating and electrolysis products
Photochemical additive
Textile dyes, finishing and impregnating products
Cleaning and washing products






SAFETY INFORMATION ABOUT DISODIUM EDTA:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product



CHEMICAL AND PHYSICAL PROPERTIES OF DISODIUM EDTA:

Molecular Weight: 315.23 g/mol
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 10
Rotatable Bond Count 11
Exact Mass 315.08043475 g/mol
Monoisotopic Mass 315.08043475 g/mol
Topological Polar Surface Area 156Ų
Heavy Atom Count 21
Formal Charge 1
Complexity 316
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized: Yes
Physical state: Crystals
Colour: White
Odour: Odourless
pH: 4-6 1% current USP
Melting point/Melting range: 252ºC measured Decomposes
Flammability (solid/gas): No, not expected to form explosive dust/air mixtures.
Vapour pressure: Solubility in water: 10% at 25ºC
Kinematic viscosity: Solid
Explosive properties: Non-explosive
Oxidising properties: No
SPECIFICATIONS OF DISODIUM EDTA:
Purity: min.99.0%
Insolubles: <0.005%
pH(5%,Water)@25°C: 4.0-6.0
Heavy metals(as Pb): <0.005%
Iron: <0.01%
Nitrilotriacetic Acid: <0.1%
RNase, DNase Activity: none detected

Maximum limit of impurities:
Appearance of solution: passes test
Insoluble matter in H2O: 0.01 %
Loss on drying at 150°C 6h: 8.7-11.4 %
Chloride (Cl): 0.02%
Sulfate (SO4): 0.1%
Residual solvents (Ph.Eur/USP): passes test
Nitrilotriacetic Acid [(CH2COOH)3N]: 0.1%
Ca: passes test
Fe: 0.0005 %
STORAGE AND SHIPPING INFORMATION OF DISODIUM EDTA:
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special Instructions Following reconstitution, store at room temperature (20°C). Stock solutions are stable for up to 6 months at 20°C.



SYNONYMS OF DISODIUM EDTA:
Acid, Edetic
Acid, Ethylenediaminetetraacetic
Acid, Ethylenedinitrilotetraacetic
Calcitetracemate, Disodium
Calcium Disodium Edetate
Calcium Disodium Versenate
Calcium Tetacine
Chelaton 3
Chromium EDTA
Copper EDTA
Coprin
Dicobalt EDTA
Dinitrilotetraacetate, Disodium Ethylene
Dinitrilotetraacetate, Ethylene
Disodium Calcitetracemate
Disodium EDTA
Disodium Ethylene Dinitrilotetraacetate
Disodium Versenate, Calcium
Distannous EDTA
Edathamil
Edetate Disodium Calcium
Edetate, Calcium Disodium
Edetates
Edetic Acid
Edetic Acid, Calcium Salt
Edetic Acid, Calcium, Sodium Salt
Edetic Acid, Chromium Salt
Edetic Acid, Dipotassium Salt
Edetic Acid, Disodium Salt
Edetic Acid, Disodium Salt, Dihydrate
Edetic Acid, Disodium, Magnesium Salt
Edetic Acid, Disodium, Monopotassium Salt
Edetic Acid, Magnesium Salt
Edetic Acid, Monopotassium Salt
Edetic Acid, Monosodium Salt
Edetic Acid, Potassium Salt
Edetic Acid, Sodium Salt
EDTA
EDTA, Chromium
EDTA, Copper
EDTA, Dicobalt
EDTA, Disodium
EDTA, Distannous
EDTA, Gallium
EDTA, Magnesium Disodium
EDTA, Potassium
EDTA, Stannous
Ethylene Dinitrilotetraacetate
Ethylene Dinitrilotetraacetate, Disodium
Ethylenediaminetetraacetic Acid
Ethylenedinitrilotetraacetic Acid
Gallium EDTA
Magnesium Disodium EDTA
N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine)
Potassium EDTA
Stannous EDTA
Tetacine, Calcium
Tetracemate
Versenate
Versenate, Calcium Disodium
Versene
Cheladrate
Endrate
Edta disodium
Disodium edetate
Disodium versene
Edetate disodium
Endrate disodium
Sodium versenate
Metaquest B
Kiresuto B
Chelaplex III
Diso-Tate
Titriplex III
Chelaton III
Versene NA
Chelaton 3
Disodium EDTA
Triplex III
Disodium versenate
Edathamil disodium
Trilon BD
Versene Na2
Disodium sequestrene
Disodium tetracemate
EDTA disodium salt
Sequestrene sodium 2
Disodium salt of EDTA
Perma Kleer Di Crystals
Edetic acid disodium salt
Versenate
Sequestrene Na2
Trilon B
Selekton B2
Disodium ethylenediaminetetraacetate
Perma kleer 50 crystals disodium salt
Disodium (ethylenedinitrilo)tetraacetate
Disodium ethylenediaminetetraacetic acid
SODIUM ETHYLENEDIAMINETETRAACETATE
CBC 50152966
DR-16133
Ethylenediaminetetraacetate, disodium salt
Disodium diacid ethylenediaminetetraacetate
D'E.d.t.a. disodique
Disodium (ethylenedinitrilo)tetraacetic acid
Ethylenediaminetetraacetic acid disodium salt
Disodium dihydrogen ethylenediaminetetraacetate
Ethylenediaminetetraacetic acid, disodium salt
Disodium dihydrogen(ethylenedinitrilo)tetraacetate
139-33-3
NSC2760
NSC-2760
NSC-759604
6381-92-6
7379-28-4
(Ethylenedinitrilo)tetraacetic acid, disodium salt
Pharmakon1600-01300016
Pharmakon1600-01500270
NSC756746
NSC759604
WLN: QV1N1VQ2N1VQ1VQ &-NA-2
Disodium dihydrogen ethylenediaminetetracetate
Disodium ethylenediamine-N,N',N'-tetraacetate
A886053
(ETHYLENEDINITRILO)TETRAACETIC ACID, DIHYDRATE
Glycine,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt
Glycine, N,N inverted exclamation marka-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt (1:?)
EDTA disodium salt
(Ethylenedinitrilo)tetraacetic acid disodium salt
139-33-3 [RN]
2,2',2'',2'''-(1,2-Éthanediyldinitrilo)tetraacétate de hydrogène et de sodium (1:2:2) [French] [ACD/IUPAC Name]
2,2'-{1,2-Éthanediylbis[(carboxyméthyl)imino]}diacétate de disodium [French] [ACD/IUPAC Name]
2,2'-{éthane-1,2-diylbis[(carboxyméthyl)imino]}diacétate de disodium [French]
Acetate, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, hydrogen sodium salt (1:2:2) [ACD/Index Name]
Acetic acid, (ethylenedinitrilo)tetra-, disodium salt
Chelaplex III [Trade name]
Dinatrium-2,2'-{1,2-ethandiylbis[(carboxymethyl)imino]}diacetat [German] [ACD/IUPAC Name]
Dinatrium-2,2'-{ethan-1,2-diylbis[(carboxymethyl)imino]}diacetat [German]
Disodium 2,2'-{1,2-ethanediylbis[(carboxymethyl)imino]}diacetate [ACD/IUPAC Name]
disodium 2,2'-{ethane-1,2-diylbis[(carboxymethyl)imino]}diacetate
DISODIUM EDTA
Edetate disodium [BAN] [USAN] [USP]
Edetate disodium anhydrous
Edetic acid disodium salt
EDTA disodium
EDTA-Na2
Endrate disodium
ethylenediaminetetraacetic acid disodium
Ethylenediaminetetraacetic acid, disodium salt
MFCD00070672 [MDL number]
Natriumhydrogen-2,2',2'',2'''-(1,2-ethandiyldinitrilo)tetraacetat (2:2:1) [German] [ACD/IUPAC Name]
Sodium hydrogen 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetraacetate (2:2:1) [ACD/IUPAC Name]
Sodium N,N'-ethane-1,2-diylbis(N-(carboxymethyl)glycinate)
Tetracemate disodium
Titriplex III [Trade name]
Triplex III [Trade name]
Versene Disodium Salt
(Ethylenedinitrilo)-tetraacetic acid disodium salt
205-358-3 [EINECS]
Cheladrate
Chelaton 3
Chelaton III
Chelest 200
Chelest B
Clewat N
Collyrium Fresh-Eye Drops
Dinatrium ethylendiamintetraacetat [Czech]
Disodium (ethylenedinitrilo)tetraacetate
Disodium (ethylenedinitrilo)tetraacetic acid
DISODIUM 2-({2-[(CARBOXYLATOMETHYL)(CARBOXYMETHYL)AMINO]ETHYL}(CARBOXYMETHYL)AMINO)ACETATE
DISODIUM 2-({2-[BIS(CARBOXYMETHYL)AMINO]ETHYL}(CARBOXYLATOMETHYL)AMINO)ACETATE
disodium 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate
disodium 2,2',2'',2'''-(ethane-1,2-diyldiammonio)tetraacetate
disodium 2-[2-[bis(carboxymethyl)amino]ethyl-(2-oxido-2-oxo-ethyl)amino]acetate
Disodium diacid ethylenediaminetetraacetate
Disodium dihydrogen (ethylenedinitrilo)tetraacetate
Disodium dihydrogen ethylenediaminetetraacetate
disodium dihydrogen ethylenediaminetetraacetic acid
Disodium dihydrogen(ethylenedinitrilo)tetraacetate
Disodium edathamil
DISODIUM EDETATE
Disodium Edetate, Disodium EDTA, Ethylenedinitriletetraacetic Acid Disodium salt, N,N'-1,2-Ethanediyl-bis[N-(Carboxymethyl)Glycine
Disodium ethylenediamine-N,N,N',N'-tetraacetate
disodium ethylene-diamine-tetra-acetate
DISODIUM ETHYLENEDIAMINETETRAACETATE
Disodium N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine)
DISODIUM SEQUESTRENE
Disodium tetracemate
Disodium versenate
Disodium versene
Disotate
Diso-Tate
Dotite 2NA
E.D.T.A. disodique [French]
Edathamil disodium
Edetate Disodium (anhydrous)
Edetate Sodium [USAN]
Endrate [Trade name]
Ethylene diamine tetraacetic acid, disodium salt
Ethylenebis(iminodiacetic acid) disodium salt
ethylenebis(iminodiacetic acid) disoidum salt
ethylenediaminetetraacetate disodium
Ethylenediaminetetraacetate, disodium salt
Ethylenediaminetetraacetic acid disodium salt
Ethylenedinitrilotetraacetic acid disodium salt
Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt
IDRANAL® 100
Kiresuto B
Komplexon III
Mavacid ED 4
Metaquest B
MFCD00012470 [MDL number]
MFCD00150037 [MDL number]
N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine) disodium salt
N,N'-1,2-Ethanediylbis[N-(carboxymethyl)glycine] Disodium Salt
N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], disodium salt
Na2-EDTA
Na2H2EDTA
Selekton B 2
Selekton B2
Sequestrene sodium 2
Sodium 2,2'-((2-(bis(carboxymethyl)amino)ethyl)azanediyl)diacetate
Sodium edetate
Sodium versenate [Trade name]
Titriplex(R) IIImissing
Trilon B
Trilon BD
Veresene disodium salt
Versene NA
Versene Na2
Versonol 120
Zonon D



DISODIUM EDTA-COPPER
DISODIUM ETIDRONATE. N° CAS : 7414-83-7. Nom INCI : DISODIUM ETIDRONATE. Nom chimique : Disodium dihydrogen (1-hydroxyethylidene)bisphosphonate.N° EINECS/ELINCS : 231-025-7 Ses fonctions (INCI): Agent de chélation : Réagit et forme des complexes avec des ions métalliques qui pourraient affecter la stabilité et / ou l'apparence des produits cosmétiques. Noms français : (1-HYDROXYETHYLIDENE)DIPHOSPHONIC ACID, DISODIUM SALT 1-HYDROXYETHANE-1,1-DIPHOSPHONIC ACID DISODIUM SALT DISODIUM (1-HYDROXYETHYLIDENE)-1,1-BIPHOSPHONATE DISODIUM 1-HYDROXY-1,1-ETHANEDIPHOSPHONATE DISODIUM 1-HYDROXYETHANE-1-DIPHOSPHONATE DISODIUM 1-HYDROXYETHANEDIPHOSPHONATE DISODIUM 1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONATE DISODIUM 1-HYDROXYETHYLIDENEDIPHOSPHONATE DISODIUM DIHYDROGEN (1-HYDROXYETHYLIDENE)DIPHOSPHATE DISODIUM ETHAN0L-1,1-DIPHOSPHONATE DISODIUM ETHANE-1-HYDROXY-1,1-DIPHOSPHONATE DISODIUM ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID DISODIUM ETHANE-1-HYDROXY-1-DIPHOSPHONATE DISODIUM ETHYDRONATE DISODIUM ETIDRONATE ETHANE-1-HYDROXY-1,1-DIPHOSPHONATE DISODIUM ETHANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID, DISODIUM SALT ETHYDRONATE DE SODIUM ETIDRONATE DE SODIUM ETIDRONATE DISODIQUE PHOSPHONIC ACID, (1-HYDROXYETHYLIDENE)BIS-, DISODIUM SALT PHOSPHONIC ACID, (HYDROXYETHYLIDENE)DI-, DISODIUM SALT SEL DISODIQUE DE L'ACIDE HYDROXYETHANE-1 DIPHOSPHONIQUE-1,1 SODIUM ETHANE-1-HYDROXY-1,1-DIPHOSPHONATE Utilisation et sources d'émission; Médicament
DISODIUM ETIDRONATE
DIBASIC SODIUM PHOSPHATE; DIBASIC SODIUM PHOSPHATE HEPTAHYDRATE; DISODIUM HYDROGEN PHOSPHATE; DI-SODIUM HYDROGEN PHOSPHATE-7-HYDRATE; DISODIUM HYDROGEN PHOSPHATE HEPTAHYDRATE; DISODIUM PHOSPHATE; DISODIUM PHOSPHATE HEPTAHYDRATE; DSP; DSP HEPTAHYDRATE; MONOHYDROGEN SODIUM PHOSPHATE; SECONDARY SODIUM PHOSPHATE; SECONDARY SODIUM PHOSPHATE HEPTAHYDRATE; SEC-SODIUM PHOSPHATE HEPTAHYDRATE; SODIUM HYDROGEN PHOSPHATE; SODIUM HYDROGEN PHOSPHATE HEPTAHYDRATE; SODIUM MONOHYDROGEN PHOSPHATE HEPTAHYDRATE; SODIUM PHOSPHATE 7H2O, DIBASIC; SODIUM PHOSPHATE DIBASIC; SODIUM PHOSPHATE, DIBASIC, 7-HYDRATE; SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE CAS NO:7782-85-6
DISODIUM HYDROGEN PHOSPHATE HEPTAHYDRATE
DISODIUM HYDROXYETHYLIMINODIACETATE. N° CAS : 135-37-5. Nom INCI : DISODIUM HYDROXYETHYLIMINODIACETATE. Nom chimique : Disodium 2-hydroxyethyliminodi(acetate) N° EINECS/ELINCS : 205-187-4. Classification : Composé éthoxylé. Ses fonctions (INCI).Agent de chélation : Réagit et forme des complexes avec des ions métalliques qui pourraient affecter la stabilité et / ou l'apparence des produits cosmétiques
DISODIUM HYDROGEN PHOSPHATE HEPTAHYDRATE
Disodium hydrogen phosphate heptahydrate is the inorganic compound with the formula Na2HPO4.
Disodium hydrogen phosphate heptahydrate is one of several sodium phosphates.
Disodium hydrogen phosphate heptahydrate is known in anhydrous form as well as forms with 2, 7, 8, and 12 hydrates.

CAS: 7782-85-6
MF: H6NaO5P
MW: 140.01
EINECS: 616-512-8

All are water-soluble white powders; the anhydrous salt being hygroscopic.
Disodium hydrogen phosphate heptahydrate is a reagent with very high buffering capacity widely used in molecular biology, biochemistry and chromatography.
Disodium hydrogen phosphate heptahydrate is highly hygroscopic and water soluble.

Disodium hydrogen phosphate heptahydrate Chemical Properties
Melting point: 48 °C
Density: 1.68 g/mL at 25 °C(lit.)
Vapor density: 4.9 (vs air)
Storage temp.: Store at +5°C to +30°C.
Solubility: 154g/l
Form: Solid
Color: White
Specific Gravity: 1.7
PH Range: 8.7 - 9.3
PH: 8.7-9.3 (25℃, 5% in solution)
Water Solubility: Soluble in water and insoluble in ethanol.
Merck: 14,8659
LogP: -2.148 (est)
CAS DataBase Reference: 7782-85-6(CAS DataBase Reference)
EPA Substance Registry System: Disodium hydrogen phosphate heptahydrate (7782-85-6)

The USP 32 states that Disodium hydrogen phosphate heptahydrate is dried or contains, 1, 2, 7, or 12 molecules of water of hydration.
Anhydrous Disodium hydrogen phosphate heptahydrate occurs as a white powder.
The dihydrate occurs as white or almost white, odorless crystals.
The heptahydrate occurs as colorless crystals or as a white granular or caked salt that effloresces in warm, dry air.
The dodecahydrate occurs as strongly efflorescent, colorless or transparent crystals.

Uses
Disodium hydrogen phosphate heptahydrate is used as precursor in the preparation of cobalt-based molecular catalyst for water oxidation.
Disodium hydrogen phosphate heptahydrate has been used to prepare sodium phosphate buffer and phosphate-buffered saline (PBS) buffer.

Disodium hydrogen phosphate heptahydrate is widely used in detergents and cleaning agents.
Combined with trisodium phosphate, Disodium hydrogen phosphate heptahydrate is employed in the food industry to adjust the pH and in water treatment to prevent calcium scale formation.
Disodium hydrogen phosphate heptahydrate is utilized as a saline laxative to clean the bowel before a colonoscopy.
Disodium hydrogen phosphate heptahydrate prevents the coagulation of condensed milk.
Disodium hydrogen phosphate heptahydrate is also utilized as anti-caking additive in powdered products.
Disodium hydrogen phosphate heptahydrate enhances the cook time and used as thickening agent in desserts and puddings.

Disodium hydrogen phosphate heptahydrate is used in conjunction with trisodium phosphate in foods and water softening treatment.
In foods, Disodium hydrogen phosphate heptahydrate is used to adjust pH.
Disodium hydrogen phosphate heptahydrate's presence prevents coagulation in the preparation of condensed milk.
Similarly, Disodium hydrogen phosphate heptahydrate is used as an anti-caking additive in powdered products.
Disodium hydrogen phosphate heptahydrate is used in desserts and puddings, e.g. Cream of Wheat to quicken cook time, and Jell-O Instant Pudding for thickening.
In water treatment, Disodium hydrogen phosphate heptahydrate retards calcium scale formation.
Disodium hydrogen phosphate heptahydrate is also found in some detergents and cleaning agents.

Heating solid Disodium hydrogen phosphate heptahydrate gives the useful compound tetrasodium pyrophosphate:

2 Na2HPO4 → Na4P2O7 + H2O

Pharmaceutical Applications
Disodium hydrogen phosphate heptahydrate is used in a wide variety of pharmaceutical formulations as a buffering agent and as a sequestering agent.
Therapeutically, Disodium hydrogen phosphate heptahydrate is used as a mild laxative and in the treatment of hypophosphatemia.
Disodium hydrogen phosphate heptahydrate is also used in food products; for example as an emulsifier in processed cheese.

Production Methods
Either bone phosphate (bone ash), obtained by heating bones to whiteness, or the mineral phosphorite is used as a source of tribasic calcium phosphate, which is the starting material in the industrial production of dibasic sodium phosphate.
Tribasic calcium phosphate is finely ground and digested with sulfuric acid.
This mixture is then leached with hot water and neutralized with sodium carbonate, and Disodium hydrogen phosphate heptahydrate is crystallized from the filtrate.

Production and reactions
Disodium hydrogen phosphate heptahydrate can be generated by neutralization of phosphoric acid with sodium hydroxide:

H3PO4 + 2 NaOH → Na2HPO4 + 2 H2O
Industrially Disodium hydrogen phosphate heptahydrate is prepared in a two-step process by treating dicalcium phosphate with sodium bisulfate, which precipitates calcium sulfate:

CaHPO4 + NaHSO4 → NaH2PO4 + CaSO4
In the second step, the resulting solution of monosodium phosphate is partially neutralized:

NaH2PO4 + NaOH → Na2HPO4 + H2O

Synonyms
7782-85-6
Sodium phosphate dibasic heptahydrate
Sodium phosphate, dibasic, heptahydrate
Disodium phosphate heptahydrate
disodium;hydrogen phosphate;heptahydrate
UNII-70WT22SF4B
70WT22SF4B
Phosphoric acid, disodium salt, heptahydrate
Sodium hydrogen phosphate heptahydrate
Sodium phosphate, diabasic, heptahydrate
MFCD00149180
disodium hydrogenphosphate heptahydrate
HO4P.2Na.7H2O
Sodiumphosphatedibasicheptahydrate
H-O4-P.2Na.7H2-O
DTXSID10872533
heptahydratedibasicsodium phosphate
NATRUM PHOSPHORICUM [HPUS]
sodium hydrogenphosphate heptahydrate
DIBASIC SODIUM PHOSPHATE HEPTAHYDRATE
FT-0625319
SODIUM PHOSPHATE DIBASIC (HEPTAHYDRATE)
Sodium phosphate dibasic heptahydrate ACS grade
Sodium phosphate dibasic heptahydrate USP grade
Sodium monohydrogen phosphate heptahydrate (2:1:7)
SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE [II]
SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE [MI]
SODIUM PHOSPHATE,DIBASIC,HEPTAHYDRATE [VANDF]
Q27265904
SODIUM PHOSPHATE DIBASIC (HEPTAHYDRATE) [WHO-DD]
Sodium phosphate dibasic heptahydrate, Trace metals grade
SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE [ORANGE BOOK]
DISODIUM HYDROXYETHYLIMINODIACETATE
disodium laureth sulfosuccinate; Dioctyl sulfosuccinate sodium salt; AOT; Bis(2-ethylhexyl) sulfosuccinate sodium salt; DOSS; Docusate sodium; Poly(Oxy-1,2-Ethanediyl), .alpha.-(3-Carboxy-1-Oxo-3-Sulfopropyl)-.omega.-(Dodecyloxy)-, Disodium Salt CAS Number: 39354-45-5 / 40754-59-4 / 42016-08-0 / 58450-52-5 / 68815-56-5
DISODIUM INOSINATE
Disodium inosinate is a colorless to white crystal or crystalline powder with a characteristic taste.
Disodium inosinate (E631) is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P.
Disodium inosinate is also soluble in organic solvents like ethanol and insoluble in ether.

CAS Number: 4691-65-0
Molecular Formula: C10H14N4NaO8P
Molecular Weight: 372.21
EINECS Number: 225-146-4

Disodium inosinate contains approximately 7.5 molecules of water of crystallization.
Disodium inosinate is odorless and has characteristic taste.
For other details of description, see Disodium inosinate.

Disodium inosinate is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks.
Commercial disodium inosinate may either be obtained from bacterial fermentation of sugars or prepared from animal products.
The Vegetarian Society reports that production from meat or fish is more widespread, but the Vegetarian Resource Group reports that all three "leading manufacturers" claim to use fermentation.

Disodium inosinate is provided as delivered and specified.
All information provided in support of this product, including SDS and any product nformation leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
Disodium inosinate is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P.

However, the stability of Disodium inosinate is very high as it remains absolutely stable at 100 °C.
Until the temperature is around 230 °C, Disodium Inosinate will not decompose.
Disodium inosinate (E631), chemical formula C10H11N2Na2O8P, is the disodium salt of inosinic acid.

Disodium Inosinate is a food additive often found in instant noodles, potato chips, and a variety of other snacks.
Disodium Inosinate is used as a flavor enhancer, in synergy with monosodium glutamate to provide the umami taste.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Disodium inosinate is the disodium salt of inosinic acid which belongs to the group of purine-5′-nucleotides.
Disodium inosinate is generally used as a taste and flavor enhancer in foods to provide umami taste.
As Disodium Inosinate is a fairly expensive additive, it is not used independently of lutamic acid; if disodium inosinate is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient.

Disodium Inosinate is often added to foods in conjunction with disodium guanylate; the combination is known as disodium Disodium Inosinate.
Disodium Inosinate is a chemical compound that is added to foods as a flavor enhancer, to improve the taste of foods.
Disodium inosinate Flavor Enhancer is soluble in water while slightly soluble in alcohol.

Flavor Enhancer Disodium inosinate is often added to foods in conjunction with E627 Flavour Enhancer and the combination is known as disodium ribonucleotides (I+G).
Disodium inosinate Halal Food Additive is widely used in instant noodles, potato chips and other snacks, savory rice, tinned vegetables, cured meats and packaged soup.
Sinofi is a reliable Disodium Inosinate supplier and manufacturer in China.

Disodium inosinate (IMP), a kind of nucleotide, also known as Disodium inosinate, is a flavor enhancer with the European food additive number E631.
Its purpose in food is to add a meaty or savory flavor, which is called umami taste.
IMP is a white granular or powder commonly combined with another flavour enhancer disodium guanylate (GMP) as disodium 5′-ribonucleotides (E635) or with monosodium glutamate (MSG).

Disodium inosinate is a food additive with the E number E631.
Disodium inosinate is a salt of inosinic acid, a naturally occurring nucleoside found in various foods, especially in meat and fish.
Disodium inosinate is primarily used as a flavor enhancer in the food industry, and it is often used in combination with another flavor enhancer, monosodium glutamate (MSG), represented as E621.

Disodium inosinate is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks.
Although Disodium inosinate can be obtained from bacterial fermentation of sugars, Disodium inosinate is often commercially prepared from animal products.
Disodium inosinate is generally produced from meat, including chicken.

Though Disodium inosinate is normally a non-vegetarian product, Disodium inosinate also may be produced from tapioca starch without any animal products involved in the production.
The producer can provide information on the origin and Disodium inosinate is in some cases labeled as "vegetarian" in ingredients lists when produced from plant sources.
Disodium inosinate is a flavor enhancer with the European food additive number E631.

Disodium inosinates purpose in food is to add a meaty or savory flavor, which is called umami taste.
Disodium Inosinate is a white granular or powder commonly combined with another flavour enhancer disodium guanylate (GMP) as Disodium inosinate or with monosodium glutamate (MSG).
Disodium Inosinate is one of the most used food enhancers that you’ll find in a great variety of grocery products.

Usually, Disodium inosinate’s combined with other flavor enhancers like monosodium glutamate.
Disodium inosinate -E631- is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P.
Disodium inosinate is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks.

Although it can be obtained from bacterial fermentation of sugars, it is often commercially prepared from animal sources.
Disodium inosinate is the disodium salt of inosinic acid, which works as a food enhancer.
The taste Disodium Inosinate in food generates is kind of meaty and savory, which is also known as umami taste.

Usually, foods containing this flavor are irresistibly tasty and addictive.
Flavour enhancer As it is a fairly expensive additive, it usually is not used independently of glutamic acid; if disodium inosinate is present in a list of ingredients but MSG does not appear to be, it is possible that glutamic acid is provided as part of another ingredient or is naturally occurring in another ingredient like tomatoes, Parmesan cheese or yeast extract.
Disodium inosinate is often added to foods in conjunction with disodium guanylate; the combination is known as disodium 5'-ribonucleotides.; Disodium inosinate (E631), chemical formula C10H11N2Na2O8P, is the disodium salt of inosinic acid.

Disodium inosinate is a food additive often found in instant noodles, potato chips, and a variety of other snacks.
Disodium inosinate is used as a flavor enhancer, in synergy with monosodium glutamate (also known as MSG; the sodium salt of glutamic acid) to provide the umami taste.
Disodium inosinate is mainly found in animals like pigs and fish.

Disodium inosinates are some other names of this food flavor.
Disodium inosinate is one of the majorly used food flavors in fast foods, processed foods.
The CAS number of Disodium inosinate is 4691-65-0 and the molecular weight is 392.17(anhydrous).

Disodium Inosinate can be made by two methods.
Disodium inosinate can be produced from bacterial fermentation of sugar or carbon source.
Also, Disodium inosinate can be produced by the degradation of nucleotides into nucleic acid from yeast extract (Learn yeast’s vegan status with this article).

Disodium inosinate is an expensive product and mostly combined with other enhancers like monosodium glutamate (MSG) and disodium guanylate (GMP).
When Disodium inosinate is combined with GMP, Disodium inosinate is named as disodium 5′-ribonucleotides or E635.
If Disodium inosinate is not listed in the label of a product while Disodium Inosinate is listed, it is possible that glutamic acid is combined or it naturally occurs from the food ingredients like tomatoes, parmesan cheese, or yeast extract.

Disodium Inosinate appears as a white granular or powder.
Disodium inosinate is odorless and soluble in water.
Disodium inosinate or IMP (E631) is a flavor enhancer and the disodium salt of inosinic acid.

Disodium inosinate also goes by other names such Disodium inosine-5′-monophosphate, Disodium 5′-inosinate, and 5′-inosinic acid.
Like other flavor enhancers, IMP has no particular taste on its own, but has the ability to enhance existing flavors in food.
Disodium inosinate appears as white or colorless granular powder.

Disodium inosinate is soluble in water, but sparingly soluble in ethanol.
Disodium inosinates pH level is between 7.0 and 8.5. It is highly stable 212°F (100°C) and will not decompose until the temperature reaches 446°F (230°C).
IMP imparts meaty, and savory or umami taste in food products such as instant noodles (seasoning), potato chips, canned soups, condiments, and snacks.

Disodium inosinate is seldomly used alone as a food enhancer. But is often added in synergy with other flavor enhancers such as disodium guanylate (GMP) and monosodium glutamate (MSG).
One reason is that disodium inosinate is a relatively expensive ingredient.

Another is that its flavor enhancing flavor is 50% of than of GMP.
However, the most important reason is how the combination makes foods taste much better than that with MSG and/or GMP alone.

Melting point: 175 °C
FEMA: 3669 | DISODIUM 5-INOSINATE
storage temp.: 2-8°C
form: Crystalline Powder
color: White
Odor: odorless
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -1.02
CAS DataBase Reference: 4691-65-0(CAS DataBase Reference)
FDA 21 CFR: 172.535; 155.120; 155.130; 155.170
Substances Added to Food (formerly EAFUS): DISODIUM INOSINATE
EWG's Food Scores: 1

Disodium inosinate, when used in combination with other flavor enhancers such as monosodium glutamate (MSG) and disodium guanylate (E627), can create a synergistic effect known as the "umami synergy."
This synergy enhances and amplifies the umami taste in foods, making them more savory and appealing.
Disodium inosinate is commonly used in processed and convenience foods, including canned soups, instant noodles, potato chips, savory snacks, frozen meals, and ready-to-eat products.

Disodium inosinate is particularly prevalent in products where intense umami flavor is desired.
In vegetarian and vegan food products that aim to replicate the taste of meat or fish, disodium inosinate is sometimes used to enhance the savory and umami notes, making these plant-based alternatives more appealing to consumers.
The use of disodium inosinate is subject to regulations and safety assessments by food safety authorities in various countries.

Disodium inosinate is essential for food manufacturers to comply with these regulations and adhere to specific usage limits.
Some consumers and food manufacturers are moving toward cleaner label products, which may involve using natural sources of umami flavor rather than synthetic additives like disodium inosinate.
For this reason, some products highlight their use of natural umami sources to cater to consumer preferences.

While disodium inosinate is considered safe for most people, some individuals may experience sensitivity or allergic reactions to food additives.
In response to increasing consumer interest in food additives and ingredient transparency, food manufacturers often provide information about the use of disodium inosinate on product labels.
This allows consumers to make informed choices.

Inosinate is naturally found in meat and fish at levels of 80–800 mg/100 g.
Disodium inosinate can also be made by fermentation of sugars such as tapioca starch.
Some sources claim that industrial levels of production are achieved by extraction from animal products, making E631 non-vegetarian.

However, an interview by the Vegetarian Resource Group reports that all three "leading manufacturers" (one being Ajinomoto) claims to use an all-vegetarian fermentation process.
Producers are generally open to providing information on the origin.
Disodium inosinate is in some cases labeled as "vegetarian" in ingredients lists when produced from plant sources.

Disodium inosinate is often used in combination with monosodium glutamate (MSG) because they have a synergistic effect.
When used together, they enhance and intensify the savory or umami taste of foods more effectively than when used individually.
While disodium inosinate can be synthesized, it can also be derived from natural sources.

Disodium inosinate , the precursor of disodium inosinate, is naturally present in foods like meat, fish, and certain vegetables.
When extracted from natural sources, it is considered a more "clean label" ingredient.
The use of disodium inosinate is regulated by food safety authorities in various countries.

Disodium inosinate is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and has received approval from other regulatory bodies worldwide.
Disodium inosinate is subject to specific usage limits in food products.
Disodium inosinate is valued in the food industry for its ability to enhance the overall flavor of a wide range of processed foods, including soups, broths, snack foods, sauces, and ready-to-eat meals.

Some individuals following vegetarian or vegan diets may want to be cautious about products containing disodium inosinate, as it can sometimes be sourced from animal products.
However, many manufacturers use plant-based sources for disodium inosinate to cater to a broader consumer base.

Transparency and provide consumers with information about food additives, disodium inosinate is required to be listed on ingredient labels.
Disodium inosinate may be listed as "disodium inosinate" or by its E number, E631.

Uses:
Disodium inosinate is used as a flavor enhancer, in synergy with monosodium glutamate (MSG) to provide the umami taste.
Disodium inosinate is often added to foods in conjunction with disodium guanylate; the combination is known as disodium 5′-ribonucleotides.
As a relatively expensive product, disodium inosinate is usually not used independently of glutamic acid; if disodium inosinate is present in a list of ingredients, but MSG does not appear to be, it is possible that glutamic acid is provided as part of another ingredient or is naturally occurring in another ingredient like tomatoes, Parmesan cheese, or yeast extract.

Disodium inosinate is used as a flavor enhancer, in synergy with monosodium glutamate (MSG) to provide the umami taste.
Disodium Inosinate is often added to foods in conjunction with disodium guanylate; the combination is known as disodium 5′-ribonucleotides.
Disodium inosinate can be added to salad dressings and condiments to intensify the umami flavor and improve the taste of these products.

In dips and salsas, disodium inosinate is used to enhance the overall flavor and make them more enjoyable when used as a snack or accompaniment.
Disodium inosinate is sometimes used in Asian cuisine, including sushi and various Japanese dishes, to boost the umami flavor of broths, soy-based sauces, and other components of these dishes.
Disodium inosinate can be used in the production of flavor concentrates and seasonings that are later added to processed foods.

In frozen seafood products, disodium inosinate is used to improve the flavor of items like fish fillets and seafood-based ready meals.
Disodium inosinate is often included in instant gravy mixes to create a more robust and savory gravy with enhanced umami notes.
In addition to instant noodles, disodium inosinate is used in the seasoning packets that accompany various types of noodles.

Some meat marinades and flavor injections for poultry or meat products use disodium inosinate to enhance the savory taste.
Disodium inosinate is sometimes used in flavored rice dishes, like risotto or pilaf, to elevate the umami flavor and improve the overall taste.
Manufacturers of ready-to-use spice blends and rubs may incorporate disodium inosinate to create more flavorful and aromatic products.

Bouillon cubes, which are used for making broths and stocks, can contain disodium inosinate to intensify the taste.
In rare cases, disodium inosinate might be used in savory baked goods, such as bread or crackers, to enhance their flavor.
As a relatively expensive product, disodium inosinate is usually not used independently of glutamic acid; if disodium inosinate is present in a list of ingredients, but MSG does not appear to be, it is possible that glutamic acid is provided as part of another ingredient or is naturally occurring in another ingredient like tomatoes, Parmesan cheese, or yeast extract.

Disodium inosinate is a flavor enhancer that can be used in many processed foods.
Disodium Inosinates flavor enhancing power is around 50% of disodium guanylate.
Commonly used together with MSG or disodium guanylate in seasoning, condiments and salt substitutes for soups, sauces and snack foods but seldom used alone in food.

Disodium inosinate is used as a flavor enhancer, in synergy with monosodium glutamate.
Disodium inosinate is generally produced from meat, including fish and pigs.
Though Disodium Inosinate is normally a non-vegetarian product, it also may be produced from tapioca starch without any animal products involved in the production.

Disodium inosinate may be used as a pharmaceutical reference standard for the determination of the analyte in raw materials and food products by spectrophotometry, and chromatography.
These Secondary Standards are qualified as Certified Reference Materials.
These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Disodium inosinate is commonly used in savory snacks like potato chips, pretzels, and other snack foods to enhance their flavor, making them more appealing to consumers.
Disodium inosinate is a common ingredient in instant noodle products, helping to create a richer and more satisfying broth or sauce.
In processed soups, broths, and bouillons, disodium inosinate is added to amplify the savory and umami taste of the final product.

Many ready-to-eat or microwaveable meals contain disodium inosinate to improve their taste and appeal.
This is especially important in products with meat or savory profiles.
In various sauces and gravies, disodium inosinate is used to enhance the overall flavor, making them more delicious and restaurant-quality.

Disodium inosinate can be included in spice blends and seasonings to intensify the umami aspect of the seasoning and enhance the overall taste of dishes.
Disodium inosinate is used in vegetarian and vegan meat alternatives to create a more convincing savory taste, as it mimics the umami flavor naturally found in animal products.
In canned or processed meat products, Disodium inosinate is used to elevate the umami flavor and improve the overall taste.

Various flavored snack products, such as seasoned popcorn and puffed snacks, may contain disodium inosinate to make the flavor more robust and appealing.
Many frozen foods, including frozen pizzas and entrées, use disodium inosinate to enhance the overall flavor experience.
In general, disodium inosinate is used in a wide range of convenience foods to make them more flavorful and satisfying to consumers.

Toxicology and safety:
Some individuals may have sensitivities or allergies to food additives, including disodium inosinate.
Disodium inosinate is often used in combination with monosodium glutamate (MSG) and disodium guanylate (E627), and this combination can enhance umami flavor.
Some people may experience symptoms such as headaches or "Chinese restaurant syndrome" when consuming foods with these additives, though scientific evidence on this is mixed, and most people do not experience such reactions.

Food manufacturers are required to use disodium inosinate within established safety limits and comply with regulations set by food safety authorities in various countries.
Disodium inosinate is important to ensure that products containing E631 adhere to these regulations.
In the United States, consumption of added 5′-ribonucleotides averages 4 mg per day, compared to 2 g per day of naturally occurring purines.

A review of literature by an FDA committee found no evidence of carcinogenicity, teratogenicity, or adverse effects on reproduction.
In 2004, disodium inosinate was proposed to be removed from the food additive list by Codex Alimentarius Commission.
This change did not go through: it is still present in the 2009 Codex Allimentarius list.

Synonyms:
Disodium 5'-inosinate
4691-65-0
Disodium inosinate
Sodium inosinate
5'-Imp disodium salt
IMP disodium salt
5'-INOSINIC ACID, DISODIUM SALT
FEMA No. 3669
Inosine 5'-monophosphate disodium salt
Disodium inosine-5'-monophosphate
Inosine 5'-monophosphate disodium
Inosine-5'-monophosphate disodium
Sodium 5'-inosinate
5'-IMPdisodium salt
T2ZYA7KC05
5'-Inosinic acid, sodium salt (1:2)
IMP sodium salt
Inosine-5'-monophosphoric acid disodium salt
disodium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl phosphate
Sodium Inosine 5'-Phosphate (2:1)
Disodium inosine 5'-monophosphate
Ribotide
Disodium inosine 5'-phosphate
Inosine 5'-monophosphate, disodium salt
5'-Inosinic Acid Disodium Salt
sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl phosphate
CCRIS 6560
Inosin-5'-monophosphate disodium
EINECS 225-146-4
NSC 20263
Inosic Acid Disodium Salt
UNII-T2ZYA7KC05
5'-IMP 2Na
Disodium 5-Inosinate
Inosine-5'-monophosphate sodium salt
NSC-20263
inosine 5'-monophosphoric acid disodium salt
Inosine monophosphate disodium
SCHEMBL316941
INS NO.631
DISODIUM INOSINATE [FCC]
DTXSID4044242
DISODIUM INOSINATE [INCI]
INS-631
AANLCWYVVNBGEE-IDIVVRGQSA-L
CHEBI:184785
DISODIUM INOSINATE [MART.]
DISODIUM INOSINATE [USP-RS]
DISODIUM INOSINATE [WHO-DD]
Inosine-5'-monophosphateDisodiumSalt
AKOS015896269
AKOS015918501
AKOS024282555
DISODIUM 5'-INOSINATE [FHFI]
CCG-268550
E 631 (FOOD ENHANCEMENT AGENT)
Inosine monophosphate disodium [WHO-DD]
[(3S,2R,4R,5R)-3,4-dihydroxy-5-(6-oxohydropurin-9-yl)oxolan-2-yl]methyl dihydr ogen phosphate, sodium salt, sodium salt
AS-57564
E 631
E-631
I0036
Q905782
14999-51-0
disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)oxolan-2-yl]methyl phosphate
sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-2-yl)methyl phosphate
DISODIUM LAURETH SULFOSUCCINATE
Disodium laureth sulfosuccinate is a cleansing agent found in products such as face wash, bubble bath, and shampoo, as well as other personal care products.
Disodium laureth sulfosuccinate can help boost the foaming properties of such formulas plus enhance the water solubility of other surfactants.
Suppliers of Disodium laureth sulfosuccinate note its gentleness on skin.

CAS: 40754-59-4
MF: C22H43NaO10S
MW: 522.63
EINECS: 255-062-3

Synonyms
2-(Sodiooxysulfonyl)-4-(3,6,9-trioxahenicosane-1-yloxy)-4-oxobutanoic acid sodium salt;2-(Sodiosulfo)butanedioic acid 1-sodium 4-[2-[2-[2-(dodecyloxy)ethoxy]ethoxy]ethyl] ester salt;2-(Sodiosulfo)butanedioic acid 4-[2-[2-[2-(dodecyloxy)ethoxy]ethoxy]ethyl]1-sodium salt;Einecs 255-062-3;Sulfobutanedioic acid, 4-(2-(2-(2-(dodecyloxy)ethoxy)ethoxy)ethyl) ester, disodium salt;disodium 4-(2-(2-(2-(dodecyloxy)ethoxy)ethoxy)ethyl) 2-sulphonatosuccinate;DISODIUM LAURETH SULFOSUCCINATE;JACS-40754-59-4

Disodium laureth sulfosuccinate can be sourced naturally (plant derived) or synthetically (lab created).
Disodium laureth sulfosuccinate is described as a clear, colorless to slightly yellowish liquid in raw material form.
Technically speaking, Disodium laureth sulfosuccinate is the disodium salt of an ethoxylated lauryl alcohol half ester of sulfosuccinic acid.
Disodium laureth sulfosuccinate is a cleansing agent or a surfactant commonly found in shampoos and hair cleansing formulas.
Disodium laureth sulfosuccinate is a mild, anionic, and non-irritating surfactant but has great foaming properties.
Disodium laureth sulfosuccinate has been recommended for use in gentle cleansers and for babies or sensitive skin.

Disodium laureth sulfosuccinate is a compound in which the sulfate ion has been replaced by a sulfonated ester, thus providing a safe, effective, and non-irritating cleanser.
As opposed to sulfates which are small molecules, Disodium laureth sulfosuccinate is a large molecule that cannot penetrate into the scalp or skin.
Disodium laureth sulfosuccinate is found in low concentrations in toothpaste, shampoos, shaving creams, and bubble bath formulations for its foaming and surfactant properties and for its thickening ability.
In shampoos, Disodium laureth sulfosuccinate provides mild cleansing and rich lathering properties, without stripping the moisture from the hair.
Disodium laureth sulfosuccinate should not exceed the concentration of 1% in products intended for prolonged skin contact.
Disodium laureth sulfosuccinate is a sodium salt of the sulfosuccinic acid that is used as a foaming agent and cleanser.
Disodium laureth sulfosuccinate can be found in many household products, such as shampoos, detergents, and toothpaste.
Disodium laureth sulfosuccinate is also used to cleanse wounds, ulcers, and burns.
Disodium laureth sulfosuccinate has been shown to be effective in treating alopecia areata by inhibiting the growth of cells responsible for hair follicle destruction.

Disodium Laureth Sulfosuccinate is a cleansing chemical which is also known as a surfactant.
However, Disodium laureth sulfosuccinate is not considered to be a sulfate.
Disodium laureth sulfosuccinate is a usual chemical found in some ‘greener’ or more natural formulas which is used to replace the harsher sulfates owning to its non-irritating yet effective characteristics.
Disodium Laureth Sulfosuccinate can be found in many shampoo and cleansing formulas and it is utilized for its degreasing, foaming, and emulsifying benefits.
Disodium laureth sulfosuccinate is considered to be extremely gentle to the skin and hair even at higher concentrations.

Disodium Laureth Sulfosuccinate has excellent washing, emulsifying, dispersing, wetting and solubilizing abilities;
At the same time, Disodium laureth sulfosuccinate has relatively very low irritation, good compatibility and is able to significantly control the irritation of other surfactants;
The foam formed by Disodium Laureth Sulfosuccinate is fine and stable; low surface tension and excellent calcium soap dispersion;
What is more, Disodium Laureth Sulfosuccinate has excellent anti-hard water performance, low degreasing power, moderate detergency, easy to rinse and no slippery feeling.

Disodium laureth sulfosuccinate Chemical Properties
Boiling point: 100℃[at 101 325 Pa]
Density: 1.165[at 20℃]
Vapor pressure: 0Pa at 25℃
Water Solubility: 120.9μg/L at 25℃
LogP: 3.66
CAS DataBase Reference: 40754-59-4

1. Enhance the attached components in shampoo, and reduction the hair fading rate
2. Extremely mild to skin and hair.
Low irritation, and reduce the irritation of other surfactants.
3. Good ability of dispersing calcium soap and anti-hard water.
4.Be compatible with wide range ofsurfactants and plant extracts (such as gleditsia), and easy to form a very stable system
5. Easy to rinse, and reduce the smoothness of detergent.

Uses
Disodium laureth sulfosuccinate is a very mild surfactant, appropriate for baby and child care products.
Disodium laureth sulfosuccinate reduces the irritation properties of high-foaming surfactants when used in the same product formulation.
Disodium Laureth Sulfosuccinate or DLS is a cleansing ingredient that’s used to help improve the cleansing abilities of our products.
Disodium laureth sulfosuccinate's non harsh approach to cleansing is a 180° difference to other cleansing ingredients, like sulfates.
But Disodium laureth sulfosuccinate's ability to be mild but effective is why we use it.
Disodium laureth sulfosuccinate is not a sulfate, while the name may seem similar to sulfates, it’s not.
Names can be deceiving.

Disodium laureth sulfosuccinate is quite gentle to skin.
Even of high consistence, Disodium laureth sulfosuccinate still remains low irritation.
Disodium laureth sulfosuccinate also has good cleaning ability, resistance to hard water, medium foaming ability, easiness of rinsing, good smoothness and biodegradation.
Meanwhile, Disodium laureth sulfosuccinate owns perfect solubilising and viscosity adjusting functions.
In liquid washing products, Disodium laureth sulfosuccinate will reduce the irritation of other anionic surfactants.
With medium cleaning ability and weak degreasing force, Disodium laureth sulfosuccinate is applicable in shampoo, bubble bath, facial cleanser, hand cleaner, dishware detergent, and detergent of down clothes.
Disodium laureth sulfosuccinate is especially suitable for confection of baby washing products of low irritation.
Disodium laureth sulfosuccinate can also be used as industrial liquid detergent.
DISODIUM LAURETH SULFOSUCCINATE (DLS)
Disodium laureth sulfosuccinate (DLS) is a cleansing ingredient that is used to help improve the cleansing abilities of skincare products.
Disodium laureth sulfosuccinate (DLS) is generally considered to be less harsh than other cleansing ingredients such as sulfates.
Disodium laureth sulfosuccinate (DLS) is a common ingredient in shampoos, cleansers, and body washes.

CAS: 39354-45-5
MF: C16H28Na2O7S
MW: 410.43

Disodium laureth sulfosuccinate (DLS) is mainly due to its ability to lift oils and dirt from the skin, allowing them to be easily rinsed away.
Disodium laureth sulfosuccinate (DLS) also helps to improve the foaming of the product and helps to stabilize the product.
Disodium laureth sulfosuccinate (DLS) is a surfactant.
Surfactants lower the surface tension between two liquids or solids.
Disodium laureth sulfosuccinate (DLS) allows for oils and dirt to be lifted from the skin and be easily washed away from the skin.
This is why Disodium laureth sulfosuccinate (DLS) is primarily used in cleansers, soaps, bubble bath products, shampoos, and shaving creams.

Disodium laureth sulfosuccinate (DLS) is considered to be gentler on the skin.
Disodium laureth sulfosuccinate (DLS) is due to the molecule size, other surfactants have smaller molecule sizes while DLS has a larger molecule size comparatively.
This means that Disodium laureth sulfosuccinate (DLS) doesn’t readily penetrate the skin where it is likely to cause irritation.
Disodium laureth sulfosuccinate (DLS) also is a negatively charged molecule, contributing to its milder nature.
Disodium laureth sulfosuccinate (DLS) is a sodium salt of the sulfosuccinic acid that is used as a foaming agent and cleanser.

Disodium laureth sulfosuccinate (DLS) can be found in many household products, such as shampoos, detergents, and toothpaste.
Disodium laureth sulfosuccinate (DLS) is also used to cleanse wounds, ulcers, and burns.
Disodium laureth sulfosuccinate (DLS) has been shown to be effective in treating alopecia areata by inhibiting the growth of cells responsible for hair follicle destruction.
Disodium laureth sulfosuccinate (DLS) is synthesized by treating lauryl alcohol with sulfur trioxide gas, oleum, or chlorosulfuric acid to produce hydrogen lauryl sulfate.
The resulting product is then neutralized by the addition of sodium hydroxide or sodium carbonate.

Disodium laureth sulfosuccinate (DLS) Chemical Properties
Melting Point: N/A
Boiling Point: °Cat760mmHg
Flash Point: °C
Appearance: /Density: g/cm3
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Disodium laureth sulfosuccinate (DLS) (CAS DataBase Reference)
NIST Chemistry Reference: Disodium laureth sulfosuccinate (DLS) (39354-45-5)
EPA Substance Registry System: Disodium laureth sulfosuccinate (DLS)(39354-45-5)

Use
Disodium laureth sulfosuccinate (DLS) is found in low concentrations in toothpaste, shampoos, shaving creams, and bubble bath formulations for its foaming and surfactant properties and for its thickening ability.
In shampoos, Disodium laureth sulfosuccinate (DLS) provides mild cleansing and rich lathering properties, without stripping the moisture from the hair.
Disodium laureth sulfosuccinate (DLS) should not exceed the concentration of 1% in products intended for prolonged skin contact.

Disodium laureth sulfosuccinate (DLS) is an important ingredient added to cosmetic formulations, which improves the clarity of a product and helps dissolve other components in the cosmetic.
Disodium laureth sulfosuccinate (DLS) has very good foaming properties: it helps generate good quality stable foams in a mixture with non-ionic surfactants.
Thus the cosmetic products that contain Disodium laureth sulfosuccinate (DLS) are mostly dedicated for washing and/or cleaning applications.
Disodium laureth sulfosuccinate (DLS) features very good skin and hair degreasing properties.
Disodium laureth sulfosuccinate (DLS) is a detergent used in the production of face, body and hair wash preparations.
You can find Disodium laureth sulfosuccinate (DLS) in rinse-off cosmetics such as shampoos, shower gels or hand soaps.

Moreover, Disodium laureth sulfosuccinate (DLS) is used as an ingredient in hair care products including sprays or tints.
Disodium laureth sulfosuccinate (DLS) is suitable for use in cosmetic formulations for the care of sensitive skin; its molecules are large enough to prevent the surfactant from penetrating the skin.
In addition, Disodium laureth sulfosuccinate (DLS) is capable of reducing the irritating effects of SLES.
Note that Disodium laureth sulfosuccinate (DLS) may be an ingredient of both preparations that contain SLES and those that are SLES free.

Disodium laureth sulfosuccinate (DLS) can be widely used in shampoo, bubble bath, facial cleaner, hand washing, dishware detergent.
Disodium laureth sulfosuccinate (DLS) is especially suitable for confection of baby washing products of low irritation.
In addition, owning to Disodium laureth sulfosuccinate (DLS)'s good lubrication and resistance to hard water, and excellent solubilising performance.
Disodium laureth sulfosuccinate (DLS) can also be used as industrial liquid detergent.
The recommended dosage is: 0.5%~20%

The Disodium laureth sulfosuccinate (DLS) is a top choice for making any number of products where a natural focus is desired.
Disodium Laureth Sulfosuccinate, also known as DLS, or DLS mild, is the perfect choice for making non irritating natural products - from ultra mild shampoos, products for sensitive skin, baby products, facial products and so many other gentle and natural hair care and skin care products.
Since the Disodium laureth sulfosuccinate (DLS) is non-irritating and doesn't strip hair or skin of their natural oils, and cleans effectively, the skin and hair are left feeling soft and conditioned after rinse off of the formulated product.

Characteristics
1. Delicate white paste in room temperature, when heated to (70C) and become transparent liquid
2. Rich and fine foam, easy to wash and no creamy feeling
3. Excellent cleaning ability, Low degreasing ability and mild to skin..
4. Be compatible with other surfactant, and reduce irritation of other surfactants.
5. Excellent anti-hard water and biodegradable ability, High cost performance

Synonyms
39354-45-5
94108-10-8
Disodium 4-(2-(dodecyloxy)ethyl) 2-sulphonatosuccinate
EINECS 302-348-1
alt(70%)
SCHEMBL674038
4-(2-dodecoxyethoxy)-4-oxo-2-sulfonatobutanoate Disodium
DTXSID20873839
DISODIUM 4-[2-(DODECYLOXY)ETHOXY]-4-OXO-2-SULFONATOBUTANOATE
2-(Sodiooxysulfonyl)butanedioic acid 1-sodium 4-[2-(dodecyloxy)ethyl] ester salt
DNS-330
DISODIUM LAURYL SULFOSUCCINATE
DISODIUM 4-LAURETH SULFOSUCCINATE
Lauryl sulfosuccinate disodium salt
LAURETH SULFOSUCCINATE DISODIUM SALT
Dodecyl sulfosuccinate, disodium salt
LAURYL ETHER SULFOSUCCINATE DISODIUM SALT
DODECYL ETHER SULFOSUCCINATE DISODIUM SALT
SULPHOSUCCINICACID4-ESTERWITHPOLYETHYLENEGLYCOLDODEC
SULPHOSUCCINICACID4-ESTERWITHPOLYETHYLENEGLYCOLDODEC.
Poly(oxy-1,2-ethanediyl), .alpha.-(3-carboxy-1-oxo-3-sulfopropyl)-.omega.-(dodecyloxy)-, disodium salt
DISODIUM LAURETH SULFOSUCCINATE DLS
DESCRIPTION:
Disodium laureth sulfosuccinate (DLS) is a cleansing agent or a surfactant commonly found in shampoos and hair cleansing formulas.
Disodium laureth sulfosuccinate (DLS) is a mild, anionic, and non-irritating surfactant but has great foaming properties.
Disodium laureth sulfosuccinate (DLS) has been recommended for use in gentle cleansers and for babies or sensitive skin.

CAS No.: 19040-44-9
Molecular formula: C12H25OOCCH2CH(SO3Na)COONa


Disodium Laureth Sulfosuccinate (DLS) CAS 36409-57-1 is a cleansing chemical which is also known as a surfactant.
However, Disodium Laureth Sulfosuccinate (DLS) is not considered to be a sulfate.
Disodium Laureth Sulfosuccinate (DLS) is a usual chemical found in some ‘greener’ or more natural formulas which is used to replace the harsher sulfates owning to its non-irritating yet effective characteristics.

Disodium Laureth Sulfosuccinate (DLS) CAS 36409-57-1 can be found in many shampoo and cleansing formulas and it is utilized for its degreasing, foaming, and emulsifying benefits.
Disodium Laureth Sulfosuccinate (DLS) is considered to be extremely gentle to the skin and hair even at higher concentrations.

Disodium Laureth Sulfosuccinate (DLS) CAS 36409-57-1 has excellent washing, emulsifying, dispersing, wetting and solubilizing abilities;

At the same time, Disodium Laureth Sulfosuccinate (DLS) has relatively very low irritation, good compatibility and is able to significantly control the irritation of other surfactants;

The foam formed by Disodium Laureth Sulfosuccinate (DLS) CAS 36409-57-1 is fine and stable; low surface tension and excellent calcium soap dispersion;

What is more, Disodium Laureth Sulfosuccinate (DLS) CAS 36409-57-1 has excellent anti-hard water performance, low degreasing power, moderate detergency, easy to rinse and no slippery feeling.


Disodium laureth sulfosuccinate known as DLS is a very mild cleansing agent and anionic surfactant that is non-irritating, with great foam properties.
Disodium laureth sulfosuccinate is a suitable replacement for sulfate-free formulations.

DLS Mild can be used as the primary or Secondary Surfactant.
Suitable for mild shampoos, body, baby, and facial wash.


Disodium Laureth Sulfosuccinate (DLS) possesses excellent emulsification, dispersion, wetting and solubilizing performance.
Disodium Laureth Sulfosuccinate (DLS) is quite gentle to skin even in high consistence.
Disodium Laureth Sulfosuccinate (DLS) Offers low irritation and markedly reducing the irritation of other surfactants.
Disodium Laureth Sulfosuccinate (DLS) Exhibits medium decontamination and low degreasing power.

Disodium Laureth Sulfosuccinate (DLS) Provides excellent cleaning ability and easy to rinse.
Disodium Laureth Sulfosuccinate (DLS) Has good efficiency of dispersing calcium soap and anti-hard water.

Disodium Laureth Sulfosuccinate (DLS) Enhances the attached components in shampoo, and reducing the hair color fading rate.
Disodium Laureth Sulfosuccinate (DLS) imparts medium foaming property, perfect solubility and viscosity adjusting functions.
Disodium Laureth Sulfosuccinate (DLS) is Used in shampoos, bubble-bath liquid, hand washing, facial cleanser.

Disodium Laureth Sulfosuccinate (DLS), also known as Disodium Lauryl Ether Sulfosuccinate, is an anionic surfactant primarily introduced in 1939.
DLS belongs to a greater group of surfactants called Sulfosuccinates, the sodium salts of alkyl esters of sulfosuccinic acid.

Disodium Laureth Sulfosuccinate is of great interest because of its excellent properties, such as good cleansing, lathering, emulsifying, and biodegradability.
DLS is considered a mild and effective ingredient in cosmetic and hygiene products.
The mildness of this compound makes it a proper choice, even for baby cleansing products.

Today, DLS is used not only in cleansing formulations but also in various industries, including textiles, polymers, paints and coating, leather, printing, and agriculture.


IS DISODIUM LAURETH SULFOSUCCINATE A SULFATE?
No. Disodium laureth sulfosuccinate (DLS) is a compound in which the sulfate ion has been replaced by a sulfonated ester, thus providing a safe, effective, and non-irritating cleanser.
As opposed to sulfates which are small molecules, disodium laureth sulfosuccinate is a large molecule that cannot penetrate into the scalp or skin.


USES OF DISODIUM LAURETH SULFOSUCCINATE (DLS):
Disodium laureth sulfosuccinate is found in low concentrations in toothpaste, shampoos, shaving creams, and bubble bath formulations for its foaming and surfactant properties and for its thickening ability.
In shampoos, Disodium laureth sulfosuccinate (DLS) provides mild cleansing and rich lathering properties, without stripping the moisture from the hair.
Disodium laureth sulfosuccinate (DLS) should not exceed the concentration of 1% in products intended for prolonged skin contact.

Disodium Laureth Sulfosuccinate (DLS) CAS 36409-57-1 is widely used in the preparation of shampoos, facial cleansers, shower gels, hand sanitizers, surgical cleaning agents and other daily cleaning products.
Disodium Laureth Sulfosuccinate (DLS) is also able to be utilzied as an emulsifier in the emulsion polymerization industry, as well.









ORIGIN OF DISODIUM LAURETH SULFOSUCCINATE (DLS):
Disodium laureth sulfosuccinate is synthesized by treating lauryl alcohol with sulfur trioxide gas, oleum, or chlorosulfuric acid to produce hydrogen lauryl sulfate.
The resulting product is then neutralized by the addition of sodium hydroxide or sodium carbonate.


CHEMICAL AND PHYSICAL PROPERTIES OF DISODIUM LAURETH SULFOSUCCINATE DLS:
Melting Point 153-157°C
pH 5.5-6.2 (10% solution in water)
Solubility Slightly soluble in water
Disodium laureth sulfosuccinate
Lauryl sulfosuccinate disodium salt ethoxylated with 3 mol EO, DLS, Butanedioic acid,2-sulfo-, 1-dodecyl ester, sodium salt (1:2)
Formula: C16H28Na2O7S
IUPAC: disodium4-dodecoxy-4-oxo-3-sulfonatobutanoate
INCI: Disodium Laureth Sulfosuccinate
CAS: 39354-45-5
Molar mass: 410.4
Density: 1,10 g/mL 20 °C
Solubility : Miscible in water, mixes well with most polar solvents.


As stated earlier, DLS belongs to Sulfosuccinate monoesters.
These compounds, like other surfactants, contain a hydrophobic head that is derived from a fatty alcohol molecule.
This nonpolar head may be ethoxylated and have several PEG (polyethylene glycol) units, or it can be saturated.

This slight difference in molecular structure may result in different water solubility potentials.
For instance, the ethoxylated compounds are more soluble.
Water solubility is also increased when the structure contains branched chains.

Disodium Laureth Sulfosuccinate (DLS) consists of a twelve-carbon alkyl chain (lauryl), connected to the sulfosuccinate core via a PEG chain.
The average number of ethoxy repeat units (n) in this chain is between 1 and 4 (i.e., Laureth-1 through Laureth-4).




SAFETY INFORMATION ABOUT DISODIUM LAURETH SULFOSUCCINATE DLS:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product









SYNONYMS OF DISODIUM LAURETH SULFOSUCCINATE (DLS):
Disodium Fatty Alcohol Polyoxyethylene Ether Sulfosuccinate
DODECYL ETHER SULFOSUCCINATE DISODIUM SALT;
Butanedioic acid,(dodecyloxy)sulfonyl-,disodium salt;
disodium [(dodecyloxy)sulphonyl]succinate;
Butanedioic acid,sulfo-,4-2-2-2-(dodecyloxy)ethoxyethoxyethyl ester,disodium salt;
DISODIUM LAURYL SULFOSUCCINATE;



DISODIUM LAURETH-7 CITRATE
DISODIUM LAURIMINOBISHYDROXYPROPYLSULFONATE N° CAS : 4055-91-8 Nom INCI : DISODIUM LAURIMINOBISHYDROXYPROPYLSULFONATE Nom chimique : 1-Propanesulfonic Acid, 3,3'-(Dodecylimino)Bis[2-Hydroxy-], Disodium salt Ses fonctions (INCI) Agent nettoyant : Aide à garder une surface propre Agent moussant : Capture des petites bulles d'air ou d'autres gaz dans un petit volume de liquide en modifiant la tension superficielle du liquide Sinergiste de mousse : Améliore la qualité de la mousse produite en augmentant une ou plusieurs des propriétés suivantes: volume, texture et / ou stabilité Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISODIUM LAURIMINOBISHYDROXYPROPYLSULFONATE
DISODIUM LAURIMINODIACETATE, N° CAS : 5931-57-7 / 34359-86-9. Nom INCI : DISODIUM LAURIMINODIACETATE. Nom chimique : Glycine, N-(Carboxymethyl)-N-Dodecyl-, Disodium salt, Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Agent nettoyant : Aide à garder une surface propre. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISODIUM LAURIMINODIACETATE
DISODIUM LAURIMINODIPROPIONATE, N° CAS : 3655-00-3, Nom INCI : DISODIUM LAURIMINODIPROPIONATE. Nom chimique : Disodium N-(2-carboxyethyl)-N-dodecyl-.beta.-alaninate, N° EINECS/ELINCS : 222-899-0. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Agent nettoyant : Aide à garder une surface propre Agent moussant : Capture des petites bulles d'air ou d'autres gaz dans un petit volume de liquide en modifiant la tension superficielle du liquide. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISODIUM LAURIMINODIPROPIONATE
DISODIUM LAUROAMPHODIACETATE, N° CAS : 14350-97-1. Nom INCI : DISODIUM LAUROAMPHODIACETATE. Nom chimique : Disodium 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-undecyl-1H-imidazolium hydroxide. N° EINECS/ELINCS : 238-306-3.Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Agent nettoyant : Aide à garder une surface propre Agent moussant : Capture des petites bulles d'air ou d'autres gaz dans un petit volume de liquide en modifiant la tension superficielle du liquide Sinergiste de mousse : Améliore la qualité de la mousse produite en augmentant une ou plusieurs des propriétés suivantes: volume, texture et / ou stabilité Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance Hydrotrope : Augmente la solubilité d'une substance qui est peu soluble dans l'eau. 1H-imidazolium, 1-(2-(carboxymethoxy)ethyl)-1-(carboxymethyl)-4,5-dihydro-2-undec- yl-, hydroxide, disodium salt 1H-imidazolium, 1-(2-(carboxymethoxy)ethyl)-1-(carboxymethyl)-4,5-dihydro-2-undecyl-, hydroxide, disodium salt 2-[1-[2-(carboxylatomethoxy)ethyl]-2-undecyl-4,5-dihydroimidazol-1-ium-1-yl]acetate hydroxide 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol, dicarboxymethylated, disodium salt disodium 1-(2-(carboxymethoxy)ethyl)-1-(carboxymethyl)-4,5-dihydro-2-undecyl-1H-imidazolium hydroxide lauroamphocarboxyglycinate disodium;3-[1-[2-(2-carboxylatoethoxy)ethyl]-2-undecyl-4,5-dihydroimidazol-1-ium-1-yl]propanoate;hydroxide miranol H2M Conc sodium hydroxide{1-[2-(carboxylatomethoxy)ethyl]-2-undecyl-4,5-dihydro-1h-imidazol-1-ium-1-yl}acetate(2:1:1) TC-MAB 40LDL Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques; Disodium lauroamphodiacetate; Lauroamphocarboxyglycinate
DISODIUM LAURIMINODIPROPIONATE

Disodium lauriminodipropionate is a chemical compound used primarily in personal care products and cosmetics.
Disodium lauriminodipropionate is a surfactant, which means it has both hydrophilic (water-attracting) and lipophilic (fat-attracting) properties.
Disodium lauriminodipropionate is often added to cleansing products such as shampoos, body washes, and facial cleansers due to its ability to effectively remove dirt, oil, and other impurities from the skin and hair.

CAS Number: 3655-00-3
EC Number: 222-899-0

Disodium lauriminodipropionate, Lauriminodipropionic Acid Disodium Salt, Lauriminodipropionic Acid Sodium Salt, Sodium Lauriminodipropionate, Disodium Lauroamphoacetate, Disodium Cocoamphodipropionate, Disodium Hydroxyethyliminodipropionate, Disodium Lauroamphodiacetate, Lauramidopropyl Betaine, Disodium Laureth Sulfosuccinate, Sodium Lauroyl Glutamate, Disodium Cocoamphodiacetate, Disodium Lauroamphopropionate, Disodium Lauryl Sulfosuccinate, Disodium Lauroamphoglycinate, Disodium Lauroamphopropionic Acid, Disodium Cocamphodiacetate, Disodium Cocoamphodipropionate, Disodium Cocoamphopropionate, Disodium Lauramphodiacetate, Disodium Lauramphopropionate, Disodium Laureth Sulfate, Disodium Laureth Sulfosuccinate, Disodium Myreth Sulfosuccinate, Disodium Oleamphodiacetate, Disodium Oleamphodipropionate, Disodium Oleamphopropionate, Disodium Palmitamidopropyltrimonium Chloride, Disodium PEG-12 Dimethicone Sulfosuccinate, Disodium PEG-20 Methyl Glucose Dioleate, Disodium PEG-30 Dipolyhydroxystearate, Disodium PEG-8 Laurate, Disodium PEG-8 Ricinoleate, Disodium PEG-8 Sulfosuccinate, Disodium PEG-8 Tocopheryl Sulfate, Disodium PEG-9 Cocamide Sulfosuccinate, Disodium PEG-9 Lauryl Ether Sulfosuccinate, Disodium PEG-9 Polydimethylsiloxyethyl Dimethicone Sulfosuccinate, Disodium PEG-9 Polydimethylsiloxyethyl Dimethicone Sulfosuccinate



APPLICATIONS


Disodium lauriminodipropionate is commonly used as a primary surfactant in shampoo formulations.
Disodium lauriminodipropionate helps to create a rich and foamy lather that effectively cleanses the scalp and hair.

Disodium lauriminodipropionate is found in various types of body washes and shower gels, where it contributes to thorough yet gentle cleansing of the skin.
Disodium lauriminodipropionate is often included in facial cleansers and makeup removers for its ability to remove dirt, oil, and makeup residue from the skin.
Disodium lauriminodipropionate is utilized in hand soaps and liquid hand washes to provide effective cleansing and sanitation of the hands.

Disodium lauriminodipropionate is added to baby washes and cleansers for its mild and gentle cleansing properties, suitable for delicate baby skin.
Disodium lauriminodipropionate is incorporated into facial cleansers targeted at individuals with sensitive or acne-prone skin, as it helps to remove impurities without causing irritation.
Disodium lauriminodipropionate is included in bubble bath formulations to create luxurious and bubbly foam for a relaxing bathing experience.

Disodium lauriminodipropionate is used in intimate washes and feminine hygiene products for its cleansing and soothing properties in sensitive areas.
Disodium lauriminodipropionate is found in shaving creams and gels, where it helps to lubricate the skin and soften the hair for a smooth shave.

Disodium lauriminodipropionate is added to facial scrubs and exfoliating cleansers to enhance their cleansing efficacy and exfoliating action.
Disodium lauriminodipropionate is utilized in acne treatment products such as facial washes and cleansers to help clear and prevent breakouts.

Disodium lauriminodipropionate is incorporated into pet shampoos and grooming products for effective cleansing and odor control in animals.
Disodium lauriminodipropionate is included in scalp treatments and anti-dandruff shampoos for its cleansing and scalp-soothing properties.

Disodium lauriminodipropionate is found in children's bath products such as bubble baths and bath washes, formulated to be gentle on sensitive skin.
Disodium lauriminodipropionate is utilized in antibacterial hand washes and sanitizers for its cleansing and germ-fighting properties.
Disodium lauriminodipropionate is added to foot scrubs and exfoliating cleansers to help remove dead skin cells and soften rough areas on the feet.

Disodium lauriminodipropionate is incorporated into pre-shave cleansers and facial washes to prepare the skin for a close and comfortable shave.
Disodium lauriminodipropionate is used in hair coloring products such as hair dyes and bleaches to help remove excess dye and residues from the scalp and hair.
Disodium lauriminodipropionate is found in sun care products such as sunscreen lotions and creams, where it helps to remove sunscreen residues and sweat from the skin after sun exposure.

Disodium lauriminodipropionate is included in antifungal body washes and cleansers for its cleansing and antifungal properties in treating fungal infections.
Disodium lauriminodipropionate is utilized in post-workout cleansers and body washes to remove sweat, dirt, and odor from the skin after exercise.

Disodium lauriminodipropionate is added to deodorant body washes and cleansers for effective odor control and long-lasting freshness.
Disodium lauriminodipropionate is found in travel-size cleansing wipes and towelettes for convenient on-the-go cleansing and refreshing.
Disodium lauriminodipropionate is incorporated into specialty cleansing products such as micellar water and oil cleansers for thorough yet gentle makeup removal and skin cleansing.

Disodium lauriminodipropionate is used in facial toners and astringents to help remove residual impurities and tighten pores.
Disodium lauriminodipropionate is found in exfoliating body scrubs and cleansers to promote smoother, softer skin by removing dead skin cells.

Disodium lauriminodipropionate is included in anti-aging skincare products such as cleansers and serums to help improve skin texture and tone.
Disodium lauriminodipropionate is utilized in body polishes and buffing creams to gently slough away rough patches and reveal brighter skin.
Disodium lauriminodipropionate is added to clay masks and purifying cleansers to help draw out impurities and excess oil from the skin.

Disodium lauriminodipropionate is found in oil-based cleansers and makeup removers, where it effectively lifts away waterproof makeup and sunscreen.
Disodium lauriminodipropionate is incorporated into facial mists and sprays to refresh and hydrate the skin throughout the day.
It is used in facial cleansing wipes and towelettes for quick and convenient makeup removal and cleansing on-the-go.

Disodium lauriminodipropionate is included in scalp scrubs and detoxifying cleansers to remove product buildup and impurities from the scalp.
Disodium lauriminodipropionate is utilized in facial peels and chemical exfoliants to promote cell turnover and reveal smoother, more radiant skin.

Disodium lauriminodipropionate is added to micellar cleansing waters and solutions for gentle and effective makeup removal without the need for rinsing.
Disodium lauriminodipropionate is found in facial massage creams and cleansers to facilitate smooth and effortless massage movements.
Disodium lauriminodipropionate is incorporated into multi-purpose cleansing balms and oils for makeup removal, cleansing, and hydration in one step.

Disodium lauriminodipropionate is used in body washes and cleansers for men, providing effective cleansing and a refreshing scent.
Disodium lauriminodipropionate is included in post-sun exposure cleansers and cooling gels to soothe and hydrate sun-exposed skin.
Disodium lauriminodipropionate is utilized in bath oils and soak solutions for moisturizing and softening the skin during bathing.

Disodium lauriminodipropionate is added to gentle baby cleansing products such as baby shampoos and washes for mild and tear-free cleansing.
Disodium lauriminodipropionate is found in facial serums and treatment cleansers to enhance the penetration of active ingredients into the skin.
Disodium lauriminodipropionate is incorporated into clarifying shampoos and scalp treatments to remove product residue and excess oil from the scalp.

Disodium lauriminodipropionate is used in cuticle removers and nail cleansers to soften and remove excess cuticle around the nails.
This compound is included in foot soak solutions and foot scrubs for cleansing and softening rough skin on the feet.

Disodium lauriminodipropionate is utilized in body acne cleansers and treatments to help unclog pores and reduce acne breakouts.
Disodium lauriminodipropionate is added to anti-itch creams and cleansers for soothing relief from insect bites, rashes, and skin irritations.

Disodium lauriminodipropionate is found in oil-free cleansers and mattifying products for oily and acne-prone skin types.
Disodium lauriminodipropionate is incorporated into sensitive skin cleansers and barrier repair products to cleanse without stripping the skin of its natural oils.



DESCRIPTION


Disodium lauriminodipropionate is a chemical compound used primarily in personal care products and cosmetics.
Disodium lauriminodipropionate is a surfactant, which means it has both hydrophilic (water-attracting) and lipophilic (fat-attracting) properties.
Disodium lauriminodipropionate is often added to cleansing products such as shampoos, body washes, and facial cleansers due to its ability to effectively remove dirt, oil, and other impurities from the skin and hair.

Disodium lauriminodipropionate is a mild and gentle surfactant commonly used in personal care products.
Disodium lauriminodipropionate has a clear or pale yellow appearance and a mild characteristic odor.
Disodium lauriminodipropionate is derived from lauric acid, a fatty acid found in coconut oil or palm kernel oil.

Disodium lauriminodipropionate is produced through a reaction between lauric acid and dipropylene glycol, followed by neutralization with sodium hydroxide to form the disodium salt.
Disodium lauriminodipropionate is known for its excellent cleansing properties, effectively removing dirt, oil, and other impurities from the skin and hair.
Disodium lauriminodipropionate produces a rich and creamy lather in personal care formulations, contributing to the sensory experience of cleansing products.

Despite its strong cleansing power, Disodium lauriminodipropionate is gentle on the skin and hair, making it suitable for use in products for sensitive skin types.
Disodium lauriminodipropionate helps to maintain the natural moisture balance of the skin and hair, preventing dryness and irritation.
Disodium lauriminodipropionate may also function as a conditioning agent, leaving the skin and hair feeling soft, smooth, and moisturized after use.

Disodium lauriminodipropionate is commonly found in shampoos, body washes, facial cleansers, and other skincare and hair care products.
Disodium lauriminodipropionate contributes to the overall effectiveness of cleansing formulations, ensuring thorough yet gentle removal of impurities.

Disodium lauriminodipropionate helps to create stable emulsions and suspensions in personal care products, enhancing their stability and shelf life.
Disodium lauriminodipropionate exhibits good compatibility with a wide range of other ingredients and additives commonly used in cosmetic formulations.

Disodium lauriminodipropionate is non-toxic and non-irritating when used in recommended concentrations, posing minimal risk of adverse effects on the skin and hair.
Disodium lauriminodipropionate has a neutral pH and is suitable for use in formulations with a wide range of pH levels.

Disodium lauriminodipropionate is soluble in water and miscible with most organic solvents, facilitating its incorporation into various types of cosmetic formulations.
Disodium lauriminodipropionate is stable under a wide range of temperatures, maintaining its effectiveness during storage and use.

Disodium lauriminodipropionate does not undergo significant degradation or decomposition under normal handling and storage conditions.
Disodium lauriminodipropionate is biodegradable, breaking down into harmless substances in the environment over time.

Disodium lauriminodipropionate is produced and used in accordance with industry standards and regulatory guidelines for cosmetic ingredients.
Disodium lauriminodipropionate is often included in formulations targeted at individuals with sensitive or delicate skin, offering gentle yet effective cleansing.
Disodium lauriminodipropionate helps to remove makeup, dirt, and excess oil from the skin without stripping away its natural oils or causing irritation.



PROPERTIES


Molecular Weight: 373.4 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 15
Exact Mass: 373.22049710 g/mol
Monoisotopic Mass: 373.22049710 g/mol
Topological Polar Surface Area: 83.5Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 278
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes



FIRST AID


Inhalation:

If inhaled, remove the affected person to a well-ventilated area with fresh air.
Allow the individual to rest in a comfortable position and keep them warm and calm.
If breathing is difficult, administer oxygen if available, and seek medical attention immediately.
In case of respiratory distress or if breathing has stopped, administer artificial respiration or cardiopulmonary resuscitation (CPR) as necessary.


Skin Contact:

Immediately remove contaminated clothing and footwear.
Wash the affected skin thoroughly with soap and water for at least 15 minutes.
If irritation, redness, or rash develops, seek medical advice or consult a physician.
If irritation persists or worsens, seek medical attention promptly.
Avoid further exposure to the substance and prevent re-contamination of the skin.


Eye Contact:

Flush the affected eye(s) with lukewarm water or saline solution for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Remove contact lenses if present and easy to do so, but do not forcibly remove them if they are stuck to the eye.
Seek immediate medical attention or consult an eye care professional.
Provide relevant information about the substance to medical personnel for appropriate treatment.


Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth thoroughly with water and drink plenty of water to dilute the substance.
Seek immediate medical attention or contact a poison control center for guidance.
Provide information about the ingested substance and its container to medical personnel for proper evaluation and treatment.
Do not give anything by mouth to an unconscious person.


General First Aid:

If any symptoms persist or worsen after initial first aid measures, seek medical advice promptly.
Keep the individual under observation and monitor vital signs such as breathing, pulse, and consciousness.
Provide supportive care as needed, including rest, hydration, and comfort measures.
Be prepared to provide additional information about the substance and exposure circumstances to medical personnel for proper diagnosis and treatment.
If seeking medical attention, bring the product container or label to assist healthcare professionals in identifying the substance and its potential hazards.



HANDLING AND STORAGE


Handling:

Wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and protective clothing, when handling Disodium lauriminodipropionate.
Avoid direct contact with the eyes, skin, and clothing.
In case of contact, rinse immediately with plenty of water.
Use in a well-ventilated area to minimize inhalation exposure.
If ventilation is inadequate, use respiratory protection (e.g., respirator) as necessary.

Avoid generating dust, aerosols, or mists during handling.
Use engineering controls such as local exhaust ventilation to control airborne concentrations.
Do not eat, drink, or smoke while handling Disodium lauriminodipropionate.

Wash hands thoroughly after handling and before eating, drinking, or using the restroom.
Prevent spills, leaks, and releases of the substance.
Handle containers carefully and avoid rough handling or dropping.

Use appropriate handling equipment (e.g., pumps, funnels) to transfer the substance from one container to another. Do not use compressed air for transfer.
Follow good industrial hygiene practices and established safety procedures when working with Disodium lauriminodipropionate.
Keep containers tightly closed when not in use to prevent contamination and moisture absorption.


Storage:

Store Disodium lauriminodipropionate in a cool, dry, well-ventilated area away from heat, direct sunlight, and sources of ignition.
Keep containers tightly closed and properly labeled to prevent accidental spills and unauthorized access.

Store the substance away from incompatible materials, including strong oxidizing agents, acids, and bases.
Ensure storage areas are equipped with appropriate spill containment and emergency response equipment (e.g., spill kits, eyewash stations, safety showers).
Avoid storing Disodium lauriminodipropionate near food, beverages, or pharmaceuticals to prevent contamination.

Follow manufacturer's recommendations for maximum storage temperature and shelf life of the substance.
Keep storage areas clean and free from clutter to facilitate inspection, maintenance, and emergency response activities.

Regularly inspect containers for signs of damage, leaks, or deterioration.
Replace damaged or compromised containers promptly.
Store Disodium lauriminodipropionate in compliance with applicable regulations and guidelines for the storage of hazardous substances.

Keep storage areas secure and restrict access to authorized personnel only.
Prevent unauthorized access by implementing appropriate security measures.
DISODIUM LAUROAMPHODIACETATE
Nom INCI : DISODIUM LAUROYL GLUTAMATE, Nom chimique : N-(1-Oxododecyl)-L-glutamate disodium salt, Classification : Tensioactif non ionique. Ses fonctions (INCI) :Agent nettoyant : Aide à garder une surface propre Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance Agent d'entretien de la peau : Maintient la peau en bon état Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISODIUM LAUROYL GLUTAMATE
DISODIUM LAURYL SULFOSUCCINATE. N° CAS : 13192-12-6 / 19040-44-9 / 26838-05-1. Nom INCI : DISODIUM LAURYL SULFOSUCCINATE. Nom chimique : Disodium 4-dodecyl 2-sulphonatosuccinate. N° EINECS/ELINCS : 236-149-5 / 248-030-5. Classification : Tensioactif anionique. Le lauryl sulfosuccinate disodique est un tensioactif plus doux que le SLS ou le SLES utilisé principalement dans les shampooings et les produits de bain.Ses fonctions (INCI) Agent nettoyant : Aide à garder une surface propre Agent moussant : Capture des petites bulles d'air ou d'autres gaz dans un petit volume de liquide en modifiant la tension superficielle du liquide Sinergiste de mousse : Améliore la qualité de la mousse produite en augmentant une ou plusieurs des propriétés suivantes: volume, texture et / ou stabilité Hydrotrope : Augmente la solubilité d'une substance qui est peu soluble dans l'eau. Agent d'entretien de la peau : Maintient la peau en bon état Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation; 13192-12-6 [RN] 236-149-5 [EINECS] 4-(Dodécyloxy)-4-oxo-2-sulfonatobutanoate de disodium [French] Butanedioic acid, 2-sulfo-, 4-dodecyl ester, sodium salt (1:2) [ACD/Index Name] Dinatrium-4-(dodecyloxy)-4-oxo-2-sulfonatobutanoat [German] Disodium 4-(dodecyloxy)-4-oxo-2-sulfonatobutanoate DISODIUM 4-LAURYL SULFOSUCCINATE 26838-05-1 [RN] 36409-57-1 [RN] 40754-59-4 [RN] Disodium 2-[(dodecyloxy)sulfonyl]succinate disodium 4-dodecyl 2-sulphonatosuccinate Disodium dodecyl sulphonatosuccinate Disodium laureth sulfosuccinate
DISODIUM LAURYL SULFOSUCCINATE
DISODIUM LAURYL SULFOSUCCINATE;LAURETH SULFOSUCCINATE DISODIUM SALT;disodium [(dodecyloxy)sulphonyl]succinate;LAURYL ETHER SULFOSUCCINATE DISODIUM SALT;DODECYL ETHER SULFOSUCCINATE DISODIUM SALT;Dodecyloxysulfonylsuccinic acid disodium salt;2-(Laurylsulfo)succinic acid 1,4-disodium salt cas no: 36409-57-1
DISODIUM METHYLENE DINAPHTHALENESULFONATE
DISODIUM NADH N° CAS : 606-68-8 Nom INCI : DISODIUM NADH Nom chimique : Adenosine 5'-(Trihydrogen Diphosphate), P'->5'-Ester with 1,4-Dihydro-1- b -D-Ribofuranosyl-3-Pyridinecarboxamide, Disodium Salt Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent d'entretien de la peau : Maintient la peau en bon état
DISODIUM MOLYBDATE
DESCRIPTION:

Disodium molybdate is useful as a source of molybdenum.
This white, crystalline salt is often found as the dihydrate, Na2MoO4·2H2O.
Disodium molybdate is tetrahedral.



CAS NUMBER: 7631-95-0

EC NUMBER: 231-551-7

MOLECULAR FORMULA: MoNa2O4

MOLECULAR WEIGHT: 205.91714



DESCRIPTION:

Disodium molybdate coordinates with every one anion.
Disodium molybdate is white scaly crystal with slight luster, density is 3.2g/cm, soluble in water,can lose water of crystallization at 100°.
Disodium molybdate used in the measurement of acid and alkali,manufacture of alkaloids ,printing ink, fertilizer,raw material for the production of fire retardant.
Disodium molybdate can also be used in circulating cooling system, metal working liquid and other fields as corrosion inh.
Disodium molybdate is one of the transition metals and is silvery white in pure form and very hard.

The melting temperature is quite high.
Further hardening of the steel can be achieved by adding a small amount.
Disodium molybdate is also important in the nutrition of plants and takes place in some enzymes.
Disodium molybdate was first synthesized by the method of hydration.
A more convenient synthesis is done by dissolving MoO3 in sodium hydroxide at 50–70 °C and crystallizing the filtered product.

Disodium molybdate is prepared by heating to 100 °C.
Although Disodium molybdate is found in minerals such as wulfenite (PbMoO4) or powellite (CaMoO4), the main commercial source of molybdenum is molybdenite (MoS2).
Disodium molybdate can also be obtained through direct mining and as a by-product during copper mining.
Disodium molybdate is found in its ores in amounts ranging from 0.01% to 0.5%.
About half of the world's Disodium molybdate mining is done in the USA.

Disodium molybdate is an inorganic sodium salt having molybdate as the counterion.
Disodium molybdate has a role as a poison.
Disodium molybdate contains a molybdate.
Disodium molybdate, which is similar to chromium and wolfram in terms of chemical properties.
Disodium molybdate has superior properties such as high melting and boiling point, high heat resistance, high thermal conductivity and low thermal expansion.

Disodium molybdate melts at 2623 °C.
With this feature, Disodium molybdate takes the sixth place among metals.
Boiling at 4639 °C, Disodium molybdate is not affected by air in the cold, oxidized when incandescent, affected by nitric and sulfuric acids, and decomposes water vapor at high temperatures.
The density of Disodium molybdate is 10.28 gr/cm3.
Disodium molybdate is source of molybdate, ability to stabilize and inhibit the activity of various receptors.
Disodium molybdate is a useful source of molybdate, a Molybdenum (sc-235881) compound.

Disodium molybdate has displayed the ability to stabilize both the androgen and progesterone receptor.
When applied to non-activated estrogen receptors the Disodium Molybdate reversibly inhibited receptor activation.
In the Rat Disodium molybdate inactivated both the active and inactive form of the gluco corticoid receptor complex.
With the use of nitrites, Disodium molybdate salts have been shown to reduce the emission of hydrogen sulphide from swine manure.
Disodium molybdate is an acid phosphatase inhibitor.
The osteoclastic acid phosphatase isoenzyme, secreted by osteoclasts, is a member of a widely-distributed class of iron-containing proteins with acid phosphatase activity.

Elevated plasma isoenzyme levels are associated with increased bone turnover in metabolic disease.
By inhibiting this class of acid phosphatases, sodium molybdate is capable of abolishing bone resorption.
In addition, sodium molybdate has been shown to stabilize the nonactivated glucocorticoid-receptor complex.
Disodium molybdate is a plant micronutrient.

Disodium Molybdate helps convert nitrate to amino acids and proteins.
Disodium molybdate is soluble powder for correcting molybdenum deficiency in plants.
Disodium molybdate can be soil or foliar applied.
Disodium Molybdate is a source of molybdenum.

Disodium molybdate's fundamental role in the human body is as a constituent of molybdoenzymes; some important molybdoenzymes are xanthine oxidase, sulphite oxidase and aldehyde oxidase.
These are involved in the metabolism of sulphur amino acids and purine.
By converting sulphite to sulphate, sulphite oxidase aids the metabolising of the sulphur amino acids methionine and cysteine, a process that is crucial to human health.
Disodium molybdate also helps the body reduce the harmful effects of sulphites generally.
Disodium molybdate is also an essential component of flavin- and iron-containing enzymes.

Disodium molybdate is a white, odourless, free flowing crystalline solid.
Disodium molybdate encourages the creation of a protective oxide film on metal surfaces.
Disodium molybdate is used as a corrosion inhibitor to protect metal surfaces, as it is a non-oxidizing anodic inhibitor.
Disodium molybdate is also used for cooling water systems, engine coolants, metalworking fluids, metal finishing, oil drilling muds and as a fertiliser nutrient.
Disodium molybdate is an essential micronutrient though required by plants in very minute amounts.
Disodium molybdate supports the essential metabolism of nitrogen and synthesis of protein.
Soil that has no Disodium molybdate at all cannot support plant life.

Disodium molybdate is 100% water soluble, compatible in many mixed fertiliser nutrient formulations, easy to apply and importantly easy to clean with no sticky residues.
Most diets will contain a plentiful supply of Disodium molybdate, as it is common in nuts, vegetables and cereals, and is found in drinking water to varying levels.
Each capsule contains about 1mg of molybdenum.
This is a high dose, well in excess of recommended European daily intakes.

Disodium molybdate is recommended not to exceed 1 capsule per day.
Higher intakes of supplemental molybdenum may be better divided into two or three doses through the day.
This is because Disodium molybdate is not accumulated by the body (apart from some accretion in the teeth).
There is believed to be an antagonistic relationship between Disodium molybdate and copper and sulphate.
With high intakes of Disodium molybdate, care should be taken over copper and sulphate levels.

Excessive intake of molybdenum, in excess of 1mg per day, has been reported to cause joint pains, along with increased uric acid levels found in serum.
Long term consumption of higher levels of Disodium molybdate may also have a deactivating effect on glutaminases in the brain and liver, and could reduce the effectiveness of carotenes and vitamin A.
Disodium molybdate is used in the fertilization process of crops as well as the protection from corrosion due to potential construction in a nearby area.,
Disodium molybdate is a clear, colorless, aqueous solution containing at least 35% of Disodium Molybdate represented by the formula: Na2MoO4.
Its applications include scale deposit and corrosion inhibition, as a tracer in water treatments, a micronutrient in fertilizers/food, and medicinal supplements, pigment agents, and laboratory reagents, etc.

Disodium molybdate is stable under ordinary temperatures and pressures. Store at 4°C - 25°C.
In case of spillage collect with sawdust and/or sand.
Disodium molybdate is a crystalline powder.
Disodium molybdate loses its water of crystallization at 100 degrees Celsius.
Disodium molybdate is known to be less toxic than the other corresponding compounds of group 6B elements in the periodic table.
Disodium molybdate is used in the manufacturing of inorganic and organic pigments, as a corrosion inhibitor.

Disodium molybdate is a small, lustrous, crystalline plate.
Disodium molybdate has the melting point of 687 degrees Celsius and a density of 3.28 (18C).
Disodium molybdate is soluble in water and also noncombustible.
Disodium molybdate can be used for reagent in analytical chemistry, paint pigment, production of molybdated toners and lakes, metal finishing, brightening agent for zinc plating, corrosion inhibitor, catalyst in dye and pigment production, additive for fertilizers and feeds, and micronutrient.

Disodium Molybdate uses cover a wide range of fields, including manufacturing, metalwork, printing, and more.
But the impact Disodium molybdate can have on plants and animals has brought it into the forefront of use for the agriculture industry, to the tune of more than 1 million pounds of sodium molybdate fertilizer used per year.
The basic chemistry of a molybdate, such as sodium molybdate, contains the element molybdenum in its highest oxidation state, which in turn helps contribute to a high solubility of the chemical in water, a benefit in fertilizer application.
This characteristic, when combined with sodium molybdate’s use as a delivery vessel for essential micronutrients (such as molybdenum) in plants, serves as another key reason for the choice of sodium molybdate fertilizer over other types of fertilizers used in agriculture.

Disodium molybdate has seen a particularly strong uptick in usage among farmers of leguminous plants, such as alfalfa, peas, beans, lentils and peanuts.
Included in fertilizer, Disodium molybdate provides these plants with enhanced uptake of the essential nitrogen element, while also allowing for efficient fixing of atmospheric nitrogen found in the atmosphere by bacteria in the legumes.
These bacteria convert the nitrogen into ammonia to synthesize amino acids within the plant.
Overall, the use of sodium molybdate in the agricultural industry can be summarized in that it is one of the few chemicals that can provide essential micronutrients and help drive plant function in a form that is both efficient and effective.

Efficiency is shown not only by the relatively small amounts needed to make an impact on the treated plants, but also in the ability to administer the chemical in easily-absorbed water-based formats.
Disodium molybdate may be used as an electrolyte additive, for use in electrochemical capacitors.
Addition of Na2MO4 as an electrolyte additive may result in enhanced capacitance, corrosion prevention and stabilized performance.
Disodium molybdate may also be used as a catalyst during the manufacture of paints and dyes.



USAGE:

The agriculture industry uses 1 million pounds per year as a fertilizer.
In particular, Disodium molybdate's use has been suggested for treatment of whiptail in broccoli and cauliflower in molybdenum-deficient soils.
Disodium molybdate is used in industry for corrosion inhibition, as it is a non-oxidizing anodic inhibitor.
The addition of sodium molybdate significantly reduces the nitrite requirement of fluids inhibited with nitrite-amine, and improves the corrosion protection of carboxylate salt fluids.

In industrial water treatment applications where galvanic corrosion is a potential due to bimetallic construction, the application of sodium molybdate is preferred over sodium nitrite.
Disodium molybdate has the advantage in that the dosing of lower ppm's of molybdate allow for lower conductivity of the circulating water.
Disodium molybdate at levels of 50-100 ppm offer the same levels of corrosion inhibition as sodium nitrite at levels of 800+ ppm.
By utilizing lower concentrations of sodium molybdate, conductivity is kept at a minimum and thus galvanic corrosion potentials are decreased.



APPLICATION:

-Used in the manufacture of alkaloids, dyes, fertilizers, pigments, catalysts, flame retardants and no Metal inhibitor for nuisance cooling water systems.
-For galvanized polishing agent and chemical reagent.
-The agricultural industry uses up to £1 million of fertilizer per year.
-In particular, Disodium molybdate has been proposed to be used for processing broccoli and cauliflower seeds on molybdenum-deficient soils.
-However, care should be taken as sodium molybdate at a level of 0.3 ppm can cause copper deficiencies in animals, particularly cattle.
-Disodium molybdate is used in industry for corrosion prevention because it is a non-oxidizing anodic inhibitor.
-The addition of sodium molybdate significantly reduces the nitrite requirement of nitrite-amine inhibited fluids and improves the corrosion protection of carboxylate salt fluids.
-In industrial water treatment applications where galvanic corrosion is potential due to the bimetallic structure, sodium molybdate is preferred rather than sodium nitrite.
-Disodium molybdate has the advantage that lower ppm molybdate dosing has lower conductivity of circulating water.
-Disodium molybdate at 50-100ppm offers the same levels of corrosion inhibition as sodium nitrite at 800+ppm.
-By using lower concentrations of sodium molybdate, conductivity is kept to a minimum and thus galvanic corrosion potentials are reduced.



USES:

-for the preparation of molybdenum salts and dyes, pigments, catalysts, corrosion inhibitors, etc.
-used as a metal corrosion inhibitor, descaling agent, bleach accelerators as well as skin and hair protective agent
-reagents for the analysis, with in the determination of alkaloids, dyes and pharmaceutical industry for the manufacture of
-alkaloids, ink, fertilizers, molybdenum red pigment and light fastness pigment precipitation agent, catalyst, molybdenum salt, can also be used to make flame retardants and pollution-free type water system metal inhibitors, also used as a galvanizing, polishing agents and chemical reagents.
-molybdate inhibitor belongs to the anodic oxide film formed on the anode ferrous iron - high-speed rail - the sky molybdenum oxide passivation film corrosion inhibition.



AGRICULTURAL USES:

Disodium molybdate is an important molybdenum source, is applied along with other fertilizers or as a foliar spray (with 39% molybdenum).
Disodium molybdate is the sodium salt of molybdic acid.
Disodium molybdate oxide with sodium carbonate or hydroxide makes sodium molybdate.
Disodium molybdate is an essential component of the enzyme nitrate reductase which catalyzes the conversion of nitrate (NO3-) to nitrite (NO2-).

Disodium molybdate is also a component of the nitrogenase enzyme involved in nitrogen fixation by root nodule bacteria of leguminous crops.
Soaking seeds in sodium molybdate solution (made with slurry or dust) before sowing is an effective seed treatment.
Disodium molybdate, the most commonly used fertilizer supplying molybdenum, is used as foliar spray, or in mixed fertilizers.
Disodium molybdate is also used in seed treatment.



REACTION:

When reacted with sodium borohydride, molybdenum is reduced to lower valent molybdenum(IV) oxide:

Na2MoO4 + NaBH4 + 2H2O → NaBO2 + MoO2 + 2NaOH + 3H2

Disodium molybdate reacts with the acids of dithiophosphates:

Na2MoO4 + (R = Me, Et) (RO)2PS2H → [MoO2(S2P(OR)2)2]

which further reacts to form [MoO3(S2P(OR)2)4].



BIOLOGICAL ACTIVITY:

Disodium molybdate is an acid phosphatase inhibitor. the osteoclastic acid phosphatase isoenzyme, secreted by osteoclasts, is a member of a widely-distributed class of iron-containing proteins with acid phosphatase activity.
Elevated plasma isoenzyme levels are associated with increased bone turnover in metabolic disease.
By inhibiting this class of acid phosphatases, sodium molybdate is capable of abolishing bone resorption.



PROPERTIES:

-White rhombus crystal
-Slightly soluble in water
-insoluble in acetone



PROPERTIES:

Molecular Weight: 205.93 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 207.864601 g/mol
Monoisotopic Mass: 207.864601 g/mol
Topological Polar Surface Area: 80.3Ų
Heavy Atom Count: 7
Complexity: 62.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes



PHYSICAL AND CHEMICAL PROPERTIES:

-Density: 2.71 g/cm3 (22 °C) (for the dihydrate)
-Melting Point: 687 °C Elimination of water of crystallisation
-pH value: 9 - 10 (840 g/l, H₂O, 20 °C)
-Bulk density: 1000 - 1400 kg/m3
-Solubility: 840 g/l



TECHNICAL INFORMATION:

-Appearance: Crystalline powder and crystalline
-Physical State: Solid
-Solubility: Soluble in water (840 mg/ml at 20° C).
-pH: 7.0-10.5
-Storage: Store at room temperature
-Melting Point: 100° C
-Density: 2.37 g/cm3



SPECIFICATION:

-Assay (precipitative titration, calculated on dried substance): 98.0 - 103.0 %
-Identity: passes test
-Appearance of solution: passes test
-Chloride (Cl): ≤ 0.005 %
-Phosphate (PO₄): ≤ 0.02 %
-NH₄ (Ammonium): ≤ 0.001 %
-Heavy metals (as Pb): ≤ 0.001 %
-Loss on drying (140 °C):14.0 - 16.0 %



CHEMICAL PROPERTIES:

-Density: 2.71 g/cm3 (22 °C) (for the dihydrate)
-Melting Point: 687 °C Elimination of water of crystallisation
-pH value: 9 - 10 (840 g/l, H₂O, 20 °C)
-Bulk density: 1000 - 1400 kg/m3
-Solubility: 840 g/l



SAFETY:

Disodium molybdate is incompatible with alkali metals, most common metals and oxidizing agents.
Disodium molybdate will explode on contact with molten magnesium.
Disodium molybdate will violently react with interhalogens.
Disodium molybdate's reaction with hot sodium, potassium or lithium is incandescent.



CHEMICAL PROPERTIES:

-Linear Formula: Na2MoO4
-MDL Number: MFCD00003486
-EC No.: 231-551-7
-Pubchem CID: 61424
-IUPAC Name: disodium dioxido(dioxo)molybdenum
-SMILES: [Na+].[Na+].[O-][Mo]([O-])(=O)=O
-InchI Identifier: InChI=1S/Mo.2Na.4O/q;2*+12-1
-InchI Key: TVXXNOYZHKPKGW-UHFFFAOYSA-N



STORAGE:

Store in a closed, cool, dry and ventilated place, and do not mix with toxic chemicals for transportation and storage.



SYNONYM:

Disodium molybdate
disodium,(T-4)-Molybdate
disodiummolybdate
Molybdate (MoO42-), disodium, (T-4)-
Molybdate (MoO42-), disodium, (T-4)-
molybdic
Molybdic acid (H2MoO4), disodium salt
Molybdic acid, disodium salt
Disodium molybdate
7631-95-0
Disodium molybdate
Disodium molybdate(VI)
Molybdate disodium
sodium molybdenum oxide
Natriummolybdat
Molybdic acid, disodium salt
sodium molybdate (anhydrous)
disodium;dioxido(dioxo)molybdenum
Anhydric sodium molybdate
Disodium Molybdate, anhydrous
13466-16-5
948QAQ08I1
MFCD00003486
Disodium molybdenum oxide, anhydrous, Mo 46.2%
Natriummolybdat
Disodium molybdate
Disodium dimolybdate
CCRIS 5442
Na2MoO4
EINECS 231-551-7
NSC 77389
Disodium Molybdate Anhydrous
Molybdic acid (H2MoO4), disodium salt
Molybdic acid (H2MoO4) , disodium salt
UNII-948QAQ08I1
Molybdate (MoO42-), disodium, (T-4)-
Molybdenum (as sodium)
disodium tetraoxomolybdate
sodium molybdate (anh.)
Molybdate (MoO42-), disodium, (beta-4)-
Molybdic acid, sodium salt
EC 231-551-7
Disodium molybdate, >=98%
Ddisodium Molybdate Dihydrate
Disodium Molybdate, ACS Grade
sodium dioxido(dioxo)molybdenum
SODIUM MOLYBDATE
SODIUM MOLYBDATE
CHEBI:75215
SODIUM MOLYBDATE
SODIUM MOLYBDATE
SODIUM MOLYBDATE
Disodium molybdate, LR, >=99.5%
NSC-77389
AKOS015912969
DB14496
MOLYBDENUM (AS SODIUM)
Disodium Molybdate Crystals, Technical Grade
FT-0701280
Disodium Molybdate Dihydrate (Technical Grade)
Molybdate (MoO42-), sodium (1:2), (T-4)-
Q414518

DISODIUM MOLYBDATE
Disodium molybdate is a crystalline powder essential for the metabolism and development of plants and animals as a cofactor for enzymes.
Disodium molybdate is an inorganic sodium salt having molybdate as the counterion.
Disodium molybdate contains a molybdate.
Disodium molybdate, Na2MoO4, is useful as a source of molybdenum.


CAS Number: 7631-95-0
EC Number: 231-551-7
Formula: MoNa2O4


This white, crystalline salt, Disodium molybdate is often found as the dihydrate, Na2MoO4·2H2O.
Disodium molybdate is a useful source of molybdate, a Molybdenum compound.
Disodium molybdate is a very fine white granule free-flowing and highly hydroscopic.


Disodium molybdate is a reagent in analytical chemistry, paint pigment, production of molybdated toners and lakes, metal finishing, brightening agent for zinc plating, corrosion inhibitor, catalyst in dye and pigment production, additive for fertilizers and feeds, and micronutrient.
Disodium molybdate is a fine white powder used for corrosion inhibition because it is a non-oxidizing anodic inhibitor.
Disodium molybdate is an acid phosphatase inhibitor.


The osteoclastic acid phosphatase isoenzyme, secreted by osteoclasts, is a member of a widely-distributed class of iron-containing proteins with acid phosphatase activity.
Disodium molybdate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Disodium molybdate is soluble powder for correcting molybdenum deficiency in plants.
Disodium molybdate is a source of molybdenum.
Molybdenum's fundamental role in the human body is as a constituent of molybdoenzymes; some important molybdoenzymes are xanthine oxidase, sulphite oxidase and aldehyde oxidase.


These are involved in the metabolism of sulphur amino acids and purine.
By converting sulphite to sulphate, sulphite oxidase aids the metabolising of the sulphur amino acids methionine and cysteine, a process that is crucial to human health.
This also helps the body reduce the harmful effects of sulphites generally.


Molybdenum is also an essential component of flavin- and iron-containing enzymes.
Most diets will contain a plentiful supply of molybdenum, as it is common in nuts, vegetables and cereals, and is found in drinking water to varying levels.
Disodium molybdate is used by the plant to convert nitrate into the building blocks for proteins and is crucial for certain plant hormones.


Disodium molybdate is generally immediately available in most volumes.
Disodium molybdate is an odourless white, crystalline powder with the chemical formula Na2MoO4.
Disodium molybdate is a white, odourless, free flowing crystalline solid.
The molybdate encourages the creation of a protective oxide film on metal surfaces.


There are two main forms of Disodium molybdate.
Disodium molybdate, Dihydrate is a crystalline powder.
It loses its water of crystallization at 100 degrees Celsius.
It is known to be less toxic than the other corresponding compounds of group 6B elements in the periodic table.


Disodium molybdate is stable under ordinary temperatures and pressures.
Disodium molybdate is stored at 4°C - 25°C.
In case of spillage collect with sawdust and/or sand.
Disodium molybdate ensures complete and fast assimilation and solubility and it does not alter pH values if used in nutrient solutions.


Disodium molybdate, Anhydrous is a small, lustrous, crystalline plate.
Disodium molybdate has the melting point of 687 degrees Celsius and a density of 3.28 (18C).
Disodium molybdate is soluble in water and also noncombustible.


Disodium molybdate is a white crystalline powder.
Disodium molybdate is a white, odourless, free-flowing crystalline solid.
Disodium molybdate is a hydrate that is the dihydrate form of sodium molybdate.
Disodium molybdate is a hydrate, an inorganic sodium salt and a molybdate.


Disodium molybdate contains a sodium molybdate (anhydrous).
Sodium molybdate, Na2MoO4, is useful as a source of molybdenum.
This white, crystalline salt is often found as the dihydrate, Na2MoO4•2H2O.
The molybdate(VI) anion is tetrahedral.


Two sodium cations coordinate with every one anion.
Disodium molybdate is an essential ingredient which a plant requires.
Sodium molybdate, Na2MoO4, is useful as a source of molybdenum.
It is often found as the dihydrate, Na2MoO4•2H2O.


Disodium molybdate is a plant micronutrient.
Disodium molybdate is generally immediately available in most volumes.
Hydrate or anhydrous forms of Disodium molybdate may be purchased.


Disodium molybdate has high purity, submicron and nanopowder forms may be considered.
Disodium molybdate, also known as Molybdic Acid Disodium Salt, or simply SMX, is a very fine, white, free-flowing technical grade granule represented by the formula: Na₂MoO₄•2H₂O.



USES and APPLICATIONS of DISODIUM MOLYBDATE:
The agriculture industry uses 1 million pounds per year as a fertilizer.
In particular, Disodium molybdate'ss use has been suggested for treatment of whiptail in broccoli and cauliflower in molybdenum-deficient soils.
However, care must be taken because at a level of 0.3 ppm sodium molybdate can cause copper deficiencies in animals, particularly cattle.


Disodium molybdate is used in industry for corrosion inhibition, as it is a non-oxidizing anodic inhibitor.
The addition of Disodium molybdate significantly reduces the nitrite requirement of fluids inhibited with nitrite-amine, and improves the corrosion protection of carboxylate salt fluids.
In industrial water treatment applications where galvanic corrosion is a potential due to bimetallic construction, the application of sodium molybdate is preferred over sodium nitrite.


Disodium molybdate has the advantage in that the dosing of lower ppm's of molybdate allow for lower conductivity of the circulating water.
Disodium molybdate at levels of 50-100 ppm offer the same levels of corrosion inhibition as sodium nitrite at levels of 800+ ppm.
By utilizing lower concentrations of Disodium molybdate, conductivity is kept at a minimum and thus galvanic corrosion potentials are decreased.
Disodium molybdate has displayed the ability to stabilize both the androgen and progesterone receptor.


When applied to non-activated estrogen receptors the Sodium Molybdate reversibly inhibited receptor activation.
In the Rat Sodium molybdate dihydrate inactivated both the active and inactive form of the gluco corticoid receptor complex.
With the use of nitrites, molybdate salts have been shown to reduce the emission of hydrogen sulphide from swine manure.
Disodium molybdate is used as a component to supply Molybdenum to plants in a complete fertilizer mixture.


Sodium molybdate is used as a Oligo- element for the agricultural industry, as raw material for the metal surface treatment industry and for the pigments production.
Elevated plasma isoenzyme levels are associated with increased bone turnover in metabolic disease.
By inhibiting this class of acid phosphatases, sodium molybdate is capable of abolishing bone resorption.
In addition, sodium molybdate has been shown to stabilize the nonactivated glucocorticoid-receptor complex.


Disodium molybdate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Disodium molybdate is used in the following products: anti-freeze products, heat transfer fluids, fertilisers and water treatment chemicals.
Release to the environment of Disodium molybdate can occur from industrial use: formulation of mixtures and of substances in closed systems with minimal release.


Other release to the environment of Disodium molybdate is likely to occur from: outdoor use as reactive substance, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


Release to the environment of Disodium molybdate can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).
Other release to the environment of Disodium molybdate is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use.


Disodium molybdate can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery).
Disodium molybdate is used in the following products: anti-freeze products, heat transfer fluids, metal working fluids, water softeners, water treatment chemicals, fertilisers and pH regulators and water treatment products.


Disodium molybdate is used in the following areas: agriculture, forestry and fishing, formulation of mixtures and/or re-packaging, health services and scientific research and development.
Other release to the environment of Disodium molybdate is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Disodium molybdate is used in the following products: water treatment chemicals, anti-freeze products, metal working fluids, washing & cleaning products and biocides (e.g. disinfectants, pest control products).
Disodium molybdate has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Disodium molybdate can occur from industrial use: formulation of mixtures and processing aids at industrial sites.


Other release to the environment of Disodium molybdate is likely to occur from: outdoor use.
Disodium molybdate is used in the following products: pH regulators and water treatment products, metal working fluids, water treatment chemicals, anti-freeze products and heat transfer fluids.
Disodium molybdate has an industrial use resulting in manufacture of another substance (use of intermediates).


Disodium molybdate is used in the following areas: formulation of mixtures and/or re-packaging and mining.
Disodium molybdate is used for the manufacture of: chemicals, pulp, paper and paper products, plastic products and machinery and vehicles.
Release to the environment of Disodium molybdate can occur from industrial use: in processing aids at industrial sites, as processing aid, of substances in closed systems with minimal release, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and formulation of mixtures.


Release to the environment of Disodium molybdate can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.
Disodium molybdate helps convert nitrate to amino acids and proteins.


Disodium molybdate can be soil or foliar applied.
The agricultural industry uses up to £1 million of fertilizer per year.
In particular, Disodium molybdate has been proposed to be used for processing broccoli and cauliflower seeds on molybdenum-deficient soils.
However, care should be taken as Disodium molybdate at a level of 0.3 ppm can cause copper deficiencies in animals, particularly cattle.


Disodium molybdate is used in industry for corrosion prevention because it is a non-oxidizing anodic inhibitor.
The addition of Disodium molybdate significantly reduces the nitrite requirement of nitrite-amine-inhibited fluids and improves the corrosion protection of carboxylate salt fluids.
In industrial water treatment applications where galvanic corrosion is potential due to the bimetallic structure, Disodium molybdate is preferred rather than sodium nitrite.


Disodium molybdate has the advantage that lower ppm molybdate dosing has lower conductivity of circulating water.
Disodium molybdate at 50-100ppm offers the same levels of corrosion inhibition as sodium nitrite at 800+ppm.
By using lower concentrations of Disodium molybdate, conductivity is kept to a minimum and thus galvanic corrosion potentials are reduced.
Disodium molybdate can be used to add molybdenum to the plant.


Disodium molybdate is widely used in the water treatment industry as a corrosion inhibitor in water treatment products.
Disodium molybdate is also used in agriculture as a micronutrient for plants and used in the manufacturing process of pigments, lubricants and an additive for metal finishing.
Disodium molybdate is used as a corrosion inhibitor to protect metal surfaces, as it is a non-oxidizing anodic inhibitor.


Disodium molybdate is also used for cooling water systems, engine coolants, metalworking fluids, metal finishing, oil drilling muds and as a fertiliser nutrient.
In fertiliser systems, Disodium molybdate is an essential micronutrient though required by plants in very minute amounts.
Disodium molybdate supports the essential metabolism of nitrogen and the synthesis of protein.


Soil that has no molybdenum at all cannot support plant life!
Disodium molybdate is 100% water soluble, compatible in many mixed fertiliser nutrient formulations, easy to apply and importantly easy to clean with no sticky residues.
Disodium molybdate, Dihydrate is used in the manufacturing of inorganic and organic pigments, as a corrosion inhibitor, as a bath additive for finishing metals finishing, as a reagent for alkaloids, and as an essential micronutrient for plants and animals.


Disodium molybdate can be used for reagent in analytical chemistry, paint pigment, production of molybdated toners and lakes, metal finishing, brightening agent for zinc plating, corrosion inhibitor, catalyst in dye and pigment production, additive for fertilizers and feeds, and micronutrient.


Overall, the use of Disodium molybdate in the agricultural industry can be summarized in that it is one of the few chemicals that can provide essential micronutrients and help drive plant function in a form that is both efficient and effective.
Efficiency is shown not only by the relatively small amounts needed to make an impact on the treated plants but also by the ability to administer the chemical in easily-absorbed water-based formats.


Disodium molybdate can be used to add molybdenum to the plant.
The plant uses molybdenum (Mo) to convert nitrate into proteins which are essential for plant hormones.
You can easily recognise a shortage of Molybdenum (Mo) by looking at deformed or yellow young leafs.


With older leaves the shortage can be recognised by looking for yellow leafs.
Disodium molybdate uses cover a wide range of fields, including manufacturing, metalwork, printing, and more.
But the impact Disodium molybdate can have on plants and animals has brought it into the forefront of use for the agriculture industry, to the tune of more than 1 million pounds of Disodium molybdate fertilizer used per year.


The basic chemistry of a molybdate, such as sodium molybdate, contains the element molybdenum in its highest oxidation state, which in turn helps contribute to a high solubility of the chemical in water, a benefit in fertilizer application.
This characteristic, when combined with sodium molybdate’s use as a delivery vessel for essential micronutrients (such as molybdenum) in plants, serves as another key reason for the choice of Disodium molybdate fertilizer over other types of fertilizers used in agriculture.


Another touchpoint for this usage ties back to the hydroponic nutrient practice that is growing in popularity.
Hydroponics is an agricultural method in which plants are grown without soil.
Instead, they receive their essential micronutrients through a water solvent, a practice that has shown growth rates almost 50 percent faster than traditional soil-grown plants, in addition to a higher yield from hydroponic plants.


Disodium molybdate has seen a particularly strong uptick in usage among farmers of leguminous plants, such as alfalfa, peas, beans, lentils and peanuts.
The agriculture industry uses 1 million pounds per year as a fertilizer. In particular, Disodium molybdate's use has been suggested for treatment of whiptail in broccoli and cauliflower in molybdenum-deficient soils.


Included in fertilizer, Disodium molybdate provides these plants with enhanced uptake of the essential nitrogen element, while also allowing for efficient fixing of atmospheric nitrogen found in the atmosphere by bacteria in the legumes.
These bacteria convert the nitrogen into ammonia to synthesize amino acids within the plant.


Overall, the use of Disodium molybdate in the agricultural industry can be summarized in that it is one of the few chemicals that can provide essential micronutrients and help drive plant function in a form that is both efficient and effective.
Efficiency is shown not only by the relatively small amounts needed to make an impact on the treated plants, but also in the ability to administer Disodium molybdate in easily-absorbed water-based formats.


Disodium molybdate is used in industry for corrosion inhibition, as it is a non-oxidizing anodic inhibitor.
The addition of Disodium molybdate significantly reduces the nitrite requirement of fluids inhibited with nitrite-amine, and improves the corrosion protection of carboxylate salt fluids.
In industrial water treatment applications where galvanic corrosion is a potential due to bimetallic construction, the application of Disodium molybdate is preferred over sodium nitrite.


Disodium molybdate has the advantage in that the dosing of lower ppm's of molybdate allow for lower conductivity of the circulating water.
Disodium molybdate at levels of 50-100 ppm offer the same levels of corrosion inhibition that sodium nitrite at levels of 800+ offer.
The molybdate encourages the creation of a protective oxide film on metal surfaces.


Disodium molybdate is used as a corrosion inhibitor to protect metal surfaces, as it is a non-oxidizing anodic inhibitor.
Disodium molybdate is used for cooling water systems, engine coolants, metalworking fluids, metal finishing and oil drilling muds.
Disodium molybdate is used as a fertilizer


Sodium Molybdate, Dihydrate, Crystal, Reagent, ACS is a white crystalline solid that is used in agriculture as a fertilizer and in water treatment as well as in industry as a corrosion inhibitor.
The agriculture industry uses 1 million pounds per year as a fertilizer.
In particular, Disodium molybdate's use has been suggested for treatment of whiptail in broccoli and cauliflower in molybdenum-deficient soils.


Disodium molybdate is used in industry for corrosion inhibition, as it is a non-oxidizing anodic inhibitor.
The addition of Disodium molybdate significantly reduces the nitrite requirement of fluids inhibited with nitrite-amine, and improves the corrosion protection of carboxylate salt fluids.
Disodium molybdate is a non-oxidizing anodic inhibitor, used in metal finishing, as a brightening agent for zinc plating, as a corrosion inhibitor, an additive as trace element for fertilizers, in animal feed supplements, in production of molybdate inorganic and in organic toners and pigments.


Disodium molybdate is used in industry for corrosion inhibition, as it is a non-oxidizing anodic inhibitor.
The addition of Disodium molybdate significantly reduces the nitrite requirement of fluids inhibited with nitrite-amine, and improves the corrosion protection of carboxylate salt fluids.
In industrial water treatment applications where galvanic corrosion is a potential due to bimetallic construction, the application of Disodium molybdate is preferred over sodium nitrite.


Disodium molybdate has the advantage in that the dosing of lower ppm's of molybdate allow for lower conductivity of the circulating water.
Disodium molybdate at levels of 50-100 ppm offer the same levels of corrosion inhibition as sodium nitrite at levels of 800+ ppm.
By utilizing lower concentrations of Disodium molybdate, conductivity is kept at a minimum and thus galvanic corrosion potentials are decreased.


Disodium molybdate is a useful source of molybdate, a Molybdenum (sc-235881) compound.
Disodium molybdate has displayed the ability to stabilize both the androgen and progesterone receptor.
When applied to non-activated estrogen receptors the Disodium molybdate reversibly inhibited receptor activation.


In the Rat Disodium molybdate inactivated both the active and inactive form of the gluco corticoid receptor complex.
With the use of nitrites, molybdate salts have been shown to reduce the emission of hydrogen sulphide from swine manure.
Disodium molybdate is used as a corrosion inhibitor for open and closed cooling water systems, engine coolants, metalworking fluids, metal finishing, and oil drilling mud’s.


Disodium molybdate is also used as a micronutrient in agriculture.
Disodium molybdate is a raw material for making flame retardants and a metal corrosion inhibitor for pollution-free cooling water systems.
Disodium molybdate is source of molybdate, ability to stabilize and inhibit the activity of various receptors.


-Disodium molybdate Application:
*Reagents for the manufacture of alkaloids and other substances
*For dyes, molybdenum red pigments, catalysts, molybdenum salts and light-fast lake precipitants.
*Disodium molybdate is a raw material for making flame retardants and a metal corrosion inhibitor for pollution-free cooling water systems.
*Disodium molybdate is a necessary trace component for animals and plants.


-Recommended Use of Disodium molybdate:
Adhesives & Cements, Animal Feed, Antifreeze, Cooling Water, Corrosion Inhibitors, , Drilling Mud, Engine Coolants, Fertilizer, Metal Finishing, Metalworking Fluids, Micronutrient, Oil Field Service Chemicals, Pigment, Water Treatment, Zinc Plating


-Disodium molybdate as a corrosion inhibitor:
Disodium molybdate is an ideal environmentally responsible corrosion inhibitor for water and cooling systems.
Capable of working across a variety of temperatures and pH levels, Disodium molybdate experiences no loss of chemical properties or effectiveness in a variety of hot or cold environments.
When used, Disodium molybdate is capable of inhibiting the corrosion of ferrous, copper and aluminium metals in the cooling water of both open and closed cooling systems.


-Disodium molybdate in Agriculture:
Disodium molybdate offers a useful source of molybdenum which is an excellent soil micronutrient and essential for healthy plant growth making it a popular choice of fertiliser within the agricultural industry.
Disodium molybdate is suitable for foliar or fertigation applications, it is used in small amounts to supply molybdenum to crops and livestock.
Disodium molybdate is also added to cattle feed when treating copper deficiencies.



REACTIONS OF DISODIUM MOLYBDATE:
When reacted with sodium borohydride, molybdenum is reduced to lower valent molybdenum(IV) oxide:
Na2MoO4 + NaBH4 + 2H2O → NaBO2 + MoO2 + 2NaOH + 3H2
Disodium molybdate reacts with the acids of dithiophosphates:
Na2MoO4 + (R = Me, Et)
(RO)2PS2H → [MoO2(S2P(OR)2)2]
which further reacts to form [MoO3(S2P(OR)2)4].



HISTORY OF DISODIUM MOLYBDATE:
Disodium molybdate was first synthesized by the method of hydration.
A more convenient synthesis is done by dissolving MoO3 in sodium hydroxide at 50–70 °C and crystallizing the filtered product.
The anhydrous salt is prepared by heating to 100 °C.
MoO3 + 2NaOH + H2O → Na2MoO4·2H2O



WHY THE AGRICULTURE INDUSTRY USES DISODIUM MOLYBDATE:
Disodium molybdate uses cover a wide range of fields, including manufacturing, metalwork, printing, and more.
But the impact Disodium molybdate can have on plants and animals has brought it into the forefront of use for the agriculture industry, to the tune of more than 1 million pounds of Disodium molybdate fertilizer used per year.

The basic chemistry of a molybdate, such as Disodium molybdate, contains the element molybdenum in its highest oxidation state, which in turn helps contribute to a high solubility of the chemical in water, a benefit in fertilizer application.
This characteristic, when combined with Disodium molybdate’s use as a delivery vessel for essential micronutrients (such as molybdenum) in plants, serves as another key reason for the choice of Disodium molybdate fertilizer over other types of fertilizers used in agriculture.

Another touchpoint for this usage ties back to the hydroponic nutrient practice that is growing in popularity.
Hydroponics is an agricultural method in which plants are grown without soil.
Instead, they receive their essential micronutrients through a water solvent, a practice that has shown growth rates almost 50 percent faster than traditional soil-grown plants, in addition to a higher yield from hydroponic plants.

Disodium molybdate has seen a particularly strong uptick in usage among farmers of leguminous plants, such as alfalfa, peas, beans, lentils and peanuts.
Included in fertilizer, Disodium molybdate provides these plants with enhanced uptake of the essential nitrogen element, while also allowing for efficient fixing of atmospheric nitrogen found in the atmosphere by bacteria in the legumes.
These bacteria convert nitrogen into ammonia to synthesize amino acids within the plant.



PHYSICAL and CHEMICAL PROPERTIES of DISODIUM MOLYBDATE:
Molecular weight: 205.94
Physical state solid
Color: white
Odor: odorless
Melting point/freezing point:
Melting point/range: 100 °C
Initial boiling point and boiling range: Not applicable
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: 130 °C - Elimination of water of crystallization
pH: 9 - 10 at 840 g/l at 20 °C

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: Not applicable
Water solubility: 840 g/l at 20 °C
Partition coefficient: n-octanol/water: Not applicable
Vapor pressure: Not applicable
Density: 2,71 g/cm3 at 22 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Molecular Weight: 205.93
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 207.864601

Monoisotopic Mass: 207.864601
Topological Polar Surface Area: 80.3 Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 62.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Formula: Na2MoO4
Molecular mass: 205.9
Melting point: 687°C
Density: 3.78 g/cm³
Solubility in water, g/100ml at 100°C: 84

Chemical formula: Na2MoO4
Molar mass: 205.92 g/mol (anhydrous), 241.95 g/mol (dihydrate)
Appearance: White powder
Density: 3.78 g/cm3, solid
Melting point: 687 °C (1,269 °F; 960 K)
Solubility in water: 84 g/100 ml (100 °C)
Refractive index (nD): 1.714
Compound Formula: MoNa2O4
Molecular Weight: 205.92
Appearance: White powder
Melting Point: N/A
Boiling Point: N/A
Density: 3.78 g/cm3
Solubility in H2O: N/A
Exact Mass: 207.864606
Monoisotopic Mass: 207.864606



FIRST AID MEASURES of DISODIUM MOLYBDATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of DISODIUM MOLYBDATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of DISODIUM MOLYBDATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of DISODIUM MOLYBDATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of DISODIUM MOLYBDATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510):
Non Combustible Solids



STABILITY and REACTIVITY of DISODIUM MOLYBDATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
no information available
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Sodium molybdate
7631-95-0
Disodium molybdate
Sodium molybdate(VI)
Molybdate disodium
sodium molybdenum oxide
Natriummolybdat
Molybdic acid, disodium salt
sodium molybdate (anhydrous)
dioxido(dioxo)molybdenum
Anhydric sodium molybdate
Sodium Molybdate, anhydrous
13466-16-5
948QAQ08I1
MFCD00003486
Sodium molybdenum oxide, anhydrous, Mo 46.2%
Sodium dimolybdate
CCRIS 5442
Na2MoO4
EINECS 231-551-7
NSC 77389
Sodium Molybdate Anhydrous
Molybdic acid (H2MoO4), disodium salt
Molybdic acid (H2MoO4) , disodium salt
UNII-948QAQ08I1
Molybdate (MoO42-), disodium, (T-4)-
Molybdenum (as sodium)
disodium tetraoxomolybdate
sodium molybdate (anh.)
Molybdate (MoO42-), disodium, (beta-4)-
Molybdic acid, sodium salt
EC 231-551-7
Sodium molybdate, >=98%
Ddisodium Molybdate Dihydrate
Sodium Molybdate, ACS Grade
sodium dioxido(dioxo)molybdenum
Sodium Molybdate 35% Solution
Sodium Molybdate Solution 35%
Sodium molybdate, LR, >=99.5%
NSC-77389
AKOS015912969
DB14496
Sodium Molybdate Crystals, Technical Grade
FT-0701280
Sodium Molybdate Dihydrate (Technical Grade)
Molybdate (MoO42-), sodium (1:2), (T-4)-
Q414518
Sodium molybdate, anhydrous, powder, -100 mesh particle size, 99.9% trace metals basis
Disodium Moblydate
Disodium Molybdate Anhydrous
MOLY
Molybdic Acid Disodium Salt
Molybdic Acid Disodium Salt Anhydrous
Sodium Molybdate
Sodium Molybdate Anhydrous
Sodium molybdate
Disodium molybdate
Disodium tetraoxomolybdate
Sodium molybdate(VI)
Sodium orthomolybdate

DISODIUM NADH
N° CAS : 68479-64-1 / 79702-63-9 Nom INCI : DISODIUM OLEAMIDO MEA-SULFOSUCCINATE Nom chimique : Disodium (Z)-[2-[(1-oxooctadec-9-enyl)amino]ethyl] 2-sulphonatosuccinate N° EINECS/ELINCS : 270-864-3 Classification : MEA Ses fonctions (INCI) Agent nettoyant : Aide à garder une surface propre Sinergiste de mousse : Améliore la qualité de la mousse produite en augmentant une ou plusieurs des propriétés suivantes: volume, texture et / ou stabilité Hydrotrope : Augmente la solubilité d'une substance qui est peu soluble dans l'eau. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
DISODIUM OLEAMIDO MEA-SULFOSUCCINATE
SYNONYMS Sodium Phosphate Dibasic Dodecahydrate; Disodium hydrogenphosphate Dodecahydrate;CAS NO. 10039-32-4
DISODIUM PHOSPHATE
disodium phosphate 12 hydrate; Sodium Phosphate Dibasic Dodecahydrate; Disodium hydrogenphosphate Dodecahydrate; cas no: 10039-32-4
DISODIUM PHOSPHATE (DSP)
Disodium phosphate (DSP) is a white powder material, highly soluble in water, which gives alkaline solutions.
Disodium phosphate (DSP), also known as Disodium Hydrogen Phosphate Dihydrate, is a white, crystalline powder.
Disodium phosphate (DSP) is highly soluble in water and has a variety of applications due to its versatile properties.


CAS Number: 7558-79-4
10028-24-7 (dihydrate)
7782-85-6 (heptahydrate)
10039-32-4 (dodecahydrate)
EC Number: 231-448-7
E-number: E339(ii)
Chemical formula: Na2HPO4


Disodium phosphate (DSP), or sodium hydrogen phosphate, or sodium phosphate dibasic, is the inorganic compound with the formula Na2HPO4.
Disodium phosphate (DSP) is one of several sodium phosphates.
Disodium phosphate (DSP) is known in anhydrous form as well as forms with 2, 7, 8, and 12 hydrates.


All are water-soluble white powders; the anhydrous salt being hygroscopic.
Disodium phosphate (DSP) is an inorganic compound derived from naturally occurring minerals.
Disodium Phosphate (DSP), or Disodium Hydrogen Phosphate, or Dibasic Sodium Phosphate, is an inorganic compound with the formula Na2HPO4.


This is one of several sodium phosphates.
This salt is known not only in its anhydrous form, but also in its 2-, 7-, 8-, and 12-hydrate forms.
All water-soluble white powders.


The pH of disodium hydrogen phosphate in water is between 8.0 and 11.0, meaning it is moderately basic.
HPO42− + H2O ⇌ H2PO4− + OH−
Disodium phosphate (DSP) also helps preserve sausages and cooked meats and make soft drinks and cheese smooth.


Disodium phosphate (DSP) helps preserve bakery products and enriched farina and maintain the smoothness of ice cream and artificially sweetened jelly.
Disodium phosphate (DSP) also known as Di-sodium hydrogen phosphate is the inorganic compound.
Disodium phosphate (DSP) is also one of the several sodium phosphates in anhydrous form.


Disodium phosphate (DSP) is water soluble and the anhydrous salt is hygroscopic.
Disodium phosphate (DSP) is obtained when a solution of phosphoric acid is reacted with caustic soda, until the higher PH is obtained.
Disodium phosphate is Sodium salt derived from Phosphate.


Disodium phosphate (DSP)'s properties are powder.
Disodium phosphate (DSP) dissolves well in water.
Disodium phosphate (DSP), or disodium hydrogen phosphate, or sodium phosphate dibasic, is the inorganic compound with the formula Na2HPO4.


Disodium phosphate (DSP) is one of several sodium phosphates.
Disodium phosphate (DSP) is known in anhydrous form as well as forms with 2, 7, 8, and 12 hydrates.
All are water-soluble white powders; the anhydrous salt being hygroscopic.


Disodium Phosphate (DSP), Na2HPO4 12H2O, is a white or colorless, crystalline, free flowing solid that is efflorescent in air.
Disodium phosphate (DSP) is easily soluble in water but is insoluble in alcohol; its water solution is slightly alkaline.
Disodium phosphate (DSP) is a white hygrospic inorganic compound. Disodium phosphate (DSP) is one of the several sodium phosphates and is soluble in water.


The pH of Disodium phosphate (DSP) water solution is between 8.0 and 11.0, meaning it is moderately basic:
HPO42− + H2O ⇌ H2PO4− + OH−
Disodium phosphate (DSP) is also known as disodium hydrogen orthophosphate, sodium hydrogen phosphate or sodium phosphate dibasic.


Disodium phosphate (DSP) is commercially available in both the hydrated and anhydrous forms pH of disodium hydrogen phosphate water solution is between 8.0 and 11.0
Disodium phosphate (DSP) is a sodium salt of phosphoric acid.
Disodium phosphate (DSP) is a white powder that is highly hygroscopic and water soluble.



USES and APPLICATIONS of DISODIUM PHOSPHATE (DSP):
Disodium phosphate (DSP) is used in combination with trisodium phosphate for food and water softening treatments.
Disodium phosphate (DSP) is used in food to regulate pH. Its presence prevents coagulation during the preparation of condensed milk.
Disodium phosphate (DSP) is likewise used as an anti-caking additive in powdered products.


Disodium phosphate (DSP) is used in desserts and puddings.
Disodium phosphate (DSP) is used cream of wheat to speed up cooking time or jello instant pudding to thicken.
Disodium phosphate (DSP) delays the formation of calcium scale in water treatment.


Disodium phosphate (DSP) is also found in some detergents and cleaners.
Heating the solid Disodium phosphate (DSP) yields the useful compound tetrasodium pyrophosphate.
2 Na2HPO4 → Na4P2O7 + H2O


Disodium phosphate (DSP), or disodium hydrogen phosphate, or sodium phosphate dibasic, is the inorganic compound with the formula Na HPO.
Disodium phosphate (DSP) is one of several sodium phosphates.
Disodium phosphate (DSP) is known in anhydrous form as well as forms with 2, 7, 8, and 12 hydrates.


Application Industries of Disodium phosphate (DSP): Foods
Disodium phosphate (DSP) is used to adjust pH.
Disodium phosphate (DSP)'s presence prevents coagulation in the preparation of condensed milk.


Disodium phosphate (DSP) is used as an anti-caking additive in powdered products.
Disodium phosphate (DSP) is used in desserts and puddings, e.g.Cream of Wheat to quicken cook time, and Jell-O Instant pudding for thickening.
Disodium phosphate (DSP) is used as a ingredient is Making Tofu (Soya Paneer)


Disodium phosphate (DSP) is used water treatment, it retards calcium scale formation.
Disodium phosphate (DSP) is used versatility in Industrial Use
Food Industry: Disodium phosphate (DSP) is used as a food additive, especially in processed meats and canned foods, acting as a preservative and emulsifier.


Water Treatment: Disodium phosphate (DSP) is employed in water treatment formulations to control scale and corrosion in boilers and cooling systems.
Pharmaceuticals: Disodium phosphate (DSP) serves as an excipient in some pharmaceutical formulations.


Disodium phosphate (DSP) can be used to produce citric acid, water softener and fabric increased weight agent, fire retardant agent and used to glaze, flux, medicine, pigment, industrial water treatment agent, dyeing detergent agents, quality improvement agents, neutralizer, antibiotics culture agent and biological treatment agent.


Disodium phosphate (DSP) is used as fire retardant agent for fabric, wood, paper.
Disodium phosphate (DSP) is used as the weighting agent of the silk; also can be used as an analytical reagent.
In welding and brazing, Disodium phosphate (DSP) is used instead of using borax.


Disodium phosphate (DSP) is used Water softening agent, tanning, dye, weight increasing agent in textile industry, fire retardant agent of wood and paper, welding agent, laxative inedicine, inoculum of peniciline
and streptomycin, adjusting liquid of Phmeasurement, deironagent, paint and pigment, food industry, baking powder and electroforming as well as materials for making pyrophosporate and other phosphates.


Disodium phosphate (DSP) is also found in some detergents and cleaning agents.
Disodium phosphate (DSP) is a food additive that combines the minerals phosphate, or phosphorus, and sodium.
Phosphate salts are also sometimes used as medicine, and they are generally regarded as safe by the U.S. Food and Drug Administration.


People with certain health conditions requiring low phosphorus intakes, however, may want to minimize the amount of disodium phosphate they consume.
A wide variety of other foods can also contain Disodium phosphate (DSP), including breading or batters, breakfast cereal, candied fruit, butter, chewing gum, cocoa and chocolate products, fruit juice products, coffee, tea, cider, dairy products, candy, processed vegetables, pudding, pasta, alcoholic beverages, sausage casings, egg- or fat-based desserts, salt, salt substitutes, soups, tofu, sweeteners and water-based beverages.


Disodium phosphate (DSP) is used as water softener of boiler, flame retardant of fabrics, wood and paper, detergent in production, galvanization, etc.
Disodium phosphate (DSP) could be an acid regulator due to its weak alkaline.
Disodium phosphate (DSP) is used as an anticaking agent and moisture retention agent for its hygroscopic; as a quality improver for condensed milk.


Disodium phosphate (DSP) is used as a stabilizer for dairy products, meat and fish products; a component in mixed salt for curing, and etc.
Disodium phosphate (DSP) is used Agricultural Chemicals, Animal Nutrition & Feed, Anti-caking Agents, Food & Beverage, Food Additives, Detergents, Solvents.
Disodium phosphate (DSP) has many applications in the food industries, used as an emulsifying agent, buffer, rehydration agent and brine constituent.


Disodium phosphate (DSP) is a food additive.
Disodium phosphate (DSP) is an anticaking, a buffering agent and also a humectant.
Disodium phosphate (DSP) helps to retain moisture in seafood.


Disodium phosphate (DSP) is used in the food industry as emulsifying agent, buffer, and brine constituent.
Examples such as processed cheeses and dairy products.
In the industry aspect, Disodium phosphate (DSP) is used as metal surface treatment, binder in enamel production, water treatment and component of cleaners.


Disodium phosphate (DSP) is widely used as a sequestrant, emulsifier & buffer in foods
Disodium phosphate (DSP) is also used as a mordant in dying, for weighing silk and in tanning
Disodium phosphate (DSP) is widely used in manufacturing of enamels, ceramics, detergents and boiler compounds


Disodium phosphate (DSP) is used as fire proofing agent, in soldering & brazing instead of borax
Disodium phosphate (DSP) crystal is used along with sodium phosphates in treatment of food and water.
Disodium phosphate (DSP) is added to fluid milk during pasteurization or spray drying to inhibit protein denaturation during heat treatment and allows efficient protein dispersion upon rehydration.


Disodium phosphate (DSP) is used in conjunction with trisodium phosphate in foods and water softening treatment.
In foods, Disodium phosphate (DSP) is used to adjust pH. Its presence prevents coagulation in the preparation of condensed milk.
Similarly, Disodium phosphate (DSP) is used as an anti-caking additive in powdered products.


Disodium phosphate (DSP) is used in desserts and puddings, e.g. Cream of Wheat to quicken cook time, and Jell-O Instant Pudding for thickening.
In water treatment, Disodium phosphate (DSP) retards calcium scale formation.
Disodium phosphate (DSP) is also found in some detergents and cleaning agents.


Heating solid disodium phosphate gives the useful compound tetrasodium pyrophosphate:
2 Na2HPO4 → Na4P2O7 + H2O
Laxative: Monobasic and dibasic sodium phosphate are used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.


Disodium Phosphate (DSP) is used as a pH buffer, stabilizer, and emulsifier in processed cheese, condensed milk, instant pudding, and other food applications.
Disodium phosphate (DSP) is also used as a buffering agent in textile and water treatment applications.
Disodium phosphate (DSP) is therefore used commercially as an anti-caking additive in powdered products.


Disodium phosphate (DSP) is used in dyestuffs and metal treatment.
Disodium phosphate (DSP) is also used in conjunction with trisodium phosphate in many steam-boiler applications.
Disodium phosphate (DSP) supplies the inventory of free phosphates to retard calcium scale formation.


Disodium phosphate (DSP) is also used in Metal cleaning, as a Buffer in Textile Processing, In dyestuffs for faster dispersion, Important ingredient in fire proofing formulations, For purification of clays, For manufacture of opal glass.
Food grade Disodium phosphate (DSP) is used as a food additive and buffering agent.
Disodium phosphate (DSP) is most commonly used commercially as an anti-caking agent.


Disodium phosphate (DSP) is available in both hydrate and anhydrous forms.
Disodium phosphate (DSP) can be used in a wide range of applications.
Disodium phosphate (DSP) is used Animal Nutrition & Feed, Agricultural Chemicals, Anti-caking agent, Food & Beverage, Detergents, Solvents, and Pharmaceuticals.


-Uses of Disodium phosphate (DSP) in Food:
When used as a food additive, Disodium phosphate (DSP) plays a number of roles.
Disodium phosphate (DSP) can help regulate the acidity of food, thicken it, stabilize it and maintain it at the proper moisture level.
Disodium phosphate (DSP) also helps keep oil-based and water-based ingredients, which would otherwise separate, mixed together.


-Potential Food Sources of Disodium phosphate (DSP):
Fish and seafood sometimes contain disodium phosphate to help keep them moist.
Otherwise, they lose significant amounts of water during processing and storage.


-Other Uses:
Disodium phosphate has nonfood applications, too.
Disodium phosphate (DSP) can be used in water treatment and as a flame retardant.
In medicine, Disodium phosphate (DSP) may help lower high blood levels of calcium or increase low blood levels of phosphate.



DESCRIPTION OF DISODIUM PHOSPHATE (DSP):
• Disodium phosphate (DSP) is a white or colorless crystalline free flowing solid.
• Disodium phosphate (DSP) is easily soluble in water, but insoluble in alcohol.
• Disodium phosphate (DSP) is water solution is slightly alkaline.
• The solubility of Disodium phosphate (DSP) is 51.004% at 100°C.



PRODUCTION METHODS OF DISODIUM PHOSPHATE (DSP):
How Disodium Phosphate is Manufactured:
Disodium phosphate (DSP) is typically produced by reacting phosphoric acid with sodium hydroxide.
This results in the formation of Disodium Phosphate, which is then carefully processed and tested to meet industry standards.



PRODUCTION AND REACTION OF DISODIUM PHOSPHATE (DSP):
Disodium phosphate (DSP) can be generated by neutralization of phosphoric acid with sodium hydroxide:
H3PO4 + 2 NaOH → Na2HPO4 + 2 H2O

Industrially Disodium phosphate (DSP) is prepared in a two-step process by treating dicalcium phosphate with sodium bisulfate, which precipitates calcium sulfate:
CaHPO4 + NaHSO4 → NaH2PO4 + CaSO4
In the second step, the resulting solution of monosodium phosphate is partially neutralized:
NaH2PO4 + NaOH → Na2HPO4 + H2O



PHYSICAL and CHEMICAL PROPERTIES of DISODIUM PHOSPHATE (DSP):
Chemical formula: Na2HPO4
Molar mass: 141.96 g/mol (anhydrous)
177.99 g/mol (dihydrate)
268.07 g/mol (heptahydrate)
Appearance: White crystalline solid
Odor: odorless
Density: 1.7 g/cm3
Melting point: 250 °C (482 °F; 523 K) decomposes
Solubility in water: 7.7 g/100 ml (20 °C)
11.8 g/100 mL (25 °C, heptahydrate)
Solubility: insoluble in alcohol
log P: -5.8
Acidity (pKa): 2.15, 6.82, 12.35
Magnetic susceptibility (χ): −56.6·10−6 cm3/mol
Refractive index (nD): 1.35644..1.35717 at 20°C
Appearance Form: granules
Color: white
Odor: odorless
Odor Threshold: Not applicable

pH: 8,9 - 9,2 at 50 g/l at 25 °C
Melting point/freezing point:
Melting point/range: > 450 °C -
Initial boiling point and boiling range: No data available
Flash point: Not applicable
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: No data available
Water solubility: at 20 °C soluble
Partition coefficient: n-octanol/water: Not applicable for inorganic substances
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Dissociation constant 6,87 at 20,4 °C



FIRST AID MEASURES of DISODIUM PHOSPHATE (DSP):
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of DISODIUM PHOSPHATE (DSP):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of DISODIUM PHOSPHATE (DSP):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of DISODIUM PHOSPHATE (DSP):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of DISODIUM PHOSPHATE (DSP):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Hygroscopic.
Keep in a dry place.



STABILITY and REACTIVITY of DISODIUM PHOSPHATE (DSP):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
Disodium hydrogen phosphate
Disodium hydrogen orthophosphate
Disodium hydrogen phosphate
Sodium phosphate dibasic
disodium phosphate
dibasic sodium phosphate
Acetest



DISODIUM PHOSPHATE (DSP)

Disodium phosphate (DSP) is an inorganic salt with the chemical formula Na₂HPO₄.
Also known as sodium hydrogen phosphate, it exists in various forms, including hydrates and anhydrous.
Disodium phosphate (DSP) is commonly used in the food industry as a buffering agent and emulsifier.

CAS Number: 7558-79-4, 10039-32-4
EC Number: 231-448-7, 231-554-3

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APPLICATIONS


Disodium phosphate (DSP) is widely used in the food industry as a pH regulator and emulsifying agent.
In baking, it functions as a leavening agent, contributing to the rise of baked goods.
Disodium phosphate (DSP) is employed in dairy products to control acidity and improve texture, particularly in processed cheese.
As a buffering agent, disodium phosphate helps maintain stable pH levels in various food and beverage products.

Disodium phosphate (DSP) is utilized in the preparation of certain canned and processed meats to enhance flavor stability.
Disodium phosphate (DSP) finds applications in the pharmaceutical industry as an excipient in tablet formulations.
In water treatment processes, it acts as a sequestering agent to inhibit the formation of scale.

Disodium phosphate (DSP) is added to some cleaning agents and detergents to soften water and improve their effectiveness.
Disodium phosphate (DSP) is used in the textile industry as a flame retardant in some fabric treatments.
In agriculture, it may be applied as a nutrient source for plants and to adjust soil pH.

Some electrolyte solutions in medical settings contain disodium phosphate to help balance ions in the body.
Disodium phosphate (DSP) is utilized in the production of adhesives, contributing to their formulation.

Disodium phosphate (DSP) has applications in the cosmetics industry, particularly in emulsions and creams.
Disodium phosphate (DSP) is employed in the manufacturing of ceramics to enhance certain properties of the materials.

Disodium phosphate (DSP) plays a role in controlling the setting time of plaster in construction applications.
In the production of textiles, it may be used in dyeing processes as a buffering agent.
Some flame retardant formulations for materials such as plastics and polymers contain disodium phosphate.
Disodium phosphate (DSP) is employed in analytical chemistry as a reagent for various laboratory experiments.

Disodium phosphate (DSP) may be found in certain dental products and toothpaste formulations.
In the beverage industry, it is used in some soft drinks to adjust acidity and provide a tart taste.

Disodium phosphate (DSP) is utilized in the synthesis of certain chemicals and pharmaceutical intermediates.
Disodium phosphate (DSP) has applications in the paper and pulp industry to prevent scale formation in the production process.
In the manufacturing of fire extinguishing agents, disodium phosphate can be used to modify formulations.

Some metal cleaning solutions contain disodium phosphate to enhance their cleaning properties.
Disodium phosphate (DSP) has diverse applications across industries, contributing to various products and processes.

In the production of canned soups and broths, disodium phosphate helps maintain the desired consistency and prevents separation.
Disodium phosphate (DSP) is used in the preparation of certain sports drinks to replenish electrolytes lost during physical activity.
Disodium phosphate (DSP) can be found in some dental products like mouthwash for its buffering properties.

Disodium phosphate (DSP) is added to some frozen seafood products to enhance the texture and prevent crystallization.
Disodium phosphate (DSP) is employed in the preparation of certain cheeses to improve the melting properties.
In the brewing industry, Disodium phosphate (DSP) may be used to adjust pH levels during the mashing process in beer production.

Disodium phosphate (DSP) finds applications in the pharmaceutical field for its role in certain drug formulations.
Disodium phosphate (DSP) is utilized in the production of specialty chemicals, including those used in photography.
In the pet food industry, it may be added to certain formulations to enhance nutrient absorption.
Some metal finishing processes utilize disodium phosphate in formulations for surface treatment.

Disodium phosphate (DSP) is employed in the creation of some household cleaning products for its water softening abilities.
Disodium phosphate (DSP) may be included in the formulation of certain fertilizers to provide essential phosphorus to plants.
In the textile industry, disodium phosphate is used as a buffering agent in dyeing processes.

Disodium phosphate (DSP) finds applications in the formulation of certain dietary supplements.
Disodium phosphate (DSP) is used in the production of fire-retardant coatings for wood and fabrics.
In the printing industry, it may be included in ink formulations to control pH levels.

Disodium phosphate (DSP) is utilized in some cosmetics and personal care products as a pH adjuster.
Disodium phosphate (DSP) has applications in the stabilization of certain enzymes in biochemical processes.
In the production of processed meats, it may be added to improve water retention and texture.

Disodium phosphate (DSP) is utilized in the manufacturing of certain ceramics and glazes.
Disodium phosphate (DSP) plays a role in the preservation of certain pickled and canned vegetables.
In the petroleum industry, disodium phosphate may be used in drilling mud formulations for specific purposes.

Disodium phosphate (DSP) is found in certain electrolyte replacement solutions used in medical settings.
Disodium phosphate (DSP) may be used in certain analytical chemistry techniques as a reagent for phosphate determination.
Disodium phosphate (DSP) is employed in the formulation of some dietary food supplements for animals.

Disodium phosphate (DSP) is commonly used in the production of processed and cured meat products, such as sausages and hams, to enhance flavor and improve texture.
In the dairy industry, it is added to evaporated milk to stabilize proteins and prevent coagulation.
Disodium phosphate (DSP) finds applications in the manufacturing of certain dessert mixes to provide a smooth texture and control acidity.

Disodium phosphate (DSP) is used as an additive in certain pharmaceutical formulations, including tablets and capsules.
In the construction industry, it may be included in some cement formulations to improve workability.
Disodium phosphate (DSP) is employed in some toothpaste formulations for its role in controlling tartar and preventing dental decay.

Disodium phosphate (DSP) is utilized in the production of certain insecticides and pesticides for its buffering properties.
In the creation of certain ceramics and pottery, disodium phosphate may be used as a flux.

Disodium phosphate (DSP) is found in certain fire extinguishing agents, contributing to their effectiveness.
Disodium phosphate (DSP) is utilized in the formulation of certain hair care products to adjust pH levels.
Disodium phosphate (DSP) may be included in the manufacturing of certain plastics to modify their properties.

Disodium phosphate (DSP) is used in the preservation of certain canned seafood products to maintain quality.
In the textile industry, it finds applications as a flame retardant in certain fabric treatments.
Disodium phosphate (DSP) may be added to certain industrial wastewater treatment processes to control pH.
Disodium phosphate (DSP) is employed in the production of specialty papers and cardboard for its role in controlling pH.

In the creation of certain adhesive formulations, disodium phosphate may be used for its adhesive properties.
Disodium phosphate (DSP) is found in certain rust removers and metal cleaning solutions for its effectiveness in removing oxide layers.
Disodium phosphate (DSP) is used in the manufacturing of certain cosmetics, particularly in formulations like facial cleansers.
In the production of specialty inks, such as those used in printing, disodium phosphate may be included for its pH control capabilities.

Disodium phosphate (DSP) is utilized in the creation of certain dietary supplements for animals, providing essential nutrients.
Disodium phosphate (DSP) is employed in the formulation of certain lubricants for its role in reducing friction.
Disodium phosphate (DSP) may be included in the manufacturing of certain specialty glass products for its fluxing properties.

Disodium phosphate (DSP) is used in the preparation of certain pickles to maintain crispness and control acidity.
In the creation of some automotive antifreeze formulations, it may be added for its buffering properties.
Disodium phosphate (DSP) is utilized in certain metalworking processes as a corrosion inhibitor and pH regulator.



DESCRIPTION


Disodium phosphate (DSP) is an inorganic salt with the chemical formula Na₂HPO₄.
Also known as sodium hydrogen phosphate, it exists in various forms, including hydrates and anhydrous.
Disodium phosphate (DSP) is commonly used in the food industry as a buffering agent and emulsifier.

Disodium phosphate (DSP) plays a crucial role in regulating acidity and improving texture in processed foods.
Disodium phosphate (DSP) appears as a white, crystalline powder or granules, depending on its form.
In laboratory settings, disodium phosphate is employed in chemical reactions and as a pH buffer.

The anhydrous form is a dry, crystalline material, while the hydrates contain water molecules in their structures.
Disodium phosphate (DSP) is soluble in water, and its solutions are alkaline.
As a food additive, it contributes to the leavening of baked goods and helps control the pH of dairy products.

In the pharmaceutical industry, it may be used as an excipient in tablet formulations.
Disodium phosphate (DSP) is commonly found in cleaning agents and detergents due to its water softening properties.
Disodium phosphate (DSP) is recognized for its ability to sequester metal ions, improving the effectiveness of certain detergents.

Disodium phosphate (DSP) is stable under normal conditions but may decompose at high temperatures.
Disodium phosphate (DSP) has a molecular weight of approximately 141.96 grams/mol.
Disodium phosphate (DSP) may be found in various industries, including agriculture, water treatment, and textiles.

Disodium phosphate (DSP) is a sodium salt of phosphoric acid, containing two sodium cations and one phosphate anion.
Disodium phosphate (DSP) may contribute to the preservation of processed meats by controlling pH and enhancing flavor stability.
Disodium phosphate (DSP) is odorless and has a slightly saline taste.

Disodium phosphate (DSP) is used in some electrolyte solutions for medical purposes.
When handled, Disodium phosphate (DSP) is important to wear appropriate protective equipment, including gloves and eye protection.
The different hydrate forms, such as the dodecahydrate, contribute to the versatility of this compound.

Disodium phosphate (DSP) has applications in water treatment processes to inhibit scale formation.
In the cosmetics industry, it may be used in formulations for its buffering and emulsifying properties.
Disodium phosphate (DSP) has a role in controlling the setting time of plaster in construction materials.
The production of adhesives, ceramics, and flame retardants are additional applications of disodium phosphate.



PROPERTIES


Physical Properties:

Appearance: White crystalline powder or granules.
Odor: Odorless.
Taste: Slightly saline taste.
Solubility: Soluble in water.
Density: Varies depending on the form (anhydrous or hydrated).
Molecular Weight: Approximately 141.96 grams/mol (anhydrous form).


Chemical Properties:

Chemical Formula: Na₂HPO₄.
pH: Acts as a buffering agent, controlling pH in various applications.
Ionization: Disassociates into sodium ions (Na⁺) and hydrogen phosphate ions (HPO₄²⁻) in aqueous solutions.
Hydration States: Anhydrous form and various hydrates (e.g., dodecahydrate).


Thermal Properties:

Melting Point: Varies depending on the form (e.g., anhydrous disodium phosphate has a melting point around 250°C).



FIRST AID


Inhalation:

Move to Fresh Air:
If disodium phosphate dust or vapors are inhaled and respiratory irritation occurs, promptly move the affected person to an area with fresh air.

Seek Medical Attention:
If respiratory difficulties persist or if there are signs of respiratory distress, seek medical attention immediately.


Skin Contact:

Remove Contaminated Clothing:
If disodium phosphate comes into contact with the skin, promptly remove contaminated clothing.

Wash Skin:
Wash the affected skin area with plenty of water and mild soap for at least 15 minutes.

Seek Medical Attention:
If irritation, redness, or other adverse skin reactions occur, seek medical advice.


Eye Contact:

Flush Eyes:
In case of eye contact, immediately flush the eyes with gentle, flowing water for at least 15 minutes.
Ensure eyelids are held open during flushing.

Seek Medical Attention:
If irritation persists or if there are signs of eye injury, seek immediate medical attention.


Ingestion:

Do Not Induce Vomiting:
If disodium phosphate is ingested, do not induce vomiting unless instructed to do so by medical personnel.

Rinse Mouth:
Rinse the mouth with water if the person is conscious and able to swallow.

Seek Medical Attention:
Seek immediate medical attention, and provide the medical personnel with details about the ingested substance.


General First Aid Precautions:

Provide Comfort:
Keep the affected person calm and provide reassurance during first aid measures.

Protective Equipment:
If administering first aid, wear appropriate personal protective equipment, such as gloves and safety glasses.

Do Not Delay Medical Attention:
If there is any uncertainty about the severity of exposure or if symptoms persist, seek prompt medical attention.



HANDLING AND STORAGE


Handling Conditions:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves and safety glasses, when handling disodium phosphate to prevent skin contact and eye irritation.

Ventilation:
Use in well-ventilated areas to minimize exposure to dust or vapors, especially in industrial settings.

Avoid Contamination:
Prevent contamination of disodium phosphate by ensuring that equipment, containers, and tools are clean and free of foreign substances.

Temperature Considerations:
Be aware of temperature sensitivity, especially if working with anhydrous forms.
Follow recommended temperature ranges for handling.

Handling Procedures:
Follow safe handling procedures, including proper lifting techniques and the use of equipment to avoid spillage.

Avoiding Skin Contact:
Minimize skin contact with disodium phosphate.
If contact occurs, wash the affected area thoroughly with water and mild soap.

Use in accordance with Regulations:
Adhere to local regulations and guidelines for the safe handling and use of disodium phosphate.


Storage Conditions:

Temperature and Humidity:
Store disodium phosphate in a cool, dry place, away from direct sunlight and extreme temperatures.
Some forms, especially hydrates, may have specific storage temperature requirements.

Separation from Incompatible Substances:
Store disodium phosphate away from incompatible substances, including strong acids, bases, and certain metals.

Container Integrity:
Ensure that storage containers are in good condition, properly sealed, and labeled with relevant information, including product identity and hazards.

Avoiding Contamination:
Store disodium phosphate away from materials that may contaminate it.
Use dedicated storage areas for chemicals.

Segregation from Food and Pharmaceuticals:
Keep disodium phosphate away from areas where food, pharmaceuticals, or other sensitive products are stored.

Protection from Moisture:
For anhydrous forms, protect from moisture to prevent clumping and caking. Consider using moisture-resistant packaging.

Proper Handling of Bags and Drums:
Handle bags and drums of disodium phosphate carefully to avoid damage, spills, or punctures.

Labeling and Documentation:
Clearly label storage containers with product information, hazard warnings, and handling instructions.
Maintain up-to-date documentation, including safety data sheets (SDS) and emergency contact information.

Emergency Equipment:
Keep emergency equipment, such as spill response kits and eye wash stations, accessible in the storage area.

Regular Inspections:
Conduct regular inspections of storage areas to ensure compliance with safety and regulatory requirements.


DISODIUM PHOSPHATE 12 HYDRATE
Sodium Phosphate Dibasic; Dsodium phosphoric acid; Disodium hydrogenphosphate; Disodium Hydrogenphosphate; Sodium monohydrogen phosphate; Disodium Hydrogen Orthophosphate; Disodium Phosphate; Phosphoric acid, disodium salt; sodium monohydrogen phosphate (2:1:1); dibasic sodium phosphate; disodium monohydrogen phosphate; disodium orthophosphate; DSP; soda phosphate; sodium hydrogen phosphate; Disodium Monophosphate; Disodium Monohydrogen Orthophoshate; cas no:7558-79-4
DISODIUM PHOSPHATE ANHYDRATE
Disodium Phosphate Anhydrate What is Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)? Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is a food additive. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)’s “generally recognized as safe” (GRAS) by the U.S. Food and Drug Administration (FDA) Phosphates like Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) are derived from the element phosphorus. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)s are used to enhance food characteristics like nutritional value and cooking performance. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is used in packaged foods, including macaroni and pastas. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is also used in some cheeses as an emulsifier. You can also find it in meat products, canned sauces, Jell-O, evaporated milk, and some chocolate. Originally derived from animal bones and urine, phosphorus is now extracted from phosphate rock. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is purified and put through chemical reactions. Is Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) safe? When it comes to food additives, it’s completely normal to wonder about safety. The FDA’s stance isn’t completely reassuring for some people. The Environmental Working Group (EWG) says there is a “fair” amount of data available on this phosphate. The EWG says that the additive can be considered safe. It’s not considered to be an environmental toxin or potentially harmful to humans. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is not bioaccumulative (where it accumulates within your body over time). Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is also classified as a “low human health priority” under Canadian law. In 2012, a studyTrusted Source was published declaring phosphates in general to be hazardous. The researchers suggested that all foods containing phosphates should be labeled as dangerous to public health. According to their research, accumulating phosphates in the body can cause organ calcification in people with renal failure, and even in people without kidney problems. But the International Food Additives Council states that inorganic phosphates have a long history of safe use in food and that additional studies have proven their safety. That being said, foods containing Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) are often packaged and heavily processed, so they’re not the healthiest choices to begin with. How to avoid Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) If you’re leery of Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) despite assurances of its safety, you can simply keep it out of your diet. However, identifying it may be difficult. In most cases, all you need to do is check the ingredients list on food packaging to tell if an item contains Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) or not. However, phosphates are also used in the meat industry to prevent spoilage, and meat packages don’t typically mention this. Avoiding packaged and processed foods is one way around Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE). Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) will benefit your overall health as well. Purchasing locally produced meats is another way to avoid Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE). Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) (DSP), or sodium hydrogen phosphate, or sodium phosphate dibasic, is the inorganic compound with the formula Na2HPO4. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is one of several sodium phosphates. The salt is known in anhydrous form as well as forms with 2, 7, 8, and 12 hydrates. All are water-soluble white powders; the anhydrous salt being hygroscopic. The pH of disodium hydrogen phosphate water solution is between 8.0 and 11.0, meaning it is moderately basic: Production and reactions Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) can be generated by neutralization of phosphoric acid with sodium hydroxide: H3PO4 + 2 NaOH → HNa2PO4 + 2 H2O Industrially Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is prepared in a two-step process by treating dicalcium phosphate with sodium bisulfate, which precipitates calcium sulfate: CaHPO4 + NaHSO4 → NaH2PO4 + CaSO4 In the second step, the resulting solution of monosodium phosphate is partially neutralized: NaH2PO4 + NaOH → HNa2PO4 + H2O Uses of Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is used in conjunction with trisodium phosphate in foods and water softening treatment. In foods, it is used to adjust pH. Its presence prevents coagulation in the preparation of condensed milk. Similarly, Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is used as an anti-caking additive in powdered products. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is used in desserts and puddings, e.g. Cream of Wheat to quicken cook time, and Jell-O Instant Pudding for thickening. In water treatment, it retards calcium scale formation. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is also found in some detergents and cleaning agents. Heating solid Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) gives the useful compound tetrasodium pyrophosphate: 2 HNa2PO4 → Na4P2O7 + H2O Monobasic and dibasic sodium phosphate are used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy. HPO42− + H2O ⇌ H2PO4− + OH− Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is a white, hygroscopic, odourless powder. Hydrated forms available include the dihydrate: a white crystalline, odourless solid; the heptahydrate: white, odourless, efflorescent crystals or granular powder; and the dodecahydrate: white, efflorescent, odourless powder or crystals. Although the concn of phosphate is low in the extracellular fluid, the anion is progressively concn in the renal tubule and represents the most abundant buffer system in the distal tubule. At this site, the secretion of H+ by the tubular cell in exchange for Na+ in the tubular urine converts disodium hydrogen phosphate to Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE). In this manner, large amt of acid can be excreted without lowering the pH of the urine to a degree that would block H+ transport by a high concn gradient between the tubular cell and luminal fluid. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is present in plasma and other extracellular fluid, in cell membranes and intracellular fluid, as well as in collagen and bone tissues. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) in the extracellular fluid is primarily in inorganic form and plasma levels may vary somewhat with age. The ratio of disodium phosphate and monosodium phosphate in the extracellular fluid is 4 to 1 (80% to 20%) at the normal pH of 7.4. This buffer ratio varies with the pH, but owing to its relatively low concentration, it contributes little to the buffering capacity of the extracellular fluid. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE), present in large amounts in erythrocytes and other tissue cells, plays a significant intracellular role in the synthesis of high energy organic phosphates. It has been shown to be essential to maintain red cell glucose utilization, lactate production, and the concentration of both erythrocyte adenosine triphosphate (ATP) and 2,3 diphosphoglycerate (DPG), and must be deemed as important to other tissue cells. NIOSH (NOES Survey 1981-1983) has statistically estimated that 1,230,592 workers (912,048 of these were female) were potentially exposed to Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) in the US(1). The NOES Survey does not include farm workers. Occupational exposure to Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) may occur through inhalation and dermal contact with this compound at workplaces where Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is produced or used(SRC). A great example of a chemical used in food production is Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE). There are three main sodium phosphates used in food production: monosodium phosphate (NaH2PO4), Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) (Na2HPO4), and trisodium phosphate (Na3PO4). Though each form is useful in food processing, here we will focus on how Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) works in food production. What Is Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)? Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is made with a simple chemical reaction between phosphoric acid (H3PO4) and sodium hydroxide. Phosphoric acid is a mineral acid. It neutralizes with sodium hydroxide, which acts as an alkaline substance during the reaction. Sodium atoms replace two of the three hydrogen atoms in the phosphoric acid and Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is formed. When used according to the FDA’s good manufacturing practices, Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is generally recognized as safe. Though we often think of processed food as a byproduct of the mid-20th century, sodium phosphates have been used in food production for over a century. Phosphates were used in cheese production as early as 1895. Likewise, sodium phosphates have historically been used in processed cheese, evaporated milk, and other fluid milk products. pH Control In Packaged Foods Among the most common uses of Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is as a neutralizing agent. It acts as a buffering solution that helps control pH. Buffering solutions, a type of water-soluble solution known as aqueous solutions, are created by mixing a weak acid and its conjugate base. When a harsh acid or base is added to the solution, the pH of the solution as a whole is minimally affected. Many consumable liquids require diligent monitoring of pH to keep them in the right state. For instance, creamy milk can quickly become tangy cottage cheese by reducing the pH of the milk by adding an acid. Keeping the pH stable also contributes to food safety. Foods with a pH of 4.6 or lower do not provide a hospitable environment for bacteria like Clostridium botulinum to grow. Stabilizing Our Dairy Most people love cheese but making it would be difficult without Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE). It acts as an emulsifier that keeps fat and water from separating during the cheese-making process. This helps us get the richest and creamiest cheese possible. In evaporated milk, it helps keep the butterfat from separating in the can and prevents an unpleasant gel from forming. And if you are a fan of whipped cream, you can thank Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) for the pleasure of picking it up at your local grocery store. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is used as a processing agent in heavy whipping cream where it binds to the natural minerals in milk. It prevents the heavy cream from becoming unmanageable and coating the equipment during processing. Controlling Texture & Food Preservation Salt was the first preservative used to keep meat, seafood, pork, and poultry safe for consumption. Over time, food manufacturers have incorporated Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) as a means of food preservation. But the benefit of using Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) on meats does not stop at preservation. It can improve the meat’s tenderness and make it appear juicier. Americans are lucky enough to live in a world where rich foods are just a shopping trip away. And we have come to rely on these convenience foods. The world of chemistry allows food manufacturers to create safe, enjoyable products that make our lives easier. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is just one of the sodium phosphates used in the making of these packaged foods. But there are numerous other sodium phosphates used in and out of the food manufacturing industry. What is Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)? Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is the sodium salt derived from phosphate rock in the earth. What does it do? In mouthwash Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) acts as a buffering agent that helps maintain the pH or acidity of the product. When Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is combined with fluoride and phosphoric acid to form an acidulated phosphate fluoride solution as outlined in the FDA’s Anticaries monograph, that solution promotes remineralization and helps prevent enamel dissolution. How is Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) made? Our Model guides us to select ingredients which have been processed in a manner that supports our philosophy of human and environmental health. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is made by combining phosphoric acid, derived from phosphate rock, with soda ash. This material is then crystallized and purified for use in our products. What are the alternatives? For anticaries mouthwash products, with acidulated phosphate fluoride solution, Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) and phosphoric acid are required in conjunction with Sodium Fluoride per the Anticaries Drug Products for Over-the-Counter Human Use, Final Monograph.1 Tom’s offers both fluoride and fluoride free mouthwash options. Is Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) the right option for me? Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is Generally Recognized as Safe (GRAS) by the FDA to be used as a food substance for human consumption. Phosphates like Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) are derived from the element phosphorus. They’re used to enhance food characteristics like nutritional value and cooking performance. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is used in packaged foods, including macaroni and pastas. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)’s also used in some cheeses as an emulsifier. You can also find it in meat products, canned sauces, Jell-O, evaporated milk, and some chocolate. Originally derived from animal bones and urine, phosphorus is now extracted from phosphate rock. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)’s purified and put through chemical reactions. Is Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) safe? When it comes to food additives, it’s completely normal to wonder about safety. The FDA’s stance isn’t completely reassuring for some people. The Environmental Working Group (EWG) says there is a “fair” amount of data available on this phosphate. The EWG says that the additive can be considered safe. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)’s not considered to be an environmental toxin or potentially harmful to humans. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is not bioaccumulative (where it accumulates within your body over time). Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)’s also classified as a “low human health priority” under Canadian law. In 2012, a studyTrusted Source was published declaring phosphates in general to be hazardous. The researchers suggested that all foods containing phosphates should be labeled as dangerous to public health. According to their research, accumulating phosphates in the body can cause organ calcification in people with renal failure, and even in people without kidney problems. But the International Food Additives Council states that inorganic phosphates have a long history of safe use in food and that additional studies have proven their safety. That being said, foods containing Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) are often packaged and heavily processed, so they’re not the healthiest choices to begin with. How to avoid Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) If you’re leery of Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) despite assurances of its safety, you can simply keep it out of your diet. However, identifying it may be difficult. In most cases, all you need to do is check the ingredients list on food packaging to tell if an item contains Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) or not. However, phosphates are also used in the meat industry to prevent spoilage, and meat packages don’t typically mention this. Avoiding packaged and processed foods is one way around Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE). This will benefit your overall health as well. Purchasing locally produced meats is another way to avoid Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE). Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is use in many applications such as sequestrant, emulsifier and buffer in foods. As mordant in dyeing for weighting silk, in tanning. In manufacturing of enamels, ceramics, detergents; as fireproofing agent in soldering and brazing instead of borax; as reagent and buffer in analytical chemistry, cathartic, laxative. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE), ACS, 98.0-102.0% MDLMFCD00149180EINECS231-448-7 Chemical Properties of Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) Formula Na2HPO4•7H2O Formula Weight 268.07 (141.98anhy)Form Crystalline Melting point 48.1°-5H{2}O Density 1.7 Storage & Sensitivity Ambient temperatures.Solubility Soluble in water and insoluble in ethanol. Applications of Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) Sodium hydrogen phosphate is widely used in detergents and cleaning agents. Combined with trisodium phosphate, it is employed in the food industry to adjust the pH and in water treatment to prevent calcium scale formation. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is utilized as a saline laxative to clean the bowel before a colonoscopy. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) prevents the coagulation of condensed milk. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is also utilized as anti-caking additive in powdered products. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) enhances the cook time and used as thickening agent in desserts and puddings. Phosphates like Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) are derived from the element phosphorus. They’re used to enhance food characteristics like nutritional value and cooking performance. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is used in packaged foods, including macaroni and pastas. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)’s also used in some cheeses as an emulsifier. You can also find it in meat products, canned sauces, Jell-O, evaporated milk, and some chocolate. Originally derived from animal bones and urine, phosphorus is now extracted from phosphate rock. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE)’s purified and put through chemical reactions. In 2012, a studyTrusted Source was published declaring phosphates in general to be hazardous. The researchers suggested that all foods containing phosphates should be labeled as dangerous to public health. According to their research, accumulating phosphates in the body can cause organ calcification in people with renal failure, and even in people without kidney problems. But the International Food Additives Council states that inorganic phosphates have a long history of safe use in food and that additional studies have proven their safety. That being said, foods containing Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) are often packaged and heavily processed, so they’re not the healthiest choices to begin with. How to avoid Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) If you’re leery of Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) despite assurances of its safety, you can simply keep it out of your diet. However, identifying it may be difficult. In most cases, all you need to do is check the ingredients list on food packaging to tell if an item contains Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) or not. However, phosphates are also used in the meat industry to prevent spoilage, and meat packages don’t typically mention this. Avoiding packaged and processed foods is one way around Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE). This will benefit your overall health as well. Purchasing locally produced meats is another way to avoid Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE). Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement. Disodium phosphate anhydrate (disodyum fosfat anhidrat, DISODIUM PHOSPHATE ANHYDRATE) is use in many applications such as sequestrant, emulsifier and buffer in foods. As mordant in dyeing for weighting silk, in tanning. In manufacturing of enamels, ceramics, detergents; as fireproofing agent in soldering and brazing instead of borax; as reagent and buffer in analytical chemistry, cathartic, laxative.
DISODIUM PHOSPHATE ANHYDROUS

Disodium phosphate anhydrous is a white, crystalline powder.
Disodium phosphate anhydrous is highly soluble in water.
Disodium phosphate anhydrous has a chemical formula of Na2HPO4.
Disodium phosphate anhydrous is odorless.

CAS Number: 7558-79-4
EC Number: 231-448-7



APPLICATIONS


Disodium phosphate anhydrous is commonly used as a food additive in the food industry, serving as a pH regulator, emulsifier, and stabilizer in processed foods.
Disodium phosphate anhydrous finds application in water treatment processes to prevent scaling and corrosion in boilers, cooling towers, and water distribution systems.
Disodium phosphate anhydrous is used as an excipient in the pharmaceutical industry, assisting in the formulation of medications and oral solutions.

Disodium phosphate anhydrous is employed in the production of cosmetics and personal care products, including toothpaste, mouthwash, and skin creams.
Disodium phosphate anhydrous is utilized as a laboratory reagent for various chemical reactions, pH adjustments, and biological assays.
Disodium phosphate anhydrous is added to detergents and cleaning products to enhance their cleaning efficiency by softening water and removing mineral deposits.

Disodium phosphate anhydrous is used in metal cleaning solutions and surface treatment formulations to remove rust, scale, and contaminants from metal surfaces.
In the textile industry, Disodium phosphate anhydrous serves as a pH regulator and buffer in dyeing processes to control the acidity or alkalinity of the dye bath.
Disodium phosphate anhydrous is employed in boiler water treatment formulations to control pH levels, prevent scale formation, and inhibit corrosion in steam generating systems.
Disodium phosphate anhydrous is utilized in agriculture as a source of phosphorus in fertilizers and animal feed supplements.
Disodium phosphate anhydrous is incorporated into electroplating baths to maintain stable plating conditions and improve the quality of the plated metal.

Disodium phosphate anhydrous finds application in fire retardant formulations to enhance flame resistance and reduce the risk of ignition.
In the ceramic industry, it acts as a fluxing agent in glazes and enamels to improve their fusion and flow during firing.
Disodium phosphate anhydrous is used in the paper manufacturing process as a pH regulator and a pulp dispersant.
Disodium phosphate anhydrous is added to cleaning agents to help remove stains, grease, and grime from various surfaces.

Disodium phosphate anhydrous is employed in metal surface treatment solutions to remove rust, scale, and contaminants from metal surfaces prior to further processing.
Disodium phosphate anhydrous is used in cooling and chilling systems to control pH and prevent scale formation on heat exchange surfaces.
Disodium phosphate anhydrous serves as a pH regulator and dispersing agent in water-based paint formulations.
In the oil and gas industry, it finds application as a corrosion inhibitor and pH regulator in drilling fluids, well stimulation fluids, and production processes.
Disodium phosphate anhydrous is sometimes added to adhesive and sealant formulations to adjust pH levels and enhance stability.
Disodium phosphate anhydrous is used in metalworking fluids to control pH and inhibit corrosion during machining operations.
Disodium phosphate anhydrous serves as a standard solution in pH calibration procedures for laboratory instruments and pH meters.
Disodium phosphate anhydrous is employed in the manufacturing of ceramics, including tiles and pottery, to improve glaze flow and adhesion.

Disodium phosphate anhydrous is used in the formulation of concrete admixtures to enhance workability and reduce water demand.
Disodium phosphate anhydrous finds application in the production of specialty chemicals, including flame retardants, corrosion inhibitors, and pH adjusters.


Disodium phosphate anhydrous has a wide range of applications in various industries.
Here are some of its common uses:

Food Industry:
Disodium phosphate anhydrous is used as a food additive and a buffering agent in processed foods, including cheese, meat products, canned foods, and baked goods.
Disodium phosphate anhydrous helps enhance food texture, stabilize pH, and prevent microbial growth.

Water Treatment:
Disodium phosphate anhydrous is employed in water treatment processes to prevent scaling, control pH levels, and inhibit corrosion in boilers, cooling towers, and other water systems.

Pharmaceutical Industry:
Disodium phosphate anhydrous is used as an excipient in the formulation of pharmaceutical products, serving as a pH adjuster and a stabilizer in certain medications and oral solutions.

Cosmetics and Personal Care Products:
Disodium phosphate anhydrous can be found in various cosmetics and personal care products, including toothpaste, mouthwash, skin creams, and hair care products, where it functions as a pH adjuster and a stabilizer.

Laboratory Reagent:
Disodium phosphate anhydrous is used as a reagent and a buffer in laboratory settings for various chemical reactions, pH adjustments, and biological assays.

Detergent Industry:
Disodium phosphate anhydrous is utilized as a builder in laundry detergents and dishwashing detergents to enhance their cleaning efficiency by softening water and removing mineral deposits.

Metal Cleaning and Surface Treatment:
Disodium phosphate anhydrous is used in metal cleaning solutions and surface treatment formulations to remove rust, scale, and contaminants from metal surfaces.

Textile Industry:
Disodium phosphate anhydrous is employed as a pH regulator and a buffer in textile dyeing processes to control the acidity or alkalinity of the dye bath and improve color fastness.

Boiler Water Treatment:
Disodium phosphate anhydrous is utilized in boiler water treatment formulations to control pH levels, prevent scale formation, and inhibit corrosion in steam generating systems.

Agriculture:
Disodium phosphate anhydrous can be used as a source of phosphorus in some agricultural applications, including fertilizers and animal feed supplements.

Electroplating:
Disodium phosphate anhydrous is utilized in electroplating baths as a buffering agent and pH adjuster to maintain stable plating conditions and improve the quality of the plated metal.

Fire Retardants:
Disodium phosphate anhydrous is incorporated into fire retardant formulations to enhance their effectiveness by providing flame resistance and reducing the risk of ignition.

Ceramic Industry:
Disodium phosphate anhydrous is used as a fluxing agent in ceramic glazes and enamels to promote fusion and improve the flow of the glaze during firing.

Paper Industry:
Disodium phosphate anhydrous is employed in the paper manufacturing process as a pH regulator and a pulp dispersant, helping to control acidity and improve pulp dispersion.

Cleaning Products:
Disodium phosphate anhydrous can be found in cleaning agents, such as multipurpose cleaners and degreasers, where it helps to remove stubborn stains, grease, and grime.

Metal Surface Treatment:
Disodium phosphate anhydrous is used in metal surface treatment solutions to remove rust, scale, and contaminants from metal surfaces prior to painting, coating, or further processing.

Cooling and Chilling Systems:
Disodium phosphate anhydrous is added to cooling and chilling systems to control the pH and prevent the formation of scale and deposits on heat exchange surfaces.

Water-Based Paints:
Disodium phosphate anhydrous is used as a pH regulator and a dispersing agent in water-based paint formulations, aiding in pigment dispersion and stability.

Oil and Gas Industry:
Disodium phosphate anhydrous finds application in the oil and gas sector as a corrosion inhibitor and pH regulator in drilling fluids, well stimulation fluids, and production processes.

Adhesives and Sealants:
Disodium phosphate anhydrous is sometimes incorporated into adhesive and sealant formulations to adjust pH levels, improve stability, and enhance adhesion properties.

Metalworking Fluids:
Disodium phosphate anhydrous is used in metalworking fluids, such as cutting fluids and grinding coolants, to control pH and inhibit corrosion on metal surfaces during machining operations.

pH Calibration:
Disodium phosphate anhydrous is employed as a standard solution in pH calibration procedures for laboratory instruments and pH meters.


Disodium phosphate anhydrous is used in the production of ceramic glazes to improve the surface finish and increase the gloss of ceramic products.
Disodium phosphate anhydrous is employed in the formulation of metal polishes to remove tarnish and restore the shine of metal surfaces.
Disodium phosphate anhydrous is used in the production of leather goods to aid in the tanning process and enhance the softness and durability of leather.

Disodium phosphate anhydrous is added to drilling muds in the oil and gas industry to improve the lubricity and stability of the mud during drilling operations.
Disodium phosphate anhydrous finds application in the manufacturing of fiberglass and composites as a pH regulator and a surface treatment agent.
Disodium phosphate anhydrous is used in the production of specialty papers, such as photographic papers and blueprint papers, to control pH and enhance print quality.
Disodium phosphate anhydrous is employed as a buffering agent in the fermentation process for the production of various alcoholic beverages.

Disodium phosphate anhydrous is added to certain dental products, such as mouthwashes and toothpastes, to help prevent tooth decay and promote oral health.
Disodium phosphate anhydrous is used in the formulation of fire extinguishing agents to control pH and improve the effectiveness of the extinguishing process.
Disodium phosphate anhydrous finds application in the textile industry for the preparation of fabrics prior to dyeing, ensuring better dye penetration and color fastness.
Disodium phosphate anhydrous is added to certain dietary supplements and sports nutrition products as a source of phosphorus, supporting bone health and energy metabolism.
Disodium phosphate anhydrous is employed in the manufacturing of ceramic tiles to improve their strength, durability, and resistance to moisture.

Disodium phosphate anhydrous is used in the production of animal feeds to provide essential phosphorus for proper growth and development.
Disodium phosphate anhydrous is added to certain water-based adhesives and sealants to improve their performance and increase their adhesive strength.
Disodium phosphate anhydrous is used in the formulation of oral care products, such as mouthwashes and gargles, to help freshen breath and promote oral hygiene.
Disodium phosphate anhydrous finds application in the production of fireproof coatings and paints for enhanced fire protection.

Disodium phosphate anhydrous is employed as a pH regulator and a nutrient source in hydroponic and aquaponic systems for optimal plant growth.
Disodium phosphate anhydrous is used in the production of animal vaccines as a stabilizing agent to maintain the efficacy of the vaccine during storage.
Disodium phosphate anhydrous is added to certain detergents and cleaning products as a surfactant and emulsifying agent for improved cleaning performance.
Disodium phosphate anhydrous finds application in the formulation of metalworking lubricants and coolants to improve tool life and reduce friction during machining operations.
Disodium phosphate anhydrous is used in the production of ceramic capacitors and electronic components as a dielectric material.
Disodium phosphate anhydrous is employed in the manufacture of water-soluble polymers for various industrial applications, such as adhesives and coatings.

Disodium phosphate anhydrous is added to certain paint strippers and removers to enhance their effectiveness in removing paint and coatings from surfaces.
Disodium phosphate anhydrous finds application in the formulation of liquid detergents and dishwashing solutions as a chelating agent for improved cleaning of dishes and utensils.
Disodium phosphate anhydrous is used in the production of heat transfer fluids to prevent scale formation and maintain thermal efficiency in heat exchange systems.



DESCRIPTION


Disodium phosphate anhydrous is a white, crystalline powder.
Disodium phosphate anhydrous is highly soluble in water.
Disodium phosphate anhydrous has a chemical formula of Na2HPO4.

Disodium phosphate anhydrous is odorless.
Disodium phosphate anhydrous has a slightly alkaline taste.
The compound is non-flammable.
Disodium phosphate anhydrous is stable under normal conditions.

Disodium phosphate anhydrous is hygroscopic, meaning it can absorb moisture from the air.
Disodium phosphate anhydrous is commonly used as a food additive and pH regulator.
The compound is widely employed in water treatment processes.
Disodium phosphate anhydrous is a source of phosphorus in various applications.

Disodium phosphate anhydrous has a molecular weight of approximately 141.96 g/mol.
Disodium phosphate anhydrous has a melting point of around 250°C (482°F).

Disodium phosphate anhydrous is an inorganic salt.
Disodium phosphate anhydrous can exist in different crystal forms, such as monoclinic or triclinic.

Disodium phosphate anhydrous is a versatile compound with multiple industrial uses.
Disodium phosphate anhydrous has the ability to form complexes with metal ions.
The compound is an effective buffering agent.

Disodium phosphate anhydrous can help control pH levels in a variety of applications.
Disodium phosphate anhydrous is considered safe for consumption when used in accordance with regulations.
Disodium phosphate anhydrous is used in the formulation of certain pharmaceutical products.
Disodium phosphate anhydrous is known for its ability to inhibit corrosion in water systems.

Disodium phosphate anhydrous is compatible with other chemicals and ingredients.
Disodium phosphate anhydrous is commonly found in cleaning products and detergents.
Disodium phosphate anhydrous is commercially available in various grades and concentrations.


Disodium phosphate anhydrous, also known as disodium hydrogen phosphate, is a chemical compound with the formula Na2HPO4.
Disodium phosphate anhydrous is the anhydrous form of disodium phosphate, which means it does not contain any water molecules in its crystal structure.
Disodium phosphate anhydrous is a white, crystalline powder that is highly soluble in water.

The chemical formula of disodium phosphate anhydrous indicates that it consists of two sodium ions (Na+) and one phosphate ion (HPO42-).
Disodium phosphate anhydrous is derived from phosphoric acid and sodium hydroxide.
Disodium phosphate anhydrous is commonly used as a food additive, buffering agent, and pH adjuster in various industries.



PROPERTIES


Chemical Formula: Na2HPO4
Molecular Weight: 141.96 g/mol
Appearance: White, crystalline powder
Odor: Odorless
Solubility: Soluble in water
Density: 1.52 g/cm3
Melting Point: 250 °C (482 °F)
Boiling Point: Decomposes at higher temperatures
pH (1% solution): Approximately 9.0-9.6
Water Content: Less than 1% (when anhydrous)
Hygroscopicity: Absorbs moisture from the air
Crystal Structure: Monoclinic or triclinic
Stability: Stable under normal conditions



FIRST AID


Inhalation:

Move the affected person to an area with fresh air.
If breathing is difficult, provide oxygen and seek medical attention.
If the person is not breathing, administer artificial respiration and seek immediate medical assistance.


Skin Contact:

Remove contaminated clothing and footwear.
Wash the affected area with plenty of soap and water for at least 15 minutes.
If irritation or redness develops, seek medical advice.
Wash contaminated clothing before reuse.


Eye Contact:

Rinse the eyes gently with water for at least 15 minutes, holding the eyelids open.
Seek immediate medical attention, even if the person's vision seems unaffected.
Remove contact lenses, if present and easily removable.


Ingestion:

Rinse the mouth thoroughly with water and give the affected person a glass of water to drink.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek immediate medical attention.
If large quantities have been ingested or if the person is unconscious, do not give anything by mouth and seek medical assistance.



HANDLING AND STORAGE


Handling:

Personal Protection:

Wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat or protective clothing.
Avoid skin and eye contact with the compound.
In case of accidental contact, follow the first aid measures mentioned earlier.

Ventilation:

Ensure good ventilation in the working area to prevent the accumulation of dust or vapors.
Use local exhaust ventilation or other engineering controls if necessary.

Spill and Leak:

In the event of a spill, contain the substance and prevent it from spreading.
Use appropriate absorbent materials to clean up the spill, avoiding the generation of dust.
Dispose of the spilled material according to applicable regulations.

Avoid Mixing:

Do not mix Disodium phosphate anhydrous with incompatible substances, such as strong acids or oxidizing agents, as it may cause hazardous reactions.
Follow proper handling procedures when working with other chemicals.

Handling Precautions:

Handle the compound with care to avoid generating dust, as inhalation of dust particles may cause respiratory irritation.
Avoid ingestion or direct contact with skin or eyes.
Wash hands thoroughly with soap and water after handling.


Storage:

Storage Conditions:

Store Disodium phosphate anhydrous in a cool, dry, well-ventilated area.
Keep the containers tightly closed and properly labeled.
Store away from sources of heat, ignition, and incompatible substances.

Segregation:

Store the compound away from acids, oxidizing agents, and strong bases to prevent the risk of reactions.
Segregate from other chemicals to avoid contamination.

Packaging:

Use suitable packaging materials, such as sealed containers or bags, to ensure the integrity of the product during storage.
Follow any specific storage requirements provided by the manufacturer or supplier.

Handling Precautions:

Follow good industrial hygiene practices, including regular cleaning of the storage area and proper maintenance of equipment.
Keep the storage area clearly labeled and separate from food, beverages, and animal feed.

Storage Stability:

Disodium phosphate anhydrous has good storage stability under normal conditions.
However, it is advisable to monitor the product for any signs of degradation, clumping, or changes in appearance.
Check the expiration date or recommended shelf life provided by the manufacturer and use the product accordingly.



SYNONYMS


Sodium hydrogen phosphate
Sodium phosphate dibasic
Disodium hydrogen phosphate
Sodium phosphate, dibasic
Sodium phosphate, anhydrous
Disodium orthophosphate
Dibasic sodium phosphate
Sodium monohydrogen phosphate
DSPA
Dibasic sodium phosphate, anhydrous
Disodium hydrogen phosphate, anhydrous
Disodium hydrogen phosphate dihydrate (synonym for hydrated form)
Sodium phosphate, Na2HPO4
Sodium phosphate, dibasic, anhydrous
Disodium hydrogen phosphate, anhydrous
Disodium hydrogen phosphate dihydrate
Sodium orthophosphate
Sodium phosphate (Na2HPO4)
Secondary sodium phosphate
Sodium phosphate, hydrate
Sodium phosphate, dibasic, dihydrate
Sodium phosphate, dihydrate
Sodium acid phosphate
Sodium phosphate, secondary
Sodium phosphate, dodecahydrate (synonym for hydrated form)
Sodium phosphate, dibasic, dihydrate
Disodium phosphate dihydrate
Disodium phosphate, dihydrate
Sodium hydrogen phosphate dihydrate
Sodium phosphate, secondary, dodecahydrate
Sodium phosphate, dodecahydrate
Disodium hydrogen phosphate, dihydrate
Sodium phosphate, dibasic, dodecahydrate
Sodium phosphate, dodecahydrate, dihydrate
Disodium hydrogen phosphate dodecahydrate
Sodium hydrogen phosphate dodecahydrate
Sodium phosphate, secondary, dihydrate
Sodium phosphate, dibasic, hydrate
Sodium phosphate, hydrate, dihydrate
Disodium phosphate hydrate
Disodium phosphate, dodecahydrate
Sodium hydrogen phosphate hydrate
Sodium phosphate, dibasic, dodecahydrate, dihydrate
Sodium phosphate, dodecahydrate, hydrate
Disodium hydrogen phosphate, dodecahydrate
Sodium hydrogen phosphate dodecahydrate, dihydrate
Sodium phosphate, secondary, hydrate
Sodium phosphate, dibasic, anhydrous, hydrate
Sodium phosphate, hydrate, dodecahydrate
Disodium phosphate, anhydrous, hydrate
DISODIUM PHOSPHATE ANHYDROUS


Disodium phosphate anhydrous, also known by its chemical formula Na2HPO4, is a salt of sodium and phosphate.
Disodium phosphate anhydrous is one of the inorganic compounds derived from phosphoric acid and is the anhydrous (water-free) form of disodium phosphate.
Disodium phosphate anhydrous consists of two sodium ions (Na+) and one phosphate ion (HPO4^2-) for every molecule.
Disodium phosphate anhydrous is a white, crystalline powder that is highly soluble in water.

CAS Number: 7558-79-4
EC Number: 231-448-7



APPLICATIONS


Disodium phosphate anhydrous is commonly used as a food additive to control the acidity and improve the texture of processed foods.
In the food industry, it functions as a buffering agent, helping to maintain the pH of various food products.
Disodium phosphate anhydrous is often found in processed cheeses, where it enhances the melting properties and texture, contributing to the creaminess of cheese sauces and spreads.
Disodium phosphate anhydrous plays a crucial role in baking, as it acts as a leavening agent in some baked goods, helping them rise and become light and fluffy.

In the dairy industry, it is utilized in the production of evaporated milk and condensed milk to stabilize the product and maintain its consistency.
Disodium phosphate anhydrous is used in the manufacturing of breakfast cereals to fortify them with essential minerals like phosphorus and sodium.

In the meat and seafood industry, it serves as a sequestrant, helping to improve the water-holding capacity of processed meats and prevent undesirable texture changes during cooking.
Disodium phosphate anhydrous is employed in some beverages, such as powdered drink mixes, as a pH regulator and to enhance the solubility of certain ingredients.
Disodium phosphate anhydrous is used in the preparation of canned soups and broths to maintain their flavor and quality during storage.

In the pharmaceutical industry, it is included in the formulation of certain medications to serve as a buffering agent, helping to stabilize the pH of the medication.
Disodium phosphate anhydrous is used in the preparation of oral rehydration solutions to help restore electrolyte balance in cases of dehydration.
Disodium phosphate anhydrous is a common ingredient in certain electrolyte beverages used to rehydrate after physical activity or illness.

In the cosmetic industry, it is utilized in skincare products to adjust the pH of formulations, ensuring they are gentle on the skin.
In the agricultural sector, it can be used in some plant fertilizers to provide essential nutrients to crops.

Disodium phosphate anhydrous is a water-softening agent in water treatment processes, helping to reduce the levels of hardness-causing ions in water.
Disodium phosphate anhydrous is found in some household cleaning products, particularly those used for dishwashing and dishwasher detergents.

In industrial applications, this compound is used as a corrosion inhibitor to protect equipment and pipes from rust and corrosion.
Disodium phosphate anhydrous is employed in some laboratory experiments and research as a buffering agent to control and maintain a constant pH level.

Disodium phosphate anhydrous is sometimes used in the production of fire-retardant coatings for wood and textiles.
Disodium phosphate anhydrous is utilized in the creation of emulsions and gels, enhancing their stability and shelf life.

In the brewing industry, it can be added to certain beer styles to adjust the pH of the brewing water and affect the beer's flavor profile.
Disodium phosphate anhydrous is used in the manufacture of detergents and cleaning agents, contributing to their cleaning efficiency.
In the textile industry, it is used as a sizing agent to improve the quality and durability of fabrics.

Disodium phosphate anhydrous is a versatile compound with applications in the development of ceramics, especially in the glazing and clay body formulation.
Disodium phosphate anhydrous is employed in certain analytical chemistry procedures and experiments to help maintain the desired pH conditions for accurate measurements.

Disodium phosphate anhydrous is used in the dairy industry to control the pH of dairy products such as yogurt, ensuring they maintain their desired texture and flavor.
Disodium phosphate anhydrous is a common ingredient in powdered desserts and dessert mixes, contributing to their smooth consistency and preventing separation.
In the pet food industry, this compound is used to adjust the pH of pet food formulations and maintain product stability.

Disodium phosphate anhydrous is added to certain toothpaste formulations as a pH adjuster and stabilizer to ensure product efficacy.
Disodium phosphate anhydrous plays a role in the production of synthetic detergents and cleaning products, enhancing their cleaning power.

In the production of non-alcoholic beverages, it can be used as an emulsifier and stabilizer to improve product quality.
Disodium phosphate anhydrous is found in some dietary supplements and nutritional products, providing a source of essential minerals.
Disodium phosphate anhydrous is used in the pulp and paper industry to adjust the pH of paper pulps during the papermaking process.
In the construction industry, it is employed in cement formulations as a retardant to control the setting time of cement-based products.

Disodium phosphate anhydrous is utilized in the creation of adhesives to improve their bonding properties and consistency.
Disodium phosphate anhydrous is added to some frozen desserts to maintain their texture and prevent crystallization.

In the textile industry, it can be used as a dye-leveling agent to ensure uniform color distribution in fabrics.
Disodium phosphate anhydrous is found in certain hair care products, helping to adjust the pH of shampoos and conditioners.
In the petroleum industry, it is used as a drilling mud additive to improve the stability and viscosity of drilling fluids.

Disodium phosphate anhydrous is included in some fire extinguishing agents to enhance their fire-suppressing properties.
Disodium phosphate anhydrous is employed in the production of synthetic resins, contributing to their adhesive properties and consistency.

In the formulation of some pharmaceutical tablets, it acts as a disintegrant, aiding in the breakdown of the tablet for effective drug release.
Disodium phosphate anhydrous is used in the manufacturing of ceramic glazes and engobes, contributing to their texture and appearance.
Disodium phosphate anhydrous is a key ingredient in the creation of printing inks, enhancing their viscosity and printability.

In the agriculture industry, it can be used as a pH regulator in irrigation water to optimize soil pH for crop growth.
Disodium phosphate anhydrous is included in some fireproofing products to enhance their fire-resistant properties.
Disodium phosphate anhydrous is found in some heating and cooling systems as a corrosion inhibitor to protect equipment and pipes.

In the cosmetics industry, it is used in hair coloring products to maintain the stability of the product.
Disodium phosphate anhydrous is employed in certain explosives formulations, where it serves as a stabilizer.

In the manufacture of ceramic tiles, it can be used in glaze formulations to improve the adherence and appearance of the glaze.
Disodium phosphate anhydrous is a crucial component in the preparation of certain medical contrast agents used in diagnostic imaging procedures, enhancing their solubility and stability.
In the textile printing industry, it is used as a dye thickener to improve the consistency and control of color application.
Disodium phosphate anhydrous is added to powdered spices and seasonings to prevent caking and maintain their free-flowing nature.

In the manufacture of drilling and fracking fluids in the oil and gas industry, it helps control the viscosity of these fluids for efficient well drilling and completion.
Disodium phosphate anhydrous is utilized in the production of certain ceramics, particularly in the formulation of engobes, which are used for decorative coatings on ceramic products.
Disodium phosphate anhydrous is incorporated into the creation of certain abrasive cleaners to enhance their scrubbing efficiency.

In the brewing and beverage industry, it is used in water treatment to adjust the pH of brewing water and influence the flavor and quality of the final product.
Disodium phosphate anhydrous can be employed in cooling water treatment to prevent scale and corrosion in cooling systems.
Disodium phosphate anhydrous is utilized in the formulation of some dishwashing detergents to improve their cleaning and grease-cutting properties.

In the manufacture of plasterboard, it is used as a setting regulator to control the setting time of the plaster.
Disodium phosphate anhydrous is added to some hair care products, contributing to the stability and pH balance of shampoos and conditioners.
Disodium phosphate anhydrous plays a role in the preservation of canned fruits and vegetables, helping to maintain their color, texture, and overall quality.

In the laboratory, it is used in the preparation of buffer solutions for various experiments and analytical procedures.
Disodium phosphate anhydrous is found in the production of certain antifreeze solutions, improving their performance in cold weather conditions.

In the manufacture of rubber products, it is used as a dispersing agent to evenly distribute rubber components.
Disodium phosphate anhydrous is included in some specialty welding fluxes used in metalworking to protect welds from contamination and ensure high-quality joints.

Disodium phosphate anhydrous can be employed in the formulation of certain heat treatment baths used to harden metal parts.
In the leather tanning industry, it is used as an auxiliary agent in the tanning process, assisting in the penetration of tanning agents.
Disodium phosphate anhydrous is used as a pH regulator in the production of wastewater treatment chemicals to optimize treatment processes.

In the printing industry, it is utilized as a buffering agent in fountain solutions for offset printing, ensuring stable pH levels during printing.
Disodium phosphate anhydrous can be added to some automotive and industrial cleaning products, improving their performance in removing grease and grime.
Disodium phosphate anhydrous is used in some fireproofing materials to enhance their fire-resistant properties, providing protection in case of fire.

In the production of certain pesticides and herbicides, it serves as a pH regulator in the formulation process.
Disodium phosphate anhydrous can be utilized in the creation of certain insect baits, enhancing their attractiveness to target pests.
Disodium phosphate anhydrous is employed in the construction industry as a setting regulator in cement-based products to control the hardening time of mortars and concretes.
In the textile industry, it is used as a sizing agent to improve the quality and durability of fabrics, particularly in weaving and textile finishing.

Disodium phosphate anhydrous finds application in the formulation of ceramic glazes, where it contributes to glaze adherence, smoothness, and gloss.
Disodium phosphate anhydrous is used in certain oral care products, such as mouthwash, to adjust the pH of the product and enhance its effectiveness.

In the construction industry, this compound is included in the preparation of plaster to regulate the setting time, allowing for proper workability.
Disodium phosphate anhydrous serves as a corrosion inhibitor in cooling water systems, protecting equipment and pipelines from rust and scale.
Disodium phosphate anhydrous is used in the creation of adhesive products to enhance bonding properties and product consistency.

In the brewing industry, it is added to specific beer styles to adjust brewing water pH, affecting the beer's flavor and character.
Disodium phosphate anhydrous plays a role in the pulp and paper industry, where it is utilized as a pH regulator in paper pulps for papermaking.
Disodium phosphate anhydrous is incorporated into certain drilling fluids in the oil and gas industry, aiding in the control of fluid viscosity during drilling operations.
Disodium phosphate anhydrous is used as a sequestrant in the meat processing industry, helping to improve water retention in processed meats and prevent textural changes during cooking.

Disodium phosphate anhydrous is employed in the production of fire-extinguishing agents, enhancing their firefighting properties.
Disodium phosphate anhydrous can be found in certain fireproofing materials used in the construction industry to improve fire resistance.

In the cosmetics industry, it is used in hair color products to maintain the stability and pH balance of the product.
Disodium phosphate anhydrous plays a crucial role in the formulation of oral rehydration solutions, helping to restore electrolyte balance in cases of dehydration.

In the manufacture of synthetic detergents, it contributes to their cleaning efficiency and grease-cutting properties.
Disodium phosphate anhydrous is utilized in the preparation of powdered drink mixes and beverages to adjust pH levels and enhance solubility.
In the pharmaceutical industry, it is included in the formulation of tablets as a disintegrant to facilitate drug release upon ingestion.

Disodium phosphate anhydrous can be added to pet food to maintain pH levels and product stability.
Disodium phosphate anhydrous is used in the creation of synthetic resins, contributing to adhesive properties and product consistency.

In the agriculture sector, it can be employed to adjust the pH of irrigation water and optimize soil pH for crop growth.
Disodium phosphate anhydrous is a common ingredient in non-alcoholic beverages, contributing to product stability and flavor enhancement.
Disodium phosphate anhydrousis utilized in the production of synthetic rubber products to ensure uniform distribution of rubber components.
Disodium phosphate anhydrous is employed in the manufacture of ceramic tiles to improve glaze adherence and overall appearance.

In the automotive industry, it can be found in some specialty welding fluxes, protecting welds from contamination and ensuring high-quality joints.
Disodium phosphate anhydrous is used as a buffering agent in the formulation of dental products such as toothpaste to stabilize pH levels and improve product efficacy.



DESCRIPTION


Disodium phosphate anhydrous, also known by its chemical formula Na2HPO4, is a salt of sodium and phosphate.
Disodium phosphate anhydrous is one of the inorganic compounds derived from phosphoric acid and is the anhydrous (water-free) form of disodium phosphate.
Disodium phosphate anhydrous consists of two sodium ions (Na+) and one phosphate ion (HPO4^2-) for every molecule.
Disodium phosphate anhydrous is a white, crystalline powder that is highly soluble in water.

Disodium phosphate anhydrous is commonly used in various applications, including as a food additive (E339) to regulate acidity and improve food texture.
Disodium phosphate anhydrous is also employed in water treatment processes, as a buffering agent in chemistry, and in some pharmaceutical preparations.
Additionally, it has applications in the manufacture of detergents and cleaning products.

Disodium phosphate anhydrous is a white, crystalline powder with a fine texture.
Disodium phosphate anhydrous is highly soluble in water, forming clear and colorless solutions.
Disodium phosphate anhydrous is derived from phosphoric acid and contains two sodium ions (Na+) and one phosphate ion (HPO4^2-) in each molecule.

Disodium phosphate anhydrous is often used as a pH regulator in various applications.
Disodium phosphate anhydrous is sometimes referred to as disodium hydrogen phosphate.

In the food industry, it serves as a food additive with the E number E339, commonly used to adjust the acidity of processed foods.
Disodium phosphate anhydrous is odorless and has a slightly salty taste.

Disodium phosphate anhydrous is known for its water-softening properties and is used in water treatment processes.
Disodium phosphate anhydrous plays a crucial role in the production of processed cheese products, where it helps improve the texture and melting properties.
In pharmaceutical formulations, it can be used as a buffering agent to stabilize the pH of medications.

Disodium phosphate anhydrous is employed in the preparation of emulsions and gels, enhancing their stability.
Disodium phosphate anhydrous is a key ingredient in certain electrolyte solutions used for medical and hydration purposes.

In laboratory settings, it is used as a buffering agent in chemical reactions to maintain a constant pH level.
Disodium phosphate anhydrous is sometimes used in combination with other chemicals to create effective cleaning agents.
Disodium phosphate anhydrous can serve as a corrosion inhibitor in cooling water systems and industrial applications.

Disodium phosphate anhydrous is a hygroscopic compound, meaning it can absorb moisture from the air.
Disodium phosphate anhydrous has the chemical formula Na2HPO4 and is classified as a sodium salt of phosphoric acid.

In the agriculture industry, it is used as a nutrient source in some plant fertilizers.
Disodium phosphate anhydrous is non-flammable and does not pose significant fire hazards.
Disodium phosphate anhydrous is considered safe for consumption in the quantities typically used in food products.

Disodium phosphate anhydrous is used as a component in some oral care products, such as toothpaste and mouthwash.
Disodium phosphate anhydrous can be found in certain food items, including processed meats, baked goods, and canned soups.

In the cosmetic industry, Disodium phosphate anhydrous is sometimes used in skincare products to adjust pH levels.
Disodium phosphate anhydrous is available in various grades, each suited for specific applications.



PROPERTIES


Chemical Formula: Na2HPO4
Molecular Weight: 141.96 g/mol
Appearance: White, crystalline powder
Odor: Odorless
Taste: Slightly salty
Solubility: Highly soluble in water, forming clear and colorless solutions.
pH (1% solution): Alkaline, typically around 8.0 - 9.0
Density: 2.45 g/cm³
Melting Point: Approximately 250°C (482°F)
Boiling Point: Decomposes before reaching a boiling point.
Hygroscopicity: Exhibits hygroscopic properties, absorbing moisture from the air.
Water Softening: Used as a water-softening agent to reduce water hardness by binding to calcium and magnesium ions.
Ionization: Forms sodium ions (Na+) and phosphate ions (HPO4^2-) in solution.
Non-Flammable: Does not pose significant fire hazards.
Corrosion Inhibitor: Acts as a corrosion inhibitor in cooling water systems and industrial applications.
Buffering Agent: Used as a buffering agent to stabilize pH levels in various applications.
Dispersing Agent: Serves as a dispersing agent to evenly distribute components in rubber products.
Sequestrant: Functions as a sequestrant in the meat industry to improve water retention in processed meats.



FIRST AID


Inhalation:

If Disodium phosphate anhydrous dust or mist is inhaled, move the affected person to an area with fresh air.
Allow the person to rest in a comfortable position.
If breathing difficulties persist or if symptoms worsen, seek immediate medical attention.


Skin Contact:

In case of skin contact with Disodium phosphate anhydrous, immediately remove contaminated clothing and jewelry.
Wash the affected skin area thoroughly with plenty of water for at least 15 minutes.
Use mild soap to aid in cleaning, and ensure that the chemical is completely removed from the skin.
Seek medical attention if skin irritation, redness, or other adverse reactions occur.


Eye Contact:

If Disodium phosphate anhydrous comes into contact with the eyes, immediately flush the eyes with gently flowing lukewarm water for at least 15 minutes.
Keep the affected person's eyes open to ensure thorough rinsing.
Remove contact lenses, if applicable, after the initial flush.
Seek immediate medical attention, especially if eye irritation, redness, or pain persists.


Ingestion:

If Disodium phosphate anhydrous is accidentally ingested, do not induce vomiting unless instructed to do so by a medical professional.
Rinse the mouth with water and provide the affected person with small sips of water.
Do not give anything by mouth if the person is unconscious, convulsing, or displaying symptoms of severe distress.
Seek immediate medical attention or contact a poison control center for guidance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When working with Disodium phosphate anhydrous, wear appropriate PPE, including safety goggles, gloves, and a lab coat or protective clothing to minimize the risk of skin and eye contact.
Respiratory protection may be necessary if there is a potential for inhalation exposure.

Ventilation:
Use adequate ventilation, such as local exhaust or mechanical ventilation, to control airborne dust and maintain air quality within recommended exposure limits.
Ensure the workplace has proper airflow.

Avoiding Contact:
Minimize skin and eye contact by exercising caution when handling the chemical.
Do not touch your face, eyes, or mouth while working with Disodium phosphate anhydrous, and wash hands thoroughly after handling.

Spill Management:
Implement spill control measures to prevent the spread of Disodium phosphate anhydrous in case of accidental spills. Use appropriate absorbents and follow established spill response procedures.
Avoid creating dust during cleanup.

Avoid Ingestion:
Do not eat, drink, or smoke while working with the chemical.
Always wash hands and face before eating, drinking, or using tobacco products.

Labeling and Storage:
Ensure containers of Disodium phosphate anhydrous are clearly labeled with the product name, hazard information, and appropriate safety labels.
Store the chemical in its original container or an approved container, and keep it tightly closed when not in use.

Segregation:
Store Disodium phosphate anhydrous away from incompatible substances, such as strong acids, bases, and reducing agents.
Maintain separation to prevent chemical reactions.

Handling Equipment:
Use dedicated equipment (e.g., scoops, containers) when handling the chemical to prevent contamination of equipment used for other substances.

Safe Working Practices:
Follow safe laboratory or workplace practices and adhere to established safety protocols, including emergency response procedures.


Storage:

Location:
Store Disodium phosphate anhydrous in a cool, dry, and well-ventilated area, away from direct sunlight and heat sources.
Ensure the storage area is designed to minimize temperature fluctuations.

Separation:
Keep the chemical away from incompatible materials to prevent potential chemical reactions or hazards.

Containment:
Store the chemical in approved containers that are properly labeled and sealed.
Ensure containers are in good condition without leaks or damage.

Accessibility:
Store containers of Disodium phosphate anhydrous in a way that allows easy access and minimizes the risk of spills during retrieval.

Incompatibility:
Be aware of the chemical's incompatibility with certain substances, and do not store it near these incompatible materials.

Temperature Control:
Maintain storage temperatures within recommended limits to prevent exposure to extreme heat or cold, as well as temperature-related changes in the chemical's properties.

Security:
Ensure that access to storage areas is restricted to authorized personnel only to prevent unauthorized handling or tampering with the chemical.

Inventory Control:
Keep an inventory of Disodium phosphate anhydrous, including tracking the quantity on hand, monitoring expiration dates, and conducting regular inspections for signs of damage or degradation.

Emergency Preparedness:
Maintain appropriate spill response equipment and supplies in the storage area.
Ensure that spill containment measures are readily available.



SYNONYMS


Sodium phosphate dibasic anhydrous
Disodium hydrogen phosphate anhydrous
Sodium hydrogen phosphate
Sodium phosphate, dibasic
Sodium phosphate, secondary
Sodium hydrogen orthophosphate
Disodium hydrogen orthophosphate
Sodium phosphate, Na2HPO4
DSPA
Sodium phosphate, heptahydrate-free
Disodium hydrogen orthophosphate anhydrous
Sodium phosphate, dibasic, anhydrous
Dodecasodium triphosphate
Disodium phosphate, anhydrous
Secondary sodium phosphate
Disodium orthophosphate anhydrous
Sodium orthophosphate, dibasic
Sodium hydrogen orthophosphate, anhydrous
Sodium phosphate, secondary, heptahydrate-free
Disodium hydrogen orthophosphate, heptahydrate-free
Sodium hydrogen phosphate, anhydrous
Sodium phosphate, dibasic, heptahydrate-free
Disodium orthophosphate, heptahydrate-free
Secondary sodium phosphate, anhydrous
Sodium hydrogen orthophosphate, dodecahydrate-free
Sodium phosphate, anhydrous
Sodium phosphate, dibasic, anhydrous
Disodium hydrogen phosphate, anhydrous
Disodium orthophosphate
Sodium orthophosphate, secondary
Sodium phosphate secondary, anhydrous
Sodium phosphate dibasic, heptahydrate-free
Sodium phosphate, dodecahydrate-free
Sodium phosphate, dibasic, heptahydrate-deprived
DSPA, anhydrous
Secondary sodium phosphate, heptahydrate-free
Disodium phosphate, heptahydrate-deprived
Disodium hydrogen orthophosphate, dodecahydrate-free
Sodium hydrogen phosphate, anhydrous
Sodium phosphate, dibasic, heptahydrate-restricted
Disodium orthophosphate, dodecahydrate-free
Sodium hydrogen orthophosphate, heptahydrate-free
Sodium phosphate, secondary, heptahydrate-deprived
Disodium phosphate, anhydrous and heptahydrate-deprived
Secondary sodium phosphate, anhydrous and heptahydrate-free
Sodium hydrogen orthophosphate, dodecahydrate-restricted
Sodium phosphate, dibasic, anhydrous and heptahydrate-free
DSPA, anhydrous and heptahydrate-deprived
Disodium hydrogen orthophosphate, heptahydrate-free and dodecahydrate-restricted
Disodium phosphate, heptahydrate-deprived and dodecahydrate-free
DISODIUM PHOSPHATE ANHYDROUS (FOOD)
DESCRIPTION:

Disodium phosphate anhydrous (Food), or disodium hydrogen phosphate, or sodium phosphate dibasic, is the inorganic compound with the formula Na2HPO4.
Disodium phosphate anhydrous (Food) is one of several sodium phosphates.
The salt is known in anhydrous form as well as forms with 2, 7, 8, and 12 hydrates.
All are water-soluble white powders, the anhydrous salt being hygroscopic.


CAS Number, 7558-79-4
EC Number, 231-448-7


Disodium phosphate anhydrous (Food), Dibasic, Anhydrous, FCC is an additive used as an antioxidant, sequestrant and a pH regulator with very high buffering capacity widely used in foods.
The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications.

Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.


Sodium phosphate, dibasic appears as a colorless to white crystalline solid.
Disodium phosphate anhydrous (Food) is Soluble in water.
The primary hazard is the threat to the environment.

Immediate steps should be taken to limit spread to the environment.
Disodium phosphate anhydrous (Food) is Used as a fertilizer, in pharmaceuticals, in food processing, and for many other uses.


Also known as disodium hydrogen orthophosphate dodecahydrate, disodium phosphate dodecahydrate, sodium hydrogene dibasic.
Disodium phosphate anhydrous (Food) is a white powder that is highly hygroscopic and water soluble.
Disodium phosphate anhydrous (Food) is therefore used commercially as an anti-caking additive in powdered products.


Disodium phosphate anhydrous (Food) is Used as a pH buffer, stabilizer and emulsifier in processed cheese, condensed milk, instant pudding and other food applications.
The pH of disodium hydrogen phosphate water solution is between 8.0 and 11.0, meaning it is moderately basic:
HPO42− + H2O ⇌ H2PO4− + OH−

Disodium phosphate anhydrous (Food) is a white, powdered, non-aggressive and non-flammable substance.

Disodium phosphate anhydrous (Food) is often used as an emulsifier and a buffering agent for the production of processed cheese, as well as an additive to prevent the gelation of milk.
And addition of Disodium Phosphate Anhydrous can shorten the cooking time of pasta.


Disodium Phosphate, Anhydrous (DSPa) Granular & Powder is a white, odorless, free flowing powder.
This product is known for its alkalinity and is used as a buffering agent, protein modifier, stabilizer, and emulsifying agent.
DSP is commonly used during production of spray dried cheese and nonfat milk powders.

DSP protects the milk proteins from heat dehydration allowing the proteins to remain dispersed during the spray drying process, which assists in the solubility of the powders upon reconstitution with water.
DSP also stabilizes the emulsion to enhance flavor, body, and appearance of the final product.


Disodium phosphate anhydrous (Food) is made with a simple chemical reaction between phosphoric acid (H3PO4) and sodium hydroxide.
Phosphoric acid is a mineral acid.
Disodium phosphate anhydrous (Food) neutralizes with sodium hydroxide, which acts as an alkaline substance during the reaction.

Sodium atoms replace two of the three hydrogen atoms in the phosphoric acid and disodium phosphate is formed.
When used according to the FDA’s good manufacturing practices, disodium phosphate is generally recognized as safe.
Though we often think of processed food as a byproduct of the mid-20th century, sodium phosphates have been used in food production for over a century.

Phosphates were used in cheese production as early as 1895.
Likewise, sodium phosphates have historically been used in processed cheese, evaporated milk, and other fluid milk products.



pH Control In Packaged Foods:
Among the most common uses of disodium phosphate is as a neutralizing agent.
Disodium phosphate anhydrous (Food) acts as a buffering solution that helps control pH.
Buffering solutions, a type of water-soluble solution known as aqueous solutions, are created by mixing a weak acid and its conjugate base.

When a harsh acid or base is added to the solution, the pH of the solution as a whole is minimally affected.
Many consumable liquids require diligent monitoring of pH to keep them in the right state.
For instance, creamy milk can quickly become tangy cottage cheese by reducing the pH of the milk by adding an acid.

Keeping the pH stable also contributes to food safety.
Foods with a pH of 4.6 or lower do not provide a hospitable environment for bacteria like Clostridium botulinum to grow.


Stabilizing Our Dairy:
Most people love cheese but making it would be difficult without disodium phosphate.
Disodium phosphate anhydrous (Food) acts as an emulsifier that keeps fat and water from separating during the cheese-making process.
This helps us get the richest and creamiest cheese possible.


In evaporated milk, Disodium phosphate anhydrous (Food) helps keep the butterfat from separating in the can and prevents an unpleasant gel from forming.
And if you are a fan of whipped cream, you can thank disodium phosphate for the pleasure of picking it up at your local grocery store.
Disodium phosphate is used as a processing agent in heavy whipping cream where it binds to the natural minerals in milk.

Disodium phosphate anhydrous (Food) prevents the heavy cream from becoming unmanageable and coating the equipment during processing.


Controlling Texture & Food Preservation:
Salt was the first preservative used to keep meat, seafood, pork, and poultry safe for consumption.
Over time, food manufacturers have incorporated disodium phosphate as a means of food preservation.

But the benefit of using disodium phosphate on meats does not stop at preservation.
Disodium phosphate anhydrous (Food) can improve the meat’s tenderness and make it appear juicier.

Americans are lucky enough to live in a world where rich foods are just a shopping trip away.
And we have come to rely on these convenience foods.
The world of chemistry allows food manufacturers to create safe, enjoyable products that make our lives easier.

Disodium phosphate anhydrous (Food) is just one of the sodium phosphates used in the making of these packaged foods.
But there are numerous other sodium phosphates used in and out of the food manufacturing industry.


PRODUCTION AND REACTIONS OF DISODIUM PHOSPHATE ANHYDROUS (FOOD):
Disodium phosphate anhydrous (Food) can be generated by neutralization of phosphoric acid with sodium hydroxide:
H3PO4 + 2 NaOH → Na2HPO4 + 2 H2O

Industrially It is prepared in a two-step process by treating dicalcium phosphate with sodium bisulfate, which precipitates calcium sulfate:
CaHPO4 + NaHSO4 → NaH2PO4 + CaSO4

In the second step, the resulting solution of monosodium phosphate is partially neutralized:
NaH2PO4 + NaOH → Na2HPO4 + H2O



USES OF DISODIUM PHOSPHATE ANHYDROUS (FOOD):
It is used in conjunction with trisodium phosphate in foods and water softening treatment.
In foods, it is used to adjust pH.
Its presence prevents coagulation in the preparation of condensed milk.

Similarly, Disodium phosphate anhydrous (Food) is used as an anti-caking additive in powdered products.
Disodium phosphate anhydrous (Food) is used in desserts and puddings, e.g. Cream of Wheat to quicken cook time, and Jell-O Instant Pudding for thickening.
In water treatment, it retards calcium scale formation.

Disodium phosphate anhydrous (Food) is also found in some detergents and cleaning agents.
Heating solid disodium phosphate gives the useful compound tetrasodium pyrophosphate:[citation needed]
2 Na2HPO4 → Na4P2O7 + H2O


Laxative:
Monobasic and dibasic sodium phosphate are used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy

DISODIUM PHOSPHATE IN FOOD:
It’s very common in processed and packaged foods.
Some of the purposes Disodium phosphate anhydrous (Food) serves in the manufacturing process are:
Disodium phosphate anhydrous (Food) is an Emulsifier.

Disodium phosphate anhydrous (Food) is a chemical that helps to bind fats and water together.
Fats don’t mix with many other liquids without help.

Emulsifiers have a chemical structure that helps them mix.
Disodium phosphate is a helpful emulsifier for dairy products and other foods.
Cheese, whipped cream, milk, and other dairy products have unique textures and consistencies because of disodium phosphate.


SAFETY INFORMATION ABOUT DISODIUM PHOSPHATE ANHYDROUS (FOOD):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product





CHEMICAL AND PHYSICAL PROPERTIES OF DISODIUM PHOSPHATE ANHYDROUS (FOOD):
Chemical formula, Na2HPO4
Molar mass, 141.96 g/mol (anhydrous)
177.99 g/mol (dihydrate)
268.07 g/mol (heptahydrate)
Appearance, White crystalline solid
Odor, odorless
Density, 1.7 g/cm3
Melting point, 250 °C (482 °F; 523 K) decomposes
Solubility in water, 7.7 g/100 ml (20 °C)
11.8 g/100 mL (25 °C, heptahydrate)
Solubility, insoluble in alcohol
log P, -5.8
Acidity (pKa), 2.15, 6.82, 12.35
Magnetic susceptibility (χ), −56.6•10−6 cm3/mol
Refractive index (nD), 1.35644..1.35717 at 20°C
Minimum Assay: >98.5%
Molecular Formula: HNa2O4P
Molecular Weight: 141.96
Appearance Form: White Crystalline powder
pH: 8.9 – 9.2 at 50 g/l at 25 °C
PO2 Content: 49.7%
Vapour density: 4.90 – (Air = 1.0)
Relative density: 1.520 g/cm3
Water solubility: soluble
Relative vapour density 4.90 – (Air = 1.0)
Arsenic (As): <1ppm
Fluoride (F): <10ppm
Lead (Pb): <1ppm
Cadmium (Cd): <1ppm
Mercury (Hg): <0.5ppm
Insoluble Matter: <0.02%
Loss on Drying: <0.1%
Molecular Weight
141.959 g/mol
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
141.94078407 g/mol
Monoisotopic Mass
141.94078407 g/mol
Topological Polar Surface Area
83.4Ų
Heavy Atom Count
7
Formal Charge
0
Complexity
46.5
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes
PSA:
95.4
XLogP3:
-0.82380
Appearance:
White Crystals
Density:
1,52 g/cm3
Melting Point:
35 °C
Boiling Point:
158ºC at 760 mmHg
Refractive Index:
1.429
Water Solubility:
H2O: 218 g/L (20 ºC)
Storage Conditions:
Store at +15°C to +25°C.
Taste:
Saline taste



SYNONYMS OF DISODIUM PHOSPHATE ANHYDROUS (FOOD):
Dibasic sodium phosphate
Disodium acid phosphate
Disodium phosphate
Secondary sodium phosphate
Disodium hydrogen monophosphate
Disodium hydrogen orthophosphate
Disodium hydrogen phosphate
dibasic sodium phosphate, anhydrous
disodium acid phosphate
disodium hydrogen phosphate
disodium hydrogen phosphate anhydrous
monosodium dihydrogen phosphate
neutral sodium hydrogen phosphate
phosphoric acid, disodium salt
phosphoric acid, disodium salt, 32P-labeled
phosphoric acid, disodium salt, anhydrous
phosphoric acid, disodium salt, dodecahydrate
phosphoric acid, disodium salt, heptahydrate
phosphoric acid, monosodium salt
phosphoric acid, monosodium salt, anhydrous
phosphoric acid, sodium (2:3) salt
phosphoric acid, sodium salt
phosphoric acid, trisodium salt
phosphoric acid, trisodium salt , 32P-labeled
phosphoric acid, trisodium salt , dodecahydrate
sodium biphosphate
sodium dihydrogen orthophosphate
sodium dihydrogen phosphate
sodium hydrophosphate
sodium phosphate
sodium phosphate monobasic anhydrous
sodium phosphate, dibasic
sodium phosphate, dibasic (anhydrous)
sodium phosphate, disodium salt
sodium phosphate, monobasic
sodium phosphate, monobasic anhydrous
sodium phosphate, tribasic
sodium phosphate, tribasic, dodecahydrate
trisodium phosphate
trisodium phosphate dodecahydrate
7558-79-4
Disodium hydrogen phosphate
Sodium phosphate dibasic
DISODIUM PHOSPHATE
Disodium hydrogenorthophosphate
Sodium phosphate, dibasic
Acetest
Dibasic sodium phosphate
disodium hydrogenphosphate
Disodium acid phosphate
Soda phosphate
Phosphoric acid, disodium salt
Exsiccated sodium phosphate
Disodium orthophosphate
Sodium hydrogenphosphate
Sodium hydrogen phosphate
Sodium monohydrogen phosphate
FEMA No. 2398
secondary Sodium phosphate
disodium;hydrogen phosphate
Disodium acid orthophosphate
sec-Sodium phosphate
Disodium phosphate, anhydrous
Disodium monohydrogen phosphate
Disodium hydrogen phosphate, anhydrous
Hydrogen disodium phosphate
SODIUM PHOSPHATE, DIBASIC, ANHYDROUS
Sodium phosphate, dibasic (anhydrous)
SODIUM PHOSPHATE, DIBASIC ANHYDROUS
Na2HPO4
Phosphoric acid, sodium salt (1:2)
Disodium hydrogen monophosphate
22ADO53M6F
INS NO.339(II)
DSP
CHEBI:34683
INS-339(II)
Dibasic sodium phosphate anhydrous
dibasic sodium phosphate, anhydrous
E-339(II)
MFCD00003496
phosphoric acid, disodium salt, anhydrous
Phosphate of soda
Caswell No. 778
Disodium hydrophosphate
Disodium phosphoric acid
FEMA Number 2398
Fleet enema
Natriumphosphat [German]
Sodium phosphate (NaHPO4)
Sodium phosphate, exsiccated
CCRIS 5931
HSDB 376
Sodium orthophosphate, secondary
Sodium acid phosphate, anhydrous
Sodium Phosphate dibasic anhydrous
EINECS 231-448-7
EPA Pesticide Chemical Code 076403
Sodium monohydrogen phosphate (2:1:1)
UNII-22ADO53M6F
Disodium hydrogen orthophosphate
Disodium phospahte
Sodiumphosphatedibasic
Disodiumhydrogenphosphate
sodium hydrogen-phosphate
disodium hydrogen-phosphate
Disodium phosphate anhydrous
EC 231-448-7
Sorensen's sodium phosphate
di-sodium hydrogen phosphate
phosphoric acid disodium salt
sodium hydrogen orthophosphate
SODIUM PHOSPHATE [FHFI]
DTXSID1026039
DISODIUM PHOSPHATE [HSDB]
DISODIUM PHOSPHATE [INCI]
BNIILDVGGAEEIG-UHFFFAOYSA-L
Sodium phosphate,dibasic,anhydrous
BCP13559
Sodium hydrogen phosphate, anhydrous
Sodium phosphate dibasic, ACS grade
Disodium Hydrogen Phosphate Submicron
AKOS015902440
AKOS015950661
CCG-266159
DB14502
SODIUM PHOSPHATE, DIBASIC [MI]
DISODIUM PHOSPHATE [EP MONOGRAPH]
SODIUM PHOSPHATE DIBASIC [WHO-DD]
Sodium phosphate dibasic, ACS/HPLC grade
Sodium phosphate dibasic, biochemical grade
FT-0625321
Sodium phosphate dibasic, Trace metals grade
A937532
Q418448
SODIUM PHOSPHATE, DIBASIC, ANHYDROUS [II]
SODIUM PHOSPHATE,DIBASIC,ANHYDROUS [VANDF]
Water Supply QC Check Sample: o-Phosphate Nutrients
Disodium hydrogen orthophosphate;Sodium hydrogen phosphate
SODIUM PHOSPHATE, DIBASIC ANHYDROUS [ORANGE BOOK]
SODIUM PHOSPHATE, DIBASIC, ANHYDROUS [ORANGE BOOK]
VISICOL COMPONENT SODIUM PHOSPHATE, DIBASIC ANHYDROUS
OSMOPREP COMPONENT SODIUM PHOSPHATE, DIBASIC ANHYDROUS
SODIUM PHOSPHATE, DIBASIC ANHYDROUS COMPONENT OF VISICOL
SODIUM PHOSPHATE, DIBASIC ANHYDROUS COMPONENT OF OSMOPREP





DISODIUM PHOSPHATE DIHYDRATE

Disodium phosphate dihydrate, often represented as Na2HPO4 • 2H2O, is a chemical compound.
Disodium phosphate dihydrate is a hydrated form of disodium phosphate, meaning it contains two molecules of water (H2O) in its crystalline structure.
Disodium phosphate dihydrate is commonly used in various industrial applications, including as a food additive, a buffering agent, and a component in cleaning and detergents.
Its chemical structure consists of two sodium (Na) ions, one hydrogen phosphate (HPO4^2-) ion, and two water molecules (H2O).

CAS Number: 10028-24-7
EC Number: 231-448-7



APPLICATIONS


Disodium phosphate dihydrate is commonly used as a food additive and pH regulator in the food industry, where it helps maintain the stability and texture of processed foods.
Disodium phosphate dihydrate serves as an emulsifying agent in food products, improving the mixing of water and fats.

In the dairy industry, it is used in the production of processed cheeses, preventing them from becoming too oily.
Disodium phosphate dihydrate is added to canned soups and broths to control pH and enhance their flavor.
Disodium phosphate dihydrate is used as a leavening agent in baked goods, such as bread and cakes, to help them rise during baking.

Disodium phosphate dihydrate can be found in breakfast cereals to improve texture and crispness.
In the beverage industry, it is used as a stabilizer and buffering agent in powdered drink mixes.

The pharmaceutical industry uses it as a disintegrant in tablet formulations, aiding in the rapid breakdown of tablets upon ingestion.
In the water treatment sector, it acts as a water softener, reducing water hardness by binding to calcium and magnesium ions.

Dental products like toothpaste incorporate it to maintain the pH balance and improve product stability.
In the cleaning industry, it enhances the cleaning efficiency of detergents and cleaning agents.

Disodium phosphate dihydrate is employed in some fire-extinguishing agents to enhance their firefighting properties.
Disodium phosphate dihydrate plays a crucial role in the formulation of synthetic detergents and soaps, improving their foaming properties.
Disodium phosphate dihydrate is used in construction materials like cement, where it helps control the setting time.
Disodium phosphate dihydrate can be found in certain fireproofing materials, enhancing fire resistance in building materials.
In the cosmetics and personal care industry, it is used in hair coloring products to maintain product stability and pH balance.

Disodium phosphate dihydrate is added to oral rehydration solutions, helping restore electrolyte balance in cases of dehydration.
Disodium phosphate dihydrate contributes to the creation of adhesive products, improving bonding properties and consistency.

In the agriculture sector, it is employed to adjust the pH of irrigation water and optimize soil pH for crop growth.
The automotive industry uses it in some specialty welding fluxes to protect welds from contamination and ensure high-quality joints.

Certain laboratory and research processes rely on it as a buffering agent and pH regulator.
Disodium phosphate dihydrate is used in the preparation of ceramics, glazes, and clay bodies to enhance plasticity and green strength.

Disodium phosphate dihydrate is found in some drilling fluids used in the oil and gas industry, aiding in viscosity control during drilling operations.
Disodium phosphate dihydrate is a common component in non-alcoholic beverages, enhancing product stability and flavor.

In the textile industry, Disodium phosphate dihydrate is used as a sizing agent to improve the quality and durability of fabrics, particularly in weaving and textile finishing.
In the paper and pulp industry, Disodium phosphate dihydrate is used as a pulping agent to extract cellulose fibers from wood, improving the papermaking process.
Disodium phosphate dihydrate finds application in the textile industry as a flame retardant and finishing agent for fabrics, enhancing their resistance to fire.

In the brewing industry, it can be used to adjust the pH of brewing water, leading to improved beer quality.
Disodium phosphate dihydrate is employed in the manufacture of ceramics, where it enhances glazes and slip casting formulations.
Disodium phosphate dihydrate is used in the production of air fresheners and deodorizers, helping to neutralize odors effectively.
Disodium phosphate dihydrate is added to shampoos and hair conditioners to adjust their pH and improve hair texture.

In the paint and coating industry, it serves as a pH buffer, contributing to the stability of paint formulations.
Disodium phosphate dihydrate can be found in metal cleaning and plating solutions to enhance cleaning efficiency and prevent corrosion.
Disodium phosphate dihydrate is used as a stabilizing agent in some medical diagnostic reagents to ensure accurate test results.

In the petroleum industry, it plays a role in drilling mud formulations, aiding in viscosity control during drilling operations.
Disodium phosphate dihydrate is used in the manufacturing of detergents and laundry products to improve their cleaning performance.

Disodium phosphate dihydrate is employed in the construction of fire-resistant drywall to enhance its fireproofing properties.
Disodium phosphate dihydrate is used as a pH regulator in the production of soap bars and liquid soaps, ensuring their mildness and effectiveness.
In the leather industry, it is added to tanning solutions to improve the tanning process and leather quality.

Disodium phosphate dihydrate finds application in the creation of specialty adhesives for various industrial and consumer uses.
Disodium phosphate dihydrate can be found in cooling water systems as a corrosion inhibitor, protecting industrial equipment from damage.
Disodium phosphate dihydrate is used in the formulation of industrial floor cleaners to remove stubborn stains and dirt.
Disodium phosphate dihydrate is employed in the construction industry as a setting regulator for cement-based products, controlling setting times.

In the dairy industry, it contributes to the production of evaporated milk by enhancing the milk's stability and texture.
Disodium phosphate dihydrate is utilized in oil well stimulation to control pH and improve the efficiency of stimulation fluids.
Disodium phosphate dihydrate can be found in corrosion protection coatings to enhance their durability and resistance to environmental factors.
Disodium phosphate dihydrate is used in the production of synthetic rubber, improving the dispersion of rubber components.
In the photography industry, it can be found in the formulation of photographic developers.

Disodium phosphate dihydrate is a valuable component in fire extinguishing powders, enhancing their firefighting properties.
Disodium phosphate dihydrate plays a role in the creation of adhesive formulations for various applications, including woodworking and laminates.

In the agricultural industry, Disodium phosphate dihydrate is used as a component in fertilizer formulations to provide essential phosphorus and adjust soil pH.
Disodium phosphate dihydrate is employed in the manufacturing of fire-resistant textiles and fabrics for applications such as firefighter gear and industrial safety clothing.
In the cosmetics industry, it is used as a buffering agent in skincare products to control and maintain the pH levels of creams, lotions, and serums.

Disodium phosphate dihydrate plays a role in the production of household cleaning products, such as bathroom cleaners, where it assists in removing stubborn stains.
Disodium phosphate dihydrate is used in the formulation of specialized lubricants and cutting fluids for metalworking, improving the performance and efficiency of machining processes.

In the production of dry mixes for soups, sauces, and gravies, it acts as a thickening and stabilizing agent, ensuring consistent texture and flavor.
Disodium phosphate dihydrate is utilized in water-based drilling fluids in the oil and gas industry to enhance viscosity and control fluid properties during drilling operations.

Disodium phosphate dihydrate is added to boiler water treatment chemicals to prevent scale buildup and corrosion in industrial boiler systems.
Disodium phosphate dihydrate finds application in the formulation of electrolyte solutions for use in batteries and fuel cells, helping maintain efficient ion transport.
Disodium phosphate dihydrate is used in the production of dental products such as toothpaste and mouthwash to help control pH and maintain product stability.

In the manufacture of fire-resistant paints and coatings, it enhances the fireproofing properties of surfaces, such as building materials and steel structures.
Disodium phosphate dihydrate is employed in the creation of effervescent tablets, which release carbon dioxide upon contact with water, making them useful in various pharmaceutical and dietary supplements.
Disodium phosphate dihydrate is used as a buffering agent in laboratory and biotechnological applications, helping to maintain consistent pH levels in chemical reactions.

In the agricultural sector, it is incorporated into soil amendments to adjust soil pH and provide essential nutrients for plant growth.
Disodium phosphate dihydrate is found in some pharmaceutical preparations, including antacids, where it helps neutralize excess stomach acid.

Disodium phosphate dihydrate is used in the production of electrolyte solutions for intravenous fluids, helping to maintain electrolyte balance in medical treatments.
Disodium phosphate dihydrate serves as a pH regulator in the formulation of cosmetics, improving product stability and consistency.
Disodium phosphate dihydrate can be found in flame-retardant coatings for wood and textiles, enhancing their fire resistance.

In the printing industry, it is used in fountain solutions to maintain pH and improve the quality of print.
Disodium phosphate dihydrate is employed in the manufacturing of synthetic fire logs and fire starters, enhancing their combustion properties.
Disodium phosphate dihydrate plays a role in the creation of specialty concrete and mortar mixtures, improving their workability and setting times.

In the glass and ceramics industry, it is used as a flux to lower the melting point of materials and promote uniform melting in kilns.
Disodium phosphate dihydrate can be found in refrigeration and cooling systems as a corrosion inhibitor to protect against rust and scale buildup.

Disodium phosphate dihydrate is added to sugar-based confectionery products, such as candy and marshmallows, to control texture and prevent crystallization.
Disodium phosphate dihydrate is used in the formulation of dietary supplements to provide essential phosphorus and assist in the absorption of minerals and nutrients in the body.

In the textile industry, Disodium phosphate dihydrate is used in dyeing and printing processes as a leveling agent to ensure even color distribution on fabrics.
Disodium phosphate dihydrate is employed in the formulation of heat treatment baths for metals, assisting in the hardening and tempering of steel.
In the production of ceramics, it serves as a flux to lower the melting point of raw materials and improve their fusion during firing.

Disodium phosphate dihydrate is found in some baby formula products, where it contributes to the regulation of pH and stability.
In the manufacturing of powdered beverages, such as instant coffee and cocoa, it is used as a dispersing and stabilizing agent to prevent clumping.
Disodium phosphate dihydrate plays a role in the construction industry as an ingredient in plaster formulations, enhancing their workability and setting times.
Disodium phosphate dihydrate is used in the creation of photovoltaic (solar) panels, helping to control the pH in the production of solar cell coatings.

Disodium phosphate dihydrate can be found in some baking powder formulations, acting as a leavening agent to help baked goods rise.
In the preservation of canned vegetables, it helps maintain color and texture during the canning process.
Disodium phosphate dihydrate is employed in the production of effervescent denture cleaning tablets, which dissolve in water to clean dentures and remove stains.
Disodium phosphate dihydrate is used in water treatment plants to reduce the levels of heavy metals, such as lead and cadmium, through precipitation and coagulation.
In the formulation of pesticide sprays, it can serve as a pH buffer to optimize the effectiveness of the active ingredients.

Disodium phosphate dihydrate is used in the preparation of pH-adjusted nutrient solutions for hydroponic farming and plant cultivation.
Disodium phosphate dihydrate is found in fire extinguishing foam concentrates, enhancing their fire suppression capabilities.
Disodium phosphate dihydrate can be incorporated into glass and crystal manufacturing to control the composition and melting characteristics of glass batches.

In the production of synthetic rubber, it improves the dispersion of fillers and additives, leading to improved rubber performance.
Disodium phosphate dihydrate is utilized in the cosmetic industry as a thickening agent in creams and lotions.
Disodium phosphate dihydrate can be found in tooth whitening products, where it aids in pH control and product stability.

In the brewing industry, it plays a role in the production of beer, helping to adjust the pH of brewing water and optimize the brewing process.
Disodium phosphate dihydrate is used in the creation of specialized drilling fluids for oil and gas exploration, aiding in borehole stability.

Disodium phosphate dihydrate is employed in the production of photographic chemicals and developers for film and prints.
Disodium phosphate dihydrate is used in the formulation of dietary supplements, helping to provide essential phosphorus and support various health-related claims.

In the production of antifreeze and coolant solutions for automotive and industrial applications, it contributes to pH control and corrosion protection.
Disodium phosphate dihydrate is found in cooling water systems to control scale and corrosion in industrial cooling equipment.
Disodium phosphate dihydrate can be incorporated into specialty cleaning products for the removal of rust and mineral deposits in industrial settings.



DESCRIPTION


Disodium phosphate dihydrate, often represented as Na2HPO4 • 2H2O, is a chemical compound.
Disodium phosphate dihydrate is a hydrated form of disodium phosphate, meaning it contains two molecules of water (H2O) in its crystalline structure.
Disodium phosphate dihydrate is commonly used in various industrial applications, including as a food additive, a buffering agent, and a component in cleaning and detergents.
Its chemical structure consists of two sodium (Na) ions, one hydrogen phosphate (HPO4^2-) ion, and two water molecules (H2O).

Disodium phosphate dihydrate, with its chemical formula Na2HPO4 • 2H2O, is a hydrated salt of sodium.
Disodium phosphate dihydrate is a white, crystalline powder with a molecular weight of 177.99 g/mol.

The dihydrate form indicates that it contains two molecules of water (H2O) within its crystal structure.
Disodium phosphate dihydrate is highly soluble in water, producing a clear and colorless solution.
Disodium phosphate dihydrate has a slightly alkaline pH when dissolved in water, typically around 9.0, making it useful as a buffering agent.

Disodium phosphate dihydrate is odorless and has a slightly salty taste.
Disodium phosphate dihydrate is non-flammable and does not pose significant fire hazards.
Disodium phosphate dihydrate is often used in the food industry as a food additive and a pH regulator.
In the food industry, it serves as an emulsifier, a sequestrant, and a texturizer.

As a food additive, it can be found in processed cheeses, canned soups, and other food products.
Disodium phosphate dihydrate is used as a leavening agent in baked goods to help them rise during baking.

In the pharmaceutical industry, Disodium phosphate dihydrate is used as a disintegrant in tablet formulations.
Disodium phosphate dihydrate is employed in the water treatment industry to control water hardness by binding to calcium and magnesium ions.
Disodium phosphate dihydrate finds applications in the preparation of dental products, such as toothpaste, to adjust pH and improve product stability.

Disodium phosphate dihydrate is a common component in some cleaning agents and detergents to enhance their cleaning efficiency.
In the cosmetic and personal care industry, it helps maintain the stability of various products.
Disodium phosphate dihydrate is used in some fire-extinguishing agents, enhancing their firefighting properties.
Disodium phosphate dihydrate plays a role in the creation of synthetic detergents and soaps.
In the construction industry, it can be found in certain cement formulations.

Disodium phosphate dihydrate is used in the preparation of oral rehydration solutions for medical purposes.
Disodium phosphate dihydrate contributes to the formulation of adhesive products, improving bonding properties and consistency.

In the agricultural sector, it is employed for soil and water management, optimizing pH for crop growth.
Disodium phosphate dihydrate is used in some specialty welding fluxes in the automotive and manufacturing industries.

Disodium phosphate dihydrate is involved in the formulation of certain fireproofing materials.
Disodium phosphate dihydrate is an essential chemical in various laboratory and industrial processes due to its versatility as a buffering agent, pH regulator, and emulsifying agent.



PROPERTIES


Chemical Formula: Na2HPO4 • 2H2O
Molecular Weight: 177.99 g/mol
Appearance: White, crystalline powder
State: Solid
Solubility: Highly soluble in water, forming a clear and colorless solution
pH Level (in aqueous solution): Typically around 9.0, slightly alkaline
Taste: Slightly salty
Odor: Odorless
Density: Varies with conditions, but typically around 1.52 g/cm³
Melting Point: Decomposes without a distinct melting point
Boiling Point: Decomposes without a distinct boiling point
Water Content: Contains two molecules of water (dihydrate) in its crystal structure
Solubility in Other Solvents: Insoluble in organic solvents
Hygroscopicity: Absorbs moisture from the air
Stability: Stable under normal conditions
Flammability: Non-flammable
Flash Point: Not applicable
Autoignition Temperature: Not applicable
Corrosivity: Not corrosive
Vapor Pressure: Negligible
Viscosity: Varies with concentration and temperature
Crystal Structure: Forms monoclinic crystals
Molecular Structure: Consists of two sodium (Na) ions, one hydrogen phosphate (HPO4^2-) ion, and two water molecules (H2O)
pH Buffering Capacity: Effective buffering agent
Compatibility: Compatible with many other chemicals and compounds



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air and provide artificial respiration if breathing is difficult.
Seek medical attention if respiratory distress persists.


Skin Contact:

In case of skin contact, immediately remove contaminated clothing.
Wash the affected area with plenty of water and mild soap for at least 15 minutes.
Seek medical attention if irritation, redness, or other adverse skin reactions occur.


Eye Contact:

If the compound comes into contact with the eyes, immediately rinse the eyes with gently flowing lukewarm water, keeping eyelids open to ensure thorough flushing.
Continue flushing for at least 15 minutes, holding the eyelids apart to prevent further contact.
Seek immediate medical attention, and provide information about the chemical involved.


Ingestion:

If ingested, do not induce vomiting unless directed by a medical professional.
Rinse the mouth with water and drink plenty of water to dilute the chemical.
Seek immediate medical attention and provide information about the ingestion, including the quantity and time of ingestion.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling Disodium phosphate dihydrate, wear appropriate personal protective equipment, including safety goggles, gloves, and a lab coat or protective clothing, to minimize contact with the skin and eyes.

Ventilation:
Use adequate ventilation, such as local exhaust, mechanical ventilation, or respiratory protection, when working with this compound to control airborne concentrations and prevent inhalation exposure.

Avoid Contact:
Minimize skin contact and avoid inhaling dust or aerosols.
Wash hands and any exposed skin thoroughly after handling the compound.

Prevent Contamination:
Keep containers tightly sealed when not in use to prevent contamination and protect the product from moisture.
Store in dedicated containers and avoid cross-contamination with incompatible materials.

Avoid Mixing:
Do not mix Disodium phosphate dihydrate with incompatible substances, such as strong acids, strong bases, or reducing agents, as this can lead to hazardous reactions.
Consult the Safety Data Sheet (SDS) for specific incompatibilities.

Spills and Leaks:
In case of spills or leaks, contain and collect the material using appropriate absorbent materials and tools.
Avoid creating dust.
Dispose of waste material in accordance with local, state, and federal regulations.


Storage:

Storage Conditions:
Store Disodium phosphate dihydrate in a cool, dry, well-ventilated area, away from incompatible materials.
Keep containers tightly closed to prevent moisture absorption.

Temperature:
Maintain storage temperatures between 15°C and 30°C (59°F and 86°F).
Avoid exposure to extreme heat, open flames, and direct sunlight.

Moisture Control:
Protect the compound from excessive humidity and moisture, as it can lead to caking and reduced product quality.
Use desiccants or humidity control measures if necessary.

Separation:
Store Disodium phosphate dihydrate away from strong acids, strong bases, and reducing agents to prevent adverse reactions.
Use separate storage areas or dedicated containers for different chemical products.

Labeling:
Ensure that containers are properly labeled with the chemical name, hazard information, and safety precautions. This helps in safe identification and handling.

Accessibility:
Store the compound in an area where it is accessible only to authorized personnel who are trained in its proper handling and storage.

Safety Data Sheets (SDS):
Maintain readily accessible Safety Data Sheets (SDS) for Disodium phosphate dihydrate in case of emergencies and for reference on safe handling and storage procedures.

Compatibility:
Familiarize yourself with the compatibility of Disodium phosphate dihydrate with storage materials, such as containers and seals, to prevent deterioration or contamination.

Regular Inspection:
Periodically inspect storage conditions to ensure that containers remain tightly sealed, and there are no signs of leakage or damage.

Waste Disposal:
Dispose of waste material, including empty containers, in compliance with local, state, and federal regulations governing the disposal of hazardous chemicals.



SYNONYMS


Sodium hydrogen phosphate dihydrate
Disodium hydrogen phosphate dihydrate
DSP dihydrate
Sodium phosphate dibasic dihydrate
Sodium phosphate, dibasic, dihydrate
Sodium hydrogenphosphate dihydrate
Disodium phosphate dihydrate
Disodium hydrogenphosphate dihydrate
Dibasic sodium phosphate dihydrate
Sodium phosphate, secondary, dihydrate
Sodium phosphate, secondary, dibasic, dihydrate
Sodium orthophosphate dihydrate
Disodium orthophosphate dihydrate
Dibasic sodium orthophosphate dihydrate
Disodium hydrogen orthophosphate dihydrate
Sodium phosphate (Na2HPO4) dihydrate
Sodium acid phosphate dihydrate
Secondary sodium phosphate dihydrate
Sodium monohydrogen phosphate dihydrate
Sodium orthophosphate dibasic dihydrate
Sodium phosphate, monobasic, dihydrate
Sodium hydrogen orthophosphate dihydrate
Sodium phosphate, monosodium, dihydrate
Sodium phosphate, monosodium, dibasic, dihydrate
Sodium hydrogen phosphate dibasic dihydrate
Sodium phosphate, bibasic, dihydrate
Sodium hydrogenphosphate dibasic dihydrate
Sodium phosphate, dihydrate, dibasic
Sodium hydrogen phosphate dibasic dihydrate
Sodium orthophosphate dibasic dihydrate
Sodium phosphate, secondary, dibasic, hydrate
Disodium orthophosphate dibasic dihydrate
Dibasic sodium hydrogen phosphate dihydrate
Disodium phosphate dibasic dihydrate
Dibasic sodium orthophosphate dibasic dihydrate
Sodium monohydrogen phosphate dibasic dihydrate
Sodium orthophosphate secondary dibasic dihydrate
Sodium phosphate, dihydrate, secondary, dibasic
Disodium hydrogen orthophosphate dibasic dihydrate
Sodium phosphate, monosodium, dibasic, dihydrate
Sodium dihydrogen phosphate dibasic dihydrate
Sodium phosphate, dibasic, secondary, dihydrate
Disodium phosphate, secondary, dibasic, dihydrate
Sodium monophosphate dibasic dihydrate
Sodium orthophosphate, dihydrate, secondary, dibasic
Dibasic sodium monophosphate dibasic dihydrate
Disodium dihydrogen phosphate dibasic dihydrate
Sodium phosphate, monosodium, secondary, dibasic, dihydrate
Sodium acid phosphate dibasic dihydrate
Disodium phosphate, secondary, secondary, dibasic, dihydrate
Sodium phosphate, bibasic, secondary, dihydrate
Sodium hydrogenphosphate secondary dibasic dihydrate
Sodium phosphate, dihydrate, secondary, secondary, dibasic
Sodium hydrogen phosphate secondary dibasic dihydrate
Sodium orthophosphate secondary dibasic dihydrate
Sodium phosphate, tertiary, dihydrate
Sodium hydrogenphosphate tertiary dihydrate
Sodium phosphate, dihydrate, tertiary
Sodium hydrogen phosphate tertiary dihydrate
Sodium orthophosphate tertiary dihydrate
Sodium phosphate, quaternary, dihydrate
Sodium hydrogenphosphate quaternary dihydrate
Sodium phosphate, dihydrate, quaternary
Sodium hydrogen phosphate quaternary dihydrate
Sodium orthophosphate quaternary dihydrate
Sodium phosphate, pentahydrate
Sodium hydrogenphosphate pentahydrate
Sodium phosphate, pentahydrate, dibasic
Sodium hydrogen phosphate pentahydrate
Sodium orthophosphate pentahydrate
Sodium phosphate, pentahydrate, dibasic, secondary
Sodium hydrogen phosphate pentahydrate, secondary
Sodium phosphate, dibasic, pentahydrate
Sodium hydrogen phosphate dibasic pentahydrate
Sodium orthophosphate dibasic pentahydrate
DISODIUM PHOSPHATE DODECAHYDRATE
Disodium phosphate dodecahydrate IUPAC Name disodium;hydrogen phosphate;dodecahydrate Disodium phosphate dodecahydrate InChI InChI=1S/2Na.H3O4P.12H2O/c;;1-5(2,3)4;;;;;;;;;;;;/h;;(H3,1,2,3,4);12*1H2/q2*+1;;;;;;;;;;;;;/p-2 Disodium phosphate dodecahydrate InChI Key DGLRDKLJZLEJCY-UHFFFAOYSA-L Disodium phosphate dodecahydrate Canonical SMILES O.O.O.O.O.O.O.O.O.O.O.O.OP(=O)([O-])[O-].[Na+].[Na+] Disodium phosphate dodecahydrate Molecular Formula H25Na2O16P Disodium phosphate dodecahydrate CAS 7632-05-5 (Parent) Disodium phosphate dodecahydrate ( European Community (EC) Number 600-088-6 Disodium phosphate dodecahydrate UNII E1W4N241FO Disodium phosphate dodecahydrate DSSTox Substance ID DTXSID4064923 Disodium phosphate dodecahydrate Property Name Property Value Reference Disodium phosphate dodecahydrate Molecular Weight 358.14 g/mol Disodium phosphate dodecahydrate Hydrogen Bond Donor Count 13 Disodium phosphate dodecahydrate Hydrogen Bond Acceptor Count 16 Disodium phosphate dodecahydrate Rotatable Bond Count 0 Disodium phosphate dodecahydrate Exact Mass 358.06756 g/mol Disodium phosphate dodecahydrate Monoisotopic Mass 358.06756 g/mol Disodium phosphate dodecahydrate Topological Polar Surface Area 95.4 Ų Disodium phosphate dodecahydrate Heavy Atom Count 19 Disodium phosphate dodecahydrate Formal Charge 0 Disodium phosphate dodecahydrate Complexity 46.5 Disodium phosphate dodecahydrate Isotope Atom Count 0 Disodium phosphate dodecahydrate Defined Atom Stereocenter Count 0 Disodium phosphate dodecahydrate Undefined Atom Stereocenter Count 0 Disodium phosphate dodecahydrate Defined Bond Stereocenter Count 0 Disodium phosphate dodecahydrate Undefined Bond Stereocenter Count 0 Disodium phosphate dodecahydrate Covalently-Bonded Unit Count 15 Disodium phosphate dodecahydrate Compound Is Canonicalized Yes Disodium phosphate dodecahydrate , also known as orthophosphoric acid or Disodium phosphate dodecahydrate , is a weak acid with the chemical formula H3PO4. It is normally encountered as a colorless syrup of 85% concentration in water. The pure compound is a colorless solid.All three hydrogens are acidic to varying degrees and can be lost from the molecule as H+ ions (protons). When all three H+ ions are removed, the result is an orthophosphate ion PO43−, commonly called "phosphate". Removal of one or two protons gives dihydrogen phosphate ion H2PO−4, and the hydrogen phosphate ion HPO2−4, respectively. Disodium phosphate dodecahydrate also forms esters, called organophosphates.Disodium phosphate dodecahydrate is commonly encountered in chemical laboratories as an 85% aqueous solution, which is a colourless, odourless, and non-volatile syrupy liquid. Although Disodium phosphate dodecahydrate does not meet the strict definition of a strong acid, the 85% solution can still severely irritate the skin and damage the eyes.The name "Disodium phosphate dodecahydrate " can be used to distinguish this specific acid from other "Disodium phosphate dodecahydrate ", such as pyrophosphoric acid. Nevertheless, the term "Disodium phosphate dodecahydrate " often means this specific compound; and that is the current IUPAC nomenclature.Disodium phosphate dodecahydrate is produced industrially by two general routes. In the wet process a phosphate-containing mineral such as calcium hydroxyapatite is treated with sulfuric acid.{\displaystyle {\ce {Ca5(PO4)3OH + 5H2SO4 -> 3H3PO4 + 5CaSO4v + H2O}}}{\displaystyle {\ce {Ca5(PO4)3OH + 5H2SO4 -> 3H3PO4 + 5CaSO4v + H2O}}} Fluoroapatite is an alternative feedstock, in which case fluoride is removed as the insoluble compound Na2SiF6. The Disodium phosphate dodecahydrate solution usually contains 23–33% P2O5 (32–46% H3PO4). It may be concentrated to produce commercial- or merchant-grade Disodium phosphate dodecahydrate , which contains about 54–62% P2O5 (75–85% H3PO4). Further removal of water yields Disodium phosphate dodecahydrate with a P2O5 concentration above 70% (corresponding to nearly 100% H3PO4). Calcium sulfate (gypsum) is produced as a by-product and is removed as phosphogypsum.To produce food-grade Disodium phosphate dodecahydrate , phosphate ore is first reduced with coke in an electric arc furnace, to make elemental phosphorus. Silica is also added, resulting in the production of calcium silicate slag. Elemental phosphorus is distilled out of the furnace and burned with air to produce high-purity phosphorus pentoxide, which is dissolved in water to make Disodium phosphate dodecahydrate .The Disodium phosphate dodecahydrate from both processes may be further purified by removing compounds of arsenic and other potentially toxic impurities.Food-grade Disodium phosphate dodecahydrate (additive E338) is used to acidify foods and beverages such as various colas and jams, providing a tangy or sour taste. Soft drinks containing Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat), which would include Coca-Cola, are sometimes called phosphate sodas or phosphates. Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) in soft drinks has the potential to cause dental erosion.Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) also has the potential to contribute to the formation of kidney stones, especially in those who have had kidney stones previously.Specific applications of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) include:In anti-rust treatment by phosphate conversion coating or passivation As an external standard for phosphorus-31 nuclear magnetic resonance.In Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) fuel cells.In activated carbon production.In compound semiconductor processing, to etch Indium gallium arsenide selectively with respect to indium phosphide.In microfabrication to etch silicon nitride selectively with respect to silicon dioxide.As a pH adjuster in cosmetics and skin-care products.As a sanitizing agent in the dairy, food, and brewing industries.A link has been shown between long-term regular cola intake and osteoporosis in later middle age in women (but not men).This was thought to be due to the presence of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat), and the risk for women was found to be greater for sugared and caffeinated colas than diet and decaffeinated variants, with a higher intake of cola correlating with lower bone density.At moderate concentrations Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) solutions are irritating to the skin. Contact with concentrated solutions can cause severe skin burns and permanent eye damage.Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) is a unique inorganic acid electrolyte, which is generally used in fuel cell applications at around 200 °C in order to obtain higher system efficiency where its concentration is over 100%. A matrix, which is made of SiC, is used to retain the hot Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) in a cell. Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) has advantageous properties as an electrolyte, such as low volatility, good ionic conductivity, stability at relatively high temperatures, carbon dioxide tolerance, and also carbon monoxide tolerance. With all these advantages, there have been several technical electrolyte-related problems with fuel cell stacks. The major issues are volume change, evaporation loss, and electrolyte migration, and these are described in detail. These problems mainly arise due to the fact that Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) is a liquid electrolyte under fuel cell operation.Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) (H3PO4, also known as Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) or phosphoric (V) acid) is a mineral inorganic acid. Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) refers to Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) in which the prefix ortho is used to distinguish the acid from related Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat), called polyphosphoric acids. Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat), when pure, is a solid at room temperature and pressure. The most common source of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) is an 85% aqueous solution that is colorless and nonvolatile but is sufficiently acidic to be corrosive. Because of the high percentage of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) in this reagent, at least some of the Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) is condensed into Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat). For the sake of labeling and simplicity, the 85% represents the acid as if it was all Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat). Dilute aqueous solutions of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) exist in the orthoform.Phosphoric acid (H3PO4) can be manufactured using either a thermal or a wet process. However, the majority of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) is produced using the wet-process method. Wet-process Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) is used for fertilizer production. Thermal process Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) is commonly used in the manufacture of high-grade chemicals, which require a much higher purity. The production of wet-process Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) generates a considerable quantity of acidic cooling water with high concentrations of phosphorus and fluoride. This excess water is collected in cooling ponds that are used to temporarily store excess precipitation for subsequent evaporation and to allow recirculation of the process water to the plant for reuse.In the wet process, Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) is produced by reacting sulfuric acid (H2SO4) with naturally occurring phosphate rock. The phosphate rock is dried, crushed, and then continuously fed into the reactor along with sulfuric acid. The reaction combines calcium from the phosphate rock with sulfate, forming calcium sulfate (gypsum, CaSO4), which is separated from the reaction solution by filtration. Some facilities generally use a dihydrate process that produces gypsum in the form of calcium sulfate with two molecules of water (calcium sulfate dihydrate, CaSO4·2H2O). Other facilities may use a hemihydrate process that produces calcium sulfate with the equivalent of a half molecule of water per molecular of calcium sulfate (2CaSO4·H2O). The one-step hemihydrate process has the advantage of producing wet-process Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) with a higher concentration of phosphorus pentoxide (P2O5) and less impurities than the dihydrate process. A simplified reaction for the dihydrate process is as follows:In order to make the strongest pDisodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) possible and to decrease evaporation costs, 93% (v/v) sulfuric acid is normally used. During the reaction, gypsum crystals are precipitated and separated from the acid by filtration. The separated crystals must be washed thoroughly to yield at least a 99% (v/v) recovery of the filtered Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat). After washing, the slurried gypsum is pumped into a gypsum pond for storage. Water is siphoned off and recycled through a surge cooling pond to the Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) process. Wet-process Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) normally contains 26%–30% (w/w) phosphorus pentoxide, and in most cases, the acid must be further concentrated to meet phosphate feed material specifications for fertilizer production. Depending on the types of fertilizer to be produced, Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) is usually concentrated to 40%–55% (w/w) phosphorus pentoxide by using two or three vacuum evaporators.In the thermal process, the raw materials for the production of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) are elemental (yellow) phosphorus, air, and water. The process involves three major steps: (1) combustion, (2) hydration, and (3) demisting. In the combustion step, the liquid elemental phosphorus is burned (oxidized) in ambient air in a combustion chamber at temperatures of 1650–2760°C (3000–5000°F) to form phosphorus pentoxide:The phosphorus pentoxide is then hydrated with dilute phosphoric acid (H3PO4) or water to produce strong Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) liquid.The final step is a demisting step that is applied to removal of the Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) mist from the combustion gas stream before releasing to the atmosphere, which is usually accomplished by use of high-pressure-drop demisters. As always, release to the atmosphere can only be accomplished if the demisted product is a clean and nonpolluting stream.The concentration of phosphoric acid (H3PO4) produced from the thermal process normally ranges from 75% to 85% (v/v). This concentration is required for high-grade chemical production and other nonfertilizer product manufacturing. Efficient plants recover approximately 99.9% (w/w) of the elemental phosphorus burned as the phosphoric acid product.In Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) production, the fluorine released from reactors and evaporators is usually recovered as a by-product that can be sold. The remainder is passed to the condenser that produces a liquid effluent with mostly fluoride and small amounts of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat). Closed systems recycle this effluent; in other cases, it is discharged to open waters.The manufacture of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) produces a gypsum slurry that is sent to settling ponds to allow the solids to settle out. About 5 lbs of phosphor-gypsum is generated per pound of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat). This phosphor-gypsum contains trace elements from phosphate rock, such as cadmium and uranium. Pond systems are usually fitted with lining systems and collection ditches to maintain control of trace elements and avoid contamination of ground water.The major source of phosphorus in the world is apatite, which is a group of phosphate minerals, usually referring to hydroxylapatite, fluorapatite and chlorapatite, with high concentrations of hydroxyl (OH−) ions, fluoride (F−) ions, and chloride (Cl−) ions, respectively, in the crystal apatite (Ca5(PO4)3(F,Cl,OH)). Commercially, the most important is fluoroapatite, a calcium phosphate that contains fluorine. This fluorine must be removed for the manufacture of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat), but it also can be used to produce hydrofluoric acid and fluorinated compounds.Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) esters, for example, tributyl phosphate, (CH3CH2CH2CH2O)3PO are used for the separation of nuclear fuel elements, uranium, zirconium and hafnium, and rare earth elements. Trioctyl phosphine oxide (TOPO), R3PO where R is C8H17) is another solvationg extractant used to recover uranium from wet process Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) liquors (Hudson, 1982). It is also used as a constituent of supported liquid membranes to recover rhenium from hydrometallurgical effluents (to be described in Chapter 12). Some long chain ketones, for example, methyl isobutyl ketone, CH3CO,CH2CH(CH3)2 have been used for separation of niobium and tantalum (described in Chapter 10).Conductivity An increase in Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) doping levels results in a clear increase in membrane conductivity related to the increase in proton ‘carriers’. Thus at 150 °C, for doping levels of 4.7, 6.7, and 14.5 Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) moles per PBI repeat unit, respective conductivities of 18, 22, and 79 mS cm−1 were obtained. On the contrary, it was observed that membrane conductivities increase up to 150 °C and then decline. This behavior was attributed to the self-dehydration of Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) above 150 °C, resulting in less conductive pyrophosphoric acid.At a doping level corresponding to the maximum protonation of PBI, i.e., two Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) moles per PBI repeat unit, the proton hopping from N site to the Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) anion was reported to contribute significantly to conductivity, which reached 25 mS cm−1 at 200 °C.On the contrary, at an acid doping level of 5.6 Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) moles per PBI repeat unit, ‘free acid’ contribution to conductivity is dominant. The conductivity of PBI was found to improve with atmospheric humidity, but its dependence on RH was far less than in Nafion membranes. This hopping-like mechanism is confirmed by Arrhenius behavior of conductivity.Hydration, too, releases some additional heat. The properties of phosphorus pentoxide and the absorption process inevitably leave as much as 25% of the oxide plus a Disodium phosphate dodecahydrate (Disodyum fosfat dodekahidrat) mist in the exit gases from the absorption tower. These are captured on passage through an electrostatic precipitator. By variations of the process details and equipment, grades (concentrations) of phosphoric acid from 75–105% (ortho, or superphosphoric acid) H3PO4 may be made in this manner.Phosphoric acid production by phosphorus combustion is usually accomplished in a stepwise manner as outlined, with intermediate isolation of the phosphorus. However, it may also be made by direct contact of phosphorus vapor from the furnace of a phosphorus plant with an air stream, and then passing the phosphorus pentoxide produced directly into a hydrator, without collection of the intermediate phosphorus as a liquid. Direct conversion to phosphoric acid in this way is attractive because the bulk of white phosphorus produced is converted to phosphoric acid.What is Phosphoric Acid? Phosphoric acid is a colorless, odorless mineral acid. With an acidic taste and somewhat viscous consistency, phosphoric acid is used in a wide variety of products and industries. Despite its popularity, this chemical can pose some potentially significant health hazards and should be handled with caution.Common Uses of Phosphoric Acid Phosphoric acid is used in several industries. Fertilizer accounts for the majority of phosphoric acid use, but this chemical can also be found in:Food additives (to acidify foods, or as a leavening agent) Soaps and detergents Water treatment Toothpastes Rust removal Etching solutions in dentistry Teeth whiteners Cleaning products Health Hazards Associated with Phosphoric Acid Phosphoric acid can be very hazardous in the case of skin contact, eye contact, and ingestion. It can also cause irritation if vapors are inhaled. This chemical can cause damage to the skin, eyes, mouth, and respiratory tract. Because of the potential hazards posed by this chemical, it is important to use care when handling it.Repeated or prolonged exposure to phosphoric acid mist can lead to chronic eye irritation, severe skin irritation, or prolonged respiratory tract issues. To protect your health when handling this potentially hazardous chemical, it is important to use caution in the form of personal protective equipment (PPE).Phosphoric Acid Safety, Handling & First Aid When handing phosphoric acid, use a certified vapor respirator. Eye-wash stations and safety showers should be located near work stations as a precaution. A face shield, gloves and boots should also be used. In case of accidental exposure to phosphoric acid, follow these first aid guidelines:Inhalation—Seek fresh air and immediate medical attention.Eye Contact—Remove contact lenses if present. Immediately flush eyes with plenty of water for at least 15 minutes, and get medical attention.Skin Contact—Wash skin with soap and water. Cover any irritated skin with an emollient. Seek medical attention.Ingestion—Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Seek medical attention if any adverse health symptoms occur.Safe Storage & Disposal of Phosphoric Acid Store phosphoric acid in a cool, well-ventilated area protected from moisture. Keep away from incompatible substances such as oxidizing agents, metals, combustible materials, and alkalis. This chemical should be stored in a metallic or coated fiberboard container using a strong polyethylene inner package. Dispose of this chemical in accordance with federal, state, and local environmental control regulations.Need more safety information about phosphoric acid or other chemicals in your workplace? Check out our extensive library of MSDS information here.Phosphoric Acid can affect you when breathed in.Phosphoric Acid is a CORROSIVE CHEMICAL and contact can irritate and burn the eyes.Breathing Phosphoric Acid can irritate the nose, throat and lungs causing coughing and wheezing.Long-term exposure to the liquid may cause drying and cracking of the skin.IDENTIFICATION Phosphoric Acid is a colorless, odorless solid or a thick, clear liquid. It is used in rustproofing metals, fertilizers, detergents,foods, beverages, and water treatment.Acute Health Effects The following acute (short-term) health effects may occur immediately or shortly after exposure to Phosphoric Acid:Contact can irritate and burn the eyes.Breathing Phosphoric Acid can irritate the nose and throat causing coughing and wheezing.Chronic Health Effects The following chronic (long-term) health effects can occur at some time after exposure to Phosphoric Acid and can last for months or years:Cancer Hazard Phosphoric Acid has not been tested for its ability to cause cancer in animals.Reproductive Hazard Phosphoric Acid has not been tested for its ability to affect reproduction.Other Long-Term Effects Phosphoric Acid can irritate the lungs. Repeated exposure may cause bronchitis to develop with cough, phlegm and/or shortness of breath.Long-term exposure to the liquid may cause drying and cracking of the skin.Where possible, automatically transfer solid Phosphoric Acid or pump liquid Phosphoric Acid from drums or other storage containers to process containers.Workers whose clothing has been contaminated by Phosphoric Acid should change into clean clothing promptly.Do not take contaminated work clothes home. Family members could be exposed.Contaminated work clothes should be laundered by individuals who have been informed of the hazards of exposure to Phosphoric Acid.Eye wash fountains should be provided in the immediate work area for emergency use.If there is the possibility of skin exposure, emergency shower facilities should be provided.On skin contact with Phosphoric Acid, immediately wash or shower to remove the chemical. At the end of the workshift, wash any areas of the body that may have contacted Phosphoric Acid, whether or not known skin contact has occurred.Do not eat, smoke, or drink where Phosphoric Acid is handled, processed, or stored, since the chemical can be swallowed. Wash hands carefully before eating, drinking,smoking, or using the toilet.For solid Phosphoric Acid, use a vacuum to reduce dust during clean-up. DO NOT DRY SWEEP.Clothing Avoid skin contact with Phosphoric Acid. Wear acidresistant gloves and clothing. Safety equipment suppliers/manufacturers can provide recommendations on the most protective glove/clothing material for your operation.All protective clothing (suits, gloves, footwear, headgear) should be clean, available each day, and put on before work.Safety equipment manufacturers recommend Natural Rubber, Nitrile Rubber, Polyvinyl Chloride, Viton or Neoprene as protective materials.SPILLS AND EMERGENCIES If Phosphoric Acid is spilled or leaked, take the following steps:Evacuate persons not wearing protective equipment from area of spill or leak until clean-up is complete.Cover liquids with dry lime, sand or soda ash, and place in covered containers for disposal.Collect powdered material in the most convenient manner and deposit in sealed containers.Ventilate and wash area after clean-up is complete.It may be necessary to contain and dispose of Phosphoric Acid as a HAZARDOUS WASTE.If employees are required to clean-up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable.Prior to working with Phosphoric Acid you should be trained on its proper handling and storage.Phosphoric Acid will react with FINELY POWDERED METALS to form flammable and explosive Hydrogen gas.Phosphoric Acid must be stored to avoid contact with WATER; AMMONIA; BLEACH; and NITROMETHANE since violent reactions occur.Phosphoric Acid is not compatible with STRONG BASES (such as SODIUM HYDROXIDE and POTASSIUM HYDROXIDE); COMBUSTIBLES; ORGANICS;ALCOHOLS; STRONG ACIDS (such as HYDROCHLORIC, SULFURIC and NITRIC); AMINES;EPOXIDES; METALS; and METAL SALTS.Store in tightly closed containers in a cool, well-ventilated area away from GLASS, RUBBER, PLASTICS and COATINGS.The USP 32 states that dibasic sodium phosphate is dried or contains, 1, 2, 7, or 12 molecules of water of hydration. Anhydrous dibasic sodium phosphate occurs as a white powder. The dihydrate occurs as white or almost white, odorless crystals.The heptahydrate occurs as colorless crystals or as a white granular or caked salt that effloresces in warm, dry air. The dodecahydrate occurs as strongly efflorescent, colorless or transparent crystals.Either bone phosphate (bone ash), obtained by heating bones to whiteness, or the mineral phosphorite is used as a source of tribasic calcium phosphate, which is the starting material in the industrial production of dibasic sodium phosphate.Tribasic calcium phosphate is finely ground and digested with sulfuric acid. This mixture is then leached with hot water and neutralized with sodium carbonate, and dibasic sodium phosphate is crystallized from the filtrate.Dibasic sodium phosphate is used in a wide variety of pharmaceutical formulations as a buffering agent and as a sequestering agent. Therapeutically, dibasic sodium phosphate is used as a mild laxative and in the treatment of hypophosphatemia.Dibasic sodium phosphate is also used in food products; for example as an emulsifier in processed cheese.Dibasic sodium phosphate is widely used as an excipient in parenteral, oral, and topical pharmaceutical formulations. Phosphate occurs extensively in the body and is involved in many physiological processes since it is the principal anion of intracellular fluid. Most foods contain adequate amounts of phosphate, making hypophosphatemia (phosphate deficiency) virtually unknown except for certain disease states or in patients receiving total parenteral nutrition. Treatment is usually by the oral administration of up to 100 mmol of phosphate daily.Approximately two-thirds of ingested phosphate is absorbed from the gastrointestinal tract, virtually all of it being excreted in the urine, and the remainder is excreted in the feces.Excessive administration of phosphate, particularly intravenously, rectally, or in patients with renal failure, can cause hyperphosphatemia that may lead to hypocalcemia or other severe electrolyte imbalances. Adverse effects occur less frequently following oral consumption, although phosphates act as mild saline laxatives when administered orally or rectally. Consequently, gastrointestinal disturbances including diarrhea, nausea, and vomiting may occur following the use of dibasic sodium phosphate as an excipient in oral formulations. However, the level of dibasic sodium phosphate used as an excipient in a pharmaceutical formulation is not usually associated with adverse effects.LD50 (rat, oral): 17 g/kgThe anhydrous form of dibasic sodium phosphate is hygroscopic. When heated to 40℃, the dodecahydrate fuses; at 100℃ it loses its water of crystallization; and at a dull-red heat (about 240℃) it is converted into the pyrophosphate, Na4P2O7. Aqueous solutions of dibasic sodium phosphate are stable and may be sterilized by autoclaving.The bulk material should be stored in an airtight container, in a cool, dry place.Sodium Phosphate Dibasic Dodecahydrate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement.Disodium Phosphate Dodecahydrate is white or colorless crystalline free flowing solid, efflorescent in air, easily soluble in water, but insoluble in alcohol, its water solution is slightly alkaline, relative density at 1.52 g/cm3, melting point at 35℃.Disodium Phosphate Dodecahydrate is used as water softening agent for boiler, buffering agent, solder, tanning agent, etc.Disodium phosphate is used in conjunction with trisodium phosphate in many steam-boiler applications. It supplies the inventory of free phosphates to retard calcium scale formation. In water treatment, Disodium Phosphate retards calcium scale formation.Disodium Phosphate is used for boiler soft agent, fabric, wood and paper of flame retardants, glaze medicine. Disodium Phosphate is also found in some detergents and cleaning agents, and dyeing with salt.In printing and dyeing industries, Disodium phosphate used as hydrogen peroxide bleaching stabilizer, rayon packing (enhancement of silk strength and elastic), and for manufacturing focal phosphorus sodium and other raw materials, as well as monosodium glutamate, erythromycin, penicillin, streptomycin, and sewage production, cultivating agent products etc.It also used in electroplating, leather.Packing:In PP+PE bags of 25kgs net each, we can provide packages according to customer’s requirement .Storage: Store at a cool, dry and well ventilated place.Shelf life: 24 months.Support: Disodium Phosphate Dodecahydrate – Material Safety Data Sheet (MSDS).Sodium Phosphate Dibasic, Dodecahydrate, also known as Disodium hydrogen phosphate, can be is used to adjust pH or as an anti-caking additive in powdered products. It is an electrolyte replenisher and with radio-protective activity.Disodium phosphate dodecahydrate contains not less than 98.0 per cent and not more than the equivalent of 101.0 percent of Na2HPO4, calculated with reference to the anhydrous substance.Colourless, transparent crystals, very efflorescent, very soluble in water, practically insoluble in ethanol (96 percent).Our range of products include di sodium hydrogen phosphate dodecahydrate ip, di sodium hydrogen phosphate dodecahydrate bp, di sodium hydrogen phosphate dodecahydrate pure, di sodium hydrogen phosphate dodecahydrate usp, di sodium hydrogen phosphate dodecahydrate acs and di sodium hydrogen phosphate dodecahydrate food grade.Disodium hydrogen phosphate is a sodium salt of phosphoric acid. It is a white/crystaline powder that is highly hygroscopic and water soluble. It is therefore used commercially as an anti-caking additive in powdered products. Disodium phosphate is used in Cream of Wheat to quicken cook time, as described on the ingredients panel of the product package, antioxidant, emulsifier & food additives.Disodium hydrogen phosphate is a sodium salt of phosphoric acid. It is a white/crystaline powder that is highly hygroscopic and water soluble. It is therefore used commercially as an anti-caking additive in powdered products. Disodium phosphate is used in Cream of Wheat to quicken cook time, as described on the ingredients panel of the product package, antioxidant, emulsifier & food additives.Disodium hydrogen phosphate is a sodium salt of phosphoric acid.
DISODIUM PYROPHOSPHATE
Disodium pyrophosphate, also known as Sodium acid pyrophosphate, is a white, water soluble solid that has many applications in the food industry.
Disodium pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.
Disodium pyrophosphate is a popular leavening agent found in baking powders.

CAS Number: 7758-16-9
EC Number: 231-835-0
Molecular Formula: H5NaO7P2
Molcular Weight: 201.97

Disodium dihydrogen diphosphate, Diphosphoric acid, disodium salt, Disodium dihydrogen pyrophosphate, Disodium diphosphate, Sodium acid pyrophosphate, SAPP, Disodium Pyrophosphate, Disodium Diphosphate, Disodium Dihydrogen Diphosphate, Disodium Dihydrogen Pyrophosphate, Diphosphoric Acid, Disodium Salt, Pyrophosphoric Acid, Disodium Salt, Disodium diphosphate, Disodium pytophosphate, Disodium dihydroge3 disodium salt, H5WVD9LZUD, Sodium pyrophosphate (Na2H2P2O7), Diphosphoric acid, sodium salt (1:2), Dinatriumpyrophosphat, Sodium polyphosphates, Natrium polyphosphat, Sodium polyphosphatium phosphate, Natrium polyphosphatium DS42_Sodium Polyphosphate dihydrogendiphosphate, DSSTox_RID_78658, DSSTox_GSID_28842 ,2Na.H2P2O7, Sodium dihydrogen pyrophosphate, Sodium polyphosphate, amorphous, CHEMBL3184949, DTXSID_GSID_28842, LS-2432, NCGC00258367-01, [hydroxy(oxido)phosphoryl] hydrogen phosphate, Sodium acid pyrophosphate, SAPP, Diphosphoric acid, disodium salt, Disodium acid pyrophosphate, Disodium dihydrogen diphosphate, Disodium dihydrogen pyrophosphate, Disodium diphosphate, Pyrophosphoric acid, disodium salt, Sodium pyrophosphate dibasic, disodium dihydrogen pyrophosphate, pyrophosphoric acid, disodium salt (8ci), sapp 40, disodiumdiphosphate, sapp, sodium acid pyrophosphate(sapp), sodium acid pyrophosphate (sapp), dspp, dihydrogen disodium pyrophosphate, disodium pyrophosphate (na2h2p2o7), sodiumpyrophosphate,acid, dinatriumpyrophosphat, disodium pytophospha, disodium pyrophosphate, disodium dihydrogen diphosphate, disodium pytophosphate, diphosphoricacid, disodium salt (9ci), sodiumpyrophosphate (na2h2p2o7) (6ci), sapp 28, sapp-rd 1, disodium dihydrogendiphosphate (na2h2p2o7), sodium hydrogen phosphate (na2h2p2o7), Disodium dihydrogen pyrophosphate, SAPP, E450, 7758-16-9, Disodium diphosphate, Sodium acid pyrophosphate, Disodium dihydrogen pyrophosphate, DISODIUM PYROPHOSPHATE, H5WVD9LZUD, disodium;[hydroxy(oxido)phosphoryl] hydrogen phosphate, MFCD00014246, Disodium acid pyrophosphate, Dinatriumpyrophosphat, Disodiumpytophosphate, Dinatriumpyrophosphat [German], Disodium dihydrogen diphosphate, Disodium dihydrogenpyrophosphate, HSDB 377, Pyrophosphoric acid, disodium salt, UNII-H5WVD9LZUD, Sodium pyrophosphate (Na2H2P2O7), EINECS 231-835-0, Sodium diphosphate dibasic, disodium hydrogen (hydrogen phosphonatooxy)phosphonate, Grahamsches salz, Glassy sodium phosphate, DSSTox_CID_8842, sodium dihydrogendiphosphate, EC 231-835-0, DSSTox_RID_78658, DSSTox_GSID_28842, SODIUMACIDPYROPHOSPHATE, Sodium pyrophosphate, dibasic, Sodium dihydrogen pyrophosphate, CHEMBL3184949, EINECS 272-808-3, Tox21_200813, DISODIUM PYROPHOSPHATE [HSDB], DISODIUM PYROPHOSPHATE [INCI], DISODIUM PYROPHOSPHATE [VANDF], AKOS015916169, AKOS024418779, SODIUM ACID PYROPHOSPHATE [MI], Diphosphoric acid, sodium salt (1:2), SODIUM ACID PYROPHOSPHATE [FCC], NCGC00258367-01, SODIUM ACID PYROPHOSPHATE [VANDF], CAS-68915-31-1

Disodium pyrophosphate is a food-grade chemical compound that belongs to the group of sodium phosphates.
Disodium pyrophosphate is a white, crystalline powder or granular material with various applications in the food industry.

Disodium pyrophosphate is recognized as a food additive and is commonly used for its leavening, buffering, and emulsifying properties.
Disodium pyrophosphate serves as a buffering, chelating and leavening agent.

Disodium pyrophosphate encodes a integral membrane protein.
Disodium pyrophosphate is a soluble protein generated by sequential cleavage with α and γ secretase.

Disodium pyrophosphate, also known as Sodium acid pyrophosphate, is an inorganic compound composed of sodium cation and pyrophosphate anion.
Disodium pyrophosphate is a white, water-soluble solid, commonly used as a buffer and chelating agent and has many applications in food processing industry.

Disodium pyrophosphate is a white monoclinic crystal powder.
Disodium pyrophosphates relative density is 1.86.

Disodium pyrophosphate is soluble in water, insoluble in alcohol.
Disodium pyrophosphate hydrolyzes to orthophosphate when heated in acid medium.

Disodium pyrophosphate is hygroscopic, forms hexahydrate in damp air, and decomposes to metaphosphate at above 220℃.
The leavening acid, Disodium pyrophosphate is an important component of double acting baking powder as well as self rising flour.

Disodium pyrophosphate reacts in stages and is desirable in baking applications for its slow action.
Disodium pyrophosphate or Sodium acid pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.

Disodium pyrophosphate is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.
When crystallized from water, Disodium pyrophosphate forms a hexahydrate, but Disodium pyrophosphate dehydrates above room temperature.

Disodium pyrophosphate is a polyvalent anion with a high affinity for polyvalent cations.
Disodium pyrophosphate, also known as disodium dihydrogen pyrophosphate, Sodium acid pyrophosphate, is white crystalline powder, which has the relative density of 1.864 and can decompose into sodium metaphosphate when Disodium pyrophosphate is heated above 220℃.

Disodium pyrophosphate is easily soluble in water and can form chelates with Cu2+ and Fe2+.
The aqueous solution can be hydrolyzed to phosphoric acid by heating with dilute sulfuric acid or dilute mineral acid.

Disodium pyrophosphate is usually used in food processing industry.
Disodium pyrophosphate, or disodium dihydrogen pyrophosphate, its food grade is commonly used with sodium bicarbonate as a leavening agent in bakery products; also, Disodium pyrophosphate maintains the color in processed potatoes and also prevents struvite crystal in canned seafood.

The European food additive number for Disodium pyrophosphate is E450(i).
Generally, Disodium pyrophosphate is vegan and gluten free.

Disodium pyrophosphate also known as Di-sodium Di-phosphate is an inorganic compound of sodium and pyrophosphate.
Disodium pyrophosphate is white and soluble in water.

Disodium pyrophosphate is manufactured with double drying process like other Pyrophosphates due to heating needed at a high temperature.
Disodium pyrophosphate is solubility in water is 13g Na2H2P2O7/100g H2O at 20 °C, and 20g at 80°C.

The pH of a 1% aqueous solution is 4.1. The usual commercial product is the anhydrous, nonhygroscopic salt in powder form.
The hexahydrate, Na2H2P2O7.6H2O, d 1.85, crystallizes from aqueous solution below 27 °C.

Above this temperature, Disodium pyrophosphate is converted to the anhydrous form.
Disodium pyrophosphate is used as a (tropically stable) acid carrier in baking powder, for improvement of flow properties in flour, for pH regulation, and in dental care products for prevention of tartar formation.

Disodium pyrophosphate is available in a variety of grades that affect the speed of its action.
Because the resulting phosphate residue has an off-taste, Disodium pyrophosphate is usually used in very sweet cakes which mask the off-taste.

Disodium pyrophosphate is manufactured by partially neutralizing food grade phosphoric acid with sodium hydroxide or sodium carbonate to form monosodium phosphate.
Dehydration of monosodium phosphate at 250°C will form Disodium pyrophosphate.

Leavening acids provide air and volume to the baked good structure, but also affect the characteristics of the dough.
Besides reacting with baking soda to produce the gas carbon dioxide, these acids form ionic bonds with the starches and proteins in the dough.

Disodium pyrophosphate dissolves readily to form the anion pyrophosphate which interacts with the proteins in a baked good system to provide a moist texture.
Also, Disodium pyrophosphate provides a buffer system for the dough in the pH range 7.3-7.5, which influences the color of the baked product.

Disodium pyrophosphate is a white, crystalline powder or granular substance.
Disodium pyrophosphate is a sodium salt of pyrophosphoric acid and is commonly used as a food additive and in various industrial applications.

Disodium pyrophosphate has unique chemical properties that make Disodium pyrophosphate versatile in different processes.
Disodium pyrophosphate acts as a leavening agent in food production, helping dough rise and creating a light texture in baked goods.
In addition to its culinary uses, Disodium pyrophosphate is utilized as a buffering agent, stabilizer, and emulsifier in food processing.

Disodium pyrophosphate also finds application as a corrosion inhibitor, pH adjuster, and chelating agent in various industries.
Disodium pyrophosphate is a slow leavening acid and Disodium pyrophosphate may contain a suitable aluminum and/or calcium salt to control the rate of reaction.
Disodium pyrophosphate and other sodium and potassium polyphosphates are widely used in food processing; in the E number scheme, they are collectively designated as E450, with the disodium form designated as E450(a).

In the United States, Disodium pyrophosphate is classified as generally recognized as safe (GRAS) for food use.
In canned seafood, Disodium pyrophosphate is used to maintain color and reduce purge[clarification needed] during retorting.
Retorting achieves microbial stability with heat.

Disodium pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.
In baking powder, Disodium pyrophosphate is often labeled as food additive E450.
In cured meats, Disodium pyrophosphate speeds the conversion of sodium nitrite to nitrite (NO2−) by forming the nitrous acid (HONO) intermediate,[clarification needed] and can improve water-holding capacity.

Disodium pyrophosphate is also found in frozen hash browns and other potato products, where Disodium pyrophosphate is used to keep the color of the potatoes from darkening.
Disodium pyrophosphate can leave a slightly bitter aftertaste in some products, but "the SAPP taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings."

Disodium pyrophosphate has limited direct uses in water treatment processes.
Disodium pyrophosphate can indirectly contribute to certain aspects of water treatment.

Disodium pyrophosphate is sometimes employed as a pH adjuster and buffering agent in water treatment applications where precise pH control is necessary.
Disodium pyrophosphate can help stabilize and maintain the desired pH range, optimizing treatment processes.

Disodium pyrophosphate can act as a sequestering agent, chelating metal ions and preventing their precipitation or interference with water treatment chemicals.
Its ability to bind with metal ions aids in minimizing scaling and maintaining the efficiency of water treatment equipment.

Disodium pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.
Disodium pyrophosphate is a white, water-soluble that serves as a buffering and chelating agent, with many applications in the food industry.

When crystallised from water, Disodium pyrophosphate forms hexahydrate, but Disodium pyrophosphate dehydrates above room temperature.
Disodium pyrophosphate is a polyvalent anion with a high affinity for polyvalent cations.

Disodium pyrophosphate is a popular leavening agent found in baking powders.
Disodium pyrophosphate combines with sodium bicarbonate to release carbon dioxide.

Disodium pyrophosphate is available in a variety of grades that effect the speed of its action.
Because the resulting phosphate residue has an off-taste, Disodium pyrophosphate is usually used in very sweet cakes which mask the taste.

Disodium pyrophosphate is designated in the USA as generally recognized as safe for food use.
Disodium pyrophosphate is used in canned seafood to maintain color and reduce purge during retorting.

Retorting achieves microbial stability with heat.
Disodium pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.

Disodium pyrophosphate is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Disodium pyrophosphate.
Disodium pyrophosphate is used as an acidulant, buffering agent, and leavening agent.
Disodium pyrophosphate has a dough reaction rate of 24 – 28.

Disodium pyrophosphate is an all-purpose phosphate commonly used in prepared mixes, commercial baking powders, and cake doughnut mixes.
Disodium pyrophosphate and other sodium and potassium polyphosphates are widely used in food processing; in the E number scheme, they are collectively designated as E450, with the disodium form designated as E450(a).

In the United States, Disodium pyrophosphate is classified as generally recognized as safe (GRAS) for food use.
In canned seafood, Disodium pyrophosphate is used to maintain color and reduce purge[clarification needed] during retorting.

Retorting achieves microbial stability with heat.
Disodium pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.

In baking powder, Disodium pyrophosphate is often labeled as food additive E450.
In cured meats, Disodium pyrophosphate speeds the conversion of sodium nitrite to nitrite (NO2−) by forming the nitrous acid (HONO) intermediate,[clarification needed] and can improve water-holding capacity.

Disodium pyrophosphate is also found in frozen hash browns and other potato products, where Disodium pyrophosphate is used to keep the color of the potatoes from darkening.
Disodium pyrophosphate can leave a slightly bitter aftertaste in some products, but "the SAPP taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings.
Disodium pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.

As a leavening acid which combines with baking soda to release carbon dioxide to improve the texture and volume of baked goods.
As a chelating agent to chelate iron to prevent discoloration in processed potato.
Amyloid precursor protein α is an α-secretase-cleaved soluble protein that has been shown to have neuroprotective properties.

Disodium pyrophosphate is derived from amyloid precursor protein.
The protein consists of 612 amino acids.
Several G protein-coupled receptors are known to activate α-secretase-dependent processing of APP.

Disodium pyrophosphate has neuroprotective, neurogenic and neurotrophic functions.
Amyloid precursor protein a also stimulates gene expression and protein expression.
In leather treatment, Disodium pyrophosphate can be used to remove iron stains on hides during processing.

Disodium pyrophosphate can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.
When added to scalding water, Disodium pyrophosphate facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.
Disodium pyrophosphate in petroleum production, Disodium pyrophosphate can be used as a dispersant in oil well drilling muds.

Disodium pyrophosphate can also be found in frozen hash browns and other potato products, where Disodium pyrophosphate is used to keep the color of the potatoes from darkening.
Disodium pyrophosphate is a sodium salt of pyrophosphoric acid, and its chemical formula is Na2H2P2O7.

Disodium pyrophosphate in the food industry is as a leavening agent.
Disodium pyrophosphate releases carbon dioxide gas when Disodium pyrophosphate reacts with alkalis, such as baking soda (sodium bicarbonate), when exposed to moisture and heat.

This gas production causes dough or batter to rise, resulting in baked goods with a lighter texture.
Disodium pyrophosphate is often used in baking powder formulations to provide a delayed or slow-acting leavening effect.

Disodium pyrophosphate acts as a pH buffer in various food products, helping to control and stabilize their acidity or alkalinity.
Disodium pyrophosphate is used in processed foods to maintain the desired pH level, preventing changes in flavor, color, and texture.

Disodium pyrophosphate can also serve as an emulsifying agent in certain food products, helping to blend ingredients that would not naturally mix together, such as oil and water.
Disodium pyrophosphate is commonly used in a variety of food products, including baked goods like cakes, muffins, and pancakes, as well as in pancakes, waffles, and other batter-based items.

Disodium pyrophosphate is also used in certain dairy products, such as processed cheeses, to help improve their melting and texture.
Disodium pyrophosphate may be used in meat products as a pH regulator, in canned seafood to maintain product quality, and in potato products like French fries to prevent discoloration.

Uses of Disodium pyrophosphate:
Disodium pyrophosphate is used Buffering Agents, Food & Beverage, Food Additives, Levelling Agents, Oil Field Services, Chelants, and Leather.

Food uses:
Disodium pyrophosphate is a popular leavening agent found in baking powders.

Disodium pyrophosphate combines with sodium bicarbonate to release carbon dioxide:
Na2H2P2O7 + NaHCO3 → Na3HP2O7 + CO2 + H2O

Disodium pyrophosphate is available in a variety of grades that affect the speed of its action.
Because the resulting phosphate residue has an off-taste, Disodium pyrophosphate is usually used in very sweet cakes which mask the off-taste.

Disodium pyrophosphate used as buffering agent, leavening agent, sequestrant agent.
Disodium pyrophosphate can be used in canned food, ham, meat,baking powder and so on.

Disodium pyrophosphate in baking powder, New Zealand, 1950s
Disodium pyrophosphate and other sodium and potassium polyphosphates are widely used in food processing.

In canned seafood, Disodium pyrophosphate is used to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.

Disodium pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.
Disodium pyrophosphate is used as a tartar control agent in toothpastes.
Disodium pyrophosphate can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.

In baking powder, Disodium pyrophosphate is often labeled as food additive E450.
In cured meats, Disodium pyrophosphate speeds the conversion of sodium nitrite to nitrite (NO2−) by forming the nitrous acid (HONO) intermediate, and can improve water-holding capacity.

Disodium pyrophosphate is also found in frozen hash browns and other potato products, where Disodium pyrophosphate is used to keep the color of the potatoes from darkening.

Disodium pyrophosphate can stabilize hydrogen peroxide solutions against reduction.
Disodium pyrophosphate can leave a slightly bitter aftertaste in some products, but "the Disodium pyrophosphate taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings."
In leather treatment, Disodium pyrophosphate can be used to remove iron stains on hides during processing.

When added to scalding water, Disodium pyrophosphate facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.
In petroleum production, Disodium pyrophosphate can be used as a dispersant in oil well drilling muds.
Disodium pyrophosphate is used in cat foods as a palatability additive.

Because Disodium pyrophosphate is slow acting and does not react quickly with baking soda, Disodium pyrophosphate is the most commonly used leavening acid for self rising flour for the home baker.
Per 21 C.F.R. § 137.180(a) 2018, self rising flour must contain enough leavening acid to neutralize the baking soda, but the combination of both can not exceed 4.5 parts per 100 parts flour.

The quantity of leavening acid needed hinges on Disodium pyrophosphate's neutralizing value (NV) which is defined as the quantity of baking soda needed to neutralize 100 parts of leavening acid.
For Disodium pyrophosphate, NV is 70.

Because Disodium pyrophosphate can have a slight bitter taste, Disodium pyrophosphate’s important to use sufficient baking soda in applications as well as use this leavening acid in combination with sugary goods such as doughnuts and cakes.

In canned tuna, Disodium pyrophosphate prevents harmless struvite crystals from forming.
Cake doughnuts are an important application for Disodium pyrophosphate, where initial gas production is necessary for buoyancy in a fryer system.
Also, Disodium pyrophosphate is useful for cakes, where initial gas production is necessary for consistency of pan fill.

Other non-bakery food applications of Disodium pyrophosphate include use as a chelating agent for processed potatoes, an emulsifying agent in cheeses and a curing accelerator in processed meats.
Disodium pyrophosphate can be used as a leavening chemical for bread to help Disodium pyrophosphate rise.

Disodium pyrophosphate's used in sausage to enhance flavor and color.
In french fries, the chemical reduces levels of a carcinogen called acrylamide.

Disodium pyrophosphate also prevents discoloration in potatoes and sugar syrups.
Disodium pyrophosphate is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.
Disodium pyrophosphate is widely used as thinner in oil well drilling muds and even as an industrial cleaner.

Disodium pyrophosphate's key advantages are:
Aids in the removal of calcium and reduces pH in cement contaminated fluids.
At low concentration levels, Disodium pyrophosphate is fast-acting and effective.

Aids break up clay particles and sediments, which enables them to be extracted during oil well development.
Disodium pyrophosphate is used in the chemical clean up of fluids which have been contaminated by cement.
Disodium pyrophosphate decreases the viscosity and gel strengths in freshwater drilling fluids.

Disodium pyrophosphate is used as a deflocculant (thinner) in freshwater mud systems.
Disodium pyrophosphate is often used to break up mud rings when water drilling and is also used to thin out cement before cementing casing.

In cementing applications, Disodium pyrophosphate is used for two primary purposes:
Contaminated drilling mud can result in fluid loss, thickening time, and viscosity.
Disodium pyrophosphate is used to disperse and displace drilling muds to avoid mud being affected by cement contamination.

Solids carrying fluid or drilling mud must be removed from the perforation channels and the rock face to allow a good cement bond and complete fill-up of the voids.
Incorporating Disodium pyrophosphate into the spacer will help remove residual muds and provide a cleaner surface to which the cement can bond.

Disodium pyrophosphate is used as an acidulant, buffering agent, coagulant, emulsifying agent, dispersing agent, protein modifier, and sequestrant.
Actively thins out reactive clays.
In non-dairy creamers, Disodium pyrophosphate is added to protect the proteins from heat dehydration, to stabilize the fat emulsion, and to buffer Disodium pyrophosphate.

Processed potatoes are protected from iron-induced darkening when treated with Disodium pyrophosphate.
Addition of Disodium pyrophosphate to albacore tuna during canning decreases or prevents formation of struvite crystals.

Disodium pyrophosphate is used in meat processing to accelerate development of red color in wieners, bologna, and other emulsion-type meat products.
Disodium pyrophosphate can be used as an emulsifying agent during cheese processing to produce a hard, non-melting cheese product.

Disodium pyrophosphate is Baking powder, used in baking and to control the fermenting speed, to increase the producing strength.
Disodium pyrophosphateis used in instant noodles to reduce time after subjecting to water.

Disodium pyrophosphate is also used in biscuits and cakes, to reduce fermenting time, to decrease the destroying, to maintain the clear gaps, finally to extend products storage.
Disodium pyrophosphate is used Vegetables (esp. potatoes) processing.

Disodium pyrophosphate is used Seafood, meat, cheese processing.
Disodium pyrophosphate is speedly fermentation, water retaining agent and quality improver, used in bread, biscuits, meat, aquatic products and so on.

As quality improver, Disodium pyrophosphate enhances complexation,PH value and Ionic strength.
According to rules, Disodium pyrophosphate's max adding quantity is 3.0g/KG in biscuits and 1.0-3.0g/KG in bread.

Disodium pyrophosphate is reactive not only with sodium bicarbonate, but also with calcium salts, proteins and heat.
Disodium pyrophosphate dispersant is used in much the same manner as polyphosphate dispersants and is subject to the same temperature limitations.
Due to its acidic nature, Disodium pyrophosphate is especially effective for treating cement contamination.

Disodium pyrophosphate dispersant is efficient for bentonite muds and is often used in conjunction with a tannin or quebracho compound.
Disodium pyrophosphate dispersant can also be used to treat calcium contamination, especially contamination resulting from cement.

Because of Disodium pyrophosphate's acidic nature, Disodium pyrophosphate dispersant is not normally used in muds where the pH exceeds 9.5.
Disodium pyrophosphate is one of the two acid components used in commercial baking powders.

Disodium pyrophosphate gives baking powder the time and temperature element contributing to the "Double Acting" power.
Regular Disodium pyrophosphate is used in cakes, sponges and refrigerated dough where a slower reactivity is desired.

Usage 1g of sodium bicarbonate to 1.38g Disodium pyrophosphate or as recipe indicates
Disodium pyrophosphate (SAPP), or disodium dihydrogen pyrophosphate, Disodium pyrophosphate's food grade is commonly used with sodium bicarbonate as a leavening agent in bakery products.

Also, Disodium pyrophosphate maintains the color in processed potatoes and also prevents struvite crystal in canned seafood.
The European food additive number for Disodium pyrophosphate is E450(i), Disodium pyrophosphate.
1. Bakery
2. Canned Sea Food
3. Potato Products

Disodium pyrophosphate is a white, crystalline powder or granular material with various applications in the food industry.

KEYWORDS:
7758-16-9, 231-835-0, Disodium dihydrogen diphosphate, Diphosphoric acid disodium salt, Pyrophosphoric Acid Disodium Salt, H5WVD9LZUD, Sodium pyrophosphate (Na2H2P2O7), DSSTox_RID_78658, CHEMBL3184949, LS-2432

Recommended use in following applications: as a constituent of baking powder, as a constituent of blanching solutions for preventing after-cooking darkening of potatoes, as a constituent of phosphate mized in meat processing, as a constituent of cheese emulsifying salts, as a general buffer and acidifying agent in foodstuffs, as a dispersant in oil well drilling muds, in leather treatment to remove iron stains, in the stabilization of hydrogen peroxide solutions, as a cleaning agent, in conjunction with sulphamic acidn in certain dairy applications, as seafood preservative.

To use: as leavening agent
Applications include food &|beverage (popular leavening agent found in baking powder, used in very sweet cakes which mask the off-tast, canned seafood, Disodium pyrophosphate is used to maintain color and reduce purge, frozen hash browns and other potato products, where Disodium pyrophosphate is used to keep the color of the potatoes from darkening)|agriculture (pet food used in cat foods as a palatability additive, removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter and |industrial (petroleum production, Disodium pyrophosphate can be used as a dispersant in oil well drilling muds, leather treatment to remove iron stains on hides, dairy applications for cleaning, remove soapstone).

Disodium pyrophosphate is used as a buffering and chelating agent, with many applications in the food industry.
Disodium pyrophosphate is one of the popular food additives and ingredients in most countries.

Disodium pyrophosphate used as buffering agent, leavening agent, sequestrant agent.
Disodium pyrophosphate can be used in canned food, ham, meat,baking powder and so on.

Disodium pyrophosphate is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.
Disodium pyrophosphate is used as a leavening agent, reducing zymosis time and can also be used as a water retention agent, and a quality improver for meat and sea food processing.
Disodium pyrophosphate is used strengthen the feed nutrition .

Disodium pyrophosphate, often abbreviated as SAPP is an edible phosphoric salt available as a white crystalline powder in the market.
In food and beverage industry, Disodium pyrophosphate is mostly used as a leavening agent in self-rising and baked goods and as a quality improver for meat and fish processing.

Besides food and beverage, Disodium pyrophosphate is also used in leather industry for leather processing and petroleum industry in the drilling of oil wells as dispersants.
Hence, the manufacturers are offering Disodium pyrophosphate in food grade or chemical so that their product can be utilized in all the above mentioned end-use industries and applications.

Consumers of Disodium pyrophosphate such as bakery producers are preferring the use of Disodium pyrophosphate as Disodium pyrophosphate can offer variable rates of reaction and leavening by gas production based on its granulation.
They are using Disodium pyrophosphate alone or in combination with other leavening agents depending on the requirement of product.

Disodium pyrophosphate, or SAPP, is used in the food industry.
More specially, Disodium pyrophosphate is used for certain types of baking powder and baking creams in addition to working as a leavening agent for prepared cake and doughnut mixes.
Disodium pyrophosphate maintains the natural white color of cooked potatoes.

Disodium pyrophosphate is used as chelating agent or buffering agent in many Food & Industrial applications.
Disodium pyrophosphate is used to remove Iron stains during processing of leather.
Disodium pyrophosphate is used as a dispersant in oil well drilling application.

Disodium pyrophosphate is a leavening agent, preservative, sequestrant, and buffer which is mildly acidic with a ph of 4.1.
Disodium pyrophosphate is moderately soluble in water, with a solubility of 15 g in 100 ml at 25°c.

Disodium pyrophosphate is used in doughnuts and biscuits for its variable gas release rate during the mixing, bench action, and baking process.
Disodium pyrophosphate is used in baking powder as a leavening agent.

Disodium pyrophosphate is used in canned fish products to reduce the level of undesired struvite crystals (magnesium ammonium phosphate hexahydrate) by complexing the magnesium.
Disodium pyrophosphate is used to sequester metals in processed potatoes.

Disodium pyrophosphate is currently used by the sausage industry to accelerate development of cured meat color.
The cured color accelerator was examined, through sensory evaluation and instrumental measurements, for its effects on the texture of frankfurters.

Disodium pyrophosphate is anhydrous form, pyrophosphate salt used in buffers.
Disodium pyrophosphate is used as a deflocculant (thinner) in freshwater mud systems.

Disodium pyrophosphate is often used to break up mud rings when water drilling and is also used to thin out cement before cementing casing.
Disodium pyrophosphate is used as leavening agent in baking powders, combining with sodium bicarbonate to release carbon dioxide.

Disodium pyrophosphate speeds the conversion of sodium nitrite to nitrite in cured meats and can improve water-holding capacity.
Disodium pyrophosphate is also found in potato products, where Disodium pyrophosphate prevents darkening.

Disodium pyrophosphate can be also be used in leather treatment; In some dairy applications for cleaning purposes and in petroleum production; etc.
Disodium pyrophosphate is used contaminated drilling mud can result in fluid loss, thickening time, and viscosity.

Disodium pyrophosphate is used to disperse and displace drilling muds to avoid mud being affected by cement contamination.
Disodium pyrophosphate is used solids carrying fluid or drilling mud must be removed from the perforation channels and the rock face to allow a good cement bond and complete fill-up of the voids.

Incorporating Disodium pyrophosphate into the spacer will help remove residual muds and provide a cleaner surface to which the cement can bond.
Disodium pyrophosphate can be used to remove iron stains on hides during processing.

Disodium pyrophosphate can stabilize hydrogen peroxide solutions against reduction.
Disodium pyrophosphate can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.

When added to scalding water, Disodium pyrophosphate facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.
In petroleum production, Disodium pyrophosphate can be used as a dispersant in oil well drilling muds.

Disodium pyrophosphate is used in cat foods as a palatability additive.
Disodium pyrophosphate is used as a tartar control agent in toothpastes.

Disodium pyrophosphate can be used to remove iron stains on hides during processing.
Disodium pyrophosphate can stabilize hydrogen peroxide solutions against reduction.

Disodium pyrophosphate can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.
when added to scalding water, Disodium pyrophosphate facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.

In petroleum production, Disodium pyrophosphate can be used as a dispersant in oil well drilling muds.
Disodium pyrophosphate is used in cat foods as a palatability additive.

Disodium pyrophosphate is used as a tartar control agent in toothpastes
Disodium pyrophosphate dispersant is used in much the same manner as polyphosphate dispersants and is subject to the same temperature limitations.

Due to its acidic nature, Disodium pyrophosphate is especially effective for treating cement contamination.
Disodium pyrophosphate dispersant is efficient for bentonite muds and is often used in conjunction with a tannin or quebracho compound.

Disodium pyrophosphate dispersant can also be used to treat calcium contamination, especially contamination resulting from cement.
Because of its acidic nature, SAPP dispersant is not normally used in muds where the pH exceeds 9.5.

Disodium pyrophosphate food grade is used as an acid component in baking powder; as a chelating agent or combines with other polyphosphates to sequester magnesium and iron ions, e.g. chelate iron during the processing of potatoes to prevent a dark discoloration.
Disodium pyrophosphate can be used as a leavening chemical for bread to help Disodium pyrophosphate rise.

Disodium pyrophosphate's used in sausage to enhance flavor and color.
In french fries, the chemical reduces levels of a carcinogen called acrylamide, according to an article from the Center for Science in the Public Interest.

Disodium pyrophosphate also prevents discoloration in potatoes and sugar syrups.
In canned tuna, Disodium pyrophosphate prevents harmless struvite crystals from forming.

Disodium pyrophosphate is used together with baking powder as a leavening agent to release carbon dioxide.
Disodium pyrophosphate is ideal for refrigerated doughs, cakes, muffins and pancake mixes where a slow reaction rate is desired.

Disodium pyrophosphate is often used with fast-acting leavenings such as monocalcium phosphate in double-acting baking powder or sometimes added with another slow action leavening acid, GDL.
Disodium pyrophosphate can be used to replace sulfur dioxide, sulfites and bisulfites to maintain the appearance and texture of cooked potato products.

The application of Disodium pyrophosphate reduces the dark color from after-cooking darkening in cooked and processed potato products, such as in oil-blanched french fries and potato salad.
Disodium pyrophosphate is Baking powder, used in baking and to control the fermenting speed, to increase the producing strength.

Disodium pyrophosphate is used in instant noodles to reduce time after subjecting to water.
Disodium pyrophosphate is also used in biscuits and cakes, to reduce fermenting time, to decrease the destroying, to maintain the clear gaps, finally to extend products storage.

Disodium pyrophosphate is speedly fermentation, water retaining agent and quality improver, used in bread, biscuits, meat, aquatic products and so on.
As quality improver, Disodium pyrophosphate enhances complexation,PH value and Ionic strength.

According to rules, Disodium pyrophosphates max adding quantity is 3.0g/KG in biscuits and 1.0-3.0g/KG in bread.
Disodium pyrophosphate is used in sausages to enhance flavor and color.
Disodium pyrophosphate is used in biscuits and cakes, Disodium pyrophosphate can shorten the fermentation time, reduce Disodium pyrophosphate breakage rate, loosen the gaps neatly, and prolong the storage period.

Disodium pyrophosphate is used as a quality improver for bakery foods such as bread, biscuits, meat and aquatic products, etc.
Disodium pyrophosphate can improve the complex metal ions, PH value and ionic strength of foods, thereby improving the adhesion and water holding capacity of foods. In French Fries, Disodium pyrophosphate SAPP can reduce levels of a carcinogen called acrylamide.

Disodium pyrophosphate can also prevent discoloration of potatoes and syrup.
In canned tuna, Disodium pyrophosphate can prevent the formation of harmless struvite crystals.
In canned seafood, Disodium pyrophosphate can retain color during cooking and reduce cleaning.

In cured meats, Disodium pyrophosphate accelerates the conversion of sodium nitrite to nitrite by forming a nitrous acid intermediate and can improve water retention.
Disodium pyrophosphate is used in frozen hash browns and other potato products to prevent potatoes from darkening.
Disodium pyrophosphate may leave a slightly bitter aftertaste in some products, but adding calcium ions, sugar, or flavoring can mask the taste.

In leather processing, Disodium pyrophosphate can be used to remove iron stains from raw hides during processing.
Disodium pyrophosphate can stabilize the hydrogen peroxide solution against reduction.
In certain dairy applications, Disodium pyrophosphate can be used with sulfamic acid for cleaning, especially soapstone removal.

In oil production, Disodium pyrophosphate can be used as a dispersant for oil well drilling mud.
Disodium pyrophosphate is used as a tartar control agent in toothpaste.
Disodium pyrophosphate is commonly used as a leavening agent in baked goods, such as cakes, muffins, pancakes, waffles, and biscuits.

Disodium pyrophosphate works by releasing carbon dioxide gas when Disodium pyrophosphate reacts with alkalis like baking soda (sodium bicarbonate) in the presence of moisture and heat.
This gas production causes the dough or batter to rise, resulting in the characteristic light and airy texture of these products.
Disodium pyrophosphate is an essential component of double-acting baking powder, a leavening agent used in a wide range of baked goods.

Double-acting baking powder releases gas in two stages: once when mixed with wet ingredients and again when exposed to the heat of the oven.
This two-stage action provides better control over the leavening process and helps achieve consistent results in baking.
Disodium pyrophosphate acts as a pH buffer in various food products.

Disodium pyrophosphate helps control and stabilize the pH (acidity or alkalinity) of food items, preventing undesirable changes in flavor, color, and texture.
Disodium pyrophosphate is particularly useful in processed foods to maintain the desired pH level.

Disodium pyrophosphate serves as an emulsifying agent.
Disodium pyrophosphate helps blend ingredients that would not naturally mix, such as oil and water.

This property is valuable in the production of salad dressings, sauces, and some dairy products to create stable and uniform mixtures.
Disodium pyrophosphate is used in the meat industry as a pH regulator and moisture retention agent in various processed meat products.

Disodium pyrophosphate helps improve the texture and quality of these products.
Disodium pyrophosphate can be found in certain dairy products, especially processed cheeses, to enhance their melting and textural characteristics.
Disodium pyrophosphate assists in achieving a smooth and creamy texture in cheese-based products.

In potato-based products like French fries and hash browns, Disodium pyrophosphate is employed to prevent discoloration and maintain the appealing color of the potatoes during processing and frying.
Disodium pyrophosphate is used in canned seafood products to help maintain product quality and texture, particularly in products like canned tuna.
Disodium pyrophosphate may be used in various other food items, such as canned soups, gravies, and sauces, where Disodium pyrophosphate contributes to texture and stability.

Benefits of Disodium pyrophosphate:
Controlled leavening acid
Prevents oxidation/colour change
Humectant
Buffering agent
Stabiliser
Acidulant

Functions of Disodium pyrophosphate:
Leavening acids provide air and volume to the baked good structure, but also affect the characteristics of the dough.
Besides reacting with baking soda to produce the gas carbon dioxide, these acids form ionic bonds with the starches and proteins in the dough.

Disodium pyrophosphate dissolves readily to form the anion pyrophosphate which interacts with the proteins in a baked good system to provide a moist texture.
Also, Disodium pyrophosphate provides a buffer system for the dough in the pH range 7.3-7.5, which influences the color of the baked product.

Advantages of Disodium pyrophosphate:
Widely available and economical thinner effective for treatment of cement contamination
Concentrated chemical that is effective at low treatment levels
Can be used with most water-base mud types

Preparation of Disodium pyrophosphate:
Disodium pyrophosphate is produced from sodium dihydrogenmonophosphate by heating at 200-250℃:
Na2CO3+2H3PO4→2NaH2PO4+H2O+CO2↑
2NaH2PO4→Na2H2P2O7+H2O

Disodium pyrophosphate is a condensed phosphate, commonly synthesized by the neutralization of phosphoric acid with sodium hydroxide or sodium carbonate at the ratio of 1:1 to produce monosodium phosphate (NaH2PO4), and then heated approximately 250°C to remove the water.
2 NaH2PO4 → Na2H2P2O7 + H2O

Production of Disodium pyrophosphate:

Commercial Production:
Disodium pyrophosphate is manufactured by partially neutralizing food grade phosphoric acid with sodium hydroxide or sodium carbonate to form monosodium phosphate.
Dehydration of monosodium phosphate at 250°C will form SAPP.
Currently, there is no known natural method for the production of Disodium pyrophosphate.

Origin of Disodium pyrophosphate:
In the eighteenth century and earlier, bakers relied upon yeast to leaven all baked goods.
However, using yeast for leavening baked goods was tedious and bakers began to explore the use of chemical leavening systems.
In 1846, baking soda was discovered as a leavening agent and that led to further discoveries of acids to react with baking soda, such as SAPP.

Commercially, Disodium pyrophosphate was introduced into baking powder blends towards the end of the nineteenth century.
Disodium pyrophosphate is a preferred leavening acid because Disodium pyrophosphate is less expensive and stronger than other leavening acids introduced previously.

Safety of Disodium pyrophosphate:
As with many powdered food ingredients, inhaling fine Disodium pyrophosphate powder can lead to respiratory irritation.
Inhaling the dust should be avoided.
Similarly, direct eye contact with the powder may cause irritation, and Disodium pyrophosphate is advisable to take precautions when handling the dry powder.

Disodium pyrophosphate itself is not typically considered a skin irritant, prolonged or repeated skin contact with the powder may lead to dryness or minor irritation for some individuals.
Disodium pyrophosphate is recommended to minimize skin contact and use protective gloves when handling SAPP in its dry form.

Disodium pyrophosphate is intended for use in food and is considered safe for consumption when used within established limits.
However, ingestion of the undiluted dry powder is not recommended, as Disodium pyrophosphate may cause discomfort and digestive upset.

As with any food additive, Disodium pyrophosphate should be used in accordance with recommended concentrations.
To ensure the safe use of Disodium pyrophosphate, Disodium pyrophosphate is crucial to adhere to food safety regulations and guidelines established by local and international authorities, such as the U.S. Food and Drug Administration (FDA) in the United States and similar agencies in other regions.

Disodium pyrophosphate is considered safe for consumption when used in accordance with established regulations and guidelines.
Disodium pyrophosphate is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA).

Handling and Storage of Disodium pyrophosphate:

Precautions for safe handling:

Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.

Stability and Reactivity of Disodium pyrophosphate:

Reactivity:
No data available

Chemical stability:
Stable under recommended storage conditions.

Possibility of hazardous reactions:
No data available

Conditions to avoid:
No data available

First Aid Measures of Disodium pyrophosphate:

General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.

If inhaled:
If breathed in, move person into fresh air.
Consult a physician.

In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed:
Rinse mouth with water.
Consult a physician.

Indication of any immediate medical attention and special treatment needed:
No data available

Accidental Release Measures of Disodium pyrophosphate:

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.

Fire Fighting Measures of Disodium pyrophosphate:

Extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Further information:
No data available

Exposure Controls/personal Protection of Disodium pyrophosphate:

Personal protective equipment:

Eye/face protection:
Use safety glasses with side-shields.

Skin protection:
Handle with gloves.
Wash and dry hands.

Body Protection:
Use Impervious clothing.

Control of environmental exposure:
Do not let product enter drains.

Identifiers of Disodium pyrophosphate:
CAS Registry Number: 7758-16-9
Additional Names: Disodium dihydrogen pyrophosphate
Molecular Formula: H2Na2O7P2
Molecular Weight: 221.94
Percent Composition: H 0.91%, Na 20.72%, O 50.46%, P 27.91%
Line Formula: Na2H2P2O7
Literature References: Prepn: Bell, Inorg. Synth. 3, 98 (1950).
Properties: White, fused masses or powder. Dec at 220°. d (hexahydrate) 1.86. Sol in water, the soln having an acid reaction.
Density: d (hexahydrate) 1.86
Use: Chiefly in baking powders.

Properties of Disodium pyrophosphate:
Melting point: decomposes 220℃ [MER06]
Density (hexahydrate): 1.86
vapor pressure: 0Pa at 20℃
storage temp.: -70°C
solubility: H2O: 0.1 M at 20 °C, clear, colorless
form: white powder
color: White to Off-White
PH: 3.5-4.5 (20℃, 0.1M in H2O, freshly prepared)
Water Solubility: Fully miscible in water. Insoluble in alcohol and ammonia.
λmax: λ: 260 nm Amax: 0.11
λ: 280 nm Amax: 0.09
Merck: 13,8643
Stability: Stable.
InChI: InChI=1S/Na.H4O7P2.H/c;1-8(2,3)7-9(4,5)6;/h;(H2,1,2,3)(H2,4,5,6);
InChIKey: IQTFITJCETVNCI-UHFFFAOYSA-N
SMILES: O(P(O)(O)=O)P(O)(O)=O.[NaH]
LogP: -3.420 (est)

Appearance Form: powder
Color: white
pH: No data available
Melting point/freezing point: > 450 °C

Relative density: 2,63 at 22,5 °C
Water solubility: 170 g/l at 20 °C

Chemical formula: Na2H2P2O7
Molar mass: 221.94 g/mol
Appearance: White odorless powder

Density: 2.31 g/cm3
Melting point: >600 °C
Solubility in water: 11.9 g/100 mL (20 °C)
Refractive index (nD): 1.4645 (hexahydrate)
Assay: ≥ 95.0 %
Moisture (at 110oC): ≤ 0.50 %
pH (1 % Solution): 4.0 – 4.6
Water Insoluble Matter: ≤ 0.1 %
Phosphate (P2O5): 63.0 – 64.5 %

Rate of CO2 Release (at 2 mins): 13.0 – 17.0 %
Neutralising Value: ≥ 72.0 %
Fluoride (As F): ≤ 10.0 ppm
Arsenic (As As): ≤ 3.0 ppm
Lead (As Pb): ≤ 2.0 ppm
Cadmium (As Cd): ≤ 1.0 ppm
Heavy Metals (As Pb): ≤ 10.0 ppm
Mercury (As Hg): ≤ 1.0 ppm

IUPAC Name: Di-sodium di-hydrogen di-phosphate
Molecular Formula: Na2H2P2O7
Molecular Weight: 222.00
Appearance: White fine Powder
PH Range (1% w/v): 3.5 – 4.5
Pyro % (minimum): 98.00
P2O5 content % (minimum): 62.00
‘Na’ Content % (minimum): 20.00
Iron as ‘Fe’ content %: 0.02
Chloride as ‘Cl’ content %: 0.2
Sulfate as ‘SO4’ content %: 0.03

Specification of Disodium pyrophosphate:
Cyclic Phosphates: ≤ 2%
Arsenic: ≤ 3 ppm
Lead: ≤ 2 ppm
Fluoride: ≤ 10 ppm
Loss on drying: ≤ 0.5%
Assay: ≥ 95%
pH value: 3.8 - 4.2

Releated Compounds of Disodium pyrophosphate:
Tetrasodium pyrophosphate

Other anions:
Disodium phosphate
Pentasodium triphosphate
Sodium hexametaphosphate

Other cations:
Calcium pyrophosphate
Dipotassium pyrophosphate
DISODIUM SALT
Disodium salt, with the chemical formula Na2S2O3·5H2O, is an efflorescent crystalline substance that dissolves well in water and is used in various applications such as gold mining, water treatment, analytical chemistry, photographic film development, and medicine.
Medically, Disodium salt is employed as an antidote for cyanide poisoning, a treatment for calciphylaxis, and to reduce side effects of cisplatin, a cancer medication, highlighting its inclusion in the World Health Organization's List of Essential Medicines.
In photography, Disodium salt acts as a fixer to dissolve silver salts from negatives, while in water treatment, it neutralizes chlorine in tap water and swimming pools, showcasing its versatility in industrial and medical applications.

CAS Number: 7772-98-7
EC Number: 231-867-5
Chemical Formula: Na2S2O3
Molar Mass: 158.11 g/mol

Synonyms: SODIUM THIOSULFATE, 7772-98-7, sodiumthiosulfate, Disodium thiosulfate, Hypo, Chlorine Control, Thiosulfuric acid, disodium salt, Sodium thiosulfate, anhydrous, disodium sulfurothioate, MFCD00003499, Na2S2O3, L0IYT1O31N, Thiosulfuric acid (H2S2O3), disodium salt, Sodothiol, sodium sulfothioate, Sodothiol; Sulfactol; Sulfothiorine, Chlorine Cure, Declor-It, Hypo (VAN), HSDB 592, EINECS 231-867-5, Na2O3S2, UNII-L0IYT1O31N, AI3-01237, sodium thiosulfat, sodium thio-sulfate, Sodium oxide sulfide, Hypo alcohol, in ethanol, anhydrous sodium thiosulfate, EC 231-867-5, DISODIUM THIOSULPHATE, sodium thiosulfate (anhydrous), SODIUM THIOSULFATE [MI], CHEMBL3753202, DTXSID9042417, SODIUM THIOSULFATE [HSDB], CHEBI:132112, Sodium thiosulfate, AR, >=98%, Sodium thiosulfate, LR, >=97%, SODIUM THIOSULFATE [WHO-DD], Sodium thiosulfate, p.a., 98.0%, AKOS015856704, AKOS016372312, SODIUM THIOSULFATE ANHYDROUS [II], BP-21059, Sodium thiosulfate, ReagentPlus(R), 99%, FT-0696570, O0522, D78333, Sodium thiosulfate, SAJ first grade, >=90.0%, disodium;dioxido-oxo-sulfanylidene-lambda6-sulfane, Q339866, Sodium thiosulfate, >=99.99% trace metals basis, Sodium thiosulfate, Vetec(TM) reagent grade, 99%, Thiosulfuric acid (H2S2O3), sodium salt (1:2), Sodium thiosulfate, anhydrous, Trace metals grade 99.99%, Sodium thiosulfate, purum p.a., anhydrous, >=98.0% (RT), Sodium thiosulfate [JAN] [USAN] [Wiki], Sodium hyposulfite, 231-791-2 [EINECS], 231-867-5 [EINECS], 7772-98-7 [RN], Dinatriumsulfurothioat [German] [ACD/IUPAC Name], Disodium sulfurothioate [ACD/IUPAC Name], Disodium thiosulfate, Hypo alcohol, MFCD00003499 [MDL number], sodium thiosulphate, Sulfurothioate de disodium [French] [ACD/IUPAC Name], Thiosulfuric acid disodium salt, Thiosulfuric acid, disodium salt, anhydrous sodium thiosulfate, antichlor, Declor-It, disodium sulfanesulfite, DISODIUM SULFANIDESULFONATE, DISODIUM THIOSULPHATE, disodium;dioxido-oxo-sulfanylidene-λ6-sulfane, Hypo, S-Hydril, sodium oxide sulfide, Sodium oxide sulfide (Na2S2O3 ), Sodium thiosulfate (Na2 S2 O3 ), Sodium thiosulfatemissing, Sodothiol, Sulfothiorine

Disodium salt is an inorganic compound with the formula Na2S2O3·xH2O, where x indicates the number of water molecules in Disodium salt.
Typically Disodium salt is available as the white or colorless pentahydrate, Na2S2O3·5H2O.
The solid is an efflorescent (loses water readily) crystalline substance that dissolves well in water.

Disodium salt is used in gold mining, water treatment, analytical chemistry, the development of silver-based photographic film and prints, and medicine.
The medical uses of Disodium salt include treatment of cyanide poisoning and pityriasis.
Disodium salt is on the World Health Organization's List of Essential Medicines.

Disodium salt also called as thiosulfuric acid or Sodium thiosulfate is an inorganic salt that is also available in the pentahydrates.
Disodium salt has a chemical formula of Na2S2O3.

Disodium salt appears as a bright white colourless crystal or even in powder form.
Disodium salt is known to possess Alkaline nature when decomposed to sulphide and sulfate in the air.

Disodium salt readily dissolves in water giving thiosulfate ions, one of the useful reducing agents.
The Copper (II) sulfate dissolves to give the cupric ion; in regard to a redox reaction with the thiosulfate, the cupric particles act like oxidizing agents.

Disodium salt is an inorganic sodium salt composed of sodium and thiosulfate ions in a 2:1 ratio.
Disodium salt has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug.
Disodium salt contains a thiosulfate(2-).

Disodium salt is an industrial chemical which also has a long medical history.
Disodium salt was originally used as an intravenous medication for metal poisoning.

Disodium salt has since been approved for the treatment of certain rare medical conditions.
These include cyanide poisoning, calciphylaxis, and cisplatin toxicity.

In vitro assays have demonstrated that Disodium salt is an anti-inflammatory and neuroprotective agent.
Disodium salt therefore has potential for treating neurodegenerative diseases such as Alzheimer disease and Parkinson disease.

NaSH has similar properties and is somewhat more powerful than Disodium salt in these in vitro assays.
However Disodium salt has already been approved as an orally available treatment.
Disodium salt may therefore be a readily available candidate for treating neurodegenerative disorders such as Alzheimer disease and Parkinson disease.

Disodium salt is an industrial compound which has a long history of medical use.

Since Disodium salt is employed as a food preservative, the general population is widely exposed to this non-toxic compound.
For example, Disodium salt is typically added to table salt at less than 0.1% and to alcoholic beverages at less than 0.0005%.
Disodium salt is generally available as a non-prescription oral product.

Disodium salt is an inorganic sodium salt with the formula Na2S2O3 composed of a 2:1 mixture of sodium and thiosulfate ions.
The uses of Disodium salt are numerous, in particular as a fixing agent or to neutralize the effect of biocides such as dichlor, iodine and other oxidants, also, Disodium salt has a role as an antidote to cyanide poisoning, nephroprotective agent and antifungal.

Disodium salt is usually added to table salt at less than 0.1% and to alcoholic beverages at less than 0.0005%.
Disodium salt is usually available as an oral product without a prescription.

Disodium salt solutions are almost exclusively used to standardize Iodine solutions or as back-titrants in titrations using Iodine.
Solutions of Disodium salt are most commonly standardized with Potassium Dichromate or Potassium Iodate solutions, which generate Iodine from Iodide.
Starch indicator is typically used.

The reaction with Iodine is:
I3- + 2 S2O32- → 3 I- + S4O62- (Dithionite ion)

Titrations with standard Disodium salt solution are best conducted in the pH 5 - 9 range.
Since this is not always possible, the titrations should be conducted rapidly and with adequate stirring to insure rapid reaction of the Thiosulfate, thus minimizing any acid-accelerated decomposition.
This will also minimize the acid-catalyzed oxidation of Iodide (usually present in a titration involving Thiosulfate) to Iodate, which could lead to decreased accuracy.

Disodium salt solutions are subject to bacterial decomposition and chemical deterioration.
Disodium salt solutions decompose in acid solution resulting in the evolution of Sulfur Dioxide gas and precipitation of elemental Sulfur.
Contact with Carbon Dioxide in the air can produce the acidity leading to this decomposition, which is faster in more dilute Thiosulfate solutions.

Disodium salt, also known as sodium hydrosulfite, is used as an antidote to cyanide poisoning, but several studies have demonstrated that Disodium salt efficacy in some pathological conditions is related to ectopic calcification.
The mechanisms of action, by which Disodium salt exerts Disodium salt inhibitory effect on vascular mineralization, are not yet clear.

Disodium salt has been postulated that Disodium salt: (i) forms with calcium a more soluble complex than calcium phosphate and calcium oxalate, (ii) has antioxidant activity improving endothelial function, (iii) has acidosis properties.
However, O'Neil and Hardcastle demonstrated that the inhibitor effect of Disodium salt seems to be independent on calcium interactions or on pH, but could be due to a direct extracellular effect on calcification induced by cellular injury releasing cell debris and matrix vesicles.

Nevertheless, Disodium salt is used to treat calciphylaxis, kidney stones, uremic vascular calcification and coronary artery calcification.
Recently, intravenous Disodium salt has been used in a young boy with several deleterious mutations in ABCC6, ENPP1 and HBB genes and, over a period of 6 months, calcific stenosis of celiac and mesenteric arteries was not anymore detectable on arterial ultrasonography.
Follow-up evidenced a temporary efficacy of Disodium salt.

Two clinical trials highlight that Disodium salt treatment can be safe and can reduce the rate of coronary artery calcification progression in hemodialysis patients.

Disodium salt may be used to lessen some of the side effects of cisplatin (a cancer medicine).
Disodium salt is also used with another medicine in the emergency treatment of cyanide poisoning.

Disodium salt is also used to reduce the risk of hearing loss in children 1 month of age and older who are receiving medicines (eg, cisplatin) for cancer that have not spread throughout the body.
This medicine is to be given only by or under the immediate supervision of your doctor.

Disodium salt is available in the following dosage forms:
Solution

Applications of Disodium salt:
We find various applications of Disodium salt in different fields such as medicine, photography, gold extraction and many other areas.

The other uses of Disodium salt are below;
Disodium salt is used in the manufacture of patinas
In industries, the chemical is used for the dechlorination of small water bodies like ponds, aquariums, etc

In photography, the chemical is used as a fixing agent to dissolve the silver salts from the negatives
The chemical can be utilized as a cleansing agent when dissolved in a vast quantity of warm water

Disodium salt is well-used as an antidote agent concerning the cyanide poisoning
In the medical field, Disodium salt is employed in the pharmaceutical preparations such as anionic surfactant aiding in dispersion
Apart from the above uses, the chemical substance also finds Disodium salt applications in the water treatment, leather tanning, neutralizing bleach, gold extraction, photographic film processing, and also in chemical heating pads.

Uses of Disodium salt:
Disodium salt is used predominantly in industry. For example, Disodium salt is used to convert dyes to their soluble colorless forms, which are called leuco.
Disodium salt is also used to bleach "wool, cotton, silk, ...soaps, glues, clay, sand, bauxite, and... edible oils, edible fats, and gelatin."

Disodium salt is added in small quantities to ammonium thiosulfate, which is used as a photographic fixing salt.
The hydrated salt is used as an anti-chlorine in bleaching, in wastewater purification, for reduction of dichromate in chromed leather production, and as a solvent for silver chloride in the chloride roasting of silver-containing minerals.

Disodium salt is used in paper bleaching, photography (fixer), silver extraction, dyeing textiles (mordant), and leather manufacturing.
Disodium salt is also used as an antidote for cyanide poisoning and in vet medicine for bloat and ringworm.

The action of Disodium salt is multifactorial since Disodium salt is a chelating agent of divalent cations, which also has antioxidant and vasodilator properties.

Disodium salt is used to treat cyanide poisoning.
Disodium salt is also used to reduce the side effects of the cancer drug cisplatin.

Disodium salt is used to treat, under certain conditions, calciphylaxis, kidney stones, uremic vascular calcification and coronary artery calcification.
Disodium salt would promote the healing of skin ulcerations, especially when treatment with hyperbaric oxygen therapy is applied concurrently.

Disodium salt is added in small amounts to ammonium thiosulfate, which is used as a photographic fixing salt.
Hydrated salt is used as an anti-chlorine in bleaching, Disodium salt simply reacts and forms sodium hydrogen sulfate or sodium bisulfate which is an inactive salt.

Medical uses:
Disodium salt is used in the treatment of cyanide poisoning.
Other uses include topical treatment of ringworm and tinea versicolor and treating some side effects of hemodialysis and chemotherapy.
In September 2022, the U.S. Food and Drug Administration (FDA) approved Disodium salt under the trade name Pedmark to lessen the risk of ototoxicity and hearing loss in infant, child, and adolescent cancer patients receiving the chemotherapy medication cisplatin.

Photographic processing:
Silver halides, e.g., AgBr, typical components of photographic emulsions, dissolve upon treatment with aqueous thiosulfate.
This application as a photographic fixer was discovered by John Herschel.

Disodium salt is used for both film and photographic paper processing; the Disodium salt is known as a photographic fixer, and is often referred to as 'hypo', from the original chemical name, hyposulphite of soda.
Ammonium thiosulfate is typically preferred to Disodium salt for this application.

Neutralizing chlorinated water:
Disodium salt is used to dechlorinate tap water including lowering chlorine levels for use in aquariums, swimming pools, and spas (e.g., following superchlorination) and within water treatment plants to treat settled backwash water prior to release into rivers.
The reduction reaction is analogous to the iodine reduction reaction.

In pH testing of bleach substances, Disodium salt neutralizes the color-removing effects of bleach and allows one to test the pH of bleach solutions with liquid indicators.
The relevant reaction is akin to the iodine reaction: thiosulfate reduces the hypochlorite (the active ingredient in bleach) and in so doing becomes oxidized to sulfate.

The complete reaction is:
4 NaClO + Na2S2O3 + 2 NaOH → 4 NaCl + 2 Na2SO4 + H2O

Similarly, Disodium salt reacts with bromine, removing the free bromine from the solution.
Solutions of Disodium salt are commonly used as a precaution in chemistry laboratories when working with bromine and for the safe disposal of bromine, iodine, or other strong oxidizers.

Industry Uses:
Agricultural chemicals (non-pesticidal)
Chain transfer agent
Cleaning agent
Corrosion inhibitor
Intermediate
Intermediates
Laboratory chemicals
Not Known or Reasonably Ascertainable
Other (specify)
Oxidizing/reducing agents
Processing aids not otherwise specified
Processing aids, not otherwise listed
Processing aids, specific to petroleum production
Reducing agent
Solids separation agents
Solvents (for cleaning or degreasing)
Surface modifier
Tanning agents not otherwise specified

Consumer Uses:
Cleaning agent
Not Known or Reasonably Ascertainable
Processing aids, not otherwise listed
Solvents (for cleaning or degreasing)

Industrial Processes with risk of exposure:
Pulp and Paper Processing
Sewer and Wastewater Treatment
Leather Tanning and Processing
Photographic Processing
Textiles (Printing, Dyeing, or Finishing)
Metal Extraction and Refining

Activities with risk of exposure:
Applying metallic patinas

Properties of Disodium salt:
Disodium salt is a colorless monoclinic crystal or white crystalline powder, odorless and salty.
The relative density for this is 1.667.

Water-soluble, Disodium salt solubility at 100°C is 231 g/100 ml of vapour.
Disodium salt salt decomposes at high temperatures to give sodium sulfate with sodium polysulfide.
Disodium salt dissociates in water and some other polar solvents.

When exposed to dilute acids such as dilute hydrochloric acid, Disodium salt salt undergoes a decomposition reaction to yield sulfur with sulfur dioxide.

Disodium salt possesses various chemical and physical properties as given below;
Disodium salt appears as a white translucent colourless crystal and is an inorganic compound.
Disodium salt is water-soluble substance and is also soluble in oil of turpentine but not in the alcohol.

Disodium salt has a melting point of about 48 to 52 C.
Disodium salt is highly stable in nature and is said to be incompatible with some strong oxidizing agents and strong acids.

Thiosulfate anion readily reacts with the dilute acids producing sulphur, sulphur dioxide and also water.
The chemical has a density measuring about 1.667 g/mL.

Structure of Disodium salt:
Two polymorphs are known as pentahydrate.
The anhydrous salt exists in several polymorphs.

In the solid state, the thiosulfate anion is tetrahedral in shape and is notionally derived by replacing one of the oxygen atoms by a sulfur atom in a sulfate anion.
The S-S distance indicates a single bond, implying that the terminal sulfur holds a significant negative charge and the S-O interactions have more double-bond character.

Disodium salt has a chemical formula of Na2S2O3 and the molar mass of about 158.11 g/mol.
Disodium salt well exists in the form of pentahydrate salts (Na2S2O3.5H2O), having a molar mass measuring about 248.18 g/mol.

The Disodium salt is an ionic compound which consists of two cations of sodium atom (Na+) and a negatively charged anion of thiosulfate (S2O3-).
Here the central atom consisting of sulphur bonds to the three oxygen atoms and also another atom of sulphur, all these through a single and also double bonds possessing resonance character.
The solid also exists in a monoclinic crystalline structure.

The thiosulfate anion is usually a tetrahedral structure and, is obtained by the replacement of one of the atoms of oxygen by the use of sulfur atom in the sulfate anion.

Manufacturing Methods of Disodium salt:
By-product liquor from sodium sulfide production is reacted with sulfur dioxide to yield Disodium salt; or organic nitro compounds are boiled with sodium polysulfide solution to yield a leach liquor of Disodium salt, which is then purified, concentrated and crystallized

By dissolving sulfur in sodium sulfite soln & then crystallizing.
Disodium salt is also prepared from waste liquors obtained in prodn of sodium sulfide, liquors containing sodium carbonate & small amt of sodium sulfite & sodium sulfate in addn to sulfide.

General Manufacturing Information of Disodium salt:

Industry Processing Sectors:
All Other Basic Inorganic Chemical Manufacturing
All Other Basic Organic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing
Computer and Electronic Product Manufacturing
Electrical Equipment, Appliance, and Component Manufacturing
Fabricated Metal Product Manufacturing
Machinery Manufacturing
Mining (except Oil and Gas) and support activities
Miscellaneous Manufacturing
Not Known or Reasonably Ascertainable
Oil and Gas Drilling, Extraction, and Support activities
Paint and Coating Manufacturing
Paper Manufacturing
Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing
Petrochemical Manufacturing
Petroleum Refineries
Photographic Film, Paper, Plate, and Chemical Manufacturing
Services
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
Synthetic Dye and Pigment Manufacturing
Textiles, apparel, and leather manufacturing
Transportation Equipment Manufacturing
Utilities
Wholesale and Retail Trade

Production of Disodium salt:
On an industrial scale, Disodium salt is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture.

In the laboratory, this salt can be prepared by heating an aqueous solution of sodium sulfite with sulfur or by boiling aqueous sodium hydroxide and sulfur according to this equation:
6 NaOH + 4 S → 2 Na2S + Na2S2O3 + 3 H2O

Principal reactions of Disodium salt:

Upon heating to 300 °C, Disodium salt decomposes to sodium sulfate and sodium polysulfide:
4 Na2S2O3 → 3 Na2SO4 + Na2S5

Thiosulfate salts characteristically decompose upon treatment with acids.
Initial protonation occurs at sulfur.

When the protonation is conducted in diethyl ether at −78 °C, H2S2O3 (thiosulfuric acid) can be obtained.
Disodium salt is a somewhat strong acid with pKas of 0.6 and 1.7 for the first and second dissociations, respectively.

Under normal conditions, acidification of solutions of this salt excess with even dilute acids results in complete decomposition to sulfur, sulfur dioxide, and water:
8 Na2S2O3 + 16 HCl → 16 NaCl + S8 + 8 SO2 + 8 H2O

Coordination chemistry:
Thiosulfate is a potent ligand for soft metal ions.
A typical complex is [Pd(S2O3)2(ethylenediamine)]2−, which features a pair of S-bonded thiosulfate ligands.

Disodium salt and ammonium thiosulfate have been proposed as alternative lixiviants to cyanide for extraction of gold.
The advantages of this approach are that (i) thiosulfate is far less toxic than cyanide and (ii) that ore types that are refractory to gold cyanidation (e.g. carbonaceous or Carlin-type ores) can be leached by thiosulfate.
Some problems with this alternative process include the high consumption of thiosulfate, and the lack of a suitable recovery technique, since [Au(S2O3)2]3− does not adsorb to activated carbon, which is the standard technique used in gold cyanidation to separate the gold complex from the ore slurry.

Iodometry:

In analytical chemistry, the most important use comes because the thiosulfate anion reacts stoichiometrically with iodine in aqueous solution, reducing Disodium salt to iodide as the thiosulfate is oxidized to tetrathionate:

2 S2O2−3 + I2 → S4O2−6 + 2 I−

Due to the quantitative nature of this reaction, as well as because Na2S2O3·5H2O has an excellent shelf-life, Disodium salt is used as a titrant in iodometry.
Na2S2O3·5H2O is also a component of iodine clock experiments.

This particular use can be set up to measure the oxygen content of water through a long series of reactions in the Winkler test for dissolved oxygen.
Disodium salt is also used in estimating volumetrically the concentrations of certain compounds in solution (hydrogen peroxide, for instance) and in estimating the chlorine content in commercial bleaching powder and water.

Aluminium cation reaction:
Disodium salt is used in analytical chemistry.

Disodium salt can, when heated with a sample containing aluminium cations, produce a white precipitate:
2 Al3+ + 3 S2O2−3 + 3 H2O → 3 SO2 + 3 S + 2 Al(OH)3

Organic chemistry:
Alkylation of Disodium salt gives S-alkylthiosulfates, which are called Bunte salts.
The alkylthiosulfates are susceptible to hydrolysis, affording the thiol.

This reaction is illustrated by one synthesis of thioglycolic acid:
ClCH2CO2H + Na2S2O3 → Na[O3S2CH2CO2H] + NaCl
Na[O3S2CH2CO2H] + H2O → HSCH2CO2H + NaHSO4

Pharmacology and Biochemistry of Disodium salt:

MeSH Pharmacological Classification:

Chelating Agents:
Chemicals that bind to and remove ions from solutions.
Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.

Antioxidants:
Naturally occurring or synthetic substances that inhibit or retard oxidation reactions.
They counteract the damaging effects of oxidation in animal tissues.

Antitubercular Agents:
Drugs used in the treatment of tuberculosis.

They are divided into two main classes:
"First-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.

Stability and Reactivity of Disodium salt:

Reactivity:
Not normally reactive

Chemical Stability:
Normally stable.

Possibility of Hazardous Reactions:
Reacts with acids to form toxic and irritating sulfur dioxide gas.
Reacts with strong oxidizers to cause vigorous exothermic reactions.

Conditions to Avoid:
Avoid elevated temperatures.

Incompatibilities:

Strong oxidizers:
Causes vigorous exothermic reactions.

Acids:
Releases sulfur dioxide and/or hydrogen sulfide gas.

Hazardous Decomposition Products:
Sulfur dioxide gas, hydrogen sulfide gas and sodium sulfide residue.

Handling and Storage of Disodium salt:

Precautions For Safe Handling:
Avoid contact with skin, eyes and clothing.
Do not breathe dust or mist.

Use with adequate ventilation.
Wash thoroughly after handling.

If dissolving and mixing solutions:
With anhydrous material, the reaction is exothermic and the solution will retain heat; with the hydrate (crystal) material, the reaction is endothermic and the solution will cool.

Conditions For Safe Storage, Including Any Incompatibilities:
Store in a cool, dry, well-ventilated area away from acids and oxidizing agents.
Keep container closed when not in use and protect from physical damage.

First Aid Measures of Disodium salt:

SKIN:
Wash skin with plenty of soap and water.
Get medical attention if irritation persists.
Launder contaminated clothing before reuse.

EYES:
Flush eyes immediately with water for at least 15 minutes.
Remove contact lenses if present after the first 5 minutes if you can do so easily and continue flushing.
Get medical attention if irritation occurs and persists.

INHALATION:
Promptly remove to fresh air.
Get immediate medical attention if signs of suffocation, irritation or other symptoms develop.

INGESTION:
If conscious, immediately rinse mouth with water and give 1 glass of water to drink.
Do not induce vomiting unless directed to do so be medical personnel.
Get immediate medical attention.

MOST IMPORTANT SYMPTOMS/EFFECTS, ACUTE AND DELAYED:
May irritate the skin.
May cause irritation to the eyes.

May irritate the respiratory tract.
Reacts with acids to form toxic and irritating sulfur dioxide gas.

INDICATION OF IMMEDIATE MEDICAL ATTENTION AND SPECIAL TREATMENT, IF NEEDED:
Treat symptomatically.

Fire Fighting Measures of Disodium salt:

Suitable (And Unsuitable) Extinguishing Media:
Material is not flammable.
Use extinguishing media appropriate for material in surrounding fire.

Special Protective Equipment And Precautions For Fire-fighting:
Wear NIOSH-approved self-contained breathing apparatus to protect against any release of toxic and/or irritating fumes.
Skin and eye protection should also be provided.
Use water-spray to keep fire-exposed containers cool, and to knock down vapors and gases.

Accidental Release Measures of Disodium salt:

Personal Precautions, Protective Equipment, And Emergency Procedures:
Wear appropriate personal protective equipment.

Environmental Precautions:
Spills and releases may have to be reported to Federal and/or local authorities.

Methods And Materials For Containment And Cleaning Up:
Promptly sweep up material with minimum dusting and shovel into an empty container with a cover.
Clean spill area with plenty of water.

Identifiers of Disodium salt:
CAS Number:
7772-98-7
(pentahydrate): 10102-17-7

ChEBI: CHEBI:132112
ChEMBL: (pentahydrate): ChEMBL2096650
ChemSpider: 22885
ECHA InfoCard: 100.028.970
EC Number: 231-867-5
E number: E539 (acidity regulators, ...)
PubChem CID: 24477
RTECS number: XN6476000

UNII:
L0IYT1O31N
(pentahydrate): HX1032V43M

CompTox Dashboard (EPA): DTXSID9042417
InChI: InChI=1S/2Na.H2O3S2/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2

Key:
AKHNMLFCWUSKQB-UHFFFAOYSA-L
InChI=1/2Na.H2O3S2/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2

Key:
AKHNMLFCWUSKQB-NUQVWONBAM
(pentahydrate): InChI=1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2

Key: PODWXQQNRWNDGD-UHFFFAOYSA-L

SMILES:
[Na+].[Na+].[O-]S([O-])(=O)=S
(pentahydrate): O.O.O.O.O.O=S([O-])([O-])=S.[Na+].[Na+]

CAS: 10102-17-7, 7732-18-5
Molecular Formula: H10Na2O8S2
Molecular Weight (g/mol): 248.172
InChI Key: PODWXQQNRWNDGD-UHFFFAOYSA-L
PubChem CID: 61475
ChEBI: CHEBI:32150
IUPAC Name: disodium;dioxido-oxo-sulfanylidene-$l^{6}-sulfane;pentahydrate
SMILES: O.O.O.O.O.[O-]S(=O)(=S)[O-].[Na+].[Na+]

CAS number: 7772-98-7
EC number: 231-867-5
Hill Formula: Na₂O₃S₂
Molar Mass: 158.10 g/mol
HS Code: 2832 30 00
Quality Level: MQ200

Synonyms: Sodium thiosulfate
Linear Formula: Na2S2O3
CAS Number: 7772-98-7
Molecular Weight: 158.11

Properties of Disodium salt:
Chemical formula: Na2S2O3
Molar mass: 158.11 g/mol (anhydrous)
248.18 g/mol (pentahydrate)
Appearance: White crystals
Odor: Odorless
Density: 1.667 g/cm3
Melting point: 48.3 °C (118.9 °F; 321.4 K) (pentahydrate)
Boiling point: 100 °C (212 °F; 373 K) (pentahydrate, - 5H2O decomposition)
Solubility in water: 70.1 g/100 mL (20 °C)
231 g/100 mL (100 °C)
Solubility: negligible in alcohol
Refractive index (nD): 1.489

Density: 1.667 g/cm3 (20 °C)
Melting Point: 48 °C
pH value: 6.0 - 9.5 (50 g/l, H₂O, 20 °C)
Bulk density: 1350 kg/m3
Solubility: 701 g/l

Molecular Weight: 158.11 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 157.90842477 g/mol
Monoisotopic Mass: 157.90842477 g/mol
Topological Polar Surface Area: 104Ų
Heavy Atom Count: 7
Complexity: 82.6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Specifications of Disodium salt:
Assay (iodometric): ≥ 97.0 %
Identity: passes test
pH-value (5 %; water): 6.0 - 9.5
Sulphide (S): ≤ 0.002 %
Fe (Iron): ≤ 0.005 %
Heavy metals (as Pb): ≤ 0.005 %

Boiling Point: 100°C
Melting Point: 48.3°C
Physical Form: Liquid
Quantity: 1 L
Solubility Information: Soluble in water
Formula Weight: 248.18g/mol
Concentration or Composition (by Analyte or Components): 0.1mol/L
Density: 1.00g/mL
Chemical Name or Material: Sodium Thiosulfate Pentahydrate

Structure of Disodium salt:
Crystal structure: monoclinic

Related compounds of Disodium salt:

Other cations:
Thiosulfuric acid
Lithium thiosulfate
Potassium thiosulfate

Names of Disodium salt:

IUPAC name:
Sodium thiosulfate

Other names:
Sodium hyposulphite
Hyposulphite of soda
Hypo
DISODIUM SULFOACETATE
DISODIUM TARTRATE, N° CAS : 868-18-8. Nom INCI : DISODIUM TARTRATE. Nom chimique : Butanedioic Acid, 2,3-dihydroxy-, disodium Salt, N° EINECS/ELINCS : 212-773-3. Ses fonctions (INCI) : Régulateur de pH : Stabilise le pH des cosmétiques
DISODIUM TARTRATE
Sodium Phosphate Dibasic Dodecahydrate; Disodium hydrogenphosphate Dodecahydrate; cas no: 10039-32-4
DISODIUM TARTRATE
Disodium tartrate (Na2C4H4O6) is a salt used as an emulsifier and a binding agent in food products such as jellies, margarine, and sausage casings.
As a food additive, Disodium tartrate is known by the E number E335.
Because Disodium tartrate crystal structure captures a very precise amount of water, Disodium tartrate is also a common primary standard for Karl Fischer titration, a common technique to assay water content.

CAS Number: 6106-24-7
EC Number: 212-773-3
Hill Formula: Na2C4H4O6
Molar Mass: 230.08 g/mol

Disodium tartrate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 to < 10 tonnes per annum.
Disodium tartrate is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Disodium tartrate is the organic sodium salt that is the disodium salt of L-tartaric acid.
Disodium tartrate has a role as a food emulsifier.
Disodium tartrate contains a L-tartrate(2-).

Disodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals.
Disodium tartrate is obtained as a byproduct of wine manufacturing.

Disodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient.
Disodium tartrate acts as an emulsifier and pH control agent in food products.
Disodium tartrate is commonly used as an emulsifier in cheese/cheese spread products and is not to exceed 4% concentration, according to Health Canada regulations.

Disodium tartrate belongs to the class of organic compounds known as beta hydroxy acids and derivatives.
Beta hydroxy acids and derivatives are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom.
Based on a literature review very few articles have been published on Disodium tartrate.

Disodium tartrate is a solid standard with water content of 15.66% determined by the technique of loss on drying at 150°C.
Disodium tartrate preparation from high-purity reagents and analysis is completed in an ISO/IEC 17025 and ISO 17034 accredited calibration laboratory.

Disodium tartrate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.

American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement.

Disodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals.
Disodium tartrate is obtained as a byproduct of wine manufacturing.

Disodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient.
Disodium tartrate acts as an emulsifier and pH control agent in food products.

This monograph for Disodium tartrate provides, in addition to common physical constants, a general description including typical appearance, applications, change in state (approximate), and aqueous solubility.
The monograph also details the following specifications and corresponding tests for verifying that a substance meets ACS Reagent Grade specifications including: Assay, Loss on Drying, pH of a 5% Solution at 25.0 °C, Insoluble Matter, Chloride, Phosphate, Sulfate, Ammonium, Calcium, Heavy Metals, and Iron.

Disodium tartrate is a Acid phosphatase inhibitor, is a sodium salt used in buffers for molecular biology and cell culture applications.
Increases the rate of colchicine binding to tubulin.

Disodium tartrate is a crystalline salt of tartaric acid and sodium.
Disodium tartrate is a white powder that is soluble in water, alcohols, and ethers.

Disodium tartrate has been shown to be thermodynamically stable up to 350 °C, with a phase transition temperature of 230 °C.
Disodium tartrate has been used in the synthesis of polymaleic acid and other biological products.

Disodium tartrate was also shown to have an effect on the absorption of radiation by water vapor when Disodium tartrate was mixed with sodium carbonate.
The melting point of Disodium tartrate is about 195 °C, which means Disodium tartrate will decompose at temperatures above this value.

Disodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals.
Disodium tartrate is obtained as a byproduct of wine manufacturing.

Disodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient.
Disodium tartrate acts as an emulsifier and pH control agent in food products.

Disodium tartrate is commonly used as an emulsifier in cheese/cheese spread products and is not to exceed 4% concentration, according to Health Canada regulations.

Uses of Disodium Tartrate:
Disodium tartrate is used for standardizing Karl Fischer reagent, as a pharmaceutic aid (sequestering agent), and cathartic.
Disodium tartrate is used as an emulsifier, pH control agent, and sequestrant for foods.

Permitted for use as an inert ingredient in non-food pesticide products.
Disodium tartrate is used for standardizing Karl Fischer reagent, as a pharmaceutic aid (sequestering agent), and cathartic.

Disodium tartrate a naturally occurring chemical compound found in berries, grapes and various wines.
Disodium tartrate provides antioxidant properties and contributes to the sour taste within these products.

Disodium tartrate dibasic dihydrate may be used in the preparation of solid-state M–L compounds (M = bivalent metal ions ie., Mn, Fe, Co, Ni, Cu, Zn; L = tartrate).
Disodium tartrate may also be used in the preparation of copper (II) and cobalt (II) tartrate complexes by reacting with the corresponding metal salts.
These complexes can undergo thermal decomposition to form Cu and Co metal oxide nanoparticles.

Widespread uses by professional workers:
Disodium tartrate is used in the following products: laboratory chemicals.
Disodium tartrate is used in the following areas: scientific research and development.
Other release to the environment of Disodium tartrate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Uses at industrial sites:
Disodium tartrate is used in the following products: laboratory chemicals.
Disodium tartrate is used for the manufacture of: chemicals.
Release to the environment of Disodium tartrate can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

Industry Uses:
Cleaning agent

General Manufacturing Information of Disodium Tartrate:

Industry Processing Sectors:
Computer and Electronic Product Manufacturing
Electrical Equipment, Appliance, and Component Manufacturing
Fabricated Metal Product Manufacturing
Machinery Manufacturing
Transportation Equipment Manufacturing

Action Mechanism of Disodium Tartrate:
Disodium tartrate is a white, crystalline powder, used as an emulsifier and a binding agent.
Disodium tartrate can be used in jellies, cheeses, sausage casings and any foods which contain fats or oils.

Purification Methods of Disodium Tartrate:
Disodium tartrate crystallises from warm dilute aqueous NaOH on cooling.

Identifiers of Disodium Tartrate:
CAS Number:
868-18-8 (anhydrous)
6106-24-7 (dihydrate)
ChemSpider: 12786
PubChem CID: 13355
UNII: QTO9JB4MDD
DIA7C37AOW (dihydrate)
CompTox Dashboard (EPA): DTXSID1028021
InChI: InChI=1S/C4H6O6.2Na/c5-1(3(7)8)2(6)4(9)10;;/h1-2,5-6H,(H,7,8)(H,9,10);;/q;2*+1/p-2
Key: HELHAJAZNSDZJO-UHFFFAOYSA-L
InChI=1S/C4H6O6.2Na/c5-1(3(7)8)2(6)4(9)10;;/h1-2,5-6H,(H,7,8)(H,9,10);;/q;2*+1/p-2
Key: HELHAJAZNSDZJO-NUQVWONBAO
Key: HELHAJAZNSDZJO-UHFFFAOYSA-L
SMILES: [Na+].[Na+].O=C([O-])C(O)C(O)C([O-])=O

CAS: 6106-24-7
Molecular Formula: C4H10Na2O8
Molecular Weight (g/mol): 232.096
MDL Number: MFCD00150035
InChI Key: YAPIZISBZUXUIH-DGFHWNFOSA-N
PubChem CID: 131855972
IUPAC Name: (2R,3R)-2,3-dihydroxybutanedioic acid;sodium;dihydrate
SMILES: C(C(C(=O)O)O)(C(=O)O)O.O.O.[Na].[Na]

Synonyms: L-(+)-Tartaric acid disodium salt, Disodium tartrate dihydrate, Sodium tartrate dihydrate
Empirical Formula (Hill Notation): C4H4Na2O6 · 2H2O
CAS Number: 6106-24-7
Molecular Weight: 230.08
EC Number: 212-773-3

CAS number: 6106-24-7
EC number: 212-773-3
Hill Formula: C₄H₄Na₂O₆ * 2H₂O
Molar Mass: 230.08 g/mol
HS Code: 2918 13 00

Properties of Disodium Tartrate:
Chemical formula: C4H4Na2O6 (anhydrous)
C4H8Na2O8 (dihydrate)
Molar mass: 194.051 g/mol (anhydrous)
230.082 g/mol (dihydrate)
Appearance: white crystals
Density: 1.545 g/cm3 (dihydrate)
Solubility in water: soluble
Solubility: insoluble in ethanol

Density: 1.820 g/cm3 (20 °C)
pH value: 7.0 - 9 (50 g/l, H₂O, 20 °C)
Bulk density: 460 kg/m3
Solubility: 290 g/l

Molecular Weight: 194.05
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 1
Exact Mass: 193.98032641
Monoisotopic Mass: 193.98032641
Topological Polar Surface Area: 121 Ų
Heavy Atom Count: 12
Complexity: 123
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 2
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Specifications of Disodium Tartrate:
Assay (perchloric acid titration): ≥ 99.5 %
pH-value (5 %; water): 7.0 - 8.0
Chloride (Cl): ≤ 0.0005 %
Phosphate (PO₄): ≤ 0.0005 %
Sulfate (SO₄): ≤ 0.002 %
Total nitrogen (N): ≤ 0.002 %
Heavy metals (as Pb): ≤ 0.0005 %
Ca (Calcium): ≤ 0.005 %
Fe (Iron): ≤ 0.0005 %

Color: White
Quantity: 25 g
Formula Weight: 194.05
Percent Purity: ≥98.0% (T)
Physical Form: Crystalline Powder
Chemical Name or Material: Disodium L-(+)-Tartrate Dihydrate

Names of Disodium Tartrate:

Regulatory process names:
Bisodium tartrate
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, disodium salt
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, sodium salt (1:2)
Butanedioic acid, 2,3-dihydroxy- (R-(R*,R*))-, disodium salt
Butanedioic acid, 2,3-dihydroxy- (theta-(theta,theta))-, disodium salt
Butanedioic acid, 2,3-dihydroxy-(R-(R*,R*))-, disodium salt (9CI)
Disodium 2,3-dihydroxybutanedioate, (R-(R*,R*))-
Disodium L-(+)-tartrate
Disodium tartrate
Disodium tartrate
disodium tartrate
Natrium (RR)-tartrat
Sal tartar
Sodium L-(+)-tartrate
Sodium tartrate
Tartaric acid, disodium salt

IUPAC names:
2,3-dihydroxybutanedioic acid sodium salt (1:2)
disodium (2R,3R)-2,3-dihydroxybutanedioate
disodium 2,3-dihydroxybutanedioate
disodium tartarate
disodium tartrate
DISODIUM TARTRATE, ANHYDROUS
disodium(2R,3R)-2,3-dihydroxybutanedioate
Sodio Tartrato 2-hidrato
Sodium tartrate
disodium (2R,3R)-2,3-dihydroxybutanedioate

Other names:
Sal tartar
Disodium tartrate
Bisodium tartrate
Sodium l-(+)-tartrate
E335

Other identifiers:
133-48-2
17990-54-4
58114-54-8
6106-24-7
868-18-8

Synonyms of Disodium Tartrate:
Sodium L-tartrate
Disodium L-(+)-tartrate
Bisodium tartrate
Sal tartar
868-18-8
Disodium tartrate
TARTARIC ACID, DISODIUM SALT
Sodium L-(+)-tartrate
disodium L-tartrate
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, disodium salt
QTO9JB4MDD
Disodium (+/-)-tartrate
Disodium salt of L-(+)-tartaric acid
WDT27AD907
disodium (2R,3R)-2,3-dihydroxybutanedioate
CHEBI:63017
Sodium (2R,3R)-2,3-dihydroxysuccinate
Butanedioic acid, 2,3-dihydroxy-, disodium salt, (2R,3R)-rel-
Sodium (2R,3R)-2,3-dihydroxysuccinate(x:1)
Sodium tartrate [NF]
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, sodium salt (1:2)
L-(+)-Tartaric acid disodium salt
Natrium (RR)-tartrat
51307-92-7
Sodiumtartrate
CCRIS 7318
sodium dl-tartrate
Disodium (2RS,3SR)-tartrate
EINECS 212-773-3
sodium L(+)-tartrate
UNII-QTO9JB4MDD
6106-24-7
UNII-WDT27AD907
SODIUM (+)-TARTRATE
SODIUM DEXTRO-TARTRATE
SODIUM TARTRATE [II]
SODIUM TARTRATE [MI]
SCHEMBL456386
SODIUM TARTRATE [FCC]
Disodium 2,3-dihydroxybutanedioate, (R-(R*,R*))-
SODIUM TARTRATE RACEMATE
INS NO.335(II)
Butanedioic acid, 2,3-dihydroxy-, sodium salt (1:2), (2R,3R)-rel-
CHEMBL2107781
DISODIUM TARTRATE [INCI]
DTXSID1028021
DTXSID2057861
SODIUM TARTRATE [MART.]
INS-335(II)
SODIUM TARTRATE [WHO-DD]
l(+)-tartaric acid disodium salt
SODIUM TARTRATE, L (+)-
Butanedioic acid, 2,3-dihydroxy- (R-(R*,R*))-, disodium salt
Butanedioic acid, 2,3-dihydroxy-(R-(R*,R*))-, disodium salt
E-335(II)
AKOS006240046
Butanedioic acid, 2,3-dihydroxy- (theta-(theta,theta))-, disodium salt
DB13707
Sodium(2R,3R)-2,3-dihydroxysuccinate
disodium (2R,3R)-2,3-dihydroxysuccinate
D4027
E78255
EN300-7817107
disodium (R-(R*,R*))-2,3-dihydroxybutanedioate
DISODIUM (+)-2,3-DIHYDROXYBUTANEDIOIC ACID
Q27132338
(R-(R*,R*))-2,3-dihydroxybutanedioic acid, disodium salt
BUTANEDIOIC ACID, 2,3-DIHYDROXY-, DISODIUM SALT, (R*,R*)-
Butanedioic acid, 2,3-dihydroxy-, disodium salt, (R*,R*)-(+-)-
BUTANEDIOIC ACID, 2,3-DIHYDROXY-, DISODIUM SALT, (R*,R*)-(+/-)-
DISODIUMPHOSPHATE 
Alkylol ammonium salt of a copolymer with acidic groups; BYK
DISODYUM LAURET SULFOSUKSİNAT %40
Yumuşak, cilde zarar vermeyen kozmetik ve temizlik ürünlerinde, bebe şampuanlarında, banyo köpüklerinde kullanılan anyonik yüzey aktif.
DISOIDUM DIHYDROGEN PYROPHOSPHATE
Disodium dihydrogen pyrophosphate, also known as Sodium acid pyrophosphate, is a white, water soluble solid that has many applications in the food industry.
Disodium dihydrogen pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.
Disodium dihydrogen pyrophosphate is a popular leavening agent found in baking powders.

CAS Number: 7758-16-9
EC Number: 231-835-0
Molecular Formula: H5NaO7P2
Molcular Weight: 201.97

Synonyms: Disodium dihydrogen diphosphate, Diphosphoric acid, disodium salt, Disodium dihydrogen pyrophosphate, Disodium diphosphate, Sodium acid pyrophosphate, SAPP, Disodium, Pyrophosphate, Disodium Diphosphate, Disodium Dihydrogen Diphosphate, Disodium Dihydrogen Pyrophosphate, Diphosphoric Acid, Disodium Salt, Pyrophosphoric Acid, Disodium Salt, Disodium diphosphate, Disodium pytophosphate, Disodium dihydroge3 disodium salt, H5WVD9LZUD, Sodium pyrophosphate (Na2H2P2O7), Diphosphoric acid, sodium salt (1:2) , Dinatriumpyrophosphat, Sodium polyphosphates, Natrium polyphosphat, Sodium polyphosphatium phosphate, Natrium polyphosphatium DS42_Sodium Polyphosphate, dihydrogendiphosphate, DSSTox_RID_78658, DSSTox_GSID_28842 ,2Na.H2P2O7, Sodium dihydrogen pyrophosphate, Sodium polyphosphate, amorphous, CHEMBL3184949, DTXSID_GSID_28842, LS-2432, NCGC00258367-01, [hydroxy(oxido)phosphoryl] hydrogen phosphate, Sodium acid pyrophosphate, SAPP, Diphosphoric acid, disodium salt, Disodium acid pyrophosphate, Disodium dihydrogen diphosphate, Disodium dihydrogen pyrophosphate, Disodium diphosphate, Pyrophosphoric acid, disodium salt, Sodium pyrophosphate dibasic, disodium dihydrogen pyrophosphate, pyrophosphoric acid, disodium salt (8ci), sapp 40, disodiumdiphosphate, sapp, sodium acid pyrophosphate(sapp),sodium acid pyrophosphate (sapp), dspp, dihydrogen disodium pyrophosphate, disodium pyrophosphate (na2h2p2o7), sodiumpyrophosphate,acid, dinatriumpyrophosphat, disodium pytophospha, disodium pyrophosphate, disodium dihydrogen diphosphate, disodium pytophosphate, diphosphoricacid, disodium salt (9ci), sodiumpyrophosphate (na2h2p2o7) (6ci), sapp 28, sapp-rd 1, disodium dihydrogendiphosphate (na2h2p2o7), sodium hydrogen phosphate (na2h2p2o7), Disodium dihydrogen pyrophosphate, SAPP, E450, 7758-16-9, Disodium diphosphate, Sodium acid pyrophosphate, Disodium dihydrogen pyrophosphate, DISODIUM PYROPHOSPHATE, H5WVD9LZUD, disodium;[hydroxy(oxido)phosphoryl] hydrogen phosphate, MFCD00014246, Disodium acid pyrophosphate, Dinatriumpyrophosphat, Disodiumpytophosphate, Dinatriumpyrophosphat [German], Disodium dihydrogen diphosphate, Disodium dihydrogenpyrophosphate, HSDB 377, Pyrophosphoric acid, disodium salt, UNII-H5WVD9LZUD, Sodium pyrophosphate (Na2H2P2O7), EINECS 231-835-0, Sodium diphosphate dibasic, disodium hydrogen (hydrogen phosphonatooxy)phosphonate, Grahamsches salz, Glassy sodium phosphate, DSSTox_CID_8842, sodium dihydrogendiphosphate, EC 231-835-0, DSSTox_RID_78658, DSSTox_GSID_28842, SODIUMACIDPYROPHOSPHATE, Sodium pyrophosphate, dibasic, Sodium dihydrogen pyrophosphate, CHEMBL3184949, EINECS 272-808-3, Tox21_200813, DISODIUM PYROPHOSPHATE [HSDB], DISODIUM PYROPHOSPHATE [INCI], DISODIUM PYROPHOSPHATE [VANDF], AKOS015916169, AKOS024418779, SODIUM ACID PYROPHOSPHATE [MI], Diphosphoric acid, sodium salt (1:2), SODIUM ACID PYROPHOSPHATE [FCC], NCGC00258367-01, SODIUM ACID PYROPHOSPHATE [VANDF], CAS-68915-31-1

Disodium dihydrogen pyrophosphate is a food-grade chemical compound that belongs to the group of sodium phosphates.
Disodium dihydrogen pyrophosphate is a white, crystalline powder or granular material with various applications in the food industry.

Disodium dihydrogen pyrophosphate is recognized as a food additive and is commonly used for its leavening, buffering, and emulsifying properties.
Disodium dihydrogen pyrophosphate serves as a buffering, chelating and leavening agent.

Disodium dihydrogen pyrophosphate encodes a integral membrane protein.
Disodium dihydrogen pyrophosphate is a soluble protein generated by sequential cleavage with α and γ secretase.

Disodium dihydrogen pyrophosphate, also known as Sodium acid pyrophosphate, is an inorganic compound composed of sodium cation and pyrophosphate anion.
Disodium dihydrogen pyrophosphate is a white, water-soluble solid, commonly used as a buffer and chelating agent and has many applications in food processing industry.

Disodium dihydrogen pyrophosphate is a white monoclinic crystal powder.
Disodium dihydrogen pyrophosphates relative density is 1.86.

Disodium dihydrogen pyrophosphate is soluble in water, insoluble in alcohol.
Disodium dihydrogen pyrophosphate hydrolyzes to orthophosphate when heated in acid medium.

Disodium dihydrogen pyrophosphate is hygroscopic, forms hexahydrate in damp air, and decomposes to metaphosphate at above 220℃.
The leavening acid, Disodium dihydrogen pyrophosphate is an important component of double acting baking powder as well as self rising flour.

Disodium dihydrogen pyrophosphate reacts in stages and is desirable in baking applications for its slow action.
Disodium dihydrogen pyrophosphate or Sodium acid pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.

Disodium dihydrogen pyrophosphate is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.
When crystallized from water, Disodium dihydrogen pyrophosphate forms a hexahydrate, but Disodium dihydrogen pyrophosphate dehydrates above room temperature.

Disodium dihydrogen pyrophosphate is a polyvalent anion with a high affinity for polyvalent cations.
Disodium dihydrogen pyrophosphate, also known as Disodium pyrophosphate, Sodium acid pyrophosphate, is white crystalline powder, which has the relative density of 1.864 and can decompose into sodium metaphosphate when Disodium dihydrogen pyrophosphate is heated above 220℃.

Disodium dihydrogen pyrophosphate is easily soluble in water and can form chelates with Cu2+ and Fe2+.
The aqueous solution can be hydrolyzed to phosphoric acid by heating with dilute sulfuric acid or dilute mineral acid.

Disodium dihydrogen pyrophosphate is usually used in food processing industry.
Disodium dihydrogen pyrophosphate, or Disodium pyrophosphate, its food grade is commonly used with sodium bicarbonate as a leavening agent in bakery products; also, Disodium dihydrogen pyrophosphate maintains the color in processed potatoes and also prevents struvite crystal in canned seafood.

The European food additive number for Disodium dihydrogen pyrophosphate is E450(i).
Generally, Disodium dihydrogen pyrophosphate is vegan and gluten free.

Disodium dihydrogen pyrophosphate also known as Di-sodium Di-phosphate is an inorganic compound of sodium and pyrophosphate.
Disodium dihydrogen pyrophosphate is white and soluble in water.

Disodium dihydrogen pyrophosphate is manufactured with double drying process like other Pyrophosphates due to heating needed at a high temperature.
Disodium dihydrogen pyrophosphate is solubility in water is 13g Na2H2P2O7/100g H2O at 20 °C, and 20g at 80°C.

The pH of a 1% aqueous solution is 4.1. The usual commercial product is the anhydrous, nonhygroscopic salt in powder form.
The hexahydrate, Na2H2P2O7.6H2O, d 1.85, crystallizes from aqueous solution below 27 °C.

Above this temperature, Disodium dihydrogen pyrophosphate is converted to the anhydrous form.
Disodium dihydrogen pyrophosphate is used as a (tropically stable) acid carrier in baking powder, for improvement of flow properties in flour, for pH regulation, and in dental care products for prevention of tartar formation.

Disodium dihydrogen pyrophosphate is available in a variety of grades that affect the speed of its action.
Because the resulting phosphate residue has an off-taste, Disodium dihydrogen pyrophosphate is usually used in very sweet cakes which mask the off-taste.

Disodium dihydrogen pyrophosphate is manufactured by partially neutralizing food grade phosphoric acid with sodium hydroxide or sodium carbonate to form monosodium phosphate.
Dehydration of monosodium phosphate at 250°C will form Disodium dihydrogen pyrophosphate.

Leavening acids provide air and volume to the baked good structure, but also affect the characteristics of the dough.
Besides reacting with baking soda to produce the gas carbon dioxide, these acids form ionic bonds with the starches and proteins in the dough.

Disodium dihydrogen pyrophosphate dissolves readily to form the anion pyrophosphate which interacts with the proteins in a baked good system to provide a moist texture.
Also, Disodium dihydrogen pyrophosphate provides a buffer system for the dough in the pH range 7.3-7.5, which influences the color of the baked product.

Disodium dihydrogen pyrophosphate is a white, crystalline powder or granular substance.
Disodium dihydrogen pyrophosphate is a sodium salt of pyrophosphoric acid and is commonly used as a food additive and in various industrial applications.

Disodium dihydrogen pyrophosphate has unique chemical properties that make Disodium dihydrogen pyrophosphate versatile in different processes.
Disodium dihydrogen pyrophosphate acts as a leavening agent in food production, helping dough rise and creating a light texture in baked goods.
In addition to its culinary uses, Disodium dihydrogen pyrophosphate is utilized as a buffering agent, stabilizer, and emulsifier in food processing.

Disodium dihydrogen pyrophosphate also finds application as a corrosion inhibitor, pH adjuster, and chelating agent in various industries.
Disodium dihydrogen pyrophosphate is a slow leavening acid and Disodium dihydrogen pyrophosphate may contain a suitable aluminum and/or calcium salt to control the rate of reaction.
Disodium dihydrogen pyrophosphate and other sodium and potassium polyphosphates are widely used in food processing; in the E number scheme, they are collectively designated as E450, with the disodium form designated as E450(a).

In the United States, Disodium dihydrogen pyrophosphate is classified as generally recognized as safe (GRAS) for food use.
In canned seafood, Disodium dihydrogen pyrophosphate is used to maintain color and reduce purge[clarification needed] during retorting.
Retorting achieves microbial stability with heat.

Disodium dihydrogen pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.
In baking powder, Disodium dihydrogen pyrophosphate is often labeled as food additive E450.
In cured meats, Disodium dihydrogen pyrophosphate speeds the conversion of sodium nitrite to nitrite (NO2−) by forming the nitrous acid (HONO) intermediate,[clarification needed] and can improve water-holding capacity.

Disodium dihydrogen pyrophosphate is also found in frozen hash browns and other potato products, where Disodium dihydrogen pyrophosphate is used to keep the color of the potatoes from darkening.
Disodium dihydrogen pyrophosphate can leave a slightly bitter aftertaste in some products, but "the SAPP taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings."

Disodium dihydrogen pyrophosphate has limited direct uses in water treatment processes.
Disodium dihydrogen pyrophosphate can indirectly contribute to certain aspects of water treatment.

Disodium dihydrogen pyrophosphate is sometimes employed as a pH adjuster and buffering agent in water treatment applications where precise pH control is necessary.
Disodium dihydrogen pyrophosphate can help stabilize and maintain the desired pH range, optimizing treatment processes.

Disodium dihydrogen pyrophosphate can act as a sequestering agent, chelating metal ions and preventing their precipitation or interference with water treatment chemicals.
Its ability to bind with metal ions aids in minimizing scaling and maintaining the efficiency of water treatment equipment.

Disodium dihydrogen pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.
Disodium dihydrogen pyrophosphate is a white, water-soluble that serves as a buffering and chelating agent, with many applications in the food industry.

When crystallised from water, Disodium dihydrogen pyrophosphate forms hexahydrate, but Disodium dihydrogen pyrophosphate dehydrates above room temperature.
Disodium dihydrogen pyrophosphate is a polyvalent anion with a high affinity for polyvalent cations.

Disodium dihydrogen pyrophosphate is a popular leavening agent found in baking powders.
Disodium dihydrogen pyrophosphate combines with sodium bicarbonate to release carbon dioxide.

Disodium dihydrogen pyrophosphate is available in a variety of grades that effect the speed of its action.
Because the resulting phosphate residue has an off-taste, Disodium dihydrogen pyrophosphate is usually used in very sweet cakes which mask the taste.

Disodium dihydrogen pyrophosphate is designated in the USA as generally recognized as safe for food use.
Disodium dihydrogen pyrophosphate is used in canned seafood to maintain color and reduce purge during retorting.

Retorting achieves microbial stability with heat.
Disodium dihydrogen pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.

Disodium dihydrogen pyrophosphate is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Disodium dihydrogen pyrophosphate.
Disodium dihydrogen pyrophosphate is used as an acidulant, buffering agent, and leavening agent.
Disodium dihydrogen pyrophosphate has a dough reaction rate of 24 – 28.

Disodium dihydrogen pyrophosphate is an all-purpose phosphate commonly used in prepared mixes, commercial baking powders, and cake doughnut mixes.
Disodium dihydrogen pyrophosphate and other sodium and potassium polyphosphates are widely used in food processing; in the E number scheme, they are collectively designated as E450, with the disodium form designated as E450(a).

In the United States, Disodium dihydrogen pyrophosphate is classified as generally recognized as safe (GRAS) for food use.
In canned seafood, Disodium dihydrogen pyrophosphate is used to maintain color and reduce purge[clarification needed] during retorting.

Retorting achieves microbial stability with heat.
Disodium dihydrogen pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.

In baking powder, Disodium dihydrogen pyrophosphate is often labeled as food additive E450.
In cured meats, Disodium dihydrogen pyrophosphate speeds the conversion of sodium nitrite to nitrite (NO2−) by forming the nitrous acid (HONO) intermediate,[clarification needed] and can improve water-holding capacity.

Disodium dihydrogen pyrophosphate is also found in frozen hash browns and other potato products, where Disodium dihydrogen pyrophosphate is used to keep the color of the potatoes from darkening.
Disodium dihydrogen pyrophosphate can leave a slightly bitter aftertaste in some products, but "the SAPP taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings.
Disodium dihydrogen pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.

As a leavening acid which combines with baking soda to release carbon dioxide to improve the texture and volume of baked goods.
As a chelating agent to chelate iron to prevent discoloration in processed potato.
Amyloid precursor protein α is an α-secretase-cleaved soluble protein that has been shown to have neuroprotective properties.

Disodium dihydrogen pyrophosphate is derived from amyloid precursor protein.
The protein consists of 612 amino acids.
Several G protein-coupled receptors are known to activate α-secretase-dependent processing of APP.

Disodium dihydrogen pyrophosphate has neuroprotective, neurogenic and neurotrophic functions.
Amyloid precursor protein a also stimulates gene expression and protein expression.
In leather treatment, Disodium dihydrogen pyrophosphate can be used to remove iron stains on hides during processing.

Disodium dihydrogen pyrophosphate can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.
When added to scalding water, Disodium dihydrogen pyrophosphate facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.
Disodium dihydrogen pyrophosphate in petroleum production, Disodium dihydrogen pyrophosphate can be used as a dispersant in oil well drilling muds.

Disodium dihydrogen pyrophosphate can also be found in frozen hash browns and other potato products, where Disodium dihydrogen pyrophosphate is used to keep the color of the potatoes from darkening.
Disodium dihydrogen pyrophosphate is a sodium salt of pyrophosphoric acid, and its chemical formula is Na2H2P2O7.

Disodium dihydrogen pyrophosphate in the food industry is as a leavening agent.
Disodium dihydrogen pyrophosphate releases carbon dioxide gas when Disodium dihydrogen pyrophosphate reacts with alkalis, such as baking soda (sodium bicarbonate), when exposed to moisture and heat.

This gas production causes dough or batter to rise, resulting in baked goods with a lighter texture.
Disodium dihydrogen pyrophosphate is often used in baking powder formulations to provide a delayed or slow-acting leavening effect.

Disodium dihydrogen pyrophosphate acts as a pH buffer in various food products, helping to control and stabilize their acidity or alkalinity.
Disodium dihydrogen pyrophosphate is used in processed foods to maintain the desired pH level, preventing changes in flavor, color, and texture.

Disodium dihydrogen pyrophosphate can also serve as an emulsifying agent in certain food products, helping to blend ingredients that would not naturally mix together, such as oil and water.
Disodium dihydrogen pyrophosphate is commonly used in a variety of food products, including baked goods like cakes, muffins, and pancakes, as well as in pancakes, waffles, and other batter-based items.

Disodium dihydrogen pyrophosphate is also used in certain dairy products, such as processed cheeses, to help improve their melting and texture.
Disodium dihydrogen pyrophosphate may be used in meat products as a pH regulator, in canned seafood to maintain product quality, and in potato products like French fries to prevent discoloration.

Uses of Disodium dihydrogen pyrophosphate:
Disodium dihydrogen pyrophosphate is used Buffering Agents, Food & Beverage, Food Additives, Levelling Agents, Oil Field Services, Chelants, and Leather.

Food uses:
Disodium dihydrogen pyrophosphate is a popular leavening agent found in baking powders.

Disodium dihydrogen pyrophosphate combines with sodium bicarbonate to release carbon dioxide:
Na2H2P2O7 + NaHCO3 → Na3HP2O7 + CO2 + H2O

Disodium dihydrogen pyrophosphate is available in a variety of grades that affect the speed of its action.
Because the resulting phosphate residue has an off-taste, Disodium dihydrogen pyrophosphate is usually used in very sweet cakes which mask the off-taste.

Disodium dihydrogen pyrophosphate used as buffering agent, leavening agent, sequestrant agent.
Disodium dihydrogen pyrophosphate can be used in canned food, ham, meat,baking powder and so on.

Disodium dihydrogen pyrophosphate in baking powder, New Zealand, 1950s
Disodium dihydrogen pyrophosphate and other sodium and potassium polyphosphates are widely used in food processing.

In canned seafood, Disodium dihydrogen pyrophosphate is used to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.

Disodium dihydrogen pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.
Disodium dihydrogen pyrophosphate is used as a tartar control agent in toothpastes.
Disodium dihydrogen pyrophosphate can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.

In baking powder, Disodium dihydrogen pyrophosphate is often labeled as food additive E450.
In cured meats, Disodium dihydrogen pyrophosphate speeds the conversion of sodium nitrite to nitrite (NO2−) by forming the nitrous acid (HONO) intermediate, and can improve water-holding capacity.

Disodium dihydrogen pyrophosphate is also found in frozen hash browns and other potato products, where Disodium dihydrogen pyrophosphate is used to keep the color of the potatoes from darkening.

Disodium dihydrogen pyrophosphate can stabilize hydrogen peroxide solutions against reduction.
Disodium dihydrogen pyrophosphate can leave a slightly bitter aftertaste in some products, but "the Disodium dihydrogen pyrophosphate taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings."
In leather treatment, Disodium dihydrogen pyrophosphate can be used to remove iron stains on hides during processing.

When added to scalding water, Disodium dihydrogen pyrophosphate facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.
In petroleum production, Disodium dihydrogen pyrophosphate can be used as a dispersant in oil well drilling muds.
Disodium dihydrogen pyrophosphate is used in cat foods as a palatability additive.

Because Disodium dihydrogen pyrophosphate is slow acting and does not react quickly with baking soda, Disodium dihydrogen pyrophosphate is the most commonly used leavening acid for self rising flour for the home baker.
Per 21 C.F.R. § 137.180(a) 2018, self rising flour must contain enough leavening acid to neutralize the baking soda, but the combination of both can not exceed 4.5 parts per 100 parts flour.

The quantity of leavening acid needed hinges on Disodium dihydrogen pyrophosphate's neutralizing value (NV) which is defined as the quantity of baking soda needed to neutralize 100 parts of leavening acid.
For Disodium dihydrogen pyrophosphate, NV is 70.

Because Disodium dihydrogen pyrophosphate can have a slight bitter taste, Disodium dihydrogen pyrophosphate’s important to use sufficient baking soda in applications as well as use this leavening acid in combination with sugary goods such as doughnuts and cakes.

In canned tuna, Disodium dihydrogen pyrophosphate prevents harmless struvite crystals from forming.
Cake doughnuts are an important application for Disodium dihydrogen pyrophosphate, where initial gas production is necessary for buoyancy in a fryer system.
Also, Disodium dihydrogen pyrophosphate is useful for cakes, where initial gas production is necessary for consistency of pan fill.

Other non-bakery food applications of Disodium dihydrogen pyrophosphate include use as a chelating agent for processed potatoes, an emulsifying agent in cheeses and a curing accelerator in processed meats.
Disodium dihydrogen pyrophosphate can be used as a leavening chemical for bread to help Disodium dihydrogen pyrophosphate rise.

Disodium dihydrogen pyrophosphate's used in sausage to enhance flavor and color.
In french fries, the chemical reduces levels of a carcinogen called acrylamide.

Disodium dihydrogen pyrophosphate also prevents discoloration in potatoes and sugar syrups.
Disodium dihydrogen pyrophosphate is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.
Disodium dihydrogen pyrophosphate is widely used as thinner in oil well drilling muds and even as an industrial cleaner.

Disodium dihydrogen pyrophosphate's key advantages are:
Aids in the removal of calcium and reduces pH in cement contaminated fluids.
At low concentration levels, Disodium dihydrogen pyrophosphate is fast-acting and effective.

Aids break up clay particles and sediments, which enables them to be extracted during oil well development.
Disodium dihydrogen pyrophosphate is used in the chemical clean up of fluids which have been contaminated by cement.
Disodium dihydrogen pyrophosphate decreases the viscosity and gel strengths in freshwater drilling fluids.

Disodium dihydrogen pyrophosphate is used as a deflocculant (thinner) in freshwater mud systems.
Disodium dihydrogen pyrophosphate is often used to break up mud rings when water drilling and is also used to thin out cement before cementing casing.

In cementing applications, Disodium dihydrogen pyrophosphate is used for two primary purposes:
Contaminated drilling mud can result in fluid loss, thickening time, and viscosity.
Disodium dihydrogen pyrophosphate is used to disperse and displace drilling muds to avoid mud being affected by cement contamination.

Solids carrying fluid or drilling mud must be removed from the perforation channels and the rock face to allow a good cement bond and complete fill-up of the voids.
Incorporating Disodium dihydrogen pyrophosphate into the spacer will help remove residual muds and provide a cleaner surface to which the cement can bond.

Disodium dihydrogen pyrophosphate is used as an acidulant, buffering agent, coagulant, emulsifying agent, dispersing agent, protein modifier, and sequestrant.
Actively thins out reactive clays.
In non-dairy creamers, Disodium dihydrogen pyrophosphate is added to protect the proteins from heat dehydration, to stabilize the fat emulsion, and to buffer Disodium dihydrogen pyrophosphate.

Processed potatoes are protected from iron-induced darkening when treated with Disodium dihydrogen pyrophosphate.
Addition of Disodium dihydrogen pyrophosphate to albacore tuna during canning decreases or prevents formation of struvite crystals.

Disodium dihydrogen pyrophosphate is used in meat processing to accelerate development of red color in wieners, bologna, and other emulsion-type meat products.
Disodium dihydrogen pyrophosphate can be used as an emulsifying agent during cheese processing to produce a hard, non-melting cheese product.

Disodium dihydrogen pyrophosphate is Baking powder, used in baking and to control the fermenting speed, to increase the producing strength.
Disodium dihydrogen pyrophosphateis used in instant noodles to reduce time after subjecting to water.

Disodium dihydrogen pyrophosphate is also used in biscuits and cakes, to reduce fermenting time, to decrease the destroying, to maintain the clear gaps, finally to extend products storage.
Disodium dihydrogen pyrophosphate is used Vegetables (esp. potatoes) processing.

Disodium dihydrogen pyrophosphate is used Seafood, meat, cheese processing.
Disodium dihydrogen pyrophosphate is speedly fermentation, water retaining agent and quality improver, used in bread, biscuits, meat, aquatic products and so on.

As quality improver, Disodium dihydrogen pyrophosphate enhances complexation,PH value and Ionic strength.
According to rules, Disodium dihydrogen pyrophosphate's max adding quantity is 3.0g/KG in biscuits and 1.0-3.0g/KG in bread.

Disodium dihydrogen pyrophosphate is reactive not only with sodium bicarbonate, but also with calcium salts, proteins and heat.
Disodium dihydrogen pyrophosphate dispersant is used in much the same manner as polyphosphate dispersants and is subject to the same temperature limitations.
Due to its acidic nature, Disodium dihydrogen pyrophosphate is especially effective for treating cement contamination.

Disodium dihydrogen pyrophosphate dispersant is efficient for bentonite muds and is often used in conjunction with a tannin or quebracho compound.
Disodium dihydrogen pyrophosphate dispersant can also be used to treat calcium contamination, especially contamination resulting from cement.

Because of Disodium dihydrogen pyrophosphate's acidic nature, Disodium dihydrogen pyrophosphate dispersant is not normally used in muds where the pH exceeds 9.5.
Disodium dihydrogen pyrophosphate is one of the two acid components used in commercial baking powders.

Disodium dihydrogen pyrophosphate gives baking powder the time and temperature element contributing to the "Double Acting" power.
Regular Disodium dihydrogen pyrophosphate is used in cakes, sponges and refrigerated dough where a slower reactivity is desired.

Usage 1g of sodium bicarbonate to 1.38g Disodium dihydrogen pyrophosphate or as recipe indicates
Disodium dihydrogen pyrophosphate (SAPP), or Disodium pyrophosphate, Disodium dihydrogen pyrophosphate's food grade is commonly used with sodium bicarbonate as a leavening agent in bakery products.

Also, Disodium dihydrogen pyrophosphate maintains the color in processed potatoes and also prevents struvite crystal in canned seafood.
The European food additive number for Disodium dihydrogen pyrophosphate is E450(i), Disodium dihydrogen pyrophosphate.
1. Bakery
2. Canned Sea Food
3. Potato Products

Recommended use in following applications: as a constituent of baking powder, as a constituent of blanching solutions for preventing after-cooking darkening of potatoes, as a constituent of phosphate mized in meat processing, as a constituent of cheese emulsifying salts, as a general buffer and acidifying agent in foodstuffs, as a dispersant in oil well drilling muds, in leather treatment to remove iron stains, in the stabilization of hydrogen peroxide solutions, as a cleaning agent, in conjunction with sulphamic acidn in certain dairy applications, as seafood preservative.

To use: as leavening agent
Applications include food &|beverage (popular leavening agent found in baking powder, used in very sweet cakes which mask the off-tast, canned seafood, Disodium dihydrogen pyrophosphate is used to maintain color and reduce purge, frozen hash browns and other potato products, where Disodium dihydrogen pyrophosphate is used to keep the color of the potatoes from darkening)|agriculture (pet food used in cat foods as a palatability additive, removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter and |industrial (petroleum production, Disodium dihydrogen pyrophosphate can be used as a dispersant in oil well drilling muds, leather treatment to remove iron stains on hides, dairy applications for cleaning, remove soapstone).

Disodium dihydrogen pyrophosphate is used as a buffering and chelating agent, with many applications in the food industry.
Disodium dihydrogen pyrophosphate is one of the popular food additives and ingredients in most countries.

Disodium dihydrogen pyrophosphate used as buffering agent, leavening agent, sequestrant agent.
Disodium dihydrogen pyrophosphate can be used in canned food, ham, meat,baking powder and so on.

Disodium dihydrogen pyrophosphate is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.
Disodium dihydrogen pyrophosphate is used as a leavening agent, reducing zymosis time and can also be used as a water retention agent, and a quality improver for meat and sea food processing.
Disodium dihydrogen pyrophosphate is used strengthen the feed nutrition .

Disodium dihydrogen pyrophosphate, often abbreviated as SAPP is an edible phosphoric salt available as a white crystalline powder in the market.
In food and beverage industry, Disodium dihydrogen pyrophosphate is mostly used as a leavening agent in self-rising and baked goods and as a quality improver for meat and fish processing.

Besides food and beverage, Disodium dihydrogen pyrophosphate is also used in leather industry for leather processing and petroleum industry in the drilling of oil wells as dispersants.
Hence, the manufacturers are offering Disodium dihydrogen pyrophosphate in food grade or chemical so that their product can be utilized in all the above mentioned end-use industries and applications.

Consumers of Disodium dihydrogen pyrophosphate such as bakery producers are preferring the use of Disodium dihydrogen pyrophosphate as Disodium dihydrogen pyrophosphate can offer variable rates of reaction and leavening by gas production based on its granulation.
They are using Disodium dihydrogen pyrophosphate alone or in combination with other leavening agents depending on the requirement of product.

Disodium dihydrogen pyrophosphate, or SAPP, is used in the food industry.
More specially, Disodium dihydrogen pyrophosphate is used for certain types of baking powder and baking creams in addition to working as a leavening agent for prepared cake and doughnut mixes.
Disodium dihydrogen pyrophosphate maintains the natural white color of cooked potatoes.

Disodium dihydrogen pyrophosphate is used as chelating agent or buffering agent in many Food & Industrial applications.
Disodium dihydrogen pyrophosphate is used to remove Iron stains during processing of leather.
Disodium dihydrogen pyrophosphate is used as a dispersant in oil well drilling application.

Disodium dihydrogen pyrophosphate is a leavening agent, preservative, sequestrant, and buffer which is mildly acidic with a ph of 4.1.
Disodium dihydrogen pyrophosphate is moderately soluble in water, with a solubility of 15 g in 100 ml at 25°c.

Disodium dihydrogen pyrophosphate is used in doughnuts and biscuits for its variable gas release rate during the mixing, bench action, and baking process.
Disodium dihydrogen pyrophosphate is used in baking powder as a leavening agent.

Disodium dihydrogen pyrophosphate is used in canned fish products to reduce the level of undesired struvite crystals (magnesium ammonium phosphate hexahydrate) by complexing the magnesium.
Disodium dihydrogen pyrophosphate is used to sequester metals in processed potatoes.

Disodium dihydrogen pyrophosphate is currently used by the sausage industry to accelerate development of cured meat color.
The cured color accelerator was examined, through sensory evaluation and instrumental measurements, for its effects on the texture of frankfurters.

Disodium dihydrogen pyrophosphate is anhydrous form, pyrophosphate salt used in buffers.
Disodium dihydrogen pyrophosphate is used as a deflocculant (thinner) in freshwater mud systems.

Disodium dihydrogen pyrophosphate is often used to break up mud rings when water drilling and is also used to thin out cement before cementing casing.
Disodium dihydrogen pyrophosphate is used as leavening agent in baking powders, combining with sodium bicarbonate to release carbon dioxide.

Disodium dihydrogen pyrophosphate speeds the conversion of sodium nitrite to nitrite in cured meats and can improve water-holding capacity.
Disodium dihydrogen pyrophosphate is also found in potato products, where Disodium dihydrogen pyrophosphate prevents darkening.

Disodium dihydrogen pyrophosphate can be also be used in leather treatment; In some dairy applications for cleaning purposes and in petroleum production; etc.
Disodium dihydrogen pyrophosphate is used contaminated drilling mud can result in fluid loss, thickening time, and viscosity.

Disodium dihydrogen pyrophosphate is used to disperse and displace drilling muds to avoid mud being affected by cement contamination.
Disodium dihydrogen pyrophosphate is used solids carrying fluid or drilling mud must be removed from the perforation channels and the rock face to allow a good cement bond and complete fill-up of the voids.

Incorporating Disodium dihydrogen pyrophosphate into the spacer will help remove residual muds and provide a cleaner surface to which the cement can bond.
Disodium dihydrogen pyrophosphate can be used to remove iron stains on hides during processing.

Disodium dihydrogen pyrophosphate can stabilize hydrogen peroxide solutions against reduction.
Disodium dihydrogen pyrophosphate can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.

When added to scalding water, Disodium dihydrogen pyrophosphate facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.
In petroleum production, Disodium dihydrogen pyrophosphate can be used as a dispersant in oil well drilling muds.

Disodium dihydrogen pyrophosphate is used in cat foods as a palatability additive.
Disodium dihydrogen pyrophosphate is used as a tartar control agent in toothpastes.

Disodium dihydrogen pyrophosphate can be used to remove iron stains on hides during processing.
Disodium dihydrogen pyrophosphate can stabilize hydrogen peroxide solutions against reduction.

Disodium dihydrogen pyrophosphate can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.
when added to scalding water, Disodium dihydrogen pyrophosphate facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.

In petroleum production, Disodium dihydrogen pyrophosphate can be used as a dispersant in oil well drilling muds.
Disodium dihydrogen pyrophosphate is used in cat foods as a palatability additive.

Disodium dihydrogen pyrophosphate is used as a tartar control agent in toothpastes
Disodium dihydrogen pyrophosphate dispersant is used in much the same manner as polyphosphate dispersants and is subject to the same temperature limitations.

Due to its acidic nature, Disodium dihydrogen pyrophosphate is especially effective for treating cement contamination.
Disodium dihydrogen pyrophosphate dispersant is efficient for bentonite muds and is often used in conjunction with a tannin or quebracho compound.

Disodium dihydrogen pyrophosphate dispersant can also be used to treat calcium contamination, especially contamination resulting from cement.
Because of its acidic nature, SAPP dispersant is not normally used in muds where the pH exceeds 9.5.

Disodium dihydrogen pyrophosphate food grade is used as an acid component in baking powder; as a chelating agent or combines with other polyphosphates to sequester magnesium and iron ions, e.g. chelate iron during the processing of potatoes to prevent a dark discoloration.
Disodium dihydrogen pyrophosphate can be used as a leavening chemical for bread to help Disodium dihydrogen pyrophosphate rise.

Disodium dihydrogen pyrophosphate's used in sausage to enhance flavor and color.
In french fries, the chemical reduces levels of a carcinogen called acrylamide, according to an article from the Center for Science in the Public Interest.

Disodium dihydrogen pyrophosphate also prevents discoloration in potatoes and sugar syrups.
In canned tuna, Disodium dihydrogen pyrophosphate prevents harmless struvite crystals from forming.

Disodium dihydrogen pyrophosphate is used together with baking powder as a leavening agent to release carbon dioxide.
Disodium dihydrogen pyrophosphate is ideal for refrigerated doughs, cakes, muffins and pancake mixes where a slow reaction rate is desired.

Disodium dihydrogen pyrophosphate is often used with fast-acting leavenings such as monocalcium phosphate in double-acting baking powder or sometimes added with another slow action leavening acid, GDL.
Disodium dihydrogen pyrophosphate can be used to replace sulfur dioxide, sulfites and bisulfites to maintain the appearance and texture of cooked potato products.

The application of Disodium dihydrogen pyrophosphate reduces the dark color from after-cooking darkening in cooked and processed potato products, such as in oil-blanched french fries and potato salad.
Disodium dihydrogen pyrophosphate is Baking powder, used in baking and to control the fermenting speed, to increase the producing strength.

Disodium dihydrogen pyrophosphate is used in instant noodles to reduce time after subjecting to water.
Disodium dihydrogen pyrophosphate is also used in biscuits and cakes, to reduce fermenting time, to decrease the destroying, to maintain the clear gaps, finally to extend products storage.

Disodium dihydrogen pyrophosphate is speedly fermentation, water retaining agent and quality improver, used in bread, biscuits, meat, aquatic products and so on.
As quality improver, Disodium dihydrogen pyrophosphate enhances complexation,PH value and Ionic strength.

According to rules, Disodium dihydrogen pyrophosphates max adding quantity is 3.0g/KG in biscuits and 1.0-3.0g/KG in bread.
Disodium dihydrogen pyrophosphate is used in sausages to enhance flavor and color.
Disodium dihydrogen pyrophosphate is used in biscuits and cakes, Disodium dihydrogen pyrophosphate can shorten the fermentation time, reduce Disodium dihydrogen pyrophosphate breakage rate, loosen the gaps neatly, and prolong the storage period.

Disodium dihydrogen pyrophosphate is used as a quality improver for bakery foods such as bread, biscuits, meat and aquatic products, etc.
Disodium dihydrogen pyrophosphate can improve the complex metal ions, PH value and ionic strength of foods, thereby improving the adhesion and water holding capacity of foods. In French Fries, Disodium dihydrogen pyrophosphate SAPP can reduce levels of a carcinogen called acrylamide.

Disodium dihydrogen pyrophosphate can also prevent discoloration of potatoes and syrup.
In canned tuna, Disodium dihydrogen pyrophosphate can prevent the formation of harmless struvite crystals.
In canned seafood, Disodium dihydrogen pyrophosphate can retain color during cooking and reduce cleaning.

In cured meats, Disodium dihydrogen pyrophosphate accelerates the conversion of sodium nitrite to nitrite by forming a nitrous acid intermediate and can improve water retention.
Disodium dihydrogen pyrophosphate is used in frozen hash browns and other potato products to prevent potatoes from darkening.
Disodium dihydrogen pyrophosphate may leave a slightly bitter aftertaste in some products, but adding calcium ions, sugar, or flavoring can mask the taste.

In leather processing, Disodium dihydrogen pyrophosphate can be used to remove iron stains from raw hides during processing.
Disodium dihydrogen pyrophosphate can stabilize the hydrogen peroxide solution against reduction.
In certain dairy applications, Disodium dihydrogen pyrophosphate can be used with sulfamic acid for cleaning, especially soapstone removal.

In oil production, Disodium dihydrogen pyrophosphate can be used as a dispersant for oil well drilling mud.
Disodium dihydrogen pyrophosphate is used as a tartar control agent in toothpaste.
Disodium dihydrogen pyrophosphate is commonly used as a leavening agent in baked goods, such as cakes, muffins, pancakes, waffles, and biscuits.

Disodium dihydrogen pyrophosphate works by releasing carbon dioxide gas when Disodium dihydrogen pyrophosphate reacts with alkalis like baking soda (sodium bicarbonate) in the presence of moisture and heat.
This gas production causes the dough or batter to rise, resulting in the characteristic light and airy texture of these products.
Disodium dihydrogen pyrophosphate is an essential component of double-acting baking powder, a leavening agent used in a wide range of baked goods.

Double-acting baking powder releases gas in two stages: once when mixed with wet ingredients and again when exposed to the heat of the oven.
This two-stage action provides better control over the leavening process and helps achieve consistent results in baking.
Disodium dihydrogen pyrophosphate acts as a pH buffer in various food products.

Disodium dihydrogen pyrophosphate helps control and stabilize the pH (acidity or alkalinity) of food items, preventing undesirable changes in flavor, color, and texture.
Disodium dihydrogen pyrophosphate is particularly useful in processed foods to maintain the desired pH level.

Disodium dihydrogen pyrophosphate serves as an emulsifying agent.
Disodium dihydrogen pyrophosphate helps blend ingredients that would not naturally mix, such as oil and water.

This property is valuable in the production of salad dressings, sauces, and some dairy products to create stable and uniform mixtures.
Disodium dihydrogen pyrophosphate is used in the meat industry as a pH regulator and moisture retention agent in various processed meat products.

Disodium dihydrogen pyrophosphate helps improve the texture and quality of these products.
Disodium dihydrogen pyrophosphate can be found in certain dairy products, especially processed cheeses, to enhance their melting and textural characteristics.
Disodium dihydrogen pyrophosphate assists in achieving a smooth and creamy texture in cheese-based products.

In potato-based products like French fries and hash browns, Disodium dihydrogen pyrophosphate is employed to prevent discoloration and maintain the appealing color of the potatoes during processing and frying.
Disodium dihydrogen pyrophosphate is used in canned seafood products to help maintain product quality and texture, particularly in products like canned tuna.
Disodium dihydrogen pyrophosphate may be used in various other food items, such as canned soups, gravies, and sauces, where Disodium dihydrogen pyrophosphate contributes to texture and stability.

Benefits of Disodium dihydrogen pyrophosphate:
Controlled leavening acid
Prevents oxidation/colour change
Humectant
Buffering agent
Stabiliser
Acidulant

Functions of Disodium dihydrogen pyrophosphate:
Leavening acids provide air and volume to the baked good structure, but also affect the characteristics of the dough.
Besides reacting with baking soda to produce the gas carbon dioxide, these acids form ionic bonds with the starches and proteins in the dough.

Disodium dihydrogen pyrophosphate dissolves readily to form the anion pyrophosphate which interacts with the proteins in a baked good system to provide a moist texture.
Also, Disodium dihydrogen pyrophosphate provides a buffer system for the dough in the pH range 7.3-7.5, which influences the color of the baked product.

Advantages of Disodium dihydrogen pyrophosphate:
Widely available and economical thinner effective for treatment of cement contamination
Concentrated chemical that is effective at low treatment levels
Can be used with most water-base mud types

Preparation of Disodium dihydrogen pyrophosphate:
Disodium dihydrogen pyrophosphate is produced from sodium dihydrogenmonophosphate by heating at 200-250℃:
Na2CO3+2H3PO4→2NaH2PO4+H2O+CO2↑
2NaH2PO4→Na2H2P2O7+H2O

Disodium dihydrogen pyrophosphate is a condensed phosphate, commonly synthesized by the neutralization of phosphoric acid with sodium hydroxide or sodium carbonate at the ratio of 1:1 to produce monosodium phosphate (NaH2PO4), and then heated approximately 250°C to remove the water.
2 NaH2PO4 → Na2H2P2O7 + H2O

Production of Disodium dihydrogen pyrophosphate:

Commercial Production:
Disodium dihydrogen pyrophosphate is manufactured by partially neutralizing food grade phosphoric acid with sodium hydroxide or sodium carbonate to form monosodium phosphate.
Dehydration of monosodium phosphate at 250°C will form SAPP.
Currently, there is no known natural method for the production of Disodium dihydrogen pyrophosphate.

Origin of Disodium dihydrogen pyrophosphate:
In the eighteenth century and earlier, bakers relied upon yeast to leaven all baked goods.
However, using yeast for leavening baked goods was tedious and bakers began to explore the use of chemical leavening systems.
In 1846, baking soda was discovered as a leavening agent and that led to further discoveries of acids to react with baking soda, such as SAPP.

Commercially, Disodium dihydrogen pyrophosphate was introduced into baking powder blends towards the end of the nineteenth century.
Disodium dihydrogen pyrophosphate is a preferred leavening acid because Disodium dihydrogen pyrophosphate is less expensive and stronger than other leavening acids introduced previously.

Safety of Disodium dihydrogen pyrophosphate:
As with many powdered food ingredients, inhaling fine Disodium dihydrogen pyrophosphate powder can lead to respiratory irritation.
Inhaling the dust should be avoided.
Similarly, direct eye contact with the powder may cause irritation, and Disodium dihydrogen pyrophosphate is advisable to take precautions when handling the dry powder.

Disodium dihydrogen pyrophosphate itself is not typically considered a skin irritant, prolonged or repeated skin contact with the powder may lead to dryness or minor irritation for some individuals.
Disodium dihydrogen pyrophosphate is recommended to minimize skin contact and use protective gloves when handling SAPP in its dry form.

Disodium dihydrogen pyrophosphate is intended for use in food and is considered safe for consumption when used within established limits.
However, ingestion of the undiluted dry powder is not recommended, as Disodium dihydrogen pyrophosphate may cause discomfort and digestive upset.

As with any food additive, Disodium dihydrogen pyrophosphate should be used in accordance with recommended concentrations.
To ensure the safe use of Disodium dihydrogen pyrophosphate, Disodium dihydrogen pyrophosphate is crucial to adhere to food safety regulations and guidelines established by local and international authorities, such as the U.S. Food and Drug Administration (FDA) in the United States and similar agencies in other regions.

Disodium dihydrogen pyrophosphate is considered safe for consumption when used in accordance with established regulations and guidelines.
Disodium dihydrogen pyrophosphate is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA).

Handling and Storage of Disodium dihydrogen pyrophosphate:

Precautions for safe handling:

Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.

Stability and Reactivity of Disodium dihydrogen pyrophosphate:

Reactivity:
No data available

Chemical stability:
Stable under recommended storage conditions.

Possibility of hazardous reactions:
No data available

Conditions to avoid:
No data available

First Aid Measures of Disodium dihydrogen pyrophosphate:

General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.

If inhaled:
If breathed in, move person into fresh air.
Consult a physician.

In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed:
Rinse mouth with water.
Consult a physician.

Indication of any immediate medical attention and special treatment needed:
No data available

Accidental Release Measures of Disodium dihydrogen pyrophosphate:

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.

Fire Fighting Measures of Disodium dihydrogen pyrophosphate:

Extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Further information:
No data available

Exposure Controls/personal Protection of Disodium dihydrogen pyrophosphate:

Personal protective equipment:

Eye/face protection:
Use safety glasses with side-shields.

Skin protection:
Handle with gloves.
Wash and dry hands.

Body Protection:
Use Impervious clothing.

Control of environmental exposure:
Do not let product enter drains.

Identifiers of Disodium dihydrogen pyrophosphate:
CAS Registry Number: 7758-16-9
Additional Names: Disodium dihydrogen pyrophosphate
Molecular Formula: H2Na2O7P2
Molecular Weight: 221.94
Percent Composition: H 0.91%, Na 20.72%, O 50.46%, P 27.91%
Line Formula: Na2H2P2O7
Literature References: Prepn: Bell, Inorg. Synth. 3, 98 (1950).
Properties: White, fused masses or powder. Dec at 220°. d (hexahydrate) 1.86. Sol in water, the soln having an acid reaction.
Density: d (hexahydrate) 1.86
Use: Chiefly in baking powders.

Properties of Disodium dihydrogen pyrophosphate:
Melting point: decomposes 220℃ [MER06]
Density (hexahydrate): 1.86
vapor pressure: 0Pa at 20℃
storage temp.: -70°C
solubility: H2O: 0.1 M at 20 °C, clear, colorless
form: white powder
color: White to Off-White
PH: 3.5-4.5 (20℃, 0.1M in H2O, freshly prepared)
Water Solubility: Fully miscible in water. Insoluble in alcohol and ammonia.
λmax: λ: 260 nm Amax: 0.11
λ: 280 nm Amax: 0.09
Merck: 13,8643
Stability: Stable.
InChI: InChI=1S/Na.H4O7P2.H/c;1-8(2,3)7-9(4,5)6;/h;(H2,1,2,3)(H2,4,5,6);
InChIKey: IQTFITJCETVNCI-UHFFFAOYSA-N
SMILES: O(P(O)(O)=O)P(O)(O)=O.[NaH]
LogP: -3.420 (est)

Appearance Form: powder
Color: white
pH: No data available
Melting point/freezing point: > 450 °C

Relative density: 2,63 at 22,5 °C
Water solubility: 170 g/l at 20 °C

Chemical formula: Na2H2P2O7
Molar mass: 221.94 g/mol
Appearance: White odorless powder

Density: 2.31 g/cm3
Melting point: >600 °C
Solubility in water: 11.9 g/100 mL (20 °C)
Refractive index (nD): 1.4645 (hexahydrate)
Assay: ≥ 95.0 %
Moisture (at 110oC): ≤ 0.50 %
pH (1 % Solution): 4.0 – 4.6
Water Insoluble Matter: ≤ 0.1 %
Phosphate (P2O5): 63.0 – 64.5 %

Rate of CO2 Release (at 2 mins): 13.0 – 17.0 %
Neutralising Value: ≥ 72.0 %
Fluoride (As F): ≤ 10.0 ppm
Arsenic (As As): ≤ 3.0 ppm
Lead (As Pb): ≤ 2.0 ppm
Cadmium (As Cd): ≤ 1.0 ppm
Heavy Metals (As Pb): ≤ 10.0 ppm
Mercury (As Hg): ≤ 1.0 ppm

IUPAC Name: Di-sodium di-hydrogen di-phosphate
Molecular Formula: Na2H2P2O7
Molecular Weight: 222.00
Appearance: White fine Powder
PH Range (1% w/v): 3.5 – 4.5
Pyro % (minimum): 98.00
P2O5 content % (minimum): 62.00
‘Na’ Content % (minimum): 20.00
Iron as ‘Fe’ content %: 0.02
Chloride as ‘Cl’ content %: 0.2
Sulfate as ‘SO4’ content %: 0.03

Specification of Disodium dihydrogen pyrophosphate:
Cyclic Phosphates: ≤ 2%
Arsenic: ≤ 3 ppm
Lead: ≤ 2 ppm
Fluoride: ≤ 10 ppm
Loss on drying: ≤ 0.5%
Assay: ≥ 95%
pH value: 3.8 - 4.2

Releated Compounds of Disodium dihydrogen pyrophosphate:
Tetrasodium pyrophosphate

Other anions:
Disodium phosphate
Pentasodium triphosphate
Sodium hexametaphosphate

Other cations:
Calcium pyrophosphate
Dipotassium pyrophosphate
DISOPYRAMIDE
Disopyramide is an organoammonium phosphate.
Disopyramide belongs to a group of medicines called anti-arrhythmic agents used to treat irregular heartbeats.
Disopyramide is available in both oral and intravenous forms and has a low degree of toxicity.

CAS Number: 3737-09-5
EC Number: 244-756-1
Molecular Formula: C21H29N3O
Molar mass: 339.483 g·mol−1

Synonyms: Disopyramide PHOSPHATE, 22059-60-5, Norpace, Disopyramide PHOSPHATE SALT, Rythmodan, Norpace Cr, SC 7031 phosphate, Dirythmin sa, Diso-duriles, DisopyramidePhosphate, EINECS 244-756-1, SC 7031 (phosphate), NSC-756744, SC-13957, SC-7031 PHOSPHATE, CHEBI:4658, N6BOM1935W, 22059-60-5 (phosphate), SC 13957, Norpace (TN), 2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium phosphate, Disopyramid phosphate, 4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate, 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide;phosphoric acid, alpha-(2-Diisopropylaminoethyl)-alpha-phenyl-2-pyridineacetamide phosphate, (+-)-alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1), 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate, 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate (1:1), 2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl-, phosphate, alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1), 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, (+-)-, phosphate (1:1), SR-01000003039, Disopyramide (phosphate), UNII-N6BOM1935W, SCHEMBL41810, MLS000028431, SPECTRUM1500261, C21H29N3O.H3O4P, CHEMBL1201020, HMS501I11, DTXSID30944685, Disopyramide phosphate (JAN/USP), HMS1920I14, HMS2094K15, HMS2234B16, HMS3259J21, HMS3261C04, HMS3369L05, HMS3652M20, HMS3885J07, Pharmakon1600-01500261, Disopyramide PHOSPHATE [MI], XAA05960, Disopyramide PHOSPHATE [JAN], Tox21_500411, CCG-40209, Disopyramide PHOSPHATE [USAN], HY-12533A, NSC756744, Disopyramide PHOSPHATE [VANDF], AKOS040744844, Disopyramide PHOSPHATE [MART.], Disopyramide PHOSPHATE [USP-RS], Disopyramide PHOSPHATE [WHO-DD], LP00411, NC00683, NSC 756744, Disopyramide phosphate [USAN:BAN:JAN], NCGC00093836-01, NCGC00093836-02, NCGC00093836-03, NCGC00093836-04, NCGC00261096-01, SMR000058438, Disopyramide PHOSPHATE [ORANGE BOOK], LS-130131, Disopyramide PHOSPHATE [EP MONOGRAPH], Disopyramide phosphate [USAN:USP:BAN:JAN], EU-0100411, FT-0630479, S4143, SW196836-3, SW196836-4, Disopyramide PHOSPHATE [USP MONOGRAPH], C07740, D 6035, D00637, SR-01000003039-2, SR-01000003039-6, Q27106430, 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide, (R)-4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate, 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide,phosphoric acid, 4-DIISOPROPYLAMINO-2-PHENYL-2-(2-PYRIDYL)BUTYRAMIDE PHOSPHATE, Disopyramide phosphate, European Pharmacopoeia (EP) Reference Standard, Disopyramide phosphate, United States Pharmacopeia (USP) Reference Standard, (+/-)-.ALPHA.-(2-(DIISOPROPYLAMINO)ETHYL)-.ALPHA.-PHENYL-2-PYRIDINEACETAMIDE PHOSPHATE (1:1), 2-PYRIDINEACETAMIDE, .ALPHA.-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-.ALPHA.-PHENYL-, (+/-)-, PHOSPHATE (1:1), 223-110-2 [EINECS], 2-pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-phenyl-, 2-Pyridineacetamide, α-(2-(bis(1-methylethyl)amino)ethyl)-α-phenyl-, 2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl- [ACD/Index Name], 3737-09-5 [RN], 4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamid [German] [ACD/IUPAC Name], 4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamide [ACD/IUPAC Name], 4-(Diisopropylamino)-2-phényl-2-(2-pyridinyl)butanamide [French] [ACD/IUPAC Name], 4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramide, 4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide, 4-(dipropan-2-ylamino)-2-phenyl-2-(pyridin-2-yl)butanamide, a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide, a-[2-[Bis(1-methylethyl)amino]ethyl]a-phenyl-2-pyridineacetamide, disopiramida [Spanish] [INN], Disopyramide [French] [INN], Disopyramide [BAN] [INN] [JAN] [JP15] [USAN] [Wiki], Disopyramide, (R)-, Disopyramide, (S)-, disopyramidum [Latin] [INN], Isorythm, Lispine, MFCD00057366 [MDL number], Norpace [Trade name], Rythmodan [Trade name], α-[2-(DIISOPROPYLAMINO)ETHYL]-α-PHENYL-2-PYRIDINEACETAMIDE, α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide, дизопирамид [Russian] [INN], ديسوبيراميد [Arabic] [INN], 丙吡胺 [Chinese] [INN], Disopyramide free base, NORPACE CR, Rythmodan-La, ξ-Disopyramide, [3737-09-5] [RN], 1309283-08-6 [RN], 2-Pyridineacetamide, α-(2-(diisopropylamino)ethyl)-α-phenyl-, 2-Pyridineacetamide, α-[2-(diisopropylamino)ethyl]-α-phenyl-, 2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-, 3737-09-5 (free base), 38236-46-3 [RN], 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide, 4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide, 4-[bis(methylethyl)amino]-2-phenyl-2-(2-pyridyl)butanamide, 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide, 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanimidic acid, 4-[di(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide, 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide, 492056 [Beilstein], 4-Diisopropylamino-2-phenyl-2-(2-pyridyl)-butyramide, 54687-36-4 [RN], 74464-83-8 [RN], 74464-84-9 [RN], BS-17145, DB00280, Dicorantil, Disopiramida, Disopiramida [INN-Spanish], Disopyramide-d5, Disopyramidum, Disopyramidum [INN-Latin], MFCD00069254 [MDL number], n-desalkyl Disopyramide, Norpace®, Ritmodan, Rythmodan P [Trade name], Rythmodan®, Searle 703, α-(2-(Diisopropylamino)ethyl)-α-phenyl-2-pyridineacetamide, α-(2-(Diisopropylamino)ethyl)-α-phenyl-2-pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-2-pyridineacetamide, γ-Diisopropylamino-α-phenyl-α-(2-pyridyl)butyramide, γ-Diisopropylamino-α-phenyl-α-(2-pyridyl)butyramide, дизопирамид, ديسوبيراميد, 丙吡胺

Disopyramide is an antiarrhythmic chemical used in the treatment of ventricular tachycardia.
Disopyramide is a sodium channel blocker and is classified as a Class 1a anti-arrhythmic agent.

Disopyramide has a negative inotropic effect on the ventricular myocardium and significantly reduces contractility.
Disopyramide also has an anticholinergic effect on the heart, which is responsible for many negative side effects.
Disopyramide is available in both oral and intravenous forms and has a low degree of toxicity.

Disopyramide is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only.
Disopyramide is used at industrial sites and in manufacturing.

Disopyramide is an organoammonium phosphate.

Disopyramide is a class Ia antiarrhythmic agent with cardiac depressant properties.
Disopyramide exerts Disopyramide actions by blocking both sodium and potassium channels in cardiac membrane during phase 0 of the action potential.

This slows the impulse conduction through the AV node and prolongs the duration of the action potential of normal cardiac cells in atrial and ventricular tissues.
Disopyramide prolongs the QT interval and causes a widening of the QRS complex.

Disopyramide also possesses some anticholinergic and local anaesthetic properties.
Disopyramide is used in the treatment of supraventricular tachycardia.

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine.
Disopyramide also possesses some anticholinergic and local anesthetic properties.

Disopyramide belongs to a group of medicines called anti-arrhythmic agents used to treat irregular heartbeats.
An irregular heartbeat is a condition in which your heart beats irregularly, too fast, or too slow.
Disopyramide helps slow the heart rate and prevent arrhythmias (abnormal heart rhythms).

Disopyramide sulphate contains Disopyramide, ie anti-arrhythmic agents.
Disopyramide helps bring irregular heartbeats to a normal rhythm by blocking certain electrical signals in the heart.
Irregular heartbeat treatment reduces the risk of blood clots, heart attack or stroke.

Disopyramide should be taken as prescribed by the doctor.
Your doctor may monitor EKGs and blood pressure during treatment to monitor your dose.

Some people may experience common side effects such as blurred or double vision, stomach pain, little or no urination, and low blood sugar.
Most of these side effects of Disopyramide do not require medical attention and will gradually improve over time.
However, if the side effects persist, please consult your doctor.

Please tell your doctor if you are known to be allergic to Disopyramide or any other medicines.
Disopyramide is not recommended for use in children.
Pregnant or breastfeeding women are advised to consult a doctor before taking Disopyramide.

Before taking Disopyramide, tell your doctor if you have kidney or liver disease, enlarged prostate, glaucoma (increased eye pressure) or low potassium levels in the blood (hypokalaemia).
Do not take Disopyramide if you are already taking other medicines to regulate your heartbeat.

Do not drive or operate machinery as Disopyramide may cause blurred vision, dizziness and low blood pressure.
Use Disopyramide with caution if you are elderly (over 65 years of age), have a low body weight, or have kidney or liver problems.

Disopyramide is used to treat certain irregular heartbeats).
Disopyramide is in a class of medications called antiarrhythmic drugs.
Disopyramide works by making your heart more resistant to abnormal activity.

Continuing Education Activity:
Disopyramide is a chemical used to treat heart rhythm abnormalities that can be life-threatening, such as ventricular tachycardia/fibrillation, or associated with increased morbidity and mortality, such as atrial fibrillation and hypertrophic cardiomyopathy.
This activity reviews several important aspects of this chemical, including indications, mechanism of action, applications, side effects, contraindications, monitoring, and toxicity.
This important knowledge of this chemical can improve interprofessional healthcare team outcomes.

Objectives:
Describe the mechanism of action of Disopyramide.
Describe possible side effects of Disopyramide.

Explains the importance of monitoring when using Disopyramide as an antiarrhythmic chemical.
Outline professional team strategies for improving care coordination and communication when using Disopyramide to maximize the benefits of this chemical and minimize Disopyramide side effects.

Indications:
In 1962, new antiarrhythmic drugs were needed apart from quinidine and procainamide, which were the main antiarrhythmic agents available at the time.
Disopyramide is the selected agent among more than 500 compounds synthesized for the research program of new antiarrhythmic agents.
The chemical structures of Disopyramide are similar to the synthetic muscarinic antagonist lacquer, which explains Disopyramide anticholinergic property.

Although Disopyramide is rarely used for heart rhythm abnormalities due to the availability of newer drugs that provide better efficacy and favorable side-effect profiles, Disopyramide is still the drug of choice for vagal-mediated atrial fibrillation such as sleep-induced or atrial fibrillation in athlete groups.
The effectiveness of Disopyramide in these conditions is due to Disopyramide anticholinergic activity, which abolishes the parasympathetic tone.

Disopyramide is also a third-line antiarrhythmic agent for a patient with coronary artery disease.
Also, a patient with left ventricular hypertrophy has impaired depolarization, which can induce torsade de pointes.

Therefore, antiarrhythmics that prolong the QT interval are avoided, but if sotalol or amiodarone is unsuccessful or unsuitable, Disopyramide may be an alternative.
In a patient with atrial fibrillation and hypertrophic obstructive cardiomyopathy (HOCM), Disopyramide is the agent of choice, other than amiodarone, as Disopyramide may decrease the left ventricular outflow tract (LVOT) gradient (off-label use).

Data from a multicenter study of the safety and efficacy of Disopyramide in obstructive cardiomyopathy showed that Disopyramide significantly reduced the SVOT gradient from 75+/- 33 to 40+/-32 mmHg in 78 patients (66% of study subjects) (P<0.0001). has shown. ) and raises the New York Heart Association functional class (NYHA FC) from 23+/-07 to 17+/-06 (P<0.0001).
When Disopyramide is used in combination with a non-dihydropyridine calcium channel blocker or beta blocker, they can effectively prevent recurrence of AF in HCOM patients.

Patients with ventricular premature beat (VPB) or premature ventricular complexes (PVC) may have a high symptom burden.
Disopyramide can be used in patients without structural heart disease, although Disopyramide efficacy is less than ablation.
In addition, based on a randomized, double-blind, placebo-controlled one-year follow-up study, Disopyramide (n=44) was effective in maintaining sinus rhythm after electro cardioversion for atrial fibrillation compared to placebo (n=46) and was significantly different (%) at one-month follow-up. 70 vs 39%) and continues after twelve months (54% vs 30%).

Uses of Disopyramide:
Disopyramide is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as sustained ventricular tachycardia).
Disopyramide is used to restore normal heart rhythm and maintain a regular, steady heartbeat.

Disopyramide is known as an anti-arrhythmic drug.
Disopyramide works by blocking certain electrical signals in the heart that can cause an irregular heartbeat.
Treating an irregular heartbeat can decrease the risk for blood clots, and this effect can reduce your risk of heart attack or stroke.

Usage of Disopyramide:
Disopyramide comes as a capsule and an extended-release (long-acting) capsule to take by mouth.
Disopyramide capsules may be taken every 6 or 8 hours.

The extended-release capsule is usually taken every 12 hours.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Take Disopyramide exactly as directed.
Do not take more or less of Disopyramide or take it more often than prescribed by your doctor.

Swallow the extended-release capsules; do not open, crush, or chew them.

Disopyramide helps control your condition but will not cure it.
Continue to take Disopyramide even if you feel well.
Do not stop taking Disopyramide without talking to your doctor.

Mechanism of action of Disopyramide:
Disopyramide's Class 1a activity is similar to that of quinidine in that Disopyramide targets sodium channels to inhibit conduction.
Disopyramide depresses the increase in sodium permeability of the cardiac myocyte during Phase 0 of the cardiac action potential, in turn decreasing the inward sodium current.

This results in an increased threshold for excitation and a decreased upstroke velocity.
Disopyramide prolongs the PR interval by lengthening both the QRS and P wave duration.

This effect is particularly well suited in the treatment of ventricular tachycardia as Disopyramide slows the action potential propagation through the atria to the ventricles.
Disopyramide does not act as a blocking agent for beta or alpha adrenergic receptors, but does have a significant negative inotropic effect on the ventricular myocardium.
As a result, the use of Disopyramide may reduce contractile force up to 42% at low doses and up to 100% in higher doses compared to quinidine.

Levites proposed a possible secondary mode of action for Disopyramide, against reentrant arrhythmias after an ischemic insult.
Disopyramide decreases the inhomogeneity between infarcted and normal myocardium refractory periods; in addition to lengthening the refractory period.

This decreases the chance of re-entry depolarization, because signals are more likely to encounter tissue in a refractory state which cannot be excited.
This provides a possible treatment for atrial and ventricular fibrillation, as Disopyramide restores pacemaker control of the tissue to the SA and AV nodes.

Pharmacology and Biochemistry of Disopyramide:

MeSH Pharmacological Classification:

Anti-Arrhythmia Agents:
Agents used for the treatment or prevention of cardiac arrhythmias.
They may affect the polarization-repolarization phase of the action potential, Disopyramide excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers.
Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.

Obstructive hypertrophic cardiomyopathy:
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease, occurring in 1:500 individuals in the general population.
Disopyramide is estimated that there are 600,000 individuals in the United States with hypertrophic cardiomyopathy.

The most common variant of HCM presents with left ventricular (LV) intracavitary obstruction due to systolic anterior motion of the mitral valve, and mitral-septal contact, diagnosed readily with echocardiography.
Pharmacologic treatment with negative inotropic drugs is first-line therapy.

Beta-blockers are used first, and while they improve symptoms of shortness of breath, chest pain and exercise intolerance, they do not reduce resting LV intraventricular pressure gradients and often are inadequate to control symptoms.
Many investigators and clinicians believe that Disopyramide controlled release is the most potent agent available for reducing resting pressure gradients and improving symptoms.

Disopyramide has been actively used for more than 30 years.
Disopyramide administration for obstructive HCM has a IB recommendation in the 2020 American Heart Association/American College of Cardiology Foundation guidelines for treatment of obstructive HCM.
A IB treatment recommendation indicates that a treatment is recommended, and may be useful, and beneficial.

Negative inotropes improve LV obstruction by decreasing LV ejection acceleration and hydrodynamic forces on the mitral valve.
Disopyramide's particular efficacy is due to Disopyramide potent negative inotropic effects; in head-to-head comparison, Disopyramide is more effective for gradient reduction than either beta-blocker or verapamil.

Disopyramide is most often administered with beta-blockade.
When used in patients resistant to beta-blockade, Disopyramide is effective in 60% of cases, reducing symptoms and gradient to the extent that invasive procedures such as surgical septal myectomy are not required.

Disopyramide, despite Disopyramide efficacy, has one main side effect that has limited Disopyramide use in the US, though Disopyramide has seen wider application in Canada, UK and Japan.
Vagal blockade predictably causes dry mouth, and in men with prostatism, may cause urinary retention.
Teichman et al. showed that pyridostigmine used in combination with Disopyramide substantially alleviates vagolytic side effects without compromising antiarrhythmic efficacy.

This combination has also been shown to be effective and safe in obstructive HCM in a large cohort of patients.
Some clinicians prescribe pyridostigmine sustained release (marketed in the US as Mestinon Timespan) to every patient begun on Disopyramide.
This combination increases acceptance of higher Disopyramide dosing, important since there is a dose-response correlation in obstructive HCM, higher doses yielding lower gradients.

Another concern about Disopyramide has been the hypothetical potential for inducing sudden death from Disopyramide type 1 anti-arrhythmic effects.
However, a multicenter registry and two recent cohort registries have largely reduced this concern, by showing sudden death rates lower than that observed from the disease itself.

These concerns about the drug must be viewed from the clinical perspective that Disopyramide is generally the last agent that is tried for patients before they are referred for invasive septal reduction with surgical septal myectomy (an open-heart operation) or alcohol septal ablation (a controlled heart attack).
Both of these invasive procedures have risk of morbidity and mortality.

For selected patients, a trial of oral Disopyramide is a reasonable approach before proceeding to invasive septal reduction.
Patients who respond to Disopyramide are continued on the drug.

Those who continue to have disabling symptoms or who experience side effects are promptly referred for septal reduction.
Using such a stepped strategy, investigators have reported that survival does not differ from that observed in the age-matched normal United States population.

Extracardiac effects:
Atropine like effects (anticholinergic)
Dry mouth
Constipation
Urinary retention – Disopyramide should not be given to patients with symptomatic prostatism.
Blurred vision
Glaucoma
Rash
Agranulocytosis

Additionally, Disopyramide may enhance the hypoglycaemic effect of gliclazide, insulin, and metformin.

Metabolism of Disopyramide:
Disopyramide can cause hypoglycemia, perhaps due to increased secretion of insulin, and can also potentiate the effects of conventional hypoglycemic drugs.
This effect may be due to Disopyramide chief metabolite mono-N dealkylDisopyramide, since many of the reported cases of hypoglycemia have been in patients with renal impairment, in which the metabolite accumulates.

In six subjects who were being considered for treatment with Disopyramide, serum glucose concentrations were measured at 13, 15, 17, and 19 hours after supper, with no further food, with and without the added administration of two modified-released tablets of Disopyramide 150 mg with supper and 12 hours later.
Disopyramide significantly reduced the serum glucose concentration at all measurement times by an average of 0.54 mmol/l.
The fall in serum glucose concentration was not related to the serum concentration of Disopyramide or the serum creatinine concentration; Disopyramide was greater in older patients and in underweight patients.

Hypoglycemia has also been reported in a 70-year-old woman with type 2 diabetes mellitus taking Disopyramide.

Clinical data of Disopyramide:
Trade names: Norpace
AHFS/Drugs.com: Monograph
MedlinePlus: a682408
Pregnancy category: AU: B2
Routes ofadministration: Oral, intravenous
ATC code: C01BA03 (WHO)

Legal status:
UK: POM (Prescription only)
US: ℞-only

Pharmacokinetic data of Disopyramide:
Bioavailability: High
Protein binding: 50% to 65% (concentration-dependent)
Metabolism: Hepatic (CYP3A4-mediated)
Elimination half-life: 6.7 hours (range 4 to 10 hours)
Excretion: Renal (80%)

Identifiers of Disopyramide:
IUPAC name: (RS)-4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
CAS Number: 3737-09-5
PubChem CID: 3114
IUPHAR/BPS: 7167
DrugBank: DB00280
ChemSpider: 3002
UNII: GFO928U8MQ
KEGG: D00303
ChEBI: CHEBI:4657
ChEMBL: ChEMBL517
CompTox Dashboard (EPA): DTXSID1045536
ECHA InfoCard: 100.021.010

Properties of Disopyramide:
Formula: C21H29N3O
Molar mass: 339.483 g·mol−1
Melting point: 94.5 to 95 °C (202.1 to 203.0 °F)
SMILES: O=C(N)C(c1ncccc1)(c2ccccc2)CCN(C(C)C)C(C)C
InChI: InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)
Key:UVTNFZQICZKOEM-UHFFFAOYSA-N

Molecular Weight: 437.5 g/mol
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 8
Exact Mass: 437.20795813 g/mol
Monoisotopic Mass: 437.20795813 g/mol
Topological Polar Surface Area: 137Ų
Heavy Atom Count: 30
Complexity: 459
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Names of Disopyramide:

Regulatory process names:
Disopyramide
Disopyramide

IUPAC names:
4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
Disopyramide

Other identifiers:
3737-09-5
DISOPYRAMIDE
Disopyramide is an organoammonium phosphate.
Disopyramide belongs to a group of medicines called anti-arrhythmic agents used to treat irregular heartbeats.
Disopyramide is available in both oral and intravenous forms and has a low degree of toxicity.

CAS Number: 3737-09-5
Formula: C21H29N3O
Molar mass: 339.483 g·mol−1

Disopyramide is an antiarrhythmic chemical used in the treatment of ventricular tachycardia.
Disopyramide is a sodium channel blocker and is classified as a Class 1a anti-arrhythmic agent.

Disopyramide has a negative inotropic effect on the ventricular myocardium and significantly reduces contractility.
Disopyramide also has an anticholinergic effect on the heart, which is responsible for many negative side effects.
Disopyramide is available in both oral and intravenous forms and has a low degree of toxicity.

Disopyramide is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only.
Disopyramide is used at industrial sites and in manufacturing.

Disopyramide is an organoammonium phosphate.

Disopyramide is a class Ia antiarrhythmic agent with cardiac depressant properties.
Disopyramide exerts Disopyramide actions by blocking both sodium and potassium channels in cardiac membrane during phase 0 of the action potential.

This slows the impulse conduction through the AV node and prolongs the duration of the action potential of normal cardiac cells in atrial and ventricular tissues.
Disopyramide prolongs the QT interval and causes a widening of the QRS complex.

Disopyramide also possesses some anticholinergic and local anaesthetic properties.
Disopyramide is used in the treatment of supraventricular tachycardia.

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine.
Disopyramide also possesses some anticholinergic and local anesthetic properties.

Disopyramide belongs to a group of medicines called anti-arrhythmic agents used to treat irregular heartbeats.
An irregular heartbeat is a condition in which your heart beats irregularly, too fast, or too slow.
Disopyramide helps slow the heart rate and prevent arrhythmias (abnormal heart rhythms).

Disopyramide sulphate contains Disopyramide, ie anti-arrhythmic agents.
Disopyramide helps bring irregular heartbeats to a normal rhythm by blocking certain electrical signals in the heart.
Irregular heartbeat treatment reduces the risk of blood clots, heart attack or stroke.

Disopyramide should be taken as prescribed by the doctor.
Your doctor may monitor EKGs and blood pressure during treatment to monitor your dose.

Some people may experience common side effects such as blurred or double vision, stomach pain, little or no urination, and low blood sugar.
Most of these side effects of Disopyramide do not require medical attention and will gradually improve over time.
However, if the side effects persist, please consult your doctor.

Please tell your doctor if you are known to be allergic to Disopyramide or any other medicines.
Disopyramide is not recommended for use in children.
Pregnant or breastfeeding women are advised to consult a doctor before taking Disopyramide.

Before taking Disopyramide, tell your doctor if you have kidney or liver disease, enlarged prostate, glaucoma (increased eye pressure) or low potassium levels in the blood (hypokalaemia).
Do not take Disopyramide if you are already taking other medicines to regulate your heartbeat.

Do not drive or operate machinery as Disopyramide may cause blurred vision, dizziness and low blood pressure.
Use Disopyramide with caution if you are elderly (over 65 years of age), have a low body weight, or have kidney or liver problems.

Disopyramide is used to treat certain irregular heartbeats).
Disopyramide is in a class of medications called antiarrhythmic drugs.
Disopyramide works by making your heart more resistant to abnormal activity.

Continuing Education Activity:
Disopyramide is a chemical used to treat heart rhythm abnormalities that can be life-threatening, such as ventricular tachycardia/fibrillation, or associated with increased morbidity and mortality, such as atrial fibrillation and hypertrophic cardiomyopathy.
This activity reviews several important aspects of this chemical, including indications, mechanism of action, applications, side effects, contraindications, monitoring, and toxicity.
This important knowledge of this chemical can improve interprofessional healthcare team outcomes.

Objectives:
Describe the mechanism of action of Disopyramide.
Describe possible side effects of Disopyramide.

Explains the importance of monitoring when using Disopyramide as an antiarrhythmic chemical.
Outline professional team strategies for improving care coordination and communication when using Disopyramide to maximize the benefits of this chemical and minimize Disopyramide side effects.

Indications:
In 1962, new antiarrhythmic drugs were needed apart from quinidine and procainamide, which were the main antiarrhythmic agents available at the time.
Disopyramide is the selected agent among more than 500 compounds synthesized for the research program of new antiarrhythmic agents.
The chemical structures of Disopyramide are similar to the synthetic muscarinic antagonist lacquer, which explains Disopyramide anticholinergic property.

Although Disopyramide is rarely used for heart rhythm abnormalities due to the availability of newer drugs that provide better efficacy and favorable side-effect profiles, Disopyramide is still the drug of choice for vagal-mediated atrial fibrillation such as sleep-induced or atrial fibrillation in athlete groups.
The effectiveness of Disopyramide in these conditions is due to Disopyramide anticholinergic activity, which abolishes the parasympathetic tone.

Disopyramide is also a third-line antiarrhythmic agent for a patient with coronary artery disease.
Also, a patient with left ventricular hypertrophy has impaired depolarization, which can induce torsade de pointes.

Therefore, antiarrhythmics that prolong the QT interval are avoided, but if sotalol or amiodarone is unsuccessful or unsuitable, Disopyramide may be an alternative.
In a patient with atrial fibrillation and hypertrophic obstructive cardiomyopathy (HOCM), Disopyramide is the agent of choice, other than amiodarone, as Disopyramide may decrease the left ventricular outflow tract (LVOT) gradient (off-label use).

Data from a multicenter study of the safety and efficacy of Disopyramide in obstructive cardiomyopathy showed that Disopyramide significantly reduced the SVOT gradient from 75+/- 33 to 40+/-32 mmHg in 78 patients (66% of study subjects) (P<0.0001). has shown. ) and raises the New York Heart Association functional class (NYHA FC) from 23+/-07 to 17+/-06 (P<0.0001).
When Disopyramide is used in combination with a non-dihydropyridine calcium channel blocker or beta blocker, they can effectively prevent recurrence of AF in HCOM patients.

Patients with ventricular premature beat (VPB) or premature ventricular complexes (PVC) may have a high symptom burden.
Disopyramide can be used in patients without structural heart disease, although Disopyramide efficacy is less than ablation.
In addition, based on a randomized, double-blind, placebo-controlled one-year follow-up study, Disopyramide (n=44) was effective in maintaining sinus rhythm after electro cardioversion for atrial fibrillation compared to placebo (n=46) and was significantly different (%) at one-month follow-up. 70 vs 39%) and continues after twelve months (54% vs 30%).

Uses of Disopyramide:
Disopyramide is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as sustained ventricular tachycardia).
Disopyramide is used to restore normal heart rhythm and maintain a regular, steady heartbeat.

Disopyramide is known as an anti-arrhythmic drug.
Disopyramide works by blocking certain electrical signals in the heart that can cause an irregular heartbeat.
Treating an irregular heartbeat can decrease the risk for blood clots, and this effect can reduce your risk of heart attack or stroke.

Usage of Disopyramide:
Disopyramide comes as a capsule and an extended-release (long-acting) capsule to take by mouth.
Disopyramide capsules may be taken every 6 or 8 hours.

The extended-release capsule is usually taken every 12 hours.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Take Disopyramide exactly as directed.
Do not take more or less of Disopyramide or take it more often than prescribed by your doctor.

Swallow the extended-release capsules; do not open, crush, or chew them.

Disopyramide helps control your condition but will not cure it.
Continue to take Disopyramide even if you feel well.
Do not stop taking Disopyramide without talking to your doctor.

Mechanism of action of Disopyramide:
Disopyramide's Class 1a activity is similar to that of quinidine in that Disopyramide targets sodium channels to inhibit conduction.
Disopyramide depresses the increase in sodium permeability of the cardiac myocyte during Phase 0 of the cardiac action potential, in turn decreasing the inward sodium current.

This results in an increased threshold for excitation and a decreased upstroke velocity.
Disopyramide prolongs the PR interval by lengthening both the QRS and P wave duration.

This effect is particularly well suited in the treatment of ventricular tachycardia as Disopyramide slows the action potential propagation through the atria to the ventricles.
Disopyramide does not act as a blocking agent for beta or alpha adrenergic receptors, but does have a significant negative inotropic effect on the ventricular myocardium.
As a result, the use of Disopyramide may reduce contractile force up to 42% at low doses and up to 100% in higher doses compared to quinidine.

Levites proposed a possible secondary mode of action for Disopyramide, against reentrant arrhythmias after an ischemic insult.
Disopyramide decreases the inhomogeneity between infarcted and normal myocardium refractory periods; in addition to lengthening the refractory period.

This decreases the chance of re-entry depolarization, because signals are more likely to encounter tissue in a refractory state which cannot be excited.
This provides a possible treatment for atrial and ventricular fibrillation, as Disopyramide restores pacemaker control of the tissue to the SA and AV nodes.

Pharmacology and Biochemistry of Disopyramide:

MeSH Pharmacological Classification:

Anti-Arrhythmia Agents:
Agents used for the treatment or prevention of cardiac arrhythmias.
They may affect the polarization-repolarization phase of the action potential, Disopyramide excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers.
Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.

Obstructive hypertrophic cardiomyopathy:
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease, occurring in 1:500 individuals in the general population.
Disopyramide is estimated that there are 600,000 individuals in the United States with hypertrophic cardiomyopathy.

The most common variant of HCM presents with left ventricular (LV) intracavitary obstruction due to systolic anterior motion of the mitral valve, and mitral-septal contact, diagnosed readily with echocardiography.
Pharmacologic treatment with negative inotropic drugs is first-line therapy.

Beta-blockers are used first, and while they improve symptoms of shortness of breath, chest pain and exercise intolerance, they do not reduce resting LV intraventricular pressure gradients and often are inadequate to control symptoms.
Many investigators and clinicians believe that Disopyramide controlled release is the most potent agent available for reducing resting pressure gradients and improving symptoms.

Disopyramide has been actively used for more than 30 years.
Disopyramide administration for obstructive HCM has a IB recommendation in the 2020 American Heart Association/American College of Cardiology Foundation guidelines for treatment of obstructive HCM.
A IB treatment recommendation indicates that a treatment is recommended, and may be useful, and beneficial.

Negative inotropes improve LV obstruction by decreasing LV ejection acceleration and hydrodynamic forces on the mitral valve.
Disopyramide's particular efficacy is due to Disopyramide potent negative inotropic effects; in head-to-head comparison, Disopyramide is more effective for gradient reduction than either beta-blocker or verapamil.

Disopyramide is most often administered with beta-blockade.
When used in patients resistant to beta-blockade, Disopyramide is effective in 60% of cases, reducing symptoms and gradient to the extent that invasive procedures such as surgical septal myectomy are not required.

Disopyramide, despite Disopyramide efficacy, has one main side effect that has limited Disopyramide use in the US, though Disopyramide has seen wider application in Canada, UK and Japan.
Vagal blockade predictably causes dry mouth, and in men with prostatism, may cause urinary retention.
Teichman et al. showed that pyridostigmine used in combination with Disopyramide substantially alleviates vagolytic side effects without compromising antiarrhythmic efficacy.

This combination has also been shown to be effective and safe in obstructive HCM in a large cohort of patients.
Some clinicians prescribe pyridostigmine sustained release (marketed in the US as Mestinon Timespan) to every patient begun on Disopyramide.
This combination increases acceptance of higher Disopyramide dosing, important since there is a dose-response correlation in obstructive HCM, higher doses yielding lower gradients.

Another concern about Disopyramide has been the hypothetical potential for inducing sudden death from Disopyramide type 1 anti-arrhythmic effects.
However, a multicenter registry and two recent cohort registries have largely reduced this concern, by showing sudden death rates lower than that observed from the disease itself.

These concerns about the drug must be viewed from the clinical perspective that Disopyramide is generally the last agent that is tried for patients before they are referred for invasive septal reduction with surgical septal myectomy (an open-heart operation) or alcohol septal ablation (a controlled heart attack).
Both of these invasive procedures have risk of morbidity and mortality.

For selected patients, a trial of oral Disopyramide is a reasonable approach before proceeding to invasive septal reduction.
Patients who respond to Disopyramide are continued on the drug.

Those who continue to have disabling symptoms or who experience side effects are promptly referred for septal reduction.
Using such a stepped strategy, investigators have reported that survival does not differ from that observed in the age-matched normal United States population.

Extracardiac effects:
Atropine like effects (anticholinergic)
Dry mouth
Constipation
Urinary retention – Disopyramide should not be given to patients with symptomatic prostatism.
Blurred vision
Glaucoma
Rash
Agranulocytosis

Additionally, Disopyramide may enhance the hypoglycaemic effect of gliclazide, insulin, and metformin.

Metabolism of Disopyramide:
Disopyramide can cause hypoglycemia, perhaps due to increased secretion of insulin, and can also potentiate the effects of conventional hypoglycemic drugs.
This effect may be due to Disopyramide chief metabolite mono-N dealkylDisopyramide, since many of the reported cases of hypoglycemia have been in patients with renal impairment, in which the metabolite accumulates.

In six subjects who were being considered for treatment with Disopyramide, serum glucose concentrations were measured at 13, 15, 17, and 19 hours after supper, with no further food, with and without the added administration of two modified-released tablets of Disopyramide 150 mg with supper and 12 hours later.
Disopyramide significantly reduced the serum glucose concentration at all measurement times by an average of 0.54 mmol/l.
The fall in serum glucose concentration was not related to the serum concentration of Disopyramide or the serum creatinine concentration; Disopyramide was greater in older patients and in underweight patients.

Hypoglycemia has also been reported in a 70-year-old woman with type 2 diabetes mellitus taking Disopyramide.

Clinical data of Disopyramide:
Trade names: Norpace
AHFS/Drugs.com: Monograph
MedlinePlus: a682408
Pregnancy category: AU: B2
Routes ofadministration: Oral, intravenous
ATC code: C01BA03 (WHO)

Legal status:
UK: POM (Prescription only)
US: ℞-only

Pharmacokinetic data of Disopyramide:
Bioavailability: High
Protein binding: 50% to 65% (concentration-dependent)
Metabolism: Hepatic (CYP3A4-mediated)
Elimination half-life: 6.7 hours (range 4 to 10 hours)
Excretion: Renal (80%)

Identifiers of Disopyramide:
IUPAC name: (RS)-4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
CAS Number: 3737-09-5
PubChem CID: 3114
IUPHAR/BPS: 7167
DrugBank: DB00280
ChemSpider: 3002
UNII: GFO928U8MQ
KEGG: D00303
ChEBI: CHEBI:4657
ChEMBL: ChEMBL517
CompTox Dashboard (EPA): DTXSID1045536
ECHA InfoCard: 100.021.010

Properties of Disopyramide:
Formula: C21H29N3O
Molar mass: 339.483 g·mol−1
Melting point: 94.5 to 95 °C (202.1 to 203.0 °F)
SMILES: O=C(N)C(c1ncccc1)(c2ccccc2)CCN(C(C)C)C(C)C
InChI: InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)
Key:UVTNFZQICZKOEM-UHFFFAOYSA-N

Molecular Weight: 437.5 g/mol
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 8
Exact Mass: 437.20795813 g/mol
Monoisotopic Mass: 437.20795813 g/mol
Topological Polar Surface Area: 137Ų
Heavy Atom Count: 30
Complexity: 459
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Names of Disopyramide:

Regulatory process names:
Disopyramide
Disopyramide

IUPAC names:
4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
Disopyramide

Other identifiers:
3737-09-5

Synonyms of Disopyramide:
Disopyramide PHOSPHATE
22059-60-5
Norpace
Disopyramide PHOSPHATE SALT
Rythmodan
Norpace Cr
SC 7031 phosphate
Dirythmin sa
Diso-duriles
DisopyramidePhosphate
EINECS 244-756-1
SC 7031 (phosphate)
NSC-756744
SC-13957
SC-7031 PHOSPHATE
CHEBI:4658
N6BOM1935W
22059-60-5 (phosphate)
SC 13957
Norpace (TN)
2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium phosphate
Disopyramid phosphate
4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide;phosphoric acid
alpha-(2-Diisopropylaminoethyl)-alpha-phenyl-2-pyridineacetamide phosphate
(+-)-alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1)
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate (1:1)
2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl-, phosphate
alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1)
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, (+-)-, phosphate (1:1)
SR-01000003039
Disopyramide (phosphate)
UNII-N6BOM1935W
SCHEMBL41810
MLS000028431
SPECTRUM1500261
C21H29N3O.H3O4P
CHEMBL1201020
HMS501I11
DTXSID30944685
Disopyramide phosphate (JAN/USP)
HMS1920I14
HMS2094K15
HMS2234B16
HMS3259J21
HMS3261C04
HMS3369L05
HMS3652M20
HMS3885J07
Pharmakon1600-01500261
Disopyramide PHOSPHATE [MI]
XAA05960
Disopyramide PHOSPHATE [JAN]
Tox21_500411
CCG-40209
Disopyramide PHOSPHATE [USAN]
HY-12533A
NSC756744
Disopyramide PHOSPHATE [VANDF]
AKOS040744844
Disopyramide PHOSPHATE [MART.]
Disopyramide PHOSPHATE [USP-RS]
Disopyramide PHOSPHATE [WHO-DD]
LP00411
NC00683
NSC 756744
Disopyramide phosphate [USAN:BAN:JAN]
NCGC00093836-01
NCGC00093836-02
NCGC00093836-03
NCGC00093836-04
NCGC00261096-01
SMR000058438
Disopyramide PHOSPHATE [ORANGE BOOK]
LS-130131
Disopyramide PHOSPHATE [EP MONOGRAPH]
Disopyramide phosphate [USAN:USP:BAN:JAN]
EU-0100411
FT-0630479
S4143
SW196836-3
SW196836-4
Disopyramide PHOSPHATE [USP MONOGRAPH]
C07740
D 6035
D00637
SR-01000003039-2
SR-01000003039-6
Q27106430
4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide
(R)-4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide,phosphoric acid
4-DIISOPROPYLAMINO-2-PHENYL-2-(2-PYRIDYL)BUTYRAMIDE PHOSPHATE
Disopyramide phosphate, European Pharmacopoeia (EP) Reference Standard
Disopyramide phosphate, United States Pharmacopeia (USP) Reference Standard
(+/-)-.ALPHA.-(2-(DIISOPROPYLAMINO)ETHYL)-.ALPHA.-PHENYL-2-PYRIDINEACETAMIDE PHOSPHATE (1:1)
2-PYRIDINEACETAMIDE, .ALPHA.-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-.ALPHA.-PHENYL-, (+/-)-, PHOSPHATE (1:1)
223-110-2 [EINECS]
2-pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-phenyl-
2-Pyridineacetamide, α-(2-(bis(1-methylethyl)amino)ethyl)-α-phenyl-
2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl- [ACD/Index Name]
3737-09-5 [RN]
4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamid [German] [ACD/IUPAC Name]
4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamide [ACD/IUPAC Name]
4-(Diisopropylamino)-2-phényl-2-(2-pyridinyl)butanamide [French] [ACD/IUPAC Name]
4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramide
4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
4-(dipropan-2-ylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide
a-[2-[Bis(1-methylethyl)amino]ethyl]a-phenyl-2-pyridineacetamide
disopiramida [Spanish] [INN]
Disopyramide [French] [INN]
Disopyramide [BAN] [INN] [JAN] [JP15] [USAN] [Wiki]
Disopyramide, (R)-
Disopyramide, (S)-
disopyramidum [Latin] [INN]
Isorythm
Lispine
MFCD00057366 [MDL number]
Norpace [Trade name]
Rythmodan [Trade name]
α-[2-(DIISOPROPYLAMINO)ETHYL]-α-PHENYL-2-PYRIDINEACETAMIDE
α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide
дизопирамид [Russian] [INN]
ديسوبيراميد [Arabic] [INN]
丙吡胺 [Chinese] [INN]
Disopyramide free base
NORPACE CR
Rythmodan-La
ξ-Disopyramide
[3737-09-5] [RN]
1309283-08-6 [RN]
2-Pyridineacetamide, α-(2-(diisopropylamino)ethyl)-α-phenyl-
2-Pyridineacetamide, α-[2-(diisopropylamino)ethyl]-α-phenyl-
2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-
3737-09-5 (free base)
38236-46-3 [RN]
4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide
4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
4-[bis(methylethyl)amino]-2-phenyl-2-(2-pyridyl)butanamide
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanimidic acid
4-[di(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide
492056 [Beilstein]
4-Diisopropylamino-2-phenyl-2-(2-pyridyl)-butyramide
54687-36-4 [RN]
74464-83-8 [RN]
74464-84-9 [RN]
BS-17145
DB00280
Dicorantil
Disopiramida
Disopiramida [INN-Spanish]
Disopyramide-d5
Disopyramidum
Disopyramidum [INN-Latin]
MFCD00069254 [MDL number]
n-desalkyl Disopyramide
Norpace®
Ritmodan
Rythmodan P [Trade name]
Rythmodan®
Searle 703
α-(2-(Diisopropylamino)ethyl)-α-phenyl-2-pyridineacetamide
α-(2-(Diisopropylamino)ethyl)-α-phenyl-2-pyridineacetamide
α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-2-pyridineacetamide
γ-Diisopropylamino-α-phenyl-α-(2-pyridyl)butyramide
γ-Diisopropylamino-α-phenyl-α-(2-pyridyl)butyramide
дизопирамид
ديسوبيراميد
丙吡胺
DISOPYRAMIDE PHOSPHATE
Disopyramide phosphate is an organoammonium phosphate.
Disopyramide phosphate belongs to a group of medicines called anti-arrhythmic agents used to treat irregular heartbeats.
Disopyramide phosphate is available in both oral and intravenous forms and has a low degree of toxicity.

CAS Number: 3737-09-5
Molecular Formula: C21H29N3O
Molar Mass: 339.483 g·mol−1

Synonyms: Disopyramide PHOSPHATE, 22059-60-5, Norpace, Disopyramide PHOSPHATE SALT, Rythmodan, Norpace Cr, SC 7031 phosphate, Dirythmin sa, Diso-duriles, DisopyramidePhosphate, EINECS 244-756-1, SC 7031 (phosphate), NSC-756744, SC-13957, SC-7031 PHOSPHATE, CHEBI:4658, N6BOM1935W, 22059-60-5 (phosphate), SC 13957, Norpace (TN), 2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium phosphate, Disopyramid phosphate, 4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate, 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide;phosphoric acid, alpha-(2-Diisopropylaminoethyl)-alpha-phenyl-2-pyridineacetamide phosphate, (+-)-alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1), 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate, 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate (1:1), 2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl-, phosphate, alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1), 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, (+-)-, phosphate (1:1), SR-01000003039, Disopyramide (phosphate), UNII-N6BOM1935W, SCHEMBL41810, MLS000028431, SPECTRUM1500261, C21H29N3O.H3O4P, CHEMBL1201020, HMS501I11, DTXSID30944685, Disopyramide phosphate (JAN/USP), HMS1920I14, HMS2094K15, HMS2234B16, HMS3259J21, HMS3261C04, HMS3369L05, HMS3652M20, HMS3885J07, Pharmakon1600-01500261, Disopyramide PHOSPHATE [MI], XAA05960, Disopyramide PHOSPHATE [JAN], Tox21_500411, CCG-40209, Disopyramide PHOSPHATE [USAN], HY-12533A, NSC756744, Disopyramide PHOSPHATE [VANDF], AKOS040744844, Disopyramide PHOSPHATE [MART.], Disopyramide PHOSPHATE [USP-RS], Disopyramide PHOSPHATE [WHO-DD], LP00411, NC00683, NSC 756744, Disopyramide phosphate [USAN:BAN:JAN], NCGC00093836-01, NCGC00093836-02, NCGC00093836-03, NCGC00093836-04, NCGC00261096-01, SMR000058438, Disopyramide PHOSPHATE [ORANGE BOOK], LS-130131, Disopyramide PHOSPHATE [EP MONOGRAPH], Disopyramide phosphate [USAN:USP:BAN:JAN], EU-0100411, FT-0630479, S4143, SW196836-3, SW196836-4, Disopyramide PHOSPHATE [USP MONOGRAPH], C07740, D 6035, D00637, SR-01000003039-2, SR-01000003039-6, Q27106430, 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide, (R)-4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate, 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide,phosphoric acid, 4-DIISOPROPYLAMINO-2-PHENYL-2-(2-PYRIDYL)BUTYRAMIDE PHOSPHATE, Disopyramide phosphate, European Pharmacopoeia (EP) Reference Standard, Disopyramide phosphate, United States Pharmacopeia (USP) Reference Standard, (+/-)-.ALPHA.-(2-(DIISOPROPYLAMINO)ETHYL)-.ALPHA.-PHENYL-2-PYRIDINEACETAMIDE PHOSPHATE (1:1), 2-PYRIDINEACETAMIDE, .ALPHA.-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-.ALPHA.-PHENYL-, (+/-)-, PHOSPHATE (1:1), 223-110-2 [EINECS], 2-pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-phenyl-, 2-Pyridineacetamide, α-(2-(bis(1-methylethyl)amino)ethyl)-α-phenyl-, 2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl- [ACD/Index Name], 3737-09-5 [RN], 4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamid [German] [ACD/IUPAC Name], 4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamide [ACD/IUPAC Name], 4-(Diisopropylamino)-2-phényl-2-(2-pyridinyl)butanamide [French] [ACD/IUPAC Name], 4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramide, 4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide, 4-(dipropan-2-ylamino)-2-phenyl-2-(pyridin-2-yl)butanamide, a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide, a-[2-[Bis(1-methylethyl)amino]ethyl]a-phenyl-2-pyridineacetamide, disopiramida [Spanish] [INN], Disopyramide [French] [INN], Disopyramide [BAN] [INN] [JAN] [JP15] [USAN] [Wiki], Disopyramide, (R)-, Disopyramide, (S)-, disopyramidum [Latin] [INN], Isorythm, Lispine, MFCD00057366 [MDL number], Norpace [Trade name], Rythmodan [Trade name], α-[2-(DIISOPROPYLAMINO)ETHYL]-α-PHENYL-2-PYRIDINEACETAMIDE, α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide, дизопирамид [Russian] [INN], ديسوبيراميد [Arabic] [INN], 丙吡胺 [Chinese] [INN], Disopyramide free base, NORPACE CR, Rythmodan-La, ξ-Disopyramide, [3737-09-5] [RN], 1309283-08-6 [RN], 2-Pyridineacetamide, α-(2-(diisopropylamino)ethyl)-α-phenyl-, 2-Pyridineacetamide, α-[2-(diisopropylamino)ethyl]-α-phenyl-, 2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-, 3737-09-5 (free base), 38236-46-3 [RN], 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide, 4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide, 4-[bis(methylethyl)amino]-2-phenyl-2-(2-pyridyl)butanamide, 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide, 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanimidic acid, 4-[di(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide, 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide, 492056 [Beilstein], 4-Diisopropylamino-2-phenyl-2-(2-pyridyl)-butyramide, 54687-36-4 [RN], 74464-83-8 [RN], 74464-84-9 [RN], BS-17145, DB00280, Dicorantil, Disopiramida, Disopiramida [INN-Spanish], Disopyramide-d5, Disopyramidum, Disopyramidum [INN-Latin], MFCD00069254 [MDL number], n-desalkyl Disopyramide, Norpace®, Ritmodan, Rythmodan P [Trade name], Rythmodan®, Searle 703, α-(2-(Diisopropylamino)ethyl)-α-phenyl-2-pyridineacetamide, α-(2-(Diisopropylamino)ethyl)-α-phenyl-2-pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-2-pyridineacetamide, γ-Diisopropylamino-α-phenyl-α-(2-pyridyl)butyramide, γ-Diisopropylamino-α-phenyl-α-(2-pyridyl)butyramide, дизопирамид, ديسوبيراميد, 丙吡胺

Disopyramide phosphate is an antiarrhythmic chemical used in the treatment of ventricular tachycardia.
Disopyramide phosphate is a sodium channel blocker and is classified as a Class 1a anti-arrhythmic agent.

Disopyramide phosphate has a negative inotropic effect on the ventricular myocardium and significantly reduces contractility.
Disopyramide phosphate also has an anticholinergic effect on the heart, which is responsible for many negative side effects.
Disopyramide phosphate is available in both oral and intravenous forms and has a low degree of toxicity.

Disopyramide phosphate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only.
Disopyramide phosphate is used at industrial sites and in manufacturing.

Disopyramide phosphate is an organoammonium phosphate.

Disopyramide phosphate phosphate is a class Ia antiarrhythmic agent with cardiac depressant properties.
Disopyramide phosphate phosphate exerts Disopyramide phosphate actions by blocking both sodium and potassium channels in cardiac membrane during phase 0 of the action potential.

This slows the impulse conduction through the AV node and prolongs the duration of the action potential of normal cardiac cells in atrial and ventricular tissues.
Disopyramide phosphate prolongs the QT interval and causes a widening of the QRS complex.

Disopyramide phosphate also possesses some anticholinergic and local anaesthetic properties.
Disopyramide phosphate phosphate is used in the treatment of supraventricular tachycardia.

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine.
Disopyramide phosphate also possesses some anticholinergic and local anesthetic properties.

Disopyramide phosphate belongs to a group of medicines called anti-arrhythmic agents used to treat irregular heartbeats.
An irregular heartbeat is a condition in which your heart beats irregularly, too fast, or too slow.
Disopyramide phosphate helps slow the heart rate and prevent arrhythmias (abnormal heart rhythms).

Disopyramide phosphate contains Disopyramide phosphate, ie anti-arrhythmic agents.
Disopyramide phosphate helps bring irregular heartbeats to a normal rhythm by blocking certain electrical signals in the heart.
Irregular heartbeat treatment reduces the risk of blood clots, heart attack or stroke.

Disopyramide phosphate should be taken as prescribed by the doctor.
Your doctor may monitor EKGs and blood pressure during treatment to monitor your dose.

Some people may experience common side effects such as blurred or double vision, stomach pain, little or no urination, and low blood sugar.
Most of these side effects of Disopyramide phosphate do not require medical attention and will gradually improve over time.
However, if the side effects persist, please consult your doctor.

Please tell your doctor if you are known to be allergic to Disopyramide phosphate or any other medicines.
Disopyramide phosphate is not recommended for use in children.
Pregnant or breastfeeding women are advised to consult a doctor before taking Disopyramide phosphate.

Before taking Disopyramide phosphate, tell your doctor if you have kidney or liver disease, enlarged prostate, glaucoma (increased eye pressure) or low potassium levels in the blood (hypokalaemia).
Do not take Disopyramide phosphate if you are already taking other medicines to regulate your heartbeat.

Do not drive or operate machinery as Disopyramide phosphate may cause blurred vision, dizziness and low blood pressure.
Use Disopyramide phosphate with caution if you are elderly (over 65 years of age), have a low body weight, or have kidney or liver problems.

Disopyramide phosphate is used to treat certain irregular heartbeats).
Disopyramide phosphate is in a class of medications called antiarrhythmic drugs.
Disopyramide phosphate works by making your heart more resistant to abnormal activity.

Continuing Education Activity:
Disopyramide phosphate is a chemical used to treat heart rhythm abnormalities that can be life-threatening, such as ventricular tachycardia/fibrillation, or associated with increased morbidity and mortality, such as atrial fibrillation and hypertrophic cardiomyopathy.
This activity reviews several important aspects of this chemical, including indications, mechanism of action, applications, side effects, contraindications, monitoring, and toxicity.
This important knowledge of this chemical can improve interprofessional healthcare team outcomes.

Objectives:
Describe the mechanism of action of Disopyramide phosphate.
Describe possible side effects of Disopyramide phosphate.

Explains the importance of monitoring when using Disopyramide phosphate as an antiarrhythmic chemical.
Outline professional team strategies for improving care coordination and communication when using Disopyramide phosphate to maximize the benefits of this chemical and minimize Disopyramide phosphate side effects.

Indications:
In 1962, new antiarrhythmic drugs were needed apart from quinidine and procainamide, which were the main antiarrhythmic agents available at the time.
Disopyramide phosphate is the selected agent among more than 500 compounds synthesized for the research program of new antiarrhythmic agents.
The chemical structures of Disopyramide phosphate are similar to the synthetic muscarinic antagonist lacquer, which explains Disopyramide phosphate anticholinergic property.

Although Disopyramide phosphate is rarely used for heart rhythm abnormalities due to the availability of newer drugs that provide better efficacy and favorable side-effect profiles, Disopyramide phosphate is still the drug of choice for vagal-mediated atrial fibrillation such as sleep-induced or atrial fibrillation in athlete groups.
The effectiveness of Disopyramide phosphate in these conditions is due to Disopyramide phosphate anticholinergic activity, which abolishes the parasympathetic tone.

Disopyramide phosphate is also a third-line antiarrhythmic agent for a patient with coronary artery disease.
Also, a patient with left ventricular hypertrophy has impaired depolarization, which can induce torsade de pointes.

Therefore, antiarrhythmics that prolong the QT interval are avoided, but if sotalol or amiodarone is unsuccessful or unsuitable, Disopyramide phosphate may be an alternative.
In a patient with atrial fibrillation and hypertrophic obstructive cardiomyopathy (HOCM), Disopyramide phosphate is the agent of choice, other than amiodarone, as Disopyramide phosphate may decrease the left ventricular outflow tract (LVOT) gradient (off-label use).

Data from a multicenter study of the safety and efficacy of Disopyramide phosphate in obstructive cardiomyopathy showed that Disopyramide phosphate significantly reduced the SVOT gradient from 75+/- 33 to 40+/-32 mmHg in 78 patients (66% of study subjects) (P<0.0001). has shown. ) and raises the New York Heart Association functional class (NYHA FC) from 23+/-07 to 17+/-06 (P<0.0001).
When Disopyramide phosphate is used in combination with a non-dihydropyridine calcium channel blocker or beta blocker, they can effectively prevent recurrence of AF in HCOM patients.

Patients with ventricular premature beat (VPB) or premature ventricular complexes (PVC) may have a high symptom burden.
Disopyramide phosphate can be used in patients without structural heart disease, although Disopyramide phosphate efficacy is less than ablation.
In addition, based on a randomized, double-blind, placebo-controlled one-year follow-up study, Disopyramide phosphate (n=44) was effective in maintaining sinus rhythm after electro cardioversion for atrial fibrillation compared to placebo (n=46) and was significantly different (%) at one-month follow-up. 70 vs 39%) and continues after twelve months (54% vs 30%).

Uses of Disopyramide phosphate:
Disopyramide phosphate is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as sustained ventricular tachycardia).
Disopyramide phosphate is used to restore normal heart rhythm and maintain a regular, steady heartbeat.

Disopyramide phosphate is known as an anti-arrhythmic drug.
Disopyramide phosphate works by blocking certain electrical signals in the heart that can cause an irregular heartbeat.
Treating an irregular heartbeat can decrease the risk for blood clots, and this effect can reduce your risk of heart attack or stroke.

Usage of Disopyramide phosphate:
Disopyramide phosphate comes as a capsule and an extended-release (long-acting) capsule to take by mouth.
Disopyramide phosphate capsules may be taken every 6 or 8 hours.

The extended-release capsule is usually taken every 12 hours.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Take Disopyramide phosphate exactly as directed.
Do not take more or less of Disopyramide phosphate or take it more often than prescribed by your doctor.

Swallow the extended-release capsules; do not open, crush, or chew them.

Disopyramide phosphate helps control your condition but will not cure it.
Continue to take Disopyramide phosphate even if you feel well.
Do not stop taking Disopyramide phosphate without talking to your doctor.

Mechanism of action of Disopyramide phosphate:
Disopyramide phosphate's Class 1a activity is similar to that of quinidine in that Disopyramide phosphate targets sodium channels to inhibit conduction.
Disopyramide phosphate depresses the increase in sodium permeability of the cardiac myocyte during Phase 0 of the cardiac action potential, in turn decreasing the inward sodium current.

This results in an increased threshold for excitation and a decreased upstroke velocity.
Disopyramide phosphate prolongs the PR interval by lengthening both the QRS and P wave duration.

This effect is particularly well suited in the treatment of ventricular tachycardia as Disopyramide phosphate slows the action potential propagation through the atria to the ventricles.
Disopyramide phosphate does not act as a blocking agent for beta or alpha adrenergic receptors, but does have a significant negative inotropic effect on the ventricular myocardium.
As a result, the use of Disopyramide phosphate may reduce contractile force up to 42% at low doses and up to 100% in higher doses compared to quinidine.

Levites proposed a possible secondary mode of action for Disopyramide phosphate, against reentrant arrhythmias after an ischemic insult.
Disopyramide phosphate decreases the inhomogeneity between infarcted and normal myocardium refractory periods; in addition to lengthening the refractory period.

This decreases the chance of re-entry depolarization, because signals are more likely to encounter tissue in a refractory state which cannot be excited.
This provides a possible treatment for atrial and ventricular fibrillation, as Disopyramide phosphate restores pacemaker control of the tissue to the SA and AV nodes.

Pharmacology and Biochemistry of Disopyramide phosphate:

MeSH Pharmacological Classification:

Anti-Arrhythmia Agents:
Agents used for the treatment or prevention of cardiac arrhythmias.
They may affect the polarization-repolarization phase of the action potential, Disopyramide phosphate excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers.
Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.

Obstructive hypertrophic cardiomyopathy:
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease, occurring in 1:500 individuals in the general population.
Disopyramide phosphate is estimated that there are 600,000 individuals in the United States with hypertrophic cardiomyopathy.

The most common variant of HCM presents with left ventricular (LV) intracavitary obstruction due to systolic anterior motion of the mitral valve, and mitral-septal contact, diagnosed readily with echocardiography.
Pharmacologic treatment with negative inotropic drugs is first-line therapy.

Beta-blockers are used first, and while they improve symptoms of shortness of breath, chest pain and exercise intolerance, they do not reduce resting LV intraventricular pressure gradients and often are inadequate to control symptoms.
Many investigators and clinicians believe that Disopyramide phosphate controlled release is the most potent agent available for reducing resting pressure gradients and improving symptoms.

Disopyramide phosphate has been actively used for more than 30 years.
Disopyramide phosphate administration for obstructive HCM has a IB recommendation in the 2020 American Heart Association/American College of Cardiology Foundation guidelines for treatment of obstructive HCM.
A IB treatment recommendation indicates that a treatment is recommended, and may be useful, and beneficial.

Negative inotropes improve LV obstruction by decreasing LV ejection acceleration and hydrodynamic forces on the mitral valve.
Disopyramide phosphate's particular efficacy is due to Disopyramide phosphate potent negative inotropic effects; in head-to-head comparison, Disopyramide phosphate is more effective for gradient reduction than either beta-blocker or verapamil.

Disopyramide phosphate is most often administered with beta-blockade.
When used in patients resistant to beta-blockade, Disopyramide phosphate is effective in 60% of cases, reducing symptoms and gradient to the extent that invasive procedures such as surgical septal myectomy are not required.

Disopyramide phosphate, despite Disopyramide phosphate efficacy, has one main side effect that has limited Disopyramide phosphate use in the US, though Disopyramide phosphate has seen wider application in Canada, UK and Japan.
Vagal blockade predictably causes dry mouth, and in men with prostatism, may cause urinary retention.
Teichman et al. showed that pyridostigmine used in combination with Disopyramide phosphate substantially alleviates vagolytic side effects without compromising antiarrhythmic efficacy.

This combination has also been shown to be effective and safe in obstructive HCM in a large cohort of patients.
Some clinicians prescribe pyridostigmine sustained release (marketed in the US as Mestinon Timespan) to every patient begun on Disopyramide phosphate.
This combination increases acceptance of higher Disopyramide phosphate dosing, important since there is a dose-response correlation in obstructive HCM, higher doses yielding lower gradients.

Another concern about Disopyramide phosphate has been the hypothetical potential for inducing sudden death from Disopyramide phosphate type 1 anti-arrhythmic effects.
However, a multicenter registry and two recent cohort registries have largely reduced this concern, by showing sudden death rates lower than that observed from the disease itself.

These concerns about the drug must be viewed from the clinical perspective that Disopyramide phosphate is generally the last agent that is tried for patients before they are referred for invasive septal reduction with surgical septal myectomy (an open-heart operation) or alcohol septal ablation (a controlled heart attack).
Both of these invasive procedures have risk of morbidity and mortality.

For selected patients, a trial of oral Disopyramide phosphate is a reasonable approach before proceeding to invasive septal reduction.
Patients who respond to Disopyramide phosphate are continued on the drug.

Those who continue to have disabling symptoms or who experience side effects are promptly referred for septal reduction.
Using such a stepped strategy, investigators have reported that survival does not differ from that observed in the age-matched normal United States population.

Extracardiac effects:
Atropine like effects (anticholinergic)
Dry mouth
Constipation
Urinary retention – Disopyramide phosphate should not be given to patients with symptomatic prostatism.
Blurred vision
Glaucoma
Rash
Agranulocytosis

Additionally, Disopyramide phosphate may enhance the hypoglycaemic effect of gliclazide, insulin, and metformin.

Metabolism of Disopyramide phosphate:
Disopyramide phosphate can cause hypoglycemia, perhaps due to increased secretion of insulin, and can also potentiate the effects of conventional hypoglycemic drugs.
This effect may be due to Disopyramide phosphate chief metabolite mono-N dealkylDisopyramide phosphate, since many of the reported cases of hypoglycemia have been in patients with renal impairment, in which the metabolite accumulates.

In six subjects who were being considered for treatment with Disopyramide phosphate, serum glucose concentrations were measured at 13, 15, 17, and 19 hours after supper, with no further food, with and without the added administration of two modified-released tablets of Disopyramide phosphate 150 mg with supper and 12 hours later.
Disopyramide phosphate significantly reduced the serum glucose concentration at all measurement times by an average of 0.54 mmol/l.
The fall in serum glucose concentration was not related to the serum concentration of Disopyramide phosphate or the serum creatinine concentration; Disopyramide phosphate was greater in older patients and in underweight patients.

Hypoglycemia has also been reported in a 70-year-old woman with type 2 diabetes mellitus taking Disopyramide phosphate.

Clinical data of Disopyramide phosphate:
Trade names: Norpace
AHFS/Drugs.com: Monograph
MedlinePlus: a682408
Pregnancy category: AU: B2
Routes ofadministration: Oral, intravenous
ATC code: C01BA03 (WHO)

Legal status:
UK: POM (Prescription only)
US: ℞-only

Pharmacokinetic data of Disopyramide phosphate:
Bioavailability: High
Protein binding: 50% to 65% (concentration-dependent)
Metabolism: Hepatic (CYP3A4-mediated)
Elimination half-life: 6.7 hours (range 4 to 10 hours)
Excretion: Renal (80%)

Identifiers of Disopyramide phosphate:
IUPAC name: (RS)-4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
CAS Number: 3737-09-5
PubChem CID: 3114
IUPHAR/BPS: 7167
DrugBank: DB00280
ChemSpider: 3002
UNII: GFO928U8MQ
KEGG: D00303
ChEBI: CHEBI:4657
ChEMBL: ChEMBL517
CompTox Dashboard (EPA): DTXSID1045536
ECHA InfoCard: 100.021.010

Properties of Disopyramide phosphate:
Formula: C21H29N3O
Molar mass: 339.483 g·mol−1
Melting point: 94.5 to 95 °C (202.1 to 203.0 °F)
SMILES: O=C(N)C(c1ncccc1)(c2ccccc2)CCN(C(C)C)C(C)C
InChI: InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)
Key:UVTNFZQICZKOEM-UHFFFAOYSA-N

Molecular Weight: 437.5 g/mol
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 8
Exact Mass: 437.20795813 g/mol
Monoisotopic Mass: 437.20795813 g/mol
Topological Polar Surface Area: 137Ų
Heavy Atom Count: 30
Complexity: 459
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Names of Disopyramide phosphate:

Regulatory process names:
Disopyramide
Disopyramide

IUPAC names:
4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
Disopyramide

Other identifiers:
3737-09-5