Crop protection, Food, Feed and Flavor Chemicals

GUAR GUM 200 MESH

Guar gum 200 Mesh refers to Guar gum 200 Mesh that has been processed and ground to pass through a 200 mesh sieve.
Guar gum 200 Mesh itself is a natural polysaccharide derived from the seeds of the guar plant (Cyamopsis tetragonoloba).
Guar gum 200 Mesh consists primarily of high-molecular-weight polysaccharides composed of galactose and mannose units.

CAS Number: 9000-30-0
EC Number: 232-536-8

Synonyms:Guaran, Guaran gum, Guar flour, Guar bean gum, Cyamopsis gum, Cyamopsis tetragonoloba gum, Galactomannan, Galactomannose, JaGuar gum 200 Mesh, Cyamopsis tetragonolobus gum, Guaran gummi, Gomme de guar, Goma guar, Cyamopsis gummi, Cyamopsis tetragonolobus seed gum, Goma guar, Guaran seed gum, Guaran flour, Guaran gummi, Guaran endosperm gum, Guarane, Guarane flour, Guarane gum, Guarane seed gum, Guarane flour, Guarane gummi, Guarane endosperm gum, Guarane seed gum, Gomme guar, Gum guar, Gummi guar, Guar flour, Guar gum 200 Meshmi, Guaran gum, Guaran seed gum, Guaran flour, Guaran gummi, Guaran endosperm gum, Guaran seed gum, Guarane, Guarane flour



APPLICATIONS


Guar gum 200 Mesh is extensively used in the food industry as a thickening agent in a wide range of products including sauces, dressings, and condiments.
Guar gum 200 Mesh is a key ingredient in dairy products such as ice cream and yogurt, where it helps prevent ice crystallization and provides a smooth texture.
Guar gum 200 Mesh is commonly added to bakery products like bread and pastries to improve dough consistency and increase shelf life.
In the beverage industry, Guar gum 200 Mesh serves as a stabilizer, preventing separation and maintaining uniformity in drinks like fruit juices and smoothies.

Guar gum 200 Mesh is utilized in meat and poultry products as a binder, improving texture and reducing fat separation during cooking.
Guar gum 200 Mesh is used in pet food formulations to enhance texture and improve digestibility.
In the pharmaceutical industry, Guar gum 200 Mesh is employed as a binder in tablets and as a suspending agent in liquid medications.

Guar gum 200 Mesh is added to cosmetics and personal care products like lotions and creams to thicken formulations and enhance spreadability.
Guar gum 200 Mesh is used in the textile industry as a sizing agent, improving the strength and appearance of fabrics.
It serves as a thickening and gelling agent in the production of adhesives, providing improved tack and adhesion properties.
Guar gum 200 Mesh finds application in the mining industry as a flocculant in mineral processing, aiding in the separation of valuable minerals from ore.

Guar gum 200 Mesh is used in hydraulic fracturing (fracking) fluids in the oil and gas industry to thicken the fluid and carry proppants into fractures.
Guar gum 200 Mesh is added to paper coatings to improve printability and enhance surface smoothness.
In water treatment applications, Guar gum 200 Mesh is employed as a flocculant to aid in the removal of suspended solids from wastewater.

Guar gum 200 Mesh is used in the production of explosives as a binding agent, ensuring proper cohesion of explosive materials.
Guar gum 200 Mesh is added to household products like detergents and cleaners to improve viscosity and enhance performance.
In agriculture, Guar gum 200 Mesh is used as a soil conditioner to improve water retention and soil structure.

Guar gum 200 Mesh serves as a stabilizer and thickener in paints and coatings, improving application properties and film formation.
Guar gum 200 Mesh is utilized in the production of biodegradable films and packaging materials as a sustainable alternative to synthetic polymers.

Guar gum 200 Mesh is added to fire retardant materials to improve viscosity and prevent dripping during combustion.
Guar gum 200 Mesh finds application in the production of personal lubricants and intimate gels to enhance viscosity and lubricity.
In the construction industry, Guar gum 200 Mesh is used in cement and mortar formulations to improve workability and reduce water usage.

Guar gum 200 Mesh is employed in plant-based meat substitutes to improve texture and binding properties.
Guar gum 200 Mesh is utilized in the production of air fresheners and deodorizers to encapsulate and neutralize odors.
In the pharmaceutical industry, Guar gum 200 Mesh is used in controlled-release drug formulations to regulate drug release rates and enhance patient compliance.

Guar gum 200 Mesh is used in the production of dietary supplements and fiber products to promote digestive health and regulate bowel movements.
Guar gum 200 Mesh serves as a binding agent in plant-based meat analogs, helping to create a meat-like texture and hold ingredients together.

Guar gum 200 Mesh is added to frozen desserts such as ice cream and sorbet to improve creaminess and prevent crystallization.
In the pharmaceutical industry, it is used in oral suspensions to suspend insoluble drugs and improve palatability.
Guar gum 200 Mesh is added to toothpaste formulations to act as a thickening agent and improve the consistency of the product.
Guar gum 200 Mesh is used in the production of ceramic glazes to improve suspension and adhesion of pigments to the surface.

Guar gum 200 Mesh is utilized in the production of air freshener gels and beads to encapsulate fragrances and prolong release.
In the textile industry, it is used as a sizing agent to add body and stiffness to yarns and fabrics.
Guar gum 200 Mesh is added to hydraulic fracturing fluids in the oil and gas industry to improve viscosity and carry proppants into fractures.

Guar gum 200 Mesh serves as a thickening agent in printing inks to improve print definition and color intensity.
Guar gum 200 Mesh is used in the production of biodegradable plastics and films as a binder and film-forming agent.

Guar gum 200 Mesh is added to fertilizer formulations as a binder and dispersant to improve spreading and uptake by plants.
Guar gum 200 Mesh is employed in the production of fire extinguishing foams as a thickening agent to improve foam stability and coverage.
In the construction industry, it is used in the production of grouts and sealants to improve workability and adhesion.
Guar gum 200 Mesh is added to personal lubricants and intimate gels to enhance viscosity and provide long-lasting lubrication.

Guar gum 200 Mesh serves as a stabilizer and emulsifier in emulsion explosives to improve stability and detonation properties.
Guar gum 200 Mesh is used in the production of dietary fiber supplements to increase fiber content in the diet and promote satiety.
In the agricultural sector, it is added to soil stabilizers and erosion control products to improve soil structure and prevent erosion.

Guar gum 200 Mesh is employed in the production of biodegradable diapers and sanitary products as a superabsorbent material.
Guar gum 200 Mesh serves as a binder in the production of carbonless copy paper to improve cohesion between paper layers.
Guar gum 200 Mesh is added to firefighting foams as a thickening agent to improve foam stability and extinguishing properties.

In the ceramics industry, it is used as a suspending agent in glazes to prevent settling and improve application properties.
Guar gum 200 Mesh is added to oil-based drilling fluids to increase viscosity and improve hole-cleaning efficiency.
Guar gum 200 Mesh serves as a stabilizer in latex paints to prevent settling and improve shelf life.
Guar gum 200 Mesh is used in the production of plant-based milk alternatives such as almond or oat milk to improve texture and mouthfeel.



DESCRIPTION


Guar gum 200 Mesh refers to Guar gum 200 Mesh that has been processed and ground to pass through a 200 mesh sieve.
Guar gum 200 Mesh itself is a natural polysaccharide derived from the seeds of the guar plant (Cyamopsis tetragonoloba).
Guar gum 200 Mesh consists primarily of high-molecular-weight polysaccharides composed of galactose and mannose units.

The "200 Mesh" designation indicates the particle size of the Guar gum 200 Mesh powder.
Mesh size is a measure of the number of openings per linear inch in a sieve through which particles can pass.
In this case, Guar gum 200 Mesh 200 Mesh means that the powder has been finely ground to pass through a sieve with 200 openings per linear inch.

Guar gum 200 Mesh is commonly used in various industries such as food, pharmaceuticals, cosmetics, and textiles for its thickening, stabilizing, and emulsifying properties.
The finely ground powder allows for better dispersion and incorporation into formulations, making it suitable for a wide range of applications.

Guar gum 200 Mesh is a natural polysaccharide extracted from the seeds of the guar plant (Cyamopsis tetragonoloba).
Guar gum 200 Mesh is commonly found in the form of a fine, white to yellowish powder.
The texture of Guar gum 200 Mesh powder is smooth and powdery, resembling finely ground flour.

Guar gum 200 Mesh has a neutral odor and a bland taste, making it suitable for various applications in the food industry.
When hydrated, Guar gum 200 Mesh forms viscous solutions or gels, depending on the concentration.
The viscosity of Guar gum 200 Mesh solutions can range from relatively low to highly viscous, depending on the desired consistency.

Guar gum 200 Mesh is highly soluble in water, forming clear and transparent solutions.
Guar gum 200 Mesh has excellent thickening properties, making it ideal for use in soups, sauces, and gravies.
Guar gum 200 Mesh is often used as a stabilizer in dairy products to prevent syneresis and improve texture.

Due to its emulsifying properties, Guar gum 200 Mesh helps to create smooth and creamy textures in various food products.
Guar gum 200 Mesh is resistant to degradation by enzymes and acids, making it suitable for use in acidic formulations.

Guar gum 200 Mesh has a high swelling capacity, absorbing water to form viscous solutions or gels.
Guar gum 200 Mesh is compatible with a wide range of pH levels, making it versatile in different formulations.

Guar gum 200 Meshis commonly used as a binding agent in gluten-free baking to improve dough consistency.
Guar gum 200 Mesh is often added to frozen desserts to prevent ice crystal formation and improve mouthfeel.
In pharmaceutical formulations, Guar gum 200 Mesh is used as a binder in tablets and a suspending agent in liquid medications.

Guar gum 200 Meshis used in the cosmetic industry as a thickening agent in lotions, creams, and shampoos.
Guar gum 200 Mesh is biodegradable and environmentally friendly, making it an attractive option for sustainable products.

Guar gum 200 Meshis known for its stability and long shelf life when stored properly in sealed containers.
Guar gum 200 Mesh is often included in dietary supplements and fiber products to promote digestive health.
Due to its non-toxic nature, Guar gum 200 Mesh is generally recognized as safe (GRAS) for consumption in food and pharmaceutical applications.
Guar gum 200 Mesh has a slightly grainy texture when mixed with water, but it disperses easily to form smooth solutions.

Guar gum 200 Meshis commonly used as a thickening and stabilizing agent in a variety of industrial applications, including textiles, papermaking, and mining.
Guar gum 200 Mesh is valued for its ability to improve the texture, mouthfeel, and shelf life of food and non-food products.
Guar gum 200 Mesh is a versatile ingredient with a wide range of applications, contributing to the functionality and quality of numerous consumer products.



PROPERTIES


Physical Properties:

Appearance: Fine, white to yellowish powder
Odor: Odorless or faint characteristic odor
Taste: Virtually tasteless
Solubility: Soluble in cold and hot water, insoluble in most organic solvents
Density: Approximately 0.8-1.2 g/cm³
Particle Size: Typically ranges from 100 to 300 mesh
pH: Neutral to slightly acidic (pH around 6-7 in aqueous solution)
Viscosity: Forms highly viscous solutions or gels when hydrated
Hygroscopicity: Absorbs water readily, forming viscous solutions or gels
Melting Point: Decomposes at high temperatures without melting
Boiling Point: Decomposes before boiling
Flammability: Non-flammable and non-combustible
Stability: Stable under normal storage conditions, but may degrade over time with exposure to heat, moisture, or high pH.


Chemical Properties:

Chemical Formula: Variable; complex mixture of polysaccharides
Chemical Structure: Linear polymer consisting of mannose and galactose units linked by glycosidic bonds
Functional Groups: Hydroxyl (-OH) groups on the sugar units
Hydrophilicity: Hydrophilic due to the presence of numerous hydroxyl groups
Molecular Weight: Typically ranges from 100,000 to 2,000,000 g/mol depending on the degree of polymerization
Degree of Substitution: Varies depending on the source and processing methods
Solubility in Water: Forms colloidal solutions or gels upon hydration
Swelling Capacity: Swells in water to form viscous solutions or gels due to hydration of polymer chains
Ionic Properties: Can be modified to introduce ionic character through chemical derivatization



FIRST AID


Inhalation:

If inhalation of Guar gum 200 Mesh dust or particles occurs and respiratory irritation develops, remove the affected person to fresh air immediately.
Allow the individual to rest in a well-ventilated area.
If breathing difficulties persist, seek medical attention promptly.


Skin Contact:

In case of skin contact with Guar gum 200 Mesh powder or solutions, promptly remove contaminated clothing and rinse the affected area with plenty of water.
Wash the skin thoroughly with mild soap and water to remove any residue.
If irritation, redness, or rash develops, seek medical advice.


Eye Contact:

If Guar gum 200 Mesh powder or solutions come into contact with the eyes, immediately flush the eyes with lukewarm water for at least 15 minutes, ensuring that eyelids are held open to facilitate thorough rinsing.
Seek immediate medical attention if irritation, pain, or redness persists.


Ingestion:

If Guar gum 200 Mesh is ingested accidentally and the individual is conscious, rinse the mouth thoroughly with water to remove any remaining substance.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek medical advice or assistance immediately, and provide relevant information such as the amount ingested and the individual's symptoms.


General First Aid:

If any symptoms persist or worsen after exposure to Guar gum 200 Mesh, seek medical attention promptly.
Provide first aid responders with Safety Data Sheets (SDS) or product information for proper assessment and treatment guidance.
Do not administer any medication or treatment without professional medical advice.
Keep the affected individual calm and reassured during first aid procedures.


Additional Information:

Guar gum 200 Mesh is generally considered low in toxicity, but individual sensitivity may vary.
Avoid contact with eyes, skin, and mucous membranes as much as possible to prevent irritation.
If Guar gum 200 Mesh is used in industrial settings, ensure that appropriate personal protective equipment (PPE) is worn to minimize exposure.
Follow all safety precautions and guidelines provided by manufacturers and regulatory agencies for safe handling and use of Guar gum 200 Mesh.
Store Guar gum 200 Mesh products securely in sealed containers and away from incompatible materials to prevent accidental exposure.
In case of emergency, contact local poison control centers or healthcare professionals for further assistance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate personal protective equipment (PPE) such as safety goggles, gloves, and protective clothing when handling Guar gum 200 Mesh to minimize skin and eye contact.
Use respiratory protection (e.g., dust mask) if working with Guar gum 200 Mesh powder to prevent inhalation of dust particles.

Ventilation:
Ensure adequate ventilation in the handling area to minimize exposure to airborne dust or vapors.
Use local exhaust ventilation systems or mechanical ventilation to remove airborne contaminants.

Handling Precautions:
Avoid generating dust when handling Guar gum 200 Mesh powder by using dust suppression techniques such as dampening or containment.
Use appropriate handling equipment (e.g., scoops, shovels) to minimize spills and dust generation.
Avoid eating, drinking, or smoking in areas where Guar gum 200 Mesh is handled to prevent accidental ingestion or inhalation.

Spill and Leak Procedures:
Clean up spills or leaks of Guar gum 200 Mesh promptly to prevent contamination and minimize the risk of slips and falls.
Use absorbent materials (e.g., vermiculite, sand) to contain and absorb spills, then dispose of according to local regulations.
Avoid washing Guar gum 200 Mesh residues directly into drains or waterways to prevent environmental contamination.

Fire and Explosion Hazards:
Guar gum 200 Mesh is non-flammable and non-combustible under normal conditions.
However, avoid exposure to high temperatures or sources of ignition as it may decompose and release hazardous gases.


Storage:

Storage Conditions:
Store Guar gum 200 Mesh in a cool, dry, well-ventilated area away from direct sunlight and heat sources.
Keep containers tightly closed when not in use to prevent contamination and moisture ingress.
Ensure storage areas are clean, organized, and free from potential sources of contamination.

Temperature Control:
Maintain storage temperature within the recommended range to prevent degradation or changes in properties.
Avoid exposure to extreme temperatures, as high temperatures can cause Guar gum 200 Mesh to degrade or lose functionality.

Container Compatibility:
Store Guar gum 200 Mesh in containers made of compatible materials such as high-density polyethylene (HDPE), polypropylene (PP), or glass.
Ensure containers are labeled with relevant hazard warnings and handling instructions for easy identification.

Protection from Contamination:
Prevent cross-contamination by storing Guar gum 200 Mesh away from incompatible materials such as strong acids, alkalis, or oxidizing agents.
Keep storage areas clean and free from dust, dirt, or other foreign particles that may contaminate the product.

Handling Precautions:
Handle containers with care to prevent damage or leakage.
Do not stack heavy objects on top of Guar gum 200 Mesh containers to avoid deformation or breakage.
Use appropriate material handling equipment (e.g., pallets, forklifts) to transport and store Guar gum 200 Mesh safely.

GUAR GUM 200 MESH
Guar gum 200 mesh, also called guaran, is a galactomannan polysaccharide extracted from guar beans that has thickening and stabilizing properties useful in food, feed, and industrial applications.
Guar gum 200 mesh acts as a binder in meat.
Guar gum 200 mesh is also a good source of dietary fibre (80% on a dry weight basis) and an additive in animal food, including pet food.

CAS Number: 9000-30-0
Molecular Formula: C10H14N5Na2O12P3
Molecular Weight: 535.145283
EINECS Number: 232-536-8

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Guar gum 200 mesh is the endosperm of the seed of the Indian cluster bean, Cyamopsis tetragonolobus.
Guar gum 200 mesh has been grown for several thousand years in India and Pakistan as a vegetable and a forage crop.
Guar gum 200 mesh is a hardy and drought-resistant plant, which grows 1 to 2 m high with vertical stalks and resembles the soybean plant in general appearance.

Guar gum 200 mesh pods, which grow in clusters along the vertical stems, are about 30 cm long and contain six to nine seeds, which are considerably smaller than locust bean seeds Guar gum is odorless.
As in the case of locust bean Guar gum 200 mesh, the endosperm, which comprises 35 to 42% of the seed, is the source of the gum Typically, guar gum is around 80% of the endosperm of the guar seed.
As the endosperm is about 40% of the seed, Guar gum 200 mesh is roughly 30% of the guar plant seed.

Guar gum 200 mesh is harvested before the frst rain following the frst frost to obtain maximum yield and purity (Burdock, 1997).
Guar gum 200 mesh as a gum obtained from the ground endosperms of Cyamopsis tetragonolobus (L.) Taub.
Guar gum 200 mesh consists chiefly of a high-molecular-weight hydrocolloidal polysaccharide, composed of galactan and mannan units combined through glycoside linkages, which may be described chemically as a galactomannan.

The main components are polysaccharides composed of Dgalactose and D-mannose in molecular ratios of 1 : 1.4 to 1 : 2.
The molecule consists of a linear chain of b-(1!4)-glycosidically linked manno-pyranoses and single a-(1→6)-glycosidically linked galactopyranoses.
Guar gum 200 mesh is yish-white free-flowing powder.

Completely soluble in hot or cold water.
Practically insoluble in oils, greases, hydrocarbons, ketones, esters.
Water solutions are tasteless, odorless, nontoxic.

Guar gum 200 mesh reduces the friction drag of water on metals.
Guar gum 200 mesh is a white to yellowish-white powder.
Guar gum 200 mesh is dispersible in either hot or cold water, forming a solution having a pH between 5.4 and 7.0 that may be converted to gel by the addition of a small amount of sodium borate.

Guar gum 200 mesh bean is principally grown in India, Pakistan, the United States, Australia and Africa.
India is the largest producer, accounting for nearly 80% of the world production.
In India, Rajasthan, Gujarat, and Haryana are the main producing regions.

The US has produced 4,600 to 14,000 tonnes of guar over the last 5 years.
Texas acreage since 1999 has fluctuated from about 7,000 to 50,000 acres.
The world production for Guar gum 200 mesh and its derivatives is about 1.0 million tonnes.

Non-food guar gum accounts for about 40% of the total demand.
Food grade Guar Gum Powder is a natural, plant-based, soluble fiber that is derived from the seed of the guar plant.
Guar gum 200 mesh is commonly used as a thickening, stabilizing, and emulsifying agent in a wide range of food and beverage applications.

Some of the popular food products that contain guar gum powder include ice cream, baked goods, sauces, dressings, soups, and beverages.
The food grade guar gum powder is known for its ability to enhance the texture, viscosity, and shelf life of food products.
Guar gum 200 mesh is also gluten-free, non-GMO, and vegan, making it an ideal ingredient for various dietary requirements.

Guar gum 200 mesh is a ether-alcohol derivative, the ether being relatively unreactive.
Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents.
They react with oxoacids and carboxylic acids to form esters plus water.

Oxidizing agents convert alcohols to aldehydes or ketones.
Alcohols exhibit both weak acid and weak base behavior.
They may initiate the polymerization of isocyanates and epoxides.

Guar gum 200 mesh is an exo-polysaccharide composed of the sugars galactose and mannose.
The backbone is a linear chain of β 1,4-linked mannose residues to which galactose residues are 1,6-linked at every second mannose, forming short side-branches.
Guar gum 200 mesh has the ability to withstand temperatures of 80 °C (176 °F) for five minutes.

Guar gum 200 mesh is more soluble than locust bean gum due to its extra galactose branch points.
Unlike locust bean Guar gum 200 mesh, it is not self-gelling.
Either borax or calcium can cross-link Guar gum 200 mesh, causing it to gel.

In water, Guar gum 200 mesh is nonionic and hydrocolloidal.
Guar gum 200 mesh is not affected by ionic strength or pH, but will degrade at extreme pH and temperature (e.g. pH 3 at 50 °C).
Guar gum 200 mesh remains stable in solution over pH range 5–7.

Strong acids cause hydrolysis and loss of viscosity and alkalies in strong concentration also tend to reduce viscosity.
Guar gum 200 mesh is insoluble in most hydrocarbon solvents.
The viscosity attained is dependent on time, temperature, concentration, pH, rate of agitation and particle size of the powdered gum used.

The lower the temperature, the lower the rate at which viscosity increases, and the lower the final viscosity.
Above 80°, the final viscosity is slightly reduced.
Finer guar powders swell more rapidly than larger particle size coarse powdered gum.

Guar gum 200 mesh shows a clear low shear plateau on the flow curve and is strongly shear-thinning.
The rheology of Guar gum 200 mesh is typical for a random coil polymer.
Guar gum 200 mesh does not show the very high low shear plateau viscosities seen with more rigid polymer chains such as xanthan gum.

Guar gum 200 mesh is very thixotropic above 1% concentration, but below 0.3%, the thixotropy is slight.
Guar gum 200 mesh shows viscosity synergy with xanthan gum.
Guar gum 200 mesh and micellar casein mixtures can be slightly thixotropic if a biphase system forms.

Guar gum 200 mesh is a naturally occurring polysaccharide.
Guar gum 200 mesh contains galactose and mannan units.
Guar gum 200 mesh is widely used in various industries such as food, personal care, and pharmaceuticals.

Guar gum 200 mesh has an average molecular weight of 220 kDa.
Guar gum 200 mesh is composed of about 80% guaran.
Guar gum 200 mesh is commonly used in pharmaceuticals and cosmetics as a thickening and emulsifier.

Guar gum 200 mesh is a good source of soluble dietary fiber.
Guar gum 200 mesh is useful in maintaining intestinal function and cleansing the digestive system.
Guar gum 200 mesh is also useful in treating diabetes and obesity.

Guar gum 200 mesh has high water-holding capacity in hot water.
Guar gum 200 mesh solutions are stable in a wide pH range.
Guar gum 200 mesh is also used as a suspension stabilizer and gelling agent.

Guar gum 200 mesh is also used in cosmetics, beverages, and fracking industries.
Guar gum 200 mesh is an odorless polysaccharide.
Guar gum 200 mesh is used in food industry, cosmetic industry, and pharmaceutical industry as a thickening agent, emulsifier, and gelling agent.

Guar gum 200 mesh is one of the highest molecular weight polymers.
Guar gum 200 mesh is also used in water phase control in various industries.
Guar gum 200 mesh is gluten-free, making it a valuable ingredient in gluten-free and low-gluten products as a substitute for traditional thickeners and stabilizers.

Guar gum 200 mesh is used in the production of bread, cakes, and other baked goods to improve dough consistency, increase water retention, and enhance shelf life.
Guar gum 200 mesh is commonly used in the production of dairy products, such as yogurt and ice cream, to provide stability, prevent ice crystal formation, and improve texture.
Guar gum 200 mesh is employed in the formulation of sauces and dressings to enhance viscosity, stability, and overall product quality.

Guar gum 200 mesh is used in certain beverages, including fruit juices and fruit-flavored drinks, to improve mouthfeel and prevent settling of particulate matter.
Guar gum 200 mesh is used in the pet food industry to achieve desired textures and improve the palatability of pet food products.
Guar gum 200 mesh is utilized in canned and processed foods to enhance the stability of suspensions and emulsions, preventing separation of ingredients.

Due to its ability to absorb water and create a feeling of fullness, Guar gum 200 mesh is sometimes used in weight control products and high-fiber foods.
Guar gum 200 mesh is also used as a laxative, foam stabilizer, and film-forming agent.
Guar gum 200 mesh is used to treat diarrhea.

Guar gum 200 mesh is a natural thickener and emulsifier with superior thickening and stabilizing properties.
Guar gum 200 mesh is found in a wide variety of cosmetics and food products.
Guar gum 200 mesh is widely used in shaving creams, lotions, deodorants, and toothpastes.

Guar gum 200 mesh is also used in the paper, pharmaceutical, and oil well drilling industries.
Guar gum 200 mesh powder in cosmetics is an economical option.
Guar gum 200 mesh is produced from high quality ingredients, and it is guaranteed for non-allergic properties.

Guar gum 200 mesh is ideal for use in emulsified systems, which helps to improve the shelf life of skin care products.
Guar gum 200 mesh also helps to prevent water loss and minimizes syneresis.
Guar gum 200 mesh is the leading producer of guar gum powder in the United States.

Guar gum 200 mesh powder is completely safe to use, and it has been approved by the Food and Drug Administration.
Guar gum 200 mesh can be used in an aqueous solution without heating, and it will also suspend solids.
Guar gum 200 mesh powder can also be used to adjust the viscosity of aqueous solutions.

Guar gum 200 mesh also minimizes friction from static charges, which helps to avoid separation of liquid from gel.
Guar gum 200 mesh is extracted from guar beans, which are primarily grown in India, Pakistan, the United States, and several other countries.
Guar gum 200 mesh plant is an annual legume.

Guar gum 200 mesh is a polysaccharide composed of galactose and mannose units.
Guar gum 200 mesh belongs to the family of galactomannans.
The molecular structure of Guar gum 200 mesh imparts its thickening and stabilizing properties.

The guar seeds are mechanically dehusked, hydrated, milled and screened according to application.
Guar gum 200 mesh is typically produced as a free-flowing, off-white powder.
Guar gum 200 mesh is white to light yellowish.

Guar gum 200 mesh form viscous liquid after dispersing in hot or cold water.
The viscosity of 1% aqueous solution is about 4~5Pa which is the highest viscosity in natural rubber.
After adding small amount of sodium tetraborate Guar gum 200 mesh changes to gel.

After dispersing in cold water for about 2h Guar gum 200 mesh shows strong viscosity and the viscosity gradually increases reached the highest point after 24h.
Guar gum 200 mesh is viscosity is 5 to 8 times than that of starch and quickly reaches the highest point under heat.
The aqueous solution is neutral.The viscosity is highest with pH between 6 and 8 and substantially decreases when pH is above.

And viscosity decreases sharply along with pH value dropping when pH value is 6.0 to 3.5. The viscosity below 3.5 increases again.
The source of Guar gum 200 mesh, Cyamopsis tetragonolobus, is widely grown in Pakistan and India as cattle feed, and was introduced to the United States as a cover crop in 1903.
Guar gum 200 mesh was not until 1953, however, that guar gum was produced on a commercial scale, primarily as a replacement for locus bean gum in the paper, textile and food industries.

The most important property of guar is the ability to hydrate rapidly in cold water to attain a very high viscosity.
In addition to the food industry, Guar gum 200 mesh is used in the mining, paper, textile, ceramic, paint, cosmetic, pharmaceutical, explosive, and other industries.
Guar gum 200 mesh is a hardy and drought-resistant plant which grows three to six feet high with vertical stalks.

Guar gum 200 meshs, which grow in clusters along the vertical stems, are about six inches long and contain 6 to 9 seeds, which are considerably smaller than locus bean seeds.
As in the case of locust bean Guar gum 200 mesh, the endosperm, which comprises 35-42%.
Guar gum 200 mesh is a white to yellowish white powder and is nearly odorless.

Fine finished Guar gum 200 mesh Powder is available in different viscosities and granulometries depending on the desired viscosity development and applications.
Guar gum 200 mesh is a natural high molecular weight hydrocolloidal polysaccharide composed of galactan and mannan units combined through glycosidic linkages, which may be described chemically as galactomannan.
Guar gum 200 mesh is a cold water soluble polysaccharide, consisting of mannose and galactose units.

This ability to hydrate without heating makes Guar gum 200 mesh very useful in many industrial and food applications.
Dissolved in cold or hot water, Guar gum 200 mesh forms a slime of high viscosity.
Guar gum 200 mesh's viscosity is a function of temperature, time, and concentration.

Solutions with different Guar gum 200 mesh concentrations can be used as emulsifiers and stabilizers because they prevent oil droplets from coalescing.
Guar gum 200 mesh is also used as suspension stabilizer.
Guar gum 200 mesh is derived from the ground endosperm of guar beans.

Guar gum 200 mesh plant, Cyanmopsis tetragonoloba, is mainly grown in India, but also Pakistan, the US, Australia and Africa.
Guar gum 200 mesh is obtained after the beans are de-husked, milled and sieved.
Guar gum 200 mesh is sold as an off-white powder and forms a gel when dissolved in water (hydrocolloid) and mixed with borax or calcium.

Guar gum 200 mesh is an effective thickener as only a small quantity (1% concentration) is required to form a viscous solution, although its viscosity reduces at lower temperatures or when vigorously shaken.
Guar gum 200 mesh powder is available in high and medium visocity grades. Guar gum also acts as a stabiliser (it prevents solid particles in a liquid from settling) and an emulsifier (it prevents oil droplets from coalescing).
Guar gum 200 mesh remains stable in solution over a pH range of 5-7.

Guar gum 200 mesh may have synergistic effects with Xanthan gum, Locust Bean gum and Sodium Alginate.
Guar gum 200 mesh powder grades categorized in two are food grade and industrial grade powder.
Guar gum 200 mesh occurs as an odorless or nearly odorless, white to yellowish-white powder with a bland taste.

Guar gum 200 mesh, often referred to as guaran, is a food-grade substance derived from guar beans, which are the seeds of the guar plant (Cyamopsis tetragonoloba).
Guar gum, like locust bean gum, is a galactomannan derived from the seed of a leguminous plant.

Melting point: >220°C (dec.)
alpha: D25 +53° (1N NaOH)
FEMA: 2537 | GUAR GUM (CYAMOPSIS TETRAGONOLOBUS (L.))
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: It yields a mucilage of variable viscosity when dissolved in water, practically insoluble in ethanol (96 per cent).
form: Free Flowing Powder
color: Yellow-white
Odor: Odorless
Viscosity: 350 to 700 mPa-s(1 %, H2O, 20 ℃, calcd.on dried substance)
Merck: 13,4588 / 13,4587
Stability: Stable. Combustible. A mixture of air and finely-divided powder is potentially explosive. Incompatible with strong oxidizing agents.

Guar gum 200 mesh is employed in the formulation of sauces and dressings to enhance viscosity, stability, and overall product quality.
Guar gum 200 mesh molecules have a tendency to aggregate during the hydraulic fracturing process, mainly due to intermolecular hydrogen bonding.
Guar gum 200 mesh is obtained from the ground endosperm of the guar plant, Cyamopsis tetragonolobus (L.) Taub. (Fam. Leguminosae), which is grown in India, Pakistan, and the semiarid southwestern region of the USA.

The seed hull can be removed by grinding, after soaking in sulfuric acid or water, or by charring.
The embryo (germ) is removed by differential grinding, since each component possesses a different hardness.
The separated endosperm, containing 80% galactomannan is then ground to different particle sizes depending upon final application.

Guar gum 200 mesh is a thickening agent in foods and medicines for humans and animals.
Because it is gluten-free, Guar gum 200 mesh is used as an additive to replace wheat flour in baked goods.
Guar gum 200 mesh has been shown to reduce serum cholesterol and lower blood glucose levels.

Guar gum 200 mesh is also economical because it has almost eight times the water-thickening ability of other agents (e.g. cornstarch) and only a small quantity is needed for producing sufficient viscosity.
Guar gum 200 mesh's effects on viscosity, its high ability to flow, or deform, gives it favorable rheological properties.
Guar gum 200 mesh forms breakable gels when cross-linked with boron.

Guar gum 200 mesh is used in various multi-phase formulations for hydraulic fracturing, in some as an emulsifier because it helps prevent oil droplets from coalescing, and in others as a stabilizer to help prevent solid particles from settling and/or separating.
Guar gum 200 mesh retards ice crystal growth by slowing mass transfer across the solid/liquid interface.
Guar gum 200 mesh shows good stability during freeze-thaw cycles.

Thus, Guar gum 200 mesh is used in egg-free ice cream.
Guar gum 200 mesh has synergistic effects with locust bean gum and sodium alginate.
May be synergistic with xanthan: together with xanthan gum, it produces a thicker product (0.5% guar gum / 0.35% xanthan gum), which is used in applications such as soups, which do not require clear results.

Guar gum 200 mesh is a hydrocolloid, hence is useful for making thick pastes without forming a gel, and for keeping water bound in a sauce or emulsion.
Guar gum 200 mesh can be used for thickening cold and hot liquids, to make hot gels, light foams and as an emulsion stabilizer.
Guar gum 200 mesh can be used for cottage cheeses, curds, yoghurt, sauces, soups and frozen desserts.

Guar gum 200 mesh is also a good source of fiber with 80% soluble dietary fiber on a dry weight basis.
Using food grade Guar gum 200 mesh powder in ice cream stabilization is increasing as the market for organic ice cream grows.
Guar gum 200 mesh powder is an organic stabilizer, which can thicken and improve the texture and body of ice cream.

Guar gum 200 mesh also improves the heat shock resistance of the product and helps maintain the creamy texture of reduced calorie dairy products.
Guar gum 200 mesh is extracted from the seeds of the guar plant.
Guar gum 200 meshs are preferred as thickeners for enhanced oil recovery (EOR).

Guar gum 200 mesh and its derivatives account for most of the gelled fracturing fluids.
Guar gum 200 mesh is more water-soluble than other gums, and it is also a better emulsifier, because it has more galactose branch points.
Guar gum 200 mesh shows high low-shear viscosity, but it is strongly shear-thinning.

Being non-ionic, Guar gum 200 mesh is not affected by ionic strength or pH but will degrade at low pH at moderate temperature (pH 3 at 50 °C).
Guar gum 200 mesh's derivatives demonstrate stability in high temperature and pH environments.
Guar gum 200 mesh use allows for achieving exceptionally high viscosities, which improves the ability of the fracturing liquid to transport proppant.

Guar gum 200 mesh hydrates fairly rapidly in cold water to give highly viscous pseudoplastic solutions of, generally, greater low-shear viscosity than other hydrocolloids.
The colloidal solids present in guar make fluids more efficient by creating less filter cake.
Proppant pack conductivity is maintained by utilizing a fluid that has excellent fluid loss control, such as the colloidal solids present in Guar gum 200 mesh.

Guar gum 200 mesh has up to eight times the thickening power of starch.
Derivatization of guar gum leads to subtle changes in properties, such as decreased hydrogen bonding, increased solubility in water-alcohol mixture, and improved electrolyte compatibility.
These changes in properties result in increased use in different fields, like textile printing, explosives, and oil-water fracturing applications.

Guar gum 200 mesh is compatible with most other plant hydrocolloids such as tragacanth.
Guar gum 200 mesh is used in certain beverages, including fruit juices and fruit-flavored drinks, to improve mouthfeel and prevent settling of particulate matter.
Guar gum 200 mesh is used in the pet food industry to achieve desired textures and improve the palatability of pet food products.

Uses:
Guar gum 200 mesh is used as binder or disintegrator in tablets.
Guar gum 200 mesh can be used in inkjet printing inks to improve the viscosity and stability of the ink formulations.
Guar gum 200 mesh can be used for cake making, producing gluten free food, bread making, ice-cream making and a gluten free thickener.

Guar gum 200 mesh is used during the preparation of lotions and creams.
Guar gum 200 mesh is often used by pharmaceutical companies to help bind tablets.
Guar gum 200 mesh has been linked to a reduction in serum cholesterol having a positive effect on blood glucose.

Guar gum 200 mesh is used as a binder in the pharmaceutical industry for tablets production.
Guar gum 200 mesh is a thickening agent in textile printing, sizing, and finishing.
In the mining industry, Guar gum 200 mesh is a froth or coagulation agent in ore processing as it is regarded as eco-friendly.

Guar gum 200 mesh a mineral depressant especially in talc, calcite, and lead mining, also it is vital in copper-lead separation.
Guar gum 200 mesh is used in water treatment and recycling, that is as Flocculation agent.
In addition, Guar gum 200 mesh is used in the petroleum industry especially in drilling mud and fracturing fluids.

Guar gum 200 mesh is a thickener in slurry-based explosives.
In the cosmetics industry, Guar gum 200 mesh is a mixture stabilizer and surfactant.
Guar gum 200 mesh is commonly used as a thickening agent in various food products such as sauces, dressings, soups, and gravies.

Guar gum 200 mesh imparts viscosity and improves the texture of these formulations.
Guar gum 200 mesh helps stabilize and emulsify certain food products, preventing the separation of ingredients in items like salad dressings and ice creams.
In gluten-free baking, Guar gum 200 mesh is used as a binder and thickener to provide structure and improve the texture of baked goods.

Guar gum 200 mesh is employed in hydraulic fracturing (fracking) fluids in the oil and gas industry.
Guar gum 200 mesh helps to carry proppants into fractures and enhances fluid viscosity, aiding in the extraction of hydrocarbons.
Guar gum 200 mesh is used as a thickener in textile printing and sizing processes.

Guar gum 200 mesh helps control the viscosity of printing pastes and improves the adherence of dyes to fabrics.
Guar gum 200 mesh is used in the pharmaceutical industry as a binder in the formulation of tablets.
Guar gum 200 mesh provides cohesiveness to the tablet mass and aids in the controlled release of active ingredients.

Guar gum 200 mesh is used in cosmetics and personal care products, including shampoos, lotions, and creams, to enhance viscosity and provide a smooth texture.
In mining, Guar gum 200 mesh is used as a flocculant in the settling of solid particles in ore processing.
Guar gum 200 mesh helps improve the efficiency of solid-liquid separation processes.

Guar gum 200 mesh is used in the paper industry as a strength agent and to improve sheet formation.
Guar gum 200 mesh helps control the viscosity of paper pulp.
Guar gum 200 mesh is used in the explosives industry to improve the stability and rheological properties of explosive formulations.

Guar gum 200 mesh is utilized in the tobacco industry to enhance the bonding of tobacco particles in the production of cigarettes.
Guar gum 200 mesh is employed in textile dyeing and printing processes to improve the consistency and adhesion of colorants to fabrics.
In the formulation of detergents and cleaners, Guar gum 200 mesh is used to enhance the viscosity of liquid products, providing better stability and adherence to surfaces.

Guar gum 200 mesh is used in civil engineering applications, particularly in soil stabilization and erosion control.
Guar gum 200 mesh is used in water treatment processes as a flocculant to aid in the settling of suspended particles.
Guar gum 200 meshis added to various food products as a food additive to achieve specific textures, stability, and mouthfeel.

Guar gum 200 mesh is used in agriculture to improve water absorption in soil and as a binder in the production of agricultural pellets and granules.
Guar gum 200 mesh is also a key ingredient in some bulk-forming laxatives, helping to relieve constipation and some digestion ailments.
Guar gum 200 mesh is difficult for humans to digest, so acts as a filler and can slow the digestion of a meal (e.g. the rate of absorption of sugars by diabetics).

Guar gum 200 mesh may also increase basal metabolic rate (thermogenic).
Guar gum 200 mesh has been used in the food industry for thousands of years.
Guar gum 200 mesh is used in many liquid-solid systems, including ice cream, milk gels, and fruit-based water gels.

Guar gum 200 mesh is a water-soluble stabilizer, which can be used in a variety of applications.
Guar gum 200 mesh can be combined with other gums to produce a more effective stabilizer.
Guar gum 200 mesh can be used in ice cream to reduce the growth of ice crystals.

Guar gum 200 mesh powder is also used to thicken sauces and add to the texture of processed meat products.
Guar gum 200 mesh is also used as an emulsifier in many liquid-solid systems.
Guar gum 200 mesh is used in ice cream as a superior stabilizer.

Guar gum 200 mesh ensures desired texture by preventing the formation of coarse ice crystals, and it gives stability during freeze-thaw cycles.
Guar gum 200 mesh may be used in certain air fresheners and fragrance products to provide viscosity and enhance the stability of the formulations.
In some formulations for fire retardants, Guar gum 200 mesh is utilized to improve the adherence of the retardant to surfaces.

Guar gum 200 mesh is incorporated into some medical and dental gels, such as oral gels and topical gels, for its thickening and stabilizing properties.
Guar gum 200 mesh finds use in oil well drilling fluids as a thickening agent and fluid loss control additive.
Guar gum 200 mesh is used in the formulation of certain insecticides and pesticides to improve the adhesion of active ingredients to target surfaces.

Guar gum 200 mesh has been historically used in the photography industry to increase the viscosity of photographic emulsions.
Guar gum 200 mesh may be found in art and craft supplies, such as paints and adhesives, to provide viscosity and improve the consistency of formulations.
In biomedical research, Guar gum 200 mesh has been explored for its potential use in drug delivery systems and tissue engineering due to its biocompatible nature.

Guar gum 200 mesh is used in some hygiene products, including certain types of wet wipes, to enhance the viscosity of the liquid formulations.
Guar gum 200 mesh may be used in the formulation of some deodorants and antiperspirants to provide a smooth and stable texture.
Guar gum 200 mesh is utilized in the production of certain air freshener gels to control the release of fragrance and maintain the gel structure.

In the oil and gas industry, Guar gum 200 mesh is used in well stimulation processes to improve fluid viscosity and transport proppants into fractures.
Guar gum 200 mesh is sometimes used in the ceramics industry to improve the rheological properties of ceramic slurries.
Guar gum 200 mesh has been investigated for its potential use in bioremediation processes to aid in the removal of pollutants from contaminated environments.

Guar gum 200 mesh is used in a number of products, ranging from cheese spreads to gravies.
Guar gum 200 mesh is also used in dairy products, including ice cream and yogurt.
Guar gum 200 mesh can also be used in foods marketed as vegan or gluten-free.

Guar gum 200 mesh can be combined with other stabilizers to create a gel.
Guar gum 200 mesh powder is an important ingredient in ice cream.
Guar gum 200 mesh helps to create a smooth texture and enhances the perception of creaminess.

Guar gum 200 mesh is also used to make ice cream thicker.
Guar gum 200 mesh is used as a thickener and emulsifier in many foods.
Guar gum 200 mesh is widely used as a thickener in sauces, puddings, ice creams, and yogurts.

Guar gum 200 mesh also acts as a water-blocking additive.
Guar gum 200 mesh helps to inhibit the separation of ingredients, making it a good choice for high temperature, short-time processes.
Guar gum 200 mesh is also used in liquid marinades, ice creams, and soups.

Guar gum 200 mesh is also used as a fat replacer.
Guar gum 200 mesh is largely used as an additive in food products, but it also finds applications in the textile and pharmaceutical industries.
Guar gum 200 mesh is also used as a water-blocking agent in explosives.

Guar gum 200 mesh is also used in multi-phase formulations for hydraulic fracturing.
Guar gum 200 mesh is a galactomannan, commonly used in cosmetics, food products, and pharmaceutical formulations.
Guar gum 200 mesh has also been investigated in the preparation of sustained-release matrix tablets in the place of cellulose derivatives such as methylcellulose.

Safety Profile:
Guar gum 200 mesh is widely used in foods, and oral and topical pharmaceutical formulations.
Excessive consumption may cause gastrointestinal disturbance such as flatulence, diarrhea, or nausea.
Therapeutically, daily oral doses of up to 25 g of Guar gum 200 mesh have been administered to patients with diabetes mellitus.

Although it is generally regarded as a nontoxic and nonirritant material, the safety of Guar gum 200 mesh when used as an appetite suppressant has been questioned.
When consumed, the Guar gum 200 mesh swells in the stomach to promote a feeling of fullness.
However, Guar gum 200 mesh is claimed that premature swelling of guar gum tablets may occur and cause obstruction of, or damage to, the esophagus.

Consequently, appetite suppressants containing Guar gum 200 mesh in tablet form have been banned in the UK.
However, appetite suppressants containing microgranules of Guar gum 200 mesh are claimed to be safe.
The use of Guar gum 200 mesh for pharmaceutical purposes is unaffected by the ban.



GUAR GUM 5000 CPS

Guar gum 5000 CPS refers to Guar gum 5000 CPS that has a viscosity of 5000 centipoises (cps) when dissolved in a specified concentration of water.
Guar gum 5000 CPS itself is a natural polysaccharide derived from the seeds of the guar plant (Cyamopsis tetragonoloba).
Guar gum 5000 CPS is composed of long chains of galactomannan, a type of polysaccharide consisting of mannose and galactose units linked by glycosidic bonds.

CAS Number: 9000-30-0
EC Number: 232-536-8

Synonyms: Guaran gum, Guar flour, Guar bean gum, Cyamopsis gum, Cyamopsis tetragonoloba gum, Galactomannan, Galactomannose, JaGuar gum 5000 CPS, Cyamopsis tetragonolobus gum, Guaran gummi, Gomme de guar, Goma guar, Cyamopsis gummi, Cyamopsis tetragonolobus seed gum, Goma guar, Guaran seed gum, Guaran flour, Guaran gummi, Guaran endosperm gum, Guarane, Guarane flour, Guarane gum, Guarane seed gum, Guarane flour, Guarane gummi, Guarane endosperm gum, Guarane seed gum, Gomme guar, Gum guar



APPLICATIONS


Guar gum 5000 CPS is widely used in the food industry as a thickening agent in sauces, gravies, and soups.
Guar gum 5000 CPS is added to dairy products like yogurt and ice cream to improve texture and prevent ice crystal formation.

Guar gum 5000 CPS is utilized in bakery products to enhance dough consistency and increase moisture retention.
In gluten-free baking, Guar gum 5000 CPS acts as a binder and improves the texture of baked goods.

Guar gum 5000 CPS is used in beverages as a stabilizer and emulsifier to prevent ingredient separation.
Guar gum 5000 CPS is added to meat products such as sausages and burgers to improve binding and reduce fat content.

Guar gum 5000 CPS is used in canned pet foods to improve texture and palatability.
Guar gum 5000 CPS is employed in pharmaceutical formulations as a binder in tablets and a suspending agent in liquid medications.
Guar gum 5000 CPS is used in cosmetics and personal care products as a thickener and emulsifier in lotions, creams, and shampoos.

Guar gum 5000 CPS is added to toothpaste formulations to improve texture and enhance mouthfeel.
Guar gum 5000 CPS is used in textile printing as a thickening agent to improve print definition and color yield.

Guar gum 5000 CPS is employed in the paper industry as a wet-end additive to improve paper strength and formation.
Guar gum 5000 CPS is added to hydraulic fracturing fluids in the oil and gas industry as a viscosifier and fluid loss control agent.

Guar gum 5000 CPS is used in mining applications as a flocculant and depressant in mineral processing.
Guar gum 5000 CPS is employed in explosives formulations as a binding and gelling agent.

Guar gum 5000 CPS is added to household cleaning products as a thickener and stabilizer.
Guar gum 5000 CPS is used in water treatment processes as a flocculant to remove suspended particles and clarify water.
Guar gum 5000 CPS is employed in air fresheners and deodorizers to encapsulate and neutralize odors.

Guar gum 5000 CPS is used in textile sizing to improve the strength and printability of fabrics.
Guar gum 5000 CPS is added to plant-based meat substitutes to improve texture and binding properties.
Guar gum 5000 CPS is used in agricultural products such as pesticides and fertilizers as a binder and dispersing agent.

Guar gum 5000 CPS is added to ceramic glazes to improve suspension and adhesion.
Guar gum 5000 CPS is used in fire retardant materials to improve viscosity and prevent dripping.

Guar gum 5000 CPS is employed in paint and coating formulations to improve viscosity and flow properties.
Guar gum 5000 CPS is used in construction materials such as cement and mortar to improve workability and reduce water usage.

Guar gum 5000 CPS is added to dietary supplements and fiber products to promote digestive health and regulate bowel movements.
Guar gum 5000 CPS is used in the production of dietary fiber supplements to increase fiber content in the diet.

Guar gum 5000 CPS is employed in weight loss products and meal replacement shakes to promote satiety and reduce calorie intake.
Guar gum 5000 CPS is added to oral care products such as mouthwash and toothpaste as a thickening agent and binder.

Guar gum 5000 CPS is used in the production of gel capsules and softgels as a suspending agent for active ingredients.
Guar gum 5000 CPS is employed in the pharmaceutical industry as a stabilizer in suspensions and emulsions.

Guar gum 5000 CPS is used in ophthalmic formulations as a lubricant and viscosity enhancer in eye drops and ointments.
Guar gum 5000 CPS is added to veterinary medications and supplements for animals as a binder and flavor enhancer.

Guar gum 5000 CPS is used in the production of biodegradable films and coatings for food packaging.
Guar gum 5000 CPS is employed in the textile industry as a sizing agent to improve the strength and abrasion resistance of fabrics.
Guar gum 5000 CPS is added to ink formulations for printing and packaging to improve print quality and adhesion.

Guar gum 5000 CPS is used in the production of batteries as a thickener and binder for electrode materials.
Guar gum 5000 CPS is employed in the production of air fresheners and odor eliminators to encapsulate and neutralize odors.

Guar gum 5000 CPS is added to fire extinguishing foams as a thickening agent to improve foam stability and coverage.
Guar gum 5000 CPS is used in the production of dietary supplements for joint health to improve viscosity and lubrication.

Guar gum 5000 CPS is employed in the production of hair care products such as shampoos and conditioners as a thickener and emulsifier.
Guar gum 5000 CPS is added to pet care products such as grooming aids and dental chews as a binder and texture enhancer.
Guar gum 5000 CPS is used in the production of agricultural adjuvants to improve the performance and efficacy of pesticides and herbicides.

Guar gum 5000 CPS is employed in the production of rubber products such as tires and conveyor belts as a thickener and reinforcement agent.
Guar gum 5000 CPS is added to personal lubricants and intimate gels as a thickening agent and lubricant.

Guar gum 5000 CPS is used in the production of biodegradable plastics and packaging materials as a binder and film-forming agent.
Guar gum 5000 CPS is employed in the production of adhesive products such as tapes and labels as a thickener and tackifier.
Guar gum 5000 CPS is added to air fresheners and deodorizers for household and automotive use as a gelling agent and odor neutralizer.

Guar gum 5000 CPS is used in the production of soil stabilizers and erosion control products for landscaping and construction applications.
Guar gum 5000 CPS is employed in the production of dietary supplements for cardiovascular health to improve cholesterol levels and reduce blood sugar spikes.

Guar gum 5000 CPS exhibits pseudoplastic behavior, meaning its viscosity decreases under shear stress.
The molecular structure of Guar gum 5000 CPS consists of mannose and galactose units linked by glycosidic bonds.
Guar gum 5000 CPS is biodegradable and environmentally friendly.

It is resistant to degradation by enzymes and acids.
Guar gum 5000 CPS has a swelling capacity, absorbing water to form viscous solutions or gels.

Guar gum 5000 CPS is commonly used in the food industry as a thickener, stabilizer, and emulsifier.
Guar gum 5000 CPS is also used in pharmaceuticals, cosmetics, textiles, and other industrial applications.

Guar gum 5000 CPS improves the texture, mouthfeel, and shelf life of food products.
It enhances the stability and consistency of pharmaceutical formulations.

Guar gum 5000 CPS is often added to dairy products to prevent syneresis and improve creaminess.
In baking, Guar gum 5000 CPS improves dough consistency and helps retain moisture.
Guar gum 5000 CPS is an essential ingredient in gluten-free products as a binder and texturizer.
Guar gum 5000 CPS is used in the production of paper, textiles, and adhesives for its binding properties.

Guar gum 5000 CPS is classified as Generally Recognized as Safe (GRAS) by regulatory authorities.
Guar gum 5000 CPS is valued for its versatility, functionality, and natural origin in various industries.



DESCRIPTION


Guar gum 5000 CPS refers to Guar gum 5000 CPS that has a viscosity of 5000 centipoises (cps) when dissolved in a specified concentration of water.
Guar gum 5000 CPS itself is a natural polysaccharide derived from the seeds of the guar plant (Cyamopsis tetragonoloba).
Guar gum 5000 CPS is composed of long chains of galactomannan, a type of polysaccharide consisting of mannose and galactose units linked by glycosidic bonds.

The "5000 CPS" designation indicates the viscosity of the Guar gum 5000 CPS solution when measured in centipoises, which is a unit of viscosity.
CPS stands for "centipoises" and is commonly used to express the viscosity of liquids.

Guar gum 5000 CPS 5000 CPS is often used in various industries such as food, pharmaceuticals, cosmetics, and textiles for its thickening, stabilizing, and emulsifying properties.
The specific viscosity of 5000 cps makes it suitable for applications where a higher viscosity is desired, such as in the production of certain food products, pharmaceutical formulations, and industrial applications.

Guar gum 5000 CPS is a natural polysaccharide derived from the seeds of the guar plant (Cyamopsis tetragonoloba).
Guar gum 5000 CPS is a fine, white to yellowish powder with a neutral odor.
Guar gum 5000 CPS has a bland taste and is virtually odorless.

The texture of Guar gum 5000 CPS powder is smooth and free-flowing.
When hydrated, Guar gum 5000 CPS forms viscous solutions or gels.

Guar gum 5000 CPS has excellent thickening and stabilizing properties.
Guar gum 5000 CPS imparts a smooth and creamy texture to food products.
Due to its high viscosity, Guar gum 5000 CPS is used as a thickening agent in various applications.

Guar gum 5000 CPS is soluble in cold and hot water but insoluble in most organic solvents.
Guar gum 5000 CPS is compatible with a wide range of pH levels, making it versatile in different formulations.


PROPERTIES


Physical Properties:

Appearance: Fine, white to yellowish powder
Odor: Odorless or faint characteristic odor
Taste: Virtually tasteless
Solubility: Soluble in cold and hot water, insoluble in most organic solvents
Density: Approximately 0.8-1.2 g/cm³
Particle Size: Typically ranges from 100 to 300 mesh
pH: Neutral to slightly acidic (pH around 6-7 in aqueous solution)
Viscosity: Forms highly viscous solutions or gels when hydrated
Hygroscopicity: Absorbs water readily, forming viscous solutions or gels
Melting Point: Decomposes at high temperatures without melting
Boiling Point: Decomposes before boiling
Flammability: Non-flammable and non-combustible
Stability: Stable under normal storage conditions, but may degrade over time with exposure to heat, moisture, or high pH.



FIRST AID


Inhalation:

If inhalation of Guar gum 5000 CPS dust or particles occurs and respiratory irritation develops, remove the affected person to fresh air.
Allow the individual to rest in a well-ventilated area.
If breathing difficulties persist, seek medical attention immediately.


Skin Contact:

In case of skin contact with Guar gum 5000 CPS powder or solutions, promptly remove contaminated clothing and rinse the affected area with plenty of water.
Wash the skin thoroughly with mild soap and water to remove any residue.
If irritation, redness, or rash develops, seek medical advice.


Eye Contact:

If Guar gum 5000 CPS powder or solutions come into contact with the eyes, immediately flush the eyes with lukewarm water for at least 15 minutes, ensuring that eyelids are held open to facilitate thorough rinsing.
Seek immediate medical attention if irritation, pain, or redness persists.


Ingestion:

If Guar gum 5000 CPS is ingested accidentally and the individual is conscious, rinse the mouth thoroughly with water to remove any remaining substance.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek medical advice or assistance immediately, and provide relevant information such as the amount ingested and the individual's symptoms.


General First Aid:

If any symptoms persist or worsen after exposure to Guar gum 5000 CPS, seek medical attention promptly.
Provide first aid responders with Safety Data Sheets (SDS) or product information for proper assessment and treatment guidance.
Do not administer any medication or treatment without professional medical advice.
Keep the affected individual calm and reassured during first aid procedures.


Additional Information:

Guar gum 5000 CPS is generally considered low in toxicity, but individual sensitivity may vary.
Avoid contact with eyes, skin, and mucous membranes as much as possible to prevent irritation.
If Guar gum 5000 CPS is used in industrial settings, ensure that appropriate personal protective equipment (PPE) is worn to minimize exposure.
Follow all safety precautions and guidelines provided by manufacturers and regulatory agencies for safe handling and use of Guar gum 5000 CPS.
Store Guar gum 5000 CPS products securely in sealed containers and away from incompatible materials to prevent accidental exposure.
In case of emergency, contact local poison control centers or healthcare professionals for further assistance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate personal protective equipment (PPE) such as safety goggles, gloves, and protective clothing when handling Guar gum 5000 CPS to minimize skin and eye contact.
Use respiratory protection (e.g., dust mask) if working with Guar gum 5000 CPS powder to prevent inhalation of dust particles.

Ventilation:
Ensure adequate ventilation in the handling area to minimize exposure to airborne dust or vapors.
Use local exhaust ventilation systems or mechanical ventilation to remove airborne contaminants.

Handling Precautions:
Avoid generating dust when handling Guar gum 5000 CPS powder by using dust suppression techniques such as dampening or containment.
Use appropriate handling equipment (e.g., scoops, shovels) to minimize spills and dust generation.
Avoid eating, drinking, or smoking in areas where Guar gum 5000 CPS is handled to prevent accidental ingestion or inhalation.

Spill and Leak Procedures:
Clean up spills or leaks of Guar gum 5000 CPS promptly to prevent contamination and minimize the risk of slips and falls.
Use absorbent materials (e.g., vermiculite, sand) to contain and absorb spills, then dispose of according to local regulations.
Avoid washing Guar gum 5000 CPS residues directly into drains or waterways to prevent environmental contamination.

Fire and Explosion Hazards:
Guar gum 5000 CPS is non-flammable and non-combustible under normal conditions.
However, avoid exposure to high temperatures or sources of ignition as it may decompose and release hazardous gases.


Storage:

Storage Conditions:
Store Guar gum 5000 CPS in a cool, dry, well-ventilated area away from direct sunlight and heat sources.
Keep containers tightly closed when not in use to prevent contamination and moisture ingress.
Ensure storage areas are clean, organized, and free from potential sources of contamination.

Temperature Control:
Maintain storage temperature within the recommended range to prevent degradation or changes in properties.
Avoid exposure to extreme temperatures, as high temperatures can cause Guar gum 5000 CPS to degrade or lose functionality.

Container Compatibility:
Store Guar gum 5000 CPS in containers made of compatible materials such as high-density polyethylene (HDPE), polypropylene (PP), or glass.
Ensure containers are labeled with relevant hazard warnings and handling instructions for easy identification.

Protection from Contamination:
Prevent cross-contamination by storing Guar gum 5000 CPS away from incompatible materials such as strong acids, alkalis, or oxidizing agents.
Keep storage areas clean and free from dust, dirt, or other foreign particles that may contaminate the product.

Handling Precautions:
Handle containers with care to prevent damage or leakage.
Do not stack heavy objects on top of Guar gum 5000 CPS containers to avoid deformation or breakage.
Use appropriate material handling equipment (e.g., pallets, forklifts) to transport and store Guar gum 5000 CPS safely.

Security Measures:
Secure storage areas to prevent unauthorized access or tampering with Guar gum 5000 CPS containers.
Limit access to authorized personnel trained in handling and storage procedures.

GUAR GUM FOOD GRADE
Guar gum food grade occurs as an odorless or nearly odorless, white to yellowish-white powder with a bland taste.
Guar gum food grade, often referred to as guaran, is a food-grade substance derived from guar beans, which are the seeds of the guar plant (Cyamopsis tetragonoloba).
Guar gum, like locust bean gum, is a galactomannan derived from the seed of a leguminous plant.

CAS Number: 9000-30-0
Molecular Formula: C10H14N5Na2O12P3
Molecular Weight: 535.145283
EINECS Number: 232-536-8

Guar gum food grade, also called guaran, is a galactomannan polysaccharide extracted from guar beans that has thickening and stabilizing properties useful in food, feed, and industrial applications.
The guar seeds are mechanically dehusked, hydrated, milled and screened according to application.
Guar gum food grade is typically produced as a free-flowing, off-white powder.

Guar gum food grade is white to light yellowish.
Guar gum food grade form viscous liquid after dispersing in hot or cold water.
The viscosity of 1% aqueous solution is about 4~5Pa which is the highest viscosity in natural rubber.

After adding small amount of sodium tetraborate Guar gum food grade changes to gel.
After dispersing in cold water for about 2h Guar gum food grade shows strong viscosity and the viscosity gradually increases reached the highest point after 24h.
Guar gum food grade is viscosity is 5 to 8 times than that of starch and quickly reaches the highest point under heat.

The aqueous solution is neutral.The viscosity is highest with pH between 6 and 8 and substantially decreases when pH is above.
And viscosity decreases sharply along with pH value dropping when pH value is 6.0 to 3.5. The viscosity below 3.5 increases again.
The source of Guar gum food grade, Cyamopsis tetragonolobus, is widely grown in Pakistan and India as cattle feed, and was introduced to the United States as a cover crop in 1903.

Guar gum food grade was not until 1953, however, that guar gum was produced on a commercial scale, primarily as a replacement for locus bean gum in the paper, textile and food industries.
The most important property of guar is the ability to hydrate rapidly in cold water to attain a very high viscosity.
In addition to the food industry, Guar gum food grade is used in the mining, paper, textile, ceramic, paint, cosmetic, pharmaceutical, explosive, and other industries.

Guar gum food grade is a hardy and drought-resistant plant which grows three to six feet high with vertical stalks.
Guar gum food grades, which grow in clusters along the vertical stems, are about six inches long and contain 6 to 9 seeds, which are considerably smaller than locus bean seeds.
As in the case of locust bean Guar gum food grade, the endosperm, which comprises 35-42%.

Guar gum food grade is a white to yellowish white powder and is nearly odorless.
Fine finished Guar gum food grade Powder is available in different viscosities and granulometries depending on the desired viscosity development and applications.
Guar gum food grade is a natural high molecular weight hydrocolloidal polysaccharide composed of galactan and mannan units combined through glycosidic linkages, which may be described chemically as galactomannan.

Guar gum food grade is a cold water soluble polysaccharide, consisting of mannose and galactose units.
This ability to hydrate without heating makes Guar gum food grade very useful in many industrial and food applications.
Dissolved in cold or hot water, Guar gum food grade forms a slime of high viscosity.

Guar gum food grade's viscosity is a function of temperature, time, and concentration.
Solutions with different Guar gum food grade concentrations can be used as emulsifiers and stabilizers because they prevent oil droplets from coalescing.
Guar gum food grade is also used as suspension stabilizer.

Guar gum food grade is derived from the ground endosperm of guar beans.
Guar gum food grade plant, Cyanmopsis tetragonoloba, is mainly grown in India, but also Pakistan, the US, Australia and Africa.
Guar gum food grade is obtained after the beans are de-husked, milled and sieved.

Guar gum food grade is sold as an off-white powder and forms a gel when dissolved in water (hydrocolloid) and mixed with borax or calcium.
Guar gum food grade is an effective thickener as only a small quantity (1% concentration) is required to form a viscous solution, although its viscosity reduces at lower temperatures or when vigorously shaken.
Guar gum food grade powder is available in high and medium visocity grades. Guar gum also acts as a stabiliser (it prevents solid particles in a liquid from settling) and an emulsifier (it prevents oil droplets from coalescing).

Guar gum food grade remains stable in solution over a pH range of 5-7.
Guar gum food grade may have synergistic effects with Xanthan gum, Locust Bean gum and Sodium Alginate.
Guar gum food grade powder grades categorized in two are food grade and industrial grade powder.

The food grade is for processes such as baking, freezing, enhancing textures, beverages, canning, meat products, cheese production and much more.
Meanwhile, the industrial grade is for processes such as explosive making, ore extraction, mining, textile printing, among others.
Guar gum food grade is well known for its ability to thicken and stabilize food products, but it may also provide some health benefits.

Studies indicate that Guar gum food grade could be beneficial for a few specific areas of health, including digestion, blood sugar and cholesterol levels, and weight maintenance.
Guar gum food grade is a Polysaccharide produced from the endosperm contained in the seeds (beans) of the Guar plant (Endosperm is the white fleshy part of the guar bean which is used as nutrition when the plant begins to grow).
The beans are de-husked and then the endosperm extracted; its then ground to a fine powder to produce guar gum.

Guar gum food grade functions as an emulsion stabiliser, a thickener in liquids, and a binding agent.
In baking, Guar gum food grade improves dough volume, texture and shelf life, whilst preventing moisture in pastry fillings from making the pastry soggy.
Guar gum food grade is often used in gluten free flour to help the dough rise.

In dairy products, Guar gum food grade thickens milk, yogurt and cottage cheese, and helps maintain the texture and homogeneity of ice creams and other frozen desserts, whilst retarding the growth of ice crystals.
Guar gum food grade improves the appearance and stability of condiments such as ketchups and barbecue sauces, as well as relishes, salad dressings and pastes.
In is used as a thickener and stabiliser in canned soup and fish in sauces, as well as in dry soups and instant oatmeal.

Guar gum food grade acts as a binder in meat.
Guar gum food grade is also a good source of dietary fibre (80% on a dry weight basis) and an additive in animal food, including pet food.
Guar gum food grade is the endosperm of the seed of the Indian cluster bean, Cyamopsis tetragonolobus.

Guar gum food grade has been grown for several thousand years in India and Pakistan as a vegetable and a forage crop.
Guar gum food grade is a hardy and drought-resistant plant, which grows 1 to 2 m high with vertical stalks and resembles the soybean plant in general appearance.
Guar gum food grade pods, which grow in clusters along the vertical stems, are about 30 cm long and contain six to nine seeds, which are considerably smaller than locust bean seeds Guar gum is odorless.

As in the case of locust bean Guar gum food grade, the endosperm, which comprises 35 to 42% of the seed, is the source of the gum Typically, guar gum is around 80% of the endosperm of the guar seed.
As the endosperm is about 40% of the seed, Guar gum food grade is roughly 30% of the guar plant seed.
Guar gum food grade is harvested before the frst rain following the frst frost to obtain maximum yield and purity (Burdock, 1997).

Guar gum food grade as a gum obtained from the ground endosperms of Cyamopsis tetragonolobus (L.) Taub.
Guar gum food grade consists chiefly of a high-molecular-weight hydrocolloidal polysaccharide, composed of galactan and mannan units combined through glycoside linkages, which may be described chemically as a galactomannan.
The main components are polysaccharides composed of Dgalactose and D-mannose in molecular ratios of 1 : 1.4 to 1 : 2.

The molecule consists of a linear chain of b-(1!4)-glycosidically linked manno-pyranoses and single a-(1→6)-glycosidically linked galactopyranoses.
Guar gum food grade is yish-white free-flowing powder.
Completely soluble in hot or cold water.

Practically insoluble in oils, greases, hydrocarbons, ketones, esters.
Water solutions are tasteless, odorless, nontoxic.
Guar gum food grade reduces the friction drag of water on metals.

Guar gum food grade is a white to yellowish-white powder.
Guar gum food grade is dispersible in either hot or cold water, forming a solution having a pH between 5.4 and 7.0 that may be converted to gel by the addition of a small amount of sodium borate.
Guar gum food grade bean is principally grown in India, Pakistan, the United States, Australia and Africa.

India is the largest producer, accounting for nearly 80% of the world production.
In India, Rajasthan, Gujarat, and Haryana are the main producing regions.
The US has produced 4,600 to 14,000 tonnes of guar over the last 5 years.

Texas acreage since 1999 has fluctuated from about 7,000 to 50,000 acres.
The world production for Guar gum food grade and its derivatives is about 1.0 million tonnes.
Non-food guar gum accounts for about 40% of the total demand.

Food grade Guar Gum Powder is a natural, plant-based, soluble fiber that is derived from the seed of the guar plant.
Guar gum food grade is commonly used as a thickening, stabilizing, and emulsifying agent in a wide range of food and beverage applications.
Some of the popular food products that contain guar gum powder include ice cream, baked goods, sauces, dressings, soups, and beverages.

The food grade guar gum powder is known for its ability to enhance the texture, viscosity, and shelf life of food products.
Guar gum food grade is also gluten-free, non-GMO, and vegan, making it an ideal ingredient for various dietary requirements.
Guar gum food grade is a ether-alcohol derivative, the ether being relatively unreactive.

Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents.
They react with oxoacids and carboxylic acids to form esters plus water.
Oxidizing agents convert alcohols to aldehydes or ketones.

Alcohols exhibit both weak acid and weak base behavior.
They may initiate the polymerization of isocyanates and epoxides.
Guar gum food grade is an exo-polysaccharide composed of the sugars galactose and mannose.

The backbone is a linear chain of β 1,4-linked mannose residues to which galactose residues are 1,6-linked at every second mannose, forming short side-branches.
Guar gum food grade has the ability to withstand temperatures of 80 °C (176 °F) for five minutes.
Guar gum food grade is more soluble than locust bean gum due to its extra galactose branch points.

Unlike locust bean Guar gum food grade, it is not self-gelling.
Either borax or calcium can cross-link Guar gum food grade, causing it to gel.
In water, Guar gum food grade is nonionic and hydrocolloidal.

Guar gum food grade is not affected by ionic strength or pH, but will degrade at extreme pH and temperature (e.g. pH 3 at 50 °C).
Guar gum food grade remains stable in solution over pH range 5–7.
Strong acids cause hydrolysis and loss of viscosity and alkalies in strong concentration also tend to reduce viscosity.

Guar gum food grade is insoluble in most hydrocarbon solvents.
The viscosity attained is dependent on time, temperature, concentration, pH, rate of agitation and particle size of the powdered gum used.
The lower the temperature, the lower the rate at which viscosity increases, and the lower the final viscosity.

Above 80°, the final viscosity is slightly reduced.
Finer guar powders swell more rapidly than larger particle size coarse powdered gum.
Guar gum food grade shows a clear low shear plateau on the flow curve and is strongly shear-thinning.

The rheology of Guar gum food grade is typical for a random coil polymer.
Guar gum food grade does not show the very high low shear plateau viscosities seen with more rigid polymer chains such as xanthan gum.
Guar gum food grade is very thixotropic above 1% concentration, but below 0.3%, the thixotropy is slight.

Guar gum food grade shows viscosity synergy with xanthan gum.
Guar gum food grade and micellar casein mixtures can be slightly thixotropic if a biphase system forms.
Guar gum food grade is a naturally occurring polysaccharide.

Guar gum food grade contains galactose and mannan units.
Guar gum food grade is widely used in various industries such as food, personal care, and pharmaceuticals.
Guar gum food grade has an average molecular weight of 220 kDa.

Guar gum food grade is composed of about 80% guaran.
Guar gum food grade is commonly used in pharmaceuticals and cosmetics as a thickening and emulsifier.
Guar gum food grade is a good source of soluble dietary fiber.

Guar gum food grade is useful in maintaining intestinal function and cleansing the digestive system.
Guar gum food grade is also useful in treating diabetes and obesity.
Guar gum food grade has high water-holding capacity in hot water.

Guar gum food grade solutions are stable in a wide pH range.
Guar gum food grade is also used as a suspension stabilizer and gelling agent.
Guar gum food grade is also used in cosmetics, beverages, and fracking industries.

Guar gum food grade is an odorless polysaccharide.
Guar gum food grade is used in food industry, cosmetic industry, and pharmaceutical industry as a thickening agent, emulsifier, and gelling agent.
Guar gum food grade is one of the highest molecular weight polymers.

Guar gum food grade is also used in water phase control in various industries.
Guar gum food grade is also used as a laxative, foam stabilizer, and film-forming agent.
Guar gum food grade is used to treat diarrhea.

Guar gum food grade is a natural thickener and emulsifier with superior thickening and stabilizing properties.
Guar gum food grade is found in a wide variety of cosmetics and food products.
Guar gum food grade is widely used in shaving creams, lotions, deodorants, and toothpastes.

Guar gum food grade is also used in the paper, pharmaceutical, and oil well drilling industries.
Guar gum food grade powder in cosmetics is an economical option.
Guar gum food grade is produced from high quality ingredients, and it is guaranteed for non-allergic properties.

Guar gum food grade is ideal for use in emulsified systems, which helps to improve the shelf life of skin care products.
Guar gum food grade also helps to prevent water loss and minimizes syneresis.
Guar gum food grade is the leading producer of guar gum powder in the United States.

Guar gum food grade powder is completely safe to use, and it has been approved by the Food and Drug Administration.
Guar gum food grade can be used in an aqueous solution without heating, and it will also suspend solids.
Guar gum food grade powder can also be used to adjust the viscosity of aqueous solutions.

Guar gum food grade also minimizes friction from static charges, which helps to avoid separation of liquid from gel.
Guar gum food grade is extracted from guar beans, which are primarily grown in India, Pakistan, the United States, and several other countries.
Guar gum food grade plant is an annual legume.

Guar gum food grade is a polysaccharide composed of galactose and mannose units.
Guar gum food grade belongs to the family of galactomannans.
The molecular structure of Guar gum food grade imparts its thickening and stabilizing properties.

Guar gum food grade is valued for its ability to hydrate and form viscous solutions.
Guar gum food grade is highly effective as a thickener, stabilizer, and emulsifier in food formulations.
One of the primary uses of Guar gum food grade is as a thickening agent in various food products.

Guar gum food grade is particularly effective in increasing the viscosity of liquids and improving the texture of certain foods.
Guar gum food grade helps stabilize and emulsify certain food products, preventing the separation of ingredients and enhancing the overall stability of formulations.
Guar gum food grade is often used to improve the texture and mouthfeel of food products, providing a smooth and creamy consistency in items such as ice cream and dairy-based desserts.

Guar gum food grade is gluten-free, making it a valuable ingredient in gluten-free and low-gluten products as a substitute for traditional thickeners and stabilizers.
Guar gum food grade is used in the production of bread, cakes, and other baked goods to improve dough consistency, increase water retention, and enhance shelf life.
Guar gum food grade is commonly used in the production of dairy products, such as yogurt and ice cream, to provide stability, prevent ice crystal formation, and improve texture.

Guar gum food grade is employed in the formulation of sauces and dressings to enhance viscosity, stability, and overall product quality.
Guar gum food grade is used in certain beverages, including fruit juices and fruit-flavored drinks, to improve mouthfeel and prevent settling of particulate matter.
Guar gum food grade is used in the pet food industry to achieve desired textures and improve the palatability of pet food products.

Guar gum food grade is utilized in canned and processed foods to enhance the stability of suspensions and emulsions, preventing separation of ingredients.
Due to its ability to absorb water and create a feeling of fullness, Guar gum food grade is sometimes used in weight control products and high-fiber foods.

Melting point: >220°C (dec.)
alpha: D25 +53° (1N NaOH)
FEMA: 2537 | GUAR GUM (CYAMOPSIS TETRAGONOLOBUS (L.))
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: It yields a mucilage of variable viscosity when dissolved in water, practically insoluble in ethanol (96 per cent).
form: Free Flowing Powder
color: Yellow-white
Odor: Odorless
Viscosity: 350 to 700 mPa-s(1 %, H2O, 20 ℃, calcd.on dried substance)
Merck: 13,4588 / 13,4587
Stability: Stable. Combustible. A mixture of air and finely-divided powder is potentially explosive. Incompatible with strong oxidizing agents.

Guar gum food grade molecules have a tendency to aggregate during the hydraulic fracturing process, mainly due to intermolecular hydrogen bonding.
Guar gum food grade is obtained from the ground endosperm of the guar plant, Cyamopsis tetragonolobus (L.) Taub. (Fam. Leguminosae), which is grown in India, Pakistan, and the semiarid southwestern region of the USA.
The seed hull can be removed by grinding, after soaking in sulfuric acid or water, or by charring.

The embryo (germ) is removed by differential grinding, since each component possesses a different hardness.
The separated endosperm, containing 80% galactomannan is then ground to different particle sizes depending upon final application.
Guar gum food grade is a thickening agent in foods and medicines for humans and animals.

Because it is gluten-free, Guar gum food grade is used as an additive to replace wheat flour in baked goods.
Guar gum food grade has been shown to reduce serum cholesterol and lower blood glucose levels.
Guar gum food grade is also economical because it has almost eight times the water-thickening ability of other agents (e.g. cornstarch) and only a small quantity is needed for producing sufficient viscosity.

Guar gum food grade's effects on viscosity, its high ability to flow, or deform, gives it favorable rheological properties.
Guar gum food grade forms breakable gels when cross-linked with boron.
Guar gum food grade is used in various multi-phase formulations for hydraulic fracturing, in some as an emulsifier because it helps prevent oil droplets from coalescing, and in others as a stabilizer to help prevent solid particles from settling and/or separating.

Guar gum food grade retards ice crystal growth by slowing mass transfer across the solid/liquid interface.
Guar gum food grade shows good stability during freeze-thaw cycles.
Thus, Guar gum food grade is used in egg-free ice cream.

Guar gum food grade has synergistic effects with locust bean gum and sodium alginate.
May be synergistic with xanthan: together with xanthan gum, it produces a thicker product (0.5% guar gum / 0.35% xanthan gum), which is used in applications such as soups, which do not require clear results.
Guar gum food grade is a hydrocolloid, hence is useful for making thick pastes without forming a gel, and for keeping water bound in a sauce or emulsion.

Guar gum food grade can be used for thickening cold and hot liquids, to make hot gels, light foams and as an emulsion stabilizer.
Guar gum food grade can be used for cottage cheeses, curds, yoghurt, sauces, soups and frozen desserts.
Guar gum food grade is also a good source of fiber with 80% soluble dietary fiber on a dry weight basis.

Using food grade Guar gum food grade powder in ice cream stabilization is increasing as the market for organic ice cream grows.
Guar gum food grade powder is an organic stabilizer, which can thicken and improve the texture and body of ice cream.
Guar gum food grade also improves the heat shock resistance of the product and helps maintain the creamy texture of reduced calorie dairy products.

Guar gum food grade is extracted from the seeds of the guar plant.
Guar gum food grades are preferred as thickeners for enhanced oil recovery (EOR).
Guar gum food grade and its derivatives account for most of the gelled fracturing fluids.

Guar gum food grade is more water-soluble than other gums, and it is also a better emulsifier, because it has more galactose branch points.
Guar gum food grade shows high low-shear viscosity, but it is strongly shear-thinning.
Being non-ionic, Guar gum food grade is not affected by ionic strength or pH but will degrade at low pH at moderate temperature (pH 3 at 50 °C).

Guar gum food grade's derivatives demonstrate stability in high temperature and pH environments.
Guar gum food grade use allows for achieving exceptionally high viscosities, which improves the ability of the fracturing liquid to transport proppant.
Guar gum food grade hydrates fairly rapidly in cold water to give highly viscous pseudoplastic solutions of, generally, greater low-shear viscosity than other hydrocolloids.

The colloidal solids present in guar make fluids more efficient by creating less filter cake.
Proppant pack conductivity is maintained by utilizing a fluid that has excellent fluid loss control, such as the colloidal solids present in Guar gum food grade.
Guar gum food grade has up to eight times the thickening power of starch.

Derivatization of guar gum leads to subtle changes in properties, such as decreased hydrogen bonding, increased solubility in water-alcohol mixture, and improved electrolyte compatibility.
These changes in properties result in increased use in different fields, like textile printing, explosives, and oil-water fracturing applications.
Guar gum food grade is compatible with most other plant hydrocolloids such as tragacanth.

Guar gum food grade is incompatible with acetone, ethanol (95%), tannins, strong acids, and alkalis.
Borate ions, if present in the dispersing water, will prevent the hydration of Guar gum food grade.
However, the addition of borate ions to hydrated Guar gum food grade produces cohesive structural gels and further hydration is then prevented.

The gel formed can be liquefied by reducing the pH to below 7, or by heating.
Guar gum food grade may reduce the absorption of penicillin V from some formulations by a quarter.
Guar gum food grade Powder is a natural, high molecular weight polymer derived from the seed of the guar plant.

Guar gum food grade is commonly used as a thickener, stabilizer, and binder in various industrial applications.
Unlike food grade Guar gum food grade powder, industrial grade guar gum powder is not intended for human consumption and is typically used in non-food applications.
Guar gum food grade is used in the meat industry to improve the texture, water retention, and stability of processed meat products such as sausages and luncheon meats.

In gluten-free baking, Guar gum food grade serves as a common additive to mimic the viscoelastic properties of gluten.
Guar gum food grade helps provide structure and improve the texture of gluten-free bread, cakes, and pastries.
Guar gum food grade is employed in the production of cereal bars and snack bars to enhance binding, texture, and overall product stability.

Guar gum food grade is used in soups and gravies as a thickening agent to achieve the desired consistency and improve mouthfeel.
Guar gum food grade is utilized in canned soups and ready-to-eat meals to maintain the stability of suspensions and prevent settling during storage.
Guar gum food grade is sometimes used in the formulation of dietary supplements, particularly those designed to provide fiber content and promote a feeling of fullness.

In dairy alternatives such as plant-based milk substitutes (e.g., almond milk, soy milk), Guar gum food grade may be used to improve texture and prevent ingredient separation.
Guar gum food grade is employed in the cheese industry to improve the texture and moisture retention of certain cheese products, including processed cheeses.
In vegetarian and vegan recipes, Guar gum food grade can be used as an egg replacer to provide binding and texture in baked goods.

Guar gum food grade is used in fruit fillings, jams, and jellies to enhance viscosity, improve texture, and prevent syneresis (liquid separation).
Guar gum food grade is used in the production of certain baby foods to provide viscosity and stability while ensuring ease of consumption.
Guar gum food grade is added to instant foods such as instant puddings, instant soups, and instant dessert mixes to achieve rapid thickening upon rehydration.

Guar gum food grade is employed in salad dressings to improve the emulsion stability and prevent separation of oil and water phases.
Guar gum food grade may be used in certain honey and syrup formulations to enhance viscosity and prevent crystallization.

Guar gum food grade is used in the production of nutritional and energy bars to provide texture, binding, and stability to the bars.
Guar gum food grade is sometimes used in processed seafood products, such as surimi-based products, to improve texture and water retention.

Uses:
Guar gum food grade is used in a number of products, ranging from cheese spreads to gravies.
Guar gum food grade is also used in dairy products, including ice cream and yogurt.
Guar gum food grade can also be used in foods marketed as vegan or gluten-free.

Guar gum food grade can be combined with other stabilizers to create a gel.
Guar gum food grade powder is an important ingredient in ice cream.
Guar gum food grade helps to create a smooth texture and enhances the perception of creaminess.

Guar gum food grade is also used to make ice cream thicker.
Guar gum food grade is used as a thickener and emulsifier in many foods.
Guar gum food grade is widely used as a thickener in sauces, puddings, ice creams, and yogurts.

Guar gum food grade also acts as a water-blocking additive.
Guar gum food grade helps to inhibit the separation of ingredients, making it a good choice for high temperature, short-time processes.
Guar gum food grade is also used in liquid marinades, ice creams, and soups.

Guar gum food grade is also used as a fat replacer.
Guar gum food grade is largely used as an additive in food products, but it also finds applications in the textile and pharmaceutical industries.
Guar gum food grade is also used as a water-blocking agent in explosives.

Guar gum food grade is also used in multi-phase formulations for hydraulic fracturing.
Guar gum food grade is a galactomannan, commonly used in cosmetics, food products, and pharmaceutical formulations.
Guar gum food grade has also been investigated in the preparation of sustained-release matrix tablets in the place of cellulose derivatives such as methylcellulose.

In pharmaceuticals, Guar gum food grade is used in solid-dosage forms as a binder and disintegrant; in oral and topical products as a suspending, thickening, and stabilizing agent; and also as a controlled-release carrier.
Guar gum food grade has also been examined for use in colonic drug delivery.
Guar gum food grade-based three-layer matrix tablets have been used experimentally in oral controlled-release formulations.

Therapeutically, Guar gum food grade has been used as part of the diet of patients with diabetes mellitus.
Guar gum food grade has also been used as an appetite suppressant, although its use for this purpose, in tablet form, is now banned in the UK.
Guar gum food grade is also used in ice cream stabilizers and cosmetics.

Guar gum food grade has a coating action on the skin that allows for moisture retention.
Guar gum food grade often used as a thickener and emulsifier in cosmetic formulations, guar gum is a polysaccharide found in the seeds of the guar plant.
Guar gum food grade is the nutrient material required by the developing plant embryo during germination.

When the endosperm, once separated from the hull and embryo, is ground to a powder form, it is marketed as Guar gum food grade.
Guar gum food grade is obtained from the seed kernel of the plant cyamopsis tetragonoloba.
Guar gum food grade has a mannose:galactose ratio of approximately 2:1.

Guar gum food grade is dispersible in cold water to form viscous sols which upon heating will develop additional viscosity.
A 1% solution has a viscosity range of 2,000–3,500 cp at 25°c.
Guar gum food grade is a versatile thickener and stabilizer used in ice cream, baked goods, sauces, and beverages at use levels ranging from 0.1 to 1.0%.

Guar gum food grade is scientifically termed guaran.
In paper sizing; as a protective colloid, stabilizer, thickening and film forming agent for cheese, salad dressings, ice cream, soups; as a binding and disintegrating agent in tablet formulations; in pharmaceutical jelly formulations; in suspensions, emulsions, lotions, creams, toothpastes; in the mining industry as a flocculant, as a filtering agent; in water treatment as a coagulant aid.
Guar gum food grade is used food additives, emulsifying stabilizer, thickener and gelling agent.

Guar gum food grade is used as binder or disintegrator in tablets.
Guar gum food grade is also a key ingredient in some bulk-forming laxatives, helping to relieve constipation and some digestion ailments.
Guar gum food grade is difficult for humans to digest, so acts as a filler and can slow the digestion of a meal (e.g. the rate of absorption of sugars by diabetics).

Guar gum food grade may also increase basal metabolic rate (thermogenic).
Guar gum food grade has been used in the food industry for thousands of years.
Guar gum food grade is used in many liquid-solid systems, including ice cream, milk gels, and fruit-based water gels.

Guar gum food grade is a water-soluble stabilizer, which can be used in a variety of applications.
Guar gum food grade can be combined with other gums to produce a more effective stabilizer.
Guar gum food grade can be used in ice cream to reduce the growth of ice crystals.

Guar gum food grade powder is also used to thicken sauces and add to the texture of processed meat products.
Guar gum food grade is also used as an emulsifier in many liquid-solid systems.
Guar gum food grade is used in ice cream as a superior stabilizer.

Guar gum food grade ensures desired texture by preventing the formation of coarse ice crystals, and it gives stability during freeze-thaw cycles.
Guar gum food grade may be used in certain air fresheners and fragrance products to provide viscosity and enhance the stability of the formulations.
In some formulations for fire retardants, Guar gum food grade is utilized to improve the adherence of the retardant to surfaces.

Guar gum food grade is incorporated into some medical and dental gels, such as oral gels and topical gels, for its thickening and stabilizing properties.
Guar gum food grade finds use in oil well drilling fluids as a thickening agent and fluid loss control additive.
Guar gum food grade is used in the formulation of certain insecticides and pesticides to improve the adhesion of active ingredients to target surfaces.

Guar gum food grade has been historically used in the photography industry to increase the viscosity of photographic emulsions.
Guar gum food grade may be found in art and craft supplies, such as paints and adhesives, to provide viscosity and improve the consistency of formulations.
In biomedical research, Guar gum food grade has been explored for its potential use in drug delivery systems and tissue engineering due to its biocompatible nature.

Guar gum food grade is used in some hygiene products, including certain types of wet wipes, to enhance the viscosity of the liquid formulations.
Guar gum food grade may be used in the formulation of some deodorants and antiperspirants to provide a smooth and stable texture.
Guar gum food grade is utilized in the production of certain air freshener gels to control the release of fragrance and maintain the gel structure.

In the oil and gas industry, Guar gum food grade is used in well stimulation processes to improve fluid viscosity and transport proppants into fractures.
Guar gum food grade is sometimes used in the ceramics industry to improve the rheological properties of ceramic slurries.
Guar gum food grade has been investigated for its potential use in bioremediation processes to aid in the removal of pollutants from contaminated environments.

Guar gum food grade can be used in inkjet printing inks to improve the viscosity and stability of the ink formulations.
Guar gum food grade can be used for cake making, producing gluten free food, bread making, ice-cream making and a gluten free thickener.
Guar gum food grade is used during the preparation of lotions and creams.

Guar gum food grade is often used by pharmaceutical companies to help bind tablets.
Guar gum food grade has been linked to a reduction in serum cholesterol having a positive effect on blood glucose.
Guar gum food grade is used as a binder in the pharmaceutical industry for tablets production.

Guar gum food grade is a thickening agent in textile printing, sizing, and finishing.
In the mining industry, Guar gum food grade is a froth or coagulation agent in ore processing as it is regarded as eco-friendly.
Guar gum food grade a mineral depressant especially in talc, calcite, and lead mining, also it is vital in copper-lead separation.

Guar gum food grade is used in water treatment and recycling, that is as Flocculation agent.
In addition, Guar gum food grade is used in the petroleum industry especially in drilling mud and fracturing fluids.
Guar gum food grade is a thickener in slurry-based explosives.

In the cosmetics industry, Guar gum food grade is a mixture stabilizer and surfactant.
Guar gum food grade is commonly used as a thickening agent in various food products such as sauces, dressings, soups, and gravies.
Guar gum food grade imparts viscosity and improves the texture of these formulations.

Guar gum food grade helps stabilize and emulsify certain food products, preventing the separation of ingredients in items like salad dressings and ice creams.
In gluten-free baking, Guar gum food grade is used as a binder and thickener to provide structure and improve the texture of baked goods.
Guar gum food grade is employed in hydraulic fracturing (fracking) fluids in the oil and gas industry.

Guar gum food grade helps to carry proppants into fractures and enhances fluid viscosity, aiding in the extraction of hydrocarbons.
Guar gum food grade is used as a thickener in textile printing and sizing processes.
Guar gum food grade helps control the viscosity of printing pastes and improves the adherence of dyes to fabrics.

Guar gum food grade is used in the pharmaceutical industry as a binder in the formulation of tablets.
Guar gum food grade provides cohesiveness to the tablet mass and aids in the controlled release of active ingredients.
Guar gum food grade is used in cosmetics and personal care products, including shampoos, lotions, and creams, to enhance viscosity and provide a smooth texture.

In mining, Guar gum food grade is used as a flocculant in the settling of solid particles in ore processing.
Guar gum food grade helps improve the efficiency of solid-liquid separation processes.
Guar gum food grade is used in the paper industry as a strength agent and to improve sheet formation.

Guar gum food grade helps control the viscosity of paper pulp.
Guar gum food grade is used in the explosives industry to improve the stability and rheological properties of explosive formulations.
Guar gum food grade is utilized in the tobacco industry to enhance the bonding of tobacco particles in the production of cigarettes.

Guar gum food grade is employed in textile dyeing and printing processes to improve the consistency and adhesion of colorants to fabrics.
In the formulation of detergents and cleaners, Guar gum food grade is used to enhance the viscosity of liquid products, providing better stability and adherence to surfaces.
Guar gum food grade is used in civil engineering applications, particularly in soil stabilization and erosion control.

Guar gum food grade is used in water treatment processes as a flocculant to aid in the settling of suspended particles.
Guar gum food gradeis added to various food products as a food additive to achieve specific textures, stability, and mouthfeel.
Guar gum food grade is used in agriculture to improve water absorption in soil and as a binder in the production of agricultural pellets and granules.

Safety:
Guar gum food grade is widely used in foods, and oral and topical pharmaceutical formulations.
Excessive consumption may cause gastrointestinal disturbance such as flatulence, diarrhea, or nausea.
Therapeutically, daily oral doses of up to 25 g of Guar gum food grade have been administered to patients with diabetes mellitus.

Although it is generally regarded as a nontoxic and nonirritant material, the safety of Guar gum food grade when used as an appetite suppressant has been questioned.
When consumed, the Guar gum food grade swells in the stomach to promote a feeling of fullness.
However, Guar gum food grade is claimed that premature swelling of guar gum tablets may occur and cause obstruction of, or damage to, the esophagus.

Consequently, appetite suppressants containing Guar gum food grade in tablet form have been banned in the UK.
However, appetite suppressants containing microgranules of Guar gum food grade are claimed to be safe.
The use of Guar gum food grade for pharmaceutical purposes is unaffected by the ban.

Storage:
Aqueous Guar gum food grade dispersions have a buffering action and are stable at pH 4.0–10.5.
However, prolonged heating reduces the viscosity of dispersions.

The bacteriological stability of Guar gum food grade dispersions may be improved by the addition of a mixture of 0.15% methylparaben and 0.02% propylparaben as a preservative.
Guar gum food grade powder should be stored in a well-closed container in a cool, dry place.

Synonyms:
Guar Gum
9000-30-0
Guaran
Guar
Guar flour
E89I1637KE
Gum guar
Jaguar
1212A
Burtonite V-7-E
Cyamopsis gum
Decorpa
Gendriv 162
Gum cyamopsis
Indalca AG
Indalca AG-BV
Indalca AG-HV
J 2Fp
Jaguar 6000
Jaguar A 20D
Jaguar A 40F
Jaguar gum A-20-D
Jaguar plus
Lycoid DR
NCI-C50395
Rein guarin
Supercol GF
Supercol U powder
Syngum D 46D
Uni-Guar
A-20D
Dealca TP1
Dealca TP2
FEMA No. 2537
Galactasol
JAGUAR A 20B
Jaguar A 20 B
Jaguar No.124
UNII-E89I1637KE
BURTONITE V 7E
CCRIS 321
CELBOND 7
CELCA-GUM D 49D
CYAMOPSIS TETRAGONOLOBA (GUAR) GUM
CYAMOPSIS TETRAGONOLOBA GUM
CYAMOPSIS TETRAGONOLOBUS
Cyamopsis tetragonoloba (L.) Taub. (Fabaceae)
DEALCA TP 1
DEALCA TP 2
DTXSID3020675
DYCOL 4500
E-412
EINECS 232-536-8
EINECS 293-959-1
EMCOGUM CSAA
EMULGUM 200
EMULGUM 200S
FFH 200
FG-HV
FINE GUM G
FINE GUM G 17
GALACTASOL 20H5FI
GALACTASOL 211
GALAXY 1083
GENDRIL THIK
GUAPACK PF 20
GUAPACK PN
GUAR 5200
GUAR GUM (II)
GUAR GUM (MART.)
GUAR SUPERCOL U FINE
GUARGEL D 15
GUM-CYAMOPSIS
GUMS, GUAR
Guar Gum Seed Endosperm
Guar gum (Cyamopsis tetragonolobus (L.))
Guar gum (cyamopsis tetragonolobus)
HSDB 1904
INS NO.412
INS-412
JAGUAR 170
JAGUAR 2100
JAGUAR 2513
JAGUAR 2610
JAGUAR 2638
JAGUAR 387
JAGUAR 6003
JAGUAR 8200
JAGUAR MDD
JAGUAR MDD-I
JAGUAR NO 124
K 4492
KWL 2000
LAMGUM 200
LEJ GUAR
LIPOCARD
LOLOSS
MEYPRO-GUAR CSAA 200/50
MEYPRO-GUAR CSAA-M 225
MEYPROGAT 30
MEYPROGUM L
MEYPROGUM TC 47
ORUNO G 1
PAK-T 80
PAPSIZE 7
RANTEC D 1
Solvent purified guar gum
Supercol G.F.
UNIGUAR 80
VIDOGUM G 200-1
VIDOGUM GH 175
VIDOGUM GHK 175
VIS TOP D 20
VIS TOP D 2022
VIS TOP LH 303
VISCOGUM HV 100T
VISCOGUM HV 3000A
X 5363
GUAR GUM THICKENER
Guar gum thickener, also known as guaran, comes from the seed of the Indian tree.
Guar seed is the combination of three things the germ, endosperm and the husk.
Guar seed is basically the legume which regenerates the nitrogen in soil.


CAS Number: 9000-30-0
EC Number: 232-536-8
MDL number: MFCD00131250
E number: E412 (thickeners, ...)
INCI Name: Cyamopsis Tetragonoloba (Guar) Gum



SYNONYMS:
Goma de guar, Gomma di Guar, Guar gum, Guarkernmehl, Guar, A-20D, J 2Fp, 1212A, Guaran, Jaguar, Decorpa, Regonol, Guar flour, Galactasol, Dealca TP2, NCI-C50395, Gendriv 162, Rein guarin, Supercol GF, Jaguar plus, Jaguar 6000, Jaguar A 40F, Jaguar A 20D, Syngum D 46D, Gum cyamopsis, Indalca AG-HV, FEMA No. 2537, Jaguar No.124, Supercol G.F., Indalca AG-BV, Cyamopsis gum, Jaguar A 20 B, Guar gum, ext., Burtonite V-7-E, UNII-E89I1637KE, Jaguar gum A-20-D, Supercol U powder, Guar Gum Seed Endosperm, Solvent purified guar gum, Guar gum (cyamopsis tetragonolobus), Guar gum (Cyamopsis tetragonolobus (L.)), Cyamopsis tetragonoloba (L.) Taub. (Fabaceae), Guar gum, Guar gum [NF], Guaran, 1212A, A-20D, Burtonite V-7-E, CCRIS 321, Cyamopsis gum, Cyamopsis tetragonoloba (L.) Taub. (Fabaceae), Dealca TP1, Dealca TP2, Decorpa, EINECS 232-536-8, FEMA No. 2537, Galactasol, Gendriv 162, Guar, Guar flour, Guar gum, Guar gum (Cyamopsis tetragonolobus (L.)), Guar gum (cyamopsis tetragonolobus), Guar Gum Seed Endosperm, Guaran, Gum cyamopsis, Gum guar, HSDB 1904, Indalca AG, Indalca AG-BV, Indalca AG-HV, J 2Fp, Jaguar, Jaguar 6000, Jaguar A 20 B, Jaguar A 20D, Jaguar A 40F, Jaguar gum A-20-D, Jaguar No.124, Jaguar plus, Lycoid DR, NCI-C50395, Regonol, Rein guarin, Solvent purified guar gum, Supercol G.F., Supercol GF, Supercol U powder, Syngum D 46D, Uni-Guar, UNII-E89I1637KE, Guar gum, Guar gum, 9000-30-0, E89I1637KE, 1312293-38-1, 53986-27-9, 57406-68-5, 57406-71-0, 63799-54-2, 85510-16-3, 9008-17-7, 9010-50-8, 9049-33-6, 9066-07-3, Cyamopsis psoraloides, Cyamopsis tetragonoloba, Cyamopsis tetragonolobus, Dietary Fiber, Dolichos psoraloides, Farine de Guar, Fibre Alimentaire, Goma Guar, Gomme de Guar, Gomme de Jaguar, Guar Flour, Indian Guar Plant, Jaguar Gum, Psoralea tetragonoloba



Guar gum thickener, also called guaran, is a galactomannan polysaccharide extracted from guar beans that has thickening and stabilizing properties useful in food, feed, and industrial applications.
The guar seeds are mechanically dehusked, hydrated, milled and screened according to application.


Guar gum thickener is typically produced as a free-flowing, off-white powder.
Guar gum thickener is a polysaccharide composed of the sugars galactose and mannose.
The backbone is a linear chain of ß 1,4-linked mannose residues to which galactose residues are 1,6-linked at every second mannose, forming short side-branches.


In water Guar gum thickener is nonionic and hydrocolloidal.
Guar gum thickener is not affected by ionic strength or pH, but will degrade at pH extremes at temperature (e.g. pH 3 at 50°C).
Guar gum thickener remains stable in solution over pH range 5-7.


Strong acids cause hydrolysis and loss of viscosity, and alkalies in strong concentration also tend to reduce viscosity.
Guar gum thickener is insoluble in most hydrocarbon solvents.
Before diving into Guar gum thickener benefits, let's first discuss what it is.


Guar gum thickener, also known as guaran, comes from the seed of the Indian tree.
This gum is created by removing the husks from the guar seeds.
The shells are then milled and sorted into the powder known as Guar gum thickener.


Commonly used as an additive in baking, Guar gum thickener works to improve the texture and shelf life of baked goods.
With eight times the thickening power of cornstarch, Guar gum thickener is an essential part of gluten free baking.
When using Guar gum thickener, it's important to remember that a little goes a long way.


Guar gum thickener has extremely high water-absorbing abilities.
This means that Guar gum thickener can instantly increase thickness, even when added to cold water.
However, adding too much Guar gum thickener to any recipe can result in bulky, stringy baked goods that are very high in fiber.


The color of Guar gum thickener is whitish and yellowish consisting of slight odor.
Cyamopsis tetragonolobus or Guar Plants endosperm derives Guar gum thickener.
Guar crop is basically a legume (a plant of a pea family) which grows effectively in sandy soils, with rainfall to some extent with lots of sunshine.


Food Grade Guar gum thickener is obtained from ground endosperm of guar plant.
The seed pods of Guar are grown in groups, 100 Kilos of beans, minus their bean pods yields roughly 29 kilos of endosperm; 29 kilos of Guar powder.
India Followed by Pakistan and US is the key producer of Guar Seeds constituting approximately 80% of the over all production.


Guar crop grows on semi arid and sub-tropical area harvested between Octobers to November.
Guar seed is the combination of three things the germ, endosperm and the husk.
Guar seed is basically the legume which regenerates the nitrogen in soil.


Green Guar is the source of vegetables and also fed to cattle’s.
Guar gum thickener can also be termed as the best and appropriate substitute for locust bean gum.
We offer goma guar as well as gomme guar from India.


Guar seeds are instantaneously sown after the first drizzles of the onset of monsoon i.e. in July.
The Hay of Guar is very nutritive making it a good fodder when mixed with wheat powder.
Guar seed can also be called as a cluster bean.


This Kharif legume is a highly nutritious crop used as green manure, vegetable and green fodder.
Guar Gum is extracted from Guar seeds and is grounded transforming it into Guar gum thickener.
Guar gum thickener is especially recommended for cold thickening of sauces with a fresh taste.


Guar gum thickener is the alternative to Xanthän for cold thickening.
Fiber-like carbohydrate of the galactomannan group, used in powder form as a thickener and stabilizer.
Its properties make Guar gum thickener a hydrocolloid.


Guar gum thickener comes from the seeds of a leguminous plant (Cyamopsis tetragonolobus), similar to the pea and native to India and Pakistan.
Guar is a white free flowing powder.
Guar gum thickener is completely soluble in hot or cold water to form a tasteless, odorless non toxic solution.


Guar gum thickener is a water soluble powder obtained from plant mucilage (Cyanopis tetragonoloba).
Guar gum thickener, a source of fiber, is a white powdery substance derived from guar seeds.
Often used as a food or cosmetic thickener, Guar gum thickener is eight times stronger than cornstarch.


Place Guar gum thickener in an empty salt shaker.
Guar gum thickener has a tendency to clump when added to liquids, so shake it into liquids while whisking at a high speed to keep your food smooth and thick.


Mix Guar gum thickener with liquids first.
Small amounts of Guar gum thickener can give fruit smoothies a milkshake texture.
Mix a pinch of Guar gum thickener with water or any other liquid used in your drink, and make sure all lumps are dissolved.


Use ¼ tsp. for every quart of liquid to prevent gelling.
Mix Guar gum thickener in dairy-based dressings for a thicker, more appealing appearance and texture, combining it with your liquid elements first.
Guar gum thickener is derived from the ground endosperm of the guar plant, Cyanmopsis tetragonolobus belonging to the family Leguminosae.


The guar plant is mainly grown in India and Pakistan from the month of July to December.
At harvest time, the seeds are extracted from the pod of the plant and then ground into Guar gum thickener.
Guar gum thickener is a polysaccharide that acts as a thickener, emulsifier, and stabilizer in cosmetic formulations.


Guar gum thickener has 8 times the water-thickening potency of cornstarch.
Guar gum thickener is water soluble.
When adding Guar gum thickener to a mixture it is best to add small quantities at a time.


Be sure to stir for a while after each addition.
If Guar gum thickener is added too quickly or in large quantities, it will gel or clump together.
Guar gum thickener works well in mixtures that freeze but not in extreme heat or in pH (above pH8 or below pH5).
Do not use if your formula contains Borax or Calcium.


Guar gum thickener is an extra-fine premium quality powder, which is a natural Gluten free food thickener, stabiliser, emulsifier and texture improver.
Guar gum thickener is a natural gluten-free food thickener used to thicken, bind, and emulsify gluten-free ingredients.
Guar gum thickener is a natural thickener, emulsifier, stabiliser and texture improver which is tasteless and has a neutral smell.


Guar gum thickener is a thickener for use in cosmetics, for example, shower gel or face cream.
Store Guar gum thickener dry, so do NOT store it in the refrigerator.
Also keep Guar gum thickener cool, dark and in the well-closed packaging.


Keep Guar gum thickener out of reach of children.
Guar gum thickener is preferred as thickeners for enhanced oil recovery (EOR).
Guar gum thickener and its derivatives account for most of the gelled fracturing fluids.


Guar gum thickener is more water-soluble than other gums, and it is also a better emulsifier, because it has more galactose branch points.
Guar gum thickener shows high low-shear viscosity, but it is strongly shear-thinning.
Being non-ionic, Guar gum thickener is not affected by ionic strength or pH but will degrade at low pH at moderate temperature (pH 3 at 50 °C).


Guar gum thickener's derivatives demonstrate stability in high temperature and pH environments.
Guar gum thickener use allows for achieving exceptionally high viscosities, which improves the ability of the fracturing liquid to transport proppant.
Guar gum thickener hydrates fairly rapidly in cold water to give highly viscous pseudoplastic solutions of, generally, greater low-shear viscosity than other hydrocolloid.


The colloidal solids present in Guar gum thickener make fluids more efficient by creating less filter cake.
Proppant pack conductivity is maintained by utilizing a fluid that has excellent fluid loss control, such as the colloidal solids present in Guar gum thickener.


Guar gum thickener is relatively cost effective as compared to other thickeners and stabilizers along with it being an effective binder, plasticizer and emulsifier.
One of the important properties of Guar gum thickener, a polysaccharide, is that it is high on galactose and mannose.


Guar gum thickener is also known as guarkernmehl, guaran, goma guar, gomme guar and galactomannan.
Guar gum thickener, also called Guaran by many, is a thickening agent which forms into a gel when it’s added to liquids, helping them bind together.
Guar gum thickener’s low in calories, high in soluble fiber, and also known to have higher thickening powers than cornstarch (really!).


Guar gum thickener becomes a gluten substitute in gluten-free cooking and baking, replacing regular flour.
Guar gum thickener comes from a cluster bean called Cyamopsis tetragonoloba, and it belongs to the legume family.
The seeds are broken and separated into parts.
The part referred to as the “undehusked guar split” is refined and made into a powder, while the remaining shells and seeds are used in animal feed.



USES and APPLICATIONS of GUAR GUM THICKENER:
In baked goods, Guar gum thickener increases dough yield, gives greater resiliency, and improves texture and shelf life; in pastry fillings, it prevents "weeping" (syneresis) of the water in the filling, keeping the pastry crust crisp.
Guar gum thickener is primarily used in hypoallergenic recipes that use different types of whole-grain flours.


Because the consistency of these flours allows the escape of gas released by leavening, Guar gum thickener is needed to improve the thickness of these flours, allowing them to rise as a normal flour would.
In dairy products, Guar gum thickener thickens milk, yogurt, kefir, and liquid cheese products, and helps maintain homogeneity and texture of ice creams and sherbets.


Guar gum thickener is used for similar purposes in plant milks.
For meat, Guar gum thickener functions as a binder.
In condiments, Guar gum thickener improves the stability and appearance of salad dressings, barbecue sauces, relishes, ketchups and others.


In canned soup, Guar gum thickener is used as a thickener and stabilizer.
Guar gum thickener is also used in dry soups, instant oatmeal, sweet desserts, canned fish in sauce, frozen food items, and animal feed.
The FDA has banned Guar gum thickener as a weight loss pill due to reports of the substance swelling and obstructing the intestines and esophagus.


For Cattle Feed, as Guar gum thickener enhances in the production of more milk as well as more percentage of fat in the milk.
Guar gum thickener is added in sauces, jams, dairy products, and baking mixes to give a good thickening to a product so that a nice consistency is achieved.
Industrial products which make massive use of Guar gum thickener include body lotions, instant soups, yogurts, coconut, bottled soya and almond milk.


Guar gum thickener has immense properties of stabilization, thickening, texturization, and emulsification.
Guar gum thickener has the property of getting dispersed into the water while hydrating and swelling quickly to form a viscous solution.
Guar gum thickener is primaraily used as a thickener in the food and cosmetic industry, and has a very high viscosity.


Unaffected by heat, flavorless, and gluten-free, Guar gum thickener works fab as a thickening agent in all forms.
Guar gum thickener makes Yoghurt.
Guar gum thickener improves the thickness of Ketchup.


Guar gum thickener adds thickness to Smoothies and Frappes.
Guar gum thickener is used to enhance the consistency of Salad Dressings.
Guar gum thickener acts as an excellent stabilizer in cold drinks such as ice cream, ice cream, ice cream, and borneol, preventing ice crystals from forming and thickening and emulsifying.


In noodle products such as noodles, dried noodles, instant noodles, and vermicelli, Guar gum thickener plays an excellent role in preventing sticking, retaining water, increasing gluten strength, and maintaining quality, and prolonging the shelf life.
In beverages such as peanut milk, almond milk, walnut milk, oranges, fruit juice, fruit tea, various solid beverages and eight-treasure porridge, Guar gum thickener acts as a thickening, water-holding and stabilizing agent, and improves the taste.


Guar gum thickener acts as a stabilizer in dairy products such as milk and yogurt, thickens, emulsifies, and improves the taste.
Guar gum thickener plays a stabilizing role in soy products such as tofu and soy milk.
In meat products, such as ham sausage, luncheon meat, and various meatballs, Guar gum thickener can bind, refresh and increase volume.


Condiments: In sauces and salad dressings, the basic property of Guar gum thickener, which produces high viscosity at low concentrations, is exploited to enhance the organoleptic qualities of these products, such as texture and rheology.
-Canned food uses of Guar gum thickener: The characteristic of this type of product is to contain as little liquid water as possible, and Guar gum thickener can be used to thicken the water in the product and make the solid part of the meat dish coated with a thick gravy.


Special, slow-swelling Guar gum thickener is sometimes used to limit viscosity when filling.
Use Guar gum thickener in bread, pastries or cake for a low-cost way to increase the volume of dough or batter.
Guar gum thickener also can be used in place of cornstarch in pie or pasty fillings to prevent the fruit from running.


Guar gum thickener is typically used in foods such as ice cream, smoothies, puddings and soups because of its water-absorbing properties.
Pharmaceuticals uses of Guar gum thickener: binder in tablet mixtures, thickener and emulsifier in food products for example cheese spreads, ice cream and other frozen deserts.


The resulting water solution of Guar gum thickener is pretty much tasteless, odourless and non toxic.
Guar gum thickener has 5-8 times the thickening power of starch.
For this reason Guar gum thickener is mainly used as a thickener and emulsifier in food products


Guar gum thickener is only to be used in small amounts in food as it can bind necessary liquids in your stomach and intestines and cause serious health issues.
Guar gum thickener can be used in lotions, gels and cosmetics because of its ability to mix oil and water.


Guar gum thickener is used for thickening cold and hot liquids, for hot jellies, light foams, for example: ice creams, juices, cottage cheese, marmelade, soups, sauces etc.
Guar gum thickener is also used for gluten free baking – gellan gum acts as a binder and gives a softer texture.


Use Guar gum thickener when creating dry soup mixes.
Follow your recipe exactly, and use ¼ tsp. for every quart of liquid used.
The Guar gum thickener will bind to the water or broth, creating a luxurious and thick texture.


Use Guar gum thickener in gluten-free baking.
The gluten in wheat acts as a protein binder in bread, creating a chewy texture.
When you omit wheat from your recipe, your bread will fall flat.


Guar gum thickener will replace gluten as a binder, allowing you to achieve the same chewy results.
Texture: jelly made with Guar gum thickener is tight, sticky, stable on PH 4-10, opaque.
Guar gum thickener will not bind well with alcohol.


With alginate and xanthan gum makes extra strong jellies.
For mild jellies (using opaque liquids, like milk) use 0,35% Guar gum thickener.
For warm jellies use 0,5 Guar gum thickener and 0,35% xanthan gum (hot soups, sauces).


For hot jellies, terrins, what can be cut, use 0,2% Guar gum thickener and 0,4% agar agar.
Guar gum thickener thickener is water soluble.
When adding Guar gum thickener to a mixture it is best to add small quantities at a time.


Be sure to stir for a while after each addition.
If Guar gum thickener is added too quickly or in large quantities, it will gel or clump together.
Guar gum thickener works well in mixtures that freeze but not in extreme heat or in pH (above pH8 or below pH5).


Do not use if your formula contains Borax or Calcium.
Only a small amount of Guar gum thickener is needed to increase the viscosity of a product (.5%-1%).
Guar gum thickener can be used in soaps to help achieve better emulsions, and as a whitening agent.


Guar gum thickener can be used in lotion, cream, and ointment recipes as an emulsifier, thickener, and stabilizer.
Suggested rate of usage of Guar gum thickener in a recipe is .5%-2%.
Guar gum thickener can be used in shampoo, conditioner, and liquid soap recipes to increase viscosity, and to allow solid particles to be suspended in the product.


Guar gum thickener can be used in natural toothpaste recipes.
Guar gum thickener can be used in mascara making.
Guar gum thickener is a powerful short texture thickener and can be used in cold water or liquids.


Guar gum thickener is neutral in smell and tasteless.
Guar gum thickener is used to thicken, bind ingredients and reduce water leakage, it can be used in bread and dough for a softening effect.
Use of Guar gum thickener in gels, fruit preparations and frozen products to prevent water leakage or to thicken.


Guar gum thickener is used in ice cream and sorbets to prevent ice crystals from forming.
Guar gum thickener can also be used in foams to improve stability and texture and can replace starch, syrups and sugars as a low-calorie source thickener.
In Vegan and Vegetarian food, Guar gum thickenercan be used as a binder to replace eggs or forms of protein.


Guar gum thickener is suitable for Vegans & Vegetarians, Non-GMO, Gluten Free.
Guar gum thickener can be used in cold applications.
Add Guar gum thickener to bread and dough to create a softening effect.


Add Guar gum thickener to gels, fruit preparations and frozen products to prevent water leakage and ice crystals forming.
Guar gum thickener is suitable for Vegans & Vegetarians, Non-GMO, Gluten Free.
Guar gum thickener is best used in foods that are not-heated ie. raw baking, making low-carb ice cream etc.


In creams, lotions and, for example, body butter, a thickener can be used to stabilize the emulsion.
It prevents separation into an aqueous layer and an oily layer.
For example, use a small amount (0,1-0,5 grams per 100 grams) of Guar gum thickener in the water phase.


The easiest way is to mix Guar gum thickener with a little glycerine, propylene glycol or, for example, a liquid preservative, in any case with a viscous liquid that is used in the water phase.
Guar gum thickener mixes with a minimal risk of lump formation.


In addition, Guar gum thickener can be used for thickening, for example, shampoo, shower gel and other water-based cosmetics.
Mix Guar gum thickener with the surfactants before adding the water.
Use 0,5-2% Guar gum thickener.


The shampoo may turn opaque.
A completely different application is when used in 'slime', in which approximately 1% Guar gum thickener is used to make a thin slime, and a borax solution with which it can be further thickened by cross linking.
Guar gum thickener has up to eight times the thickening power of starch.


Derivatization of Guar gum thickener leads to subtle changes in properties, such as decreased hydrogen bonding, increased solubility in water-alcohol mixture, and improved electrolyte compatibility.
These changes in properties result in increased use in different fields, like textile printing, explosives, and oil-water fracturing applications.


-Guar gum thickener is mostly used as a thickener and stabilizer.
Different types of Guar gum thickener have different uses in:
*Food
*Medicine
*Paper
*Cosmetics
*Textiles
*Explosives
*Oil well drilling‌


-Guar gum thickener as a Thickening Agent in Mayonnaise.
Guar gum thickener powder is derived from Guar gum thickener also known as guaran. Guar gum thickener is extracted from guar beans.
The Guar seeds are processed mechanically using several procedures like debusking, hydrating.

They are later screened as per the application to produce a free-flowing powder (off-white in colour).
The plant Guar Bean is mainly found in India and Pakistan.
A large percentage of this is produced in India.


-Industrial applications of Guar gum thickener:
*Textile industry – sizing, finishing and printing
*Paper industry – improved sheet formation, folding and denser surface for printing
*Explosives industry – as waterproofing agent mixed with ammonium nitrate, nitroglycerin, etc.
*Pharmaceutical industry – as binder or as disintegrator in tablets; main ingredient in some bulk-forming laxatives
*Cosmetics and toiletries industries – thickener in toothpastes, conditioner in shampoos (usually in a chemically modified version)
*Fracturing fluids normally consist of many additives that serve two main purposes, firstly to enhance fracture creation and proppant carrying capability and secondly to minimize formation damage.
*Viscosifiers, such as polymers and crosslinking agents, temperature stabilizers, pH control agents, and fluid loss control materials are among the additives that assist fracture creation.
*Formation damage is minimized by incorporating breakers, biocides, and surfactants.
*More appropriate gelling agents are linear polysaccharides, such as guar gum, cellulose, and their derivatives.


-Food applications
The largest market for Guar gum thickener is in the food industry.
In the US, differing percentages are set for Guar gum thickener's allowable concentration in various food applications.
In Europe, Guar gum thickener has EU food additive code E412.
Xanthan gum and Guar gum thickener are the most frequently used gums in gluten-free recipes and gluten-free products.


-Guar gum thickener in food:
When it comes to food use, Guar gum thickener is most often used in gluten-free foods.
The gluten in flour is what provides the texture and elasticity common in bread.
Flour alternatives don’t work as well for baking, and Guar gum thickener can provide the same qualities as gluten.
Chia seeds and psyllium husk are other alternatives that act similarly to Guar gum thickener.‌


-Other foods that can benefit from Guar gum thickener include:
*Fried foods:
Guar gum thickener reduces the amount of oil absorbed by the food during frying.
*Yogurt:
Guar gum thickener can make the texture creamier.
*Cake:
Guar gum thickener replaces fat and boosts the firmness.
*Pasta:
Guar gum thickener improves the texture.
*Ketchup:
Guar gum thickener gives it a thicker consistency.
*Drinks:
Guar gum thickener gives a longer shelf life to some drinks.
*Cheese:
Guar gum thickener keeps cheese from weeping and becoming soggy, giving it a longer shelf life. ‌
*Meat products – In meats that are stuffed, like sausage, Guar gum thickener keeps fat from separating and also controls liquid.



GUAR GUM THICKENER AS A THICKENING AGENT:
The fact that Guar gum thickener has good chemical and physical structure makes it one of the chosen additives form several food products.
Guar gum thickener's water solubility capability helps create a thick structure.
As an additive Guar gum thickener is extremely useful as a thickening agent, binding agent, stabilizer and emulsifier.

Guar gum thickener is useful for several applications and has there are many advantages of using it.
Guar gum thickener can reduce the baking time.
Guar gum thickener replaces flour in baked food making it easier to digest.

Guar gum thickener helps increase the shelf life of food products.
Its excellent ability to absorb excess liquid makes Guar gum thickener an excellent thickener.
Guar gum thickener is optimal to produce low-calorie food and is useful in reducing oil content.



ROLE OF THICKENING AGENT IN MAYONNAISE, GUAR GUM THICKENER:
Mayonnaise is a thick sauce that is made from oil (it is also creamy), egg yolk, lemon juice, vinegar and seasonings.
Mayonnaise is essentially an emulsion of two liquids that will not mix where the ingredients may vary as per preference.
The method of obtaining an emulsion is to gradually add one ingredient to another while rapidly mixing the ingredients.

Guar gum thickener is vital for mayonnaise to provide necessary viscosity.
The main aim of the Guar gum thickener is to improve good texture; the benefit being it will taste better and help the flavour have a greater impact on your taste buds.

As far as mayonnaise is concerned Guar gum thickener uses an emulsion of fats and liquids.
Guar gum thickener is optimal for use as a thickening agent in mayonnaise.



HOW TO USE GUAR GUM THICKENER:
Now that you understand where Guar gum thickener comes from, the next step is learning how to use guar gum.
Used to stabilize and thicken the texture of various foods, Guar gum thickener can be added to everything from coconut milk to brownies.



GLUTEN FREE BAKING, GUAR GUM THICKENER:
Guar gum thickener and gluten free baking go hand in hand.
Often, when switching to a gluten free lifestyle, creating your favorite baked treats is one of the biggest challenges you'll face.
Because gluten plays such a crucial role in creating the right texture in baked goods, Guar gum thickener can be hard to achieve the feel and structure of traditional bread and dessert recipes without it.

That's where Guar gum thickener comes into play!
If you're baking with flours that don't have gluten in them, adding Guar gum thickener to the recipe can help add some elasticity to your dough.
The kind of flexibility that would usually be produced by gluten.

Guar gum thickener allows you to make a gluten free treat that has the same texture as a traditional one, hence why we love it so much.
The recipe you choose to create will significantly affect how much Guar gum thickener needs to be used.
Bread recipes typically call for more Guar gum thickener and can use up to a teaspoon of it per every cup of gluten free flour.



THICKEN SAUCES, GUAR GUM THICKENER:
At first, thickening sauces may seem like an easy task.
After all, flours and starches like cornstarch, arrowroot and tapioca can all be added to your favorite soup recipe.
The problem?

All of these flours and starches have different qualities, and knowing which one to use can be challenging.
Plus, if you're following a low carb diet or keto diet, even a tablespoon of these starches can drastically affect the nutritional content of the dish.
Guar gum thickener is a great replacement thickener, and because it's flavorless it can be added to just about any recipe.

In fact, Guar gum thickener has a significant advantage over other thickeners: it's not affected by heat!
The molecules in starches like arrowroot powder and tapioca powder can be drastically affected by temperature.
When added to a recipe that's too hot or cold, these thickeners are not able to do their job.

Because Guar gum thickener doesn't need heat to work correctly, it can be added to hot and cold dishes, while still maintaining it's thickening properties.
Add Guar gum thickener to recipes like salad dressings or your favorite smoothie to perfect the consistency of the plate.




MINING, GUAR GUM THICKENER:
Hydroseeding – formation of seed-bearing "guar tack"
Medical institutions, especially nursing homes - used to thicken liquids and foods for patients with dysphagia
Fire retardant industry – as a thickener in Phos-Chek
Nanoparticles industry – to produce silver or gold nanoparticles, or develop innovative medicine delivery mechanisms for drugs in pharmaceutical industry.
Slime (toy), based on Guar gum thickener crosslinked with sodium tetraborate



CROSSLINKING, GUAR GUM THICKENER:
Guar molecules have a tendency to aggregate during the hydraulic fracturing process, mainly due to intermolecular hydrogen bonding.
These aggregates are detrimental to oil recovery because they clog the fractures, restricting the flow of oil.
Cross-linking guar polymer chains prevents aggregation by forming metal – hydroxyl complexes.

The first crosslinked guar gels were developed in the late ‘60s.
Several metal additives have been used for crosslinking, among them are chromium, aluminium, antimony, zirconium, and the more commonly used, boron.
Boron, in the form of B(OH)4, reacts with the hydroxyl groups on the polymer in a two step process to link two polymer strands together to form bis-diol complexes.

1:1 1,2 diol complex and a 1:1 1,3 diol complex, place the negatively charged borate ion onto the polymer chain as a pendant group.
Boric acid itself does not apparently complex to the polymer so that all bound boron is negatively charged.
The primary form of crosslinking may be due to ionic association between the anionic borate complex and adsorbed cations on the second polymer chain .

The development of cross-linked gels was a major advance in fracturing fluid technology.
Viscosity is enhanced by tying together the low molecular weight strands, effectively yielding higher molecular weight strands and a rigid structure.
Cross-linking agents are added to linear polysaccharide slurries to provide higher proppant transport performance, relative to linear gels.

Lower concentrations of guar gelling agents are needed when linear guar chains are cross-linked.
It has been determined that reduced guar concentrations provide better and more complete breaks in a fracture.
The breakdown of cross-linked guar gel after the fracturing process restores formation permeability and allows increased production flow of petroleum products.



ADVANTAGES OF GUAR GUM THICKENER:
Guar gum thickener possesses double the ability to thicken than flour and almost eight times that of the corn starch powder
Guar gum thickener's usage avoids the formation of any lump and does not break down easily like the corn starch.

Guar gum thickener eliminates the need for heat to thicken and can get to hydrate itself very quickly
Experts suggest the appropriate ratio which works well with Ethylene Oxide free Guar gum thickener manufacturers as an excess of it may form lumps in the whole recipe

Almost Seventy Percent of the food industry applications of the fast-paced industries use the Guar gum thickener due to its varied and multiple benefits.
Guar gum thickener is also expected to grow exponentially looking at the current demand scenario.

It is always wise to opt for a reputed Ethylene Oxide free Guar gum thickener exporter as this miraculous powder offers health benefits like reduction of weight and easy bowel movement.
Guar gum thickener needs to be boiled in hot water and is beneficial for people who want a reduction of weight as it reduces the calories inside the human body.



WHY DO WE USE GUAR GUM THICKENER IN FORMULATIONS?
Guar gum thickener is used to thicken water-based products.
Guar gum thickener can be used as the sole gelling/thickening agent in products like gels or body washes, or can be incorporated at lower amounts (typically 0.5% or less) to thicken and stabilize emulsions.


DO YOU NEED GUAR GUM THICKENER?
No


STRENGHTS OF GUAR GUM THICKENER:
Inexpensive, natural, vegan thickening agent.


WEAKNESSES OF GUAR GUM THICKENER:
Gels made solely with Guar gum thickener tend to have a snotty consistency, and I really don’t like how they feel on the skin when they dry down.


ALTERNATIVES AND SUBSTITUTIONS OF GUAR GUM THICKENER:
I prefer hydroxyethylcellulose, but xanthan gum can also work.


HOW TO WORK WITH GUAR GUM THICKENER:
Whisk the Guar gum thickener into something from your formula other than water to create a slurry; glycerine is a good choice, or a liquid oil.
This allows us to distribute the gum without Guar gum thickener starting to hydrate, which will cause it to clump and create “fish eyes” in our product.
Once Guar gum thickener has been thoroughly dispersed in the non-water medium you can start to slowly incorporate the water.
Gentle heating will speed the thickening process, but Guar gum thickener is not necessary.


STORAGE AND SHELF LIFE OF GUAR GUM THICKENER:
Stored somewhere cool, dark, and dry, Guar gum thickener should last at least two years.


TIPS, TRICKS, AND QUIRKS OF GUAR GUM THICKENER:
One can also purchase cationic guar (Guar hydroxypropyltrimonium chloride).
This is not the same ingredient and they are not interchangeable.



PROS OF GUAR GUM THICKENER:
*‌Eating options:
If you have trouble digesting gluten, you know it can be challenging to find alternatives to common foods.
Using Guar gum thickener lets you prepare and enjoy foods that would otherwise be off-limits.
Using Guar gum thickener in baking gives the dough the sticky elasticity that is so important.
Guar gum thickener provides the desired texture and consistency when you can’t use regular flour.

*Possible health perks:
Guar gum thickener can boost the fiber in your diet.
Guar gum thickener may also help lower cholesterol, blood sugar, and the risk of heart disease.
You may feel more full after eating, too.
This feeling of fullness might help you lose extra weight.



IMPROVE THE CONSISTENCY OF FROZEN GOODS OF GUAR GUM THICKENER:
Now that you know that Guar gum thickener doesn't need heat to do its job, you might be wondering if it works just as well in frozen recipes.
It does!

Guar gum thickener is a great ingredient to have on hand if you're working within certain dietary restrictions.
Gluten free, vegan and keto-friendly, Guar gum thickener can help you navigate through some of the most stringent dietary restrictions.
Adding Guar gum thickener to frozen desserts like ice cream, popsicles and smoothies work to create a smoother and softer consistency.

Doing so will help keep your frozen foods from turning into ice-like blocks.
Guar gum thickener can also be used when making jams.
Just add a bit of Guar gum thickener to sweet berries or fresh fruit for the perfect refrigerator jam.

While Guar gum thickener has several benefits, primarily when used in gluten free cooking, it can come with some potential disadvantages.
Again, due to its high fiber content, too much Guar gum thickener can cause digestive upset in sensitive individuals.
Because of this, Guar gum thickener's not recommended that for anyone to consume a lot of it.
However, when used in moderation, Guar gum thickener's a much more natural choice than other options.



MEASUREMENTS OF GUAR GUM THICKENER:
Now, it's time to put your Guar gum thickener knowledge to use and start cooking!
As we mentioned before, Guar gum thickener's important to remember that a little bit of Guar gum thickener goes a long way.
While measurements will vary depending on which recipe you're making, it's essential not to overdo it when adding Guar gum thickener.
It's recommended that no matter what you're cooking up, never use more than a tablespoon of Guar gum thickener in a recipe.



CHARACTERISTICS AND APPLICATIONS OF GUAR GUM THICKENER:
Guar gum thickener is soluble in cold water and provides high viscosity.
Guar gum thickener is applied to products that have to be subjected to high temperatures and, in general, as a complement to other thickening ingredients.
In gastronomy Guar gum thickener is used to make fresh cheeses, ice cream, croquettes, sauces, bakery products, jams, jellies, marmalades, etc.



NUTRITIONAL AND MEDICINAL EFFECTS OF GUAR GUM THICKENER:
Guar gum thickener, as a water-soluble fiber, acts as a bulk-forming laxative.
Several studies have found Guar gum thickener decreases cholesterol levels.
These decreases are thought to be a function of Guar gum thickener's high soluble fiber content.

Moreover, Guar gum thickener's low digestibility lends its use in recipes as a filler, which can help to provide satiety or slow the digestion of a meal, thus lowering the glycemic index of that meal.
In the late 1980s, Guar gum thickener was used and heavily promoted in several weight-loss drugs.



PROPERTIES OF GUAR GUM THICKENER:
*Guar gum thickener has reasonably more thickening property as compared to corn starch.
*Holds back the growth of ice crystal
*Guar is draught resistant plant
*Guar gum thickener forms gel in water
*Endosperm of guar seeds are used in many sectors of industries like mining, petroleum, drilling and textile., food products, pharmaceuticals, cosmetics, water treatment, mining, drilling,confectioneries and many more.
*Since a long time Guar gum thickener can be also named as a hydrocolloid, is treated as the key product for humans and animals as it has a very high nourishing property.



BENEFITS OF GUAR GUM THICKENER:
*Lowering blood Glucose
*Lowering insulin levels



PROPERTIES OF GUAR GUM THICKENER:
Guar gum thickener consists of the ground seeds of the guar plant or Cyamopsis tetragonoloba (L.) Taub.
Country of origin is India.
Guar gum thickener largely consists of plant gums.
Guar gum thickener is able to bind water to a mucus or gel.



MAIN PROPERTIES OF GUAR GUM THICKENER:
Guar gum thickener has several useful properties that make it vital for several applications in many different industries.
Guar gum thickener's ability to hydrate in quick time in cold water and attain a high level of viscosity even with low concentration is highly beneficial.
The fact that Guar gum thickener is soluble in cold water and also provides full viscosity in cold water is also taken advantage off for many applications.



HERE ARE THE MAIN PROPERTIES OF GUAR GUM THICKENER:
Guar gum thickener is an excellent thickening agent.
Guar gum thickener is an efficient and cost-effective stabilizer and emulsifier.
Guar gum thickener provides good texture, water-binding and prevents crystal formation.

Guar gum thickener is soluble in cold water but not in many organic solvents.
Guar gum thickener has good film-forming property.
Guar gum thickener possess excellent hydrogen properties.



A PERSONAL ICE CREAM MAKER,
If you’ve tried making ice cream at home, had a bowl full of that, and then ventured to your nearest ice cream parlor to have a scoop of your favorite ice cream, you’ll notice a difference.
It's just creamier, thicker, fluffier, and all over better – isn't it?

And no, this one’s not your fault.
It’s because the soft serves we so love to purchase usually come bound with a thickening agent.
Now, with Guar gum thickener, you can add the same consistency to homemade ice cream – Yass!
I scream, you scream, we all scream for ice cream!

Basically, Guar gum thickener stops frozen items from melting because melting is what happens upon heat contact post-crystal formation.
When you add Guar gum thickener to your ice creams, its emulsifying properties mean ice crystals don’t get formed, and your frozen item doesn’t turn into a block of ice.

Get the feeling of a soft serve as the ice cream or popsicle gents melts without going all runny or watery.
Think smooth, think buttery soft, think Guar gum thickener!
And ice cream isn’t the only cold goodie you can make using Guar gum thickener.

Jams are another possibility.
Add Guar gum thickener to your fresh fruits and turn them into jam without fearing crystallizations or weird consistencies and get a jello-like jam that spreads easily on toast.



SHELF-LIFE ENHANCER OF GUAR GUM THICKENER:
This is something everybody’s not really going to tell you about Guar gum thickener, but you eventually find out after testing and trying it in several recipes.
Guar gum thickener works great in improving the shelf life of food items, and we don’t just mean baked goods but also meats, cheeses, and beverages.

Imagine that!
Let’s see how.
In meat products, Guar gum thickener helps with viscosity control.

Guar gum thickener keeps the fat from separating and absorbs the excess water and liquids, making the meat prep process easier and helping in preservation.
Stuffed meats like sausages especially gain from this.
Let’s move on to cheese.

Guar gum thickener prevents the cheese from becoming soggy or weeping.
So, the Guar gum thickener will essentially last longer, and you can use it with longer intervals.
After all, Guar gum thickener's not every day that you end up making a cheese snack on a gluten-free/vegan diet.

Next up, canned stuff.
From gravies and instant mix products to condiments and even beverages, Guar gum thickener improves thickening and locks in moisture for easier storage and longer shelf life of packaged mixes.



THICKENING OF GUAR GUM THICKENER:
One use of Guar gum thickener is a thickening agent in foods and medicines for humans and animals.
Because it is gluten-free, Guar gum thickener is used as an additive to replace wheat flour in baked goods.
Guar gum thickener has been shown to reduce serum cholesterol and lower blood glucose levels.

Guar gum thickener is also economical because it has almost eight times the water-thickening ability of other agents (e.g. cornstarch) and only a small quantity is needed for producing sufficient viscosity.
Because less is required, Guar gum thickener costs are reduced.

In addition to Guar gum thickener's effects on viscosity, its high ability to flow, or deform, gives it favorable rheological properties.
Guar gum thickener forms breakable gels when cross-linked with boron.
Guar gum thickener is used in various multi-phase formulations for hydraulic fracturing, in some as an emulsifier because it helps prevent oil droplets from coalescing, and in others as a stabilizer to help prevent solid particles from settling and/or separating.

Fracking entails the pumping of sand-laden fluids into an oil or natural gas reservoir at high pressure and flow rate.
This cracks the reservoir rock and then props the cracks open.
Water alone is too thin to be effective at carrying proppant sand, so Guar gum thickener is one of the ingredients added to thicken the slurry mixture and improve its ability to carry proppant.

There are several properties which are important
1. Thixotropic: the fluid should be thixotropic, meaning it should gel within a few hours.
2. Gelling and de-gelling: The desired viscosity changes over the course of a few hours.

When the fracking slurry is mixed, it needs to be thin enough to make it easier to pump.
Then as it flows down the pipe, the fluid needs to gel to support the proppant and flush it deep into the fractures.

After that process, the gel has to break down so that it is possible to recover the fracking fluid but leave the proppant behind.
This requires a chemical process which produces then breaks the gel cross-linking at a predictable rate.
Guar+boron+proprietary chemicals can accomplish both of these goals at once.



ICE CRYSTAL GROWTH, GUAR GUM THICKENER:
Guar gum thickener retards ice crystal growth by slowing mass transfer across the solid/liquid interface.
Guar gum thickener shows good stability during freeze-thaw cycles.
Thus, Guar gum thickener is used in egg-free ice cream.

Guar gum thickener has synergistic effects with locust bean gum and sodium alginate.
May be synergistic with xanthan: together with xanthan gum, Guar gum thickener produces a thicker product (0.5% guar gum / 0.35% xanthan gum), which is used in applications such as soups, which do not require clear results.

Guar gum thickener is a hydrocolloid, hence is useful for making thick pastes without forming a gel, and for keeping water bound in a sauce or emulsion.
Guar gum thickener can be used for thickening cold and hot liquids, to make hot gels, light foams and as an emulsion stabilizer.
Guar gum thickener can be used for cottage cheeses, curds, yoghurt, sauces, soups and frozen desserts.
Guar gum thickener is also a good source of fiber with 80% soluble dietary fiber on a dry weight basis.



HOW IS GUAR GUM THICKENER MADE?
This might get a little technical, so bear with us.
Guar gum thickener powder comes from the cluster bean plant (guar) that’s mostly found in India.
The seeds of the tree are called guar beans and they are dehusked mechanically i.e., basically split into parts.
The shells (or unhusked guar split) are hydrated, milled, and refined to form a powder that is the gum itself.
While the remaining part eventually becomes a part of animal feed, ensuring minimal wastage (unrelated but interesting fact).



WHAT IS THE PURPOSE OF GUAR GUM THICKENER?
Guar gum thickener is a stabilizer and thickener.
Guar gum thickener has incredibly high water-absorbing abilities, and so it can immediately thicken whatever it’s added to.
Even water.

This makes Guar gum thickener a fabulous ingredient for several uses.
Different sorts of Guar gum thickener are used in producing medicines, papers, textiles, cosmetics, food of course, and even explosives.
Imagine how versatile this seemingly simple powder is.

But today's focus is only going to be on how you can add the magic of Guar gum thickener to your recipes.
Let’s get into it.



GUAR GUM THICKENER VS. TARA GUM
Tara gum is part of the same chemical family as Guar gum thickener.
Both of them have a similar molecular structure known as galactomannans.
Tara has similar cold water solubility to Guar gum thickener.
Tara gum has very similar thickening characteristics to Guar gum thickener but has some advantages.



PRODUCTION AND TRADE OF GUAR GUM THICKENER:
The guar bean is principally grown in India, Pakistan, the United States, Australia and Africa.
India is the largest producer, accounting for nearly 80% of the world production.
In India, Rajasthan, Gujarat, and Haryana are the main producing regions.

The US has produced 4,600 to 14,000 tonnes of guar over the last 5 years.
Texas acreage since 1999 has fluctuated from about 7,000 to 50,000 acres.
The world production for Guar gum thickener and its derivatives is about 1.0 million tonnes.
Non-food Guar gum thickener accounts for about 40% of the total demand.



PROPERTIES OF GUAR GUM THICKENER:
*Chemical composition
Chemically, Guar gum thickener is an exo-polysaccharide composed of the sugars galactose and mannose.

The backbone is a linear chain of β 1,4-linked mannose residues to which galactose residues are 1,6-linked at every second mannose, forming short side-branches.
Guar gum thickener has the ability to withstand temperatures of 80 °C (176 °F) for five minutes.


*Solubility and viscosity
Guar gum thickener is more soluble than locust bean gum due to its extra galactose branch points.
Unlike locust bean gum, Guar gum thickener is not self-gelling.

Either borax or calcium can cross-link Guar gum thickener, causing it to gel.
In water, Guar gum thickener is nonionic and hydrocolloidal.
Guar gum thickener is not affected by ionic strength or pH, but will degrade at extreme pH and temperature (e.g. pH 3 at 50 °C).

Guar gum thickener remains stable in solution over pH range 5–7.
Strong acids cause hydrolysis and loss of viscosity and alkalies in strong concentration also tend to reduce viscosity.
Guar gum thickener is insoluble in most hydrocarbon solvents.

The viscosity attained is dependent on time, temperature, concentration, pH, rate of agitation and particle size of the powdered gum used.
The lower the temperature, the lower the rate at which viscosity increases, and the lower the final viscosity.
Above 80°, the final viscosity is slightly reduced.

Finer guar powders swell more rapidly than larger particle size coarse powdered gum.
Guar gum thickener shows a clear low shear plateau on the flow curve and is strongly shear-thinning.
The rheology of Guar gum thickener is typical for a random coil polymer.

Guar gum thickener does not show the very high low shear plateau viscosities seen with more rigid polymer chains such as xanthan gum.
Guar gum thickener is very thixotropic above 1% concentration, but below 0.3%, the thixotropy is slight.
Guar gum thickener shows viscosity synergy with xanthan gum.
Guar gum thickener and micellar casein mixtures can be slightly thixotropic if a biphase system forms.



MANUFACTURING PROCESS OF GUAR GUM THICKENER:
Depending upon the requirement of end product, various processing techniques are used.
The commercial production of Guar gum thickener normally uses roasting, differential attrition, sieving, and polishing.
Food-grade Guar gum thickener is manufactured in stages.

Guar split selection is important in this process.
The split is screened to clean it and then soaked to pre-hydrate Guar gum thickener in a double-cone mixer.
The prehydrating stage is very important because it determines the rate of hydration of the final product.

The soaked splits, which have reasonably high moisture content, are passed through a flaker.
The flaked guar split is ground and then dried.
The powder is screened through rotary screens to deliver the required particle size.

Oversize particles are either recycled to main ultra fine or reground in a separate regrind plant, according to the viscosity requirement.
This stage helps to reduce the load at the grinder.
The soaked splits are difficult to grind.

Direct grinding of those generates more heat in the grinder, which is not desired in the process, as it reduces the hydration of the product.
Through the heating, grinding, and polishing process, the husk is separated from the endosperm halves and the refined guar split is obtained.
Through the further grinding process, the refined guar split is then treated and converted into powder.

The split manufacturing process yields husk and germ called “guar meal”, widely sold in the international market as cattle feed.
It is high in protein and contains oil and albuminoids, about 50% in germ and about 25% in husks.
The quality of the food-grade Guar gum thickener is defined from its particle size, rate of hydration, and microbial content.

Manufacturers define different grades and qualities of Guar gum thickener by the particle size, the viscosity generated with a given concentration, and the rate at which that viscosity develops.
Coarse-mesh Guar gum thickeners will typically, but not always, develop viscosity more slowly.

They may achieve a reasonably high viscosity, but will take longer to achieve.
On the other hand, they will disperse better than fine-mesh, all conditions being equal.
A finer mesh, such as a 200 mesh, requires more effort to dissolve.
Modified forms of Guar gum thickener are available commercially, including enzyme-modified, cationic and hydropropyl guar.



PHYSICAL and CHEMICAL PROPERTIES of GUAR GUM THICKENER:
Density: 0.8-1.0 g/mL at 25 °C
Acidity (pKa): 5-7
Physical state: powder
Color: beige
Odor: No data available
Melting point/freezing point: no data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Appearance: White-like powder
Storage Condition: Room Temprature



FIRST AID MEASURES of GUAR GUM THICKENER:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of GUAR GUM THICKENER:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of GUAR GUM THICKENER:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of GUAR GUM THICKENER:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Choose body protection.
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of GUAR GUM THICKENER:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of GUAR GUM THICKENER:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
Guar Hydroxypropyltrimonium Chloride is a water-soluble, organic compound that is a quaternary ammonium derivative of guar (aka cluster beans).
This means Guar Hydroxypropyltrimonium Chloride is a substance whose chemical structure has four carbon groups attached to a positively charged nitrogen atom.
While plant derived, there is a synthetic portion to Guar Hydroxypropyltrimonium Chloride.


CAS No: 65497-29-2
EC Number: 613-809-4
Origin(s): Vegetal, Synthetic
INCI name: GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
Classification: Quaternary ammonium cation, Propoxylated compound
Bio-compatible
Chem/IUPAC Name: Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride
Molecular Formula: C6H16NO2


Guar Hydroxypropyltrimonium Chloride is identified as a white or yellow like powder.
With Guar Hydroxypropyltrimonium Chloride you can get non-static silky hair.
Guar Hydroxypropyltrimonium Chloride also helps it retain volume and makes it easier to manage.


So basically Guar Hydroxypropyltrimonium Chloride is amazing for your hair.
Guar Hydroxypropyltrimonium Chloride, GHPT for short, is a water-soluble quaternary ammonium modifier of guar gum.
Guar Hydroxypropyltrimonium Chloride is a compound that is water soluble.


Although a great conditioning agent for both hair and scalp, Guar Hydroxypropyltrimonium Chloride most definitely gives the biggest benefits to your strands of hair.
Guar Hydroxypropyltrimonium Chloride is a cationic surfactant that has been shown to be effective in the treatment of vaginal atrophy.


Guar Hydroxypropyltrimonium Chloride has been shown to be an excellent antimicrobial agent for the prevention and treatment of microbial infection.
Guar Hydroxypropyltrimonium Chloride is a quaternary ammonium derivative of guar gum; used in hair conditioning products.
Guar Hydroxypropyltrimonium Chloride is used conditioning chemical added to hair products for easy detangling


Guar Hydroxypropyltrimonium Chloride is a yellow free-flowing powder
Guar hydroxypropyltrimonium chloride is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
Guar Hydroxypropyltrimonium Chloride gives conditioning properties to shampoos and after-shampoo hair care products.


Guar Hydroxypropyltrimonium Chloride is a hydroxypropylated cationic guar derivative that provides conditioning benefits.
The cationic charge of Guar Hydroxypropyltrimonium Chloride interacts with keratin providing a conditioning effect on hair and skin and reducing the negative effects of soaps and surfactants.


Though cationic, Guar Hydroxypropyltrimonium Chloride is compatible with most anionic and amphoteric surfactants.
Guar Hydroxypropyltrimonium Chloride is not sensitive to electrolytes and due to the hydropropylation shows higher hydrophilic characteristics when compared to other cationic guars.


Guar Hydroxypropyltrimonium Chloride is soluble in water at room temperature (pH adjusted to 5.5-6.0), partially soluble in aqueous methanol or ethanol solutions and insoluble in paraffin oil, petroleum ether, chloroform and ethyl ether.
Cyamopsis Tetragonoloba (Guar) Gumb (also called Guar Gum) is a resinous material made from the guar bean.


Guar Gum is a type of polysaccharide called galactomannan made from legume plants that consists of a polymannose backbone to which galactose groups are bound.
Derivatives of Guar Gum that also may be used in cosmetics and personal care products include Hydroxypropyl Guar, Guar Hydroxpropyltrimonium Chloride and Hydroxypropyl Guar Hydroxypropyltrimonium Chloride.


Among these guar ingredients, Guar Hydroxypropyltrimonium Chloride is most frequently used in cosmetic products.
Guar Hydroxypropyltrimonium Chloride is a water-soluble, organic compound that is a quaternary ammonium derivative of guar (aka cluster beans).
This means Guar Hydroxypropyltrimonium Chloride is a substance whose chemical structure has four carbon groups attached to a positively charged nitrogen atom.


While plant derived, there is a synthetic portion to Guar Hydroxypropyltrimonium Chloride.
Guar Hydroxypropyltrimonium Chloride is a quaternary ammonium derivative of guar gum.
Guar Hydroxypropyltrimonium Chloride is an antistatic, film forming, skin conditioning, viscosity controlling ingredient.


Guar Hydroxypropyltrimonium Chloride (GHPC) is a cationic surfactant that has been shown to be effective in the treatment of vaginal atrophy.
Guar Hydroxypropyltrimonium Chloride has been shown to be an excellent antimicrobial agent for the prevention and treatment of microbial infection.
Guar Hydroxypropyltrimonium Chloride is made of natural guar gum modified.


Guar Hydroxypropyltrimonium Chloride is a kind of cationic polymer, that provides excellent thickening and conditioning properties for hair and skin care products.
Guar Hydroxypropyltrimonium Chloride is derived from the seeds of guar plant scientifically known as chamois tetragonolobus, and it contains a high molecular weight sugar/ polysaccharide called as galactomannan.


Guar Hydroxypropyltrimonium Chloride comes as a yellowish powder, with characteristic but faint odor.
Guar Hydroxypropyltrimonium Chloride is a white or yellow fine powder derived from guar beans.
Guar Hydroxypropyltrimonium Chloride is a kind of galactomannan, which is a polysaccharide.


The guar bean comes from the guar plant, which is a legume. Major world suppliers include India, Pakistan, and the United States, as well as Australia and Africa.
The plant’s bean has a large endosperm, which is the part of the seed that acts as a food store for the developing plant.


Much of that endosperm contains galactomannan gum, which forms a viscous gel called guar gum when mixed with cold water.
Guar Hydroxypropyltrimonium Chloride is an organic compound with charged properties, derived from guar gum.
Guar (Cyamopsis tetragonoloba) is a domesticated legume crop, with most of of the world's production in India.


Cultivated plants grow to around 1 meter tall, with hairy stems and leaves.
The leaves, seed pods and seeds are all known to be edible, and are often cooked in curries.
Harvested seeds or 'guar beans' are dehusked, roasted, hydrated and ground to produce guar gum.


Guar Hydroxypropyltrimonium Chloride is generally considered safe.
Guar Hydroxypropyltrimonium Chloride can cause a mild allergic reaction in the form of irritated skin for some with sensitive skin.
This mostly depends on the amount used in the formula...Guar Hydroxypropyltrimonium Chloride should not exceed 1.0%.


Remember, the farther down the list of ingredients, the smaller the amount.
Guar Hydroxypropyltrimonium Chloride is a great conditioning agent for both skin and hair.
Guar Hydroxypropyltrimonium Chloride has charged properties that make it especially useful in hair care formulations.


Guar Hydroxypropyltrimonium Chloride is cationic (positively charged) and works by neutralizing the negative charges on hair strands that cause static and tangling.
Guar Hydroxypropyltrimonium Chloride is a quat (quaternary ammonium) synthetic derived from Guar gum.


Guar Hydroxypropyltrimonium Chloride acts as a conditioning agent for skin and hair, it also has antistatic properties.
Guar Hydroxypropyltrimonium Chloride is part of synthetic molecules, an exception in the COSMOS specifications: it is therefore authorized in organic.


Note that Guar Hydroxypropyltrimonium Chloride is obtained from the seed of a legume (Cyamopsis tetragonoloba).
Read "Guar Hydroxypropyltrimonium Chloride" on the ingredient list of your shampoo and you might get concerned, but actually, this ingredient with the scary name is actually very safe.


Guar Hydroxypropyltrimonium Chloride is a water-soluble, organic compound.
Guar Hydroxypropyltrimonium Chloride is plant derived from the guar (cluster bean) plant.
Although it is plant based, there is a synthetic portion to it.


Guar beans are harvested from the guar gum bush.
Guar Hydroxypropyltrimonium Chloride is grown in India and Pakistan.
In the U.S., Guar Hydroxypropyltrimonium Chloride is found in Texas.


Guar Hydroxypropyltrimonium Chloride is a naturally derived cationic polymer that is commonly used as a conditioning agent in shampoos, cream rinse conditioners, shower gels, body washes, and skin cleanser formulas.
Guar Hydroxypropyltrimonium Chloride is derived from the guar bean, the polymer's backbone is a Mannose-Galactose Polysaccharide that has been cauterized to enhance substantivity to hair and skin.


Guar Hydroxypropyltrimonium Chloride is a yellow, free-flowing powder with a slight amine odor.
Guar Hydroxypropyltrimonium Chloride is a yellow or white powdered ingredient that is obtained from guar beans.
Guar Hydroxypropyltrimonium Chloride is generally used in shampoos and other hair products where it acts as a conditioner and an anti-static agent.


Guar Hydroxypropyltrimonium Chloride is a plant-based ingredient that is extracted from guar beans.
Even though it is sourced from natural means, Guar Hydroxypropyltrimonium Chloride is still synthetic because of the way it is made.
After the extraction process is complete and a natural gum has been obtained from the guar beans, Guar Hydroxypropyltrimonium Chloride is then purified and filtered.


After this, the natural gum is reacted with epoxides to make Guar Hydroxypropyltrimonium Chloride.
Guar Hydroxypropyltrimonium Chloride is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
Guar Hydroxypropyltrimonium Chloride gives conditioning properties to shampoos and after-shampoo hair care products.


The effects of the cationic charge density, Guar Hydroxypropyltrimonium Chloride concentration in aqueous solution, and treatment time on bleached European hair have been studied.
A mechanical testing method has been successfully applied to determine the efficacy of cationic guars to improve the ease of combing.


The results were confirmed in a shampoo formulation on both virgin and bleached hair
Guar Hydroxypropyltrimonium Chloride is modified from Guar gum.
Add Guar Hydroxypropyltrimonium Chloride into cold water, stir until dispersed, add citric acid until pH<7, stir until thickened.



USES and APPLICATIONS of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
Guar Hydroxypropyltrimonium Chloride is commonly used as a conditioning agent in shampoo formulations with prominent anti-irritant, anti-inflammatory, and anti-static properties.
Additionally, Guar Hydroxypropyltrimonium Chloride also functions as a thickening agent in hair care formulations.


Guar Hydroxypropyltrimonium Chloride can observably enhance a formulation’s viscosity and stability.
Guar Hydroxypropyltrimonium Chloride is a cationic derivative of guar gum with excellent compatibility with anionic surfactant systems, which makes it a perfect choice for making 2-in-1 conditioning shampoos.


Guar Hydroxypropyltrimonium Chloride's positive-charged head bonds with the negative-charged hair keratin after being washed by anionic surfactants and form a 'free-breathing' thin film on hair and skin.
Such a film then provides protection and conditioning to our hair and skin.


The reason being is that it’s positively charged, also known as cationic.
This means that Guar Hydroxypropyltrimonium Chloride neutralises the negative charges on hair strands that cause hair to become static or tangled.
The result, easier combing, reduced frizz and minimised flyaways.


Guar Hydroxypropyltrimonium Chloride is also a lightweight ingredient as its often used in place of other anti-static ingredients that are heavier which weigh the hair down, which is especially an issue on finer hair.
Guar Hydroxypropyltrimonium Chloride has also been used as a detergent additive.


The hydroxyl group on Guar Hydroxypropyltrimonium Chloride interacts with fatty acids, causing it to form a complex with citric acid, which increases its effectiveness in reducing bacterial populations.
The citric acid-Guar Hydroxypropyltrimonium Chloride complex also inhibits the growth of gram-positive bacteria such as Staphylococcus and Streptococcus species.


Guar Hydroxypropyltrimonium Chloride may be used in bath products, hair conditioners, hair dyes, other hair care products and skin care products.
Guar Hydroxypropyltrimonium Chloride is a water-soluble derivative of natural guar gum and delivers conditioning properties to shampoos and after-shampoo hair care products.


Guar Hydroxypropyltrimonium Chloride is mainly used to give conditioning benefits to surfactant based formulations such as shampoos, body washes and shaving preparations.
Guar Hydroxypropyltrimonium Chloride is substantive to the hair where it has been proven to reduce tangling, improve hair feel, styling ability and gloss.


As this turns solutions cloudy Guar Hydroxypropyltrimonium Chloride is best suited for pearlescent or coloured formulations or emulsions.
A conditioning chemical added to hair products for easy detangling
Guar Hydroxypropyltrimonium Chloride is a water-soluble derivative of natural guar gum, and delivers conditioning properties to shampoos and after-shampoo hair care products.


Key applications of Guar Hydroxypropyltrimonium Chloride: Hair care, Shampoo, Personal care, Cosmetic products, Soaps and detergents, Beauty products, Industries, and Cosmetics
Guar Hydroxypropyltrimonium Chloride has also been used as a detergent additive.


The hydroxyl group on Guar Hydroxypropyltrimonium Chloride interacts with fatty acids, causing it to form a complex with citric acid, which increases its effectiveness in reducing bacterial populations.
The citric acid-Guar Hydroxypropyltrimonium Chloride complex also inhibits the growth of gram-positive bacteria such as Staphylococcus and Streptococcus species.


In personal care industry Guar Hydroxypropyltrimonium Chloride's usually used as conditioner, thickeners and stabilizers, also it's widely used in shampoo, shower gel, liquid soap, cream and other products since it has good compatibility in the formula.
Guar Hydroxypropyltrimonium Chloride is often used as an anti-static agent and skin or hair conditioner; it also increases viscosity.


Guar Hydroxypropyltrimonium Chloride is also found in hundreds of personal care products, such as shampoo, conditioner, dandruff treatments, styling products, soap, hairspray, and other products.
Guar Hydroxypropyltrimonium Chloride is used as a hair detangler.


Guar Hydroxypropyltrimonium Chloride is used to impart creaminess.
Guar Hydroxypropyltrimonium Chloride is thus added to dairy products.
Guar Hydroxypropyltrimonium Chloride also is used in place of ingredients that contain gluten.


The best known food in which this has occurred is certain breads.
Guar Hydroxypropyltrimonium Chloride is especially beneficial as a hair care product.
Because Guar Hydroxypropyltrimonium Chloride is positively charged, or cationic, it neutralizes the negative charges on hair strands that cause hair to become static or tangled.


Better yet, Guar Hydroxypropyltrimonium Chloride does this without weighing hair down.
With Guar Hydroxypropyltrimonium Chloride, you can have silky, non-static hair that retains its volume and provides a smoother brushing experience.
Guar Hydroxypropyltrimonium Chloride is a conditioning agent for all kind of hair care preparations.


Guar Hydroxypropyltrimonium Chloride can also be used in personal care products to thicken formulations and provide skin-conditioning benefits.
Guar Hydroxypropyltrimonium Chloride is a quaternary ammonium derivative of guar gum; used in hair conditioning products.
Typically used in formulations at 0.10% to 0.50% concentration levels, Guar Hydroxypropyltrimonium Chloride is entirely compatible with most common anionic, cationic, and amphoteric surfactants and is ideally suited for use in two-in-one conditioning shampoos and moisturizing skin cleansing products.


When used in personal cleansing formulations, Guar Hydroxypropyltrimonium Chloride imparts a soft, elegant after-feel to the skin.
Also, Guar Hydroxypropyltrimonium Chloride enhances wet comb and dry comb properties in shampoos and hair conditioning systems.
Unlike similar ingredients, Guar Hydroxypropyltrimonium Chloride is self-hydrating in water and does not require acidification during use.


Applications of Guar Hydroxypropyltrimonium Chloride: Two-in-one shampoos, Cream rinse conditioners, Styling gels and mousses
Facial cleansers, Shower gels and body washes, Liquid hand soaps, and Bar soaps
Guar Hydroxypropyltrimonium Chloride is commonly used as a conditioning agent in shampoo formulations.


Guar Hydroxypropyltrimonium Chloride forms a coacervate with anionic surfactants from the shampoo formulation upon dilution and deposits on the surface of hair providing conditioning in the form of reduced wet combing forces.
The dilution and deposition phenomenon occurs when the system is diluted below the critical micelle concentration of the shampoo surfactants, resulting in the formation of the insoluble coacervate.


The properties of the formed coacervate depend on a variety of characteristics of Guar Hydroxypropyltrimonium Chloride, including molecular weight and charge density, as well as the composition of surfactants and presence of electrolytes.
In addition, Guar Hydroxypropyltrimonium Chloride has reported uses in liquid soap and body wash formulations, hair conditioners, hair styling products, and skin care preparations.


Guar Hydroxypropyltrimonium Chloride has been widely used in Cosmetics & Toiletries industry with applications (such as being conditioner, viscosifier and flotation stabilizer, etc.) in translucent shampoo, body wash, facial cleanser, shaving gel.
Guar Hydroxypropyltrimonium Chloride is also used in skin care products where it deeply conditions the skin.


The chemical formula of Guar Hydroxypropyltrimonium Chloride is C6H16NO2.
Further, Guar Hydroxypropyltrimonium Chloride is used as a substitute for harsh silicones.
Applications include Hair care, Shampoo, Shower gel.



USE AND BENEFITS of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
Guar Hydroxypropyltrimonium Chloride is a large molecule, so it is used to provide a thickening effect in the formulation.
However,Guar Hydroxypropyltrimonium Chloride does not form a gel only to increase viscosity, which can be considered a special feature of it.
Another problem sometimes with thickeners is, they impair the foaming effect of surfactant, but in case of the guar gum, Guar Hydroxypropyltrimonium
Chloride enhances the foaming effect, that makes it an ideal choice for shampoos, handwashes, and body washes.
Also being a sugar molecule, Guar Hydroxypropyltrimonium Chloride can attract and hold water molecules, even when applied on skin or hair, which results in conditioning effect on dry hair and skin.

The guar gum is mostly available as quaternary ammonium salt- Guar Hydroxypropyltrimonium Chloride, which is a quite stable form of guar gum.
Guar Hydroxypropyltrimonium Chloride provides more conditioning effect that normal form of guar gum.
Guar Hydroxypropyltrimonium Chloride is used in lotions, creams, body washes, shampoos, conditioners, shower gels, etc.



APPLICATION AND CHARACTERISTICS of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
Guar Hydroxypropyltrimonium Chloride is a natural guar gum’s cationic replacement.
Guar Hydroxypropyltrimonium Chloride contributes excellent thickness and conditioning effect to hair care products and skin care products.
Guar Hydroxypropyltrimonium Chloride improves wet and dry combability and keep hair lubricity, soft, sparingly.

Guar Hydroxypropyltrimonium Chloride reduces stimulate of washings to skin and imparts slip and comfortable feeling.
Guar Hydroxypropyltrimonium Chloride is used with polyquaternium-7, polyquaternium-49(M-550,M-2001), its’ conditioning will be more excellent.
Guar Hydroxypropyltrimonium Chloride is mainly used in pearl shampoo, washing liquid, cream, liquid soap and care products.
When compound the solvent, disperse Guar Hydroxypropyltrimonium Chloride in the water on mix.

After Guar Hydroxypropyltrimonium Chloride dissolve in water the viscosity will be increasing slowly.
If use citric acid to revise pH to 6, Guar Hydroxypropyltrimonium Chloride’s viscosity will be increasing immediately.
The supposed concentration of Guar Hydroxypropyltrimonium Chloride is 0.2 – 0.5%.



WHAT IS GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE USED FOR?
The main function of Guar Hydroxypropyltrimonium Chloride is to extend conditioning properties to hair care products.
Guar Hydroxypropyltrimonium Chloride is also sometimes used in skin care products to achieve the same results.

*Hair care:
Guar Hydroxypropyltrimonium Chloride is a positively charged ingredient, that cancels the negative charge on hair causing it to have a static or become tangled.
Guar Hydroxypropyltrimonium Chloride makes the hair silky smooth without weighing them down

*Skin care:
Guar Hydroxypropyltrimonium Chloride nourishes the skin and also increases the viscosity of the formulations



WHY IS GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE USED?
Although a great conditioning agent for both skin and hair, Guar Hydroxypropyltrimonium Chloride is especially beneficial as a hair care product.
Because it is positively charged, or cationic, Guar Hydroxypropyltrimonium Chloride neutralizes the negative charges on hair strands that cause hair to become static or tangled.
Better yet, Guar Hydroxypropyltrimonium Chloride does this without weighing hair down.
With Guar Hydroxypropyltrimonium Chloride, you can have silky, non-static hair that retains its volume.



IS GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE A GOOD INGREDIENT FOR YOUR HAIR?
Guar Hydroxypropyltrimonium Chloride is cationic, meaning positively charged.
This makes Guar Hydroxypropyltrimonium Chloride an ideal ingredient to neutralize negative charges in your hair that leave it tangled or full of static.
Guar Hydroxypropyltrimonium Chloride is also effective at reducing frizz and adding moisture.
*For the Environment:
Guar Hydroxypropyltrimonium Chloride is biodegradable and has a very low tendency for bioaccumulation.



IS GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE NATURAL OR SYNTHETIC?
Guar Hydroxypropyltrimonium Chloride is sourced from the seeds of the guar plant, making it a natural ingredient and an organic compound.



FUNCTIONS of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE IN COSMETIC PRODUCTS:
ANTISTATIC:
Guar Hydroxypropyltrimonium Chloride reduces electrostatic charges (eg of the hair)

FILM FORMING:
Guar Hydroxypropyltrimonium Chloride produces a continuous film on skin, hair and / or nails

SKIN CONDITIONING:
Guar Hydroxypropyltrimonium Chloride maintains the skin in good condition

VISCOSITY CONTROLLING:
Guar Hydroxypropyltrimonium Chloride increases or decreases the viscosity of cosmetic products



WHAT DOES GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE DO IN A FORMULATION?
*Antistatic
*Hair conditioning
*Skin conditioning
*Viscosity controlling



SAFETY PROFILE of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
Guar Hydroxypropyltrimonium Chloride is very safe and has almost no side effects.
Guar Hydroxypropyltrimonium Chloride can cause minor irritation on highly sensitive skin.

Therefore, a patch test is recommended prior to use.
Other than this, there is no carcinogenicity or toxicity associated with Guar Hydroxypropyltrimonium Chloride.
Moreover, Guar Hydroxypropyltrimonium Chloride is biodegradable.



FUNCTIONS of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
• Antistatic
• Film forming
• Skin conditioning
• Viscosity controlling
• Conditioner
• Surfactant
• Emulsifier

Guar Hydroxypropyltrimonium Chloride is a water-soluble derivative of natural.
Is an organic compound, Guar Hydroxypropyltrimonium Chloride, that is a water-soluble quaternary ammonium derivative of guar gum.
Guar Hydroxypropyltrimonium Chloride gives conditioning properties to shampoos and after-shampoo hair care products.

*Antistatic :
Guar Hydroxypropyltrimonium Chloride reduces static electricity by neutralizing electrical charge on a surface

*Film forming :
Guar Hydroxypropyltrimonium Chloride produces a continuous film on skin, hair or nails

*Skin conditioning :
Guar Hydroxypropyltrimonium Chloride maintains skin in good condition

*Viscosity controlling :
Guar Hydroxypropyltrimonium Chloride increases or decreases the viscosity of cosmetics



HOW GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE IS MADE?
Guar Hydroxypropyltrimonium Chloride production starts by milling guar beans to obtain the natural gum.
Guar Hydroxypropyltrimonium Chloride is then purified, filtered, and reacted with epoxides.
One method involves converting guar with 3-chloro-2 hystroxyproply trimethyl ammonium chloride.



PROPERTIES of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
Guar Hydroxypropyltrimonium Chloride is a biopolymer.
Therefore, many of Guar Hydroxypropyltrimonium Chloride's properties will depend on its molecular weight and charge density, which is subject to the degree of cationic substition.

Guar Hydroxypropyltrimonium Chloride is soluble in water.
Guar Hydroxypropyltrimonium Chloride is insoluble in alcohol and oils.
The melting point of Guar Hydroxypropyltrimonium Chloride is 170 ˚C.



BENEFITS of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
*Yields nice viscous qualities
*Great conditioning agent
*Easier wet & dry combing
*Smoother brushing experience
*Natural guar gum origin
*Antistatic
*Detangles hair
*conditioning
*This cationic polymer, Guar Hydroxypropyltrimonium Chloride, is substantive to the hair where it improves wet and dry combability.
Guar Hydroxypropyltrimonium Chloride is compatible with anionic, nonionic and cationic surfactants and is suitable for cold processing.



WHAT ARE THE BENEFITS of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE FOR THE SKIN OR HAIR?
*Enhanced ease of wet hair combing
*Enhanced comfort of dry hair combing
*Improved hair manageability
*Improved foam quality, stability, and texture
*Increased active delivery of silicone
*Impart soft, elegant after-feel to the skin from personal cleansing formulations



WHAT IS THE DIFFERENCE BETWEEN GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE AND GUAR GUM?
When it comes to Guar Hydroxypropyltrimonium Chloride vs guar gum, the former is a derived form of guar gum.
While also sourced from the guar plant, guar gum is a polysaccharide, while Guar Hydroxypropyltrimonium Chloride is a chloride.



FEATURES AND BENEFITS of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
*Low plant protein residues.
*Uniformity of substitution degree, low content of water insoluble matter.
*Low impurity content.
*Low residual etherifier content.
*High purity, good light transmittance, high tonality.



PHYSICAL and CHEMICAL PROPERTIES of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
Melting Point: >300°C
Solubility: Soluble in water
Viscosity: High
Molecular Formula: C6H16NO2.xCl.xUnspecified
Density: 1.3 g/mL at 25 °C(lit.)
Appearance: Yellow powder
Concentration: 0.2-1%
Important Criteria: palm oil-free
vegan
animal non testing
Non GMO
Induction: Water phase
International Nomenclature Of Cosmetic Ingredients: Hydroxypropyl Guar, Hydroxypropyltrimonium Chloride
Original Material: Guar gum
pH: 9-11
Scent Smell: Characteristic
Appearance: Slight yellow powder
Odor: minor characteristic odor
pH(1% aq): 8.0-11.0
“N”content(%): 1.3-1.7
Loss on drying (%): ≤13
Ash(%): ≤3
Dispersion in water: Good dispersibility in water



FIRST AID MEASURES of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
-Description of first-aid measures:
*After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.



ACCIDENTAL RELEASE MEASURES of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
-Environmental precautions:
No special precautionary measures necessary.
-Methods and materials for containment and cleaning up:
Observe possible material restrictions.
Take up with liquidabsorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
-Extinguishing media:
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.



EXPOSURE CONTROLS/PERSONAL PROTECTION of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
not required
*Respiratory protection:
Not required.
-Control of environmental exposure:
No special precautionary measures necessary.



HANDLING and STORAGE of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
Keratrix
Aquacat CG518
Aquacat IC
Aquacat PF618
N-Hance 3000 Cationic Guar
N-Hance 3196 Cationic Guar
COSMEDIA Guar C 261
COSMEDIA Guar C 261 N
DEHYQUART Guar HP
DEHYQUART Guar N
DEHYQUART Guar TC
Dermatein Power Powder IV - Lustre
COSMOROL GQ6
Fibroforce
GoBlond
Seridefrizz Intense Salon
Seriseal
Seriseal DS
DOWSIL CE 2060 Emulsion
ECOPOL -13
ECOPOL -13S
ECOPOL -14
ECOPOL -14S
ECOPOL -17
ACEROMINE
ROSAMINE
Hony 103
GUAR 13S
GUAR 14S
Guangzhou Tinci Materials Technology (Tinci)
GUAR 15S
Activsoft C-14
Activsoft C-17
Finsoft C-13
Finsoft C-14
Finsoft C-17
Guarsafe® JK-110
Guarsafe® JK-110H
Guarsafe® JK-130
Guarsafe® JK-140
Guarsafe® JK-141
SI6037Z (D)
SI6400Z (D)
SeraShine® EM 503
SeraShine® EM 504
Vida-Care GHTC 03
KY-286
KY-286-N
KY-286-S
Kiyu New Material
KY-386
KY-386-N
Cesmetic DP 101
• Conditioning Agents
Cesmetic DP 105
Cesmetic DP 109
Esaflor BF 2
Esaflor BF 7
Esaflor EC 3
Esaflor EC 4
Catcol® Guar Hydroxypropyltrimonium chloride hydroxypropyl
Catcol® Guar hydroxypropyltrimonium chloride
MICONIUM CG-L200
MICONIUM CG-L45
MICONIUM CG-M35N
Armocare® G113
Armocare® G114
POLYCOS CA-3000
POLYCOS CA-3001
POLYCOS CA-3002
POLYCOS CA-3003
POLYCOS CA-3004
Resoft 14S
SMAGUAR CAT-110
SMAGUAR CAT-130
SMAGUAR CAT-140
SMAGUAR CAT-170
SMAGUAR SUPREME
Hi-Care® 1000
Jaguar® C-1000
Jaguar® C-13-S
Jaguar® C-14-S
Jaguar® C-17
SC-14-S Cationic Guar Gum
SUNCOS-CG 2018D
SUNCOS-CG 3015D
SUNCOS-CG 3515
SUNCOS-CG 3515D
SUNCOS-CG 520D
GuarSilk™
Thorcoquat 12S
Thorcoquat 13S
Thorcoquat 14S
Thorcoquat 15S
Cationic Guar
C-130
C-140(LPH)
SYNERGUAR SN-1410
GUM GUAR 2-HYDROXY-3-(TRIMETHYLAMMONIO)&
cosmediaguarc261
Guar,2-hydroxy-3-trimethylammoniopropylether,chloride
Guargum,etherwith3-chloro-2-hydroxypropyltrimethylammoniumchloride
gumguar2-hydroxy-3-(trimethylammonio)-propylet
jaguarc13s
jaguarc14s
jaguar
Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride
Guar Gum, 2-Hydroxypropyl 2-Hydroxy-3-(Trimethylammonio)Propyl Ether Chloride
Guar, 2-hydroxy-3-trimethylammoniopropyl ether, chloride
Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride
Cationic Guar Gum
Guar Hydroxypropyltrimonium Chloride
Guar gum, 2-Hydroxy-3-(trimethylammonio)propyl Ether, Chloride
Guar Hyd Prop Trimonium Chlor
Guar Hydroxy Propyl Trimonium Chloride
T/N: Esaflor EC4
Trimethylammoniopropyl Guar Chloride 100%
Unguar C461

GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
Guar Hydroxypropyltrimonium Chloride is an organic compound
Guar Hydroxypropyltrimonium Chloride is a water-soluble quaternary ammonium derivative of guar gum.
Guar Hydroxypropyltrimonium Chloride gives conditioning properties to shampoos and after-shampoo hair care products.


CAS NUMBER: 65497-29-2

EC NUMBER: 613-809-4

MOLECULAR FORMULA: C6H16NO2.

MOLECULAR WEIGHT: 652.03 g/mol

IUPAC NAME: Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride.


Guar Hydroxypropyltrimonium Chloride is a quaternary ammonium derivative of guar gum
Guar Hydroxypropyltrimonium Chloride used in hair conditioning products.
Guar Hydroxypropyltrimonium Chloride is a white or yellow fine powder derived from guar beans.

Guar Hydroxypropyltrimonium Chloride is a kind of galactomannan, which is a polysaccharide.
The guar bean comes from the guar plant, which is a legume.

The plant's bean has a large endosperm, which is the part of the seed that acts as a food store for the developing plant.
Much of that endosperm contains galactomannan gum, which forms a viscous gel called guar gum when mixed with cold water

Guar Hydroxypropyltrimonium Chloride is often used as an anti-static agent and skin or hair conditioner
Guar Hydroxypropyltrimonium Chloride also increases viscosity.

Guar Hydroxypropyltrimonium Chloride is also found in hundreds of personal care products, such as shampoo, conditioner, dandruff treatments, styling products, soap, hairspray, and other products.
Guar Hydroxypropyltrimonium Chloride is used as a hair detangler.

How Guar Hydroxypropyltrimonium Chloride Is Made?
Guar Hydroxypropyltrimonium Chloride production starts by milling guar beans to obtain the natural gum.
That gum is then purified, filtered, and reacted with epoxides.
One method involves converting guar with 3-chloro-2 hystroxyproply trimethyl ammonium chloride.

Guar Hydroxypropyltrimonium Chloride is deemed safe to use in cosmetics and personal care products at a maximum concentration of 0.05%.
Guar Hydroxypropyltrimonium Chloride is biodegradable and has a very low tendency for bioaccumulation.

Is Guar Hydroxypropyltrimonium Chloride natural or synthetic?
Guar Hydroxypropyltrimonium Chloride is sourced from the seeds of the guar plant, making it a natural ingredient and an organic compound.

What's the difference between Guar Hydroxypropyltrimonium Chloride and guar gum?
When it comes to Guar Hydroxypropyltrimonium Chloride vs guar gum, the former is a derived form of guar gum.
While also sourced from the guar plant, guar gum is a polysaccharide, while Guar Hydroxypropyltrimonium Chloride is a chloride.

Is Guar Hydroxypropyltrimonium Chloride a good ingredient for your hair?
Guar Hydroxypropyltrimonium Chloride is cationic, meaning positively charged.
This makes it an ideal ingredient to neutralize negative charges in your hair that leave it tangled or full of static.
Guar Hydroxypropyltrimonium Chloride is also effective at reducing frizz and adding moisture.

Guar Hydroxypropyltrimonium Chloride is a water-soluble
Guar Hydroxypropyltrimonium Chloride is an organic compound

Guar Hydroxypropyltrimonium Chloride is a quaternary ammonium derivative of guar (aka cluster beans).
This means it is a substance whose chemical structure has four carbon groups attached to a positively charged nitrogen atom.
While plant derived, there is a synthetic portion to it.

Why is Guar Hydroxypropyltrimonium Chloride used?
Although a great conditioning agent for both skin and hair, Guar Hydroxypropyltrimonium Chloride is especially beneficial as a hair care product.
Because it is positively charged, or cationic, it neutralizes the negative charges on hair strands that cause hair to become static or tangled.
Better yet, it does this without weighing hair down.
With this ingredient, you can have silky, non-static hair that retains its volume.

Guar Hydroxypropyltrimonium Chloride is a yellow or white powdered ingredient
Guar Hydroxypropyltrimonium Chloride is obtained from guar beans.

Guar Hydroxypropyltrimonium Chloride is generally used in shampoos and other hair products where it acts as a conditioner and an anti-static agent.
Guar Hydroxypropyltrimonium Chloride is also used in skin care products where it deeply conditions the skin.

The chemical formula of Guar Hydroxypropyltrimonium Chloride is C6H16NO2.
Further, it is used as a substitute for harsh silicones.

What is Guar Hydroxypropyltrimonium Chloride used for?
The main function of Guar Hydroxypropyltrimonium Chloride is to extend conditioning properties to hair care products.
Guar Hydroxypropyltrimonium Chloride is also sometimes used in skin care products to achieve the same results.

*Hair care: Guar Hydroxypropyltrimonium Chloride is a positively charged ingredient, that cancels the negative charge on hair causing it to have a static or become tangled.
This ingredient makes the hair silky smooth without weighing them down

*Skin care: Guar Hydroxypropyltrimonium Chloride nourishes the skin and also increases the viscosity of the formulations

Guar Hydroxypropyltrimonium Chloride is a plant-based ingredient that is extracted from guar beans.
Even though it is sourced from natural means, it is still synthetic because of the way it is made.

After the extraction process is complete and a natural gum has been obtained from the guar beans, it is then purified and filtered.
After this, the natural gum is reacted with epoxides to make Guar Hydroxypropyltrimonium Chloride.

What does Guar Hydroxypropyltrimonium Chloride do in a formulation?
-Antistatic effect
-Hair conditioning
-Skin conditioning
-Viscosity controlling

Guar Hydroxypropyltrimonium Chloride is commonly used as a conditioning agent in shampoo formulations.
Guar Hydroxypropyltrimonium Chloride forms a coacervate with anionic surfactants from the shampoo formulation upon dilution and deposits on the surface of hair providing conditioning in the form of reduced wet combing forces.
The dilution and deposition phenomenon occurs when the system is diluted below the critical micelle concentration of the shampoo surfactants, resulting in the formation of the insoluble coacervate.
The properties of the formed coacervate depend on a variety of characteristics of the polymer, including molecular weight and charge density, as well as the composition of surfactants and presence of electrolytes.
In addition, Guar Hydroxypropyltrimonium Chloride is used in liquid soap and body wash formulations, hair conditioners, hair styling products, and skin care preparations

Hydroxypropyl Guar Hydroxypropyltrimonium Chloride is an organic compound with charged properties, derived from guar gum.
Guar (Cyamopsis tetragonoloba) is a domesticated legume crop, with most of of the world's production in India.
Cultivated plants grow to around 1 meter tall, with hairy stems and leaves.
The leaves, seed pods and seeds are all known to be edible, and are often cooked in curries.
Harvested seeds or 'guar beans' are dehusked, roasted, hydrated and ground to produce guar gum.

Hydroxypropyl Guar Hydroxypropyltrimonium Chloride has charged properties that make it especially useful in hair care formulations.
Guar Hydroxypropyltrimonium Chloride is cationic (positively charged) and works by neutralizing the negative charges on hair strands that cause static and tangling.
This ingredient can also be used in personal care products to thicken formulations and provide skin-conditioning benefits.

Guar Hydroxypropyltrimonium Chloride is a water-soluble, organic compound.
Guar Hydroxypropyltrimonium Chloride is plant derived from the guar (cluster bean) plant.

Although Guar Hydroxypropyltrimonium Chloride is plant based, there is a synthetic portion to it.
Guar beans are harvested from the guar gum bush.

Guar Hydroxypropyltrimonium Chloride is grown in India and Pakistan
Guar Hydroxypropyltrimonium Chloride is used to impart creaminess.

They are thus added to dairy products.
They also are used in place of ingredients that contain gluten.
The best known food in which this has occurred is certain breads.

Guar Hydroxypropyltrimonium Chloride is a great conditioning agent for both skin and hair.
Guar Hydroxypropyltrimonium Chloride is especially beneficial as a hair care product.

Because Guar Hydroxypropyltrimonium Chloride is positively charged, or cationic, it neutralizes the negative charges on hair strands that cause hair to become static or tangled. Better yet, it does this without weighing hair down.
Guar Hydroxypropyltrimonium Chloride is generally considered safe.

Guar Hydroxypropyltrimonium Chloride is a conditioning ingredient that is used in both skincare and hair care products.
Guar Hydroxypropyltrimonium Chloride is a water-soluble ingredient that is derived from plant-based sources.
Guar Hydroxypropyltrimonium Chloride is generally used in hair care products as it helps to reduce static while retaining volume.

Why Is Guar Hydroxypropyltrimonium Chloride Used For?
Guar Hydroxypropyltrimonium Chloride is a conditioning agent for both the skin and hair which means that it helps to moisturize.
While Guar Hydroxypropyltrimonium Chloride is sometimes used in skincare formulations it is more often used in hair care products.

Guar Hydroxypropyltrimonium Chloride is most widely used in hair care products due to the added benefit of helping to reduce static between hair strands.
This helps to reduce frizz and minimize flyaways.
Guar Hydroxypropyltrimonium Chloride does this through its positive charge, neutralizing the negative charges on the hair that cause static.
Guar Hydroxypropyltrimonium Chloride is also a lightweight ingredient as is often used in place of other anti-static ingredients that are heavier, weighing the hair down.

APPLICATION AND CHARACTERISTICS
*Guar Hydroxypropyltrimonium Chloride is a natural guar gum's cationic replacement.
*Guar Hydroxypropyltrimonium Chloride contributes excellent thickness and conditioning effect to hair care products and skin care products.
*Guar Hydroxypropyltrimonium Chloride improves wet and dry combability and keep hair lubricity, soft, springly
*Guar Hydroxypropyltrimonium Chloride reduces stimulate of washings to skin
*Guar Hydroxypropyltrimonium Chloride imparts slip and comfortable feeling.
*Guar Hydroxypropyltrimonium Chloride is used with polyquaternium-7, polyquaternium-49(M-550,M-2001), it's conditioning will be more excellent.
*Guar Hydroxypropyltrimonium Chloride mainly used in pearl shampoo, washing liquid, cream, liquid soap and care products.
*When compound the solvent, disperse it in the water on mix.
*After it dissolve in water the viscosity will be increasing slowly.
*If use actric acid to revise pH to 6, the solvent's viscosity will be increasing immediately.
*The supposed concentration is 0.2 – 0.5%

Guar Hydroxypropyltrimonium Chloride is a naturally derived cationic polymer that is commonly used as a conditioning agent in shampoos, cream rinse conditioners, shower gels, body washes, and skin cleanser formulas.
Derived from the guar bean, the polymer's backbone is a Mannose-Galactose Polysaccharide that has been cauterized to enhance substantivity to hair and skin.
Guar Hydroxypropyltrimonium Chloride is a yellow, free-flowing powder
Guar Hydroxypropyltrimonium Chloride has a slight amine odor.

Guar Hdyroxypropyltrimonium Chloride is generally used in hair care products as it helps to reduce static while retaining volume.
Guar Hdyroxypropyltrimonium Chloride is most widely used in hair care products
Guar Hdyroxypropyltrimonium Chloride is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum

Typically used in formulations at 0.10% to 0.50% concentration levels, Guar Hydroxypropyltrimonium Chloride is entirely compatible with most common anionic, cationic, and amphoteric surfactants
Guar Hydroxypropyltrimonium Chloride is ideally suited for use in two-in-one conditioning shampoos and moisturizing skin cleansing products.

When used in personal cleansing formulations, Guar Hydroxypropyltrimonium Chloride imparts a soft, elegant after-feel to the skin.
Also, it enhances wet comb and dry comb properties in shampoos and hair conditioning systems.
Unlike similar ingredients, Guar Hydroxypropyltrimonium Chloride is self-hydrating in water and does not require acidification during use.

Applications
*Two-in-one shampoos
*Cream rinse conditioners
*Styling gels and mousses
*Facial cleansers
*Shower gels and body washes
*Liquid hand soaps
*Bar soaps

What are the benefits of Guar Hydroxypropyltrimonium Chloride for the skin or hair?
Guar Hydroxypropyltrimonium Chloride enhances ease of wet hair combing
Guar Hydroxypropyltrimonium Chloride enhances comfort of dry hair combing
Guar Hydroxypropyltrimonium Chloride improves hair manageability
Guar Hydroxypropyltrimonium Chloride improves foam quality, stability, and texture
Guar Hydroxypropyltrimonium Chloride increases active delivery of silicone
Guar Hydroxypropyltrimonium Chloride imparts soft, elegant after-feel to the skin from personal cleansing formulations

Extraction: Guar Hydroxypropyltrimonium Chloride is a derivative of guar seeds.
Guar Hydroxypropyltrimonium Chloride is a type of galactomannan, a polysaccharide, which forms a viscous gel called guar gum when mixed with cold water.

Benefits: Often used as an antistatic and conditioning agent for hair or skin
Guar Hydroxypropyltrimonium Chloride also increases the viscosity of cosmetics.

Guar gum is derived from the seeds of guar plant scientifically known as chamois tetragonolobus, and it contains a high molecular weight sugar/ polysaccharide called as galactomannan.
Guar Hydroxypropyltrimonium Chloride comes as a yellowish powder, with characteristic but faint odor.


GENERAL PROPERTIES:

*Melting Point: >300°C

*Solubility: Soluble in water

*Viscosity: High

*Flash Point: 93.3°C

*Physical Description: Colorless to Yellow Powder

*Color: Yellow

*Form: Solid

*Density: 1.3 g/mL

*Odour: Odorless


Guar Hdyroxypropyltrimonium Chloride is a white or yellow fine powder derived from guar beans.
Guar Hdyroxypropyltrimonium Chloride is a water-soluble
Guar Hdyroxypropyltrimonium Chloride is organic compound

Guar Hdyroxypropyltrimonium Chloride is a quaternary ammonium derivative of guar
Guar Hdyroxypropyltrimonium Chloride is used in hair conditioning products.
Guar Hdyroxypropyltrimonium Chloride is commonly used as a conditioning agent in shampoo formulations.

Use & Benefits:
The galactomannan is a large molecule, so it is used to provide a thickening effect in the formulation.
However, it does not form a gel only to increase viscosity, which can be considered a special feature of it.
Another problem sometimes with thickeners is, they impair the foaming effect of surfactant, but in case of the guar gum, it enhances the foaming effect, that makes it an ideal choice for shampoos, handwashes, and body washes.
Also being a sugar molecule, it can attract and hold water molecules, even when applied on skin or hair, which results in conditioning effect on dry hair and skin.

The guar gum is mostly available as quaternary ammonium salt- Guar Hydroxypropyltrimonium Chloride, which is a quite stable form of guar gum.
Guar Hydroxypropyltrimonium Chloride provides more conditioning effect that normal form of guar gum.
Guar Hydroxypropyltrimonium Chloride is used in lotions, creams, body washes, shampoos, conditioners, shower gels, etc.

Guar Hydroxypropyltrimonium Chloride is a resinous material made from the guar bean.
Guar Gum is a type of polysaccharide called galactomannan made from legume plants that consists of a polymannose backbone to which galactose groups are bound.
Derivatives of Guar Gum that also may be used in cosmetics and personal care products include Hydroxypropyl Guar, Guar Hydroxpropyltrimonium Chloride and Hydroxypropyl Guar Hydroxypropyltrimonium Chloride.
Among these guar ingredients, Guar Hydroxypropyltrimonium Chloride is most frequently used in cosmetic products.
Guar Hydroxypropyltrimonium Chloride may be used in bath products, hair conditioners, hair dyes, other hair care products and skin care products.

Guar Hydroxypropyltrimonium Chloride is a water-soluble derivative of natural guar gum
Guar Hydroxypropyltrimonium Chloride delivers conditioning properties to shampoos and after-shampoo hair care products.
Guar Hdyroxypropyltrimonium Chloride is a white or yellow fine powder derived from guar beans.

Guar Hdyroxypropyltrimonium Chloride is a kind of galactomannan, which is a polysaccharide
Guar Hdyroxypropyltrimonium Chloride is often used as an anti-static agent and hair or skin conditioner
Guar Hydroxypropyltrimonium Chloride also increases viscosity.
Guar Hdyroxypropyltrimonium Chloride is also found in hundreds of personal care products, such as shampoo, conditioner, dandruff treatments, styling products, soap, hairspray, and other products.

Guar Hydroxypropyltrimonium Chloride is a water-soluble derivative of natural guar gum
Guar Hydroxypropyltrimonium Chloride (GHPT) is anti-inflammatory that is also used as a thickening, conditioning, and anti-static agent.
Guar Hydroxypropyltrimonium Chloride helps maintain a product's smoothing action.

Some manufacturers cite it as also having skin-softening capabilities.
Guar Hydroxypropyltrimonium Chloride imparts excellent skin conditioning in creams or lotions that otherwise may not be used on the face.

Guar Hydroxypropyltrimonium Chloride adds lubricity to a product when in contact with the skin.
There is some evidence that it can enhance a formulation's viscosity and stability.
Guar Hydroxypropyltrimonium Chloride is a derivative of guar gum.

Guar Hydroxypropyltrimonium Chloride is a quaternary ammonium derivative of guar gum
Guar Hydroxypropyltrimonium Chloride is a white or yellow fine powder derived from guar beans.
Guar Hydroxypropyltrimonium Chloride is used as a hair detangler.

Guar Hydroxypropyltrimonium Chloride is biodegradable
Guar Hydroxypropyltrimonium Chloride is a water-soluble

Guar Hydroxypropyltrimonium Chloride is a yellow or white powdered ingredient
Guar Hydroxypropyltrimonium Chloride is obtained from guar beans.
Guar Hydroxypropyltrimonium Chloride is used as a substitute for harsh silicones.

Guar Hydroxypropyltrimonium Chloride nourishes the skin and also increases the viscosity of the formulations
Guar Hydroxypropyltrimonium Chloride is a water-soluble, organic compound.

Guar Hydroxypropyltrimonium Chloride is plant derived from the guar (cluster bean) plant.
Guar Hydroxypropyltrimonium Chloride is used to impart creaminess.
Guar Hydroxypropyltrimonium Chloride helps to reduce static while retaining volume.

Guar Hydroxypropyltrimonium Chloride improves wet and dry combability and keep hair lubricity, soft, springly
Guar Hydroxypropyltrimonium Chloride mainly used in pearl shampoo, washing liquid, cream, liquid soap and care products.

Guar Hydroxypropyltrimonium Chloride has a slight amine odor.
Guar Hdyroxypropyltrimonium Chloride is an organic compound

Guar Hydroxypropyltrimonium Chloride is a water-soluble quaternary ammonium derivative of guar gum
Guar Hydroxypropyltrimonium Chloride improves foam quality, stability, and texture
Guar Hydroxypropyltrimonium Chloride increases active delivery of silicone


SYNONYMS:

Guar Hydroxypropyltrimonium Chloride
Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride
B16G315W7A
65497-29-2
UNII-B16G315W7A
Jaguar C 14S
Jaguar C 15
Jaguar C 17
Guar Hydroxypropyltrimonium Chloride
Cosmedia Guar C 261
Guar gum, ether with 3-chloro-2-hydroxypropyltrimethylammonium chloride
Guar, 2-hydroxy-3-trimethylammoniopropyl ether, chloride
Jaguar C 13S
Cationic Guar Gum
aquacat
aquacat clear cationic solution
cosmedia guar C 261
guar gum, ether with 3-chloro-2-hydroxypropyltrimethylammonium chloride
Guar Hydroxypropyltrimonium Chloride
guar, 2-hydroxy-3-trimethylammoniopropyl ether, chloride
jaguar C 17
N-hance cationic guar
jaguarc15
jaguarc17
jaguarc14s
jaguarc13s
cosmediaguarc261
Guar Hydroxypropyl Trimoniun Chloride
2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER CHLORIDE GUAR GUM
CHLORIDE GUAR GUM, 2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER
GUAR GUM, 2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER, CHLORIDE
GUAR GUM, 2HYDROXY3(TRIMETHYLAMMONIO)PROPYL ETHER, CHLORIDE
GUAR GUM, ETHER WITH 3-CHLORO-2-HYDROXYPROPYLTRIMETHYLAMMONIUM CHLORIDE; GUAR, 2-HYDROXY-3-TRIMETHYLAMMONIOPROPYL ETHER, CHLORIDE
GUAR HYDROPROPYLTRIMONIUM CHLORIDE
Guar Hydroxypropyltrimonium Chloride
O-[2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL] GUAR GUM CHLORIDE
guar gum, 2-hydroxypropyl 2-hydroxy-3-(trimethylammonio)propyl ether, chloride
guarquat CP 500KC
jaguar C 16
Guar Hydroxypropyltrimonium Chloride
Cosmedia Guar C 261
Guar gum, ether with 3-chloro-2-hydroxypropyltrimethylammonium chloride
Guar, 2-hydroxy-3-trimethylammoniopropyl ether, chloride
Jaguar C 13S
Cationic Guar Gum

GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
Guar hydroxypropyltrimonium chloride is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
Guar hydroxypropyltrimonium chloride gives conditioning properties to shampoos and after-shampoo hair care products.
The effects of the cationic charge density, guar concentration in aqueous solution, and treatment time on bleached European hair have been studied.

CAS: 65497-29-2
MF: C6H16NO2.xCl.xUnspecified

A mechanical testing method has been successfully applied to determine the efficacy of cationic guars to improve the ease of combing.
The results were confirmed in a shampoo formulation on both virgin and bleached hair.
Guar hydroxypropyltrimonium chloride is a white or yellow fine powder derived from guar beans.
Guar hydroxypropyltrimonium chloride is a kind of galactomannan, which is a polysaccharide.
The guar bean comes from the guar plant, which is a legume.
Major world suppliers include India, Pakistan, and the United States, as well as Australia and Africa.

The plant’s bean has a large endosperm, which is the part of the seed that acts as a food store for the developing plant.
Much of that endosperm contains galactomannan gum, which forms a viscous gel called guar gum when mixed with cold water.
Guar hydroxypropyltrimonium chloride is a yellow or white powdered ingredient that is obtained from guar beans.
Guar hydroxypropyltrimonium chloride is generally used in shampoos and other hair products where it acts as a conditioner and an anti-static agent.
Guar hydroxypropyltrimonium chloride is also used in skin care products where it deeply conditions the skin.
The chemical formula of Guar hydroxypropyltrimonium chloride is C6H16NO2.
Further, Guar hydroxypropyltrimonium chloride is used as a substitute for harsh silicones.

Guar hydroxypropyltrimonium chloride is a conditioning ingredient that is used in both skincare and hair care products.
Guar hydroxypropyltrimonium chloride is a water-soluble ingredient that is derived from plant-based sources.
Guar hydroxypropyltrimonium chloride is generally used in hair care products as it helps to reduce static while retaining volume.
Guar Hydroxypropyltrimonium Chloride is a compound that is water soluble.
Although a great conditioning agent for both hair and scalp, this compound most definitely gives the biggest benefits to your strands of hair.
The reason being is that Guar hydroxypropyltrimonium chloride’s positively charged, also known as cationic.
This means that Guar hydroxypropyltrimonium chloride neutralises the negative charges on hair strands that cause hair to become static or tangled.

The result, easier combing, reduced frizz and minimised flyaways.
Guar Hydroxypropyltrimonium Chloride is also a lightweight ingredient as its often used in place of other anti-static ingredients that are heavier which weigh the hair down, which is especially an issue on finer hair.
Although Guar hydroxypropyltrimonium chloride’s majority plant based, there is a synthetic portion to the ingredient.
Guar beans are harvested from the Guar Gum Bush.
This bush can be found in the likes of India and Pakistan,USA and even Australia and Africa.
Guar hydroxypropyltrimonium chloride is identified as a white or yellow like powder.
With this ingredient you can get non-static silky hair.
Guar hydroxypropyltrimonium chloride also helps it retain volume and makes it easier to manage.
So basically Guar hydroxypropyltrimonium chloride is amazing for your hair.

Guar hydroxypropyltrimonium chloride (GHPC) is a cationic surfactant that has been shown to be effective in the treatment of vaginal atrophy.
Guar hydroxypropyltrimonium chloride has been shown to be an excellent antimicrobial agent for the prevention and treatment of microbial infection.
Guar hydroxypropyltrimonium chloride has also been used as a detergent additive.
The hydroxyl group on Guar hydroxypropyltrimonium chloride interacts with fatty acids, causing Guar hydroxypropyltrimonium chloride to form a complex with citric acid, which increases its effectiveness in reducing bacterial populations.
The citric acid-GHPC complex also inhibits the growth of gram-positive bacteria such as Staphylococcus and Streptococcus species.

Guar hydroxypropyltrimonium chloride Chemical Properties
Melting point: >300°C(lit.)
Density: 1.3 g/mL at 25 °C(lit.)
Odor: 100.00?%. odorless
EPA Substance Registry System: Guar hydroxypropyltrimonium chloride (65497-29-2)

Uses
Guar hydroxypropyltrimonium chloride is an anti-irritant and anti-inflammatory that is also used as a thickening, conditioning, and anti-static agent.
Guar hydroxypropyltrimonium chloride helps maintain a product’s smoothing action.
Some manufacturers cite Guar hydroxypropyltrimonium chloride as also having skin-softening capabilities.
Guar hydroxypropyltrimonium chloride imparts excellent skin conditioning in creams or lotions that otherwise may not be used on the face.
Guar hydroxypropyltrimonium chloride adds lubricity to a product when in contact with the skin.
There is some evidence that Guar hydroxypropyltrimonium chloride can enhance a formulation’s viscosity and stability.
Guar hydroxypropyltrimonium chloride is a derivative of guar gum.

Guar hydroxypropyltrimonium chloride is often used as an anti-static agent and skin or hair conditioner; it also increases viscosity.
Guar hydroxypropyltrimonium chloride is also found in hundreds of personal care products, such as shampoo, conditioner, dandruff treatments, styling products, soap, hairspray, and other products.

Guar hydroxypropyltrimonium chloride production starts by milling guar beans to obtain the natural gum.
That gum is then purified, filtered, and reacted with epoxides.
One method involves converting guar with 3-chloro-2 hystroxyproply trimethyl ammonium chloride.

Although a great conditioning agent for both skin and hair, guar hydroxypropyltrimonium chloride is especially beneficial as a hair care product.
Because Guar hydroxypropyltrimonium chloride is positively charged, or cationic, it neutralizes the negative charges on hair strands that cause hair to become static or tangled.
Better yet, Guar hydroxypropyltrimonium chloride does this without weighing hair down.
With Guar hydroxypropyltrimonium chloride, you can have silky, non-static hair that retains its volume.

Guar hydroxypropyltrimonium chloride is a conditioning agent for both the skin and hair which means that Guar hydroxypropyltrimonium chloride helps to moisturize.
While guar hydroxypropyltrimonium chloride is sometimes used in skincare formulations it is more often used in hair care products.

Guar hydroxypropyltrimonium chloride is most widely used in hair care products due to the added benefit of helping to reduce static between hair strands.
Guar hydroxypropyltrimonium chloride helps to reduce frizz and minimize flyaways.
Guar hydroxypropyltrimonium chloride does this through its positive charge, neutralizing the negative charges on the hair that cause static.
Guar hydroxypropyltrimonium chloride is also a lightweight ingredient as is often used in place of other anti-static ingredients that are heavier, weighing the hair down.

Synonyms
Guar hydroxypropyl trimethyl ammonium chloride
Cationic Guar Gum
Guar Hydroxypropyltrimnonium Chlide
gumguar2-hydroxy-3-(trimethylammonio)-propylet
jaguarc13s
GUM GUAR 2-HYDROXY-3-(TRIMETHYLAMMONIO)&
cosmediaguarc261
Guar,2-hydroxy-3-trimethylammoniopropylether,chloride
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
Synonyms: jaguarc14s;jaguarc15;jaguarc17;guar gum 2-hydroxy-3-(trimethylammonio) propyl ether chloride;Guar hydroxypropyltrimonium chloride;Gum guar 2-hydroxy-3-(trimethylammonio)propyl ether chloride;Guar Hydroxypropyltiamonium Chloride;Guar-hydroxypropyltrimethylammoniumchlorid (mittlere Molmasse ca. 2 000 000 g/mol) CAS: 65497-29-2
GUAR HYROXYPROPYL TRIMONIUM CHLORIDE
Guar hydroxypropyltrimonium chloride is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
Guar Hyroxypropyl Trimonium Chloride is a quaternary ammonium derivative of guar gum.
The chemical formula of Guar Hyroxypropyl Trimonium Chloride is C6H16NO2.


CAS Number: 65497-29-2
EC Number: 613-809-4
MDL Number: MFCD00217411
Molecular Formula: C10H14N5Na2O12P3
Origin(s): Vegetable , Synthetic
Classification: Quaternary ammonium , Propoxylated compound
Bio compatible


Further, Guar Hyroxypropyl Trimonium Chloride is used as a substitute for harsh silicones.
Guar Hyroxypropyl Trimonium Chloride is a yellow or white powdered ingredient that is obtained from guar beans.
Guar Hyroxypropyl Trimonium Chloride is a plant-based ingredient that is extracted from guar beans.
Even though it is sourced from natural means, Guar Hyroxypropyl Trimonium Chloride is still synthetic because of the way it is made.


After the extraction process is complete and a natural gum has been obtained from the guar beans, Guar Hyroxypropyl Trimonium Chloride is then purified and filtered.
Guar Hyroxypropyl Trimonium Chloride is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.


After this, the natural gum is reacted with epoxides to make Guar Hyroxypropyl Trimonium Chloride.
Guar Hyroxypropyl Trimonium Chloride is very safe and has almost no side effects.
Therefore, a patch test is recommended prior to use.
Other than this, there is no carcinogenicity or toxicity associated with Guar Hyroxypropyl Trimonium Chloride.


Moreover, Guar Hyroxypropyl Trimonium Chloride is biodegradable.
Guar Hyroxypropyl Trimonium Chloride is a conditioning agent for all kind of hair care preparations.
Guar Hyroxypropyl Trimonium Chloride is a synthetic quat (quaternary ammonium) derived from Guar gum.
Guar Hyroxypropyl Trimonium Chloride acts as a conditioning agent for skin and hair, it also has antistatic properties.


Guar Hyroxypropyl Trimonium Chloride is one of the synthetic molecules making an exception in the COSMOS specifications: it is therefore authorized in organic production. N
Guar Gum is obtained from the seed of a legume (Cyamopsis tetragonoloba).
Guar Hyroxypropyl Trimonium Chloride gives conditioning properties to shampoos and after-shampoo hair care products.


Guar Hyroxypropyl Trimonium Chloride is a water-soluble, organic compound.
Guar Hyroxypropyl Trimonium Chloride is plant derived from the guar (cluster bean) plant.
Although Guar Hyroxypropyl Trimonium Chloride is plant based, there is a synthetic portion to it.
Guar beans are harvested from the guar gum bush.


Guar Hyroxypropyl Trimonium Chloride is grown in India and Pakistan.
In the U.S., Guar Hyroxypropyl Trimonium Chloride is found in Texas.
Guar Hyroxypropyl Trimonium Chloride is generally considered safe.
This mostly depends on the amount used in the formula.


Guar Hyroxypropyl Trimonium Chloride should not exceed 1.0%.
Guar Hyroxypropyl Trimonium Chloride is a polysaccharide found in the seed of the guar plant, Cyamopsis tetragonoloba or C. psoraloid.
Crops have been grown in India and Pakistan for several thousands of years, and were introduced to the United States and other countries in the last century.


Guar Hyroxypropyl Trimonium Chloride is used as thickening agent in many food products and interacts with other thickening agents to provide an additive or synergistic effect.
Isolated from the endosperm of the plant seed, Guar Hyroxypropyl Trimonium Chloride has a molecular weight of approximately 200,000 kDa and contains a straight chain polysaccharide of D-mannose units connected by β (1→4) glycosidic linkages.


Alternating mannose units contain a single D-galactose unit attached by an α (1→6) glycosidic bond.
It is a derivatized form of Guar Hyroxypropyl Trimonium Chloride which includes a hydroxypropyl group on the pendant D-galactose unit.
Guar Hyroxypropyl Trimonium Chloride is a resinous material made from the guar bean.
Guar Hyroxypropyl Trimonium Chloride is a type of polysaccharide called galactomannan made from legume plants that consists of a polymannose backbone to which galactose groups are bound.


Derivatives of Guar Hyroxypropyl Trimonium Chloride that also may be used in cosmetics and personal care products include Hydroxypropyl Guar, Guar Hydroxpropyltrimonium Chloride and Hydroxypropyl Guar Hydroxypropyltrimonium Chloride.
Among these guar ingredients, Guar Hyroxypropyl Trimonium Chloride is most frequently used in cosmetic products.
Galactomannan polysaccharides, including Guar Hyroxypropyl Trimonium Chloride, are derived from plants of the bean (also called the Legume family).


These plants make galactomannan polysaccharides as a source of energy to support the growth of the embryo within the seed.
Guar Hyroxypropyl Trimonium Chloride is made of natural guar gum modified.
It's a kind of cationic polymer, Guar Hyroxypropyl Trimonium Chloride provides excellent thickening and conditioning properties for hair and skin care products.


A gift for humankind from nature itself, Guar Hyroxypropyl Trimonium Chloride comes in the form of a yellow or white powder, which is derived from guar beans synthetically and is utilized by hair care, pharmaceutical, and food processing industries.
Guar Hyroxypropyl Trimonium Chloride is a cationic guar gum polymer with superior water solubility and adsorption capacity, compatible with anionic, cationic, nonionic and amphoterics, low irritancy.


Guar Hyroxypropyl Trimonium Chloride can improve the rheology of the shampoo, conditioner and body wash.
The use of Guar Hyroxypropyl Trimonium Chloride in shower gel and hand wash brings excellent spreadability and feel after dry.
A shower gel or shampoo containing Guar Hyroxypropyl Trimonium Chloride has a thick texture and excellent spreadability for consumer convenience.


This water dispersible polysaccharide, Guar Hyroxypropyl Trimonium Chloride, is highly cationic over the entire useful pH range, is substantive to hair, and provides aesthetic benefits such as improved wet comb, detangling, conditioning, lustre, lubricity, and rich feel.
Guar Hyroxypropyl Trimonium Chloride can also contribute to increasing viscosity of formulations.
Guar Hyroxypropyl Trimonium Chloride is a water-soluble, organic compound that is a quaternary ammonium derivative of guar (aka cluster beans).


This means Guar Hyroxypropyl Trimonium Chloride is a substance whose chemical structure has four carbon groups attached to a positively charged nitrogen atom.
While plant derived, there is a synthetic portion to Guar Hyroxypropyl Trimonium Chloride.
While newer to the North American market, Guar Hyroxypropyl Trimonium Chloride has been found to be both mild and effective.


Further, studies have found Guar Hyroxypropyl Trimonium Chloride to be an excellent conditioning agent with even low concentrations proving effective at detangling hair and providing a smoother brushing experience.
Guar Hyroxypropyl Trimonium Chloride is derivative of natural guar gum; cationic guar is a quaternary, high cationic substitution, high molecular weight polymer that is substantive to anionic surfaces such as hair.


Guar Hyroxypropyl Trimonium Chloridesed in a wide range of personal care applications, it is a high molecular weight modified guar gum that is compatible with most anionic surfactants.
Allowing for a high deposition of actives, Guar Hyroxypropyl Trimonium Chloride provides texturizing, repairing, protecting, conditioning, moisturizing, and thickening properties.


Guar Hyroxypropyl Trimonium Chloride also provides color protection, soft hold, substantivity and improvement in ease of wet and dry combing.
The INCI name of this organic compound is Guar Hyroxypropyl Trimonium Chloride.
Guar Hyroxypropyl Trimonium Chloride in shampoo and conditioner provides the above-mentioned depositing and antistatic functions without weighing hair down.


Guar Hyroxypropyl Trimonium Chloride’s a white or yellow powder that is a quaternary ammonium derivative of guar gum.
Guar Hyroxypropyl Trimonium Chloride’s a plant derived and water-soluble derivative from guar beans, which come from the guar plant.
Guar plants are legumes and can be mainly found in Pakistan and India.
The guar beans are milled to obtain guar gum and this natural gum is purified and reacted to produce the guar hydroxypropyltrimonium chloride.


This product group is generally seen as safe to use and has a long history of reliable performance.
Guar Hyroxypropyl Trimonium Chloride doesn’t require CLP or GHS pictograms and for transport purposes it’s considered a non-dangerous good.
Guar Hyroxypropyl Trimonium Chloride is a cationic surfactant that has been shown to be effective in the treatment of vaginal atrophy.
Guar Hyroxypropyl Trimonium Chloride is a quaternized water-soluble derivative from natural Guar gum.


Guar Hyroxypropyl Trimonium Chloride is water-soluble so cannot be used with oil-only products.
Guar Hyroxypropyl Trimonium Chloride starts to hydrate very readily with water but can take up to 1 hour to become fully hydrated.
You may find that Guar Hyroxypropyl Trimonium Chloride starts to hydrate so quickly that it forms lumps.
These can be whisked out but could also mix the guar gum with a little glycerine or a vegetable oil first.


This slows down the hydration initially and helps to prevent lumps.
Once Guar Hyroxypropyl Trimonium Chloride is fully hydrated, the gel can be heated to 50°C but do ensure that it is quite fluid.
Very thick gels may be prone to scorching.
If the guar gum is added to cold water and then heated in a bain marie, it makes an exceptional gel that is very smooth and feels superb!


Guar Hyroxypropyl Trimonium Chloride is stable between pH 5 and 9.
If used at pH 3, you can feel some “pilling” as it starts to break down.
This can be modified by combining it with another thickening agent.
Unlike many commercial conditioners, Guar Hyroxypropyl Trimonium Chloride leaves no polymer build up.


The Guar Hydroxypropyltrimonium Chloride Market size is forecasted to grow at a CAGR of around 5.1% from 2022 to 2027.
Guar Hyroxypropyl Trimonium Chloride is an organic compound and water soluble that is a quaternary ammonium derivative of the guar.
The guar gum is a galactomannan polysaccharide present in the seed of guar plant or cyamopsis tetragonoloba.


Guar Hyroxypropyl Trimonium Chloride is a a pale yellow to beige coloured powder with a fishy odour that disappears once it has been blended with water.
Guar Hyroxypropyl Trimonium Chloride is a polysaccharide derivative of Guar Gum which is derived from guar beans, a legume which is commonly eaten as food in India.



USES and APPLICATIONS of GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
Guar Hyroxypropyl Trimonium Chloride gives conditioning properties to shampoos and after-shampoo hair care products.
The effects of the cationic charge density, guar concentration in aqueous solution, and treatment time on bleached European hair have been studied.
A mechanical testing method has been successfully applied to determine the efficacy of cationic guars to improve the ease of combing.


The results were confirmed in a shampoo formulation on both virgin and bleached hair.
Guar Hyroxypropyl Trimonium Chloride is generally used in shampoos and other hair products where it acts as a conditioner and an anti-static agent.
Guar Hyroxypropyl Trimonium Chloride is also used in skin care products where it deeply conditions the skin.


Guar Hyroxypropyl Trimonium Chloride is used in hair conditioning products.
Gums are used to impart creaminess.
They are thus added to dairy products.
They also are used in place of ingredients that contain gluten.


The best known food in which this has occurred is certain breads.
Guar Hyroxypropyl Trimonium Chloride is a great conditioning agent for both skin and hair.
Guar Hyroxypropyl Trimonium Chloride is especially beneficial as a hair care product.
Because it is positively charged, or cationic, Guar Hyroxypropyl Trimonium Chloride neutralizes the negative charges on hair strands that cause hair to become static or tangled.


Better yet, Guar Hyroxypropyl Trimonium Chloride does this without weighing hair down.
With Guar Hyroxypropyl Trimonium Chloride, you can have silky, non-static hair that retains its volume and provides a smoother brushing experience.
Guar Hyroxypropyl Trimonium Chloride is commonly used as a conditioning agent in shampoo formulations.


Guar Hyroxypropyl Trimonium Chloride forms a coacervate with anionic surfactants from the shampoo formulation upon dilution and deposits on the surface of hair providing conditioning in the form of reduced wet combing forces.
The dilution and deposition phenomenon occurs when the system is diluted below the critical micelle concentration of the shampoo surfactants, resulting in the formation of the insoluble coacervate.


The properties of the formed coacervate depend on a variety of characteristics of the polymer, including molecular weight and charge density, as well as the composition of surfactants and presence of electrolytes.
In addition, Guar Hyroxypropyl Trimonium Chloride has reported uses in liquid soap and body wash formulations, hair conditioners, hair styling products, and skin care preparations.


Guar Hyroxypropyl Trimonium Chloride may be used in bath products, hair conditioners, hair dyes, other hair care products and skin care products.
Guar Hyroxypropyl Trimonium Chloride and the other guar derivatives may also be used in bath products, hair care products, shaving preparations and skin care products.


In addition to being used in cosmetics and personal care products, Guar Hyroxypropyl Trimonium Chloride is commonly used as a thickener in foods such as salad dressings, ice cream and soups.
Hydroxypropyl Guar is also used in artificial tear solutions.
In personal care industry Guar Hyroxypropyl Trimonium Chloride's usually used as conditioner, thickeners and stabilizers, also it's widely used in shampoo, shower gel, liquid soap, cream and other products since it has good compatibility in the formula.


Guar Hyroxypropyl Trimonium Chloride is mainly used to give conditioning benefits to surfactant based formulations such as shampoos, body washes and shaving preparations.
Guar Hyroxypropyl Trimonium Chloride is substantive to the hair where it has been proven to reduce tangling, improve hair feel, styling ability and gloss.


As this turns solutions cloudy Guar Hyroxypropyl Trimonium Chloride is best suited for pearlescent or coloured formulations or emulsions.
Among these guar ingredients, Guar Hyroxypropyl Trimonium Chloride is most frequently used in cosmetic products.
Guar Hyroxypropyl Trimonium Chloride may be used in bath products, hair conditioners, hair dyes, other hair care products and skin care products.


Guar Gum and the other guar derivatives may also be used in bath products, hair care products, shaving preparations and skin care products.
Guar Hyroxypropyl Trimonium Chloride has excellent conditioning due to its cationic nature, imparts essential smoothness, and can be used in a wide variety of hair care applications including shampoos, conditioners, and hair creams.


Guar Hyroxypropyl Trimonium Chloride can also be formulated into skin care applications like facial washes, cleansers, creams, and lotions and 2 in 1 shampoo.
Guar Hyroxypropyl Trimonium Chloride is recommended for use in conditioners, hair masks, shampoos, detangling products, and nourishing and healing skin care products.


Guar Hyroxypropyl Trimonium Chloride is a so-called cationic substance (with positive charge) obtained from guar gum.
Guar Hyroxypropyl Trimonium Chloride prevents the static charging of the hair, improves the combability of the hair and increases the creaminess in surfactant formulations such as shampoo, shower gel etc.
Guar Hyroxypropyl Trimonium Chloride also has a smoothing effect on hair and skin.


Guar Hyroxypropyl Trimonium Chloride has been shown to be an excellent antimicrobial agent for the prevention and treatment of microbial infection.
Guar Hyroxypropyl Trimonium Chloride has also been used as a detergent additive.
The hydroxyl group on Guar Hyroxypropyl Trimonium Chloride interacts with fatty acids, causing it to form a complex with citric acid, which increases its effectiveness in reducing bacterial populations.


The citric acid-Guar Hyroxypropyl Trimonium Chloride complex also inhibits the growth of gram-positive bacteria such as Staphylococcus and Streptococcus species.
Guar Hydroxypropyltrimonium Chloride forms a "free breathing" film on hair and skin, and generates good protection, moisturization, conditioning, lightweight feel, shiny, soft, healthy looking hair.


Guar Hyroxypropyl Trimonium Chloride's a unique naturally-derived solution for oil-based and silicone-free shampoos offering conditioning performance even in sulfate-free formulations.
Guar Hyroxypropyl Trimonium Chloride improves conditioning of hair in both the wet and dry state.
This is due to the fact that Guar Hyroxypropyl Trimonium Chloride's cationic charge makes the product substantive to anionic surfaces such as hair and skin.


Guar Hyroxypropyl Trimonium Chloride can form a “free breathing” film on hair and skin, and generate good protection, moisturization, condition and lubricity.
Guar Hyroxypropyl Trimonium Chloride is easily dispersed in water due to extra surface treatment.
Guar Hyroxypropyl Trimonium Chloride brings visual conditioning efficacy to Shampoo, Shower Gel, Hair Conditioner and Skin Care products.


Guar Hyroxypropyl Trimonium Chloride has high formula tolerance that can be well used in faintly acid systems.
Guar Hyroxypropyl Trimonium Chloride increases deposition of silicon oil on hair significantly.
Guar Hyroxypropyl Trimonium Chloride has good cooperativity with silicon oil in formula.
Guar Hyroxypropyl Trimonium Chloride is with excellent conditioning efficacy, and good absorption.


To repair damaged hair and thicken the formula.
Guar Hyroxypropyl Trimonium Chloride reduced the irritation from anionic surfactants, and improve hair wet / dry combing.
Guar Hyroxypropyl Trimonium Chloride is a conditioning ingredient that is used in both skincare and hair care products.
Guar Hyroxypropyl Trimonium Chloride is a water-soluble ingredient that is derived from plant-based sources.


Guar Hyroxypropyl Trimonium Chloride is generally used in hair care products as it helps to reduce static while retaining volume.
Guar Hyroxypropyl Trimonium Chloride is most widely used in hair care products due to the added benefit of helping to reduce static between hair strands.
This helps to reduce frizz and minimize flyaways.


Guar Hyroxypropyl Trimonium Chloride does this through its positive charge, neutralizing the negative charges on the hair that cause static.
Guar Hyroxypropyl Trimonium Chloride is also a lightweight ingredient as is often used in place of other anti-static ingredients that are heavier, weighing the hair down.
Guar Hyroxypropyl Trimonium Chloride provides good substantivity together with no build-up on hair.


Guar Hyroxypropyl Trimonium Chloride allows the development of transparent foaming formulations, thanks to its good compatibility with anionic and amphoteric surfactants commonly used in personal care products.
Guar Hyroxypropyl Trimonium Chloride provides excellent wet-combing and wet-feel properties.
Guar Hyroxypropyl Trimonium Chloride enhances as well the deposition of actives such as silicones, oils, anti-dandruff agents on hair.


Guar Hyroxypropyl Trimonium Chloride is ideal for transparent or opaque conditioning shampoos and cream rinses for colored or damaged hair.
Guar Hyroxypropyl Trimonium Chloride can be used in shampoos, hair conditioners and hair packs where it not only provides thickness and texture to the product but also improves hair combing and brushing without tangling and reduces breakage.
Its film forming ability also makes Guar Hyroxypropyl Trimonium Chloride substantive to the hair, giving it some greater volume.


Though it may have a long name, Guar Hyroxypropyl Trimonium Chloride is simply a conditioning extract made from Guar Gum that offers a natural solution for tangled hair.
Guar Hyroxypropyl Trimonium Chloride has major application in the cosmetics and personal care sector in hair care, skin care, soap, shower gels, and others.


Guar Hyroxypropyl Trimonium Chloride is a conditioning agent and offers major demand in the hair care applications, thereby creating a drive in the guar hydroxypropyltrimonium chloride market.
Furthermore, the increasing production and growth in the personal care products, cosmetics preparation, and surfactant sector will provide major growth in the market during the forecast period.
Guar Hyroxypropyl Trimonium Chloride is used in formulations at 0.5% to 2% or higher if needed.


-Skin Care uses of Guar Hyroxypropyl Trimonium Chloride:
Guar Hyroxypropyl Trimonium Chloride attaches to the skin to form a conditioning and protective polymeric film, giving a very elegant skin feel to the finished product.
Guar Hyroxypropyl Trimonium Chloride can be used to stabilise creams and lotions that have a lot of actives that may be challenging to the emulsion.
Guar Hyroxypropyl Trimonium Chloride will also add some thickness to the finished product.
Guar Hyroxypropyl Trimonium Chloride can hold a small amount of oil in suspension without settling, which is an ideal way to get Omega 3 rich oils into a product without heating them.


-Hair Care uses of Guar Hyroxypropyl Trimonium Chloride:
As it is cationic, Guar Hyroxypropyl Trimonium Chloride attaches itself to the anionic hair shaft to form a conditioning and protective polymeric film, protecting the hair whilst keeping it hydrated and flexible.


-Applications of Guar Hyroxypropyl Trimonium Chloride:
*Hair Care:
Shampoo, conditioner, mask, treatments, hair colorants
*Body Cleansing:
Shower products, facial cleansers, feminine hygiene
*Skin Care:
Face and neck care, body care, eye care, sun care, hand/nail/foot care
*Health & Hygiene:
Deodorants, personal insect repellents


-Cosmetic Uses of Guar Hyroxypropyl Trimonium Chloride:
*antistatic agents
*film formers
*skin conditioning
*viscosity controlling agents


-Applications of Guar Hyroxypropyl Trimonium Chloride:
*Hair care
*Shampoo
*Shower gel


-Key applications of Guar Hyroxypropyl Trimonium Chloride:
*Hair care
*Shampoo
*Personal care
*Cosmetic products
*Soaps and detergents
*Beauty products
*Industries
*Cosmetics


-Antistatic agents:
*Guar Hydroxypropyltrimonium Chloride, Hydroxypropyl Guar Hydroxypropyltrimonium Chloride Binders
*Cyamopsis Tetragonoloba (Guar) Gum, Hydroxypropyl Guar Emulsion stabilizers
*Cyamopsis Tetragonoloba (Guar) Gum, Hydroxypropyl Guar


-Film formers:
*Hydroxypropyl Guar Hair conditioning agents
*Guar Hydroxypropyltrimonium Chloride, Hydroxypropyl Guar Hydroxypropyltrimonium Chloride Skin-conditioning agents


-miscellaneous:
Guar Hydroxypropyltrimonium Chloride Viscosit increasing agents
-aqueous:
Cyamopsis Tetragonoloba (Guar) Gum, Hydroxypropyl Guar, Guar Hydroxypropyltrimonium Chloride


-HAIR CARE uses of Guar Hyroxypropyl Trimonium Chloride:
*Exceptional conditioning properties at lower usage levels (0.1%- 0.3% in formulation).
Smooth hair and soft skin feel.
Easier to manage hair

*Guar Hyroxypropyl Trimonium Chloride increase adhesion and substantivity of polymer to hair.
Excellent wet & dry hair combing and detangling.
Guar Hyroxypropyl Trimonium Chloride enhances foam sensorial attributes.
Soft hold and improved shine

*Excellent antistatic in hair care & skin care.
High dispersion capacity in hot & cold water.
Controlled deposition with no build-up
*Guar Hyroxypropyl Trimonium Chloride is enhanced silicone uptake on hair and enhanced anti-dandruff deposition


-SKIN CARE uses of Guar Hyroxypropyl Trimonium Chloride:
*Excellent antistatic in hair care & skin care Restoration of skin's pH buffering capacity fivetimes faster
*Reduction of skin stiffening effects of surfactants.
High dispensive capacity in hot & cold water Reduced skin irritation and redness with 40%improved effectiveness


-ORAL CARE uses of Guar Hyroxypropyl Trimonium Chloride:
*Excellent hydration better stabilizes the solution.
Salt-tolerant, resistant to 10% CaCl2 or 5% NaCl solution.
Special lubricity, improve the mouthfeel of paste,reduce the tooth wear.
*Improve the paste to be more smooth & bright.
Enhance the stability of paste.
Rich foam, soft & smooth



BENEFITS OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE
This cationic polymer, Guar Hyroxypropyl Trimonium Chloride, is substantive to the hair where it improves wet and dry combability.
Guar Hyroxypropyl Trimonium Chloride is compatible with anionic, nonionic and cationic surfactants and is suitable for cold processing.



HOW TO USE OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
Disperse some powder in water at room temperature.
Stir with moderate agitation.
Add citric acid or phosphoric acid or hydrochloric acid to neutralize the solution.
Add the remaining ingredients to the formulation.



BENEFITS OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
*Substantivity to hair and skin
*Surfactant compatibility
*Viscosity modification
*Lubricity
*Imparts smooth, rich feel to hair and skin
*Improves wet and dry combability
*Improves gloss and anti-static properties on hair
*Excellent heat and pH resistance
*Hair hydrophobicity improvements
*Yields nice viscous qualities
*Great conditioning agent
*Easier wet & dry combing
*Smoother brushing experience
*Natural guar gum origin



FUNCTIONS OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
*Antistatic:
Guar Hyroxypropyl Trimonium Chloride reduces static electricity by neutralizing the electrical charge on a surface
*Film forming agent:
Guar Hyroxypropyl Trimonium Chloride produces a continuous film on the skin, hair or nails
*Skin conditioning agent:
Guar Hyroxypropyl Trimonium Chloride keeps the skin in good condition
*Viscosity control agent:
Guar Hyroxypropyl Trimonium Chloride increases or decreases the viscosity of cosmetics
*Guar Hyroxypropyl Trimonium Chloride is a water-soluble derivative of natural guar gum, and delivers conditioning properties to shampoos and after-shampoo hair care products.



IN PERSONAL CARE OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
In personal care products Guar Hyroxypropyl Trimonium Chloride’s widely known for its anti-static, conditioning, and viscosity properties, especially in shampoo formulation.
Guar hydropropyltrimonium chloride hair functions are:

1) reduction of static created between hair strands, which ensures non static hair by neutralizing the negative charges on the hair because it’s positively charged
2) in shampoo and other hair care products it’s a great conditioning agent.
While primarily used in hair care products, guar hydroxypropyltrimonium chloride in skin care and body care products is formulated mainly as skin conditioning agent.

Guar Hyroxypropyl Trimonium Chloride is a naturally derived cationic polymer that provides excellent conditioning and thickening for hair and skin care products.
Guar Hyroxypropyl Trimonium Chloride imparts a soft, elegant after-feel to the skin and also enhances wet comb and dry comb properties to shampoo and hair conditioning systems.



WHAT IS GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE USED FOR?
The main function of Guar Hyroxypropyl Trimonium Chloride is to extend conditioning properties to hair care products.
Guar Hyroxypropyl Trimonium Chloride is also sometimes used in skin care products to achieve the same results.

-Hair care:
Guar Hyroxypropyl Trimonium Chloride is a positively charged ingredient, that cancels the negative charge on hair causing it to have a static or become tangled.
Guar Hyroxypropyl Trimonium Chloride makes the hair silky smooth without weighing them down

-Skin care:
Guar Hyroxypropyl Trimonium Chloride nourishes the skin and also increases the viscosity of the formulations



BENEFITS AND USES OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
*This immensely nourishing ingredient, Guar Hyroxypropyl Trimonium Chloride, makes your hair look like silk.
*Guar Hyroxypropyl Trimonium Chloride will strengthen your hair and add unimaginable volume and luster to it.
*Guar Hyroxypropyl Trimonium Chloride extirpates dryness colossally and prevents split ends.
*Guar Hyroxypropyl Trimonium Chloride binds to the keratin in your hair and the skin and makes it seemingly moisturized.
*You can also use Guar Hyroxypropyl Trimonium Chloride in formulating artificial tear solutions and as a thickener in salad dressings.
*Guar Hyroxypropyl Trimonium Chloride is completely safe and above all, it is non-carcinogenic.



FEATURES AND BENEFITS OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
*Purified guar derivative providing hair conditioning benefits
*Suitable for baby shampoo formulations
*Suitable for clear, silicone-free solution

*Hair Care:
Increased deposition and substantivity to hair
Controlled delivery of water-insoluble substances
Exceptional conditioning properties at lower usage levels
Excellent wet/dry hair combing and detangling

*Body Care:
Reduced skin stiffening caused by surfactants
Restored skin’s pH buffering effects are 5 times faster
Increased deposition and substantivity to skin
Enhancement of foam sensorial attributes



HOW GUAR HYROXYPROPYL TRIMONIUM CHLORIDE WORKS:
Guar Hyroxypropyl Trimonium Chloride acts as an emulsifier and thickener that improves the consistency of the product.
Guar Hyroxypropyl Trimonium Chloride works as an anti-static agent by forming a thin film on the surface of the hair and skin.
Guar Hyroxypropyl Trimonium Chloride is generally used at a concentration of 0.2%-1.0%.
Guar Hyroxypropyl Trimonium Chloride is readily soluble in water but is insoluble in oils.



PROPERTIES OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
Guar Hyroxypropyl Trimonium Chloride is a biopolymer. Therefore, many of its properties will depend on Guar Hyroxypropyl Trimonium Chloride's molecular weight and charge density, which is subject to the degree of cationic substition.
Guar Hyroxypropyl Trimonium Chloride is soluble in water. Guar Hyroxypropyl Trimonium Chloride is insoluble in alcohol and oils.
Guar Hyroxypropyl Trimonium Chloride's melting point is 170 ˚C.



WHAT ARE THE BENEFITS OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE IN HAIR CARE AND BEAUTY?
Guar Hyroxypropyl Trimonium Chloride thickens our formulas and conditions your hair, nixing static without weighing you down.
* A conditioning chemical added to hair products for easy detangling
Guar Hyroxypropyl Trimonium Chloride is a water-soluble derivative of natural guar gum, and delivers conditioning properties to shampoos and after-shampoo hair care products.
* A conditioning chemical added to hair products for easy detangling



WHY IS GUAR HYROXYPROPYL TRIMONIUM CHLORIDE USED?
Although a great conditioning agent for both skin and hair, Guar Hyroxypropyl Trimonium Chloride is especially beneficial as a hair care product.
Because Guar Hyroxypropyl Trimonium Chloride is positively charged, or cationic, it neutralizes the negative charges on hair strands that cause hair to become static or tangled.
Better yet, Guar Hyroxypropyl Trimonium Chloride does this without weighing hair down.
With this ingredient, you can have silky, non-static hair that retains its volume.



WHAT YOU NEED TO KNOW ABOUT GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
When Guar Hyroxypropyl Trimonium Chloride comes to natural products, many consumers aren’t fazed by ingredients such as aloe Vera, Rosemary or Witch Hazel, but there are other, more obscure ingredients that may be long-named, difficult to pronounce or simply seem intimidating.
However, they are actually quite natural, beneficial and most importantly, safe.
Guar Hyroxypropyl Trimonium Chloride is one of these.
And Guar Hyroxypropyl Trimonium Chloride isn’t nearly as scary as an ingredient as it is to pronounce or spell.



GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
THE GOOD:
Guar Hyroxypropyl Trimonium Chloride helps to condition the skin and reduce static created between hair strands, reducing frizz and flyaways.
THE NOT SO GOOD:
Nothing to report here, Guar Hyroxypropyl Trimonium Chloride is actually a widely used ingredient in the skincare industry and is particularly useful for hair care products.



WHO IS GUAR HYROXYPROPYL TRIMONIUM CHLORIDE FOR?
All skin types except those that have an identified allergy to Guar Hyroxypropyl Trimonium Chloride.
Guar Hyroxypropyl Trimonium Chloride works well with most ingredients.
Guar Hyroxypropyl Trimonium Chloride is a conditioning agent for both the skin and hair which means that it helps to moisturize.
While Guar Hyroxypropyl Trimonium Chloride is sometimes used in skincare formulations it is more often used in hair care products.



IS GUAR HYROXYPROPYL TRIMONIUM CHLORIDE SAFE?
The Cosmetic Ingredient Review Expert Panel, a group responsible for evaluating the safety and efficacy of skincare and cosmetic ingredients has reviewed the available data on Guar Hyroxypropyl Trimonium Chloride.
Guar Hyroxypropyl Trimonium Chloride is based on the available research the Expert Panel determined that guar hydroxypropyltrimonium chloride is safe for use.
There was no toxicity or carcinogenicity issues present with this ingredient or related ingredients.



IMPORTANT CRITERIA OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
*palm oil-free
*vegan
*animal non testing
*Non GMO



WHAT ARE THE BENEFITS OF GUAR HYROXYPROPYL TRIMONIUM CHLORIDE?
*Antistatic
*Detangles hair
*conditioning



WHAT DOES GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE DO IN A FORMULATION?
*Antistatic
*Hair conditioning
*Skin conditioning
*Viscosity controlling



PHYSICAL and CHEMICAL PROPERTIES of GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
Density: 1.3
Melting Point: >300°C
Solubility: Soluble in water
Viscosity: High
Appearance: Light yellow powder
Color: Light yellow powder
Viscosity (1% water solution): 3000-4000
Size: 160 MESH
Moisture: ≤10 %
pH value (1% water solution): 7-8
nitrogen content: 1.5-2.0%
Saccharomycetes: ≤100 cfu/g
total bacteria count: ≤500 cfu/g
Staphylococcus aureus: Not find
Escherichia coli: Not find
Pseudomonas aeruginosa: Not find
salmonella: Not find
As: ≤1.0 mg/kg
Pb: ≤1.0 mg/kg
Molecular Formula: C6H16NO2.xCl.xUnspecified
Density: 1.3 g/mL at 25 °C(lit.)
Melting Point: >300 °C(lit.)
Appearance: Yellow powder
Storage Condition: Room Temprature

Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Appearance: Powder
Colour: Yellowish
Odour: Negligible
pH: 9.0-11.0
Melting point: No data available.
Boiling point: No data available.
Density: No data available.
Vapour pressure: No data available.
Partition coefficient (n -octanol/water): No data available.
Solubility(ies): Soluble in water.
Flash point: >93℃.
Auto-ignition temperature: 199 ℃
Flammability: No data available.
Explosive properties: No data available.
Oxidising properties: Not applicable.
Evaporation rate: No data available.
Viscosity: No data available.
Other information: Loss on Drying (105 ⁰C: ≤12.0%)



FIRST AID MEASURES of GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
-Description of first aid measures:
*Following inhalation:
Remove from exposure and move to fresh air immediately.
*Following skin contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
*Following eye contact:
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.
*Following ingestion:
Rinse mouth.
Get medical aid immediately.
Notes for the doctor:
Treat symptomatically and supportively.
-Most important symptoms and effects, both acute and delayed:
No information available.
-Indication of any immediate medical attention and special treatment needed:
No information available.



ACCIDENTAL RELEASE MEASURES of GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
-Environmental precautions:
Do not flush into surface water or sanitary sewer system.
-Methods and material for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
-Extinguishing media:
*Suitable extinguishing media:
Powder, alcohol-resistant foam, water spray, carbon dioxide.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Advice for firefighters:
Prevent fire-fighting water from entering surface water or groundwater.



EXPOSURE CONTROLS/PERSONAL PROTECTION of GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
-Exposure controls
--Personal protective equipment:
*Eye and face protection:
Wear safety glasses with side shields.
*Skin protection:
Protective suit.
*Hand protection:
Use protective gloves.
-Environmental exposure controls:
Do not let product enter drains.
*Industrial hygiene:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday



HANDLING and STORAGE of GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
-Precautions for safe handling:
No smoking.
Dispose of rinse water in accordance with local and national regulations.
-Conditions for safe storage, including any incompatibilities:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of GUAR HYROXYPROPYL TRIMONIUM CHLORIDE:
-Reactivity:
Stable under recommended storage and handling conditions.
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No information available.



SYNONYMS:
Guar, 2-hydroxy-3-trimethylammoniopropyl ether, chloride
2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER CHLORIDE GUAR GUM
CHLORIDE GUAR GUM
2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER
GUAR GUM, 2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER
CHLORIDE, GUAR GUM, 2HYDROXY3(TRIMETHYLAMMONIO)PROPYL ETHER
CHLORIDE GUAR GUM
ETHER WITH 3-CHLORO-2-HYDROXYPROPYLTRIMETHYLAMMONIUM CHLORIDE
GUAR 2-HYDROXY-3-TRIMETHYLAMMONIOPROPYL ETHER CHLORIDE
GUAR HYDROPROPYLTRIMONIUM CHLORIDE
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
O-[2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL] GUAR GUM CHLORIDE
Cyamopsis tetragonoloba (guar) gum, guar gum, guaran†
Molecular formula: variable
Molecular weight: variable
Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride
Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride
B16G315W7A
65497-29-2
UNII-B16G315W7A
Jaguar C 14S
Jaguar C 15
Jaguar C 17
Guar hydroxypropyltrimonium chloride
Cosmedia Guar C 261
Guar gum, ether with 3-chloro-2-hydroxypropyltrimethylammonium chloride
Guar, 2-hydroxy-3-trimethylammoniopropyl ether, chloride
Jaguar C 13S
GUM GUAR 2-HYDROXY-3-(TRIMETHYLAMMONIO)
cosmediaguarc261
Guar,2-hydroxy-3-trimethylammoniopropylether,chloride
Guargum,etherwith3-chloro-2-hydroxypropyltrimethylammoniumchloride
gumguar2-hydroxy-3-(trimethylammonio)-propylet
jaguarc13s
jaguarc14s
jaguar
Guarhydroxypropyl-Trimoniumchlorid,Hydroxylpropyl Guar,Hydroxypropyltrimonium Chloride
Guarhydroxypropyltrimoniumchlorid
Cosmedia Guar C261N
Guar Hydroxypropyl Trimonium Chloride
Trimethylammoniopropyl Guar Chloride 100%
Uniguar C261
jaguarc13s
Cationic Guar Gum
Guar Hydroxypropyltrimnonium Chlide
Guar hydroxypropyltrimonium chloride
gumguar2-hydroxy-3-(trimethylammonio)-propylet
Guar hydroxypropyl trimethyl ammonium chloride

GUERBET C20
Guerbet C20 is a naturally-derived, odorless, colorless, medium spreading emollient typically used in lip care products.
Guerbet C20 adds moisture with no greasy feel and is excellent for pigment dispersion and solubilization of small particle solids and actives.


CAS Number: 5333-42-6
EC Number: 226-242-9
MDL Number: MFCD01310428
Chemical formula: C20H42O


Guerbet C20 is a branched-chain primary alcohol used as the isomer 2-octyl-1-dodecanol in cosmetics such as lipstick, or as an anti-blooming agent in facepowder.
Guerbet C20 is a medium spreading emollient, with equilibrium spreading pressure of 17.0 dyne/cm.
Guerbet C20 is in the class of Guerbet alcohols, because it has the branch at the β position.


Compared to arachidyl alcohol, the linear alcohol of the same molecular weight, Guerbet C20 has a lower melting point, yet retains low volatility.
Guerbet C20 is a primary, saturated alcohol with defined branching of the carbon chain.
Such alcohols are chemically described as Guerbet C20s and are also referred to as Guerbet alcohols.


Guerbet C20 is a high purity alcohol that offers excellent oxidative and color stability.
Additionally, the twin, 100% linear alkyl branches of the Guerbet C20 alcohol give it a lower viscosity and better biodegradability than dimer alcohols derived from oxo-alcohols.
Guerbet C20 is medium spreading qualities.


The unique chemical structure of Guerbet C20 alcohol also provides good solubility and solvency.
Guerbet C20's chemical formula is C20H42O.
Guerbet C20 is an odorless and clear fatty acid that is used to improve the texture of cosmetic products.
Guerbet C20 has amazing solvent properties that bring stability to cosmetic formulations and also gives a really smooth feel to the final product.


Guerbet C20 is a long chain fatty alcohol.
Guerbet C20 is a clear, odorless fatty alcohol with excellent solvent properties.
Guerbet C20 is produced from natural fats (non animal) and oils by reduction of the fatty acid grouping to the hydroxyl function.
Guerbet C20 has medium spreading qualities.


Guerbet C20 is a medium spreading emollient which is due to its chemical structure hydrolysis stable and therefore beneficially suitable for all formulations where a wide pH range is needed e.g. deodorant/antiperspirant and hair remover formulations.
Guerbet C20 is a clear, slightly yellow, odorless oil of low polarity with a mean molecular weight, and a spreading value of 600 mm^2/10 min.
Guerbet C20 has a hydroxyl value of 184-190, a refractive index (20°C) of 1.4535-1.4555, and a density (20°C) of 0.837-0.841 g/cm^3.


Guerbet C20 has wonderful solvent properties that can be used in most cosmetic formulations, aiding stability and adding a softening feel to your final formulation.
Guerbet C20 is a clear and odourless fatty acid that is derived from vegetable fats and oils by reduction of the fatty acid grouping to the hydroxyl function.
Guerbet C20 is a clear, slightly yellow, odorless oil that's a very common, medium-spreading emollient.
Guerbet C20 makes the skin feel nice and smooth and works in a wide range of formulas.


Guerbet C20 is authorized in organic.
Guerbet C20 is produced from natural fats and oils.
Guerbet C20 is a mineral wax used as a texture enhancer in cosmetics, especially to add stability to lipsticks and stick foundations and keep them blended.
Guerbet C20 is a long chain and branched fatty alcohol.


Guerbet C20 is clear and colorless to yellow liquid, which is also odorless and insoluble in water.
Guerbet C20 is obtained from vegetable oils derived from fats.
Chemically, Guerbet C20 is produced by the reduction of fatty acids.
Guerbet C20 (Synonym: 2-octyl dodecanol) is a clear, odorless fatty alcohol with excellent solvent properties.


Guerbet C20 is produced from natural fats (non animal) and oils by reduction of the fatty acid grouping to the hydroxyl function.
Guerbet C20 is a slightly yellow, clear, odorless fatty alcohol with low polarity, higher stability, and excellent wetting and solubilizing properties.
Guerbet C20 is useful in a wide range of pH values and is stable against hydrolysis, which makes it a base ingredient (up to 20%) of a choice for many formulations including sun care products.


Guerbet C20 can serve as a carrier for fragrance, solubilize many sparingly soluble ingredients like salicylic acid, and disperse pigments and small particle solids in color cosmetics.
Guerbet C20 improves the sensory profile of a product and lessens the greasy feel sensation in oily formulas.
Guerbet C20 is non-volatile and is very different from alcohols like isopropyl (rubbing) alcohol and ethanol.


Guerbet C20 is more like carrier oils than ethanol.
Guerbet C20 is also known as 2-Octyl-1-dodecanol.
Guerbet C20 is very useful if you are formulating with salicylic acid.



USES and APPLICATIONS of GUERBET C20:
Guerbet C20 is a branched-chain primary alcohol used as the isomer 2-octyl-1-dodecanol in cosmetics such as lipstick, or as an anti-blooming agent in facepowder.
Guerbet C20 is used as an intermediate in medicine, organic and materials.
Guerbet C20 have been used as a emulsion stabilizer for polymer matrix patches.


Guerbet C20 (Cat No.:R017639) also known as Exxal 20; Guerbet C20; Isofol 20; Jarcol I 20; NSC 2405, 2-Octyl-1-dodec-2-octyldodecanol is used as an intermediate in pharmaceuticals, organics, and materials.
Apart from cosmetics, Guerbet C20 is also used in skin care products due to its emollient and lubricating abilities.


Any cosmetic product can have Guerbet C20 - from cleansers and lotions to lipsticks and eye makeup.
Guerbet C20 is a great solvent and a binder as it keeps the ingredients from separating in a product as well as improves their texture.
Guerbet C20 works well with almost all the ingredients and aids stability.
Guerbet C20 is a safe ingredient and can be used in a range of cosmetic and skin care products without a problem.


Guerbet C20 is even non-comedogenic which means that it will not block the pores.
However, a patch test is recommended prior to application.
Further, being derived from natural sources makes Guerbet C20 halal.
Guerbet C20 moisturises skin & hair, stabilises lotions & creams and is an excellent solvent for perfumes.


Guerbet C20 is the cosmetic ingredient to try if you are having stability problems with your formulation.
Guerbet C20 can be used in almost any cosmetic product, from lip balm to skin lotions, facial cleansers and color cosmetics, silicone alternative.
Guerbet C20 is stable to hydrolysis and can be used over a wide pH range.
Guerbet C20 can be used in almost all cosmetic formulations from lips balms to skin lotions to shower gels to cleansers.


Guerbet C20 acts as a good silicone alternative giving excellent emollient properties for a soft and smooth skin surface.
Guerbet C20 is a fatty alcohol used for its solvent and emollient properties in cosmetics.
Guerbet C20 can be easily used in a wide range of cosmetics, it moisturizes the skin and hair, stabilizes lotions and creams.
Guerbet C20 is used as a solvent in perfumes.


Guerbet C20 is a stable compound and can be used over a wide range of pH values.
Guerbet C20 can be used in almost any cosmetic product, from lip balm to skin lotions, facial cleansers and color cosmetics, silicone alternative.
Guerbet C20 is stable to hydrolysis and can be used over a wide pH range.
Guerbet C20 is used solvent for perfume ingredients, also salicylic acid.


Add Guerbet C20 to formulas as is, add to the oil phase, typical use level 2-20%.
Guerbet C20 is used for external use only.
Guerbet C20 is used all kinds of skin care, sun care products, various color cosmetics.
Thanks to its medium spreading ability, Guerbet C20 can be useful in almost all types of skin, lip, and hair care applications and decorative cosmetics in various consistency from liquid lotions to solid balms.


This pharmaceutical-grade ingredient, Guerbet C20, can serve as a solvent or emollient with a good moisturizing property.
Guerbet C20 is a skincare and cosmetic ingredient that is used to improve the texture of products.
Guerbet C20 is often used in moisturizers and lip products due to its emollient and lubricating abilities.
Guerbet C20 is a clear colorless liquid and is often used in products such as cleansers, eye makeup, foundations, conditioners, moisturizers, and lip balms.


Guerbet C20 is primarily used to improve the texture of formulations.
Guerbet C20 helps to form emulsions and prevents the separation of the oil and water-based ingredients.
Guerbet C20 also acts as a lubricant, improving the appearance of the skin, giving it that soft smooth look.
The other little benefit of Guerbet C20 is that it prevents the ingredients in a formulation from foaming when shaken.


This improves the stability of Guerbet C20 during transport and use.
Guerbet C20 is a medium-spreading emollient which is due to its chemical structure hydrolysis stable and therefore beneficially suitable for all formulations where a wide pH range is needed e.g. deo/antiperspirant and hair remover formulations.
Guerbet C20 is an emulsifier and opacifying agent, used primarily as a thickener in moisturizers because of its lubricating and emollient properties in the formulation of skin care products.


Guerbet C20’s very versatile and can be used like liquid carrier oils in many applications.
Guerbet C20 is popular in colour cosmetics as it improves pigment dispersion (some manufacturers sell pigments pre-dispersed in a base of octyldodecanol).
If Guerbet C20 is being used as a salicylic acid solvent I’m afraid I don’t have many suggestions; Guerbet C20 is an excellent salicylic acid solvent with a much higher ability to dissolve salicylic acid than most other options.


Guerbet C20 is used for solvent for perfume ingredients, also salicylic acid.
Guerbet C20 is used emollient, solvent, and moisturizer for all kinds of skin care products.
Guerbet C20 provides the skin a soft, smooth appearance. Ideal solvent to dissolve salicylic acid.


-Skin care:
Guerbet C20 provides a smooth texture to skin care products. Even though it is an alcohol, Guerbet C20 helps the skin retain moisture without drying it out.
Guerbet C20 provides hydrating properties to lotions and sunscreens while biding the ingredients together.
Guerbet C20 is non-comedogenic and is too big to penetrate the skin, making it a great barrier against all types of harmful particles


-Perfumery:
Guerbet C20 helps improve the scent
-Applications of Guerbet C20 include but are not limited to:
*Color cosmetics
*lip balms and lipsticks
*Lotions and creams



FUNCTIONS OF GUERBET C20:
*Emollient
*Moisturizer
*Carrier
*Pigment wetting agent
*Emollient : Softens and smoothes the skin
*Masking : Reduces or inhibits the odor or basic taste of the product
*Solvent : Dissolves other substances
*Perfuming : Used for perfume and aromatic raw materials



BENEFITS OF GUERBET C20:
*Emollient, solvent, and moisturizer for all kinds of skin care products
*Provides the skin a soft, smooth appearance
*Ideal solvent to dissolve salicylic acid



CHARACTERISTICS OF GUERBET C20:
*Emollient
*Solubilizer
*Lubricant



WHY DO WE USE GUERBET C20 IN FORMULATIONS?
Why do we use it in formulations?
Guerbet C20 is very useful in formulations.
Guerbet C20 offers emolliency, moisturizing, and lubrication.
Guerbet C20 also helps decrease foam, stabilize emulsions, and is an excellent solvent.



USE AND BENEFITS OF GUERBET C20:
Guerbet C20 is a fatty alcohol, so it can impart a fatty component to the skin, that’s how it helps in keeping skin moisturized.
Guerbet C20 forms a protective layer on the skin, reducing water loss, makes skin soft and smooth in appearance, this process helps skin remain hydrated.
This property is particularly helpful for dry skin.

Guerbet C20 also stabilizes the product and prevents the components from getting separated into its oil and water-based components.
When a product is exposed to higher temperatures or humid conditions, the chances of breaking off an emulsion increase.
So, when an emulsifier is used in any product Guerbet C20 may help to stabilize it further.

Moreover, Guerbet C20 is resistant to hydrolysis, in other words even if it comes in contact with other chemicals it does not destabilize itself.
So, Guerbet C20 can be considered as quite a stable ingredient.
Guerbet C20 also finds its use as a solvent for ingredients in perfumes.

Guerbet C20 can be used as a substitute for silicone in many formulations.
Guerbet C20 is also used specially to dissolve salicylic acid.
Guerbet C20 is used in formulations of creams, lotions, sun care, and other skin and hair care products any beneficial effect, it has a natural fragrance that makes it a unique choice for making fragrant cosmetic.



WHAT DOES GUERBET C20 DO IN A FORMULATION?
*Emollient
*Perfuming
*Solvent



PRODUCTION OF GUERBET C20:
Guerbet C20 is produced by the Guerbet condensation of decyl alcohol.



REACTIONS OF GUERBET C20:
When Guerbet C20 is melted with an alkali it yields octyldodecanoic acid by a dehydrogenation reaction.



IS GUERBET C20 SAFE?
The safety of Guerbet C20 has been reviewed by the Cosmetic Ingredient Review Expert Panel, a group responsible for evaluating the safety and efficacy of skincare and cosmetic ingredients.
In their evaluation, the Expert Panel determined that Guerbet C20 was safe for use in its current indications and concentrations.
This determination was reviewed in 2004 and was reaffirmed.



WHAT ARE THE BEST SKIN CARE PRODUCTS OF 2023?
Now to get a little technical, Guerbet C20 is a branched-chain fatty acid.
Guerbet C20 has a higher molecular weight than other non-volatile alcohols so it doesn’t readily penetrate the skin.
This makes Guerbet C20 a great barrier ingredient.
Guerbet C20 is produced from natural fats and oils through the process of reduction of the fatty acid to produce an alcohol.



REFINED OR UNREFINED, GUERBET C20?
Guerbet C20 only exists as a refined product.



STRENGTHS OF GUERBET C20:
Guerbet C20 is an excellent solvent for salicylic acid.



WEAKNESSES OF GUERBET C20:
Guerbet C20 can be tricky to find.



ALTERNATIVES AND SUBSTITUTIONS OF GUERBET C20:
Before you choose an alternative, you’ll need to determine why Guerbet C20 is used in a formulation.
If Guerbet C20 is being used as an emollient you could try different emollient ingredients like liquid oils, esters, and silicones.



HOW TO WORK WITH GUERBET C20:
Include Guerbet C20 in the oil phase of your formulations; it can be hot or cold processed.



PHYSICAL and CHEMICAL PROPERTIES of GUERBET C20:
Chemical formula: C20H42O
Molar mass: 298.555 g·mol−1
Appearance: yellow oil
Density: 0.84
Melting point: 1 °C (34 °F; 274 K)
Boiling point: 382 °C (720 °F; 655 K)
Refractive index (nD): 1.454
Flash point: 113 °C (235 °F; 386 K)
Melting Point: -1-1ºC(lit.)
Boiling Point: 357.7ºC at 760 mmHg
Flash Point: 113ºC
Molecular Formula: C20H42O
Molecular Weight: 298.54700
Density: 0.838
Molecular Formula: C20H42O
Molar Mass: 298.55

Density: 0.838g/mLat 25°C(lit.)
Melting Point: −1-1°C(lit.)
Boling Point: 234-238°C/33mmHg(lit.)
Flash Point: 113°C
Water Solubility: 10μg/L at 23℃
Solubility: Practically insoluble in water, miscible with ethanol (96 per cent).
Vapor Presure: 0.1Pa at 148.85℃
Appearance: neat
Color: Colourless
pKa: 15.03±0.10(Predicted)
Storage Condition: 2-8°C
Refractive Index: n20/D 1.453(lit.)
MDL: MFCD01310428
Boiling Point: 382°C
Melting Point: 1°C
Solubility: Insoluble in water
Miscible in alcohol

Appearance Form: viscous liquid
Color: colorless
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: -1 - 1 °C - lit.
Initial boiling point and boiling range: 234 - 238 °C at 44 hPa - lit.
Flash point: 188 °C - open cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: < 0,001 hPa at ca.38 °C

Vapor density: No data available
Relative density: 0,84 at 20 °C
Water solubility: 0,0001 g/l at 23 °C - insoluble
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: 241 °C at 1.024 hPa
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Molecular Weight: 298.5
XLogP3-AA: 9.2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1

Rotatable Bond Count: 17
Exact Mass: 298.323565959
Monoisotopic Mass: 298.323565959
Topological Polar Surface Area: 20.2 Ų
Heavy Atom Count: 21
Formal Charge: 0
Complexity: 179
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of GUERBET C20:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of GUERBET C20:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment.
Ensure adequate ventilation.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of GUERBET C20:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of GUERBET C20:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of GUERBET C20:
-Precautions for safe handling:
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of GUERBET C20:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
2-Octyldodecan-1-ol
Other names
2-Octyl-1-dodecanol
2-Octyldodecanol
Eutanol G
Guerbet C20
Isofol 20
Kalcohl 200G
NSC 2405
Exxal 20
Eutanol G
Isofol 20
AI3-19966
JARCOL 1-20
icosan-9-ol
BRN 1763479
Standamul G
JARCOL I-20
Rilanit G 20
Octyldodecanol
UNII-461N1O614Y
Octyl dodecanol
OCTYL DODECANOL
2-Octyldodecanol
2 OCTYL DODECANOL
2-Octyl dodecanol
2-octyl-1-dodecano
2-Octyldodecan-1-ol
2-OCTYL-1-DODECANOL
2-octyl-1-dodecanol
2-Octyl-1-dodecanol
2-octyldodecylalcohol
ISO ARACHIDYL ALCOHOL
1-Dodecanol, 2-octyl-
2-Octyldodecyl alcohol
3-01-00-01844 (Beilstein Handbook Reference)
2-Octyldodecanol
2-Octyldodecyl alcohol
Eutanol G
Eutanol G-PH
Exxal 20
Fine Oxocol 2000
Guerbet C20
Isofol 20
Jarcol I 20
Kalcohl 200G
Kalcohl 200GD
Kollicream OD
NJCOL 200A
NSC 2405
OHV 180
Rilanit G 20
Risonol 20SP
2-Octyl-1-dodecanol
Eutanol G
Standamul G
2-Octyl-1-dodecanol
2-Octyldecanol
2-OctyldodecanolOctyldodecanol
2-Octyldodecyl alcohol
2-Octyldodecan-1-ol
Exxal 20
Michel XO-150-20
Fine Oxocol 2000
Guerbet C20
Isofol 20
Jarcol I 20
Kalcohl 200G
NSC 2405
OHV 180
Rilanit G 20
Risonol 20SP
2-Octyldodecanol
2-Octyldodecyl alcohol
Eutanol G
Eutanol G-PH
Exxal 20
Fine Oxocol 2000
Guerbet C20
Isofol 20
Jarcol I 20
Kalcohl 200G
Kalcohl 200GD
Kollicream OD
NJCOL 200A
NSC 2405
OHV 180
Rilanit G 20
Risonol 20SP
2-Octyl-1-dodec
2-Octyldodecanol
2-Octyldodecyl alcohol
Eutanol G
Eutanol G-PH
Exxal 20
Fine Oxocol 2000
Guerbet C20
Isofol 20
Jarcol I 20
Kalcohl 200G
Kalcohl 200GD
Kollicream OD
NJCOL 200A
NSC 2405
OHV 180
Rilanit G 20
Risonol 20SP
2-Octyl-1-dodecanol
1-Dodecanol, 2-octyl-
Eutanol G
2-Octyldodecyl alcohol
Exxal 20
2-Decyl-1-decanol
Guerbet C20
NJCOL 200A
Octyldodecyl alcohol
Rilanit G 20
2-Octyldodecanol
Eutanol G-PH
Fine Oxocol 2000
Jarcol I 20
Polymol G
OHV 180
Tegosoft G 20
Kollicream OD
Kalcohl 200G
NSC 2405
Isofol 20
Risonol 20SP
Kalcohl 200GD
Eutanol G-JP
2-Octyl-1-dodecanol
Octyldodecanol
2-Octyldodecan-1-ol
2-Octyl-1-dodecanol
5333-42-6
Octyldodecanol
2-Octyldodecanol
1-DODECANOL, 2-OCTYL-
Standamul G
2-Octyl dodecanol
Eutanol G
2-Octyldodecyl alcohol
Isofol 20
Kalcohl 200G
Rilanit G 20
Exxal 20
Octyl dodecanol
2-n-octyl-1-dodecanol
NSC 2405
NSC-2405
461N1O614Y
NCGC00166213-01
Kalcohl 200GD
2-octildodecanol
Guerbet C20
Risonol 20SP
CAS-5333-42-6
Octyldodecanol [NF]
Jarcol I 20
Fine Oxocol 2000
2-Octyldodecane-1-ol
EINECS 226-242-9
BRN 1763479
AI3-19966
UNII-461N1O614Y
OHV 180
2-octyl-dodecanol
Michel XO-150-20
EC 226-242-9
OCTYLDODECANOL [II]
OCTYLDODECANOL [MI]
SCHEMBL4873
OCTYLDODECANOL [INCI]
3-01-00-01844 (Beilstein Handbook Reference)
2-Octyl-1-dodecanol, 97%
CHEMBL1572050
DTXSID3036288
NSC2405
(+/-)-2-OCTYLDODECANOL
2-octyldodecan-1-ol, octyldodecanol
Tox21_112351
Tox21_302294
MFCD01310428
OCTYLDODECANOL [EP MONOGRAPH]
2-OCTYLDODECANOL, (+/-)-
AKOS015912966
Tox21_112351_1
CS-W021736
DB14134
DS-6274
NCGC00166213-02
NCGC00255681-01
BP-30229
FT-0699733
O0429
C20338
D77924
EN300-373383
A870757
SR-01000944811
SR-01000944811-1
Q27258886
Octyldodecanol, European Pharmacopoeia (EP) Reference Standard
Octyldodecanol, United States Pharmacopeia (USP) Reference Standard
Octyldodecanol, Pharmaceutical Secondary Standard; Certified Reference Material

GUM ARABIC
Gum arabic (gum acacia, gum sudani, Senegal gum and by other names) is a natural gum originally consisting of the hardened sap of two species of the Acacia tree, Senegalia senegal and Vachellia seyal.


CAS Number: 9000-01-5
EC Number: 232-519-5
Molecular Formula: C12H36


Gum arabic is a complex mixture of glycoproteins and polysaccharides, predominantly polymers of arabinose and galactose.
Gum arabic is a key ingredient in traditional lithography and is used in printing, paints, glues, cosmetics, and various industrial applications, including viscosity control in inks and in textile industries, though less expensive materials compete with it for many of these roles.


Gum arabic was defined by the 31st Codex Committee for Food Additives, held at The Hague from 19 to 23 March 1999, as the dried exudate from the trunks and branches of Acacia senegal or Vachellia (Acacia) seyal in the family Fabaceae (Leguminosae).
Gum arabic is soluble in water, edible, and used primarily in the food industry and soft-drink industry as a stabilizer, with E number E414 (I414 in the US).

Gum arabic's mixture of polysaccharides and glycoproteins gives it the properties of a glue and binder that is edible by humans.
Other substances have replaced it where toxicity is not an issue, as the proportions of the various chemicals in gum arabic vary widely and make it unpredictable.


Gum Arabic remains an important ingredient in soft drink syrup and "hard" gummy candies such as gumdrops, and marshmallows.
Gum Arabic, also known as acacia gum, is a natural gum obtained from the sap of Acacia senegal and Acacia seyal trees.
Gum arabic is a complex mixture of polysaccharides and glycoproteins that are soluble in water.


Gum arabic (gum acacia, gum sudani, Senegal gum and by other names) is a natural gum originally consisting of the hardened sap of two species of the Acacia tree, Senegalia senegal and Vachellia seyal.
However, the term "gum arabic" does not actually indicate a particular botanical source.


The gum is harvested commercially from wild trees, mostly in Sudan (about 70% of the global supply) and throughout the Sahel, from Senegal to Somalia.
The name "gum Arabic" (al-samgh al-'arabi) was used in the Middle East at least as early as the 9th century.
Gum arabic first found its way to Europe via Arabic ports, and so retained its name.


Gum arabic (GA) is one of the most abundant polysaccharides in nature, and has excellent water solubility and biocompatibility paired with low cost.
If little water is used, after evaporation, the acacia gum functions as a true binder in a paint film, increasing luminosity and helping prevent the colors from lightening.


Gum arabic allows more subtle control over washes, because it facilitates the dispersion of the pigment particles.
In addition, acacia gum slows evaporation of water, giving slightly longer working time.
The addition of a little gum arabic to watercolor pigment and water allows for easier lifting of pigment from paper, thus can be a useful tool when lifting out color when painting in watercolor.


Gum arabic is the gum that is exuded from certain trees, such as the Acacia senegal tree.
Gum arabic's a source of dietary fiber that can dissolve in water.
Don't confuse gum arabic with Acacia rigidula, acai, or cassie absolute (Acacia farnesiana).


These are different plants with different effects.
Gum arabic can be processed in different ways.
Crude gum, for example, may be kibbled, or hammered into small bits.


This form is a popular consumer product and is sold worldwide.
Gum arabic may be further pulverized into a powder resembling flour, which is sold for use in confections, such as for coating the outside of candies.
Gum arabic also may be processed into a spray-dried form, in which kibbled gum is dissolved in hot water and impurities are filtered out.


The liquid is then sprayed into a stream of hot air, evaporating the water and leaving the powdered gum at the bottom of the dryer.
Gum arabic E code is E414.
Gum Arabic is insoluble in oils and many organic solvents and soluble in aqueous ethanol solutions.


Gum Arabic; In the beverage industry, the use of gum arabic is very useful in situations such as stabilizing agent, thickening agent, structure correcting agent, emulsifier and filmmaker remain expensive.
Gum arabic is a chemically carbohydrate polymer.


The energy value of the Gum arabic is very low.
In more detail, Gum arabic is the arabic complex and is a variable mixture of arabinogalactic oligosaccharides, polysaccharides and glycoproteins.
Gum arabic is a kind of natural hydrocolloid made of resin which produced in the Arabian region of Africa.


After drying, Arabic gum is very easy to crumble and deliquate, and will turn into a sticky but odorless colloid after being placed in water.
100% pure and all natural Gum Arabic - Highest quality and largest and the most beautiful Gum Nuggets you can buy on the market.
All Natural gum made of the hardened sap of various species of the acacia tree


Gum Arabic is also known as Arabic Gum, Acacia Gum, Chaar Gund , Meska.
Gum arabic is a soluble fiber obtained from Acacia senegal and Acacia seyal trees grown in sub-Saharan Africa, especially Sudan.
Gum arabic is one of the most important medicinal plant sources used in traditional or alternative medicine.


Gum arabic is a substance that promises as a medicinal plant and has short and long-term health potential that can be developed as future herbal medicines for the treatment of various diseases.
Pharmacologically, Gum Arabic has been confirmed to have various therapeutic effects such as hypoglycemic, antidiabetic, antioxidant, immunomodulator and antiulcer.


Gum Arabic, also known as Gum Acacia, is a tree gum exudate that has been an important commercial ingredient since ancient times.
The Egyptians used Gum Arabic for embalming mummies, and for making paints for hieroglyphic inscriptions.
However, in recent years, a renewed interest in Gum Arabic has occurred, as more articles are published concerning its structure, properties, and novel applications in food and pharmaceuticals.


Gum Arabic is a tree exudate that is obtained mainly from the Acacia Senegal or Acacia Seyal species.
The trees grow widely across the Sahelian belt of Africa, a region of Africa is a 3,860-kilometre arc-like land mass immediately south of the Sahara Desert that stretches east-west from Senegal in the west to Somalia in the east.


Gum Arabic is the resin that oozes from the stems and branches of trees.
Production of Gum Arabic or Gum Acacia is stimulated by `tapping,’ which involves removing sections of the bark, taking care not to damage the tree.
The sticky, gummy substance dries on the branches to form hard nodules which are picked by hand and are sorted according to color and size.


Gum arabic is a dried exudate obtained from the stems and branches of certain species from the Acacia genus.
Given its many desirable properties, safety record and natural origin,
Produced primarily in arid wooded savannas in sub-Saharan Africa, but also in smaller quantities in South Asia and the Arabian Peninsula, gum arabic is consumed predominantly by manufacturers in developed and emerging economies.


Exports of crude and semiprocessed gum arabic almost tripled in the last 25 years, from an annual average of 35,000 tons in 1992–1994 to an annual average of 102,000 tons in 2014–2016.
In addition, exports of processed gum arabic more than tripled, from 17,000 tons to 53,000 tons in the same period.


Export revenues of Gum arabic reached an estimated average of $337 million per year in 2014–2016, 44 per cent of which accrued to crude and semi-processed gum and 56 per cent to processed gum.
Overcoming the uneven distribution of economic gains along the value chain by increasing local processing and ensuring higher compensation for resource-poor gum collectors are among the main challenges faced by producing countries.


Due to its potential to generate foreign exchange reserves, ensure food security, promote sustainable agriculture and forestry, and combat desertification and climate change, gum arabic is a promising commodity for a number of sub-Saharan African countries.
Gum arabic has the potential of playing a critical role in producer countries’ efforts to achieve the Sustainable Development Goals set forth in the 2030 Agenda for Sustainable Development.


This issue of the Commodities at a Glance series explores the economic, social and environmental relevance of the gum arabic sector, with a focus on supply, demand, prices and market organization.
Gum arabic's aim is to present information in a clear, concise and reader-friendly format.


In particular, the report makes an important contribution by constructing a comprehensive and improved dataset on crude and processed gum arabic trade flows.
Gum Arabic, also known as acacia gum, is a natural emulsifier and stabiliser that also gives beverages enhanced mouthfeel and texture.


Gum arabic is derived from the hardened sap of two species of the acacia tree: Senegal and Seyal.
Gum Arabic is a complex of glycoproteins and polysaccharides, which mostly consist of arabinose and galactose.
Gum arabic is the protein fraction that gives the gum surface-active properties allowing it to form a colloidal film around oil droplets to act as an emulsifier and for encapsulating flavour.


Gum Arabic is acid stable and works in a wide pH range, from 2 to 10.
Gum arabic can withstand pasteurization temperatures, although prolonged high heat will denature its protein structure.
From colloidal stability and organoleptic sensory enhancement to mouthfeel improvement Gum Arabic is the all-natural choice for beverage developers.


Gum arabic or gum acacia is a tree exudate obtained from the stems and branches of Acacia senegal.
Gum arabic consists mainly of high molecular weight polysaccharides and their magnesium, calcium and potassium salts which of hydrolysis yield galactose, arabinose, glucuronic acid and rhamnose.


Gum arabic is a purely vegetable product and harmless edible biopolymer.
Gum Arabic from Acacia seyal is sometimes referred to as Talha.
The name “gum arabic” was derived from the shipping of this gum to Europe from Arabian ports in former times.


Although “Arabic” deserves to be capitalized, and “gum Arabic” is often encountered, “gum arabic” is the predominant spelling.
In the food industry, gum arabic is used as a stabiliser, emulsifier and thickener in baking, filling, soft candy, chewing gum and other confectionery and for binding the sweeteners and flavourings in soft drinks.


Gum arabic is derived from the sap of Acacia trees and has been used for centuries in food, art, and medicine offering various health benefits.
Gum arabic provides prebiotic effects and potential disease management agents, as well as stabilizing, emulsifying, and thickening properties for use in the food industry.


Gum arabic is a gum derived from the sap of two species of Acacia trees, namely Senegalia senegal and Vachellia seyal.
Gum arabic’s also known as acacia gum or gum acacia.
This natural complex carbohydrate, Gum Arabic, has been found to possibly reduce body fat percentage when consumed by humans, making it beneficial for health purposes.


Gum arabic is a natural gum also known as acacia gum as it is extracted from two sub-Saharan acacia species: Acacia senegal and Acacia seyal.
Like almost all gums and resins of vegetable origin, Gum Arabic is produced by the plant following a natural process of "gummy" which is activated spontaneously to heal a wound.


Gum arabic, also sometimes called acacia gum or acacia powder, is a fibrous product made from the natural hardened sap of two types of wild Acacia trees.
Around the world, Gum arabic goes by many names, including acacia gum, arabic gum, acacia powder, Senegal gum, Indian gum and others.
Acacia senegal (L.), a tree in the Leguminosae (Fabaceae) plant family, is most commonly used to make Gum arabic products.


Vachellia (Acacia) is another species that produces a dried gum from its trunk and branches.
These trees grow most abundantly in Sudan, where about 50 percent of the world’s Gum arabic is now produced, but are also found in other parts of Africa, such as Kenya, Mali, Niger, Nigeria and Senegal.


What’s interesting about acacia trees is that they produce the most Gum arabic when they experience “adverse conditions,” such as poor soil, drought or high heat.
This actually damages the trees to some degree but causes an increase in the production of arabic gum.


Today, there are many industrial and food-related uses for Gum arabic.
For example, gelatin, modified starch, Gum arabic and pectin are the main types of gums used in many sugary/confectionery products.
Gum arabic tear drops are relatively friable and break cleanly into fragments.


Whole tear drops often have a small cavity in the center.
Powdered gum arabic is odorless, tasteless, and has a white or yellow transparent color and glassy luster.
Gum arabic dissolves slowly in twice its weight and leaves only a slight residue of vegetable debris.


Gum arabic is insoluble in alcohol.
Gum arabic in solution is a yellowish-white viscous, translucent liquid which is slightly acidic.
Gum arabic precipitates abundantly when an equal volume of ethanol is added.


Gum arabic, also known as acacia gum, is a natural plant-derived gum produced from the dried sap of several species of acacia trees.
The most important ones for commercial production are Acacia nilotica, Senegalia (Acacia) senegal and Vachellia (Acacia) seyal.
The major component of gum arabic is arabinogalactan, a bipolymer of arabinose and galactose monosaccharides.


Gum Acacia (Gum Arabic) is a dried gummy exudation of high molecular weight polysaccharides obtained from the stems and branches of Acacia senegal (L.) Willdenow.
Purified and spray dried with the highest emulsifying properties.


Gum Arabic is a Off-white powder.
Gum Arabic is a gummy exudation from the branches of the Acacia Senegal (L.) Willd and other species of the Leguminosae Family.
Gum arabic is also known as Gum Acacia, Kordofan Gum, Gum Senegal, Acacia Vera, Gummi Africanum, Gummae Mimosae, kher, Sudan Gum Arabic, Somali Gum, Yellow Thorn, Mogadore Gum, Indian Gum and Australian Gum.


The variety of names is due to the different places, and types of Acacias, from where the Gum Arabic can be extracted.
Many of these trees behave the same and have similar appearance, differing only in some technical characters.
These Acacias are spiny shrubs or small trees that prefer sandy or sterile regions with a dry climate.


This means that most Acacias can be found in North Africa, particularly in Sudan, and to a lesser degree in the Arabian Peninsula, India, and Australia.
During times of drought, the bark of these trees splits, exuding a sap that dries in small droplets or “tears.”
The colour of these oval “tears” can range from white to shades of orange-red.


They are usually harvested in December, and it usually takes about five weeks.
The masses of gum are then collected while they are still stuck to the tree or after they have fallen on the ground.
Historically, these gum pieces were packed in baskets and very large sacks of tanned leather and then taken on camels and bullocks to trading centers in North Africa.


Nowadays, commercial acacia gum is derived by tapping trees periodically and collecting the sap semi-mechanically.
There are at least three different grades of Gum Arabic available commercially and their quality is distinguished by the colour and character of the collected “tears”.


Even though the structure of Gum Arabic is not completely known, it is basically composed of a high molecular weight polysaccharide that contains residues of neutral sugars and acids.
This mixture of polysaccharides and glycoproteins gives it the properties of a glue and binder that is edible by humans.



USES and APPLICATIONS of GUM ARABIC:
Pyrotechnics uses of Gum Arabic: Gum arabic is also used as a water-soluble binder in fireworks composition.
Used more generously than glair, if a little sugar or honey is put into Gum arabic to keep it from becoming brittle.
The use of Gum Arabic produces a more transparent effect than that of glair, the colour tends to be laid more thinly and to appear richer and darker.


Traditionally used in confectioneries, Gum Arabic is recognized as a key ingredient in beverage production and innovation.
Gum arabic is the most commercially valuable exudate gum, with wide applications in industries as diverse as food and beverages, pharmaceuticals, cosmetics, printing, ceramics, photosensitive chemicals, pyrotechnics, textiles, paper, ink, paints and adhesives.


Gum arabic is used as a basic ingredient of familiar foods such as chewing gum, marshmallows and liquorice.
In brewing, Gum arabic is used as a foam stabiliser and agent to promote the adhesion of foam to glass.
Gum arabic is used as a clarity stabiliser in the chemical treatment of wines.


Gum arabic is widely used by professional bartenders in preparing cocktails.
It is essentially sugar water with the addition of gum arabic for extra body and a pleasing “mouth feel”.
In non-alcoholic beverages, carbonated Ready-to-Drinks (RTDs) and plant-based beverages Gum Arabic, a natural hydrocolloid, is the perfect emulsifier and stabiliser.


In wine Gum Arabic is used to improve mouthfeel and in brewing it helps stabilise beer foam.
In beverages where sugar content is reduced Gum Arabic can be used to minimise the loss of volume and texture while increasing the mouthfeel.
Its many functional properties, including a low calorific value, a neutral taste, and its fibre content, make Gum Arabic the perfect natural, clean label ingredient in beverage applications.


The tasteless and nontoxic properties of gum arabic make it especially useful in the food industry, where it is used as an emulsifier, binding or coating agent, and stabilizer.
Some of Gum arabic's applications include providing texture for gum candies, preventing sugar crystallization, acting as an emulsifier in chocolate, and forming a coating for glazed and filled sweets and cereals.


In the beverage industry Gum Arabic is used to preserve the flavour of cola and citrus beverages, to prevent pulp from sinking to the bottom of fruit drinks, and to stabilize foam in beer.
Gum arabic is high in soluble fibre, and, because it can be fermented, it can be used as a prebiotic.


In traditional medicine, gum arabic has been used to treat diarrhea, catarrh (accumulation of mucus in an airway or body cavity), pain, and wounds.
When the gum is chewed, Gum Arabic reduces bacteria around the teeth and gums and slows the accumulation of plaque.
Modern pharmaceutical applications of Gum arabic include use as an encapsulation agent in medications and as a texturizer for oral medications.


Gum arabic is also used as a fixative in textiles, inks, tempera paints, watercolours, and gilding, and it has applications in photography, pyrotechnics, shoe polish, and ceramic glazing.
Gum arabic is used primarily in the food industry as a stabilizer.


Gum arabic is edible and has E number E414.
Gum arabic is a key ingredient in traditional lithography and is used in printing, paint production, glue, cosmetics and various industrial applications, including viscosity control in inks and in textile industries, though less expensive materials compete with it for many of these roles.


Gum arabic is mainly used in the food industry as an edible stabilizer, emulsifier, viscosifier and excipient.
Gum arabic’s also an important raw material in traditional lithography, paint production, pigment blending, glue making and cosmetics blending.
Gum arabic is also used for medical and cosmetic purposes and can treat diseases such as dysentery and gastroenteritis.


Gum arabic is still more commonly used in Middle Eastern markets.
Gum arabic is used by local communities to protect against hepatic, kidney and cardiac complications in diabetic and chronic renal failure patients.
Ingestion of Gum Arabic can reduce plasma cholesterol concentrations in both humans and animals.


Gum arabic is used as a thickener in the food field such as ice cream, pudding, flavoring, salad dressings, confectionery, beverage mixes.
Gum arabic is used as a thickener in various fields such as ice cream, pudding, aroma capsules, salad dressings, confectionery and beverage mixes.
Gum arabic has many advantages, including the fact that it can be used in multiple ways across different industries such as food, art and crafts.


Gum arabic's thickening properties make this gum beneficial for use in stabilizing emulsions and drugs.
These characteristics create an opportunity to utilize Gum arabic’s health benefits effectively making its presence indispensable within various products and applications of today.


HN version uses of Gum arabic: Beverage, Emulsions, Confectionery and Pharmaceutical,
MM version uses of Gum arabic: Coating, Biding, Glazing, GUmming, Encapsulation, soluble Fiber and bakery
Gum Arabic has been used for centuries for various purposes due to its functional properties.


Gum arabic has been used in pharmaceuticals as a demulcent.
Gum Arabic has been used topically in wound-healing preparations.
Antioxidant, anti-inflammatory, antibacterial (ie, in periodontal disease), and lipidemic effects have been studied; however, robust clinical trials are lacking to support a definitive place in therapy.


Gum arabic has been used since ancient times by human civilizations.
Evidence indicates that Gum arabic was used by ancient Egyptians for medical purposes, as well as to make adhesives.
Ancient Arabic physicians also recognized the utility of this plant-derived product, and used it extensively in their own medical practices millennia later.


In the modern world, gum arabic finds use in a larger number of industries than ever before.
Gum arabic is used to make glue, pharmaceutical drugs, cosmetics, paints, and shoe polish.
Since gum arabic is edible, it is also used to manufacture lickable adhesives, such as stamps and envelopes.


In the food industry, gum arabic is utilized as an emulsifying agent to prepare chewing gum, gummy candies, confectionaries, and icings.
In the painting industry, the binding property of Gum arabic is harnessed to manufacture watercolor paints, and as an additive in ceramic glaze manufacturing.


In the pharmaceutical industry, Gum arabic finds use as a demulcent (a soother for irritated mucous membranes).
Gum arabic is also used in topical ointments that help heal wounds, and as an additive in some cough and gastrointestinal medications.
The plant-based product also finds application in the photography and printing industries, where Gum Arabic is used in preparing photographic emulsions and lithographs.


For artists, Gum Arabic is the traditional binder in watercolor paint and in photography for gum printing, and it is used as a binder in pyrotechnic compositions.
Pharmaceutical drugs and cosmetics also use Gum arabic as a binder, emulsifier, and suspending agent or viscosity-increasing agent.


Wine makers have used gum arabic as a wine fining agent.
Gum arabic is an important ingredient in shoe polish, and can be used in making homemade incense cones.
Gum arabic is also used as a lickable adhesive, for example on postage stamps, envelopes, and cigarette papers.


Lithographic printers employ it to keep the non-image areas of the plate receptive to water.
This treatment also helps to stop oxidation of aluminium printing plates in the interval between processing of the plate and its use on a printing press.
Gum arabic, dried water-soluble exudate that comes primarily from two species of acacia in sub-Saharan Africa, Acacia senegal and A. seyal, and that has numerous applications, particularly in the food industry and in areas such as ceramics, painting, photography, and printmaking.



Humans have in fact used gum arabic for thousands of years; one of its earliest known uses was as an embalming agent in ancient Egypt.
Chemically, gum arabic is a polysaccharide and hydrocolloid substance (a substance that becomes a gel in water); its exact chemical composition differs depending on the acacia species from which it is harvested and possibly the conditions under which the tree is grown.


A natural additive obtained from the bark of the acacia tree, Gum Arabic is colourless, tasteless and odorless and is used in commercial food processing to thicken, emulsify and stabilize foods such as candy, ice cream and sweet syrups.
Gum Arabic is also used in cake decorating to make gum paste.


Gum arabic is stable in acid conditions and is widely used as an emulsifier in the production of concentrated citrus and cola flavor oils for application in soft drinks.
Gum arabic is able to inhibit flocculation and coalescence of the oil droplets over several months and furthermore the emulsions remain stable for up to a year when diluted up to ~ 500 times with sweetened carbonated water prior to bottling.


In the preparation of the emulsion a weighting agent is normally added to the oil in order to increase the density to match that of the final beverage and thus inhibit creaming.
Gum arabic tends to make people feel full, so they might stop eating earlier than they otherwise would.


This might lead to weight loss and reduced cholesterol levels.
Gum arabic is used for high cholesterol, diabetes, irritable bowel syndrome (IBS), and other conditions, but there is no good scientific evidence to support these uses.


Pharmacology uses of Gum Arabic: Gum arabic slows the rate of absorption of some drugs, including amoxicillin, from the gut.
Gum arabic can be used in many industries such as food preparation, cosmetics production and art/crafts manufacturing due to its versatility, something that makes arabic gum particularly valuable on multiple levels.


Gum arabic is a complex carbohydrate extracted from two species of Acacia tree, with many beneficial health effects and uses in various industries.
Stabilizing agent Gum arabic has long been used in enology for its ability to prevent cloudiness, tartaric and color precipitation, and to improve the organoleptic characteristics of wine.


Gum arabic's stabilizing ability is due to its molecular structure consisting of a hydrophilic polysaccharide part and a proteinaceous hydrophobic part.
Due to its dual hydrophobic-hydrophilic nature, Gum Arabic for winemaking also interacts with other substances in wine such as aromatic compounds, polyphenols and the CO2 produced during second fermentation.


Gum arabic's effect on the organoleptic quality of wine are typically an increase in aromatic stability and volume and the reduction astringency.
Gum arabic is soluble in water and is used as a traditional binder for colours, as a light adhesive and to create a craquelé effect.
Gum arabic has long been used in traditional medicine and in everyday applications.


The Egyptians used the material as a glue and as a pain-reliever base.
Arabic physicians treated a wide variety of ailments with the gum, resulting in its current name.
Gum Arabic was used for making emulsions and as an ingredient in compounds for the treatment of diarrhea, catarrh, etc.


Gum arabic is used topically for healing wounds and has been shown to inhibit the growth of periodontic bacteria and the early deposition of plaque.
In addition, Gum Arabic has been one of the ingredients in cough syrups, tinctures, and pill coating from the early 19th century onward.
If these medicinal uses were not enough, Gum Arabic has been used by artists as one of the binding agents in tempera paint and gilding, and watercolours.


In ceramics Gum Arabic is used in glazes in order to help them adhere to the clay before it is fired.
Photographers have used Gum Arabic for gum printing and it is also used to protect and etch an image in lithographic processes, both from traditional stones and aluminium plates.


In addition, Gum Arabic is used as a water-soluble binder in the composition of fireworks (pyrotechnics).
Gum Arabic is also an important ingredient in shoe polish, makes newspaper print more cohesive, and can be used in making homemade incense cones.
Gum Arabic is also used as a lickable adhesive, for example on postage stamps, envelopes, and cigarette papers.


Gum arabic is not only edible but highly nutritious.
During the time of the gum harvest, the denizens of the desert are said to live almost entirely on it, and it has been proved that 6 oz is sufficient to support an adult for 24 hours.


Gum arabic is rumored that the Bushman Hottentots have been known in times of scarcity to support themselves on it for days.
In addition, the food industry has been using Gum Arabic as a demulcent, stabilizer and flavour fixative, for years.
Gum Arabic is an important ingredient in chocolates (M&Ms, etc.), and “hard” gummy candies such as gumdrops and marshmallows.


Gum Arabic is also used as an emulsifier and a thickening agent in icing, fillings, chewing gum and other confectionery treats.
More generally, Gum Arabic gives body and texture to processed food products.
Even wine makers have used Gum arabic as a wine fining agent.


Probably the most interesting use for Gum arabic is as part of soft drink syrups.
It binds the sugar to the drink and avoids Gum Arabic from crystallizing on the bottom.
Because Gum Arabic also reduces the surface tension of liquids, it is usually responsible for increased foaming in carbonated beverages.


This can be exploited in the Diet Coke and Mentos Eruption, where a Mentos mint is thrown into a bottle of Diet Coke (or Pepsi) which causes the beverage to spray out of its container.
It really does help that Gum arabic is not toxic!


-Food uses of Gum arabic:
Gum arabic is used in the food industry as a stabiliser, emulsifying agent, and thickening agent in icing, fillings, soft candy, chewing gum, and other confectionery, and to bind the sweeteners and flavourings in soft drinks.
A solution of sugar and gum arabic in water, gomme syrup, is sometimes used in cocktails to prevent the sugar from crystallising and provide a smooth texture.

Gum arabic is a complex polysaccharide and soluble dietary fibre that is generally recognized as safe for human consumption.
An indication of harmless flatulence occurs in some people taking large doses of 30 g (1 oz) or more per day.
Gum arabic is not degraded in the intestine, but fermented in the colon under the influence of microorganisms; it is a prebiotic (as distinct from a probiotic).


-Painting and art uses of Gum Arabic:
Gum arabic is used as a binder for watercolor painting because it dissolves easily in water.
Pigment of any color is suspended within the acacia gum in varying amounts, resulting in watercolor paint.
Water acts as a vehicle or a diluent to thin the watercolor paint and helps to transfer the paint to a surface such as paper.
When all moisture evaporates, Gum arabic typically does not bind the pigment to the paper surface, but is totally absorbed by deeper layers.


-Ceramics uses of Gum arabic:
Gum arabic has a long history as additives to ceramic glazes.
Gum arabic acts as a binder, helping the glaze adhere to the clay before it is fired, thereby minimising damage by handling during the manufacture of the piece.

As a secondary effect, Gum Arabic also acts as a deflocculant, increasing the fluidity of the glaze mixture, but also making it more likely to sediment out into a hard cake if not used for a while.
The gum is normally made up into a solution in hot water (typically 10–25 g/L; ¼ to ½ oz per pint), and then added to the glaze solution after any ball milling in concentrations from 0.02% to 3.0% of gum arabic to the dry weight of the glaze.

On firing, Gum Arabic burns out at a low temperature, leaving no residues in the glaze.
More recently, particularly in commercial manufacturing, gum arabic is often replaced by more refined and consistent alternatives, such as carboxymethyl cellulose.


-Photography uses of Gum Arabic:
The historical photography process of gum bichromate photography uses gum arabic mixed with ammonium or potassium dichromate and pigment to create a coloured photographic emulsion that becomes relatively insoluble in water upon exposure to ultraviolet light.
In the final print, the acacia gum permanently binds the pigments onto the paper.


-Food Industry uses of Gum Arabic:
In the food sector, Gum arabic functions as a thickener, emulsifier and stabilizer similar to xanthan gum.
Gum Arabic is seen in many items such as icings, fillings for candy that’s soft plus chewing gums.

Gum Arabic serves as a gluten-free binder and prebiotic ingredient across some prepackaged products.
Gum arabic has an array of uses including being used like Gomme syrup inside beverages where it helps stop sugar from crystallizing while giving off smooth texture at the same time.


-Printmaking uses of Gum Arabic:
Gum arabic is also used to protect and etch an image in lithographic processes, both from traditional stones and aluminum plates.
In lithography, Gum Arabic by itself may be used to etch very light tones, such as those made with a number-five crayon.

Phosphoric, nitric, or tannic acid is added in varying concentrations to the Gum arabic to etch the darker tones up to dark blacks.
The etching process creates a Gum Arabic adsorb layer within the matrix that attracts water, ensuring that the oil-based ink does not stick to those areas.
Gum arabic is also essential to what is sometimes called paper lithography, printing from an image created by a laser printer or photocopier.


-Art and Crafts uses of Gum Arabic:
Gum arabic, or arabic gum, has a long tradition in art and craft applications.
Gum arabic is utilized as an emulsion when painting with watercolors to allow for greater control over the washes while extending the workability period.
In ceramic crafting glazes are enhanced by mixing Gum arabic into hot water prior to being added to it, which creates a more efficient solution.


-Pharmaceutical and Cosmetic Applications of Gum Arabic:
Gum arabic is widely used for its stability, emulsifying powers and thickening abilities in pharmaceuticals as well as cosmetics.
Gum arabic can also be found employed in biomedical fields where it helps control drug delivery too.
In the beauty industry, glycerin works to stabilize creams and shampoos giving them a pleasant silky finish while lotions benefit from added smoothness with facial masks or face powders taking advantage of Arabic gum's adhesive properties.



ECONOMIC AND CULTURAL SIGNIFICANCE OF GUM ARABIC:
Gum Arabic forms an important part of the economic revenues for a number of African nations.
Sudan, the largest exporter of gum arabic on the continent and in the world, exported nearly 50,000 metric tons of this plant-based product in 2012 alone.
In 2011, the country earned a staggering revenue of $81.8 million by selling 45,633 metric tons of gum arabic, a huge jump from the $23.8 million earned the previous year from an export of 18,202 tons of gum arabic.
China, the U.S.A., India, and the U.K. serve as the chief markets for Sudan’s gum arabic exports.



HERE ARE SOME OF THE FUNCTIONALITIES AND USES OF GUM ARABIC:
-Emulsifier and Stabilizer:
Gum Arabic has excellent emulsifying properties, which means it can help mix two or more typically immiscible substances, such as oil and water.
Gum arabic is often used in the food and beverage industry to stabilize emulsions, preventing separation and enhancing the texture and mouthfeel of products like soft drinks, syrups, and ice creams.


-Thickening and Binding Agent:
Gum arabic acts as a thickener in food and pharmaceutical applications.
Gum Arabic forms a viscous solution when mixed with water, creating a gel-like consistency.
Gum arabic is commonly used in the production of candies, confectionery, and dessert toppings to provide the desired texture.
Gum arabic can also act as a binding agent, helping ingredients stick together in products like tablets and powders.


-Encapsulation:
Gum Arabic is used in encapsulation processes to create microcapsules that can protect sensitive ingredients such as flavors, fragrances, and pharmaceuticals.
These microcapsules help to stabilize and control the release of the encapsulated substances.


-Dietary Fiber:
Gum Arabic is a source of dietary fiber and can be used to increase the fiber content in food products.
Gum arabic is considered a prebiotic fiber, which means it can serve as a food source for beneficial gut bacteria.


-Film-Forming Agent:
Gum Arabic can form a thin, transparent film when dried, which makes it useful as a coating material for various purposes.
Gum arabic is applied to candies, chocolates, and nuts to provide a glossy appearance, prevent moisture loss, and enhance shelf life.


-Pharmaceutical Applications:
Gum Arabic is used in the pharmaceutical industry as an excipient in tablet formulations.
Gum Arabic can act as a binder, disintegrant, and sustained-release agent.
Gum Arabic is a dried gummy exudation of high molecular weight olysaccharides from the Stems and Branchese of Acacia Segenal (L.) Willdenow HN and Acacia Seyal (fam. Leguminosae) MM



GUM ARABIC IS USED TO HELP STABILIZE PRODUCTS INCLUDING:
*A wide variety of desserts and baking ingredients
*Dairy products like ice cream
*Syrups
*Hard and soft candies
*Ink, paint, watercolors, and photography and printing materials
*Ceramics and clay
*Stamps and envelopes
*Shoe polish
*Cosmetics
*Firworks
*Herbal medicines, pills and lozenges
*Emulsions that are applied to the skin



WHAT TYPE OF ORGANIC MOLECULE IS GUM ARABIC?
Gum arabic is made of a mixture of glycoproteins, a class of proteins that have carbohydrate groups attached to the polypeptide chain, and polysaccharides, a carbohydrate whose molecules consist of a number of sugar molecules bonded together.
Gum arabic also includes oligosaccharides, another type of carbohydrate.

Additionally, gums collected from acacia trees are a source of natural sugar compounds called arabinose and ribose, which were some of the first concentrated sugars to be derived from plants/trees.
The exact chemical composition of Gum arabic varies from product to product, depending on its source and the climate/soil conditions in which it was grown.



HEALTH BENEFITS OF GUM ARABIC:
*Gum arabic crystals
Gum arabic is beneficial for a variety of health issues, having prebiotic properties and offering dietary fiber.
Research shows that Gum Arabic can be used to treat medical conditions such as sickle cell anemia (especially helpful for those with the disorder), rheumatoid arthritis, metabolic disorders, periodontitis and gastrointestinal problems to kidney diseases.

It's ability to act both as a source of nourishment while also promoting positive microorganisms makes Gum arabic ideal when looking for ways to improve your overall wellbeing.

*Prebiotic Effects
Gum arabic is a complex carbohydrate that has been shown to act as an effective prebiotic, helping to nourish beneficial bacteria in the gut and stimulating their growth.

This leads to greater production of short-chain fatty acids, which come with various health benefits including improved gastrointestinal function and immune system support.
Overall well-being can also be seen from consuming this particular type of prebiotic due to its potential role in contributing towards better digestion on a whole.

Examples such as Inulin, Fructooligosaccharides (FOS) and Galactooligosaccharides (GOS), all join Gum Arabic when referring to substances aiding healthy microbe populations within our bodies for increased general wellness effects!

*Disease Management
For improved outcomes when using gum arabic therapeutically, it is recommended to focus on nanofomulation-based drug delivery systems paired with appropriately selected doses relative to each individual disease being treated.

Also suggested is that extracting active compounds from this material can offer additional advantages in management of ailments, which drives research efforts looking at its possible medicinal uses over time.

Gum arabic presents itself notably promising due to many studies showing positive results toward alleviating painful symptoms across multiple illnesses yet more knowledge about how exactly it works needs to be acquired through investigation before any definitive conclusions are drawn or widespread applications made available medically speaking by governing bodies worldwide making this material worthy under close consideration while also excitingly encouraging ongoing development initiatives too!



CHEMICAL AND MOLECULAR STRUCTURE OF GUM ARABIC:
Gum arabic consists mainly of calcium, magnesium and potassium salts which yield arabinose, galactose, rhamnose, and glucuronic acid after hydrolysis.
Chemical compositions of Gum Arabic may vary slightly with the source, climate, season, and age of the tree.
Acacia Senegal and Acacia Seyal both contain the same carbohydrate residues.

However, Acacia Seyal gum has lower rhamnose and glucuronic acid contents, and higher arabinose and glucuronic acid contents than the gum derived from Acacia Senegal.
The amino acid compositions are similar in both gums, with hydroxyproline and serine being the major constituents.

Both gums from the Acacia and Acacia Seyal display similar features regarding high-weight molecular mass distributions.
However, the molecular mass of gum from Acacia Seyal is higher than the gum of Acacia Senegal, with an average molecular mass of 380,000 and 850,000, respectively.



PROPERTIES OF GUM ARABIC:
Gum arabic readily dissolves in water to give clear solutions ranging in colour from very pale yellow to orange-brown and with a pH of ~ 4.5.
The highly branched structure of Acacia Senegal gum gives rise to compact molecules with a relatively small hydrodynamic volume and as a consequence gum solutions only become viscous at high concentrations.
A comparison of the viscosity of the gum with xanthan gum and sodium carboxymethylcellulose, which are common thickening agents.

It is seen that even 30% gum arabic solutions have a lower viscosity than 1% xanthan gum and sodium carboxymethylcellulose at low shear rates.
In addition, while gum arabic is Newtonian in behaviour with its viscosity being shear rate independent, both xanthan gum and sodium carboxymethyl cellulose display non-Newtonian shear thinning characteristics.



HEALTH BENEFITS OF GUM ARABIC:
Gum arabic is a rich source of dietary fibers and in addition to its widespread use in food and pharmaceutical industries as a safe thickener, emulsifier, and stabilizer, it also possesses a broad range of health benefits that have been evidently proved through several in vitro and in vivo studies.

Gum arabic is not degraded in the stomach, but fermented in the large intestine into a number of short chain fatty acids.
Gum Arabic is regarded as a prebiotic that enhances the growth and proliferation of the beneficial intestinal microbiota and therefore its intake is associated with many useful health effects.

These health benefits include:
*Improved absorption of calcium from the gastrointestinal tract
*Anti-diabetic
*Anti-obesity (gum arabic lowers the body mass index and body fat percentage)
*Lipid lowering potential (gum arabic decreases total cholesterol, LDL, and triglyceride)
*Antioxidant activities
*Kidney and liver support
*Immune function via modulating the release of some inflammatory mediators
*Prebiotic improving the intestinal barrier function, preventing colon cancer, and alleviating symptoms of irritable bowel diseases



ACACIA TREES AND GUM ARABIC PRODUCTION:
Gum arabic, also known as acacia gum and sourced from Acacia Senegal and Acacia Seyal trees, has been an important commodity since ancient times.
Gum arabic occurs as a sticky liquid that oozes from the stems and branches of acacia trees (Acacia senegal and A. seyal) which grow across the Sahelian belt of Africa, principally Sudan.

Gum arabic is obtained through a process of tapping that carefully removes sections of bark to prevent damage being done to the tree itself.
This produces sticky nodules, Gum Arabic, which are then collected manually based on coloration or size.
The molecular mass for gum arabic produced by each species differs somewhat. With average values at 240 kDa (Acacia seyal) and 580 kDa (Acaasia senegal).

Differences can be observed in their compositions where Acaicia Seyal contains lower concentrations of rhamnose and glucuronic acid compared to its counterpart’s higher levels of arabinse glucose content.
Overall these qualities continue making this substance highly sought after internationally – allowing certain African countries significant revenues generated via exports.



CHEMICAL COMPOSITION OF GUM ARABIC:
The different molecular weights of Gum arabic are directly related to its composition.
Gum arabic makeup includes minerals such as calcium and magnesium salts along with a biopolymer made up of arabinose and galactose monosaccharides - all depending upon factors like tree species or climate/season.
Owing to Gum arabic structure offering potential health benefits, it is employed for various functions due to its versatility.



DOES GUM ARABIC DISSOLVED IN WATER?
Gum arabic contains galactose, arabinose, glucuronic acid, and rhamnose.
In hot and cold water, gum arabic is fully soluble, giving a viscous solution.
Heating up a gum arabic solution to the boiling point, however, will make it darken and change its adhesion properties.



WHY IS IT CALLED GUM ARABIC?
Gum arabic is a complex mixture of glycoproteins and polysaccharides.
This is the original source of ribose and arabinose sugars, both of which have been first found and derived from it, and are also named after it.
This gum arabic is primarily used as a stabiliser in the food industry.



WHICH BIOMOLECULE IS GUM ARABIC?
Gum Arabic is a normal branched-chain multi-functional hydrocolloid with a complex of calcium, magnesium, and potassium that is strongly neutral or mildly acidic, arabinogalactan proteins.



PRODUCTION OF GUM ARABIC:
While Gum arabic has been harvested in Arabia and West Asia since antiquity, sub-Saharan acacia gum has a long history as a prized export.
The gum exported came from the band of acacia trees that once covered much of the Sahel region, the southern littoral of the Sahara Desert that runs from the Atlantic Ocean to the Red Sea.

Today, the main populations of gum-producing Acacia species are found in Mauritania, Senegal, Mali, Burkina Faso, Niger, Nigeria, Chad, Cameroon, Sudan, Eritrea, Somalia, Ethiopia, Kenya, and Tanzania.
Acacia is tapped for gum by stripping bits off the bark, from which gum then exudes.

Traditionally harvested by seminomadic desert pastoralists in the course of their transhumance cycle, acacia gum remains a main export of several African nations, including Mauritania, Niger, Chad, and Sudan.
Total world gum arabic exports were estimated in 2019 at 160,000 tonnes, having recovered from 1987 to 1989 and 2003–2005 crises caused by the destruction of trees by the desert locust



COMPOSITION OF GUM ARABIC:
Arabinogalactan is a biopolymer consisting of arabinose and galactose monosaccharides.
It is a major component of many plant gums, including Gum arabic.
8-5' Noncyclic diferulic acid has been identified as covalently linked to carbohydrate moieties of the arabinogalactan-protein fraction.



HISTORY OF GUM ARABIC:
POLITICAL ASPECTS OF GUM ARABIC:
WEST AFRICA:
In 1445, Prince Henry the Navigator set up a trading post on Arguin Island (off the coast of modern Mauritania), which acquired Gum arabic and slaves for Portugal.

With the merger of the Portuguese and Spanish crowns in 1580, the Spaniards became the dominant influence along the coast.
In 1638, however, they were replaced by the Dutch, who were the first to begin exploiting the Gum arabic trade.
Produced by the acacia trees of Trarza and Brakna, this Gum Arabic was considered superior to that previously obtained in Arabia.
By 1678, the French had driven out the Dutch and established a permanent settlement at Saint Louis at the mouth of the Senegal River.

Gum Arabic came to play an essential role in textile printing and therefore in pre-industrial economies of France, Great Britain and other European countries.
Throughout the 18th century, their competition over the commodity was so fierce, that some have referred to it as the gum wars.

For much of the 18th and 19th centuries, gum arabic was the major export from French and British trading colonies in modern Senegal and Mauritania.
West Africa had become the sole supplier of world Gum arabic by the 18th century, and its export at the French colony of Saint-Louis doubled in the decade of 1830 alone.

A threat to bypass Saint-Louis and taxes by sending gum to the British traders at Portendick, eventually brought the Emirate of Trarza into direct conflict with the French.
In the 1820s, the French launched the Franco-Trarzan War of 1825.

The new emir, Muhammad al Habib, had signed an agreement with the Waalo Kingdom, directly to the south of the river.
In return for an end to raids in Waalo territory, the emir took the heiress of Waalo as a bride.
The prospect that Trarza might inherit control of both banks of the Senegal struck at the security of French traders, and the French responded by sending a large expeditionary force that crushed Muhammad's army.

The war incited the French to expand to the north of the Senegal River for the first time, heralding French direct involvement in the interior of West Africa.
Africa continued to export gum arabic in large quantities—from the Sahel areas of French West Africa (modern Senegal, Mauritania, Mali, Burkina Faso, and Niger) and French Equatorial Africa (modern Chad) as well as British-administered Sudan, until these nations gained their independence in 1959–61.

SUDAN:
Since the 1950s, the global supply of gum arabic has been dominated by Sudan.
In the early 2020s, about 70% of the global supply has been sourced from Sudan, with approximately 5 million Sudanese people (more than 10 percent of a country's population) being directly or indirectly dependent on gum arabic for their livelihoods.

After market reforms in 2019, official figures showed that Sudan's exports of gum arabic were at about 60,000 tonnes in 2022, but exact numbers are difficult to ascertain because some production is in regions that are hard to access.
Before the reforms, the production of gum arabic was heavily dominated by the Sudanese government and in some periods there were attempts of using its importance to the global market as a leverage against other countries.

Since the 2023 Sudan conflict, the export of gum arabic has been interrupted, causing a crash in its price in Sudan because of a reduced ability to export the product, whereas international companies that rely on it are attempting to diversity the supply chain of gum arabic and find alternative ingredients that can be used as a replacement.



SYMBOLIC VALU OF GUM ARABIC:
In the works of English playwright William Shakespeare, Dutch poet Jacob Cats and other European poets of the 13th to 17th centuries, gum arabic represented the "noble Orient".
In the Sahel, Gum Arabic is a symbol of the purity of youth.



HARVESTING AND PROCESSING OF GUM ARABIC:
Gum arabic is harvested at the end of the rainy season in sub-Sarahan Africa, being collected from wild mature A. senegal and A. seyal trees that are usually between 5 and 25 years old.
Incisions are introduced in the stems and branches of the trees, and the surrounding bark is stripped.
Gum Arabic seeps into the incisions within several weeks.

As Gum Arabic dries upon exposure to air, it forms a nodule.
Every two to four weeks, the nodules are removed from the trees and dried completely in the sun.
Once dried, they are visually inspected and sorted by size.
At this stage, Gum arabic may be sold as a crude (unprocessed) substance, or it may be refined and later sold as processed gum arabic.



ECONOMIC AND POLITICAL SIGNIFICANCE OF GUM ARABIC:
Most gum arabic used worldwide comes from A. senegal, within the so-called “gum belt” of Africa’s Sahel, the semiarid region of western and north-central Africa that extends from Senegal eastward to Sudan.
This type of gum arabic, sometimes referred to as hashab gum, is hard and of high quality.

Talha gum from A. seyal, on the other hand, is of lower quality and friable (brittle).
Much of the crude gum produced in these regions is exported to France, Germany, India, the United States, and the United Kingdom.
Given its versatility and worldwide use, gum arabic is considered an important component of economic development for countries within the Sahel.

In particular, during Gum arabic harvesting season, it provides work opportunities for individuals in local communities.
Moreover, exports of Gum arabic have risen steadily since the 1990s.
Crude and semi-processed gum exports, for example, amounted to about 35,000 tons each year between 1992 and 1994, and in 2017–19 this figure was about 80,000 tons annually.

Over that same period of time, export of processed gum arabic also expanded significantly.
Export prices likewise have increased steadily since the 1990s, filling an important role in the economic growth of countries that produce gum arabic.
Because there are few satisfactory substitutes for gum arabic, it has been used by governments of producing states for bargaining when faced with sanctions.

Such was the case in the 1990s and 2000s, when Sudan faced sanctions for supporting terrorism.
Political unrest in the countries that produce gum arabic may further disrupt harvest and exportation, leading to lost revenue for producers and limited supply for consumers.

In 2023, war between the Sudanese army and a paramilitary group resulted in the deaths of thousands and the displacement of millions.
The conflict and loss of life caused the price of Sudanese gum arabic to fall by 60 percent.
Such unreliability in the supply chain has given impetus to the development of a viable replacement for gum arabic.



HEALTH BENEFITS OF GUM ARABIC:
Health Benefits of Gum Arabic or Gum Acacia
While Gum arabic has been investigated extensively for its properties as a hydrocolloid with several food applications, it has also been the subject of more recent investigation for its ability to improve human health.

Because Gum Arabic can reach the large intestine and resist digestion in the small intestine, it can be categorized as a non-digestible carbohydrate or dietary fiber.
Gum Arabic can also be categorized as a prebiotic.

In the large intestine, gum Arabic is fermented by bacteria that produce short-chain fatty acids (SCFA), particularly propionic acid, as by-products of fermentation that are associated with significant improvements to human health.

*Bifidogenic:
Fermentation of Gum Arabic has shown to selectively increase the proportions of lactic acid-producing bacteria and bifidobacteria in study subjects.
Gum arabic also augments the water content of stools and increases stool output.
Further, evidence suggests that gum arabic acts as a prebiotic as doses of 10g/day, and can be consumed with at even higher daily doses without any adverse gastrointestinal issues.

Gum Arabic is known to feed several different strains of indigenous bifidobacterium including B. longum, and showed that it could increase Bifidobacterium animalis subsp. lactis significantly better than both inulin and glucose.

*Prebiotic:
Gum Arabic can selectively raise the proportions of lactic acid bacteria and bifidobacteria in healthy subjects.
Gum arabic is fermented slowly, with digestibility around 95%.
Gum Arabic also increases stool output by augmenting the water content of stools.

It is well tolerated at high daily doses and has shown that Gum arabic can be consumed without any adverse intestinal events.
Evidence demonstrates that Gum arabic acts as a prebiotic at a dose of 10 g/day.

*SCFAs:
Other investigations have shown that bacterial fermentation with Gum Arabic produced more SCFAs such as butyrate and propionate in vitro and in vivo than other well-known prebiotics such as pectin, inulin, and alginate.
This is unequivocal evidence that gum arabic is a non-digestible, prebiotic polysaccharide.

*Anti-Diabetic:
Other studies found that microbial SCFA production (and viscosity) was significantly increased after the addition of gum arabic to foods, and further suggested that it also reduced postprandial glycemic response having a homeostatic effect on diabetes via increased acetic acid production.
Therefore, the simple addition of gum arabic improved foods metabolically for human use.

*Nephroprotective:
Gum Arabic increases creatinine clearance, enhances renal excretion of antidiuretic hormones, decreases plasma phosphate concentration, enhances renal secretion of antidiuretic hormone, and is used as a treatment for chronic and end-stage renal disease in Middle Eastern countries.
The effects of Gum Arabic on plasma phosphate concentration, blood pressure, and proteinuria may prove beneficial in chronic renal failure (CRF) and diabetic nephropathy.

Gum arabic moderately reduces histological and biochemical markers after acute gentamycin nephrotoxicity.
Gum Arabic may also serve as a treatment for a renal disease as well due to its ability to trap bile salts in conjunction with its relatively high effect on butyrate production which has shown to suppress the production of TGF-beta1 cytokines.

*Anti-carcinogenic:
Angiogenins are angiogenetic factors upregulated by tumor cells, and are involved in the vascularization and growth of tumors.
Angiogenins are upregulated in cancer cells by numerous tissues that include colon, stomach, liver, pancreas, uterus, breast, ovary, prostate, bladder, kidney, and brain.

Angiogenins are also found up-regulated in leukemia, osteosarcoma, lymphoma, melanoma, and Wilms tumor.
According to study, Gum arabic produced a “profound inhibitory effect on angiogenin suppression.

*Anti-Obesigenic:
Gum Arabic significantly reduced the BMI and body fat percentage in a two-arm randomized, placebo-controlled, double-blind trial of healthy adult females.
Authors of the study suggest that Gum Arabic should be investigated further as a treatment for obesity.
However, Gum Arabic was noted that common side effects included preliminary bloating and diarrhea.

*Lower Cholesterol:
In other studies, Gum Arabic + apple fiber were found to lead to a significant reduction of total serum cholesterol concentration, especially the LDL fractions in men with high cholesterol.

*Ulcerative Colitis:
Gum arabic may serve as a treatment for ulcerative colitis due to its ability to increase the SCFAs butyrate production and its trophic effects on the gut membrane, as well as its ability to reduce the duration and incidence of diarrhea



COMMON FOOD APPLICATIONS OF GUM ARABIC:
Here’s a fun fact:
When the US imposed sanctions on Sudan over the government’s actions in Darfur in 2000, it stopped all imports except one: Gum Arabic.
The government feared that stopping the imports on gum arabic would have too severe an impact on the US food industry.
Gum Arabic is one of the most ubiquitous ingredients in consumer products— ranging from Coca-Cola to shoe polish, to pharmaceuticals and confectionaries.

*Confectionary Applications:
The primary application of gum arabic is in the confectionery industry, used in a variety of products including gums, pastilles, marshmallows, and toffees.
Traditional wine gums also incorporated gum arabic at high concentrations and added wine for flavor.

*Beverages:
Gum arabic is stable in acid conditions.
For this reason, gum arabic is often used as an emulsifier in the production of concentrated flavor oils, such as those found in soft drinks.
Gum Arabic inhibits the coalescence of oil droplets, keeping emulsions stable for up to a year.

*Dietary Fiber Fortification:
In regulatory terms, dietary fiber refers to carbohydrate polymers which are neither digested nor absorbed in the small intestine, with polymerization of above three.

In other words, monosaccharides and disaccharides are inherently excluded from meeting requirements of the definition.
Gum arabic meets the requirements from a scientific point of view and has shown beneficial physiological effects.
Utilizing gum arabic in place of other ingredients in commercial recipes can help decrease net carbs in products and improve nutritional value.



OBJECTIVE, ORIGIN AND SCOPE OF APPLICATION OF GUM ARABIC:
Gum arabic is a gummy exudation which hardens in air and flows naturally or through cuts made in tree trunks and branches of the L. Acacia senegal L. Willdenow and other African Acacia species.
Gum arabic is composed of spherical tear drop-shaped globules, or sometimes irregular oval shapes with a diameter of 1-3 cm.
Gum arabic exists in powder form or in colloidal solution.

Gum arabic is used to improve the stability of bottled wine.
Gum arabic is composed of a polysaccharide rich in galactose and arabinose along with a small protein fraction which gives its stabilizing power with respect to the precipitation of coloring substances and iron or copper breakdown.
There are limits imposed on the quantity of gum arabic used in wine.



GEOGRAPHIC DISTRIBUTION OF GUM ARABIC:
Gum Arabic is harvested from acacia trees growing throughout the Sahel eco-region (a transition zone between the northern Sahara Desert and the southern belt of savanna).
This area is seen stretching all the way from Senegal in West Africa to Somalia in East Africa, including the African countries of Eritrea, Chad, Mali, Burkina Faso, Mauritania, Cameroon, Kenya, Niger and Nigeria and Sudan.
However, most of the production of Acacia, nearly 80% of the global total, is concentrated in Sudan.



CULTIVATION AND PRODUCTION OF GUM ARABIC:
The hardened sap of the acacia plant is collected during the middle of the rainy season (usually in July) by cutting holes into the bark of the Acacia senegal and tapping its sap, which is often known as Senegal gum.
In the case of Acacia seyal, the other species of Acacia from which Seyal gum is collected, collection is sourced from the natural exudation of the plant.

This extracted raw gum arabic is subsequently processed, and is then ready to be exported by the beginning of the dry season (usually in November).
Gum arabic exports form a major source of income for many African countries, especially Sudan, Niger, Chad, and Mauritania.
As per estimates from 2007, 95% of the world’s gum arabic exports were from three countries.
These were Sudan, Nigeria and Chad, and, in 2008, 60,000 metric tons of this plant-based product was exported from the African continent alone.



PHYSICAL and CHEMICAL PROPERTIES of GUM ARABIC:
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point:
No data available
Initial boiling point and boiling range:
No data available Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: ca.1,4 g/cm3
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
CAS number: 9000-01-5
EC number: 232-519-5
Grade: Ph Eur,BP
HS Code: 1301 20 00
Density: 1.4 g/cm3
pH value: 5 (100 g/l, H₂O, 20 °C)
Bulk density: 400 kg/m3
Solubility: 500 g/l
Density: 1.35-1.49
Molecular weight/ Molar mass: ≈ 0.25×106
Boiling point: > 250ºC
Melting point: 0 – 100oC
Odour: Odourless
Appearance: Glassy appearance
pH: 4.5
Emulsifying properties: 30%
Solubility: The solubility in water is 43–48%



FIRST AID MEASURES of GUM ARABIC:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of GUM ARABIC:
-Environmental precautions
Do not let product enter drains.
-Methods and materials for containment and cleaning up
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of GUM ARABIC:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media.
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of GUM ARABIC:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Respiratory protection
Recommended Filter type: Filter type P1
-Control of environmental exposure
Do not let product enter drains.



HANDLING and STORAGE of GUM ARABIC:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of GUM ARABIC:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Acacia Gum
Arabic Gum
Gum arabic (Acacia senegal)
Gum arabic (Acacia seyal)
Acacia, Arabic gum
Acacia senegal (L.) Willd.
Senegalia senegal (L.) Britton
Acacia arabica, Acacia gum
Acacia vera
Egyptian thorn
Gum arabic
Gum senegal
Gummae mimosae
Gummi africanum
Kher
Somali gum
Sudan gum arabic
Yellow thorn
Gum arabic (Acacia senegal) Gum hashab
kordofan gum
Gum arabic (Acacia seyal) Gum talha
Acacia gum
Arabic gum



Gum arabic
HALAMID(CHLORAMINE T); Tosylchloramide sodium; Tosilcloramida sodica (Spanish); Aktiven; Chloraseptine; Tochlorine; tolamine; Chlorazene; Chlorazone; Clorina; Halamid; Mianine; (N-Chloro-p-toluenesulfonamido) sodium; Sodium p-Toluenesulfonchloramide; p-Toluenesulfonchloramide Sodium Salt cas no: 127-65-1
GÜL AROMASI
rose flavor ; appy rose; rose flavor for confectionery; rose flavor natural
Gül Ekstrakt
Rose Extract ;;rosa canina l. bud extract; dog-brier bud extract; extract of the buds of rosa canina, rosaceae; rosa ciliatosepala bud extract; rosa corymbifera bud extract;rose bud extract cas no:84696-47-9
Gümüşdüğme Ekstrakt
Chrysanthemum parthenium extract; aphanostephus pinulensis extract; extract of the herb of the feverfew, chrysanthemum parthenium, asteraceae; feverfew extract; matricaria parthenium extract; pyrethrum parthenium extract; tanacetum parthenium extract cas no:89997-65-9
GYMNEMA SYLVESTRE EXTRACT

Gymnema Sylvestre Extract is a natural botanical ingredient derived from the leaves of the Gymnema sylvestre plant, known for its anti-diabetic, anti-inflammatory, and appetite-suppressing properties.
Gymnema Sylvestre Extract is widely recognized for its ability to reduce sugar absorption, promote healthy glucose levels, and support weight management, making it a valuable ingredient in dietary supplements and wellness formulations.
This versatile extract offers both therapeutic and wellness benefits, helping to support healthy blood sugar levels, reduce sugar cravings, and maintain metabolic balance.

CAS Number: 1404-22-4
EC Number: 215-757-3

Synonyms: Gymnema Sylvestre Extract, Gurmar Extract, Gymnema Leaf Extract, Gymnemic Acid, Gymnema Herbal Extract, Gymnema Phytoextract, Gymnema Sylvestre Bioactive, Gymnema Sylvestre Phytocomplex, Gurmar Herbal Extract, Gymnema sylvestre Active, Sugar Destroyer Extract



APPLICATIONS


Gymnema Sylvestre Extract is extensively used in dietary supplements aimed at promoting healthy blood sugar levels and supporting glucose metabolism.
Gymnema Sylvestre Extract is favored in the creation of weight management products, where it helps reduce sugar cravings and supports appetite control.
Gymnema Sylvestre Extract is utilized in the development of supplements for diabetes support, offering natural assistance in regulating blood sugar levels.

Gymnema Sylvestre Extract is widely used in the production of appetite suppressants, helping to reduce the desire for sugary foods and support weight management efforts.
Gymnema Sylvestre Extract is employed in the formulation of herbal teas, providing benefits for glucose control and appetite suppression.
Gymnema Sylvestre Extract is essential in the creation of holistic wellness products designed to maintain metabolic health and reduce sugar absorption.

Gymnema Sylvestre Extract is utilized in the production of anti-diabetic formulations, providing natural support for maintaining balanced blood glucose levels.
Gymnema Sylvestre Extract is a key ingredient in the development of detox teas, offering benefits for sugar control and overall metabolic balance.
Gymnema Sylvestre Extract is used in the creation of sugar-blocking supplements, helping to reduce sugar absorption in the body and support healthy metabolism.

Gymnema Sylvestre Extract is applied in the formulation of dietary capsules, offering benefits for reducing sugar cravings and promoting healthy glucose levels.
Gymnema Sylvestre Extract is employed in the production of functional foods, providing natural sugar-blocking benefits that support weight management.
Gymnema Sylvestre Extract is used in the development of blood sugar control supplements, offering holistic care for individuals managing diabetes or pre-diabetic conditions.

Gymnema Sylvestre Extract is widely utilized in the formulation of sugar-craving reduction products, providing natural support for appetite control and reducing sugar intake.
Gymnema Sylvestre Extract is a key component in the creation of metabolic balance supplements, offering benefits for maintaining healthy insulin sensitivity.
Gymnema Sylvestre Extract is used in the production of sugar-blocking beverages, helping to reduce sugar absorption and improve metabolic health.

Gymnema Sylvestre Extract is employed in the formulation of natural remedies for managing blood sugar, offering benefits for individuals with pre-diabetes or diabetes.
Gymnema Sylvestre Extract is applied in the development of nutritional supplements designed to support weight loss, appetite control, and blood sugar management.
Gymnema Sylvestre Extract is utilized in the creation of wellness beverages aimed at reducing sugar cravings and supporting healthy glucose metabolism.

Gymnema Sylvestre Extract is found in the formulation of functional foods and drinks, providing sugar-blocking benefits that support overall metabolic health.
Gymnema Sylvestre Extract is used in the production of supplements for holistic blood sugar control, offering support for glucose metabolism and sugar craving reduction.
Gymnema Sylvestre Extract is a key ingredient in weight loss teas, offering natural appetite-suppressing properties and supporting a balanced metabolism.

Gymnema Sylvestre Extract is widely used in the formulation of glucose-regulating supplements, helping to reduce sugar absorption and support healthy blood sugar levels.
Gymnema Sylvestre Extract is employed in the development of detox beverages, offering benefits for sugar control and reducing cravings.
Gymnema Sylvestre Extract is applied in the production of sugar-lowering capsules, offering natural support for individuals seeking to reduce their sugar intake and maintain balanced blood sugar levels.



DESCRIPTION


Gymnema Sylvestre Extract is a natural botanical ingredient derived from the leaves of the Gymnema sylvestre plant, known for its anti-diabetic, anti-inflammatory, and appetite-suppressing properties.
Gymnema Sylvestre Extract is widely recognized for its ability to reduce sugar absorption, promote healthy glucose levels, and support weight management, making it a valuable ingredient in dietary supplements and wellness formulations.

Gymnema Sylvestre Extract offers additional benefits such as improving insulin sensitivity, reducing sugar cravings, and supporting healthy metabolic function.
Gymnema Sylvestre Extract is often incorporated into formulations designed to provide comprehensive care for individuals managing diabetes, pre-diabetes, or weight management concerns.
Gymnema Sylvestre Extract is recognized for its ability to enhance the overall health of individuals by supporting balanced glucose levels and reducing the desire for sugary foods.

Gymnema Sylvestre Extract is commonly used in both traditional and innovative wellness formulations, providing a reliable solution for maintaining healthy blood sugar levels and appetite control.
Gymnema Sylvestre Extract is valued for its ability to support the body’s natural glucose regulation processes, making it a key ingredient in products that aim to improve metabolic health and reduce sugar absorption.
Gymnema Sylvestre Extract is a versatile ingredient that can be used in a variety of products, including supplements, capsules, teas, and functional foods.

Gymnema Sylvestre Extract is an ideal choice for products targeting weight management, sugar craving reduction, and blood sugar regulation, as it provides natural and effective support for these wellness concerns.
Gymnema Sylvestre Extract is known for its compatibility with other blood sugar-regulating and metabolic-enhancing ingredients, allowing it to be easily integrated into multi-functional formulations.
Gymnema Sylvestre Extract is often chosen for formulations that require a balance between sugar reduction, appetite suppression, and blood sugar control, ensuring comprehensive metabolic health benefits.

Gymnema Sylvestre Extract enhances the overall effectiveness of personal care and wellness products by providing natural support for appetite control, blood sugar management, and metabolic balance.
Gymnema Sylvestre Extract is a reliable ingredient for creating products that offer a pleasant user experience, with noticeable improvements in appetite, glucose levels, and cravings.
Gymnema Sylvestre Extract is an essential component in innovative wellness products that stand out in the market for their performance, safety, and ability to support metabolic health.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Gymnema Sylvestre Extract (Gymnema sylvestre Leaf Extract)
Molecular Structure:
Appearance: Yellow to brown powder
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low



FIRST AID


Inhalation:
If Gymnema Sylvestre Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Gymnema Sylvestre Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Gymnema Sylvestre Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Gymnema Sylvestre Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Gymnema Sylvestre Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.

GYNOSTEMMA P. (JIAOGULAN) EXTRACT

Gynostemma P. Extract, derived from the Gynostemma pentaphyllum plant, also known as Jiaogulan, is recognized for its adaptogenic, antioxidant, and anti-inflammatory properties.
Gynostemma P. (Jiaogulan) Extract is widely known for its ability to help balance the body's systems, support immune health, and reduce oxidative stress, making it a valuable ingredient in wellness formulations.
This versatile extract offers both therapeutic and wellness benefits, helping to maintain overall health, energy balance, and resilience to stress.

CAS Number: 223751-91-1
EC Number: Not available

Synonyms: Gynostemma Extract, Jiaogulan Extract, Gynostemma pentaphyllum Extract, Southern Ginseng Extract, Miracle Grass Extract, Gynostemma Herbal Extract, Jiaogulan Phytoextract, Gynostemma Bioactive Extract, Five-leaf Ginseng Extract, Gynostemma Pentaphyllum Active



APPLICATIONS


Gynostemma P. (Jiaogulan) Extract is extensively used in the formulation of adaptogenic supplements, where it helps the body adapt to stress and promotes mental and physical balance.
Gynostemma P. (Jiaogulan) Extract is favored in the creation of immune-boosting supplements, supporting overall immune health and enhancing the body's natural defenses.
Gynostemma P. (Jiaogulan) Extract is utilized in the development of anti-inflammatory products, offering natural relief from inflammation and supporting overall wellness.

Gynostemma P. (Jiaogulan) Extract is widely used in the production of antioxidant-rich supplements, helping to protect the body from oxidative stress and free radical damage.
Gynostemma P. (Jiaogulan) Extract is employed in the formulation of energy-boosting supplements, offering natural support for improved stamina and reduced fatigue.
Gynostemma P. (Jiaogulan) Extract is essential in the creation of detox teas, helping to cleanse the body of toxins and support liver function.

Gynostemma P. (Jiaogulan) Extract is utilized in the production of cardiovascular support products, helping to promote heart health and improve blood circulation.
Gynostemma P. (Jiaogulan) Extract is a key ingredient in the formulation of wellness beverages, offering adaptogenic benefits and supporting overall vitality.
Gynostemma P. (Jiaogulan) Extract is used in the creation of stress-relief supplements, promoting calmness and reducing the effects of stress on the body.

Gynostemma P. (Jiaogulan) Extract is applied in the formulation of anti-aging supplements, offering antioxidant and anti-inflammatory properties that support healthy aging.
Gynostemma P. (Jiaogulan) Extract is employed in the production of holistic health supplements, providing adaptogenic benefits that help the body cope with mental and physical stressors.
Gynostemma P. (Jiaogulan) Extract is used in the development of weight management supplements, offering benefits for regulating metabolism and supporting healthy weight loss.

Gynostemma P. (Jiaogulan) Extract is widely utilized in the formulation of herbal teas, where it provides adaptogenic and immune-boosting benefits.
Gynostemma P. (Jiaogulan) Extract is a key component in the creation of metabolic health supplements, helping to balance blood sugar levels and improve insulin sensitivity.
Gynostemma P. (Jiaogulan) Extract is used in the production of detoxifying beverages, offering antioxidant and liver-supportive benefits.

Gynostemma P. (Jiaogulan) Extract is employed in the formulation of energy drinks, providing natural stamina and endurance support without the need for stimulants.
Gynostemma P. (Jiaogulan) Extract is applied in the development of supplements designed to enhance endurance and resilience, supporting physical and mental performance.
Gynostemma P. (Jiaogulan) Extract is utilized in the creation of wellness capsules, providing holistic support for immune function, metabolic health, and stress relief.

Gynostemma P. (Jiaogulan) Extract is found in the formulation of immune-boosting teas, offering adaptogenic benefits and supporting overall vitality and well-being.
Gynostemma P. (Jiaogulan) Extract is used in the production of holistic wellness beverages, supporting healthy aging, cardiovascular health, and immune function.
Gynostemma P. (Jiaogulan) Extract is a key ingredient in stress-relief supplements, providing natural adaptogenic benefits that reduce the effects of stress on the body.



DESCRIPTION


Gynostemma P. Extract, derived from the Gynostemma pentaphyllum plant, also known as Jiaogulan, is recognized for its adaptogenic, antioxidant, and anti-inflammatory properties.
Gynostemma P. (Jiaogulan) Extract is widely known for its ability to help balance the body's systems, support immune health, and reduce oxidative stress, making it a valuable ingredient in wellness formulations.

Gynostemma P. (Jiaogulan) Extract offers additional benefits such as promoting cardiovascular health, supporting metabolic function, and enhancing the body's ability to cope with mental and physical stressors.
Gynostemma P. (Jiaogulan) Extract is often incorporated into formulations designed to promote longevity, vitality, and resilience against stress and fatigue.
Gynostemma P. (Jiaogulan) Extract is recognized for its ability to enhance the body's natural defense mechanisms, supporting immune function and protecting against oxidative damage.

Gynostemma P. (Jiaogulan) Extract is commonly used in both traditional and innovative wellness formulations, providing a reliable solution for maintaining balance, energy, and overall health.
Gynostemma P. (Jiaogulan) Extract is valued for its ability to support the body’s natural healing processes and its adaptogenic properties, making it a key ingredient in products that aim to enhance mental and physical performance.
Gynostemma P. (Jiaogulan) Extract is a versatile ingredient that can be used in a variety of products, including supplements, teas, capsules, and wellness beverages.

Gynostemma P. (Jiaogulan) Extract is an ideal choice for products targeting stress relief, immune support, and cardiovascular health, as it provides natural and effective care for these wellness concerns.
Gynostemma P. (Jiaogulan) Extract is known for its compatibility with other adaptogenic and antioxidant ingredients, allowing it to be easily integrated into multi-functional formulations.
Gynostemma P. (Jiaogulan) Extract is often chosen for formulations that require a balance between energy support, immune health, and stress reduction, ensuring comprehensive wellness benefits.

Gynostemma P. (Jiaogulan) Extract enhances the overall effectiveness of wellness products by providing natural support for stress management, immune function, and energy balance.
Gynostemma P. (Jiaogulan) Extract is a reliable ingredient for creating products that offer a pleasant user experience, with noticeable improvements in energy, vitality, and stress resilience.
Gynostemma P. (Jiaogulan) Extract is an essential component in innovative wellness products that stand out in the market for their performance, safety, and ability to support overall health and longevity.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Gynostemma Extract (Gynostemma pentaphyllum Extract)
Molecular Structure:
Appearance: Light yellow to brown powder or liquid
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If Gynostemma Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Gynostemma Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Gynostemma Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Gynostemma Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Gynostemma Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.


HALAMID
Halamid, commonly known as chloramine-T, exerts strong oxidizing action in both acidic and alkaline media and thus has been widely used for the oxidimetric determination of a large number of inorganic and organic substances.
Oxidation of some aldehydes by Halamid has been reported to occur quantitatively in an alkaline solution, giving the corresponding acid as the end product.
Both direct and indirect methods have been carried out to estimate aldehydes by Halamid.

CAS: 127-65-1
MF: C7H7ClNNaO2S
MW: 227.64
EINECS: 204-854-7

Halamid is also commonly used in radiolabeling bioactive molecules by halogenation.
Halamid is used to release radioactive elemental iodine by oxidation of its salts.
Unfortunately, Halamid is a strong oxidizing agent and can cause significant damage to peptides and proteins.
This may lower the yield of the iodination reaction and may produce undesirable side products.
An organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.
Halamid is the organic compound with the formula CH3C6H4SO2NClNa.
Both the anhydrous salt and its trihydrate are known.
Both are white powders. Halamid is used as a reagent in organic synthesis.
Halamid is commonly used as cyclizing agent in the synthesis of aziridine, oxadiazole, isoxazole and pyrazoles.
Halamid's inexpensive, has low toxicity and acts as a mild oxidizing agent.
In addition, Halamid also acts as a source of nitrogen anions and electrophilic cations.
Halamid may undergo degradation on long term exposure to atmosphere such that care must be taken during its storage.

Halamid is a disinfectant that is used to treat wastewater and as a preservative for water.
Halamid has been shown to be effective against bacteria, fungi, and viruses.
Halamid is an antimicrobial agent that reacts with the matrix in which it is applied to form chloramines-T (NHClO).
Halamid inhibits the activity of enzymes such as those involved in DNA synthesis and protein synthesis.
This reaction also generates an electric current due to the redox potentials of the reactants.
The presence of aziridines in Halamid leads to crosslinking between proteins, which enhances its effectiveness as a disinfectant.
Halamid has been shown to have no adverse effects on human erythrocytes or DNA when used at concentrations up to 100 µg/mL.
Halamid has been widely used in laboratories and veterinary facilities to control pathogens by surface disinfection and soaking equipment.
Halamid is a biocide which has been tested against a number of bacteria, virus, and parasites specific to aquaculture.
Halamid has many benefits such as being non-corrosive to equipment (once diluted), easy to use, biodegradable, long term storage stability and no risk of possible disease resistance.
Halamid is non-toxic and does not leave residues that can adversely affect animals after disinfection.

Halamid readily biodegradable disinfectant which is widely used as a germicide in sanitary practices, because of the following properties.
Active against bacteria (Gram positive and Gram negative), viruses (naked as well as enveloped) and fungi.
Stable and active at low as well as elevated temperatures.
Safe to handle, both powder and aqueous solution.
Safe to nature, readily biodegradable and none of the chlorine disadvantages.
Superior storage stability.
No risk of building up resistant microorganisms.

Halamid Chemical Properties
Melting point: 167-170 °C(lit.)
Density: 1.401[at 20℃]
Vapor pressure: 0Pa at 25℃
Storage temp.: Sealed in dry,2-8°C
Solubility H2O: >100 mg/mL
Pka 0.39[at 20 ℃]
Water Solubility: 150g/L at 25℃
Stability: Stable. Incompatible with strong oxidizing agents. May decompose violently if heated above 130 C. May decompose on exposure to air.
InChI InChI=1S/C7H7ClNO2S.Na/c1-6-2-4-7(5-3-6)12(10,11)9-8;/h2-5H,1H3;/q-1;+1
InChIKey: VDQQXEISLMTGAB-UHFFFAOYSA-N
SMILES: S(=O)(=O)(N(Cl)[Na])C1C=CC(C)=CC=1
LogP: -1.3 at 20℃
CAS DataBase Reference: 127-65-1(CAS DataBase Reference)
EPA Substance Registry System: Halamid (127-65-1)

Uses
Halamid is for external use only, it can exterminate bacteria, viruses, fungi, spore.
The action principle is that chlorine can sterilize slowly and lastingly, and also can dissolve necrotic tissue, chlorine come from hypochlorous acid which is produced Halamid solution.
Apply to disinfect drinking water container,food,all kind of tableware, fruits and vegetables,and cleaning wound, mucous membrane.
Sterilizer, antiseptic, disinfectant, and chemical reagent in the medical and pharmaceutical fields.

Tosylchloramide sodium salt (C7H7CINO2S), known commercially as Halamid, is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant.
Halamid is a white powder that gives unstable solutions with water.
Halamid is used for disinfection and as an algicide, bactericide, germicide, for parasite control, and for drinking water disinfection.
Halamid has been used in ornamental fish and aquaculture industries for many years, making it especially useful for disinfecting angling equipment before and after fishing.
Halamid is also used for disinfection in saunas, solariums, gyms, sport centres, kitchens, sanitary facilities, and air conditioning units.
Halamid is simple and safe to use, dissolves in water (warm) and immediately produces a ready-to-use, highly effective and long-lasting disinfectant solution that lasts up to eight weeks in special UV protected spray bottles.

Reagent in amidohydroxylation
The Sharpless oxyamination converts an alkene to a vicinal aminoalcohol.
A common source of the amido component of this reaction is Halamid.
Vicinal aminoalcohols are important products in organic synthesis and recurring pharmacophores in drug discovery.

Oxidant
Halamid is a strong oxidant.
Halamid oxidizes hydrogen sulfide to sulfur and mustard gas to yield a harmless crystalline sulfimide.
Halamid converts iodide to iodine monochloride (ICl).
ICl rapidly undergoes electrophilic substitution predominantly with activated aromatic rings, such as those of the amino acid tyrosine.
Thus, Halamid is used to incorporate iodine into peptides and proteins.
Halamid together with iodogen or lactoperoxidase is commonly used for labeling peptides and proteins with radioiodine isotopes.

Synthesis
Halamid is prepared in 75 – 95 % yield by passing chlorine into a sodium hydroxide solution of p-toluenesulfonamide.
Halamid is a strong electrolyte in acid solution and a good oxidizing agent in base.
Halamid is fairly soluble in water, and practically insoluble in benzene, chloroform, and ether.
Halamid reacts readily with mustard gas to yield a harmless crystalline sulfimide.
Halamid derivatives are being studied as protective agents against poison gas.

Synonyms
Chloramine-T
CHLORAMINE T
127-65-1
Chloralone
Chlorasan
Chlorozone
Acti-chlore
Tosylchloramide sodium
Chloraseptine
Chlorazan
Chlorazene
Chlorazone
Chlorosol
Chlorseptol
Heliogen
Mannolite
Tampules
Tochlorine
Tolamine
Sodium chloramine T
Monochloramine T
Multichlor
Aktivin
Sodium p-toluenesulfonchloramide
Chlorina Aktivin
Sodium tosylchloramide
Tosilcloramida sodica
Sodium chloro(tosyl)amide
Tosylchloramide sodique
(N-Chloro-p-toluenesulfonamido)sodium
Sodium p-toluenesulfonylchloramide
Tosylchloramidum natricum
Berkendyl
Clorina
Euclorina
N-Chloro-p-toluenesulfonamide sodium
Sodium N-chloro-p-toluenesulfonamide
Anexol
chloramine-T anhydrous
Cloramine T
Gyneclorina
Clorosan
Halamid
Mianine
Gansil
Chloramin Heyden
Kloramine-T
CHEBI:53767
Tosylchloramide sodium [INN]
Chloramin Dr. Fahlberg
328AS34YM6
N-Chlorotoluenesulfonamide sodium salt
N-Chloro-4-methylbenzylsulfonamide sodium salt
DTXSID6040321
sodium chloro(4-methylbenzenesulfonyl)azanide
[chloro(p-tolylsulfonyl)amino]sodium
NSC-36959
Aseptoclean
Desinfect
Tosylchloramid-natrium
Benzenesulfonamide, N-chloro-4-methyl-, sodium salt
149358-73-6
Tosylchloramide sodium (INN)
N-Chloro-p-toluenesulfonamide sodium salt
Caswell No. 170
Benzenesulfonamide, N-chloro-4-methyl-, sodium salt (1:1)
Chloramine-t [NF]
TOSYLCHLORAMIDE SODIUM (EP IMPURITY)
TOSYLCHLORAMIDE SODIUM [EP IMPURITY]
TOSYLCHLORAMIDE SODIUM (EP MONOGRAPH)
TOSYLCHLORAMIDE SODIUM [EP MONOGRAPH]
p-Toluenesulfonchloramide Sodium Salt
sodium chloro((4-methylphenyl)sulfonyl)azanide
sodium chloro[(4-methylphenyl)sulfonyl]azanide
HSDB 4303
SR-01000872612
EINECS 204-854-7
Tosilcloramida sodica [INN-Spanish]
N-Chloro-4-methylbenzenesulfonamide sodium salt
NSC 36959
Tosylchloramide sodique [INN-French]
(N-chloro-p-toluenesulfonamide)sodium
Tosylchloramidum natricum [INN-Latin]
AI3-18426C
EPA Pesticide Chemical Code 076502
UNII-328AS34YM6
Chloramin T
p-Toluenesulfonamide, N-chloro-, sodium salt
Tosyl chloramide sodium
Sodiumchloro(tosyl)amide
CHLORAMINE-T [MI]
Epitope ID:116223
CHLORAMINE T [INCI]
CHLORAMINE-T [HSDB]
SCHEMBL19335
CHEMBL1697734
DTXCID4020321
VDQQXEISLMTGAB-UHFFFAOYSA-N
HMS3264N19
AMY37206
BCP12015
HY-B0959
s6403
Sodium N-chloro-4-toluenesulfonamide
AKOS015890257
CCG-213937
CS-4435
TOSYLCHLORAMIDE SODIUM [WHO-DD]
USEPA/OPP Pesticide Code: 076502
Sodium N-chloro 4-methylbenzenesulfonamide
FT-0654742
sodium;chloro-(4-methylphenyl)sulfonylazanide
Chloramine-T 1000 microg/mL in Acetonitrile
EN300-75322
D02445
D88065
Q420695
J-008582
SR-01000872612-2
SR-01000872612-3
W-108379
Chloramine (T) N-Chloro-4-toluenesulfonamide,sodium salt
Z1172235461
HALAMID
Halamid is an effective powder desinfection for all livestock with proven efficacy against a long list of bacteria and viruses.
Halamid is active at low temperatures, easily biodegradable, does not contain aldehydes or phenols, and there is no risk of developing resistance, wherefore rotation with other disinfectants is not necessary.
Halamid has effective at low temperatures.
Halamid is easily biodegradable.


CAS Number: 127-65-1
EC Number: 204-854-7
Molecular Formula: C7H7ClNNaO2S
Chemical formula: C7H7ClNO2S•Na / C7H7ClNO2S•Na•(3H2O) (hydrate)


Halamid is a universal, effective, easily biodegradable disinfectant, maintaining exceptional durability under appropriate storage conditions.
Tests have shown the high stability of Halamid, both in powder and solution form, thanks to which the product remains ready to be used with full effectiveness whenever it is needed.


Halamid is an organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.
Halamid is an oxidizing biocide.
Halamid is not stable in the water dissolved form.


The shelf life of Halamid is two years from the date of production, provided that it is stored in a closed, original packaging in a dry and cool place, without exposure to direct sunlight and high temperature.
Halamid is active, on pre-cleaned surfaces, against bacteria, fungi and viruses (usual cases) at a dilution of 0.5% and a contact time of at least 30 minutes.


Halamid is commonly used as cyclizing agent in the synthesis of aziridine, oxadiazole, isoxazole and pyrazoles.
Halamid contains a chloro(p-tolylsulfonyl)azanide.
Halamid is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant.


Depending on the resistance of the germ to be destroyed, a concentration of 0.25 - 1% is required.
Halamid is a disinfectant powder for private and public use, for use in veterinary hygiene ( including the fight against avian influenza virus ), for disinfection of surfaces in contact with food - Category I, groups 2, 3, 4.


Halamid is a very effective, powdered preparation.
Halamid fights 94 types of bacteria, 49 types of viruses, 22 types of fungi, 6 types of algae, 4 types of yeast and 4 types of parasites.
Halamid is recognized against: mycobacteria (not effective against M. tuberculosis), Aspergillus, Infectious bronchitis, Gumboro, EBO, REO virus, Aujeszky.


Halamid is a stabilized form of sodium hypochlorite.
Halamid can store at low temperature, ventilated and dry; store separately from acids.
Halamid is a mild bleach as active as sodium hypochlorite but without side effects.



A concentration of 2% is recommended for use in foot baths.
Halamid is active even in the presence of organic waste - the remains of litter.
The Halamid solution does not cause corrosion and does not affect the condition of the technical equipment of breeding facilities.


Halamid is active at low temperatures, so there is no need to heat buildings before disinfection.
Halamid is 100% biodegradable.
Due to its specific mechanism, Halamid does not cause resistance in pathogens, does not contain aldehydes and phenols.


Halamid is a white powder that gives unstable solutions with water.
Halamid is the organic compound with the formula CH3C6H4SO2NClNa.
Halamid has a role as an antifouling biocide, a disinfectant and an allergen.


Halamid combines the essential properties of a good disinfectant (broad spectrum of action and absence of corrosion), with a limited environmental impact.
Halamid is used for agri-food industries, hospitals, clinics and medical residences, veterinarians, farmers and fish farms.
Many specialists consider Halamid a unique, highly effective and universal disinfectant.


Since its first commercialization in 1947, Halamid has made a significant contribution to hygiene.
Halamid is an extremely concentrated powder.
Halamid has broad spectrum of activity against viruses, bacteria and fungi.


Halamid's a inexpensive, low toxic and mild oxidizing agent, and it also acts as a source of nitrogen anions and electrophilic cations.
But it may undergo degradation on long term exposure to atmosphere, so care must be taken during the storage.
Halamid is a white powder that gives unstable solutions with water.


Halamid has no aldehydes or phenols.
Without the risk of creating resistance, Halamid can be used without the need to alternate with other disinfectants.
The excellent efficacy of Halamid against problematic bacteria and viruses in poultry farming is confirmed by various laboratory tests and field trials.


Halamid covers all possible areas you need to disinfect in your farm - animal houses, equipment, vehicles and footbath.
Farmers successfully apply it by spraying, nebulisation or (thermo)fogging. intensive farming, the high density of animals increases the risk of diseases.
Buildings, equipment and lorries, when not properly cleaned and disinfected are responsible for the transmission of pathogenic microorganisms.


Halamid is a highly effective disinfectant for surfaces that come into contact with food and drink and their raw materials.
Halamid is a disinfectant that derives its effectiveness from bound chlorine and oxygen.
Halamid is characterized by a high content of stable active substance.


Halamid, also known as Halamid, is a chlorinated and deprotonated sulfonamide used as a mild disinfectant.
N-chloro tosylamide sodium salt, sold as Halamid, is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant.
Halamid is a titrimetric reagent, and an oxidizing agent.



Halamid enters into a chemical reaction (actually a combustion reaction) with micro-organisms.
Resistance formation of Halamid is therefore not possible.
Halamid's strength lies in its broad spectrum of activity and its relative mildness towards the user, materials and the environment.


Halamid is supplied per bucket in powder form and including a measuring scoop, making it easy and accurate to dose.
The disinfectant, Halamid, dissolves easily in water (maximum concentration 10% at 15°C).
Due to its mild character, Halamid is not corrosive to metals and other materials.


Halamid and Halamid-d are the same substance, but with a different authorization text.
Halamid is an effective powder disinfectant.
Halamid's outstanding properties meet all the requirements a professional disinfectant must have whatever the application of use.


Halamid is stable and active at low as well as elevated temperatures. Halamid is safe to handle, both powder and aqueous solution.
Halamid is safe to nature, readily biodegradable and has none of the chlorine disadvantages.
Halamid has superior storage stability.


Halamid has no risk of building up resistant microorganisms.
Halamid is the world’s most well-known universal disinfectant, with an impressive track record.
Halamid is a universal, readily biodegradable disinfectant which is widely used as a germicide in sanitary practices.


Halamid is already effective at very low dosage (0.01%) against bacteria (Gram + and Gram -), viruses (naked as well as enveloped) and fungi.
Halamid can be used in a wide range of temperatures.
Since no microorganism is able to build resistance against Halamid it can be applied for an indefinite period of time.


Halamid is safe to handle in either powder form or when dissolved in water.
Halamid is safe to nature as it is readily biodegradable.
The shelf life of Halamid is 2 years.


Halamid is a universal disinfectant with a wide activity spectrum yet mild to steel and other materials.
Halamid hydrate is capable of oxidative cyclization to produce various heterocycles.
Additionally, Halamid is useful as a reactant for preparation of factor Xa inhibitors as novel anticoagulants.



USES and APPLICATIONS of HALAMID:
Effective against all major problematic microorganisms, Halamid is widely used as a professional disinfectant in veterinary hygiene, aquaculture, food processing, institutional and health care areas, cooling towers and many other applications.
A truly versatile product, Halamid is a universal disinfectant.


The excellent efficacy of Halamid against problematic bacteria and viruses in farm and veterinary disinfection is confirmed by numerous laboratory tests and field trials.
Halamid is a livestock disinfectant that can be used in all areas that possibly need disinfection - animal houses, equipment, vehicles and footbaths.


Halamid can also be used as a Nitrene source for aziridinations and aminohydroxylations.
Apply to disinfect drinking water containers, food, all kind of tableware, fruits and vegetables, and clean wound, and mucous membrane.
Halamid is a disinfectant for external use, which has a killing effect on bacteria, viruses, fungi and spores.


Farmers successfully apply this livestock disinfectant by spraying, nebulisation or (thermo) fogging.
Veterinary disinfection whether on-farm or in the clinic is done with Halamid.
In the dairy industry, Halamid is used to disinfect cow teats as well as milking equipment.


And in poultry farming, hatching eggs are disinfected with Halamid.
Halamid is used as a proven hard-surface disinfectant, for use on equipment and air conditioning systems in public areas, e.g. hospitals, medical centres, aged care facilities and swimming pools.


Halamid is capable of oxidative cyclization to produce various heterocycles.
Halamid Trihydrate, Reagent, ACS is also known as tosylchloramide.
Halamid is used for bleaching paper documents.


These are known to be high-risk areas for infection.
Disinfectants are widely used In hospitals.
Some bacteria can become resistant to commonly used ingredients, leading to strains of resistant bacteria, which is a major concern for hygiene and safety.


Halamid can be used all year round without risk, as it reacts via an irreversible oxidizing mechanism, leaving no chance for the microorganisms (bacteria) to adapt.
Halamid is not only a surface disinfectant.


Abroad, Halamid in tablet form is widely used for disinfection of drinking water during and after emergency situations such as natural disasters, wars and outbreaks of infectious diseases, but also under normal conditions in the drinking water supply of residential areas.
Halamid is used as a reagent in organic synthesis.
Halamid is used biocides safely.


Halamid can also be used to disinfect hands, helping to reduce skin contamination and preventing the spread of bacteria and viruses.
Halamid is also used in hydrotherapy where it reduces the bacterial load in water.
Halamid is a disinfectant for professional use with bactericidal, fungicidal and virucidal action.


Halamid is only permitted for disinfecting stables, and transport vehicles and it may also be used in foot baths.
Halamid can be successfully used to disinfect rooms, vehicles and disinfection mats.
Halamid works as long as it is present in the form of a solution, so avoid intensive heating of the object before applying Halamid.


The time needed for disinfection does not exceed 30 minutes of exposure.
Due to the fact that Halamid works in the form of a water solution, it can be used on wet surfaces immediately after washing, only slightly increase the concentration of the working solution.


The biocidal effect of Halamid consists in the contact of the disinfected surface with a water solution, therefore any equipment for applying the solution to the disinfected surfaces can be used.
Halamide is perfectly soluble in water in the range of 0.5 to 10%.


Solutions retain their strength unchanged for many months: lower pH increases its disinfectant activity, higher pH decreases Halamid.
As an Halamid quality reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use.


In working solutions, Halamid is not irritating, and thanks to its oxidizing effect, it eliminates unpleasant odors.
Halamid is used for biocides with caution.
Halamid is used does not corrode the materials (contrary to many other disinfectants based on chlorine, peroxide or peracetic acid)


Halamid can be used for footbath and disinfection of transport vehicles.
Halamid is used in the food industry and healthcare for disinfecting floors, walls, tools and other surfaces.
Halamid is a mild disinfectant with high stability for reliable disinfection results.


Halamid is used biocides safely.
Effective against all major problematic microorganisms, Halamid is widely used as a professional disinfectant in Veterinary hygiene, aquaculture, food processing, institutional and health care areas, cooling towers and many other applications.


Halamid is suitable for disinfection of drinking utensils, food, various utensils, fruits and vegetables, and washing wounds and mucous membranes.
Halamid combines with iodogen or lactoperoxidase and is commonly used for labeling peptides and proteins with radioiodine isotopes.


A truly versatile product, Halamid is the universal disinfectant.
Halamid is a universal, readily biodegradable disinfectant which is widely used as a germicide in sanitary practices, because of the following properties: Active against bacteria (Gram positive and Gram negative), viruses (naked as well as enveloped) and fungi.


Halamid can be used for the treatment against White Spot, Costia and bacterial Gill Disease, as well as the reduction of pathogenic bacterial levels.
Thus, Halamid is used to incorporate iodine into peptides and proteins.
Halamid is most commonly used as a disinfectant or as a biocide.


Halamid is a global disinfectant widely used by professionals due to its long lasting and proven efficacy.
Halamid has been widely used in laboratories and veterinary facilities to control pathogens by surface disinfection and soaking equipment.
Halamid is a biocide which has been tested against a number of bacteria, virus, and parasites specific to aquaculture.


Halamid is a white powder and can be a source of electrophilic chlorine in organic synthesis.
Spectrum Chemical manufactured Halamid meet the toughest regulatory standards for quality and purity.
Also an all purpose disinfectant for lab and household use, and a slimicide for cooling water systems.


Halamid has many benefits such as being non-corrosive to equipment (once diluted), easy to use, biodegradable, long term storage stability and no risk of possible disease resistance.
Halamid is non-toxic and does not leave residues that can adversely affect animals after disinfection.


Halamid is the Universal Disinfectant which is used in numerous branches of industry like:
Intensive farming, hospitals, slaughterhouses, meat-packers and butcheries, breweries and soft drink industry, dairy and margarine industry, sugar and potato industry, food industry including canning, ice-cream industry, aquaculture, veterinary practice, water disinfection, personal hygiene, swimming pools, drinking water disinfection, waste water treatment, disinfecting washing powders.


Halamid trihydrate is used as an intermediate in the manufacture of chemical substances such as pharmaceuticals.
Halamid's working principle is to dissolve the Chemicalbook solution to produce hypochlorous acid and release chlorine, which has a slow and long-lasting sterilization effect and can dissolve necrotic tissue.


Halamid has been approved for disinfection where an approved product is required to be used under the control legislation for the following specific disease(s) orders;
Poultry diseases including avian influenza, influenza of avian origin in mammals, Newcastle disease, paramyxovirus at a dilution rate of this preparation plus 150 parts of water;


Halamid is for external use only, it can exterminate bacteria, viruses, fungi, spores.
The action principle is that chlorine can sterilize slowly and lastingly, and also can dissolve necrotic tissue, chlorine comes from hypochlorous acid which is produced by Halamid solution.


This disinfectant product has also been approved at a dilution of 1 part of this preparation plus 300 parts water for disinfection where General orders require the use of an approved disinfectant, but this approval does not apply to disinfection required under the specific control legislation relating to Swine Vesicular disease or Tuberculosis disease.


Hypochlorite released from Halamid acts as an effective oxidizing agent for iodide to form iodine monochloride (ICl).
In the pharmaceutical industry, Halamid is used to prepare disinfectants, determination and indicator of sulfa drugs.


Halamid can be used as a disinfectant to control bacteria, molds, yeasts and viruses.
Halamid together with iodogen or lactoperoxidase is commonly used for labeling peptides and proteins with radioiodine isotopes.


Halamid is very effective against pathogenic bacteria, viruses and prevents resistance of microorganisms.
Halamid virtually has no taste when added to the drinking water and is mild for water-pipes and water-tanks.


Halamid is used as a powder based treatment against Gill Flukes, Body Flukes, White Spot, Costia and Bacterial Gill Disease, as well as the reduction of pathogenic bacterial levels.


-Many branches of industry make use of Halamid like:
• Aquaculture
• Intensive farming
• Health care and public areas
• Food industry
• Slaughterhouses and meat-packers
• Breweries and soft drink industry
• Dairy and margarine industry
• Sugar and potato industry
• Industrial and institutional cleaning
• Veterinary industry


-Uses of Halamid:
Reagent in amidohydroxylation
The Sharpless oxyamination converts an alkene to a vicinal aminoalcohol.


-Halamid in poultry farming:
*Disinfection of fertile eggs
*Powder desinfection for stables, equipment, vehicles, and footbath
*Removes biofilm
*Economical in use
*Does not corrode materials


-Halamid can be used yet is not limited to applications like:
• Washing powder disinfectant
• (Drinking) water disinfection
• Deodorisation of gas and wastewater
• Equipment disinfection


-Use as a biocide
Halamid is used for disinfection and as an algicide, bactericide, germicide, for parasite control, and for drinking water disinfection.

The molecular structure of toluenesulfonylamide is similar to para-aminobenzoic acid, an intermediate in bacterial metabolism, which is disrupted by this sulfonamide (in the same way as by a sulfa drug).

Therefore, Halamid is capable of inhibiting with bacterial growth with two mechanisms, with the phenylsulfonamide moiety and the electrophilic chlorine.

A common source of the amido component of this reaction is Halamid.
Vicinal aminoalcohols are important products in organic synthesis and recurring pharmacophores in drug discovery.



HALAMID IS A UNIQUE PRODUCT:
• Versatile with a large activity spectrum
• Non corrosive in solutions for materials
• Stable
• Easy to handle
• No risk of building up resistant microorganisms
​• Registered and approved



BENEFITS OF HALAMID:
*arge activity spectrum
*Non-corrosive in the shown concentrations
*Non-corrosive in solution for materials
*Easy to use and versatile
*Stable
*Readily biodegradable
*No risk of building up resistant microorganisms
*Halamid is a strong concentrated powder disinfectant where the solutions are non-corrosive (as opposed to most other chlorine-, peroxide- or peracetic acid-based disinfectants).



REACTIONS OF HALAMID:
Halamid contains active (electrophilic) chlorine. Its reactivity is similar to that of sodium hypochlorite.
Aqueous solutions of Halamid are slightly basic (pH typically 8.5).
The pKa of the closely related N-chlorophenylsulfonamide C6H5SO2NClH is 9.5.

Halamid is prepared by oxidation of toluenesulfonamide with sodium hypochlorite, with the latter being produced in situ from sodium hydroxide and chlorine (Cl2).
Halamid is a strong oxidant.
Halamid oxidizes hydrogen sulfide to sulfur and mustard gas to yield a harmless crystalline sulfimide.

Halamid converts iodide to iodine monochloride (ICl).
ICl rapidly undergoes electrophilic substitution predominantly with activated aromatic rings, such as those of the amino acid tyrosine.



MODE OF ACTION OF HALAMID:
Halamid works via an oxidizing mechanism.
If dissolved in water Halamid ionises.
In this way chlorine is slowly released which will destruct cell walls of microbes.
There is no chance of creating resistance or adaptation.
The high stability of the ion gives Halamid a kind of "reservoir capacity", so its activity is not spent at once but remains present over a longer period.



FEATURES AND BENEFITS OF HALAMID:
Halamid has been shown to be effective against:
– 94 bacteria
– 49 viruses
– 22 mushrooms
– 6 seaweed
– 4 yeasts
– 4 parasites



CHEMISTRY OF HALAMID:
As a N-chloro compound, Halamid contains active (electrophilic) chlorine and can be compared to the O-chlorinated sodium hypochlorite.
Halamid is nearly neutral (pH typically 8.5).
In water, Halamid breaks down to the disinfectant hypochlorite.
Halamid can be used as a source of electrophilic chlorine in organic synthesis.
The sulfur adjacent to the nitrogen can stabilize a nitrogen anion (R2N–), so that the N-chloro sulfonyamide moiety can be deprotonated at nitrogen even with only sodium hydroxide.



100% EFFECTIVENESS IN COMBATING, AMONG OTHERS:
*Bacteria: Enterobacteriaceae, E. coli, Listeria, Pseudomonas Sp., Salmonella Sp.
*Fungi : Staphylococcus aureus, Streptococcus faecalis
*Viruses: Avian Influenza Virus, Avian Reoviruses, CELO Virus, Gumboro Disease, Infectious Bronchitis Virus.



SOME OF THE REASONS WHY HALAMID IS A UNIQUE PROFESSIONAL DISINFECTANT:
*Large activity spectrum
*Non corrosive in solution for materials
*Easy to use and versatile
*Stable
*Readily biodegradable
*No risk of building up resistant microorganisms



PHYSICAL and CHEMICAL PROPERTIES of HALAMID:
Molecular Weight: 227.64 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 226.9783716 g/mol
Monoisotopic Mass: 226.9783716 g/mol
Topological Polar Surface Area: 43.5Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 231
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Chemical formula: C7H7ClNO2S·Na
C7H7ClNO2S·Na·(3H2O) (hydrate)
Molar mass: 227.64 g/mol
281.69 g/mol (trihydrate)
Appearance: White powder
Density: 1.4 g/cm3
Melting point Releases chlorine at 130 °C (266 °F; 403 K)
Solid melts at 167–169 °C
Solubility in water >100 mg/mL (hydrate)
Molecular Weight: 227.64
Appearance: Solid
Formula: C7H7ClNNaO2S
CAS No.: 127-65-1

SMILES: O=S(C1=CC=C(C)C=C1)(N([Na])Cl)=O
Shipping: Room temperature in continental US; may vary elsewhere.
Storage: 4°C, sealed storage, away from moisture
Appearance: White Powder
Purity: ≥99%
Active Chlorine: ≥24.5%
PH: 8.0-11.0
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available

Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available

Water Solubility: 1.52 mg/mL
logP: -1
logP: 1.85
logS: -2.2
pKa (Strongest Acidic): 4.89
Physiological Charge: -1
Hydrogen Acceptor Count: 3
Hydrogen Donor Count: 0
Polar Surface Area: 43.37 Å2
Rotatable Bond Count: 1
Refractivity: 47.79 m3·mol-1
Polarizability: 18.65 Å3
Number of Rings: 1
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: No
MDDR-like Rule: No



FIRST AID MEASURES of HALAMID:
-Description of first-aid measures:
If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HALAMID:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



FIRE FIGHTING MEASURES of HALAMID:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of HALAMID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Choose body protection in relation to its type
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HALAMID:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of HALAMID:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Chloramine-T
CHLORAMINE T
127-65-1
Chloralone
Chlorasan
Chlorozone
Tosylchloramide sodium
Acti-chlore
Chloraseptine
Chlorazone
Chlorseptol
Multichlor
Tochlorine
Aktivin
Chlorazan
Chlorosol
Heliogen
Mannolite
Tampules
Tolamine
Sodium chloramine T
Chlorina Aktivin
Monochloramine T
Sodium tosylchloramide
Sodium p-toluenesulfonchloramide
Chlorazene
Tosilcloramida sodica
Sodium chloro(tosyl)amide
Tosylchloramide sodique
Tosylchloramidum natricum
Berkendyl
Clorina
Euclorina
Anexol
(N-Chloro-p-toluenesulfonamido)sodium
Sodium p-toluenesulfonylchloramide
Cloramine T
N-Chloro-p-toluenesulfonamide sodium
Sodium N-chloro-p-toluenesulfonamide
Gyneclorina
Clorosan
Halamid
Mianine
Gansil
Chloramin Heyden
Kloramine-T
Tosylchloramide sodium [INN]
CHEBI:53767
N-Chlorotoluenesulfonamide sodium salt
N-Chloro-4-methylbenzylsulfonamide sodium salt
sodium chloro(4-methylbenzenesulfonyl)azanide
328AS34YM6
[chloro(p-tolylsulfonyl)amino]sodium
Aseptoclean
Desinfect
Tosylchloramid-natrium
chloro-(4-methylphenyl)sulfonylazanide
149358-73-6
Tosylchloramide sodium (INN)
chloramine-T anhydrous
Caswell No. 170
Benzenesulfonamide
N-chloro-4-methyl-, sodium salt (1:1)
Chloramine-t [NF]
NSC-36959
p-Toluenesulfonchloramide Sodium Salt
HSDB 4303
SR-01000872612
N-Chloro-p-toluenesulfonamide sodium salt
EINECS 204-854-7
N-Chloro-4-methylbenzenesulfonamide sodium salt
NSC 36959
AI3-18426C
EPA Pesticide Chemical Code 076502
UNII-328AS34YM6
Chloramin T
p-Toluenesulfonamide, N-chloro-, sodium salt
Sodiumchloro(tosyl)amide
CHLORAMINE-T [MI]
Epitope ID:116223
CHLORAMINE T [INCI]
CHLORAMINE-T [HSDB]
SCHEMBL19335
CHEMBL1697734
DTXSID6040321
HMS3264N19
AMY37206
BCP12015
HY-B0959
s6403
AKOS015890257
CCG-213937
CS-4435
TOSYLCHLORAMIDE SODIUM [WHO-DD]
TOSYLCHLORAMIDE SODIUM [EP IMPURITY]
FT-0654742
TOSYLCHLORAMIDE SODIUM [EP MONOGRAPH]
Chloramine-T 1000 microg/mL in Acetonitrile
EN300-75322
sodium chloro[(4-methylphenyl)sulfonyl]azanide
D02445
D88065
Q420695
J-008582
SR-01000872612-2
SR-01000872612-3
W-108379
Chloramine (T) N-Chloro-4-toluenesulfonamide,sodium salt
Z1172235461



HALAMID(CHLORAMINE T)
Tosylchloramide sodium; Tosilcloramida sodica; Aktiven; Chloraseptine; Tochlorine; tolamine; Chlorazene; Chlorazone; Clorina; Halamid; Mianine; (N-Chloro-p-toluenesulfonamido) sodium; Sodium p-Toluenesulfonchloramide; p-Toluenesulfonchloramide Sodium Salt; N-Chloro-4-methylbenzenesulfonamide sodium salt; Tosylchloramidnatrium; Tosylchloramide sodique; N-Chloro-p-toluenesulfonamide, sodium salt; Sodium p-toluenesulfonchloramine; Sodium N-chloro-para-toluenesulfonamidate CAS NO:127-65-1 (Anhydrous) CAS NO: 7080-50-4 (Trihydrate)
HALOGEN FREE FLAME RETARDANT
Halogen Free Flame Retardant are chemical compounds used in materials such as plastics to increase their fire resistance.
Unlike traditional flame retardants, Halogen Free Flame Retardant's do not contain halogens such as chlorine or bromine, making them more environmentally friendly and less harmful to health.
These special additives react during a fire by absorbing heat and slowing down or suppressing the spread of flames.

CAS: 68333-79-9
MF: H12N3O4P
MW: 149.086741
EINECS: 269-789-9

Synonyms
polyphosphoric acids ammonium salts;APP;APP-0;XAP-01;APP-3;APP-1;ammonium polyphosphate flame retardant;Ammonium polyphosphate

Halogen Free Flame Retardant is a crystalline compound that contains phosphorus pentoxide and diammonium.
Halogen Free Flame Retardant is used for wastewater treatment, as an additive to plastics, and in the production of paper.
Halogen Free Flame Retardant can be synthesized from sodium citrate and crystalline cellulose.
The synthesis process involves heating the mixture at temperatures between 300°C and 400°C.
This process will produce a solid product with the desired reactants in the correct stoichiometric ratio.
Halogen Free Flame Retardant has been found to have synergistic effects when combined with other chemicals, such as enzymes or water-soluble phosphates.
Studies have shown that Halogen Free Flame Retardant improves the ability of enzymes to break down organic matter in biological systems; this may be due to its high water permeability properties.

Halogen Free Flame Retardant's are crucial for manufacturing safe and fire-resistant products in various industries, including construction, electronics, and transportation.
Their use enables the meeting of stringent safety standards without burdening the environment.
The introduction of halogen-free flame retardants is driven by concerns about the environmental and health impacts of halogenated compounds, which are known to produce harmful gases when burned and persist in ecosystems and organisms.
The use of Halogen Free Flame Retardant represents a sustainable and safer approach to reduce the flammability of materials.
In a world where safety and environmental protection are increasingly important, halogen-free flame retardants offer a fascinating perspective on the future of fire protection and materials science.

Halogen Free Flame Retardant have recently played a crucial role in fire protection and significantly influenced the development of polymer formulations and materials science.
The use of flame retardants is essential to reduce the fire hazard of materials and ensure product safety.
However, traditional halogenated flame retardants have disadvantages regarding their environmental compatibility and potential health risks.
In Halogen Free Flame Retardant, halogen-free alternatives are gaining prominence, offering effective fire suppression without environmental burden.

Halogen Free Flame Retardant is an organic salt of polyphosphoric acid and ammonia.
As a chemical, Halogen Free Flame Retardant is non-toxic, environmentally friendly and halogen-free.
Halogen Free Flame Retardant is most commonly used as a flame retardant, selection of the specific grade of ammonium polyphosphate can be determined by the solubility, Phosphorus content, chain length and polymerization degree.
The chain length (n) of this polymeric compound can be linear or branched.
Depending on the polymerization degree, there are two main families of ammonium polyphosphate: Crystal phase I APP (or APP I), and Crystal phase II APP (or APP II).
APP phase I has a short and linear chain (n < 100), Halogen Free Flame Retardant is more water sensitive (hydrolysis) and less thermally stable; actually it begins to decompose at temperatures above 150 °C.
The second family of Halogen Free Flame Retardant is the APP Phase II; which has an high polymerization degree, with n>1000, its structure is cross linked (branched), and it is an high-quality non-halogenated flame retardant.
APP phase II, Halogen Free Flame Retardant, has an higher thermal stability (the decomposition starts at approximately 300°C) and lower water solubility than APP I.

Halogen Free Flame Retardant Chemical Properties
Density: 1.74[at 20℃]
Vapor pressure: 0.076Pa at 20℃
Storage temp.: −20°C
Solubility: Aqueous Acid (Slightly)
Form: Solid
Color: White to Off-White
InChI: InChI=1S/3H3N.H3O4P/c;;;1-5(2,3)4/h3*1H3;(H3,1,2,3,4)
InChIKey: ZRIUUUJAJJNDSS-UHFFFAOYSA-N
LogP: -2.148 (est)
CAS DataBase Reference: 68333-79-9
EPA Substance Registry System: Halogen Free Flame Retardant (68333-79-9)

Halogen Free Flame Retardant is liquid fertilizers with compositions up to 11-37-0, manufactured by the reaction of anhydrous ammonia with superphosphoric acid.
Halogen Free Flame Retardant is made by the concentration of regular wet-process acid up to P2O5 concentrations of 78%.
Granular polyphosphates suitable for bulk blending are made by reacting ammonia with regular wet process acid of 52% P2O5 content and using the heat of reaction to drive off water to produce a phosphate melt of 10-43-0, with about 40% of the phosphorus in the polyphosphate form.
Hardal Ekstrakt
Brassica Nigra Seed Extract ; mustard seed extract cas no:90064-15-6
Haşhaş Ekstrakt
Papaver Somniferum Seed Extract ;extract of the seeds of the opium poppy, papaver somniferum l., papaveraceae; poppy seed extract cas no:84650-40-8
Havlıcan Ekstrakt
Alpinia Officinarum Leaf Extract; galangal leaf extract; chinese ginger leaf extract; languas officinarum leaf extract cas no:90320-42-6
HAVUÇ AROMASI
carrot flavor; carrot vegetable powder
Havuç Ekstraktı
Daucus Carota Sativa Root Extract ;carrot root extract; lipoactive carrot ;phytoconcentrole carrot cas no:84929-61-3
Havyar Ekstraktı
Caviar Extract ; extract of the eggs of sturgeon, of the family acipenseridae cas no: N/A
HAWTHORN BERRY EXTRACT

Hawthorn Berry Extract is a natural botanical ingredient derived from the berries of the Crataegus species, known for its cardioprotective, antioxidant, and anti-inflammatory properties.
Hawthorn Berry Extract is widely recognized for its ability to support heart health, improve blood circulation, and protect against oxidative stress, making it a valuable ingredient in wellness formulations.
This versatile extract offers both therapeutic and wellness benefits, helping to maintain cardiovascular health, reduce inflammation, and support overall well-being.

CAS Number: 84603-61-2
EC Number: 283-289-8

Synonyms: Hawthorn Berry Extract, Crataegus Extract, Crataegus Monogyna Extract, Crataegus Oxyacantha Extract, Hawthorn Fruit Extract, Mayblossom Extract, Hawthorn Bioactive Extract, Hawthorn Antioxidant Extract, Hawthorn Phytocomplex, Hawthorn Herbal Extract, Hawthorn Cardiovascular Active, Crataegus spp. Extract



APPLICATIONS


Hawthorn Berry Extract is extensively used in the formulation of cardiovascular supplements, supporting heart health and improving blood circulation.
Hawthorn Berry Extract is favored in the creation of blood pressure support products, where it helps to regulate blood pressure levels and improve vascular health.
Hawthorn Berry Extract is utilized in the development of antioxidant-rich supplements, offering protection against oxidative stress and free radical damage.

Hawthorn Berry Extract is widely used in the production of anti-inflammatory supplements, helping to reduce inflammation and support overall cardiovascular health.
Hawthorn Berry Extract is employed in the formulation of heart health teas, providing benefits for improving circulation and maintaining cardiovascular wellness.
Hawthorn Berry Extract is essential in the creation of holistic wellness products designed to support heart health and protect against oxidative stress.

Hawthorn Berry Extract is utilized in the production of cholesterol-lowering supplements, where it helps to reduce bad cholesterol (LDL) and improve overall lipid profiles.
Hawthorn Berry Extract is a key ingredient in the formulation of detox teas, offering cardiovascular benefits while supporting liver health and detoxification.
Hawthorn Berry Extract is used in the creation of blood pressure-regulating supplements, helping to maintain healthy blood pressure levels and promote heart health.

Hawthorn Berry Extract is applied in the formulation of energy-boosting supplements, providing cardiovascular support while improving stamina and reducing fatigue.
Hawthorn Berry Extract is employed in the production of heart-friendly functional foods, offering natural support for cardiovascular health and circulation.
Hawthorn Berry Extract is used in the development of anti-oxidative capsules, providing protection against oxidative stress and promoting cardiovascular wellness.

Hawthorn Berry Extract is widely utilized in the formulation of natural remedies for heart health, providing benefits for improving circulation and reducing oxidative damage.
Hawthorn Berry Extract is a key component in the creation of cholesterol-lowering teas, helping to improve lipid profiles and promote overall cardiovascular health.
Hawthorn Berry Extract is used in the production of blood pressure-reducing beverages, offering natural support for healthy blood pressure and heart function.

Hawthorn Berry Extract is employed in the formulation of anti-aging supplements, offering cardiovascular and antioxidant benefits that support healthy aging.
Hawthorn Berry Extract is applied in the development of stress-relief supplements, providing cardiovascular protection while reducing the effects of stress on the body.
Hawthorn Berry Extract is utilized in the creation of wellness capsules, providing natural support for heart health, circulation, and antioxidant protection.

Hawthorn Berry Extract is found in the formulation of anti-inflammatory teas, providing cardiovascular benefits and protection against oxidative damage.
Hawthorn Berry Extract is used in the production of heart-healthy beverages, offering natural support for circulation and overall cardiovascular wellness.
Hawthorn Berry Extract is a key ingredient in detoxifying supplements, helping to cleanse the body while supporting heart health and antioxidant protection.



DESCRIPTION


Hawthorn Berry Extract is a natural botanical ingredient derived from the berries of the Crataegus species, known for its cardioprotective, antioxidant, and anti-inflammatory properties.
Hawthorn Berry Extract is widely recognized for its ability to support heart health, improve blood circulation, and protect against oxidative stress, making it a valuable ingredient in wellness formulations.

Hawthorn Berry Extract offers additional benefits such as improving lipid profiles, reducing cholesterol levels, and supporting healthy blood pressure.
Hawthorn Berry Extract is often incorporated into formulations designed to provide comprehensive cardiovascular support, helping to promote heart health and improve overall circulation.
Hawthorn Berry Extract is recognized for its ability to enhance the overall health of individuals by supporting healthy aging, reducing inflammation, and protecting against oxidative damage.

Hawthorn Berry Extract is commonly used in both traditional and innovative wellness formulations, providing a reliable solution for maintaining cardiovascular health and reducing oxidative stress.
Hawthorn Berry Extract is valued for its ability to support the body’s natural cardiovascular and circulatory functions, making it a key ingredient in products that aim to protect the heart and improve circulation.
Hawthorn Berry Extract is a versatile ingredient that can be used in a variety of products, including supplements, teas, capsules, and functional foods.

Hawthorn Berry Extract is an ideal choice for products targeting heart health, cholesterol reduction, and blood pressure regulation, as it provides natural and effective support for these cardiovascular concerns.
Hawthorn Berry Extract is known for its compatibility with other heart-healthy ingredients, allowing it to be easily integrated into multi-functional formulations.
Hawthorn Berry Extract is often chosen for formulations that require a balance between cardiovascular support, antioxidant protection, and cholesterol management, ensuring comprehensive heart health benefits.

Hawthorn Berry Extract enhances the overall effectiveness of wellness products by providing natural support for heart health, circulation, and antioxidant protection.
Hawthorn Berry Extract is a reliable ingredient for creating products that offer a pleasant user experience, with noticeable improvements in circulation, heart function, and cholesterol levels.
Hawthorn Berry Extract is an essential component in innovative wellness products that stand out in the market for their performance, safety, and ability to support cardiovascular health and longevity.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Hawthorn Berry Extract (Crataegus spp. Berry Extract)
Molecular Structure:
Appearance: Red-brown powder or liquid extract
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If Hawthorn Berry Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Hawthorn Berry Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Hawthorn Berry Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Hawthorn Berry Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Hawthorn Berry Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.
HAWTHORN LEAF EXTRACT

Hawthorn Leaf Extract is a natural botanical ingredient derived from the leaves of the Crataegus species, known for its cardioprotective, antioxidant, and anti-inflammatory properties.
Hawthorn Leaf Extract is widely recognized for its ability to support cardiovascular health, improve blood circulation, and protect against oxidative stress, making it a valuable ingredient in wellness formulations.
This versatile extract offers both therapeutic and wellness benefits, helping to maintain heart health, reduce inflammation, and promote overall well-being.

CAS Number: 90045-49-7
EC Number: 289-905-9

Synonyms: Hawthorn Leaf Extract, Crataegus Leaf Extract, Crataegus Monogyna Leaf Extract, Crataegus Oxyacantha Leaf Extract, Mayblossom Leaf Extract, Hawthorn Bioactive Extract, Hawthorn Cardiovascular Extract, Crataegus Leaf Phytocomplex, Hawthorn Leaf Herbal Extract



APPLICATIONS


Hawthorn Leaf Extract is extensively used in cardiovascular supplements, providing natural support for heart health and improving blood circulation.
Hawthorn Leaf Extract is favored in the formulation of blood pressure support supplements, helping regulate blood pressure levels and improve vascular health.
Hawthorn Leaf Extract is utilized in the development of antioxidant-rich supplements, offering protection against oxidative stress and free radical damage.

Hawthorn Leaf Extract is widely used in anti-inflammatory supplements, helping to reduce inflammation and support overall cardiovascular health.
Hawthorn Leaf Extract is employed in heart health teas, providing benefits for promoting circulation and cardiovascular wellness.
Hawthorn Leaf Extract is essential in creating holistic wellness products designed to support heart health and protect against oxidative stress.

Hawthorn Leaf Extract is utilized in the production of cholesterol-lowering supplements, helping reduce bad cholesterol (LDL) and improve lipid profiles.
Hawthorn Leaf Extract is a key ingredient in detox teas, offering cardiovascular benefits while supporting liver health and detoxification.
Hawthorn Leaf Extract is used in blood pressure-regulating supplements, promoting heart health and helping maintain healthy blood pressure levels.

Hawthorn Leaf Extract is applied in energy-boosting supplements, providing cardiovascular support while improving stamina and reducing fatigue.
Hawthorn Leaf Extract is employed in the creation of heart-friendly functional foods, offering natural support for cardiovascular health and circulation.
Hawthorn Leaf Extract is used in the development of antioxidant capsules, offering protection against oxidative stress and promoting cardiovascular wellness.

Hawthorn Leaf Extract is widely utilized in natural remedies for heart health, providing benefits for improving circulation and reducing oxidative damage.
Hawthorn Leaf Extract is a key component in cholesterol-lowering teas, promoting heart health and improving lipid profiles.
Hawthorn Leaf Extract is used in blood pressure-reducing beverages, supporting healthy blood pressure and heart function.

Hawthorn Leaf Extract is employed in anti-aging supplements, providing cardiovascular and antioxidant benefits that support healthy aging.
Hawthorn Leaf Extract is applied in stress-relief supplements, providing cardiovascular protection while reducing the effects of stress on the body.
Hawthorn Leaf Extract is used in wellness capsules, providing natural support for heart health, circulation, and antioxidant protection.

Hawthorn Leaf Extract is found in anti-inflammatory teas, providing cardiovascular benefits and protection against oxidative damage.
Hawthorn Leaf Extract is used in heart-healthy beverages, offering natural support for circulation and cardiovascular wellness.
Hawthorn Leaf Extract is a key ingredient in detoxifying supplements, helping cleanse the body while supporting heart health and antioxidant protection.



DESCRIPTION


Hawthorn Leaf Extract is a natural botanical ingredient derived from the leaves of the Crataegus species, known for its cardioprotective, antioxidant, and anti-inflammatory properties.
Hawthorn Leaf Extract is widely recognized for its ability to support heart health, improve blood circulation, and protect against oxidative stress, making it a valuable ingredient in wellness formulations.

Hawthorn Leaf Extract offers additional benefits such as improving lipid profiles, supporting healthy blood pressure, and reducing cholesterol levels.
Hawthorn Leaf Extract is often incorporated into formulations designed to promote comprehensive cardiovascular support, helping improve circulation and heart health.
Hawthorn Leaf Extract is recognized for its ability to enhance overall cardiovascular health, providing protection against oxidative stress and inflammation.

Hawthorn Leaf Extract is commonly used in both traditional and innovative wellness formulations, providing a reliable solution for maintaining cardiovascular health and reducing oxidative stress.
Hawthorn Leaf Extract is valued for its ability to support the body’s cardiovascular system, making it a key ingredient in products aimed at protecting the heart and improving circulation.
Hawthorn Leaf Extract is a versatile ingredient that can be used in a variety of products, including supplements, teas, capsules, and functional foods.

Hawthorn Leaf Extract is an ideal choice for products targeting cardiovascular health, cholesterol reduction, and blood pressure regulation, providing natural and effective support for these concerns.
Hawthorn Leaf Extract is known for its compatibility with other heart-healthy ingredients, making it easy to integrate into multi-functional formulations.
Hawthorn Leaf Extract is often chosen for formulations requiring a balance between cardiovascular support, antioxidant protection, and cholesterol management, ensuring comprehensive heart health benefits.

Hawthorn Leaf Extract enhances the overall effectiveness of wellness products by providing natural support for cardiovascular health, circulation, and antioxidant protection.
Hawthorn Leaf Extract is a reliable ingredient for creating products that offer a pleasant user experience, with noticeable improvements in circulation, heart function, and blood pressure.
Hawthorn Leaf Extract is an essential component in innovative wellness products known for their performance, safety, and ability to support heart health and longevity.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Hawthorn Leaf Extract (Crataegus spp. Leaf Extract)
Molecular Structure:
Appearance: Green to brown powder or liquid extract
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If Hawthorn Leaf Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Hawthorn Leaf Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Hawthorn Leaf Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Hawthorn Leaf Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Hawthorn Leaf Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.
Hayıt Ekstrakt
Vitex Agnus Castus Extract ;vitex agnus-castus leaf cell extract; abrahams balm leaf cell extract; chaste tree leaf cell extract; chasteberry leaf cell extract; monks pepper leaf cell extract cas no:91722-47-3
HDO (1,6-HEXANEDIOL)
HDO (1,6-Hexanediol) as a building block for the production of polyester and polyurethane resins.
Good balance between hardness and flexibility, adhesion, weatherability or hydrolysis resistance.
HDO (1,6-Hexanediol) is also applied in the manufacturing process of radiation-curable coatings, polycarbonate diols and as a reactive thinner for the formulation of epoxy systems which are used for the efficient production of rotor blades for modern wind turbines.

CAS: 629-11-8
MF: C6H14O2
MW: 118.17
EINECS: 211-074-0

HDO (1,6-Hexanediol) is a waxy hygroscopic solid compound that is white in colour.
HDO (1,6-Hexanediol) is a linear diol that contains two primary hydroxyl groups that are located at the terminal.
HDO (1,6-Hexanediol)’s linear hydrocarbon chain enables the compound to have enhanced hardness and flexibility of polyesters.
Moreover, this property is utilized in the extending chains in polyurethanes.
HDO (1,6-Hexanediol) is straight-chained, bifunctional primary alcohol.
HDO (1,6-Hexanediol) is a white waxy solid at room temperature and has a melting point of 42°C.
HDO (1,6-Hexanediol) dissolves in a wide variety of organic solvents and water.
HDO (1,6-Hexanediol) is an organic compound with the formula HOCH2(CH2)4CH2OH.

HDO (1,6-Hexanediol) is a building block for saturated polyesters and polyurethanes acrylic esters of 1,6-Hexanediol are used as reactive diluent for UV-coatings.
HDO (1,6-Hexanediol) is used in polyesters for solvent-borne paints, in stoving enamels for automotive coatings, for can-& coil-coating and for general applications.
HDO (1,6-Hexanediol) is preferentially used in two-component paints for plastic coatings and repair coatings.
HDO (1,6-Hexanediol) is suitable for polyester plasticizers and in soft segments for polyurethanes.
HDO (1,6-Hexanediol) shows an optimum balance of flexibility and toughness (excellent flexibility in combination with sufficient hardness) in polyesters and polyurethane.

HDO (1,6-Hexanediol) Chemical Properties
Melting point: 38-42 °C (lit.)
Boiling point: 250 °C (lit.)
Density: 0.96
Vapor pressure: 0.53 mm Hg ( 20 °C)
Refractive index: 1.457
Fp: 215 °F
Storage temp.: Store below +30°C.
Solubility H2O: 0.1 g/mL, clear, colorless
Form: Waxy Flakes
pka: 14.87±0.10(Predicted)
Color: White
PH: 7.6 (900g/l, H2O, 20℃)
Explosive limi: 6.6-16%(V)
Water Solubility: 500 g/L
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1
Merck: 14,4690
BRN: 1633461
InChIKey: XXMIOPMDWAUFGU-UHFFFAOYSA-N
LogP: 0 at 25℃
CAS DataBase Reference: 629-11-8(CAS DataBase Reference)
NIST Chemistry Reference: HDO (1,6-Hexanediol)(629-11-8)
EPA Substance Registry System: HDO (1,6-Hexanediol) (629-11-8)

Preparation
HDO (1,6-Hexanediol) is produced by a propriety process that is based on BASF technology. Industrially, HDO (1,6-Hexanediol) is prepared by the hydrogenation of adipic acid.
Conversely, in the laboratory, HDO (1,6-Hexanediol) can be synthesized by the reduction of adipic acid with lithium aluminum hydride.

Uses and Applications
HDO (1,6-Hexanediol) is used in polymer synthesis such as polyester, polyurethane and nylon.
HDO (1,6-Hexanediol) is used as an intermediate to adhesives, acrylics and dyestuffs.
Further, HDO (1,6-Hexanediol) is employed in gasoline refining and pharmaceutical production.
HDO (1,6-Hexanediol) is commonly used in polycarbonate diols, reactive diluents, saturated and unsaturated polyester resins, hot melt adhesives, and in the production of polyester polyols.
HDO (1,6-Hexanediol) is used as a chain extender in polyurethane production, creating products with mechanical strength and a high resistance to hydrolysis.
HDO (1,6-Hexanediol) is a monomer for Acrylic & Methacrylic Oligomers.
HDO (1,6-Hexanediol) is a chemical intermediate for polymeric plasticizers, surfactants, and other specialty chemicals.

Polyurethanes
HDO (1,6-Hexanediol) is widely utilized in the manufacture of polyesterols such as sebacates, azelates, and adipates.
These compounds are resistant to hydrolysis and have low glass transition temperature as well as high mechanical levels.
HDO (1,6-Hexanediol) is used as an ingredient in the preparation of a wide range of tailor-made products for numerous specialty and standard applications.

In Acrylics
HDO (1,6-Hexanediol) is utilized as an ingredient in the manufacture of the bifunctional hexanediol diacrylate which is a monomer that is normally used in conjunction with other acrylic monomers as a reactive diluent for decorative coatings and printing inks.

In Adhesives
Urethanes and co-terephthalates that are based on 1,6-hexanediol HDO (1,6-Hexanediol) provide faster better tack properties and crystallization.
Due to its low glass transition property, HDO (1,6-Hexanediol) offers high flexibility as well as excellent adhesive properties.

Other Uses
HDO (1,6-Hexanediol) is incorporated into the production of other compounds used in polymeric thickeners, sizing agents, plasticizers for polyvinyl chloride, pesticides, and surfactants dyestuffs as a flexible building block.

Synonyms
1,6-HEXANEDIOL
Hexane-1,6-diol
629-11-8
Hexamethylene glycol
1,6-Dihydroxyhexane
Hexamethylenediol
alpha,omega-Hexanediol
.alpha.,.omega.-Hexanediol
1,6-Hexylene Glycol
6-hydroxy-1-hexanol
DTXSID1027265
CHEBI:43078
NSC-508
ZIA319275I
1,1,6,6-D4-1,6-HEXANDIOL
27236-13-1
HEZ
CCRIS 8982
HSDB 6488
NSC 508
EINECS 211-074-0
BRN 1633461
UNII-ZIA319275I
AI3-03307
1,6hexanediol
1.6-hexanediol
1,6-hexandiol
1.6-hexandiol
.omega.-Hexanediol
1,6-hexane diol
1,6-hexan-diol
hexan-1,6-diol
Hexanediol-(1,6)
HEXANEDIOL [INCI]
1,6-Hexanediol, 97%
1,6-Hexanediol, 99%
EC 211-074-0
WLN: Q6Q
HO(CH2)6OH
SCHEMBL15343
CHEMBL458616
DTXCID907265
NSC508
1,6-HEXANEDIOL [HSDB]
HEXAMETHYLENE GLYCOL [MI]
Tox21_200450
MFCD00002985
AKOS003242194
CS-W011221
DB02210
NCGC00248624-01
NCGC00258004-01
AS-12686
BP-21412
CAS-629-11-8
FT-0607014
H0099
EN300-19325
1,6-Hexanediol, >=99% C6-Dioles basis (GC)
A834086
Q161563
J-504039
F0001-1701
Z104473540
InChI=1/C6H14O2/c7-5-3-1-2-4-6-8/h7-8H,1-6H
HDO 1,6-HEXANEDIOL
A diol that is hexane substituted by hydroxy groups at positions 1 and 6.
Solvent, intermediate for high polymers (nylon, polyesters), coupling agent, coil coating.
HDO 1,6-Hexanediol as a building block for resins used for adhesives providing flexibility and adhesion.

CAS: 629-11-8
MF: C6H14O2
MW: 118.17
EINECS: 211-074-0

Synonyms
HEXANE-1,6-DIOL;HEXAMETHYLENE GLYCOL;HDO(R);1,6-DIHYDROXYHEXANE;1,6-HEXANEDIOL;1,6-HDO;1,6-HEXYLENE GLYCOL;HDO 1,6-Hexanediol Flakes;1,6-HEXANEDIOL;Hexane-1,6-diol;629-11-;Hexamethylene glycol;1,6-Dihydroxyhexane;Hexamethylenediol;alpha,omega-Hexanediol;.alpha.,.omega.-Hexanediol;1,6-Hexylene Glycol;6-hydroxy-1-hexanol;DTXSID1027265;CHEBI:43078;NSC-508;ZIA319275I;1,1,6,6-D4-1,6-HEXANDIOL;27236-13-1;HEZ;CCRIS 8982;HSDB 6488;NSC 508;EINECS 211-074-0;BRN 1633461;UNII-ZIA319275I;AI3-03307;1,6hexanediol;1.6-hexanediol;1,6-hexandiol;1.6-hexandiol;.omega.-Hexanediol;1,6-hexane diol;1,6-hexan-diol;hexan-1,6-diol;Hexanediol-(1,6);HEXANEDIOL [INCI];1,6-Hexanediol, 97%;1,6-Hexanediol, 99%;EC 211-074-0;WLN: Q6Q;HO(CH2)6OH;SCHEMBL15343;CHEMBL458616;DTXCID907265;NSC508;1,6-HEXANEDIOL [HSDB];HEXAMETHYLENE GLYCOL [MI];Tox21_200450;MFCD00002985;AKOS003242194;CS-W011221;DB02210;NCGC00248624-01;AS-12686;BP-21412;CAS-629-11-8;FT-0607014;H0099;EN300-19325;1,6-Hexanediol, >=99% C6-Dioles basis (GC);A834086;Q161563;J-504039;F0001-1701;Z104473540;InChI=1/C6H14O2/c7-5-3-1-2-4-6-8/h7-8H,1-6H

HDO 1,6-Hexanediol is a waxy hygroscopic solid compound that is white in colour.
HDO 1,6-Hexanediol is a linear diol that contains two primary hydroxyl groups that are located at the terminal.
HDO 1,6-Hexanediol’s linear hydrocarbon chain enables the compound to have enhanced hardness and flexibility of polyesters.
Moreover, this property is utilized in the extending chains in polyurethanes.
HDO 1,6-Hexanediol is also applied in the manufacturing process of radiation-curable coatings, polycarbonate diols and as a reactive thinner for the formulation of epoxy systems which are used for the efficient production of rotor blades for modern wind turbines.
HDO 1,6-Hexanediol as a building block for the production of polyester and polyurethane resins.
Good balance between hardness and flexibility, adhesion, weatherability or hydrolysis resistance.

HDO 1,6-Hexanediol is an organic compound with the formula (CH2CH2CH2OH)2.
HDO 1,6-Hexanediol is a colorless water-soluble solid.[3]
HDO 1,6-Hexanediol is straight-chained, bifunctional primary alcohol.
HDO 1,6-Hexanediol is a white waxy solid at room temperature and has a melting point of 42°C.
HDO 1,6-Hexanediol dissolves in a wide variety of organic solvents and water.
HDO 1,6-Hexanediol is an organic compound with the formula HOCH2(CH2)4CH2OH.
The structure is as follows:
HDO 1,6-Hexanediol is commonly used in polycarbonate diols, reactive diluents, saturated and unsaturated polyester resins, hot melt adhesives, and in the production of polyester polyols.
HDO 1,6-Hexanediol is used as a chain extender in polyurethane production, creating products with mechanical strength and a high resistance to hydrolysis.
HDO 1,6-Hexanediol is a monomer for Acrylic & Methacrylic Oligomers.
HDO 1,6-Hexanediol is a chemical intermediate for polymeric plasticizers, surfactants, and other specialty chemicals.

HDO 1,6-Hexanediol is a building block for saturated polyesters and polyurethanes acrylic esters of HDO 1,6-Hexanediol are used as reactive diluent for UV-coatings.
HDO 1,6-Hexanediol is used in polyesters for solvent-borne paints, in stoving enamels for automotive coatings, for can-& coil-coating and for general applications.
HDO 1,6-Hexanediol is preferentially used in two-component paints for plastic coatings and repair coatings.
HDO 1,6-Hexanediol is suitable for polyester plasticizers and in soft segments for polyurethanes.

HDO 1,6-Hexanediol Chemical Properties
Melting point: 38-42 °C (lit.)
Boiling point: 250 °C (lit.)
Density: 0.96
Vapor pressure: 0.53 mm Hg ( 20 °C)
Refractive index: 1.457
Fp: 215 °F
Storage temp.: Store below +30°C.
Solubility H2O: 0.1 g/mL, clear, colorless
Form: Waxy Flakes
pka: 14.87±0.10(Predicted)
Color: White
PH: 7.6 (900g/l, H2O, 20℃)
Explosive limit: 6.6-16%(V)
Water Solubility: 500 g/L
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1
Merck: 14,4690
BRN: 1633461
InChIKey: XXMIOPMDWAUFGU-UHFFFAOYSA-N
LogP: 0 at 25℃
CAS DataBase Reference: 629-11-8(CAS DataBase Reference)
NIST Chemistry Reference: HDO 1,6-Hexanediol(629-11-8)
EPA Substance Registry System: HDO 1,6-Hexanediol (629-11-8)

As HDO 1,6-Hexanediol contains the hydroxyl group, it undergoes the typical chemical reactions of alcohols such as dehydration, substitution, esterification.
Dehydration of HDO 1,6-Hexanediol gives oxepane, 2-methyltetrahydropyran and 2-ethyltetrahydrofuran.
Corresponding thiophene and pyrrolidone can be made by reacting HDO 1,6-Hexanediol with hydrogen sulfide and ammonia respectively.

Uses and Applications
HDO 1,6-Hexanediol is used in polymer synthesis such as polyester, polyurethane and nylon.
HDO 1,6-Hexanediol is used as an intermediate to adhesives, acrylics and dyestuffs.
Further, HDO 1,6-Hexanediol is employed in gasoline refining and pharmaceutical production.

HDO 1,6-Hexanediol can be used for a variety of applications such as:
a structure-directing agent for the synthesis of ZSM-5 zeolite
a solvent for titanium tetraisopropoxide to form titanium oxide (TiO2) nanocrystals
a phase change material in combination with lauric acid for thermal energy storage applications

HDO 1,6-Hexanediol is widely used for industrial polyester and polyurethane production.
HDO 1,6-Hexanediol can improve the hardness and flexibility of polyesters as it contains a fairly long hydrocarbon chain.
In polyurethanes, HDO 1,6-Hexanediol is used as a chain extender, and the resulting modified polyurethane has high resistance to hydrolysis as well as mechanical strength, but with a low glass transition temperature.
HDO 1,6-Hexanediol is also an intermediate to acrylics as a crosslinking agent, e.g. hexanediol diacrylate.
Unsaturated polyester resins have also been made from HDO 1,6-Hexanediol, along with styrene, maleic anhydride and fumaric acid.

Uses to study biomolecular condensates
HDO 1,6-Hexanediol has been used to characterize biomolecular condensates.
The material properties of condensates can be examined to determine if they are solid or liquid condensates.
HDO 1,6-Hexanediol has been reported to interfere with weak hydrophobic protein-protein or protein-RNA interactions that comprise liquid condensates.
HDO 1,6-Hexanediol has been reported to dissolve liquid but not solid condensates.
2,5 hexanediol or 1,4-butanediol has been observed to have minimal effect on behavior of disorderd proteins as compared to HDO 1,6-Hexanediol.

Polyurethanes
HDO 1,6-Hexanediol is widely utilized in the manufacture of polyesterols such as sebacates, azelates, and adipates.
These compounds are resistant to hydrolysis and have low glass transition temperature as well as high mechanical levels.
HDO 1,6-Hexanediol is used as an ingredient in the preparation of a wide range of tailor-made products for numerous specialty and standard applications.

In Acrylics
HDO 1,6-Hexanediol is utilized as an ingredient in the manufacture of the bifunctional hexanediol diacrylate which is a monomer that is normally used in conjunction with other acrylic monomers as a reactive diluent for decorative coatings and printing inks.

In Adhesives
Urethanes and co-terephthalates that are based on HDO 1,6-Hexanediol provide faster better tack properties and crystallization.
Due to its low glass transition property, HDO 1,6-Hexanediol offers high flexibility as well as excellent adhesive properties.

Other Uses
HDO 1,6-Hexanediol is incorporated into the production of other compounds used in polymeric thickeners, sizing agents, plasticizers for polyvinyl chloride, pesticides, and surfactants dyestuffs as a flexible building block.

Quality and Analysis
The assay of the pure product is about 98 %; impurities are various diols and -caprolactone as well as traces of water.
The color number of the product determined photometrically according to the Pt/Co scale must not exceed 15 APHA.
Above 70 ℃, HDO 1,6-Hexanediol tends to turn yellow.

Preparation
HDO 1,6-Hexanediol is produced by a propriety process that is based on BASF technology.
Industrially, HDO 1,6-Hexanediol is prepared by the hydrogenation of adipic acid.
Conversely, in the laboratory, HDO 1,6-Hexanediol can be synthesized by the reduction of adipic acid with lithium aluminum hydride.
HDO 1,6-Hexanediol is prepared by the hydrogenation of adipic acid or its esters.
Laboratory preparation could be achieved by reduction of adipates with lithium aluminium hydride, although this method is impractical on a commercial scale.

Production Methods
HDO 1,6-Hexanediol is produced industrially by the catalytic hydrogenation of adipic acid or of its esters.
Mixtures of dicarboxylic acids and hydroxycarboxylic acids with C6 components formed in other processes (e.g., in cyclohexane oxidation) are also used.
Esterifification of "distillation heavies" with lower alcohols is often carried out before hydrogenation.
The acids are hydrogenated continuously at 170-240 ℃ and at 15.0-30.0 MPa on a suitable catalyst either in a trickle-flflow (downflflow) or a bubble-flflow (upflflow) fifixed-bed reactor.
The reactor temperature is controlled by circulating part of the reactor discharge.

The hydrogen required for the hydrogenation is fed together with the recycle gas through the recycle gas compressor to the reactor.
Side products of the synthesis are alcohols, ethers, diols, and esters.
Pure HDO 1,6-Hexanediol is obtained by fractional distillation of the crude reactor discharge.
For the hydrogenation of dicarboxylic acids, catalysts containing cobalt, copper, or manganese are suitable.
For the hydrogenation of esters, catalysts such as copper chromite or copper with added zinc and barium are used as "full catalysts" or on inert carriers.
Ruthenium, platinum, or palladium on inert supports can also be used.
Gas-phase hydrogenation of esters of adipic or 6-hydroxyhexanoic acid can be carried out at 1-7 MPa.
Both acids and esters also may be hydrogenated using suspended catalysts.
Oligomeric esters of the product diol and adipic acid can also be hydrogenated.
HE SHOU WU (FO-TI) EXTRACT

He Shou Wu, also known as Fo-Ti, is derived from the root of the Polygonum multiflorum plant and is revered for its anti-aging, hair health, and vitality-boosting properties.
He Shou Wu (Fo-Ti) Extract is widely recognized for its ability to promote hair growth, improve hair pigmentation, and support longevity, making it a valuable ingredient in beauty and wellness formulations.
This versatile extract offers both therapeutic and wellness benefits, helping to maintain healthy hair, restore vitality, and support overall well-being.

CAS Number: 84931-69-1
EC Number: 284-510-0

Synonyms: He Shou Wu Extract, Fo-Ti Extract, Polygonum multiflorum Extract, Chinese Knotweed Extract, Fo-Ti Root Extract, Ho Shou Wu Extract, Polygonum Extract, Shou Wu Bioactive Extract, Fo-Ti Phytocomplex, Fo-Ti Herbal Extract, He Shou Wu Anti-Aging Extract



APPLICATIONS


He Shou Wu (Fo-Ti) Extract is extensively used in hair care products, promoting hair growth and restoring natural hair pigmentation.
He Shou Wu (Fo-Ti) Extract is favored in the creation of anti-aging supplements, where it helps to slow the effects of aging and promote longevity.
He Shou Wu (Fo-Ti) Extract is utilized in the development of vitality-boosting formulations, providing natural energy enhancement and vitality restoration.

He Shou Wu (Fo-Ti) Extract is widely used in supplements designed to support hair health, helping to strengthen hair follicles and promote healthy hair growth.
He Shou Wu (Fo-Ti) Extract is employed in the formulation of anti-aging skincare products, offering benefits for reducing the appearance of fine lines and supporting youthful skin.
He Shou Wu (Fo-Ti) Extract is essential in the creation of wellness products that promote overall vitality, energy, and longevity.

He Shou Wu (Fo-Ti) Extract is utilized in the production of natural hair dyes and treatments, restoring natural hair color and preventing premature graying.
He Shou Wu (Fo-Ti) Extract is a key ingredient in holistic hair care formulas, providing nourishment and strengthening benefits for hair and scalp health.
He Shou Wu (Fo-Ti) Extract is used in the development of hair restoration supplements, helping to address hair thinning and promote fuller, healthier hair.

He Shou Wu (Fo-Ti) Extract is applied in the formulation of vitality supplements, supporting healthy energy levels and promoting overall wellness.
He Shou Wu (Fo-Ti) Extract is employed in the creation of beauty supplements, where it helps to improve hair and skin health, as well as slow the aging process.
He Shou Wu (Fo-Ti) Extract is used in the development of anti-aging elixirs, promoting youthful vitality and helping to combat the effects of aging.

He Shou Wu (Fo-Ti) Extract is widely utilized in the formulation of energy-boosting supplements, offering natural vitality enhancement and improved stamina.
He Shou Wu (Fo-Ti) Extract is a key component in hair-strengthening treatments, where it helps to fortify hair follicles and improve scalp health.
He Shou Wu (Fo-Ti) Extract is used in the production of natural remedies for restoring hair pigmentation and reducing premature graying.

He Shou Wu (Fo-Ti) Extract is employed in the formulation of vitality teas, supporting overall energy balance and longevity.
He Shou Wu (Fo-Ti) Extract is applied in the creation of dietary supplements designed to promote hair growth and restore natural hair color.
He Shou Wu (Fo-Ti) Extract is utilized in the development of wellness beverages, promoting vitality and longevity while supporting hair and skin health.

He Shou Wu (Fo-Ti) Extract is found in the formulation of vitality capsules, providing support for healthy hair, energy, and anti-aging.
He Shou Wu (Fo-Ti) Extract is used in the production of herbal beauty supplements, offering benefits for youthful skin and healthy hair growth.
He Shou Wu (Fo-Ti) Extract is a key ingredient in longevity supplements, providing natural support for aging gracefully and maintaining vitality.



DESCRIPTION


He Shou Wu, also known as Fo-Ti, is derived from the root of the Polygonum multiflorum plant and is revered for its anti-aging, hair health, and vitality-boosting properties.
He Shou Wu (Fo-Ti) Extract is widely recognized for its ability to promote hair growth, improve hair pigmentation, and support longevity, making it a valuable ingredient in beauty and wellness formulations.

He Shou Wu (Fo-Ti) Extract offers additional benefits such as improving skin vitality, promoting healthy aging, and restoring energy balance.
He Shou Wu (Fo-Ti) Extract is often incorporated into formulations designed to promote hair growth, reduce hair thinning, and restore natural hair pigmentation.
He Shou Wu (Fo-Ti) Extract is recognized for its ability to enhance overall vitality, helping to combat the effects of aging and restore youthful energy.

He Shou Wu (Fo-Ti) Extract is commonly used in both traditional and innovative wellness formulations, providing a reliable solution for maintaining healthy hair and vitality.
He Shou Wu (Fo-Ti) Extract is valued for its ability to support the body's natural rejuvenation processes, making it a key ingredient in products that aim to promote longevity and slow the aging process.
He Shou Wu (Fo-Ti) Extract is a versatile ingredient that can be used in a variety of products, including hair care, supplements, and wellness beverages.

He Shou Wu (Fo-Ti) Extract is an ideal choice for products targeting hair growth, vitality restoration, and anti-aging, providing natural and effective support for these concerns.
He Shou Wu (Fo-Ti) Extract is known for its compatibility with other hair- and vitality-supporting ingredients, making it easy to integrate into multi-functional formulations.
He Shou Wu (Fo-Ti) Extract is often chosen for formulations requiring a balance between hair health, anti-aging, and energy restoration, ensuring comprehensive wellness benefits.

He Shou Wu (Fo-Ti) Extract enhances the overall effectiveness of beauty and wellness products by providing natural support for hair health, vitality, and anti-aging.
He Shou Wu (Fo-Ti) Extract is a reliable ingredient for creating products that offer noticeable improvements in hair growth, pigmentation, and overall vitality.
He Shou Wu (Fo-Ti) Extract is an essential component in innovative wellness products known for their performance, safety, and ability to support healthy aging and hair restoration.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: He Shou Wu Extract (Polygonum multiflorum Extract)
Molecular Structure:
Appearance: Brown powder or liquid extract
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If He Shou Wu Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If He Shou Wu Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of He Shou Wu Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling He Shou Wu Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store He Shou Wu Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.

HEC
Hydroxyethyl Cellulose; Hydroxyethyl cellulose ether; Hydroxyethyl ether cellulose; Natrosol; Natrosol 240JR; Natrosol 250 H; Natrosol 250 HHR; Natrosol 250 M; Natrosol L 250; Natrosol LR; HEC CAS NO.:9004-62-0
HEC HYDROXYETHYL CELLULOSE
hydroxyethyl cellulose; cellulose, 2-hydroxyethyl ether; cellulose ether; cellulose ethylene oxide-grafted; cellulose hydroxyethyl ether; hydroxyethylcellulose; natrosol; tylose cas no:9004-62-0
HECTORITE GEL

Hectorite gel is a suspension of Hectorite gel in water or another liquid medium, often used in various industrial and cosmetic applications due to its rheological properties.
Hectorite itself is a type of smectite clay mineral, similar to bentonite, but with a different chemical composition.
Hectorite gel is a naturally occurring clay composed primarily of magnesium, lithium, and silicate.

Synonyms: Hectorite, Hectorite clay, Lithium magnesium silicate, Laponite, Hectorite mineral, Magnesium lithium silicate, Sodium hectorite, Smectite clay, Montmorillonite, Rheological clay, Clay gel, Natural clay, Mineral gel, Bentonite substitute, Rheological additive, Cosmetic clay, Industrial clay, Thixotropic clay, Smectite mineral, Suspension clay, Natural rheological agent, Hectorite gel, Hectorite suspension, Thickening clay, Stabilizing clay, Hectorite powder, Cosmetic thickener, Skin care clay, Facial mask clay, Bentonite alternative, Clay-based gel, Clay mineral, Hectorite derivative, Modified hectorite, Organically modified clay, Hectorite dispersion, Hectorite complex, Silicate mineral, Hectorite colloid, Hectorite suspension agent, Hectorite thickener, Hectorite stabilizer, Hectorite binder, Hectorite flocculant, Hectorite emulsifier, Hectorite flocculating agent, Hectorite suspending agent, Hectorite rheology modifier, Hectorite viscosity agent, Hectorite paste, Hectorite slurry, Hectorite emulsion, Hectorite stabilizing agent, Hectorite thickening agent



APPLICATIONS


Hectorite gel is extensively used in the cosmetics industry as a thickening and stabilizing agent.
Hectorite gel is a key ingredient in facial masks, where it helps to impart a smooth texture and enhance spreadability.

In skincare products, Hectorite gel is utilized for its ability to absorb excess oil and impurities from the skin.
Hectorite gel is employed in creams and lotions to improve consistency and provide a silky feel upon application.

Hectorite gel serves as a suspending agent in formulations where it helps to evenly distribute particles and ingredients.
In hair care products, Hectorite gel is used in styling gels and clays to add volume and provide hold.

Hectorite gel's thixotropic nature makes it valuable in products like toothpaste, ensuring proper viscosity and flow properties.
Hectorite gel finds applications in the pharmaceutical industry as an excipient in topical formulations such as ointments and creams.

Hectorite gel contributes to the stability and texture of pharmaceutical products, aiding in their efficacy and patient compliance.
In the food industry, Hectorite gel may be used as a stabilizer and thickener in certain food products and beverages.

Hectorite gel is utilized in the manufacture of paints and coatings to control viscosity and improve application properties.
Hectorite gel is added to drilling fluids in the oil and gas industry to enhance fluid viscosity and suspend solids during drilling operations.

Hectorite gel's ability to swell and form gels makes it useful in the production of adhesives and sealants.
Hectorite gel is incorporated into agricultural formulations to improve the delivery and efficacy of pesticides and fertilizers.

Hectorite gel is employed in ceramics and pottery as a plasticizer, enhancing the workability of clay bodies.
Hectorite gel is used in the production of rubber compounds to improve processing and mechanical properties.
Hectorite gel's natural origin and inert nature make it suitable for use in environmentally sensitive applications.

In textile manufacturing, Hectorite gel may be used as a sizing agent to improve fabric strength and durability.
Hectorite gel serves as a binder and stabilizer in the construction industry, enhancing the performance of cementitious materials.

Hectorite gel is utilized in personal care products such as deodorants and antiperspirants for its absorbent properties.
Hectorite gel is added to paints and coatings to improve rheological control and prevent sagging or dripping.

Hectorite gel is used in the formulation of household and industrial cleaners to enhance cleaning efficiency.
In the plastics industry, Hectorite gel serves as a reinforcing filler, improving the strength and dimensional stability of plastic composites.

Hectorite gel's ability to form stable suspensions makes it valuable in the formulation of pharmaceutical suspensions and emulsions.
Hectorite gel is valued for its versatility across multiple industries, contributing to the functionality, performance, and sensory attributes of various products.

Hectorite gel is used in the formulation of sunscreen lotions and creams to improve their texture and spreadability while providing enhanced UV protection.
Hectorite gel is added to deodorants and antiperspirants to enhance product stability and improve the feel upon application.
In the paint and coating industry, Hectorite gel serves as a rheological modifier to control viscosity and prevent settling of pigments.

Hectorite gel's ability to form stable dispersions makes it suitable for use in ink formulations, improving print quality and color intensity.
Hectorite gel is utilized in the production of ceramics as a binder and plasticizer, facilitating shaping and drying processes.
Hectorite gel is incorporated into foundry sands to enhance moldability and improve the surface finish of castings.

Hectorite gel finds applications in the fabrication of catalyst supports and adsorbents due to its high surface area and porosity.
Hectorite gel is used in the construction industry to improve the workability and durability of mortar and concrete mixes.

In the automotive sector, Hectorite gel is added to lubricating greases to enhance their thickening ability and mechanical stability.
Hectorite gel serves as a carrier for active ingredients in controlled-release formulations, prolonging the efficacy of agricultural pesticides and herbicides.

Hectorite gel is utilized in the formulation of wound dressings and bandages for its moisture-retentive and biocompatible properties.
Hectorite gel is employed in the production of rubber products to improve processing characteristics and enhance the strength of elastomers.

Hectorite gel is used in the cosmetics industry to stabilize emulsions and improve the shelf life of creams, lotions, and serums.
Hectorite gel serves as a suspension agent in paints and coatings to prevent settling of pigments and improve application properties.

Hectorite gel is added to drilling muds in the mining and oil drilling industries to control viscosity and provide lubrication.
Hectorite gel's ability to absorb oils and contaminants makes it suitable for use in environmental cleanup applications.
Hectorite gel is utilized in the formulation of household cleaners to enhance their cleaning efficacy and provide a smooth texture.

In the textile industry, the clay is used as a sizing agent to improve the strength and durability of fabrics.
Hectorite gel serves as a carrier for fragrances and essential oils in perfumes and aromatherapy products, providing prolonged scent release.
Hectorite gel is used in the manufacture of paper and cardboard to improve sheet formation and enhance printability.

Hectorite gel's ability to stabilize suspensions makes it valuable in the formulation of pharmaceuticals, ensuring uniform distribution of active ingredients.
Hectorite gel is incorporated into personal care products such as bath salts and scrubs for its gentle exfoliating and cleansing properties.
Hectorite gel is used in the formulation of pet care products such as shampoos and conditioners to enhance coat texture and manageability.

Hectorite gel is employed in the production of ceramics and pottery glazes to improve adhesion and surface finish.
Hectorite gel continues to find diverse applications across industries, contributing to the performance, functionality, and sustainability of various products and processes.

Hectorite gel serves as a thickening agent in adhesives and sealants, improving their adhesive properties.
Hectorite gel is compatible with a wide range of organic and inorganic materials, making Hectorite gel versatile in various formulations.
In the food industry, Hectorite gel may be used as a stabilizer and thickener in certain food products.

Hectorite gel's natural origin and non-toxic nature make it suitable for use in environmentally sensitive applications.
Hectorite gel is processed into various forms including powders, pastes, and dispersions for ease of application.

Hectorite gel is known for its ability to impart a soft, velvety feel to cosmetic products.
Hectorite gel is inert under normal conditions and exhibits good chemical stability.

Hectorite gel's ability to form stable gels makes it valuable in the formulation of suspensions and emulsions.
Cosmetic products containing Hectorite gel often promote smoother application and enhanced product performance.

In pharmaceuticals, Hectorite gel aids in the controlled release of active ingredients from topical formulations.
Hectorite gel's swelling properties are utilized to improve the texture and consistency of personal care products.

Hectorite gel is mined from deposits around the world and undergoes purification and processing for commercial use.
Hectorite gel is prized for its rheological benefits and its ability to enhance the functionality and sensory experience of various products.



DESCRIPTION


Hectorite gel is a suspension of Hectorite gel in water or another liquid medium, often used in various industrial and cosmetic applications due to its rheological properties.
Hectorite itself is a type of smectite clay mineral, similar to bentonite, but with a different chemical composition.
Hectorite gel is a naturally occurring clay composed primarily of magnesium, lithium, and silicate.

Hectorite gel is a naturally occurring mineral known for its unique rheological properties.
Hectorite gel belongs to the smectite group of clays and is composed primarily of magnesium, lithium, and silicate.

Hectorite gel has a fine, smooth texture and a creamy white appearance.
Hectorite gel is characterized by its ability to swell significantly when exposed to water, forming a gel-like consistency.

Hectorite gel exhibits thixotropic behavior, meaning it becomes less viscous when agitated and returns to a gel-like state when at rest.
Hectorite gel is widely used in cosmetic formulations as a thickener and stabilizer.
Hectorite gel enhances the texture and spreadability of creams, lotions, and masks in skincare products.

In makeup products, Hectorite gel helps to create smooth and creamy textures.
Hectorite gel is valued for its ability to suspend particles and stabilize emulsions in cosmetic formulations.
Hectorite gel is used in pharmaceutical applications as an excipient in topical medications and ointments.

In the industrial sector, Hectorite gel is utilized as a rheological additive in paints, coatings, and drilling fluids.
Due to its high swelling capacity, Hectorite gel is effective in controlling viscosity and fluid loss in drilling operations.



PROPERTIES


Physical Properties

Appearance: Fine, creamy white to light gray powder or gel.
Texture: Smooth and silky.
Odor: Odorless.
Density: Typically ranges from 1.8 to 2.5 g/cm³.
Particle Size: Average particle size varies, often in the micrometer range.
Solubility: Insoluble in water and organic solvents.
pH: Generally neutral (around 7).
Specific Surface Area: Typically has a high specific surface area due to its layered structure.
Porosity: Exhibits porosity due to its layered crystalline structure.
Thermal Stability: Stable up to temperatures around 500-600°C.
Optical Properties: Exhibits a characteristic birefringence under polarized light due to its layered structure.


Chemical Properties

Composition: Primarily consists of magnesium, lithium, silicon, oxygen, and hydroxyl groups.
Layer Structure: Hectorite belongs to the smectite group of clays, characterized by a layered silicate structure.
Cation Exchange Capacity (CEC): Exhibits high CEC due to the presence of exchangeable cations in the interlayer spaces.
Ion Exchange Properties: Capable of exchanging cations such as sodium, calcium, and potassium in aqueous solutions.
Rheological Properties: Displays thixotropic behavior, becoming less viscous when agitated and returning to a more viscous state when at rest.
Swelling Properties: Swells significantly upon hydration, forming stable gels or suspensions.
Adsorption Capacity: Has the ability to adsorb and retain molecules and ions on its surface and within its interlayer spaces.
Mechanical Properties: Exhibits plasticity and moldability when mixed with water, contributing to its use in various applications.
Chemical Stability: Generally stable under normal environmental conditions; inert towards most chemicals and acids.



FIRST AID


Inhalation

Move to fresh air:
If inhaled, move the affected person to fresh air to avoid further exposure.

Monitor breathing:
If breathing difficulties occur, seek medical attention immediately.

Provide oxygen:
If breathing is difficult, administer oxygen if trained to do so.


Skin Contact

Remove contaminated clothing:
Remove any contaminated clothing and shoes promptly.

Wash skin thoroughly:
Wash affected skin with soap and water.
Avoid using harsh chemicals that may exacerbate irritation.

Seek medical attention:
If irritation develops or persists, seek medical advice.


Eye Contact

Flush with water:
Immediately flush eyes with gently flowing water for at least 15 minutes, ensuring eyelids are held open to facilitate rinsing.

Remove contact lenses:
If present and easy to do, remove contact lenses after the initial rinse.

Seek medical attention:
If irritation, redness, or pain persists, seek medical evaluation.


Ingestion
Do not induce vomiting:
Do not induce vomiting unless instructed to do so by medical personnel.

Rinse mouth:
Rinse mouth thoroughly with water.

Seek medical attention:
Seek medical advice or attention immediately.
Provide medical personnel with the SDS or product label information.



HANDLING AND STORAGE


Handling

Handling Precautions

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves, safety goggles, and protective clothing, to prevent skin and eye contact.
Use respiratory protection if handling in dusty conditions.

Avoid Inhalation:
Avoid breathing dust or aerosols. Use local exhaust ventilation or wear respiratory protection if dust generation is likely.

Minimize Dust Generation:
Handle Hectorite gel in a manner that minimizes dust formation.
Use dust suppression methods such as wet sweeping or vacuuming with HEPA-filtered equipment.

Avoid Contact with Eyes and Skin:
Prevent contact with eyes and skin.
In case of contact, promptly rinse affected area with water and remove contaminated clothing.

Avoid Ingestion:
Do not ingest Hectorite gel.
Wash hands thoroughly after handling and before eating, drinking, or smoking.

Static Electricity:
Handle and store Hectorite gel away from sources of static electricity to prevent accumulation and discharge.


Safe Handling Instructions

Use in Well-Ventilated Areas:
Use Hectorite gel in well-ventilated areas to minimize exposure to airborne particles.

Storage of Containers:
Keep containers tightly closed when not in use to prevent contamination and moisture absorption.

Labeling:
Ensure containers are labeled properly with product name, hazard information, and handling precautions.

Transfer Procedures:
Use appropriate equipment and containers designed for handling powders to minimize dust generation during transfer operations.

Spill Cleanup:
In case of spills, use appropriate absorbent materials to contain and clean up Hectorite gel.
Avoid generating dust.
Dispose of contaminated materials properly.


Storage

Storage Conditions

Store in a Dry Location:
Store Hectorite gel in a cool, dry place away from moisture and humidity to prevent clumping and degradation.

Temperature Control:
Maintain storage temperatures within recommended limits (typically room temperature) to ensure product stability.

Avoid Direct Sunlight:
Store containers away from direct sunlight and heat sources to prevent temperature fluctuations.

Compatibility:
Store Hectorite gel away from incompatible materials, including strong acids, bases, and oxidizing agents, to avoid reactions or contamination.

Ventilation:
Ensure adequate ventilation in storage areas to prevent accumulation of airborne particles and maintain air quality.


Specific Handling and Storage Considerations

Moisture Sensitivity:
Hectorite gel is sensitive to moisture and can absorb water, affecting its properties. Keep containers tightly closed when not in use.

Packaging Compatibility:
Use containers made of compatible materials such as polyethylene or stainless steel to store Hectorite gel safely.

Storage Stability:
Properly stored Hectorite gel maintains its chemical and physical properties over extended periods.
Check for signs of degradation or contamination before use.

Segregation:
Store Hectorite gel away from food and feedstuffs to prevent accidental ingestion and cross-contamination.

Emergency Response:
Have spill control measures and emergency response procedures in place.
Train personnel on proper handling and emergency protocols.
HECTORITE GEL
Hectorite Gel is very versatile dispersion of hectorite blended with triglyceride for adding viscosity of oil-phase systems.
Hectorite Gel is a natural, soft, greasy, white clay mineral occurring in volcanic ash and tuff.
Hectorite Gel is light tan colored (buff) thick gel.


CAS: 73398-61-5, 12691-60-0, 108-32-7
INCI Name: Caprylic/Capric Triglyceride (and) Stearalkonium Hectorite (and) Propylene Carbonate



SYNONYMS:
Octyldodecanol, Disteardimonium Hectorite, Propylene Carbonate



Add Hectorite Gel to oil-phase of formulas; mix into low amounts of oils to overcome large viscosity differences.
Hectorite Gel is best to add the gel under agitation to a portion of the fatty components.
Mix Hectorite Gel until the mixture becomes homogeneous before adding any other ingredients.


Typical use level of Hectorite Gel is 2.5-10%.
Hectorite Gel is very versatile dispersion of hectorite blended with triglyceride for adding viscosity of oil-phase systems.
Hectorite Gel is a natural, soft, greasy, white clay mineral occurring in volcanic ash and tuff.


Hectorite Gel is light tan colored (buff) thick gel.
Viscosity of Hectorite Gel is 1.5-3.2 cps. Not water-soluble. Miscible with oils.
Hectorite Gel is a very versatile dispersion of hectorite blended with triglyceride for adding viscosity of oil-phase systems.


Viscosity of Hectorite Gel is 1.5-3.2 cps.
Hectorite Gel is a natural, soft, greasy, white clay mineral occurring in volcanic ash and tuff.
Hectorite Gel is very versatile dispersion of hectorite blended with triglyceride for adding viscosity of oil-phase systems.


Hectorite Gel is a natural, soft, greasy, white clay mineral occurring in volcanic ash and tuff.
Hectorite Gel is a gelling agent for the oil.
Hectorite Gel is suitable for use in makeup formulations. or any kind of cosmetics with a mixture of essential oils.


Hectorite Gel is developed specifically to hold (suspend) pigment pigments in formulas for even distribution of pigments in all types of make-up.
Hectorite Gel is a smectite clay mineral obtained from the hectorite mine in California, USA, which is the largest and the purest clay and with high purity Makes it whiter and smoother.


Compared to other types of clays Hectorite Gel can act as a thickener for oils, such as Bentonite.
Hectorite Gel has the ability to bind (suspension) pigments, pearl powders and other shimmering powders into the formula without precipitation and make the color spread completely.


Hectorite Gel is produced by hectorite Organoclay powder.
Hectorite Gel is a specially prepared dispersion of a non-animal origin organically modified hectorite in Caprylic/Capric Triglyceride.
This grade of Hectorite Gel is designed to impart rheological control and suspension to organic- and silicone-based cosmetics.


There is good suspension when Hectorite Gel uses oil drilling mud and fracture.
Hectorite Gel is classified as a smectite clay mineral gotten from the Hectorite mine, where it is the biggest and also the purest clay.
When Hectorite Gel is compared with other clay types it can act as a thickener for oils such as Bentonite, as well as with a high pureness Making it a milklike white as well as smoother.


Popular item qualities Hectorite Gel produces a gel-like appearance, such as Lip Gel, Lip Gloss.
Since Hectorite Gel is highly efficient in holding (suspension) pigments, pearl powders and shimmering powders right into the formula.
Hectorite Gel is a thickener to create a gel texture.


Blending approach of Hectorite Gel: Mix in oil and mix well.
Hectorite Gel will turn the oil right into a gel structure
Hectorite Gel can liquefy in oil.


Hectorite Gel is a non-animal origin rheological additive for cosmetics and toiletries.
Hectorite Gel is a specially prepared dispersion of an organically modified hectorite in caprylic/capric triglyceride.
Hectorite Gel offers rheological control and suspension to organic- and silicone-based cosmetics.


Hectorite Gel is a non-abrasive ingredient which provides thermostable viscosity control of the emulsion's oil phase and improves application properties.
Hectorite Gel provides a soft, smooth, non-tacky, non-greasy and residual silky feel to skin.
Hectorite Gel offers improved application properties as well as predictable, reproducible, stable, thermostable and shear thinning viscosity control of the emulsion's oil phase.


Hectorite Gel controls alignment of special-effect pigments and gives excellent suspension of pigments & actives.
Hectorite Gel increases apparent melting point and ensures cost-efficient use of UV filters.
Hectorite Gel is suitable for cold process systems.


Hectorite Gel provides emulsion stabilization [w/o and o/w] and provides a high degree of formulating flexibility.
Hectorite Gel is used in antiperspirants, skin- & sun care products, eye shadow, foundations and lip products.
Hectorite Gel is RSPO approved.


The shelf life of Hectorite Gel is 2 years.
Hectorite Gel is a dispersion of Hectorite modified into Octyldodecanol created to provide rheological control to cosmetics.
Hectorite Gel can be introduced into various cosmetic products: creams and lotions, sun products, make up, deodorants, hair products, ointments, oil-gels, sticks.



USES and APPLICATIONS of HECTORITE GEL:
Hectorite Gel can be used hot or cold to thicken oil phase systems.
Hectorite Gel provides viscosity control.
Hectorite Gel enhances skin feel by masking greasy or tacky components.


Hectorite Gel provides softness and silkiness to the skin and color cosmetics.
Hectorite Gel possesses shear-thinning viscosity.
Hectorite Gel is excellent suspension of pigments, actives and controlled alignment of special-effect pigments.


Hectorite Gel can be used hot or cold to thicken oil phase systems
Hectorite Gel provides viscosity control
Hectorite Gel enhances skin feel by masking greasy or tacky components


Hectorite Gel provides softness and silkiness to the skin and color cosmetics
Hectorite Gel possesses shear-thinning viscosity
Hectorite Gel is excellent suspension of pigments, actives and controlled alignment of special-effect pigments


Hectorite Gel is used for external use only.
Hectorite Gel is used emulsions (creams, lotions), sun care, mascara, lip color, lip glosses, massage gels.
Hectorite Gel is also particularly useful in emulsions and can be used in "cold process" systems.


Hectorite Gel provides thermostable viscosity control of the emulsion's oil phase, improves application properties, enhances skin-feel by masking greasy or tacky components and imparts a pleasant residual silkiness to the skin.
Hectorite Gel is an alternative to traditional polymer or cellulose-based thickeners for stabilizing emulsions.


Hectorite Gel is used Anti-Perspirants, Skin Care Products, Sun Care Products, Lip Products, Eye Shadow, Foundations.
Hectorite Gel is used ingredients to produce a gel to the oil.
Hectorite Gel is used for use in makeup solutions Or any type of kind of cosmetics Which is a cornerstone of oil Very capable of holding (suspension) pigment, pearl powder and also different shimmering powders in the formula.


Without working out And make the color entirely dispersed.
Hectorite Gel is a gelling representative for oils.
Hectorite Gel is ideal for use in make-up solutions or any type of cosmetics


Hectorite Gel is a main ingredient of oil Established especially for suspended pigments in solutions for uniformly distributed pigments in all make-ups.
Hectorite Gel provides a thixotropic thickness, meaning that when the shear force is applied, the viscosity of the compound is minimized.
However when the thickness is stopped, Hectorite Gel will go back to its initial state.


Hectorite Gel is classed as a flow characteristic that appropriates for all kinds of make-up, specifically any kind of kind of make-up.
Hectorite Gel is used additives to develop a gel to the oil.
Hectorite Gel is a gelling representative for oils.


Popular item qualities Hectorite Gel creates a gel-like texture, such as Lip Gel, Lip Gloss.
Since Hectorite Gel is very capable of holding (suspension) pigments, pearl powders and sparkling powders right into the formula.
Hectorite Gel is used emulsions (creams, lotions), sun care, mascara, lip color, lip glosses, massage gels.


Hectorite Gel is used for non-polar or less polar oils such as Mineral Oil, Isododecane
Hectorite Gel is used Foundation, Eye Mascara, Lip Stick, Body Powder, Creams & Lotions, and UV Sunscreen.
Hectorite Gel is used to add to the oil-phase of formulas; mix into low amounts of oils to overcome large viscosity differences.


Hectorite Gel is used for external use only.
Applications of Hectorite Gel: Emulsions (creams, lotions), sun care, mascara, lip color, lip glosses, massage gels.
Hectorite Gel is a hectorite gel soft, which is a dispersion of hectorite blended with triglyceride.


Hectorite Gel is very versatile and can be used to thicken oil-phase systems or to provide viscosity control.
Hectorite Gel also has shear-thinning viscosity and excellent suspension of pigments, actives, and controlled alignment of special-effect pigments.
Hectorite Gel is best to add the gel under agitation to a portion of the fat.



BENEFITS OF HECTORITE GEL:
*Hectorite Gel can be used hot or cold to thicken oil phase systems
*Hectorite Gel provides viscosity control
*Hectorite Gel enhances skin feel by masking greasy or tacky components
*Hectorite Gel provides softness and silkiness to the skin and color cosmetics
*Hectorite Gel possesses shear-thinning viscosity
Hectorite Gel is excellent suspension of pigments, actives and controlled alignment of special-effect pigments



COMPOSITION/INFORMATION ON INGREDIENTS:
Chemical Name CAS number Weight % Molecular Weight
Caprylic/capric triglyceride 73398-61-5 50 - 100% N/A
Stearalkonium hectorite 12691-60-0 5 - 20% N/A
Propylene carbonate 108-32-7 1 - 10% N/A



PROPERTIES OF HECTORITE GEL:
Hectorite Gel can be used hot or cold to thicken oil phase systems.
Hectorite Gel provides viscosity control, enhances skin feel by masking greasy or tacky components, and provides softness and silkiness to the skin and color cosmetics.

Hectorite Gel possesses shear-thinning viscosity, excellent suspension of pigments, actives and controlled alignment of special-effect pigments.
Hectorite Gel is best to add the gel under agitation to a portion of the fatty components.
Mix Hectorite Gel until the mixture becomes homogenous before adding any other ingredients.
Typical use level of Hectorite Gel is 2.5-10%.



KEY FEATURES OF HECTORITE GEL:
*Hectorite Gel provides shear-thinning viscosity and excellent suspension of pigments, actives, and controlled alignment of special-effect pigments
*Best to add the gel under agitation to a portion of the fatty components



FEATURES OF HECTORITE GEL:
*Thickens the formulation
*Enables very smooth application on surface
*Shear thinning effect on application
*Application of lip-sticks is very smooth
*Excellent Skin Feel
*Gel can be added at any convenient stage in the production cycle.



PROPERTY OF
Hectorite Gel can be used in cold processes, it is added to the fatty/oily phase, making sure it mixes perfectly with the less viscous lipids, it can be added at any stage of the production process.
Hectorite Gel gives a creamy and velvety sensation to the product and a slightly glossy and luminous finish.
Hectorite Gel improves the spreadability and silkiness of the final product on the skin as well as increasing its viscosity, suspending capacity and stability over time.



BENEFITS OF HECTORITE GEL:
- Hectorite Gel can be used hot or cold to thicken oil phase systems
- Hectorite Gel provides viscosity control
- Hectorite Gel enhances skin feel by masking greasy or tacky components
- Hectorite Gel provides softness and silkiness to the skin and color cosmetics
- Hectorite Gel possesses shear-thinning viscosity
- Excellent suspension of pigments, actives and controlled alignment of special-effect pigments



STORAGE SPACE OF HECTORITE GEL:
Hectorite Gel can be kept at space temperature However close the bottle snugly.
As well as secured from straight sunlight or warm, Hectorite Gel goes to the very least 2 years of age.



KEY PROPERTIES OF HECTORITE GEL:
Non-animal origin
Rheological control
• Predictable, reproducible and stable viscosity control
• Shear-thinning viscosity
• Excellent suspension of pigments and actives
• Controlled alignment of special-effect pigments
• Thermostable viscosity raises apparent melting point and ensures cost-efficient use of
UV filters
• Emulsion stabilization [w/o and o/w ]
Convenience
• Optimally pre-activated and dispersed organoclay
• Incorporates with medium-shear mixing
• Can be added at any convenient stage of manufacture
• Gives a high degree of formulating flexibility
• Provides highly reproducible results for multi-site production requirements
Acceptability
• Non-abrasive
• Provides smooth feel to skin
• Toxicologically safe ingredients



INCORPORATION OF HECTORITE GEL:
Hectorite Gel can be added at any convenient suitable stage during the manufacturing cycle.
Hectorite Gel additive is a very high viscosity, shear-thinning product.

To ensure good homogeneous mixing is achieved, care must be taken to overcome the large viscosity differential existing between the Hectorite Gel and the other lower
viscosity components.

Choice of mixing equipment and the configuration within the mixing vessels are critical factors in developing the optimum performance of the Hectorite Gel additives.
The use of medium- to high-shear mixing equipment is recommended.

Batch Processing:
• Single Phase Systems :
Always add the Hectorite Gel, under shear, to a portion of the organic component or solvent with which it is most compatible.
Mix until homogeneous before adding the other ingredients.

• Multi-Phase Systems e.g. emulsions:
Treat as the single phase but always ensure the Hectorite Gel additive is thoroughly mixed in before the emulsification stage.

• Continuous Processing:
The Hectorite Gel should be added to the oil phase at any convenient point that meets the above guidelines for batch processing.
In multi-manifold systems, a flowable pre-mix of the Hectorite Gel with a compatible oil or solvent should be made in a side pot.
Where only lower-shear mixing equipment is available, stir the Hectorite Gel alone and then slowly add the most compatible component by portions, always ensuring the mixture remains homogeneous at each stage.



COMPATIBILITY OF HECTORITE GEL:
Hectorite Gel additives can contribute greatly to a formulation’s stability by improving the compatibility of other ingredients.
Care should be taken to determine the compatibility of the Hectorite Gel additive with the oils, actives or surfactant ingredients within a formulation.
The wide range of grades available allows selection of the optimal carrier and organoclay for each system.



PHYSICAL and CHEMICAL PROPERTIES of HECTORITE GEL:
Color/Form: Tan paste
Viscosity: 1500 – 3200 (units, e.g., cP)
Ash Content: 7.6 - 8.2%
Infrared: To Match Standard
Microbial Content: Less than 100 cfu/g



FIRST AID MEASURES of HECTORITE GEL:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HECTORITE GEL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of HECTORITE GEL:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of HECTORITE GEL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HECTORITE GEL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of HECTORITE GEL:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


HECTORITE GEL
Hectorite gel is a naturally occurring 2 : 1 phyllosilicate clay of the smectite (montmorillonite) group and is a principal component of bentonite clay.
Hectorite gel occurs as an odorless, white to creamcolored, waxy, dull powder composed of aggregates of colloidalsized lath-shaped crystals.
Hectorite gel is used widely in pharmaceutical preparations as an absorbent, emulsifier, stabilizer, suspending agent, thickener, and viscosity-controlling agent.

CAS Number: 12173-47-6
Molecular Formula: H2LiMgNaO12Si4-2
Molecular Weight: 360.58645
EINECS Number: 235-340-0

Synonyms: HECTORITE, 12173-47-6, Hectorite (clay mineral), EINECS 235-340-0, UNII-08X4KI73EZ, 08X4KI73EZ, Hectorite ((Mg2.67Li0.33)Si4Na0.33(F0.5-1(OH)0-0.5)2O10), lithium, magnesium, sodium, 1,3,5,7-tetraoxido-2,4,6,8,9,10-hexaoxa-1,3,5,7-tetrasilatricyclo[5.1.1.13,5]decane, dihydroxide, Hectorite ((Mg2.67Li0.33)Si4Na0.33[F0.5-1(OH)0-0.5]2O10), HECTABRITE AW, HECTABRITE DP, HECTABRITE LT, ACCOFLOC HCX, SUMECTON HE, BENTONE CT, BENTONE HC, OPTIGEL SH, HECTORITE [MI], ASTRATONE 40, HECTORITE [INCI], HECTABRITE 200, KWLMIXQRALPRBC-UHFFFAOYSA-L, Q3129310, A MONTMORILLONITE MINERAL, A PRINCIPAL CONSTITUENT OF BENTONITE CLAY.

Hectorite gel is a component of other naturally occurring clays and hence may be suitable for use in similar pharmaceutical formulation applications as an adsorbent, oil-in-water emulsifying agent, suspending agent, or viscosity-increasing agent.
Hectorite gel is also available as a synthetic material. Hectorite is used to modify the thixotropic behavior of pharmaceutical dispersions and for stabilizing oil-inwater emulsion bases.
When combined with an appropriate cation, hectorite exhibits properties suitable for use as a contrast agent.

Hectorite gel is a very versatile dispersion of hectorite blended with triglyceride for adding viscosity of oil-phase systems.
Hectorite gel is a natural, soft, greasy, white clay mineral occurring in volcanic ash and tuff.
Can be used hot or cold to thicken oil phase systems.

Enhances skin feel by masking greasy or tacky components.
Provides softness and silkiness to the skin and color cosmetics.
Possesses shear-thinning viscosity.

Excellent suspension of pigments, actives and controlled alignment of special-effect pigments.
Hectorite gel, a gelling agent for the oil.
Suitable for use in makeup formulations or any kind of cosmetics with a mixture of essential oils Developed specifically to hold (suspend) pigment pigments in formulas for even distribution of pigments in all types of make-up.

Hectorite gel is a smectite clay mineral obtained from the hectorite mine in California, USA, which is the largest and the purest clay and with high purity Makes it whiter and smoother.
Compared to other types of clays that can act as a thickener for oils, such as Bentonite.
Hectorite gel has the ability to bind (suspension) pigments, pearl powders and other shimmering powders into the formula without precipitation and make the color spread completely.

Hectorite gel Soft is a specially prepared dispersion of a non-animal origin organically modified hectorite in Caprylic/Capric Triglyceride.
This grade is designed to impart rheological control and suspension to organic- and silicone-based cosmetics.
Hectorite gel is also particularly useful in emulsions and can be used in "cold process" systems.

It provides thermostable viscosity control of the emulsion's oil phase, improves application properties, enhances skin-feel by masking greasy or tacky components and imparts a pleasant residual silkiness to the skin.
Hectorite gel is an alternative to traditional polymer or cellulose-based thickeners for stabilizing emulsions.
Very versatile dispersion of hectorite blended with isododecane for adding viscosity of oil-phase systems.

Hectorite gel is a natural, soft, greasy, white clay mineral occurring in volcanic ash and tuff light tan colored (buff) thick gel.
Hectorite gel is a specially prepared dispersion of a non-animal origin organically modified hectorite in Caprylic/Capric Triglyceride.
This grade is designed to impart rheological control and suspension to organic- and silicone-based cosmetics.

Hectorite gel is also particularly useful in emulsions and can be used in "cold process" systems.
It provides thermostable viscosity control of the emulsion's oil phase, improves application properties, enhances skin-feel by masking greasy or tacky components and imparts a pleasant residual silkiness to the skin.
Hectorite gel is an alternative to traditional polymer or cellulose-based thickeners for stabilizing emulsions.

Hectorite gel is compliant with RSPO, Vegan, and ISO 16128 requirements.
Hectorite gel is a specially prepared dispersion of a non-animal origin organically modified hectorite in Caprylic/CapricTriglyceride.
This grade is designed to impart rheological control and suspension to organic-and silicone-based cosmetics.

Hectorite gel series presents a highly specialized portfolio of pre-dispersed gels to help the formulators achieve the right rheological properties for aqueous & non-aqueous formulations.
This range includes pre-dispersed & activated systems made from different types of cosmetic oils, esters & solvents, enabling excellent dispersibility of additives with minimum shearing.
Hectorite gels have very high viscosity & shear-thinning properties and are very easy to handle & use.

Hectorite gel by Elementis is a non-abrasive, non-animal origin rheological additive for cosmetics and toiletries.
It is a specially prepared dispersion of an organically modified hectorite in volatile silicone (pentamer).
Hectorite gel provides rheological control & suspension to organic- and silicone-based cosmetics and offers thermostable viscosity control of the emulsion's oil phase.

It improves application properties and enhances skin-feel while masking greasy or tacky components and imparting a smooth and residual silky feel.
Hectorite gel is suitable as an alternative to traditional polymer or cellulose-based thickeners for stabilizing emulsions.
Hectorite gel offers predictable, reproducible & stable viscosity control, shear-thinning viscosity along with excellent suspension of pigments & actives.

Also, provides controlled alignment of special-effect pigment, raises apparent melting point and ensures cost-efficient use of UV filters.
Hectorite gel can be used in cold process systems.
Hectorite gel is used in formulating antiperspirants, lip care, eye make-up, emulsions, facial make-up, creams & lotions, lip products and sun care products.

Hectorite gel is RSPO approved the shelf life of this grade is 2 years.
Hectorite gel is a type of gel that is primarily composed of hectorite, a clay mineral.
Hectorite gel is known for its ability to swell in water and form a stable gel-like consistency when dispersed in a liquid medium.

Hectorite gel is often used as a thickening agent in cosmetic and personal care products such as creams, lotions, and gels.
Hectorite gel helps to improve the viscosity and texture of formulations, giving them a smooth and luxurious feel.
In addition to thickening, hectorite gel can also act as a stabilizer, helping to prevent the separation of ingredients in emulsions and suspensions.

It enhances the stability of formulations and contributes to their overall quality and performance.
Hectorite gel can suspend solid particles or other ingredients within a liquid matrix, preventing them from settling to the bottom over time.
This property is particularly useful in formulations such as suspensions, paints, and coatings.

Hectorite gel can modify the rheological properties of a formulation, influencing its flow behavior, viscosity, and thixotropy.
Hectorite gel can help control the flow characteristics of products during application and improve their performance under various conditions.
Hectorite gel has absorbent properties that can help absorb excess oil and moisture from the skin, making it suitable for use in skincare products such as masks, cleansers, and mattifying formulations.

Hectorite gels can contain a wide range of minerals, including metals, non-metals, and rare earth elements.
Common metallic ores include iron ore (hematite, magnetite), copper ore (chalcopyrite, bornite), gold ore (native gold, gold-bearing quartz), and aluminum ore (bauxite). Non-metallic ores include limestone, gypsum, phosphate rock, and sulfur.
Hectorite gels are found in nature in various geological formations, including veins, lodes, deposits, and beds.

They may be located near the Earth's surface (as in the case of placer deposits) or deep underground (as in the case of underground mining).
The extraction of Hectorite gels involves mining, which can be done through surface mining or underground mining methods.
Surface mining methods include open-pit mining, quarrying, and strip mining, while underground mining methods include drift mining, shaft mining, and room and pillar mining.

The choice of mining method depends on factors such as the depth of the ore deposit, its size, and the economics of extraction.
Hectorite gels are mined, they undergo processing to extract the valuable minerals.
This may involve crushing, grinding, flotation, leaching, and smelting processes, depending on the nature of the ore and the desired end products.

Processing plants are often located near the mining sites to minimize transportation costs.
The extracted minerals from Hectorite gel are used in various industries and applications.
Metals such as iron, copper, aluminum, and gold are used in manufacturing, construction, electronics, and other sectors.

Hectorite gels are used in construction materials, fertilizers, chemicals, and other industrial processes.
Ore mining and processing can have significant environmental impacts, including habitat destruction, soil erosion, water pollution, and air pollution.
Mining operations often require large amounts of water and energy, and the disposal of mining waste (tailings) can pose environmental challenges if not managed properly.

The disposal and management of mining waste, known as tailings, is a significant environmental concern in the mining industry.
Hectorite gels contain residual metals, chemicals, and other contaminants that can pose risks to water quality and ecosystem health if not properly managed.
Hectorite gels storage facilities, engineered containment structures, and innovative tailings management technologies are used to minimize the environmental impact of tailings disposal.

As finite resources, Hectorite gels are subject to depletion over time, leading to concerns about long-term resource sustainability.
Sustainable mining practices aim to balance resource extraction with environmental protection and social responsibility, ensuring that mineral resources are managed responsibly for future generations.
This includes efforts to minimize waste generation, improve resource efficiency, and promote recycling and circular economy principles.

CAS DataBase Reference: 12173-47-6
FDA 21 CFR: 310.545
EWG's Food Scores: 1-2

Hectorite gel thickener, rheological agent and a great dispersant of solid particles in the form of a ready-made gel; for cosmetics based on trisiloxane, an alternative to products with cyclopentasiloxane
Detailed explanations on the chemistry and properties of natural Hectorite clay can be found in the leaflet “Chemistry and properties of Hectorite gel clay based rheology modifiers”.
In this second part, the technical benefits are shown based on some typica applications of this unique mineral.

Hectorite gel is a smectite clay mineral (sodium lithium magnesium silicate) that swells after immersion and dispersion in water.
Under the correct conditions it imparts shear-thinning flow and thixotropy, as well as controling sedimentation efficiently.
Hectorite gel is a naturally occuring, lightly-coloured mineral and can be found in very few locations globally, primarily in Hector, near Newberry Springs in California.

Hectorite gel is in a wet process refined to provide an additive of very high purity.
In its normal form Hectorite gel is hydrophilic and can either be used pure or combined with polymers or dispersants to give exactly the required flow properties to aqueous formulations.
Reaction with quaternary ammonium compounds converts the clay to a hydrophobic form that is used for solvent-borne systems – an organoclay.

Depending on the type of quaternary ammonium species used, products can be designed for all different polarities and chemistries of solvents.
All these products are commercially available under the registered BENTONE® name and are considered the industry bench-mark.
Hectorite gels are categorized based on their reserves and resources.

"Reserves" refer to known deposits of minerals that can be economically extracted with current technology and market conditions, while "resources" include both reserves and potentially recoverable deposits that may become economically viable with advances in technology or changes in market conditions.
The grade of an Hectorite gel refers to the concentration of the valuable minerals it contains.
Higher-grade Hectorite gels have a higher concentration of valuable minerals and are typically more economically viable to mine and process.

The quality of the Hectorite gel, including its purity and chemical composition, can also influence its suitability for specific applications and processing methods.
Hectorite gels contain valuable minerals as well as by-products or co-products that can be recovered during the extraction and processing process.
For example, copper ores may contain valuable metals such as gold, silver, and molybdenum as by-products.

Hectorite gels are minerals that are extracted alongside the primary metal and have economic value.
Hectorite gels are found in diverse geological formations around the world, and their distribution can vary widely by region.
Certain countries or regions may be rich in specific types of ores, leading to significant mining activities and economic development.

The distribution of Hectorite gels can influence global trade patterns and geopolitical dynamics.
The discovery of new Hectorite gel deposits often involves extensive exploration activities, including geological mapping, geochemical analysis, geophysical surveys, and drilling.
Exploration companies use advanced technologies and scientific methods to identify and evaluate potential ore deposits, which can involve significant investments of time and resources.

As global demand for minerals increases and concerns about resource depletion and environmental sustainability grow, there is growing interest in recycling and reclamation of metals from ores and industrial waste streams.
Hectorite gels from products at the end of their life cycle can reduce the need for primary ore extraction and minimize environmental impacts associated with mining.
The availability and pricing of Hectorite gels are influenced by market dynamics, including supply and demand trends, geopolitical factors, technological advancements, and regulatory policies.

Fluctuations in commodity prices can impact the profitability of mining operations and drive investments in exploration and development.
Various mining Hectorite gels are employed to extract ores from the Earth's crust, each suited to different geological conditions and deposit types.
These Hectorite gel range from conventional methods such as open-pit mining and underground mining to advanced technologies like in-situ leaching and block caving.

The choice of mining method depends on factors such as ore depth, deposit size, ore grade, and environmental considerations.
Mining operations can have significant environmental impacts, including habitat disruption, soil and water contamination, and landscape alteration.
Environmental remediation measures, such as land reclamation, water treatment, and biodiversity conservation, are often implemented to mitigate these impacts and restore affected ecosystems.

Hectorite gel mining can have both positive and negative social and economic impacts on local communities and regions.
While mining activities can create employment opportunities, stimulate economic growth, and contribute to infrastructure development, they can also lead to social conflicts, displacement of communities, and cultural disruption.
Responsible mining practices aim to maximize the benefits of mining while minimizing its adverse effects on communities and livelihoods.

Uses:
Hectorite gel is one of the principal constituents of bentonite clay.
Hectorite gel is used as a thickener and suspending agent in water-based systems in oil-in-water emulsions.
Hectorite gel can be used add to oil-phase of formulas; mix into low amounts of oils to overcome large viscosity differences.

Hectorite gel is best to add the gel under agitation to a portion of the fatty components.
Mix until the mixture becomes homogenous before adding any other ingredients.
Hectorite gel is used in the production of steel, which is essential for construction, infrastructure, machinery, transportation, and various industrial applications.

Utilized in electrical wiring, plumbing, electronics, telecommunications, and construction materials.
Hectorite gel is used to produce aluminum metal, which is widely used in transportation (e.g., automobiles, aircraft), construction, packaging, and consumer goods.
Valued for its rarity and aesthetic appeal, gold is used in jewelry, electronics, dentistry, and as a financial reserve.

Hectorite gel is used in jewelry, silverware, electronics, photography, mirrors, and medical instruments.
Hectorite gel is used in batteries, ammunition, radiation shielding, construction materials, and soldering.
Hectorite gel utilized in galvanizing steel, producing brass and bronze alloys, and in various industrial applications (e.g., rubber manufacturing, paints, pharmaceuticals).

Hectorite gel is used as a building material, in cement production, as a soil conditioner, in water treatment, and in various industrial processes.
Hectorite gel utilized in construction materials (e.g., drywall, plaster), agriculture (as a soil amendment), and industrial applications (e.g., cement, fertilizer).
Hectorite gel is used in fertilizer production to supply essential nutrients (phosphorus) for plant growth.

Hectorite gel is used in the production of sulfuric acid, fertilizers, chemicals, pharmaceuticals, and in various industrial processes.
Mined for its potassium content, which is essential for plant growth and used in fertilizers.
Hectorite gel is used in electronics (e.g., magnets, batteries), renewable energy technologies (e.g., wind turbines, electric vehicles), and defense applications.

Hectorite gel is used in drilling muds, foundry sands, cat litter, sealants, and as a binder in iron ore pelletization.
Hectorite gel is used in ceramics, paper production, paint, rubber, cosmetics, and pharmaceuticals.
Hectorite gel utilized in plastics, paper, ceramics, cosmetics, pharmaceuticals, and as a lubricant.

Diamonds, Rubies, Sapphires, Emeralds, and other precious and semi-precious gemstones: Hectorite gel is Used in jewelry, decorative items, and as investment assets.
Mined for its high carbon content, graphite is used in various applications such as lubricants (both solid and powdered), batteries (especially lithium-ion batteries), refractories, foundry facings, and as a component in pencils and other writing instruments.

Hectorite gelis primarily used in the production of stainless steel, which is highly resistant to corrosion and widely used in kitchen appliances, cutlery, cookware, surgical instruments, and construction materials.
Hectorite gels are also used in chrome plating, pigments (e.g., in paints and inks), and tanning leather.

Hectorite gel is valued for its high strength-to-weight ratio, corrosion resistance, and biocompatibility.
It is used in aerospace components, armor plating, medical implants, sports equipment, chemical processing equipment, and in pigments for paints, plastics, and paper.
Hectorite gelis primarily used as fuel in nuclear power plants to generate electricity.

Hectorite gel is also used in nuclear weapons, medical imaging (as radioactive tracers), and in certain industrial applications (e.g., as a dense metal for counterweights and radiation shielding).
Platinum Group Metals (Platinum, Palladium, Rhodium, Ruthenium, Iridium, Osmium): These metals are used in catalytic converters to reduce harmful emissions from vehicles, in jewelry and decorative items, in electronics (especially in contacts and electrodes), in chemical processing catalysts, and in medical devices (e.g., pacemakers).

Hectorite gel has one of the highest melting points of all metals and is used in the production of high-temperature alloys, cutting tools (e.g., drills, saws, and milling cutters), electrical contacts and filaments, armor-piercing ammunition, and radiation shielding.
Hectorite gel is used in various applications such as electrical switches, fluorescent lamps, dental fillings, thermometers, and in the production of chlorine and caustic soda.
However, its use is declining due to environmental and health concerns associated with mercury toxicity.

Hectorite gel is used as an alloying element in steel production to improve strength, toughness, and corrosion resistance.
It is also used in the manufacturing of specialized alloys for aerospace, automotive, and chemical processing applications, as well as in energy storage technologies like vanadium redox batteries.

Safety Profile:
Hectorite gel is a natural clay mineral that is not considered acutely toxic; therefore no toxicity values have been established.
However, hectorite may contain small amounts of crystalline silica in the form of quartz.

Dust can be irritating to the respiratory tract and eyes, and contact with this material may cause drying of the skin.
Chronic exposure to crystalline silica may have adverse effects on the respiratory system.
EU labeling states that the material is not classified as dangerous.

HEDP
Etidronic Acid; 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid; Hydroxyethylidene-1,1-diphosphonicacid(HEDP); 1-Hydroxyethylidenediphosphonic Acid; Hydroxyethylidene Diphosphonic acid(HEDP); 1-Hydroxy-1,1-Ethanediyl ester; Oxyethylidenediphosphonic Acid(OEDP); 1-Hydroxyethane-1,1-diphosphonic acid , Tetrasodium salt; 1-Hydroxyethylidene-1,1-diphosphonic acid, Tetrasodium salt; Sodium HEDP; HEDPS; 1-hydroxyethylidenedi(phosphonic acid), Tetrasodium salt; (Hydroxyethylidene) diphosphonic acid, Tetrasodium salt; CAS NO:2809-21-4
HEDP (1-Hydroxy Ethylidene-1,1-Diphosphonic Acid)
Etidronic Acid; 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid; Hydroxyethylidene-1,1-diphosphonicacid(HEDP); 1-Hydroxyethylidenediphosphonic Acid; Hydroxyethylidene Diphosphonic acid(HEDP); 1-Hydroxy-1,1-Ethanediyl ester; Oxyethylidenediphosphonic Acid(OEDP); 1-Hydroxyethane-1,1-diphosphonic acid , Tetrasodium salt; 1-Hydroxyethylidene-1,1-diphosphonic acid, Tetrasodium salt; Sodium HEDP; HEDPS; 1-hydroxyethylidenedi(phosphonic acid), Tetrasodium salt; (Hydroxyethylidene) diphosphonic acid, Tetrasodium salt; CAS NO:2809-21-4
HEDP (HIDROXY ETHYLIDENE DIPHOSPHONIC ACID)
Etidronic acid; etidronate; 1-Hydroxyethylidene-1,1-diphosphonic acid; Etidronsaeure; Acetodiphosphonic acid; Hydroxyethanediphosphonic acid; Oxyethylidenediphosphonic acid; HEDP; (Hydroxyethylidene) diphosphonic acid; 1-Hydroxyethane-1,1-diphosphonic acid; 1-Hydroxyethylidene-1,1-diphosphonic acid; 1-hydroxyethylidenedi(phosphonic acid) cas no:2809-21-4
HEDP 4NA
HEDP 4NA IUPAC Name (1-hydroxy-1-phosphonoethyl)phosphonic acid HEDP 4NA InChI InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9) HEDP 4NA InChI Key DBVJJBKOTRCVKF-UHFFFAOYSA-N HEDP 4NA Canonical SMILES CC(O)(P(=O)(O)O)P(=O)(O)O HEDP 4NA Molecular Formula C2H8O7P2 HEDP 4NA CAS 2809-21-4 HEDP 4NA Related CAS 14860-53-8 (tetra-potassium salt) HEDP 4NA Deprecated CAS 100511-44-2 HEDP 4NA European Community (EC) Number 220-552-8 HEDP 4NA NSC Number 227995 HEDP 4NA UNII M2F465ROXU HEDP 4NA DSSTox Substance ID DTXSID6023028 HEDP 4NA Physical Description Liquid HEDP 4NA Boiling Point 578.8 HEDP 4NA Melting Point 198-199 HEDP 4NA Solubility 3.35 M HEDP 4NA LogP -3.8 HEDP 4NA Drug Indication Etidronate is indicated to treat Paget's disease of bone, as well as the treatment and prevention of heterotropic ossification after total hip replacement of spinal cord injury. HEDP 4NA Metabolism/Metabolites Etidronic acid is not metabolized _in vivo_ HEDP 4NA Biological Half-Life The half life of etidronate is approximately 1-6 hours. HEDP 4NA Molecular Weight 206.03 g/mol HEDP 4NA XLogP3-AA -3.7 HEDP 4NA Hydrogen Bond Donor Count 5 HEDP 4NA Hydrogen Bond Acceptor Count 7 HEDP 4NA Rotatable Bond Count 2 HEDP 4NA Exact Mass 205.974527 g/mol HEDP 4NA Monoisotopic Mass 205.974527 g/mol HEDP 4NA Topological Polar Surface Area 135 Ų HEDP 4NA Heavy Atom Count 11 HEDP 4NA Formal Charge 0 HEDP 4NA Complexity 211 HEDP 4NA Isotope Atom Count 0 HEDP 4NA Defined Atom Stereocenter Count 0 HEDP 4NA Undefined Atom Stereocenter Count 0 HEDP 4NA Defined Bond Stereocenter Count 0 HEDP 4NA Undefined Bond Stereocenter Count 0 HEDP 4NA Covalently-Bonded Unit Count 1 HEDP 4NA Compound Is Canonicalized Yes Application Notes: HEDP 4NA.Na4 (similar to Dequest 2016) is the sodium salt of HEDP 4NA , it is a good scale inhibitor for calcium carbonate, it can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.The solid HEDP 4NA.Na4 is white powder, soluble in water, easily deliquescence, suitable for use in winter and freezing districts. It is a kind of organophorphonic acid scale and corrosion inhibitor, can form stable complex with Fe, Cu and Zn ions, it can dissolve the oxides on metal surface, it has good scale and corrosion inhibition effect under 250°C.Recommended Uses: HEDP 4NA.Na4 is widely used in circulating cool water system, medium and low pressure boiler, oil field water pipelines as scale and corrosion inhibitor in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.. In light woven industry, HEDP 4NA.Na4 is used as detergent for metal and nonmetal. In dyeing industry, HEDP 4NA.Na4 is used as peroxide stabilizer and dye-fixing agent; In non-cyanide electroplating, HEDP 4NA.Na4 is used as chelating agent.HEDP 4NA is the sodium salt of HEDP 4NA, HEDP 4NA is an good scale inhibitor for calcium carbonate, it can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.The solid HEDP 4NA is white powder, soluble in water, easily deliquescence, suitable for use in winter and freezing districts. It is a kind of organophorphonic acid scale and corrosion inhibitor, can form stable complex with Fe, Cu and Zn ions, it can dissolve the oxides on metal surface, it has good scale and corrosion inhibition effect under 250℃. HEDP 4NA is widely used in circulating cool water system, medium and low pressure boiler, oil field water pipelines as scale and corrosion inhibitor in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.. In light woven industry, HEDP 4NA is used as detergent for metal and nonmetal. In dyeing industry, HEDP 4NA is used as peroxide stabilizer and dye-fixing agent; In non-cyanide electroplating, HEDP 4NA Na4 is used as chelating agent. HEDP 4NA is even granule with excellent fluidity, low dust content, low hygroscopicity and easy handling properties. HEDP 4NA is a powerful chelating agent. As a household cleaning agent and industrial cleaner auxiliary, HEDP 4NA·Na4 can stabilize metal ions in water and enhance effect of decontamination under high pH washing condition. HEDP 4NA can be used in cosmetics and personal care to restrain rancidity and discoloration. HEDP 4NA can be used as slow-release scale corrosion inhibitor after being compressed into tablets with other auxiliaries. HEDP 4NA works as oxygen bleaching stabilizer in dyeing and paper making industry.Usage:The dosage of HEDP 4NA·Na4 is around 1.0-5.0% when used as chelating agent in cleaning industry. It works better when combined with polyacrylate sodium, copolymer of maleic and acrylic acid.Package and Storage:The packing of HEDP 4NA·Na4 granule is film lined kraft valve bag, with net weight 25kg/ bag, 1000kg/ tonnage bag, or as per customer’s request. Storage for one year in shady room and dry place.Safety Protection:HEDP 4NA·Na4 is alkaline, pay attention to labor protection during operation. Avoid contacting with eye and skin, once contacted, flush with water and then seek medical advice.HEDP 4NA Na4 is also called HEDP 4NA Tetrasodium Salt. It is the tetrasodium salt of HEDP 4NA acid.HEDP 4NA Na4 is an organic phosphonic acid salt. This product is a sodium salt of excellent performance in inhibiting the formation of calcium carbonate and calcium sulphate. It is also an excellent chelating agent. HEDP 4NA Na4 can form the stable complex with Fe, Cu and Zn ions.The solid HEDP 4NA Na4 is a white powder. It is soluble in water. This HEDP 4NA tetrasodium salt easily deliquescence. So it is suitable for use in winter and freezing districts. HEDP 4NA Na4 can dissolve the oxides on the metal surface. It has good scale and corrosion inhibition effect under 250℃.This tetrasodium of HEDP 4NA is used as a stabilizer in cosmetic-dye industry. It also prevents swelling problems of the packages. HEDP 4NA Na4 provides chlorine resistance in swimming pools and removes stains from the centre (usage level 1 – 15 ppm active substance).Britequest HEDP 4NA.xNa, .2Na and .4Na are the sodium salts of Britequest HEDP 4NA. Britequest HEDP 4NA.Na is harmless and thus easier to use than the harmful acid. In cold climates the additional advantage is that the Britequest HEDP 4NA.Na powders do not freeze, contrary to the acidic solutions Britequest HEDP 4NA. The powders are easily soluble in water and form stable complexes with Fe, Cu, Zn ions. Thus it avoids scale of these ions. The anti scaling and corrosion inhibtion are optimum up to 250oC, at low and high pH as Britequest HEDP 4NA.Nax are not easily hydrolyzed. Their Cl-stability is better than that of general phosphonates. The synergistic effect with other water treatment chemicals is proven.The ‘x’ in Britequest HEDP 4NA.Nax indicates that the sodium number in this salt is not fixed. We can fix it at 2, or 4, or leave it variable; x.They are used in detergents, industrial and municipality water treatment, as additives to cooling and heating water (low and medium pressure boilers) and water used in oil fields.Britequest DTPMP.Nax have the positive side effects of stabilizing other reactive additives, such as peroxides in detergents, dye-fixing in textiles and chelating in non-cyanide electro plating.We can also supply Britequest HEDP 4NA.Nax types as water solutions.1-Hydroxyethylidene-1,1-diphosphonic acid tetrasodium salt (HEDP 4NA) is a cost effective scale inhibitor used in various industrial applications such as industrial water treatment and detergents. It further shows good stability in presence of chlorine as well as corrosion inhibition properties in presence of zinc and other phosphates.HEDP 4NA CAS No - 2809-21-4 Synonyms - 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid, Hydroxyethylidene Diphosphonic Acid.HEDP 4NA or Hydroxyethylidene Diphosphonic Acid serves as an organo phosphonate compound having multifunctional properties such as deflocculation, sequestration, and super threshold inhibition as a single active ingredient. HEDP 4NA are available in salts of sodium compounds such as HEDP 4NA 2Na (Hydroxyethylidene Diphosphonic Acid - Disodium salt), HEDP 4NA 4Na (Hydroxyethylidene Diphosphonic Acid - Tetra sodium salt) etc.Application :HEDP 4NA Is Used in Low Pressure Boiler, Oil Field Water Pipelines as Scale And Corrosion Inhibition.HEDP 4NAis used as astrong chelating agent for metal ions like Ca, Mg & Fe.HEDP 4NA is used in Water Treatment process.HEDP 4NA is used in Textile Application.HEDP 4NA is used in Sugar Processing.HEDP 4NA is used Dyes& Pigments Manufacturing.HEDP 4NA is used in Soap & Detergents industry.HEDP 4NA Is Used in Electric Power, Chemical Industry, Metallurgy, Fertilizer and Other Industrial Cooling Water System.In Dyeing Industry, HEDP 4NAis Used as Peroxide Stabilizer and Dye-Fixing Agent.In Non-Cyanide Electroplating, HEDP 4NA Is Used as Chelating Agent.HEDP 4NAis Used in The Textile Industry, Used as Metal and Non-Metallic Cleaning Agent.In light woven industry, HEDP 4NA is Used as detergent for metal and nonmetal.1-Hydroxy-1,1-ethane-diphosphonic acid, 4Na Salt 3794-83-0 HEDP 4NA.HEDP 4NA, also known as etidronate, is a bisphosphonate used as a medication, detergent, water treatment, and cosmetic.It was patented in 1966 and approved for medical use in 1977.[1]Use Medical HEDP 4NA is a bisphosphonate used to strengthen bone, treat osteoporosis, and treat Paget's disease of bone.Bisphosphonates primarily reduce osteoclastic activity, which prevents bone resorption, and thus moves the bone resorption/formation equilibrium toward the formation side and hence makes bone stronger on the long run. Etidronate, unlike other bisphosphonates, also prevents bone calcification. For this reason, other bisphosphonates, such as alendronate, are preferred when fighting osteoporosis. To prevent bone resorption without affecting too much bone calcification, etidronate must be administered only for a short time once in a while, for example for two weeks every 3 months. When given on a continuous basis, say every day, etidronate will altogether prevent bone calcification. This effect may be useful and etidronate is in fact used this way to fight heterotopic ossification. But in the long run, if used on a continuous basis, it will cause osteomalacia.Chemical Main article: Corrosion inhibitor.HEDP is used as a retardant in concrete, scale and corrosion inhibition in circulating cool water system, oil field and low-pressure boilers in fields such as electric power, chemical industry, metallurgy, fertilizer, etc. In light woven industry, HEDP is used as detergent for metal and nonmetal. In dyeing industry, HEDP is used as peroxide stabilizer and dye-fixing agent; In non-cyanide electroplating, HEDP is used as chelating agent. The dosage of 1–10 mg/L is preferred as scale inhibitor, 10–50 mg/L as corrosion inhibitor, and 1000–2000 mg/L as detergent. Usually, HEDP is also used together with polycarboxylic acid (superplasticizer), in which it acts as reducing agent.Chelating agent and antioxidant.HEDP 4NA is a chelating agent and may be added to bind or, to some extent, counter the effects of substances, such as calcium, iron or other metal ions, which may be discharged as a component of grey wastewater and could conceivably contaminate groundwater supplies. As a phosphonate it has corrosion inhibiting properties on unalloyed steel. HEDP 4NA also acts to retard rancidification and oxidation of fatty acids.HEDP and its salts are added to detergents and other cleaning agents to prevent the effects of hard water. It is also used in peroxide bleaching to prevent degradation of peroxides by transition metals.HEDP 4NA is listed as an ingredient of several cosmetic formulations where it is used for suppressing radical formation, emulsion stabiliser and viscosity control. While HEDP 4NA has not been limited from inclusion in cosmetics and does have legitimate uses, it is recommended that, as with most cosmetic products (particularly soaps), the product should be thoroughly rinsed from the skin after use.HEDP 4NA is also included among swimming pool chemicals. It is used as a stain inhibitor to prevent metal ions coming out of solution and staining the sides of swimming pools. Overview Etidronic Acid is indicated for diseases such as Paget's disease, Heterotopic ossification and other writing. Detailed information on the part of the Etidronic product, side effects, product-related problems, questions, interactions and young children are as follows: source Etidronic Acid is used for the treatment, control, prevention & improvement of the following diseases, conditions and symptoms: Paget's disease Heterotopic ossification Further information: Uses Side effects The following is a list of possible effects that may occur from drugs that develop Etidronic Acid. This is not an exhaustive list. These side effects are likely to occur, but do not always occur. Although your side effects are rare, they can be very serious. Be sure to consult a doctor if you observe any of the web side effects, especially those that do not go away despite waiting. Diarrhea Nausea Baldness Arthritis Bone fracture Glossit Hypersensitivity reactions The softening of ossification Depression Hallucination Headache Gastritis Leg pain If you notice any side effects other than those listed below, consult your doctor for medical advice. You can also report side effects to your nearest health ministry official. Measures Before using this medicine, you should inform your doctor about currently available medicines, non-prescription oral medicines (oral, vitamins, herbal supplements, etc.), allergies, past illnesses and current health condition (word, pregnancy, upcoming surgery, etc.) inform. Certain health conditions can make you susceptible to the side effects of the medication. Get what is written on the quote or product you were directed to with your doctor. The dosage depends on your condition. If your condition persists or worsens, notify your doctor. The subject to be consulted is listed below. Monitoring with lytic lesions Monitor patients with Nephr kidney failure If you are using other drugs or at the same time using an over-the-counter medicine, with the effect of Etidronic Acid. This may cause the side effect not to work properly. Tell your doctor about all the encrypted medicines, vitamins, and herbal supplements so your doctor can block drug interactions. Etidronic Acid, ideas for interaction with the following drugs or products: Warfarin Etidronic Acid hypersensitivity is a contraindication. In addition, Etidronic Acid should not be used if you have the following conditions: Hypersensitivity Esophagus abnormalities Frequently Asked Questions Is this product safe to continue to drive or use machines? If you experience drowsiness, dizziness, hypotension (high blood pressure) or headache while using Etidronic Acid, your driving and / or construction equipment is safe. If the medicine used causes drowsiness, dizziness or lowers your blood secretions, you should not drive. In addition, pharmacists advise patients not to drink alcohol with the drug, as alcohol intensifies side effects such as drowsiness. Please observe this on your body when using Etidronic Acid. Always consult your doctor for advice specific to your body and health condition. Is this drug or product addictive or addictive? The other drug can be obviously addictive or abusive. Ministries categorize controlled addicts and non-addicts. For example, this classification is H and X in India and II and V in the USA. Please check the box to make sure the drug belongs to such a special classification. Finally, do not try to self-medicate and increase your body strength without the advice of a doctor. Can I quit this product right away? Am I out of use slowly? Some drugs should be tapered or their use should not be stopped suddenly to avoid withdrawal effects. Consult your doctor for advice and other medications specific to your body, health condition. Etidronic Acid and other important information Forgetting to take a dose If you forget to take a dose, it doesn't matter as soon as you use it. If your next dose is too close to your time, stick to the dose you missed and your dose schedule. Do not take extra doses to treat the missed dose. If you forget your doses, set an alarm or ask a family member to remind you. Please consult your doctor to write on your dosing schedule or to make up for the missed doses if you have recently forgotten too many doses.
HEDP·Na4
Hedp.Na4 is white powder, easily soluble in water, and hygroscopic.
Hedp.Na4 is a good inhibitor for calcium carbonate.


CAS Number: 3794-83-0
EC Number: 223-267-7
MDL Number:MFCD01729922
Molecular Formula: C2H8O7P2.4Na



SYNONYMS:
Tetrasodium 1-hydroxyethylidenediphosphonate, 1-Hydroxyethylidene-1, 1- Diphosphonic Acid Tetrasodium salt (Tetrasodium salt of HEDP (HEDP Na 4) , HEDP Na4, Ttrasodiquesel deHEDP, HEDPTetrasodyumtuz, tetrasodiumsal daHEDP, HEDP Chelant, Polycarboxylic antiscale, acid or Didronel, bisphosphonate or Etidronate, sodium etidronate, etidronate Tetrasodium, tetrasodium etidronate, Tetrasodium etidronate, HEDP 4Na, Tetrasodium (1-,hydroxyethylidene)bisphosphonate,
(1-hydroxyethylidene)-diphosphonicacitetrasodiumsalt, 1-Hydroxyethylidene-1,1-diphosphonicacid,tetrasodiumsalt, deflocen43, dequest2016, ethane-1-hydroxy-1,1-diphosphonicacid,tetrasodiumsalt, Phosphonicacid,(1-hydroxyethylidene)bis-,tetrasodiumsalt, sequion10na4, tarpinel4nl, HEDP.NA4, hydroxyethylidene diphosphonate, Sodium Salt of 1-Hydroxyethylene -1, 1,-Diphosphonic Acid HEDP.4Na, deflocen43, dequest2016, tarpinel4nl, turpinal4nl, sequion10na4, hedp tetrasodium salt, tetrasodiumetidronate, Phosphonic acid,P,P′-(1-hydroxyethylidene)bis-,sodium salt (1:4), Phosphonic acid,(1-hydroxyethylidene)di-,tetrasodium salt, Phosphonic acid,(1-hydroxyethylidene)bis-,tetrasodium salt, 1-Hydroxyethane-1,1-diphosphonic acid tetrasodium salt, Tetrasodium 1-hydroxy-1,1-ethanediphosphonate, Tetrasodium (1-hydroxyethylidene)bis[phosphonate], Dequest 2016, Sequion 10Na4, Tetrasodium etidronate, Tarpinel 4NL, Turpinal 4NL, Defloc EN 43, 1-Hydroxyethylidene-1,1-diphosphonic acid tetrasodium salt, SHEDN, DQ 2016, Tetrasodium (1-hydroxyethylidene)diphosphonate, Encap 81105, (Hydroxyethylidene)diphosphonic acid tetrasodium salt, Briquest ADPA 21SH, Chelest PH 214, Dequest 2016D, Tetrasodium HEDP, Feliox 115A tetrasodium salt, Tetrasodium hydroxyethylidene-1,1-diphosphonate, PH 214, Etidronic acid Tetrasodium salt, 104365-97-1, 146437-16-3, 863638-08-8, (1-Hydroxyethylidene)bis-phosphonic acid tetrasodium salt, 1-Hydroxyethylidene diphosphonic acid tetrasodium salt, tetrasodium (1-hydroxyethylidene) bisphosphonate, 1-Hydroxyethylidene-1,1-bis-(phosphonic acid) tetrasodium salt, Etidronate tetrasodium, Etidronic acid tetrasodium salt, 1-Hydroxyethane-1,1-diphosphonic acid tetrasodium salt, HEDP•Na4, Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:4), Tetrasodium (1-hydroxyethylidene)bisphosphonate, (1-Hydroxyethylidene)diphosphonic acid, tetrasodium salt, Defloc EN 43, Dequest 2016, Ethane-1-hydroxy-1,1-diphosphonic acid, tetrasodium salt,Phosphonic acid, (1-hydroxyethylidene )bis-, tetrasodium salt, Sequion 10Na4, Tarpinel 4NL, Tetrasodium etidronate,Turpinal 4NL, Phosphonic acid, (1-hydroxyethylidene)bis-, tetrasodium salt, Tetrasodium (1-hydroxyethane-1,1-diyl)bis(phosphonate), Phosphonic acid, (1-hydroxyethylidene)bis-, sodium salt (1:4), 3794-83-0, (1-hidroxietiliden)bisfosfonato de tetrasodio, (1-HYDROXYETHYLIDENE)BIS-, TETRASODIUM SALT, (1-hydroxyethylidene)bisphosphonate de tetrasodium, (1-Hydroxyethylidene)bisphosphonic acid tetrasodium salt, (1-Hydroxyethylidene)diphosphonate de tetrasodium, (Hydroxyethylidene)diphosphonic acid tetrasodium salt, 1-Hydroxyethane-1,1-diphosphonic acid tetrasodium salt, 1-Hydroxyethylidene-1,1-diphosphonic acid tetrasodium salt, 1-Hydroxyethylidene-1,1-diphosphonic acid, tetrasodium salt, Briquest ADPA 21 SH, Briquest ADPA 21SH, Chelest PH 214, Defloc EN 43, Dequest 2016, Dequest 2016D, Encap 81105, ETHANE-1,1-DIPHOSPHONATE, HYDROXY-, TETRASODIUM, Phosphonic acid, (1-hydroxyethylidene)di-, tetrasodium salt, Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:4), Sequion 10Na4, Tarpinel 4NL, Tetranatrium-(1-hydroxyethyliden)bisphosphonat, Tetrasodium (1-hydroxyethylidene)bis[phosphonate],tetrasodium (1-hydroxyethylidene)bisphosphonate, Tetrasodium (1-hydroxyethylidene)diphosphonate, Tetrasodium 1-hydroxy-1,1-ethanediphosphonate, Tetrasodium 1-hydroxyethylidene-1,1-diphosphonate, Tetrasodium etidronate, Tetrasodium HEDP, Turpinal 4NL, EINECS 223-267-7, Ethane-1-hydroxy-1,1-diphosphonic acid, tetrasodium salt, (1-Hydroxyethylidene)diphosphonic acid, tetrasodium salt, UNII-CZZ9T1T1X4, 104365-97-1, 146437-16-3, Na4HEDP, HEDPoNa4, deflocen43, turpinal4nl, dequest2016, Sodium HEDP, tetrasodiumetidronate, tetra sodium hydroxyethylidene diphosphonate, tetrasodium 1-hydroxyethylidene diphosphonate, Tetrasodium1-hydroxyethylidene-1,1-diphosphonate, Hydroxyethylene Diphosphonic Acid Tetrasodium Salt, ethane-1-hydroxy-1,1-diphosphonicacid, tetrasodiumsalt, (1-hydroxyethylidene)-diphosphonicacitetrasodiumsalt, tetrasodium (1-hydroxyethane-1,1-diyl)bis(phosphonate), ethane-1-hydroxy-1,1-diphosphonicacid, tetrasodiumsalt, (1-hydroxyethylidene)bis-phosphonicacitetrasodiumsalt, 1-Hydroxyethylidene Diphosphonic Acid Tetrasodium Salt, Phosphonicacid, (1-hydroxyethylidene)bis-, tetrasodiumsalt, 1-Hydroxyethylidene-1,1-diphosphonicacid, tetrasodiumsalt, (1-Hydroxyethylidene)bis-phosphonic acid tetrasodium salt, Phosphonicacid, (1-hydroxyethylidene)bis-, tetrasodiumsalt, Tetra sodium of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid, 1-Hydroxyethylidene-1,1-diphosphonicacid, tetrasodiumsalt, Sodium Salt of 1-Hydroxyethylene-1,1,-Diphosphonic Acid HEDP.4Na



Hedp.Na4 is a white powder, soluble in water, buoyant, suitable for use in winter.
Hedp.Na4 is white powder, easily soluble in water, and hygroscopic.
Hedp.Na4 is easy to transport and suitable for use in severe cold conditions.


Hedp.Na4 is an organic phosphonate scale and corrosion inhibitor.
Hedp.Na4 can form stable complexes with iron, copper, zinc and other metal ions, and can dissolve oxides on metal surfaces.
Hedp.Na4 still plays a good corrosion and scale inhibition role at 250℃.


Hedp.Na4 is a cost-effective scale inhibitor used in a variety of industrial applications such as industrial water treatment and detergents.
In addition, Hedp.Na4 shows good stability in the presence of chlorine, as well as corrosion inhibition properties in the presence of zinc and other phosphates.


Hedp.Na4 is a good inhibitor for calcium carbonate.
Hedp.Na4 is white powder, soluble in water, easily deliquescence, suitable for use in winter and freezing districts.
Hedp.Na4 is the sodium salt of HEDP.


Hedp.Na4 is white powder, soluble in water, easily deliquescence, suitable for use in winter and freezing districts.
Hedp.Na4 is a kind of organophorphonic acid scale and corrosion inhibitor, can form stable complex with Fe, Cu and Zn ions, it can dissolve the oxides on metal surface.


Hedp.Na4 has good scale and corrosion inhibition effect under 250℃.
Hedp.Na4 is a liquid corrosion inhibitor based on Tetrasodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid (HEDP).
As a member of the Salt of Organic Phosphates family, Hedp.Na4 offers outstanding scale and corrosion inhibition properties.


Hedp.Na4 ensures optimal performance, prolonging the lifespan and enhancing the efficiency of water systems while maintaining excellent water quality.
Hedp.Na4 is a white powder solid, easily soluble in water, non hygroscopic, convenient for transportation, and suitable for use under severe cold conditions.


Hedp.Na4 is an organic phosphonate scale and corrosion inhibitor.
Hedp.Na4 can form a stable complex with iron, copper, zinc and other metal ions and dissolve the oxides on the metal surface.
Hedp.Na4 still has good corrosion and scale inhibition at 250 ℃.


Hedp.Na4 is a solid form of Tetrasodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid (HEDP), classified as a Salt of Organic Phosphates with the CAS number 3794-83-0.
Hedp.Na4 is widely recognized for its exceptional scale and corrosion inhibition properties.


Hedp.Na4 is a liquid form of Tetrasodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid, belonging to the category of Salt of Organic Phosphates, offering excellent scale and corrosion inhibition properties for effective water treatment in various industrial applications.


Hedp.Na4 is a solid form of Tetrasodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid (HEDP), known for its exceptional scale and corrosion inhibition properties, making it an ideal choice for various industrial applications.
Hedp.Na4 is the sodium salt of HEDP.


Hedp.Na4 is white powder, soluble in water, easily deliquescence, suitable for use in winter and freezing districts.
Hedp.Na4 is a kind of organophorphonic acid scale and corrosion inhibitor, can form stable complex with Fe, Cu and Zn ions, it can dissolve the oxides on metal surface.


Hedp.Na4 has good scale and corrosion inhibition effect under 250ºC.
Hedp.Na4 is a sodium salt of HEDP, which is an excellent inhibitor of calcium carbonate scale.
Hedp.Na4 is a white powder solid, soluble in water, non-moisture absorption, easy to transport, suitable for use under severe cold conditions.


Hedp.Na4 is an organic phosphonate scale and corrosion inhibitor, which can form stable complexes with iron, copper, zinc and other metal ions, and can dissolve the oxides on the metal surface.
At 250 deg C, Hedp.Na4 is still play a good corrosion and scale inhibition.


Hedp.Na4 granule is the tera sodium salt of HEDP (Tetrasodium (1-hydroxyethylidene) biphosphonate).
Hedp.Na4 has excellent scale inhibition for calcium carbonate (CaCO3) and chlorine stability.
Hedp.Na4 has excellent free flowing and handling properties.


Hedp.Na4 is very low dust content(dust-free solid).
Hedp.Na4 finds use in Household detergents, I&I cleaners, etc.
Hedp.Na4 can be easily tableted.


Hedp.Na4 granular form is ideal for solid grade formulations.
The solid state of Hedp.Na4 is crystal powder, suitable for usage in winter and freezing districts.
Hedp.Na4 can be complexed with a variety of metal ions.


Hedp.Na4 has good heat resistance.
Hedp.Na4 still has a good effect at 200℃.
Hedp.Na4 is white powder, soluble in water, easily deliquescence, suitable for use in winter and freezing districts.


Hedp.Na4 is a kind of organophosphinic acid scale and corrosion inhibitor.
Hedp.Na4 can form stable complex with Fe, Cu and Zn ions, it can dissolve the oxides on metal surface, it has good scale and corrosion inhibition effect under 250℃.


Hedp.Na4 is the tetrasodium salt of hydroxy ethylidene diphosphonic acid.
Hedp.Na4 is a good scale inhibitor for calcium carbonate.
Hedp.Na4 is a white powder, soluble in water, easily deliquescence, suitable for use in winter and freezing districts.


Hedp.Na4 is a kind of organophorphonic acid scale and corrosion inhibitor.
Hedp.Na4 can form a stable complex with Fe, Cu, and Zn ions, dissolve the oxides on a metal surface, and has a good scale and corrosion inhibition effect under 250℃.


Hedp.Na4 is a white powder.
Hedp.Na4 can be soluble in water and easily deliquescence.
Hedp.Na4 is suitable for use in winter and freezing districts.


Hedp.Na4 is a kind of organophorphonic acid scale and corrosion inhibitor.
Hedp.Na4 is a kind of organophorphonic acid scale and corrosion inhibitor.
Hedp.Na4 can form a stable complex with Fe, Cu, and Zn ions.


Hedp.Na4 can dissolve the oxides on the metal surface.
Hedp.Na4 has a good scale and corrosion inhibition effect under 250℃.
Hedp.Na4 can dissolve in water and easily deliquescence.


Hedp.Na4 is suitable for use in winter and freezing districts.
Hedp.Na4 has a function as an acid scale and corrosion inhibitor.
Hedp.Na4 can form a stable complex with Fe, Cu and Zn ions.


Hedp.Na4 can dissolve the oxides on the metal surface.
Hedp.Na4 has a good scale and corrosion inhibition effect under 250°C.
Molecular Formula of Hedp.Na4 C2H4O7P2Na4



USES and APPLICATIONS of HEDP·Na4:
Hedp.Na4 can be used in low pressure boiler water system, circulating water system, industrial and municipal water treatment system and swimming pool.
Hedp.Na4 has a wide range of applications and is useful in very cold conditions.
Hedp.Na4 can be used to dissolve oxides on metal surfaces and has good scale and corrosion inhibition effect at 250C.


Hedp.Na4 is widely used in medium and low pressure cool water circulation, oil field water supply, as a corrosion inhibitor in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.
In the textile industry, Hedp.Na4 is used as a detergent for metals and non-metals.


In the dyeing industry, Hedp.Na4 is used as a peroxide stabilizer and as a dye fixer.
In non-cyanide HEDP plating, Na4 is used as a chelating agent.
Hedp.Na4 is the sodium salt of HEDP and is an excellent inhibitor of calcium carbonate scale.


Hedp.Na4 is mainly used for metal corrosion inhibition in low-pressure boiler water treatment, circulating water treatment, industrial and municipal clean water, and swimming pool sterilization.
Hedp.Na4 is widely used in industrial circulating cooling water, low-pressure boilers, oil field water injection and oil pipelines for scale and corrosion inhibition in electric power, chemical industry, metallurgy, fertilizer and other industries.


Hedp.Na4 can be used for metal and non-metal cleaning in the light textile industry.
Hedp.Na4 is used agents, peroxide stabilizers and color-fixing agents in the printing and dyeing industry, cyanide-free electroplating complexing agents, and daily chemical additives.


Hedp.Na4 is a kind of organophorphonic acid scale and corrosion inhibitor, can form stable complex with Fe, Cu and Zn ions, it can dissolve the oxides on metal surface, it has good scale and corrosion inhibition effect under 250℃.
Hedp.Na4 is widely used in circulating cool water system, medium and low pressure boiler, oil field water pipelines as scale and corrosion inhibitor in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.


In light woven industry, Hedp.Na4 is used as detergent for metal and nonmetal.
In dyeing industry, Hedp.Na4 is used as peroxide stabilizer and dye-fixing agent.
In non-cyanide electroplating, Hedp.Na4 is used as chelating agent.


Hedp.Na4 is an good scale inhibitor for calcium carbonate, it can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.
Hedp.Na4 is widely used in circulating cool water system, medium and low pressure boiler, oil field water pipelines as scale and corrosion inhibitor in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.


In light woven industry, Hedp.Na4 is used as detergent for metal and nonmetal.
In dyeing industry, Hedp.Na4 is used as peroxide stabilizer and dye-fixing agent.
In non-cyanide electroplating, Hedp.Na4 is used as chelating agent.


Hedp.Na4 is widely used in scale and corrosion inhibition of industrial circulating cooling water, low-pressure boiler, oilfield water injection and oil pipeline such as electric power, chemical industry, metallurgy and chemical fertilizer.
In light textile industry, Hedp.Na4 can be used as metal and non-metal cleaning agent, peroxide stabilizer and color fixing agent in printing and dyeing industry, cyanide free electroplating complexing agent and daily chemical additive.


Hedp.Na4 is widely utilized in industrial applications to effectively control scale formation and provide reliable protection against corrosion.
Hedp.Na4 is widely used in electric power, chemical industry, metallurgy, fertilizer and other industrial circulating cooling water and low pressure boiler, oil field water injection and oil pipeline of anti-scaling gentle erosion.


Hedp.Na4 is used in the textile industry, cleaning agent for metal and nonmetal peroxide stabilizer and fixing agent, printing and dyeing industry, without cyanide electroplating complexing agent, daily-use chemical additives.
Hedp.Na4 is widely used in electric power, chemical industry, metallurgy,fertilizer and other industrial circulating cooling water and low pressureboiler, oil field water injection and oil pipeline of anti-scaling gentle erosion.


Hedp.Na4 in the textile industry, cleaning agent for metal and nonmetalperoxide stabilizer and fixing agent, printing and dyeing industry, withoutcyanide electroplating complexing agent, daily-use chemical additives.
Hedp.Na4 is extensively used in various industrial applications, effectively controlling scale formation and providing reliable protection against corrosion.


Its solid form ensures convenient handling and storage, making Hedp.Na4 a preferred choice for efficient water treatment and system maintenance.
Hedp.Na4 is an good scale inhibitor for calcium carbonate, it can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.


Hedp.Na4 is widely used in circulating cool water system, medium and low pressure boiler, oil field water pipelines as scale and corrosion inhibitor.
Hedp.Na4 is used as detergent for metal and nonmetal.


In dyeing industry, Tetra Sodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid is used as peroxide stabilizer and dye-fixing agent; In non-cyanide electroplating, Tetra Sodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid is used as chelating agent.


Hedp.Na4 is an good scale inhibitor for calcium carbonate, it can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.
Hedp.Na4 is widely used in circulating cool water system, medium and low pressure boiler, oil field water pipescale and corrosion inhibitor.


Hedp.Na4 is widely used in circulating cool water system, medium and low pressure boiler, oil field water pipelines as scale and corrosion inhibitor in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.
In light woven industry, Hedp.Na4 is used as detergent for metal and nonmetal.


In dyeing industry, Hedp.Na4 is used as peroxide stabilizer and dye-fixing agent.
In non-cyanide electroplating, Hedp.Na4 is used as chelating agent.
Hedp.Na4 is an good scale inhibitor for calcium carbonate, it can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.


Hedp.Na4 is widely used as scale and corrosion inhibitor in circulating water system, medium and low pressure boiler, oil field water pipelines,Household and I&I (industrial & institutional) cleaners, detergents.
In light woven industry, Hedp.Na4 is used as detergent for metal and nonmetal.


In dyeing industry, Hedp.Na4 is used as peroxide stabilizer and dye-fixing agent.
In non-cyanide electroplating, Hedp.Na4 is used as chelating agent.
Hedp.Na4 is an organophosphoric acid corrosion inhibitor.


Hedp.Na4 has good antiscale and visible threshold effects.
When built together with other water treatment chemicals, Hedp.Na4 shows good synergistic effects.
Because of its high purity, Hedp.Na4 can be used as cleaning agent in electronic fields and as additives in daily chemicals.


Hedp.Na4 is mainly used for metal corrosion inhibition of low-pressure boiler water treatment, circulating water treatment, industrial municipal cleaning water and swimming pool sterilization.
Hedp.Na4 is widely used in electric power, chemical industry, metallurgy, chemical


Hedp.Na4 can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.
Hedp.Na4 is widely used in circulating cool water system, medium and low pressure boiler, oil field water pipelines as scale and corrosion inhibitor in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.


In light woven industry, Hedp.Na4 is used as detergent for metal and nonmetal.
In dyeing industry, Hedp.Na4 is used as peroxide stabilizer and dye-fixing agent.
In non-cyanide electroplating, Hedp.Na4 is used as chelating agent.


Hedp.Na4 can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming.
Hedp.Na4 is used as scale inhibitor in cooling water and boiler water treatment.
Hedp.Na4 can also be used as corrosion inhibitor, cyanide-free plating additive.


Hedp.Na4 is widely used in circulating cool water system ,medium and low pressure boiler , oil field water pipelines as scale and corrosion inhibitor in fields such as electric power ,chemical industry , metallurgy , fertilizer , etc .
Hedp.Na4 can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.


Hedp.Na4 is widely used in circulating cool water system ,medium and low pressure boiler , oil field water pipelines as scale and corrosion inhibitor in fields such as electric power ,chemical industry , metallurgy , fertilizer , etc .
In light woven industry , Hedp.Na4 is used as detergent for metal and nonmetal .


In dyeing industry , Hedp.Na4 is used as peroxide stabilizer and dye-fixing agent.
In non-cyanide electroplating , Hedp.Na4 is used as chelating agent .
Hedp.Na4 is the tetrasodium salt of HEDP.


Hedp.Na4 is a good scale inhibitor for calcium carbonate.
Hedp.Na4 can be used in a low-pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.
Hedp.Na4 is widely used in circulating cool water systems, medium and low-pressure boilers, and oil field water pipelines.


In addition, as the scale and corrosion inhibitor, Hedp.Na4 is used in fields such as electric power, the chemical industry, metallurgy, fertilizer, etc.
In the woven industry, Hedp.Na4 is used as a detergent for metal and nonmetal.
Hedp.Na4 is used as a peroxide stabilizer and dye-fixing agent in the dyeing industry.


In non-cyanide electroplating, Hedp.Na4 is used as a chelating agent.
Hedp.Na4 is widely used in circulating cool water systems, medium and low-pressure boilers, and oil field water pipelines as a scale and corrosion inhibitor in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.


In the light woven industry, Hedp.Na4 is used as a detergent for metal and nonmetal.
In the dyeing industry, Hedp.Na4 is used as a peroxide stabilizer and dye-fixing agent; In non-cyanide electroplating, HEDP tetrasodium is used as a chelating agent.
Hedp.Na4 can be used in low-pressure boiler water systems, circulating water systems, industrial and municipal cleaning water systems, and swimming pools.



PROPERTIES OF HEDP·Na4:
Hedp.Na4 is the sodium salt of HEDP, HEDP•Na4 is an good scale inhibitor for calcium carbonate, it can be used in low pressure boiler water system, circulating water system, industrial and municipal cleaning water system and swimming pool.
Hedp.Na4 is the tetrasodium salt of HEDP.
Hedp.Na4 is a good scale inhibitor for calcium carbonate.
Therefore, Hedp.Na4 can be used in a low-pressure boiler water system, circulating water system, industrial and municipal cleaning water system, and swimming pool.



PROPERTY OF HEDP·Na4:
Hedp.Na4 can be used in low pressure boiler water system , circulating water system, industrial and municipal cleaning water system and swimming pool.
The solid HEDP·Na4 is white powder, soluble in water, easily deliquescence, and suitable for use in winter and freezing districts.
Hedp.Na4 is a kind of organophosphonic acid scale and corrosion inhibitor.
Hedp.Na4 can form stable complex with Fe ,Cu and Zn ions ,it can dissolve the oxides on metal surface.
Hedp.Na4 has good scale and corrosion inhibition effect under 250℃ .



PHYSICAL and CHEMICAL PROPERTIES of HEDP·Na4:
Appearance: White powder, Colorless to yellowish transparent liquid
Active content (HEDP)%: 56.0 min 20.3-21.7
Active content (HEDP•Na4)%: 79.9 min 29.0-31.0
Total phosphoric acid (as PO43-) %: 52.0 min, 18.4-20.4
Fe,mg/L: 35.0 max, 20.0 max
Moisture,%: 15 max --
Density (20℃)g/cm3: -- 1.26-1.36
PH: 11.0-12.0 (1%water solution) 10.0-12.0 (as it)
CAS No.3794-83-0
MDL Number:MFCD01729922
Molecular Formula:C2H9NaO7P2
Density: 2.074[at 20℃]
vapor pressure: 0 Pa at 25℃
solubility: Aqueous Acid (Slightly), Water (Sparingly)

pka: 2.18[at 20 ℃]
form: Solid
color: White to Off-White
Water Solubility: 774g/L at 20℃
Stability: Hygroscopic
LogP: -3 at 23℃
CAS DataBase Reference: 3794-83-0(CAS DataBase Reference)
FDA UNII: CZZ9T1T1X4
EPA Substance Registry System: Phosphonic acid, (1-hydroxyethylidene)bis-, tetrasodium salt (3794-83-0)
PSA: 166.23000
XLogP3: 0.76060
Appearance: Liquid
Melting Point: 198-199ºC
Boiling Point: 578.8ºC at 760mmHg
Flash Point: 303.8ºC
CAS No.: 3794-83-0

Appearance: white solid and powder
Active content (as HEDP): ≥ 60.0%
Active content (as HEDP•Na4): ≥ 85%
Total phosphoric acid (as PO4): ≥ 52.0%
Iron (as Fe), ppm: ≤ 25 ppm
Moisture: ≤ 10%
PH(1% water solution): 10.5 ~ 12.0
InChIKeys: InChIKey=ZUNAHCVPCWCNPM-UHFFFAOYSA-N
Molecular Weight: 293.96
Exact Mass: 293.902313
EC Number: 223-267-7
UNII: CZZ9T1T1X4
DSSTox ID: DTXSID8027953|DTXSID7029663|DTXSID1029671
Categories: Phosphines
CAS NO:3794-83-0Molecular Formula: C2H4O7P2*4Na
Molecular Weight: 293.96

EINECS: 223-267-7
Product Categories: Phosphonate antiscalant
Mol File: 3794-83-0.mol
Melting Point: N/A
Boiling Point: 578.8 °C at 760 mmHg
Flash Point: 303.8 °C
Appearance: Brown viscous liquid
Density: 2.074[at 20℃]
Vapor Pressure: 0Pa at 25℃
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/APKA: 2.18[at 20 ℃]
Water Solubility: 774g/L at 20℃

CAS DataBase Reference: (1-Hydroxyethylidene)bis-phosphonic acid tetrasodium salt(CAS DataBase Reference)
NIST Chemistry Reference: (1-Hydroxyethylidene)bis-phosphonic acid tetrasodium salt(3794-83-0)
EPA Substance Registry System: (1-Hydroxyethylidene)bis-phosphonic acid tetrasodium salt(3794-83-0)
Density : 2.074[at 20℃]
vapor pressure: 0 Pa at 25℃
solubility: Aqueous Acid (Slightly), Water (Sparingly)
pka: 2.18[at 20 ℃]
form: Solid
color: White to Off-White
Water Solubility: 774g/L at 20℃
Stability: Hygroscopic
LogP: -3 at 23℃

CAS DataBase Reference :3794-83-0(CAS DataBase Reference)
EPA Substance Registry System: Phosphonic acid, (1-hydroxyethylidene)bis-, tetrasodium salt (3794-83-0)
CAS: 3794-83-0
EINECS: 223-267-7
InChI: InChI=1/C2H8O7P2.4Na/c1-2(3,10(4,5)6)11(7,8)9;;;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;;;/q;4*+1
Molecular Formula: C2H9NaO7P2
Molar Mass: 230.02 g/mol
Density: 2.074 g/cm3 at 20°C
Water Solubility: 774 g/L at 20°C
Vapor Pressure: 0 Pa at 25°C
Appearance: Crystalline powder
pKa: 2.18 at 20°C
Storage Condition: Room Temperature
Sensitive: Easily absorbs moisture



FIRST AID MEASURES of HEDP·Na4:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water.
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEDP·Na4:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEDP·Na4:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEDP·Na4:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEDP·Na4:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Recommended storage temperature see product label.



STABILITY and REACTIVITY of HEDP·Na4:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
no information available

HEDYOTIS DIFFUSA EXTRACT

Hedyotis Diffusa Extract, derived from the Hedyotis diffusa plant, is renowned for its anti-inflammatory, anti-cancer, and detoxifying properties.
Hedyotis Diffusa Extract is widely recognized for its ability to support immune health, reduce inflammation, and promote detoxification, making it a valuable ingredient in traditional medicine and wellness formulations.
This versatile extract offers both therapeutic and wellness benefits, helping to maintain immune function, detoxify the body, and reduce inflammation.

CAS Number: 84775-41-0
EC Number: 283-621-0

Synonyms: Hedyotis Diffusa Extract, Oldenlandia diffusa Extract, Hedyotis Herbal Extract, Hedyotis Phytocomplex, Hedyotis Bioactive Extract, Oldenlandia Herbal Extract, Oldenlandia Bioactive Extract, Hedyotis diffusa Active



APPLICATIONS


Hedyotis Diffusa Extract is extensively used in immune-boosting supplements, helping to enhance immune function and overall health.
Hedyotis Diffusa Extract is favored in the creation of detoxification products, supporting the removal of toxins and promoting liver health.
Hedyotis Diffusa Extract is utilized in the development of anti-inflammatory supplements, offering natural relief from inflammation and supporting overall wellness.

Hedyotis Diffusa Extract is widely used in the formulation of herbal remedies for cancer support, helping to inhibit the growth of cancer cells and promote healing.
Hedyotis Diffusa Extract is employed in traditional Chinese medicine formulations, where it supports immune health and promotes detoxification.
Hedyotis Diffusa Extract is essential in the creation of holistic wellness products designed to reduce inflammation and support the immune system.

Hedyotis Diffusa Extract is utilized in the production of natural remedies for detoxification, supporting liver function and promoting overall detox.
Hedyotis Diffusa Extract is a key ingredient in traditional herbal teas, offering benefits for immune support, detoxification, and reducing inflammation.
Hedyotis Diffusa Extract is used in the creation of cancer-support supplements, where it helps to inhibit the spread of abnormal cells.

Hedyotis Diffusa Extract is applied in the formulation of inflammation-reducing supplements, providing natural relief from chronic inflammation and promoting healing.
Hedyotis Diffusa Extract is employed in the production of wellness beverages, offering detoxifying and immune-boosting benefits for overall health.
Hedyotis Diffusa Extract is used in the development of holistic detox teas, helping to cleanse the body and reduce the buildup of harmful toxins.

Hedyotis Diffusa Extract is widely utilized in immune-boosting products, offering natural support for immune function and reducing the risk of illness.
Hedyotis Diffusa Extract is a key component in the creation of liver detox supplements, providing benefits for improving liver health and promoting detoxification.
Hedyotis Diffusa Extract is used in the production of inflammation-reducing teas, providing relief from inflammation and supporting overall immune health.

Hedyotis Diffusa Extract is employed in traditional herbal medicine products, where it supports immune function and detoxification processes.
Hedyotis Diffusa Extract is applied in the development of cancer-support supplements, providing natural aid in reducing the proliferation of cancer cells.
Hedyotis Diffusa Extract is utilized in the creation of antioxidant-rich beverages, supporting the body's defense mechanisms and reducing oxidative stress.

Hedyotis Diffusa Extract is found in the formulation of holistic detoxification products, providing natural support for cleansing the body and promoting immune health.
Hedyotis Diffusa Extract is used in the production of wellness capsules, offering natural detoxifying and immune-boosting benefits.
Hedyotis Diffusa Extract is a key ingredient in inflammation-reducing supplements, offering natural support for chronic inflammation and immune regulation.



DESCRIPTION


Hedyotis Diffusa Extract, derived from the Hedyotis diffusa plant, is renowned for its anti-inflammatory, anti-cancer, and detoxifying properties.
Hedyotis Diffusa Extract is widely recognized for its ability to support immune health, reduce inflammation, and promote detoxification, making it a valuable ingredient in traditional medicine and wellness formulations.

Hedyotis Diffusa Extract offers additional benefits such as promoting liver health, aiding in the reduction of tumor growth, and supporting the body's natural detoxification processes.
Hedyotis Diffusa Extract is often incorporated into formulations designed to promote immune function, reduce chronic inflammation, and detoxify the body from harmful substances.
Hedyotis Diffusa Extract is recognized for its ability to enhance overall health by providing natural support for the immune system and aiding in detoxification.

Hedyotis Diffusa Extract is commonly used in both traditional and modern wellness formulations, providing a reliable solution for maintaining immune health and reducing inflammation.
Hedyotis Diffusa Extract is valued for its ability to support the body's natural healing processes, making it a key ingredient in products that aim to improve immune function and promote detoxification.
Hedyotis Diffusa Extract is a versatile ingredient that can be used in a variety of products, including supplements, teas, capsules, and detox beverages.

Hedyotis Diffusa Extract is an ideal choice for products targeting immune support, inflammation reduction, and detoxification, providing natural and effective care for these wellness concerns.
Hedyotis Diffusa Extract is known for its compatibility with other immune-boosting and detoxifying ingredients, allowing it to be easily integrated into multi-functional formulations.
Hedyotis Diffusa Extract is often chosen for formulations requiring a balance between immune support, inflammation reduction, and detoxification, ensuring comprehensive wellness benefits.

Hedyotis Diffusa Extract enhances the overall effectiveness of wellness products by providing natural support for immune health, detoxification, and inflammation reduction.
Hedyotis Diffusa Extract is a reliable ingredient for creating products that offer a pleasant user experience, with noticeable improvements in detoxification, immune function, and inflammation levels.
Hedyotis Diffusa Extract is an essential component in innovative wellness products that stand out in the market for their performance, safety, and ability to support immune health and detoxification.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Hedyotis Diffusa Extract (Hedyotis diffusa Extract)
Molecular Structure:
Appearance: Brown to yellow powder or liquid extract
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If Hedyotis Diffusa Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Hedyotis Diffusa Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Hedyotis Diffusa Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Hedyotis Diffusa Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Hedyotis Diffusa Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.


HEMA
2-HEMA; HEMA, N° CAS : 868-77-9. Nom INCI : HEMA. Nom chimique : 2-Hydroxyethyl Methacrylate. N° EINECS/ELINCS : 212-782-2. Ses fonctions (INCI): Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Noms français : 2-(METHACRYLOYOXY)ETHANOL; 2-HYDROXYETHYL 2-METHYL-2-PROPENOATE; 2-HYDROXYETHYL ESTER, METHACRYLIC ACID; 2-Hydroxyethyl methacrylate; 2-PROPENOIC ACID, 2-METHYL-, 2-HYDROXYETHYL ESTER; HYDROXY-2 ETHYL METHACRYLATE; METHACRYLIC ACID, 2-HYDROXYETHYL ESTER; Méthacrylate d'hydroxy-2 éthyle; Méthacrylate d'hydroxyéthyle. Noms anglais : BETA-HYDROXYETHYL METHACRYLATE; ETHYLENE GLYCOL METHACRYLATE; ETHYLENE GLYCOL MONOMETHACRYLATE; ETHYLENE GLYCOL, MONOMETHACRYLATE; Hydroxyethyl methacrylate; MONOMETHACRYLIC ETHER OF ETHYLENE GLYCOL. Ce produit peut être inhibé avec de l'éther monométhylique de l'hydroquinone. Utilisation et sources d'émission Fabrication de polymères, fabrication de résines. (Hydroxyethyl)methacrylate [Wiki] 1,2-Ethanediol mono(2-methylpropenoate) 212-782-2 [EINECS] 2-Hydroxyethyl methacrylate [ACD/IUPAC Name] 2-Hydroxyethylmethacrylat [German] [ACD/IUPAC Name] 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester [ACD/Index Name] 868-77-9 [RN] Ethylene glycol methacrylate Glycol methacrylate Glycol monomethacrylate HEMA hydroxyethyl methacrylate Méthacrylate de 2-hydroxyéthyle [French] [ACD/IUPAC Name] MFCD00002863 [MDL number] β-Hydroxyethyl methacrylate [868-77-9] 1,2-Ethanediol mono(2-methyl)-2-propenoate 1,2-Ethanediol, mono(2-methyl)-2-propenyl 2-(Methacryloyloxy)ethanol 2-HYDROXY ETHYL METHACRYLATE 2-Hydroxyethyl 2-methylacrylate 2-hydroxyethyl 2-methylprop-2-enoate 2-Hydroxyethyl methacrylate (stabilised with hydroquinone monomethyl ether) 2-hydroxyethyl methacrylate 97% 2-hydroxyethyl methacrylate, 97%, stabilized 2-Hydroxyethyl methacrylate|2-(Methacryloyloxy)ethanol 2-hydroxyethylmethacrylate 2-Methyl-2-propenoic acid 2-hydroxyethyl ester 2-Methyl-2-propenoic acid, 2-hydroxyethyl ester 2-methylacrylic acid 2-hydroxyethyl ester 2-methylprop-2-enoic acid 2-hydroxyethyl ester 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, homopolymer 4-02-00-01530 [Beilstein] 4-02-00-01530 (Beilstein Handbook Reference) [Beilstein] 98%, stabilized with MEHQ Acryester HISS Bisomer HEMA EINECS 212-782-2 ethane-1,2-diol; 2-methyl-2-propenoic acid ETHYLENE GLYCOL MONOMETHACRYLATE Ethylene glycol, monomethacrylate GMA β-hydroxyethyl methacrylate Methacrylic acid 2-hydroxyethyl ester Methacrylic acid, 2-hydroxyethyl ester Monomer MG-1 β-Hydroxyethyl methacrylate. 2-(Methacryloyloxy)ethanol 2-hydroxyethyl methacrylate 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester Ethylene glycol methacrylate Ethylene glycol, monomethacrylate Glycol methacrylate Glycol monomethacrylate Hydroxyethyl methacrylate Methacrylic acid, 2-hydroxyethyl ester methacrylic acid, monoester with ethyleneglycol Mhoromer Monomer MG-1 Monomethacrylic ether of ethylene glycol Translated names (2-hydroxyetyl)-metakrylát (sk) 2-hidroksietil metakrilat (sl) 2-hidroksietil-metakrilat (hr) 2-hidroksietilmetakrilatas (lt) 2-hidroksietilmetakrilāts (lv) 2-hidroxietil metacrilat (ro) 2-hidroxietil-2-metakrilát (hu) 2-Hydroksietyylimetakrylaatti (fi) 2-hydroksyetylmetakrylat (no) 2-hydroxietylmetakrylat (sv) 2-hydroxyethyl-methakrylát (cs) 2-hydroxyethylmethacrylaat (nl) 2-hydroxyethylmethacrylat (da) 2-hüdroksüetüülmetakrülaat (et) 2-idrossietile metacrilato (it) 2-хидроксиетил метакрилат (bg) ester 2-hydroksyetylowy kwasu metakrylowego (pl) metacrilato de 2-hidroxietilo (es) metakrylan 2-hydroksyetylu (pl) méthacrylate de 2-hydroxyéthyle (fr) μεθακρυλικός 2-υδροξυαιθυλεστέρας (el) -hydroxyethyl methacrylate 2-hydroxethyl methacrylate 2-hydroxyethl methacrylate 2-Hydroxyethyl 2-methylacrylate 2-Hydroxyethyl 2-methylprop-2-enoate 2-Hydroxyethyl Methacrylate (stabilized with MEHQ) 2-hydroxyethyl-propenoicacid 2-Methyl-2-hydroxyethylester, -2-propenoic acid HEMA 2-HEMA 2-Hydroxyethyl ester, methacrylic acid 2-Hydroxyethyl-2-methyl-2-propenoate 2-Methyl-2-propenoic acid-2-hydroxyethyl ester 2-Methyl-acrylic acid 2-hydroxy-ethyl ester beta-Hydroxyethyl methacrylate CHINT: Methacrylic (EG)E Ethylene glycol monomethacrylate metacrilato de 2-hidroxietilo (Spanish) Methacrylate de 2-hydroxyethyle (French) Methacrylate, 2-hydroxyethyl Methacrylic acid-(2-hydroxy-ethyl ester) Methacrylsäure-(2-hydroxyethyl)-ester (German) (SWISS) Methacrylsäure-2-hydroxyethylester (german) Methylpropenoic acid, hydroxyethyl ester ROCRYL(TM) 400 (HEMA-LA)
HEMPSEED
cannabis sativa seed; seeds of cannabis sativa l., cannabaceae ; cannabis indica seed; cannabis sativa var. indica seed; hemp seed; hulled hemp seed cas no: 89958-21-4
HEPTANOIC ACID
Heptanoic acid is used in the preparation of esters, such as ethyl enanthate, which are used in fragrances and as artificial flavors.
Heptanoic acid is involved in the esterification of steroids and used in the preparation of active pharmaceutical ingredients such as trenbolone enanthate, testosterone enanthate, drostanolone enanthate, and methenolone enanthate.
Heptanoic acid's ester derivatives are used in the fragrance and flavor industries as well as cosmetics and industrial lubricants in aviation, refrigeration, and automobiles.

CAS number: 111-14-8
EC number: 203-838-7
Chemical formula: CH₃(CH₂)₅COOH
Molar Mass: 130.19 g/mol

Synonyms: HEPTANOIC ACID, 111-14-8, Enanthic acid, n-Heptanoic acid, Oenanthic acid, Enanthylic acid, Heptoic acid, n-Heptylic acid, n-Heptoic acid, Heptylic acid, Oenanthylic acid, 1-Hexanecarboxylic acid, Hexacid C-7, FEMA No. 3348, Heptanoic acid (natural), NSC 2192, CCRIS 6042, enanthoic acid, Hepthlic acid, HSDB 5546, UNII-THE3YNP39D, THE3YNP39D, EINECS 203-838-7, MFCD00004426, Technetium Medronate, BRN 1744723, DTXSID2021600, CHEBI:45571, AI3-02073, Artec ultra conditioning teat dip, HEPTANOIC AICD-, NSC-2192, DTXCID301600, NSC2192, EC 203-838-7, 4-02-00-00958 (Beilstein Handbook Reference), C7:0, sec-Heptanoic acid, 101488-09-9, ENANTHIC ACID (USP-RS), ENANTHIC ACID [USP-RS], HEPTANOIC-2,2-D2 ACID, CAS-111-14-8, SHV, 1219802-86-4, 352431-36-8, TESTOSTERONE ENANTATE IMPURITY A (EP IMPURITY), TESTOSTERONE ENANTATE IMPURITY A [EP IMPURITY], Heptansaeure, Oenanthsaeure, Cynergy, Hexacid, heptanoic-acid, Artec, WinterCare, Cynergy Barrier, Winter Dip, 1-heptanoic acid, Chem-Star Recover, Acid C7 heptanoic, DKL, Heptanoic Acid Anion, Heptanoic--d7 Acid, hexane carboxylic acid, Chem-Star Code Green, Heptanoic acid, 96%, hexane-1-carboxylic acid, Chem-Star Barrier 710, Heptanoic acid, >=97%, SCHEMBL3564, WLN: QV6, 5-HEXACID C-7, HEPTANOIC ACID [MI], NCIOpen2_005395, Heptanoic acid, 97%, FG, Heptanoic acid, natural, FG, MLS002415755, CH3-(CH2)5-COOH, HEPTANOIC ACID [FHFI], HEPTANOIC ACID [HSDB], CHEMBL320358, HMS2267D15, Heptanoic acid, analytical standard, AMY41347, Tox21_201830, Tox21_300342, FA 7:0, Heptanoic acid, >=98.0% (GC), Heptanoic acid, >=99.0% (GC), LMFA01010007, AKOS000119950, DB02938, HEPTANOIC ACID (ENANTIC ACID), NCGC00091189-01, NCGC00091189-02, NCGC00091189-03, NCGC00254267-01, NCGC00259379-01, SMR001261667, H0030, NS00010236, EN300-19601, C17714, Q297592, Q-201191, E3F2CC4A-F2B5-4353-8922-355FA750FEAC, F0001-0233, Z104474412, Enanthic Acid, United States Pharmacopeia (USP) Reference Standard, InChI=1/C7H14O2/c1-2-3-4-5-6-7(8)9/h2-6H2,1H3,(H,8,9, n-heptanoic acid, 111-14-8 [RN], 1744723 [Beilstein], 1-heptanoic acid, 203-838-7 [EINECS], Acide heptanoïque [French] [ACD/IUPAC Name], Acido eptanoico [Italian], ácido heptanoico [Spanish], enanthic acid, Enanthyl alcohol, Heptanoic acid [ACD/Index Name] [ACD/IUPAC Name], Heptansäure [German] [ACD/IUPAC Name], MFCD00004426 [MDL number], Oenanthic acid, 101488-09-9 [RN], 1219802-86-4 [RN], 130348-93-5 [RN], 156779-04-3 [RN], 1-Hexanecarboxylic acid, 2,2-Dideuterioheptanoic acid, 352431-36-8 [RN], 4-02-00-00214 [Beilstein], 4-02-00-00958 (Beilstein Handbook Reference) [Beilstein], 64118-38-3 [RN], C17714, C7:0, EINECS 203-838-7, Enanthoic acid, Enanthylic acid, Heptanoic-2,2-d2 Acid, Heptanoic-5,5,6,6,7,7,7-d7Acid, heptanoicacid, Heptanoic--d7 Acid, Heptansaeure, Hepthlic acid, heptoic acid, heptylic acid, KZH, Nat.Heptanoic Acid, n-Heptoic acid, n-Heptylic acid, Oenanthsaeure, oenanthylic acid, QV6 [WLN], sec-Heptanoic acid, SHV, TECHNETIUM MEDRONATE, WLN: QV6, 庚酸 [Chinese]

Heptanoic acid is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid functional group.
Heptanoic acid is a colorless oily liquid with an unpleasant, rancid odor.
Heptanoic acid contributes to the odor of some rancid oils.

Heptanoic acid is slightly soluble in water, but very soluble in ethanol and ether.
Salts and esters of Heptanoic acid are called enanthates or heptanoates.

Heptanoic acid, belongs to the class of organic compounds known as medium-chain fatty acids.
Medium-chain fatty acids (MCFA) are fatty acids with aliphatic tails of 6 to 12 carbons, which can form medium-chain triglycerides Heptanoic acid is an oily liquid with an unpleasant, rancid odor.

Heptanoic acid contributes to the odor of some rancid oils.
Heptanoic acid is slightly soluble in water, but very soluble in ethanol and ether.

Heptanoic acid's name derives from the Latin oenanthe which is in turn derived from the Ancient Greek oinos "wine" and anthos "blossom."
Heptanoic acid is used in the preparation of esters, such as ethyl enanthate, which are used in fragrances and as artificial flavors.
The triglyceride ester of Heptanoic acid is the triheptanoin, which is used in certain medical conditions as a nutritional supplement.

Heptanoic acid appears as a colorless liquid with a pungent odor.
Heptanoic acid is less dense than water and poorly soluble in water.

Heptanoic acid is hence floats on water.
Heptanoic acid is very corrosive.

Heptanoic acid contact may likely burn skin, eyes, and mucous membranes.
Heptanoic acid may be toxic by ingestion, inhalation and skin absorption.
Heptanoic acid flash point near 200 °F.

Heptanoic acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Heptanoic acid is used at industrial sites and in manufacturing.

Heptanoic acid is a versatile compound with various characteristics and applications.
Heptanoic acid is a medium-chain saturated fatty acid and a straight-chain carboxylic acid.

The catalytic ketonisation of Heptanoic acid has been investigated using Mn, Ce, and Zr oxides supported on Al2O3, SiO2, and TiO2.
These studies shed light on the conversion of Heptanoic acid into ketones facilitated by these catalysts.

Heptanoic acid is used as an organic building block for the synthesis of a variety of chemical compounds.
Heptanoic acid is involved in the esterification of steroids and used in the preparation of active pharmaceutical ingredients such as trenbolone enanthate, testosterone enanthate, drostanolone enanthate and methenolone enanthate.
Heptanoic acid is also used as an internal standard during gas chromatography analysis of the butyl esters of volatile acids.

Heptanoic acids ester derivatives are used in the fragrance and flavor industries as well as cosmetics and industrial lubricants in aviation, refrigeration and automobile.
Heptanoic acid is used to prepare sodium heptanoate, which is used as a corrosion inhibitor.

Belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.

Heptanoic acid, is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid.
Heptanoic acid is found in many foods, some of which are soup, sauce, scallop, and leek.

Heptanoic acid, straight-chain fatty acid that contributes to the odour of some rancid oils.
The methyl ester of ricinoleic acid, obtained from castor bean oil, is the main commercial precursor to Heptanoic acid.

Heptanoic acid is pyrolyzed to the methyl ester of 10-undecenoic acid and heptanal, which is then air-oxidized to the carboxylic acid.
Approximately 20,000 tons were consumed in Europe and US in 1980.

Heptanoic acid appears as a colorless liquid with a pungent odor.

Heptanoic acid is an aliphatic carboxylic acid, used in the synthesis of esters for products such as fragrances and artificial flavor preparations.
Heptanoic acid, straight-chain fatty acid that contributes to the odour of some rancid oils.

Heptanoic acid used in the preparation of esters for the fragrance industry, and as an additive in cigarettes.
Heptanoic acid has a role as a plant metabolite.

Heptanoic acid is a medium-chain fatty acid and a straight-chain saturated fatty acid.
Heptanoic acid is a conjugate acid of a heptanoate.

Heptanoic acid, belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.

This high purity fatty acid methyl ester is ideal as a standard and for biological studies.
Hexanoic acid is a short-chain fatty acid that has important biological functions and properties.

Heptanoic acid has been demonstrated to be able to induce resistance in some plants against certain bacteria and fungi.
Heptanoic acid is a 100% linear chain saturated fatty acid, 100% of vegetal origin, processed from castor oil.

Heptanoic acid, is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid.

The Methyl Ester of Ricinoleic Acid, obtained from castor bean oil is the main commercial precursor to Heptanoic acid.
Heptanoic acid is a fatty acid and is widely distributed in nature as a component of animal and vegetable fats.

Heptanoic acid is an organic compound composed of seven-carbon chain terminating in a carboxylic acid.

Uses of Heptanoic acid:
Heptanoic acid is used in the preparation of esters, such as ethyl enanthate, which are used in fragrances and as artificial flavors.
Heptanoic acid is used to esterify steroids in the preparation of drugs such as testosterone enanthate, trenbolone enanthate, drostanolone enanthate, and methenolone enanthate (Primobolan).

The triglyceride ester of Heptanoic acid is the triheptanoin, which is used in certain medical conditions as a nutritional supplement.

Heptanoic acid is present in essential oils, e.g. violet leaf oil, palm oiland is also present in apple, feijoa fruit, strawberry jam, clove bud, ginger, black tea, morello cherry, grapes, rice bran and other foodstuffs.
Heptanoic acid is flavouring ingredient.

Heptanoic acid is used as one of the components in washing solns.
Heptanoic acid is used to assist lye peeling of fruit and vegetables.

Heptanoic acid, is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid.
Heptanoic acid is also one of many additives in cigarettes.

Heptanoic acid is used in the preparation of esters for the fragrance industry, and as an additive in cigarettes.
Heptanoic acid, can be used as an organic building blocks for the synthesis of variety of chemical compounds.

Heptanoic acid is used in the synthesis of 17-epi-Testosterone Enanthate.

Heptanoic acid is also one of many additives in cigarettes.
Heptanoic acid is Mainly used in the production of heptanoate, organic synthesis of basic raw materials, widely used in spices, pharmaceuticals, lubricants, plasticizers and other industries.

Esters in the fragrances and flavors industry, in cosmetics and for the industrial lubricants (aviation, refrigeration, automotive etc.)
Salts (sodium heptanoate) for corrosion inhibition.

Heptanoic acid is used as an organic building block for the synthesis of a variety of chemical compounds.
Heptanoic acid is involved in the esterification of steroids and used in the preparation of active pharmaceutical ingredients such as trenbolone enanthate, testosterone enanthate, drostanolone enanthate and methenolone enanthate.
Heptanoic acid is also used as an internal standard during gas chromatography analysis of the butyl esters of volatile acids.

Heptanoic acid's ester derivatives are used in the fragrance and flavor industries as well as cosmetics and industrial lubricants in aviation, refrigeration and automobile.
Heptanoic acid is used to prepare sodium heptanoate, which is used as a corrosion inhibitor.

Heptanoic acid is used in organic synthesis, in production of special lubricants for aircrafts and brake fluids and as a synthetic flavoring ingredient.
Heptanoic acid is used as perfuming agent in cosmetics.

Heptanoic acid is used in the following products: laboratory chemicals.
Heptanoic acid is used for the manufacture of: chemicals.
Release to the environment of Heptanoic acid can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates).

Industry Uses:
Lubricants and lubricant additives
Intermediate

Applications of Heptanoic acid:
Heptanoic acid is used as an organic building block for the synthesis of a variety of chemical compounds.
Heptanoic acid is involved in the esterification of steroids and used in the preparation of active pharmaceutical ingredients such as trenbolone enanthate, testosterone enanthate, drostanolone enanthate and methenolone enanthate.

Heptanoic acid is also used as an internal standard during gas chromatography analysis of the butyl esters of volatile acids.
Heptanoic acids ester derivatives are used in the fragrance and flavor industries as well as cosmetics and industrial lubricants in aviation, refrigeration and automobile.
Heptanoic acid is used to prepare sodium heptanoate, which is used as a corrosion inhibitor.

Heptanoic acid can be used:
For esterification with glycerol to synthesize a triacylglycerol called as triheptanoin or trienanthoin.
To synthesize 1-hexene via decarbonylation reaction by using platinum nanoparticles supported on carbon.
To synthesize 7-tridecanone by ketonization in the presence of MnO2/CeO2 or ZrO2 catalysts supported on the surface of alumina.

Production of Heptanoic acid:

The methyl ester of ricinoleic acid, obtained from castor bean oil, is the main commercial precursor to Heptanoic acid.
Heptanoic acid is pyrolyzed to the methyl ester of 10-undecenoic acid and heptanal, which is then air-oxidized to the carboxylic acid.
Approximately 20,000 tons were consumed in Europe and US in 1980.

Laboratory preparations of Heptanoic acid include permanganate oxidation of heptanal and 1-octene.

General Manufacturing Information of Heptanoic acid:

Industry Processing Sectors:
All Other Chemical Product and Preparation Manufacturing
Petroleum Lubricating Oil and Grease Manufacturing
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
All Other Basic Organic Chemical Manufacturing

Handling and storage of Heptanoic acid:

Precautions for safe handling:

Advice on safe handling:
Work under hood.
Do not inhale substance/mixture.
Avoid generation of vapours/aerosols.

Hygiene measures:
Immediately change contaminated clothing
Apply preventive skin protection.
Wash hands and face after working with substance.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Tightly closed.

Storage class:
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Stability and reactivity of Heptanoic acid:

Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Chemical stability
Heptanoic acid is chemically stable under standard ambient conditions (room temperature).

Possibility of hazardous reactions:

Violent reactions possible with:
Alkalines
Strong oxidizing agents

Conditions to avoid:
Strong heating.

Incompatible materials:
Nonferrous metals, Mild steel

Safety
Heptanoic acid is toxic if swallowed and corrosive.

First aid measures of Heptanoic acid:

General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.

If inhaled:

After inhalation:
Fresh air.
Immediately call in physician.

If breathing stops:
Immediately apply artificial respiration, if necessary also oxygen.

In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.

In case of eye contact:

After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.

If swallowed:

After swallowing:
Make victim drink water (two glasses at most), avoid vomiting (risk of perforation).
Call a physician immediately.
Do not attempt to neutralise.

Indication of any immediate medical attention and special treatment needed:
No data available

Firefighting measures of Heptanoic acid:

Suitable extinguishing media:
Carbon dioxide (CO2) Foam Dry powder

Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from Heptanoic acid or mixture:
Carbon oxides
Combustible.

Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters:
Stay in danger area only with self-contained breathing apparatus.
Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

Accidental release measures of Heptanoic acid:

Personal precautions, protective equipment and emergency procedures:

Advice for non-emergency personnel:
Do not breathe vapors, aerosols.
Avoid substance contact.

Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.

Observe possible material restrictions.
Take up with liquid-absorbent material.

Dispose of properly.
Clean up affected area.

Spillage Disposal of Heptanoic acid:

Personal protection:
Complete protective clothing including self-contained breathing apparatus.
Collect leaking and spilled liquid in sealable containers as far as possible.

Absorb remaining liquid in sand or inert absorbent.
Then store and dispose of according to local regulations.

Disposal Methods of Heptanoic acid:
The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination.
Recycle any unused portion of the material for Heptanoic acids approved use or return it to the manufacturer or supplier.

Ultimate disposal of the chemical must consider:
Heptanoic acid's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Collect leaking liquid in sealable containers.
Absorb remaining liquid in sand or inert absorbent and remove to safe place (extra personal protection: complete protective clothing including self-contained breathing apparatus).

Identifiers of Heptanoic acid:
CAS Number: 111-14-8
ChEBI: CHEBI:45571
ChEMBL: ChEMBL320358
ChemSpider: 7803
DrugBank: DB02938
ECHA InfoCard: 100.003.490
KEGG: C17714
PubChem CID: 8094
UNII: THE3YNP39D
CompTox Dashboard (EPA): DTXSID2021600
InChI: InChI=1S/C7H14O2/c1-2-3-4-5-6-7(8)9/h2-6H2,1H3,(H,8,9)
Key: MNWFXJYAOYHMED-UHFFFAOYSA-N
InChI=1/C7H14O2/c1-2-3-4-5-6-7(8)9/h2-6H2,1H3,(H,8,9)
Key: MNWFXJYAOYHMED-UHFFFAOYAP
SMILES: O=C(O)CCCCCC

CAS number: 111-14-8
EC index number: 607-196-00-2
EC number: 203-838-7
Hill Formula: C₇H₁₄O₂
Chemical formula: CH₃(CH₂)₅COOH
Molar Mass: 130.19 g/mol
HS Code: 2915 90 90

Synonym(s):Heptanoic acid, OHeptanoic acid
Linear Formula: CH3(CH2)5COOH
CAS Number: 111-14-8
Molecular Weight: 130.18
Beilstein: 1744723
EC Number: 203-838-7
MDL number: MFCD00004426
PubChem Substance ID: 57652556
NACRES: NA.22

Properties of Heptanoic acid:
Chemical formula: C7H14O2
Molar mass: 130.187 g·mol−1
Appearance: colorless oily liquid
Density: 0.9181 g/cm3 (20 °C)
Melting point: −7.5 °C (18.5 °F; 265.6 K)
Boiling point: 223 °C (433 °F; 496 K)
Solubility in water: 0.2419 g/100 mL (15 °C)
Magnetic susceptibility (χ): −88.60·10−6 cm3/mol

Density: 0.92 g/cm3 (20 °C)
Flash point: 113 °C
Ignition temperature: 380 °C
Melting Point: -10.5 °C
Vapor pressure: Viscosity kinematic: 5.00 mm2/s (20 °C)
Solubility: 2.8 g/l

Molecular Weight: 130.18 g/mol
XLogP3: 2.5
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 5
Exact Mass: 130.099379685 g/mol
Monoisotopic Mass: 130.099379685 g/mol
Topological Polar Surface Area: 37.3Ų
Heavy Atom Count: 9
Complexity: 79
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

vapor density: 4.5 (vs air)
Quality Level: 200
vapor pressure: Assay: ≥99.0% (GC)
form: liquid
expl. lim.: 10.1 %

refractive index:
n20/D 1.4221 (lit.)
n20/D 1.423

bp: 223 °C (lit.)
mp: −10.5 °C (lit.)
density: 0.918 g/mL at 25 °C (lit.)
SMILES string: CCCCCCC(O)=O
InChI: 1S/C7H14O2/c1-2-3-4-5-6-7(8)9/h2-6H2,1H3,(H,8,9)
InChI key: MNWFXJYAOYHMED-UHFFFAOYSA-N

Specifications of Heptanoic acid:
Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.917 - 0.919
Identity (IR): passes test

Related compounds of Heptanoic acid:
Hexanoic acid
Octanoic acid

Alternative Parents of Heptanoic acid:
Straight chain fatty acids
Monocarboxylic acids and derivatives
Carboxylic acids
Organic oxides
Hydrocarbon derivatives
Carbonyl compounds

Substituents of Heptanoic acid:
Medium-chain fatty acid
Straight chain fatty acid
Monocarboxylic acid or derivatives
Carboxylic acid
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aliphatic acyclic compound

Names of Heptanoic acid:

Regulatory process names:
Heptanoic acid
Heptanoic acid
heptanoic acid

Translated names:
acid heptanoic (ro)
acide heptanoïque (fr)
acido eptanoico (it)
Heptaanhape (et)
Heptaanihappo (fi)
heptaanzuur (nl)
heptano rūgštis (lt)
heptanojska kislina (sl)
heptanonska kiselina (hr)
heptanová kyselina (cs)
heptansyra (sv)
heptansyre (da)
heptansyre (no)
Heptansäure (de)
heptánsav (hu)
heptānskābe (lv)
kwas heptanowy kwas enantowy kwas heksanokarboksylowy (pl)
kyselina heptánová (sk)
ácido heptanoico (es)
ácido heptanóico (pt)
επτανοϊκό οξύ (el)
хептанова киселина (bg)

Preferred IUPAC name:
Heptanoic acid

IUPAC names:
HEPTANOIC ACID
Heptanoic Acid
Heptanoic acid
heptanoic acid
Heptanoic acid
heptanoic acid

Other names:
Enthanoic acid
Enthanylic acid
Heptoic acid
Heptylic acid
Oenanthic acid
Oenanthylic acid
1-Hexanecarboxylic acid
C7:0 (lipid numbers)

Other identifiers:
111-14-8
607-196-00-2
HEPTHLIC ACID
Hepthlic acid is used in the preparation of esters, such as ethyl enanthate, which are used in fragrances and as artificial flavors.
Hepthlic acid is involved in the esterification of steroids and used in the preparation of active pharmaceutical ingredients such as trenbolone enanthate, testosterone enanthate, drostanolone enanthate, and methenolone enanthate.
Hepthlic acid's ester derivatives are used in the fragrance and flavor industries as well as cosmetics and industrial lubricants in aviation, refrigeration, and automobiles.

CAS number: 111-14-8
EC number: 203-838-7
Chemical formula: CH₃(CH₂)₅COOH
Molar Mass: 130.19 g/mol

Synonyms: HEPTANOIC ACID, 111-14-8, Enanthic acid, n-Heptanoic acid, Oenanthic acid, Enanthylic acid, Heptoic acid, n-Heptylic acid, n-Heptoic acid, Heptylic acid, Oenanthylic acid, 1-Hexanecarboxylic acid, Hexacid C-7, FEMA No. 3348, Heptanoic acid (natural), NSC 2192, CCRIS 6042, enanthoic acid, Hepthlic acid, HSDB 5546, UNII-THE3YNP39D, THE3YNP39D, EINECS 203-838-7, MFCD00004426, Technetium Medronate, BRN 1744723, DTXSID2021600, CHEBI:45571, AI3-02073, Artec ultra conditioning teat dip, HEPTANOIC AICD-, NSC-2192, DTXCID301600, NSC2192, EC 203-838-7, 4-02-00-00958 (Beilstein Handbook Reference), C7:0, sec-Heptanoic acid, 101488-09-9, ENANTHIC ACID (USP-RS), ENANTHIC ACID [USP-RS], HEPTANOIC-2,2-D2 ACID, CAS-111-14-8, SHV, 1219802-86-4, 352431-36-8, TESTOSTERONE ENANTATE IMPURITY A (EP IMPURITY), TESTOSTERONE ENANTATE IMPURITY A [EP IMPURITY], Heptansaeure, Oenanthsaeure, Cynergy, Hexacid, heptanoic-acid, Artec, WinterCare, Cynergy Barrier, Winter Dip, 1-heptanoic acid, Chem-Star Recover, Acid C7 heptanoic, DKL, Heptanoic Acid Anion, Heptanoic--d7 Acid, hexane carboxylic acid, Chem-Star Code Green, Heptanoic acid, 96%, hexane-1-carboxylic acid, Chem-Star Barrier 710, Heptanoic acid, >=97%, SCHEMBL3564, WLN: QV6, 5-HEXACID C-7, HEPTANOIC ACID [MI], NCIOpen2_005395, Heptanoic acid, 97%, FG, Heptanoic acid, natural, FG, MLS002415755, CH3-(CH2)5-COOH, HEPTANOIC ACID [FHFI], HEPTANOIC ACID [HSDB], CHEMBL320358, HMS2267D15, Heptanoic acid, analytical standard, AMY41347, Tox21_201830, Tox21_300342, FA 7:0, Heptanoic acid, >=98.0% (GC), Heptanoic acid, >=99.0% (GC), LMFA01010007, AKOS000119950, DB02938, HEPTANOIC ACID (ENANTIC ACID), NCGC00091189-01, NCGC00091189-02, NCGC00091189-03, NCGC00254267-01, NCGC00259379-01, SMR001261667, H0030, NS00010236, EN300-19601, C17714, Q297592, Q-201191, E3F2CC4A-F2B5-4353-8922-355FA750FEAC, F0001-0233, Z104474412, Enanthic Acid, United States Pharmacopeia (USP) Reference Standard, InChI=1/C7H14O2/c1-2-3-4-5-6-7(8)9/h2-6H2,1H3,(H,8,9, n-heptanoic acid, 111-14-8 [RN], 1744723 [Beilstein], 1-heptanoic acid, 203-838-7 [EINECS], Acide heptanoïque [French] [ACD/IUPAC Name], Acido eptanoico [Italian], ácido heptanoico [Spanish], enanthic acid, Enanthyl alcohol, Heptanoic acid [ACD/Index Name] [ACD/IUPAC Name], Heptansäure [German] [ACD/IUPAC Name], MFCD00004426 [MDL number], Oenanthic acid, 101488-09-9 [RN], 1219802-86-4 [RN], 130348-93-5 [RN], 156779-04-3 [RN], 1-Hexanecarboxylic acid, 2,2-Dideuterioheptanoic acid, 352431-36-8 [RN], 4-02-00-00214 [Beilstein], 4-02-00-00958 (Beilstein Handbook Reference) [Beilstein], 64118-38-3 [RN], C17714, C7:0, EINECS 203-838-7, Enanthoic acid, Enanthylic acid, Heptanoic-2,2-d2 Acid, Heptanoic-5,5,6,6,7,7,7-d7Acid, heptanoicacid, Heptanoic--d7 Acid, Heptansaeure, Hepthlic acid, heptoic acid, heptylic acid, KZH, Nat.Heptanoic Acid, n-Heptoic acid, n-Heptylic acid, Oenanthsaeure, oenanthylic acid, QV6 [WLN], sec-Heptanoic acid, SHV, TECHNETIUM MEDRONATE, WLN: QV6, 庚酸 [Chinese]

Hepthlic acid is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid functional group.
Hepthlic acid is a colorless oily liquid with an unpleasant, rancid odor.
Hepthlic acid contributes to the odor of some rancid oils.

Hepthlic acid is slightly soluble in water, but very soluble in ethanol and ether.
Salts and esters of Hepthlic acid are called enanthates or heptanoates.

Hepthlic acid, belongs to the class of organic compounds known as medium-chain fatty acids.
Medium-chain fatty acids (MCFA) are fatty acids with aliphatic tails of 6 to 12 carbons, which can form medium-chain triglycerides Hepthlic acid is an oily liquid with an unpleasant, rancid odor.

Hepthlic acid contributes to the odor of some rancid oils.
Hepthlic acid is slightly soluble in water, but very soluble in ethanol and ether.

Hepthlic acid's name derives from the Latin oenanthe which is in turn derived from the Ancient Greek oinos "wine" and anthos "blossom."
Hepthlic acid is used in the preparation of esters, such as ethyl enanthate, which are used in fragrances and as artificial flavors.
The triglyceride ester of Hepthlic acid is the triheptanoin, which is used in certain medical conditions as a nutritional supplement.

Hepthlic acid appears as a colorless liquid with a pungent odor.
Hepthlic acid is less dense than water and poorly soluble in water.

Hepthlic acid is hence floats on water.
Hepthlic acid is very corrosive.

Hepthlic acid contact may likely burn skin, eyes, and mucous membranes.
Hepthlic acid may be toxic by ingestion, inhalation and skin absorption.
Hepthlic acid flash point near 200 °F.

Hepthlic acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Hepthlic acid is used at industrial sites and in manufacturing.

Hepthlic acid is a versatile compound with various characteristics and applications.
Hepthlic acid is a medium-chain saturated fatty acid and a straight-chain carboxylic acid.

The catalytic ketonisation of Hepthlic acid has been investigated using Mn, Ce, and Zr oxides supported on Al2O3, SiO2, and TiO2.
These studies shed light on the conversion of Hepthlic acid into ketones facilitated by these catalysts.

Hepthlic acid is used as an organic building block for the synthesis of a variety of chemical compounds.
Hepthlic acid is involved in the esterification of steroids and used in the preparation of active pharmaceutical ingredients such as trenbolone enanthate, testosterone enanthate, drostanolone enanthate and methenolone enanthate.
Hepthlic acid is also used as an internal standard during gas chromatography analysis of the butyl esters of volatile acids.

Hepthlic acids ester derivatives are used in the fragrance and flavor industries as well as cosmetics and industrial lubricants in aviation, refrigeration and automobile.
Hepthlic acid is used to prepare sodium heptanoate, which is used as a corrosion inhibitor.

Belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.

Hepthlic acid, is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid.
Hepthlic acid is found in many foods, some of which are soup, sauce, scallop, and leek.

Hepthlic acid, straight-chain fatty acid that contributes to the odour of some rancid oils.
The methyl ester of ricinoleic acid, obtained from castor bean oil, is the main commercial precursor to Hepthlic acid.

Hepthlic acid is pyrolyzed to the methyl ester of 10-undecenoic acid and heptanal, which is then air-oxidized to the carboxylic acid.
Approximately 20,000 tons were consumed in Europe and US in 1980.

Hepthlic acid appears as a colorless liquid with a pungent odor.

Hepthlic acid is an aliphatic carboxylic acid, used in the synthesis of esters for products such as fragrances and artificial flavor preparations.
Hepthlic acid, straight-chain fatty acid that contributes to the odour of some rancid oils.

Hepthlic acid used in the preparation of esters for the fragrance industry, and as an additive in cigarettes.
Hepthlic acid has a role as a plant metabolite.

Hepthlic acid is a medium-chain fatty acid and a straight-chain saturated fatty acid.
Hepthlic acid is a conjugate acid of a heptanoate.

Hepthlic acid, belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.

This high purity fatty acid methyl ester is ideal as a standard and for biological studies.
Hexanoic acid is a short-chain fatty acid that has important biological functions and properties.

Hepthlic acid has been demonstrated to be able to induce resistance in some plants against certain bacteria and fungi.
Hepthlic acid is a 100% linear chain saturated fatty acid, 100% of vegetal origin, processed from castor oil.

Hepthlic acid, is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid.

The Methyl Ester of Ricinoleic Acid, obtained from castor bean oil is the main commercial precursor to Hepthlic acid.
Hepthlic acid is a fatty acid and is widely distributed in nature as a component of animal and vegetable fats.

Hepthlic acid is an organic compound composed of seven-carbon chain terminating in a carboxylic acid.

Uses of Hepthlic acid:
Hepthlic acid is used in the preparation of esters, such as ethyl enanthate, which are used in fragrances and as artificial flavors.
Hepthlic acid is used to esterify steroids in the preparation of drugs such as testosterone enanthate, trenbolone enanthate, drostanolone enanthate, and methenolone enanthate (Primobolan).

The triglyceride ester of Hepthlic acid is the triheptanoin, which is used in certain medical conditions as a nutritional supplement.

Hepthlic acid is present in essential oils, e.g. violet leaf oil, palm oiland is also present in apple, feijoa fruit, strawberry jam, clove bud, ginger, black tea, morello cherry, grapes, rice bran and other foodstuffs.
Hepthlic acid is flavouring ingredient.

Hepthlic acid is used as one of the components in washing solns.
Hepthlic acid is used to assist lye peeling of fruit and vegetables.

Hepthlic acid, is an organic compound composed of a seven-carbon chain terminating in a carboxylic acid.
Hepthlic acid is also one of many additives in cigarettes.

Hepthlic acid is used in the preparation of esters for the fragrance industry, and as an additive in cigarettes.
Hepthlic acid, can be used as an organic building blocks for the synthesis of variety of chemical compounds.

Hepthlic acid is used in the synthesis of 17-epi-Testosterone Enanthate.

Hepthlic acid is also one of many additives in cigarettes.
Hepthlic acid is Mainly used in the production of heptanoate, organic synthesis of basic raw materials, widely used in spices, pharmaceuticals, lubricants, plasticizers and other industries.

Esters in the fragrances and flavors industry, in cosmetics and for the industrial lubricants (aviation, refrigeration, automotive etc.)
Salts (sodium heptanoate) for corrosion inhibition.

Hepthlic acid is used as an organic building block for the synthesis of a variety of chemical compounds.
Hepthlic acid is involved in the esterification of steroids and used in the preparation of active pharmaceutical ingredients such as trenbolone enanthate, testosterone enanthate, drostanolone enanthate and methenolone enanthate.
Hepthlic acid is also used as an internal standard during gas chromatography analysis of the butyl esters of volatile acids.

Hepthlic acid's ester derivatives are used in the fragrance and flavor industries as well as cosmetics and industrial lubricants in aviation, refrigeration and automobile.
Hepthlic acid is used to prepare sodium heptanoate, which is used as a corrosion inhibitor.

Hepthlic acid is used in organic synthesis, in production of special lubricants for aircrafts and brake fluids and as a synthetic flavoring ingredient.
Hepthlic acid is used as perfuming agent in cosmetics.

Hepthlic acid is used in the following products: laboratory chemicals.
Hepthlic acid is used for the manufacture of: chemicals.
Release to the environment of Hepthlic acid can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates).

Industry Uses:
Lubricants and lubricant additives
Intermediate

Applications of Hepthlic acid:
Hepthlic acid is used as an organic building block for the synthesis of a variety of chemical compounds.
Hepthlic acid is involved in the esterification of steroids and used in the preparation of active pharmaceutical ingredients such as trenbolone enanthate, testosterone enanthate, drostanolone enanthate and methenolone enanthate.

Hepthlic acid is also used as an internal standard during gas chromatography analysis of the butyl esters of volatile acids.
Hepthlic acids ester derivatives are used in the fragrance and flavor industries as well as cosmetics and industrial lubricants in aviation, refrigeration and automobile.
Hepthlic acid is used to prepare sodium heptanoate, which is used as a corrosion inhibitor.

Hepthlic acid can be used:
For esterification with glycerol to synthesize a triacylglycerol called as triheptanoin or trienanthoin.
To synthesize 1-hexene via decarbonylation reaction by using platinum nanoparticles supported on carbon.
To synthesize 7-tridecanone by ketonization in the presence of MnO2/CeO2 or ZrO2 catalysts supported on the surface of alumina.

Production of Hepthlic acid:

The methyl ester of ricinoleic acid, obtained from castor bean oil, is the main commercial precursor to Hepthlic acid.
Hepthlic acid is pyrolyzed to the methyl ester of 10-undecenoic acid and heptanal, which is then air-oxidized to the carboxylic acid.
Approximately 20,000 tons were consumed in Europe and US in 1980.

Laboratory preparations of Hepthlic acid include permanganate oxidation of heptanal and 1-octene.

General Manufacturing Information of Hepthlic acid:

Industry Processing Sectors:
All Other Chemical Product and Preparation Manufacturing
Petroleum Lubricating Oil and Grease Manufacturing
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
All Other Basic Organic Chemical Manufacturing

Handling and storage of Hepthlic acid:

Precautions for safe handling:

Advice on safe handling:
Work under hood.
Do not inhale substance/mixture.
Avoid generation of vapours/aerosols.

Hygiene measures:
Immediately change contaminated clothing
Apply preventive skin protection.
Wash hands and face after working with substance.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Tightly closed.

Storage class:
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Stability and reactivity of Hepthlic acid:

Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Chemical stability
Hepthlic acid is chemically stable under standard ambient conditions (room temperature).

Possibility of hazardous reactions:

Violent reactions possible with:
Alkalines
Strong oxidizing agents

Conditions to avoid:
Strong heating.

Incompatible materials:
Nonferrous metals, Mild steel

Safety
Hepthlic acid is toxic if swallowed and corrosive.

First aid measures of Hepthlic acid:

General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.

If inhaled:

After inhalation:
Fresh air.
Immediately call in physician.

If breathing stops:
Immediately apply artificial respiration, if necessary also oxygen.

In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.

In case of eye contact:

After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.

If swallowed:

After swallowing:
Make victim drink water (two glasses at most), avoid vomiting (risk of perforation).
Call a physician immediately.
Do not attempt to neutralise.

Indication of any immediate medical attention and special treatment needed:
No data available

Firefighting measures of Hepthlic acid:

Suitable extinguishing media:
Carbon dioxide (CO2) Foam Dry powder

Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from Hepthlic acid or mixture:
Carbon oxides
Combustible.

Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters:
Stay in danger area only with self-contained breathing apparatus.
Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

Accidental release measures of Hepthlic acid:

Personal precautions, protective equipment and emergency procedures:

Advice for non-emergency personnel:
Do not breathe vapors, aerosols.
Avoid substance contact.

Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.

Observe possible material restrictions.
Take up with liquid-absorbent material.

Dispose of properly.
Clean up affected area.

Spillage Disposal of Hepthlic acid:

Personal protection:
Complete protective clothing including self-contained breathing apparatus.
Collect leaking and spilled liquid in sealable containers as far as possible.

Absorb remaining liquid in sand or inert absorbent.
Then store and dispose of according to local regulations.

Disposal Methods of Hepthlic acid:
The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination.
Recycle any unused portion of the material for Hepthlic acids approved use or return it to the manufacturer or supplier.

Ultimate disposal of the chemical must consider:
Hepthlic acid's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Collect leaking liquid in sealable containers.
Absorb remaining liquid in sand or inert absorbent and remove to safe place (extra personal protection: complete protective clothing including self-contained breathing apparatus).

Identifiers of Hepthlic acid:
CAS Number: 111-14-8
ChEBI: CHEBI:45571
ChEMBL: ChEMBL320358
ChemSpider: 7803
DrugBank: DB02938
ECHA InfoCard: 100.003.490
KEGG: C17714
PubChem CID: 8094
UNII: THE3YNP39D
CompTox Dashboard (EPA): DTXSID2021600
InChI: InChI=1S/C7H14O2/c1-2-3-4-5-6-7(8)9/h2-6H2,1H3,(H,8,9)
Key: MNWFXJYAOYHMED-UHFFFAOYSA-N
InChI=1/C7H14O2/c1-2-3-4-5-6-7(8)9/h2-6H2,1H3,(H,8,9)
Key: MNWFXJYAOYHMED-UHFFFAOYAP
SMILES: O=C(O)CCCCCC

CAS number: 111-14-8
EC index number: 607-196-00-2
EC number: 203-838-7
Hill Formula: C₇H₁₄O₂
Chemical formula: CH₃(CH₂)₅COOH
Molar Mass: 130.19 g/mol
HS Code: 2915 90 90

Synonym(s):Hepthlic acid, OHepthlic acid
Linear Formula: CH3(CH2)5COOH
CAS Number: 111-14-8
Molecular Weight: 130.18
Beilstein: 1744723
EC Number: 203-838-7
MDL number: MFCD00004426
PubChem Substance ID: 57652556
NACRES: NA.22

Properties of Hepthlic acid:
Chemical formula: C7H14O2
Molar mass: 130.187 g·mol−1
Appearance: colorless oily liquid
Density: 0.9181 g/cm3 (20 °C)
Melting point: −7.5 °C (18.5 °F; 265.6 K)
Boiling point: 223 °C (433 °F; 496 K)
Solubility in water: 0.2419 g/100 mL (15 °C)
Magnetic susceptibility (χ): −88.60·10−6 cm3/mol

Density: 0.92 g/cm3 (20 °C)
Flash point: 113 °C
Ignition temperature: 380 °C
Melting Point: -10.5 °C
Vapor pressure: Viscosity kinematic: 5.00 mm2/s (20 °C)
Solubility: 2.8 g/l

Molecular Weight: 130.18 g/mol
XLogP3: 2.5
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 5
Exact Mass: 130.099379685 g/mol
Monoisotopic Mass: 130.099379685 g/mol
Topological Polar Surface Area: 37.3Ų
Heavy Atom Count: 9
Complexity: 79
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

vapor density: 4.5 (vs air)
Quality Level: 200
vapor pressure: Assay: ≥99.0% (GC)
form: liquid
expl. lim.: 10.1 %

refractive index:
n20/D 1.4221 (lit.)
n20/D 1.423

bp: 223 °C (lit.)
mp: −10.5 °C (lit.)
density: 0.918 g/mL at 25 °C (lit.)
SMILES string: CCCCCCC(O)=O
InChI: 1S/C7H14O2/c1-2-3-4-5-6-7(8)9/h2-6H2,1H3,(H,8,9)
InChI key: MNWFXJYAOYHMED-UHFFFAOYSA-N

Specifications of Hepthlic acid:
Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.917 - 0.919
Identity (IR): passes test

Related compounds of Hepthlic acid:
Hexanoic acid
Octanoic acid

Alternative Parents of Hepthlic acid:
Straight chain fatty acids
Monocarboxylic acids and derivatives
Carboxylic acids
Organic oxides
Hydrocarbon derivatives
Carbonyl compounds

Substituents of Hepthlic acid:
Medium-chain fatty acid
Straight chain fatty acid
Monocarboxylic acid or derivatives
Carboxylic acid
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aliphatic acyclic compound

Names of Hepthlic acid:

Regulatory process names:
Hepthlic acid
Hepthlic acid
Hepthlic acid

Translated names:
acid heptanoic (ro)
acide heptanoïque (fr)
acido eptanoico (it)
Heptaanhape (et)
Heptaanihappo (fi)
heptaanzuur (nl)
heptano rūgštis (lt)
heptanojska kislina (sl)
heptanonska kiselina (hr)
heptanová kyselina (cs)
heptansyra (sv)
heptansyre (da)
heptansyre (no)
Heptansäure (de)
heptánsav (hu)
heptānskābe (lv)
kwas heptanowy kwas enantowy kwas heksanokarboksylowy (pl)
kyselina heptánová (sk)
ácido heptanoico (es)
ácido heptanóico (pt)
επτανοϊκό οξύ (el)
хептанова киселина (bg)

Preferred IUPAC name:
Hepthlic acid

IUPAC names:
Hepthlic acid
Hepthlic acid
Hepthlic acid
Hepthlic acid
Hepthlic acid
Hepthlic acid

Other names:
Enthanoic acid
Enthanylic acid
Heptoic acid
Heptylic acid
Oenanthic acid
Oenanthylic acid
1-Hexanecarboxylic acid
C7:0 (lipid numbers)

Other identifiers:
111-14-8
607-196-00-2
HEXA BUTYL DISTANNOXANE
Hexa butyl distannoxane is used in Anti Fouling Paints and Wood Preservatives.
Hexa butyl distannoxane appears as thin, colourless to pale yellow, flammable and combustible liquid.
Hexa butyl distannoxane is soluble in organic solvents.

CAS Number: 56-35-9
EC number: 200-268-0
Chemical formula: C24H54OSn2
Molar mass: 596.112

Synonyms: Tributyltin oxide, 56-35-9, BIS(TRIBUTYLTIN) OXIDE, TBTO, Hexabutyldistannoxane, Distannoxane, hexabutyl-, Bis(tributyltin)oxide, Bis(tri-n-butyltin) oxide, Lastanox Q, Butinox, Biomet, Mykolastanox F, Biomet 66, Stannicide A, Bis(tri-n-butyltin)oxide, Lastanox F, Lastanox T, Biomet TBTO, BioMeT SRM, Bis(tributylstannyl)oxide, Lastanox T 20, Tin, oxybis(tributyl-, Vikol AF-25, Vikol LO-25, Oxybis(tributylstannane), Hexabutyl distannoxane, Oxyde de tributyletain, C-Sn-9, Bis(tributyloxide) of tin, Bis-(tri-n-butylcin)oxid, Oxybis(tributyltin), Hexabutyldistannioxan, Bis(tri-N-butylzinn)-oxyd, Bis(tributylstannium) oxide, OTBE, Tin, bis(tributyl)-, oxide, Kyslicnik tri-N-butylcinicity, ENT 24,979, Stannane, tri-N-butyl-, oxide, tributyl(tributylstannyloxy)stannane, L.S. 3394, NSC 22332, Oxybis[tributyltin], UNII-3353Q84MKM, 6-Oxa-5,7-distannaundecane, 5,5,7,7-tetrabutyl-, Bis(tri-n-butyltin)oxide, technical grade, Stannane, oxide, 3353Q84MKM, MFCD00009418, Bis(tributyltin oxide), oxybis(tributyl tin), Oxybis[tributylstannane], Distannoxane, 1,1,1,3,3,3-hexabutyl-, bis(tributyl tin)oxide, OTBE, Caswell No. 101, 6-Oxa-5, 5,5,7,7-tetrabutyl-, C24H54OSn2, HBD, Hexabutyldistannioxan, CCRIS 3697, WLN: 4-SN-4&4&O-SN-4&4&4, HSDB 6505, Bis-(tri-n-butylcin)oxid , Bis(tri-n-butylzinn)-oxyd , EINECS 200-268-0, Tributyltin oxide (TBTO), Kyslicnik tri-n-butylcinicity , EPA Pesticide Chemical Code 083001, ZK 21995, tributyltinoxide, AI3-24979, tributyltin hydrate, Tributyl tin oxide, hexabutyidistannoxane, TBOT, Tributyltin(IV) oxide, (nBu3Sn)2O, DSSTox_CID_166, (Bu3Sn)2O, bis(tributyl stannyl)oxide, EC 200-268-0, bis (tri-n-butyltin) oxide, bis(tri-n-butylstannyl)oxide, DSSTox_RID_75413, DSSTox_GSID_20166, SCHEMBL19183, Keycide X-10 (Salt/Mix), bis(tri-n-butylstannyl) oxide, Bis[tri-n-butyltin(IV)]oxide, Bis(tributyltin) oxide, 96%i TBTO (Bis(tributyltin) oxide), DTXSID9020166, APQHKWPGGHMYKJ-UHFFFAOYSA-, CHEBI:81543, NSC22332, NSC28132, Tox21_203001, NSC-22332, NSC-28132, AKOS015909709, ZINC169743007, CAS-56-35-9, 1,1,1,3,3,3-Hexabutyldistannoxane #, NCGC00163942-01, NCGC00163942-02, NCGC00260546-01, BP-20397, TBTO, PESTANAL(R), analytical standard, FT-023098, V2250, C18149, A831016, Q3200-268-0 , 56-35-9 , Bis(tributyltin) oxide, Bis[tri-n-butyltin(IV)]oxide, BTO [Formula], Distannoxane, 1,1,1,3,3,3-hexabutyl- , HBD, Hexabutyldistannoxan, Hexabutyldistannoxane , Hexabutyldistannoxane, JN8750000, MFCD00009418, TBTO, Tributyltin oxide, Tributyltin(IV) oxide, [56-35-9] [RN], 1,1,1,3,3,3-Hexabutyldistannoxane, 200-268-0MFCD00009418, 6-Oxa-5,7-distannaundecane, 5,5,7,7-tetrabutyl-, Biomet [Trade name], Biomet 66, BioMet SRM, BioMet TBTO, Bis (tributyl tin) oxide, bis(tributyl tin)oxide, Bis(tributyloxide) of tin, Bis(tributylstannium) oxide, BIS(TRIBUTYLSTANNYL)OXIDE, Bis(tributyltin oxide), bis(tributyltin)oxide, Bis(tri-n-butyl tin)oxide, Bis-(tri-n-butylcin)oxid, Bis-(tri-n-butylcin)oxid, BIS(TRI-N-BUTYLTIN) OXIDE, BIS(TRI-n-BUTYLTIN)OXIDE, Bis(tri-N-butylzinn)-oxyd, Bis(tri-n-butylzinn), oxyd, Bis[tri-n-butyltin(IV)]oxide; HBD; Hexabutyldistannoxane; TBTO; Tributyltin(IV) oxide, BTBTO, Butinox, C005961, C-Sn-9, Distannoxane, hexabutyl-, EINECS 200-268-0, Hexabutyl distannoxane, Hexabutyldistannioxan, Hexabutyldistannioxan, Hexabutylditin, Keycide X-10 (Salt/Mix), Kyslicnik tri-N-butylcinicity, Kyslicnik tri-n-butylcinicity , L.S. 3394, Lastanox F, Lastanox Q, Lastanox T, Lastanox T 20, Mykolastanox F, NCGC00163942-01, OTBE, OTBE [French], oxybis(tributyl tin), Oxybis(tributylstannane), Oxybis(tributyltin), Oxybis[tributylstannane], Oxybis[tributyltin], Oxyde de tributyletain, Stannane, tri-n-butyl-, oxide, Stannicide A, TBOT, TBTO (Bis(tributyltin) oxide), Tin, bis(tributyl)-, oxide, Tributyl tin oxide, tributyl(tributylstannyloxy)stannane, tributyl[(tributylstannyl)oxy]stannane, Tributyltin oxide (TBTO), tributyl-tributylstannyloxystannane tributyl-tributylstannyloxy-stannane, Tri-n-butyltin oxide, Vikol AF-25, Vikol LO-25, WLN: 4-SN-4&4&O-SN-4&4&484794

Hexa butyl distannoxane is an organotin compound chiefly used as a biocide (fungicide and molluscicide), especially a wood preservative.
Hexa butyl distannoxane chemical formula is [(C4H9)3Sn]2O.

Hexa butyl distannoxane is a colorless viscous liquid.
Hexa butyl distannoxane is poorly soluble in water (20 ppm) but highly soluble in organic solvents.

Hexa butyl distannoxane is a potent skin irritant.
Hexa butyl distannoxane is an organotin compound chiefly used as a biocide (fungicide and molluscicide), especially a wood preservative.

Hexa butyl distannoxane chemical formula is [(C4H9)3Sn]2O.
Hexa butyl distannoxane has the form of a colorless to pale yellow liquid that is only slightly soluble in water (20 ppm) but highly soluble in organic solvents.

Hexa butyl distannoxane is used in Anti Fouling Paints and Wood Preservatives.
Tributyltin compounds had been used as marine anti-biofouling agents.

Historically, Hexa butyl distannoxane's biggest application was as a marine anti-biofouling agent.
Concerns over toxicity of these compounds have led to a worldwide ban by the International Maritime Organization.

Hexa butyl distannoxane is now considered a severe marine pollutant and a Substance of Very High Concern by the EU.
Today, Hexa butyl distannoxane is mainly used in wood preservation.

Hexa butyl distannoxane, or, more formally, bis(tri-1-butyltin) oxide, is a rather nasty substance and a potent biocide.
Like most volatile organotin compounds, Hexa butyl distannoxane can cause ill effects ranging from skin irritation to convulsions.

Hexa butyl distannoxane main use is as a wood preservative.
Hexa butyl distannoxane was formerly used as a marine anti-biofouling agent, but evidence of toxicity to marine animals led to a worldwide ban by the International Maritime Organization.
Other pesticide uses of Hexa butyl distannoxane have also been discontinued.

Hexa butyl distannoxane appears as thin, colourless to pale yellow, flammable and combustible liquid.
Hexa butyl distannoxane is soluble in organic solvents.

Hexa butyl distannoxane, or bis(tri-n-butyltin)oxide, is an organotin compound used as a biocide, fungicide, and molluscicide.
Hexa butyl distannoxane is uses of tributyltin also include as an anti-fouling chemical in marine paints for boats, anti-fungal agent in textiles and industrial water systems, in cooling tower and refrigeration water systems, wood pulp preservative in paints and paper mill systems, inner surfaces of cardboard, and in the manufacturing processes of leather goods, textiles, wood, plastics, and mothproof stored garments.
In fact, TBT compounds are considered the most hazardous of all tin compounds.

Hexa butyl distannoxane is an organotin compound used as a fungicide and molluscicide, particularly in wood preservation.
Hexa butyl distannoxane was used as an active component in marine antifouling paints but is not longer used due to Hexa butyl distannoxane toxicity and is considered a severe marine pollutant.

Hexa butyl distannoxane is widely used in Europe for the preservation of timber, millwork, and wood joinery, eg, window sashes and door frames.
Hexa butyl distannoxane is applied from organic solution by dipping or vacuum impregnation.

Hexa butyl distannoxane imparts resistance to attack by fungi and insects but is not suitable for underground use.
An advantage of Hexa butyl distannoxane is that Hexa butyl distannoxane does not interfere with subsequent painting or decorative staining and does not change the natural color of the wood.

Hexa butyl distannoxane is an organotin compound chiefly used as a biocide (fungicide and molluscicide), especially a wood preservative.
Hexa butyl distannoxane has the form of a colorless to pale yellow liquid that is only slightly soluble in water (20 ppm) but highly soluble in organic solvents.

Hexa butyl distannoxane is a potent skin irritant. Tributyltin compounds had been used as marine anti-biofouling agents.
Concerns over toxicity of these compounds have led to a worldwide ban by the International Maritime Organization.
Hexa butyl distannoxane is now considered a severe marine pollutant and a Substance of Very High Concern by the EU.

Hexa butyl distannoxane is used as an antifouling and biocide agent against fungi, algae and bacteria in paints and is an irritant.
Hexa butyl distannoxane is a chemical compound that the organometallic compounds belongs and primarily as underwater paint ( fungicide ) was used in shipbuilding.

Hexa butyl distannoxane is an organotin compound.
Tributyltins are the main active ingredients in certain biocides used to control a broad spectrum of organisms, and are also used in wood preservation, marine paints (as antifouling pesticides), and textiles and industrial water systems (as antifungal agents).
They also considered moderately to highly persistent organic pollutants and are especially hazardous to marine ecosystems.

The main toxic component of tributyltins is tin.
Tin is a chemical element with the symbol Sn and atomic number 50.
Hexa butyl distannoxane is a natural component of the earth's crust and is obtained chiefly from the mineral cassiterite, where Hexa butyl distannoxane occurs as tin dioxide

Hexa butyl distannoxane is employed in the synthesis of α,β-unsaturated methyl ketones, isoxazoles.

Hexa butyl distannoxane, or bis(tri-n-butyltin)oxide, is an organotin compound chiefly used as a biocide (fungicide and molluscicide), especially a wood preservative.
Hexa butyl distannoxane chemical formula is C24H54OSn2.

Hexa butyl distannoxane has the form of a thin, colorless to pale yellow liquid with melting point -45 °C, boiling point 180 °C, and slight water solubility (20 ppm).
Hexa butyl distannoxane is combustible and soluble in organic solvents.

Hexa butyl distannoxane is available under names AW 75-D, Bio-Met TBTO, Biomet, Biomet 75, BTO, Butinox, C-SN-9, Hexa butyl distannoxane, Hexabutylditin, and others.

Hexa butyl distannoxane is a potent skin irritant.
Tributyltin compounds had been used as marine anti-biofouling agents.

Concerns over toxicity of these compounds (some reports describe biological effects to marine life at a concentration of 1 nanogram per liter) have led to a world-wide ban by the International Maritime Organization.
Hexa butyl distannoxane is now considered a severe marine pollutant.

Tributyltin (TBT) compounds are organic derivatives of tetravalent tin.
They are characterized by the presence of covalent bonds between carbon atoms and a tin atom and have the general formula (n-C4H9)3Sn-X (where X isan anion).

The purity of commercial Hexa butyl distannoxane is generally above 96%; the principal impurities are dibutyltin derivatives and, to a lesser extent, tetrabutyltin and other trialkyltin compounds.
Hexa butyl distannoxane is a colourless liquid with a characteristic odour and a relative density of 1.17 to 1.18.

Hexa butyl distannoxane has been used as an anti-fouling paint on commercial ships for decades, inhibiting mollusks or barnacles from attaching themselves to ships.
However, Hexa butyl distannoxane has also been recognized as a toxic chemical that causes reproductive defects in and death of crustaceans.
Hexa butyl distannoxane is a common problem on both coasts of North America, and is a growing concern in the great lakes.

Uses of Hexa butyl distannoxane:
General formulation products used for home maintenance, which do not fit into a more refined category
Liquid or gels designed to seal cracks or fill cracks and depressions on hard surfaces
Algaecidal products for pools, hot tubs, and spas

Hexa butyl distannoxane is used as antimicrobial and slimicide for cooling-water treatment, disinfectant for hard-surface, sanitizer for laundry, mildewcides in water-based emulsion paints, preservative for timber, millwork, wood, textiles, paper, leather, and glass, and as fungicide and bactericide in underwater and antifouling paints;
Also used as pesticide, molluscicide, rodent repellant, and insecticide; Hexa butyl distannoxane is used as a bactericide, fungicide, and chemical intermediate;

Hexa butyl distannoxane is used as fungicide, disinfectant, algicide, microbiocide, and microbiostat for cooling tower water, wood preservation (paints, stains, and waterproofing formulations), hard surfaces (livestock, veterinary, and other animal facilities), building materials (drywall, joint compound MDF board, and particulate board), building material adhesives, and adhesives for other manufacturing applications;
Also used to treat textile fabrics (except laundry and clothing), paper, fiberfill, foam, rope, sponges, and other materials;
Tributyltin products are also used in petrochemical injection fluids, metal working fluids, irrigation tubing for non-agricultural uses, rubber for sonar domes, and instruments for oceanographic observations.

Industrial Processes with risk of exposure:
Pulp and Paper Processing
Textiles (Fiber & Fabric Manufacturing)
Painting (Pigments, Binders, and Biocides)
Applying Wood Preservatives
Using Disinfectants or Biocides

General Manufacturing Information of Hexa butyl distannoxane:
Tributyltin antifouling paint can be classified into three chemical groups based on the way the tributyltin is incorporated into the paint coating and subsequently released.
The first group includes paints in which the tributyltin active ingredient is mixed into the paint matrix and the tributyltin ion is released from the paint by diffusion.

These are called free association paints.
The second group has the tributyltin moiety chemically bound to the paint matrix.

These paints are called copolymer paints and under slightly alkaline conditions (such as sea water), the tributyltin ion is released by chemical hydrolysis.
Because the paint surface is softened by the loss of the tributyltin moiety, the outer layer is exposed.

A third category, tributyltin ablative paints, have characteristics of both groups.
The tributyltin active ingredient is mixed into the paint matrix, but because these are relatively soft paints, the surface ablates or sloughs off as the painted vessel moves through the water.

The use of tributyltin compounds in antifoulants are restricted because of their toxicity to aquatic organisms and EPA is cooperating in international efforts for a global phase-out.

Pharmacology and Biochemistry of Hexa butyl distannoxane:

MeSH Pharmacological Classification:

Disinfectants:
Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity.
Disinfectants are classed as complete, destroying spores as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms.
They are distinguished from antiseptics which are local anti-infective agents used on humans and other animals.

Fungicides, Industrial of Hexa butyl distannoxane:
Chemicals that kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc.

Immunosuppressive Agents of Hexa butyl distannoxane:
Agents that suppress immune function by one of several mechanisms of action.
Classical cytotoxic immunosuppressants act by inhibiting dna synthesis.

Others may act through activation of t-cells or by inhibiting the activation of helper cells.
While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of interleukins and other cytokines are emerging.

Absorption, Distribution and Excretion of Hexa butyl distannoxane:
Hexa butyl distannoxane is absorbed from the gut (20-50%, depending on the vehicle) & via the skin of mammals (approx 10%).
Other data suggest absorption in the 1-5% range via the skin.

Hexa butyl distannoxane can be transferred across the blood-brain barrier & from the placenta to the fetus.
Absorbed material is rapidly & widely distributed among tissues (principally the liver and kidney).

The rate of Hexa butyl distannoxane loss differs with different tissues.
Hexa butyl distannoxane & its metabolites are eliminated principally via the bile.

Reactivity Profile of Hexa butyl distannoxane:
Hexa butyl distannoxane may react vigorously with oxidizing agents and with reducing agents.

Handling and Storage of Hexa butyl distannoxane:

SMALL SPILLS AND LEAKAGE:
If you should spill this chemical, use absorbent paper to pick up all liquid spill material.
Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal.

Solvent wash all contaminated surfaces with acetone followed by washing with a strong soap and water solution.
Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS:
You should store this material in a refrigerator.

Safe Storage of Hexa butyl distannoxane:
Provision to contain effluent from fire extinguishing.
Store in an area without drain or sewer access.

Corneal edema induced by tributyltin) oxide:
Comeal edema induced by bis (tributyltin) oxide was studied with an electron microscope and the accumulation sites of tin were determined with an X-ray microanalyzer.
Male Wistar rats received an intramuscular injection of 0.5 ml/kg Hexa butyl distannoxane.

After time intervals of 2,4, 6, 8, 10, 12 h after injection, corneas were isolated and provided for electron microscopy.
Corneas from untreated rats served as controls.

Marked swelling of mitochondria in the corneal endothelial cells occurred at 4 h after Hexa butyl distannoxane injection.
The corneal edema appeared in the endothelial layer and the stroma at 6 h after injection.

By X-ray microanalysis, Sn peaks were obtained from swollen mitochondria in the endothelial cells.
At 12 h after Hexa butyl distannoxane injection, edematous swelling of the corneal tissue became more advanced.

These results indicated that parenterally administered Hexa butyl distannoxane accumulated in the mitochondria of corneal endothelial cells.
The direct toxic effects of Hexa butyl distannoxane on the mitochondria might cause the interference with active pump function of endothelial cells and induced the corneal edema.

First Aid of Hexa butyl distannoxane:

EYES:
First check the victim for contact lenses and remove if present.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN:
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing.
Gently wash all affected skin areas thoroughly with soap and water.

IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop.
IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop.

Provide proper respiratory protection to rescuers entering an unknown atmosphere.
Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION:
Some heavy metals are VERY TOXIC POISONS, especially if their salts are very soluble in water (e.g., lead, chromium, mercury, bismuth, osmium, and arsenic).
IMMEDIATELY call a hospital or poison control center and locate activated charcoal, egg whites, or milk in case the medical advisor recommends administering one of them.

Also locate Ipecac syrup or a glass of salt water in case the medical advisor recommends inducing vomiting.
Usually, this is NOT RECOMMENDED outside of a physician's care.

If advice from a physician is not readily available and the victim is conscious and not convulsing, give the victim a glass of activated charcoal slurry in water or, if this is not available, a glass of milk, or beaten egg whites and IMMEDIATELY transport victim to a hospital.
If the victim is convulsing or unconscious, do not give anything by mouth, assure that the victim's airway is open and lay the victim on his/her side with the head lower than the body.

DO NOT INDUCE VOMITING.
IMMEDIATELY transport the victim to a hospital.

Fire Fighting of Hexa butyl distannoxane:
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

Isolation and Evacuation of Hexa butyl distannoxane:
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL:
Increase, in the downwind direction, as necessary, the isolation distance shown above.

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Spillage Disposal of Hexa butyl distannoxane:
Personal protection: chemical protection suit including self-contained breathing apparatus.
Do NOT let this chemical enter the environment.

Carefully collect remainder.
Then store and dispose of according to local regulations.
Do NOT wash away into sewer.

Cleanup Methods of Hexa butyl distannoxane:
Do NOT wash away into sewer.
Carefully collect remainder, then remove to safe place.
Do NOT let this chemical enter the environment.

Disposal Methods of Hexa butyl distannoxane:
At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision.
Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Preventive Measures of Hexa butyl distannoxane:
Employees who handle bis(tri-n-butyltin)oxide should wash their hands thoroughly with soap or mild detergent & water before eating, smoking, or using toilet facilities.

If bis(tri-n-butyltin)oxide gets on the skin, immediately flush with large amounts of water, then wash with soap or mild detergent & water.
If bis(tri-n-butyltin)oxide soaks through the clothing, remove the clothing immediately & flush with large amounts of water & then wash using soap or mild detergent & water.
Get medical attention immediately.

Eating & smoking should not be permitted in areas where bis(tri-n-butyltin)oxide is handled, processed, or stored.

The scientific literature for the use of contact lenses in industry is conflicting.
The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses.

However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye.
In those specific cases, contact lenses should not be worn.
In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Identifiers of Hexa butyl distannoxane:
CAS Number: 56-35-9
ChEBI: CHEBI:81543
ChEMBL: ChEMBL511667
ChemSpider: 10218152
ECHA InfoCard: 100.000.244
EC Number: 200-268-0
KEGG: C18149
PubChem CID: 16682746
RTECS number: JN8750000
UNII: 3353Q84MKM
UN number: 2788 3020 2902
CompTox Dashboard (EPA): DTXSID9020166
InChI:
InChI=1S/6C4H9.O.2Sn/c6*1-3-4-2;;;/h6*1,3-4H2,2H3;;;
Key: APQHKWPGGHMYKJ-UHFFFAOYSA-N
InChI=1/6C4H9.O.2Sn/c6*1-3-4-2;;;/h6*1,3-4H2,2H3;;;/rC24H54OSn2/c1-7-13-19-26(20-14-8-2,21-15-9-3)25-27(22-16-10-4,23-17-11-5)24-18-12-6/h7-24H2,1-6H3
Key: APQHKWPGGHMYKJ-XAMPVVILAF
SMILES: CCCC[Sn](CCCC)(CCCC)O[Sn](CCCC)(CCCC)CCCC

Properties of Hexa butyl distannoxane:
Chemical formula: C24H54OSn2
Molar mass: 596.112
Appearance: colorless oil
Density: 1.17 g/mL at 25 °C (lit.)
Melting point: −45 °C (−49 °F; 228 K)
Boiling point: 180 °C (356 °F; 453 K) at 2 mm Hg
Solubility in water: 20 mg/L
Solubility: Hydrocarbons, alcohols, ethers, THF
log P: 5.02

Quality Level: 200
Vapor pressure: Assay: 96%
Form: liquid
Refractive index: n20/D 1.486 (lit.)
bp: 180 °C/2 mmHg (lit.)
Density: 1.17 g/mL at 25 °C (lit.)
SMILES string: CCCC[Sn](CCCC)(CCCC)O[Sn](CCCC)(CCCC)CCCC
InChI: 1S/6C4H9.O.2Sn/c6*1-3-4-2;;;/h6*1,3-4H2,2H3;;;
InChI key: APQHKWPGGHMYKJ-UHFFFAOYSA-N

Molecular Weight: 596.1
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 20
Exact Mass: 596.22128
Monoisotopic Mass: 598.22187
Topological Polar Surface Area: 9.2 Ų
Heavy Atom Count: 27
Formal Charge: 0
Complexity: 246
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Names of Hexa butyl distannoxane:

Preferred IUPAC name:
Hexa butyl distannoxane

Other names:
Bis(tributyltin) oxide
tri-n-butyltin oxide
bis(tri-n-butyltin)oxide
AW 75-D
Bio-Met TBTO
Biomet
Biomet 75
BTO
Butinox
C-SN-9
Hexadecanedioic Acid
HEXADECENE, N° CAS : 26952-14-7. Nom INCI : HEXADECENE, Nom chimique : 1-Hexadecene. N° EINECS/ELINCS : 248-131-4. Ses fonctions (INCI) : Solvant : Dissout d'autres substances
HEXADECYL HEXADECANOATE (CETYL PALMITATE)
Hexadecyl hexadecanoate, commonly known as Cetyl Palmitate, is an organic compound belonging to the class of fatty acid esters.
Its chemical formula is C32H64O2.
Hexadecyl hexadecanoate (Cetyl Palmitate) is derived from cetyl alcohol and palmitic acid.
Hexadecyl hexadecanoate (Cetyl Palmitate) is a waxy solid at room temperature and appears as a white to light yellowish substance.

CAS Number: 540-10-3
EC Number: 208-819-8

Cetyl Palmitate, Hexadecyl Palmitate, Palmitic Acid Cetyl Ester, Palmitoyl Cetyl Alcohol, Cetyl Ester of Palmitic Acid, C16-18 Diester of Hexadecyl Alcohol and Hexadecanoic Acid, Palmitic Acid, Hexadecyl Ester, 1-Hexadecanol, Hexadecyl Ester, Cetyl Hexadecanoate, Palmitic Acid C16-C18 Ester, Cetyl Hexadecanoate, N-Hexadecyl Palmitamide, Hexadecyl Palmitate NF, Cetyl Palmitate NF, Palmitic Acid, Cetyl Ester, Hexadecyl Ester of Palmitic Acid, Palmitic Acid Hexadecyl Ester, Cetyl Hexadecanoate NF, N-Hexadecyl Hexadecanoamide, Hexadecyl Palmitate (VAN), EINECS 208-819-8, UNII-2LMG2R6B6J, Cetyl Esters, Hexadecanoic Acid, Hexadecyl Ester, Cetylhexadecanoate, Cetyl Palmitate (VAN), Cetopalmitate, Cetyl Palmitate (VANDF), Hexadecanoic Acid, 1-Hexadecanol Ester, Hexadecyl Palmitate (2:1), NSC 32470, Hexadecyl Ester of Hexadecanoic Acid, Hexadecanoic Acid, Hexadecyl Ester, 1-Hexadecanol Hexadecanoate, Hexadecyl Ester of Palmitic Acid (8CI), Hexadecyl Hexadecanoate (8CI), Cetyl Hexadecanoate (NF), Hexadecanoic Acid Hexadecyl Ester (8CI), Palmitic Acid, Hexadecyl Ester (6CI,7CI,8CI), 1-Hexadecyl Hexadecanoate, Palmitic Acid, 1-Hexadecyl Ester, Hexadecyl Hexadecanoate (6CI,7CI), Palmitic Acid, Cetyl Ester (6CI,7CI), NSC 226088, BRN 1771521, DSSTox_CID_21171, SCHEMBL2258115



APPLICATIONS


Hexadecyl hexadecanoate (Cetyl Palmitate) is commonly used in skincare products such as creams, lotions, and moisturizers.
Hexadecyl hexadecanoate (Cetyl Palmitate) serves as an effective emollient, helping to soften and smooth the skin's surface.

Hexadecyl hexadecanoate (Cetyl Palmitate) enhances the spreadability of cosmetic formulations, ensuring even application.
Hexadecyl hexadecanoate (Cetyl Palmitate) is often included in sunscreen formulations for its moisturizing properties.

Hexadecyl hexadecanoate (Cetyl Palmitate) helps to improve the texture of skincare products, giving them a luxurious feel.
Cetyl Palmitate acts as a lubricant, reducing friction on the skin and preventing moisture loss.

Hexadecyl hexadecanoate (Cetyl Palmitate) is used in lip balms and lipsticks to provide a smooth, moisturizing texture.
Hexadecyl hexadecanoate (Cetyl Palmitate) is added to makeup products such as foundations and concealers to improve blendability.
Hexadecyl hexadecanoate (Cetyl Palmitate) is used in hair care products such as conditioners and styling creams to enhance manageability.

Hexadecyl hexadecanoate (Cetyl Palmitate) helps to reduce static and frizz in hair, leaving it smooth and shiny.
Hexadecyl hexadecanoate (Cetyl Palmitate) is included in bath oils and shower gels for its moisturizing and soothing properties.
Hexadecyl hexadecanoate (Cetyl Palmitate) is used in massage oils and body scrubs to provide a smooth glide and moisturizing effect.

Hexadecyl hexadecanoate (Cetyl Palmitate) is added to anti-aging creams and serums to hydrate and nourish the skin.
Hexadecyl hexadecanoate (Cetyl Palmitate) is included in baby lotions and diaper creams for its gentle and moisturizing properties.

Hexadecyl hexadecanoate (Cetyl Palmitate) is used in shaving creams and foams to provide a smooth shave and prevent irritation.
Hexadecyl hexadecanoate (Cetyl Palmitate) is added to deodorants and antiperspirants for its skin-conditioning properties.

Hexadecyl hexadecanoate (Cetyl Palmitate) is used in wound healing creams and ointments to soothe and protect the skin.
Hexadecyl hexadecanoate (Cetyl Palmitate) is included in foot creams and balms to soften and moisturize rough skin.
Hexadecyl hexadecanoate (Cetyl Palmitate) is used in hand creams and lotions to hydrate and protect the hands from dryness.

Hexadecyl hexadecanoate (Cetyl Palmitate) is added to bath bombs and bath salts for its moisturizing and emollient properties.
Hexadecyl hexadecanoate (Cetyl Palmitate) is used in fragrance formulations to enhance longevity and diffusion.
Hexadecyl hexadecanoate (Cetyl Palmitate) is included in self-tanning products to improve spreadability and evenness of application.

Hexadecyl hexadecanoate (Cetyl Palmitate) is added to acne treatments and spot treatments for its moisturizing and soothing effects.
Hexadecyl hexadecanoate (Cetyl Palmitate) is used in nail treatments and cuticle creams to soften and moisturize the nails and cuticles.
Overall, Cetyl Palmitate finds applications in a wide range of skincare, hair care, and cosmetic products, contributing to their effectiveness and sensory appeal.

Hexadecyl hexadecanoate (Cetyl Palmitate) is added to facial cleansers and makeup removers to help dissolve and lift away impurities.
Hexadecyl hexadecanoate (Cetyl Palmitate) is used in hand sanitizers and antibacterial gels for its moisturizing and skin-conditioning properties.

Hexadecyl hexadecanoate (Cetyl Palmitate) is included in exfoliating scrubs and peels to help remove dead skin cells and reveal smoother skin.
Hexadecyl hexadecanoate (Cetyl Palmitate) is added to night creams and overnight masks to provide deep hydration and nourishment.

Hexadecyl hexadecanoate (Cetyl Palmitate) is used in foot scrubs and callus removers to soften and smooth rough areas of the feet.
Hexadecyl hexadecanoate (Cetyl Palmitate) is added to cuticle oils and treatments to moisturize and condition the nails and surrounding skin.
Hexadecyl hexadecanoate (Cetyl Palmitate) is included in hair masks and deep conditioning treatments to soften and nourish dry, damaged hair.

Hexadecyl hexadecanoate (Cetyl Palmitate) is used in massage candles and wax melts for its skin-conditioning and aromatherapy benefits.
Hexadecyl hexadecanoate (Cetyl Palmitate) is added to body sprays and mists to provide a light, refreshing scent.

Hexadecyl hexadecanoate (Cetyl Palmitate) is used in foot powders and sprays to absorb moisture and prevent odor.
Hexadecyl hexadecanoate (Cetyl Palmitate) is included in intimate lubricants and gels for its smooth and non-irritating texture.

Hexadecyl hexadecanoate (Cetyl Palmitate) is used in cuticle removers and softeners to gently exfoliate and remove excess cuticle.
Hexadecyl hexadecanoate (Cetyl Palmitate) is added to hair serums and oils to tame frizz and add shine.

Hexadecyl hexadecanoate (Cetyl Palmitate) is included in facial serums and treatments for its skin-conditioning and anti-aging properties.
Hexadecyl hexadecanoate (Cetyl Palmitate) is used in body washes and shower gels to provide a creamy lather and moisturizing effect.

Hexadecyl hexadecanoate (Cetyl Palmitate) is added to facial masks and treatments to enhance their moisturizing and soothing benefits.
Hexadecyl hexadecanoate (Cetyl Palmitate) is used in lip scrubs and exfoliators to remove dry, flaky skin and soften the lips.

Hexadecyl hexadecanoate (Cetyl Palmitate) is included in eye creams and serums to hydrate and reduce the appearance of fine lines and wrinkles.
Hexadecyl hexadecanoate (Cetyl Palmitate) is added to hair styling creams and gels to provide hold and texture.

Hexadecyl hexadecanoate (Cetyl Palmitate) is used in aftersun lotions and gels to soothe and hydrate sun-exposed skin.
Hexadecyl hexadecanoate (Cetyl Palmitate) is included in body butters and balms for its rich, nourishing texture.
Hexadecyl hexadecanoate (Cetyl Palmitate) is added to scalp treatments and oils to moisturize and soothe dry, itchy scalp.

Hexadecyl hexadecanoate (Cetyl Palmitate) is used in nail polishes and treatments to condition and strengthen the nails.
Hexadecyl hexadecanoate (Cetyl Palmitate) is included in anti-cellulite creams and treatments for its skin-smoothing properties.
Hexadecyl hexadecanoate (Cetyl Palmitate) finds applications in a wide range of cosmetic and personal care products, contributing to their efficacy and sensory experience.



DESCRIPTION


Hexadecyl hexadecanoate, commonly known as Cetyl Palmitate, is an organic compound belonging to the class of fatty acid esters.
Its chemical formula is C32H64O2.
Hexadecyl hexadecanoate (Cetyl Palmitate) is derived from cetyl alcohol and palmitic acid.
Hexadecyl hexadecanoate (Cetyl Palmitate) is a waxy solid at room temperature and appears as a white to light yellowish substance.

Hexadecyl hexadecanoate (Cetyl Palmitate) is widely used in cosmetics, skincare products, and pharmaceutical formulations due to its emollient properties.
Hexadecyl hexadecanoate (Cetyl Palmitate) acts as a lubricant on the skin's surface, giving it a soft and smooth feel.
Additionally, Cetyl Palmitate helps to retain moisture, making it beneficial for dry or sensitive skin.

Hexadecyl hexadecanoate, commonly known as Cetyl Palmitate, is a waxy solid at room temperature.
Hexadecyl hexadecanoate (Cetyl Palmitate) appears as a white to light yellowish substance with a smooth texture.

Hexadecyl hexadecanoate (Cetyl Palmitate) is odorless and has a faint characteristic odor.
Hexadecyl hexadecanoate (Cetyl Palmitate) is derived from cetyl alcohol and palmitic acid through esterification.

Hexadecyl hexadecanoate (Cetyl Palmitate) has a chemical formula of C32H64O2 and a molecular weight of approximately 480.85 g/mol.
Hexadecyl hexadecanoate (Cetyl Palmitate) is insoluble in water but soluble in organic solvents such as ethanol and acetone.

Hexadecyl hexadecanoate (Cetyl Palmitate) has a melting point ranging from approximately 50°C to 60°C.
Hexadecyl hexadecanoate (Cetyl Palmitate) exhibits low volatility and a low vapor pressure.
Hexadecyl hexadecanoate (Cetyl Palmitate) is commonly used in cosmetics and skincare products for its emollient properties.

Hexadecyl hexadecanoate (Cetyl Palmitate) acts as a lubricant on the skin's surface, providing a smooth and soft texture.
Hexadecyl hexadecanoate (Cetyl Palmitate) helps to retain moisture, making it beneficial for dry or sensitive skin types.

Hexadecyl hexadecanoate (Cetyl Palmitate) is often included in creams, lotions, lip balms, and makeup products.
Hexadecyl hexadecanoate (Cetyl Palmitate) contributes to the spreadability and texture of these formulations, enhancing their sensory appeal.

Hexadecyl hexadecanoate (Cetyl Palmitate) is also used in pharmaceutical formulations as an excipient in topical creams and ointments.
Hexadecyl hexadecanoate (Cetyl Palmitate) improves the consistency and stability of these formulations while enhancing their moisturizing properties.

Hexadecyl hexadecanoate (Cetyl Palmitate) is gentle on the skin and suitable for use in a variety of cosmetic and skincare products.
Hexadecyl hexadecanoate (Cetyl Palmitate) is non-comedogenic and does not clog pores, making it suitable for acne-prone skin.
Hexadecyl hexadecanoate (Cetyl Palmitate) has been shown to have skin-conditioning and soothing properties.

Hexadecyl hexadecanoate (Cetyl Palmitate) is compatible with a wide range of cosmetic ingredients and formulations.
Hexadecyl hexadecanoate (Cetyl Palmitate) is stable under normal storage conditions and has a long shelf life.

Hexadecyl hexadecanoate (Cetyl Palmitate) is regulated for use in cosmetics and personal care products by various regulatory agencies.
Hexadecyl hexadecanoate (Cetyl Palmitate) undergoes rigorous testing to ensure its safety and efficacy in consumer products.

Hexadecyl hexadecanoate (Cetyl Palmitate) is widely used in the cosmetic industry for its versatility and effectiveness as an emollient.
Hexadecyl hexadecanoate (Cetyl Palmitate) contributes to the luxurious feel and performance of many skincare and cosmetic formulations.
Overall, Hexadecyl hexadecanoate (Cetyl Palmitate) is valued for its skin-conditioning properties and its ability to enhance the texture and spreadability of cosmetic products.



PROPERTIES


Physical Properties:

Appearance: White to light yellowish waxy solid
Texture: Smooth and creamy
Odor: Faint characteristic odor
Melting Point: Typically ranges from 50°C to 60°C
Boiling Point: Decomposes before boiling
Solubility: Insoluble in water; soluble in organic solvents such as ethanol, acetone, and ether
Density: Approximately 0.8 to 0.9 g/cm³
Viscosity: Varies depending on temperature and formulation
Refractive Index: Typically around 1.45 to 1.47


Chemical Properties:

Chemical Formula: C32H64O2
Molecular Weight: Approximately 480.85 g/mol
Chemical Structure: Ester formed from cetyl alcohol (hexadecanol) and palmitic acid
Hydrophilic-Lipophilic Balance (HLB): Low HLB value, indicating lipophilic nature
pH: Neutral



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
Assist the person in finding a comfortable position to sit or lie down.
If breathing is difficult, provide oxygen if available and seek medical attention promptly.
Keep the affected person warm and at rest.
If breathing has stopped, provide artificial respiration immediately.


Skin Contact:

Remove contaminated clothing and shoes immediately, taking care not to spread the substance further.
Wash the affected skin area thoroughly with mild soap and lukewarm water for at least 15 minutes to remove any residual substance.
Avoid scrubbing the skin vigorously, as this may exacerbate irritation.
If irritation persists or develops, seek medical advice promptly.
Apply a soothing and hydrating cream or lotion to the affected area to alleviate discomfort and prevent dryness.


Eye Contact:

Flush the eyes gently with lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Seek immediate medical attention, even if irritation or discomfort is minimal.
Remove contact lenses, if present and easily removable, after flushing the eyes.
Avoid rubbing the eyes, as this may cause further irritation.
Continue rinsing the eyes with water until medical help arrives.


Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth thoroughly with water, but do not swallow.
Offer sips of water to drink if the person is conscious and able to swallow.
Seek immediate medical attention or contact a poison control center.
Do not administer anything by mouth to an unconscious person.



HANDLING AND STORAGE


Handling:

Wear appropriate personal protective equipment (PPE) such as safety glasses, gloves, and protective clothing when handling Hexadecyl hexadecanoate.
Avoid inhalation of dust, vapors, or aerosols.
Use local exhaust ventilation if necessary to minimize exposure.
Use in a well-ventilated area to prevent the buildup of vapors.

Ensure adequate ventilation in confined spaces.
Avoid contact with skin and eyes.
In case of skin contact, wash affected area with soap and water.
In case of eye contact, rinse eyes thoroughly with water for several minutes and seek medical attention if irritation persists.

Do not eat, drink, or smoke while handling Hexadecyl hexadecanoate.
Wash hands thoroughly after handling.
Use appropriate handling equipment such as pumps, dispensers, or scoops to transfer the substance and minimize spills or splashes.

Avoid generating dust or aerosols.
Handle the substance carefully to prevent dispersion into the air.
Store containers of Hexadecyl hexadecanoate tightly closed when not in use to prevent contamination and minimize evaporation.

Keep away from heat sources, sparks, open flames, and ignition sources to prevent fire or explosion hazards.
Avoid contact with incompatible materials such as strong oxidizing agents, acids, or alkalis. Store separately from these materials.


Storage:

Store Hexadecyl hexadecanoate in a cool, dry, well-ventilated area away from direct sunlight and sources of heat.
Keep containers tightly closed and upright to prevent leakage and spills.

Ensure containers are properly labeled with appropriate hazard warnings.
Store away from food, beverages, and animal feed to prevent contamination.
Do not store near strong oxidizing agents, acids, or alkalis.

Keep away from incompatible materials to prevent reactions.
Store in containers made of compatible materials such as high-density polyethylene (HDPE) or stainless steel.
Ensure storage area is equipped with suitable fire detection and suppression systems.

Check containers regularly for signs of damage or deterioration.
Replace damaged containers promptly.
Store in a designated area with appropriate containment measures to prevent environmental contamination in case of spills or leaks.

Follow all local regulations and guidelines for the storage of hazardous chemicals.
Keep storage area clean, dry, and well-organized to facilitate safe handling and access.
HEXAFLUOROSILICIC ACID
Hexagluorosilicic Acid; Hexafluorosilicic Acid; Hydrofluorosilicic Acid; Hydrosilicofluoric acid; Sand acid; Silicofluoric acid; Fluosilicic acid; Hydrofluorosilicic acid; Hydrofluosilic Acid; Hexafluorosilicic acid; Dihydrogen hexafluorosilicate; cas no: 16961-83-4
HEXAFLUOROSILICIC ACID
Hexafluorosilicic Acid is an inorganic compound with the chemical formula H2SiF6.
Aqueous solutions of Hexafluorosilicic Acid consist of salts of the cation and hexafluorosilicate anion.


CAS Number: 16961-83-4
EC-Number: 241-034-8
MDL number: MFCD00036289
Molecular Formula: H2SiF6 / F6H2Si / H2F6Si


Hexafluorosilicic Acid appears as a colorless fuming liquid with a penetrating pungent odor.
Hexafluorosilicic Acid is the basic raw material for the preparation of sodium fluorosilicate, potassium, ammonium, magnesium, copper, barium, lead and other fluorosilicates and silicon tetrafluoride.


Hexafluorosilicic Acid,H2SiF6, also known as hydrofluorosilicic acid,is a colorless liquid that is soluble in water.
Hexafluorosilicic Acid is highly corrosive and toxic,attacking glass and stoneware.
Hexafluorosilicic Acid is used in water fluoridation, electroplating, and in manufacturing enamels and cement.


Hexafluorosilicic Acid is a transparent, colorless fuming liquid.
Hexafluorosilicic acid is a kind of inorganic acid.
Hexafluorosilicic Acid is a kind of inorganic acid.


Hexafluorosilicic Acid is majorly used for the fluoridation of water in United State to minimize the incidence of dental caries and dental fluorosis.
For chemical synthesis, Hexafluorosilicic Acid is majorly used for the manufacturing of aluminum fluoride and cryolite as well as many kinds of hexafluorosilicate salts.


Hexafluorosilicic Acid can also be used for the production of silicon and silicon dioxide.
Hexafluorosilicic Acid can also be used as an electrolyte in the Betts electrolytic process for refining lead.
Hexafluorosilicic Acid is also a specialized reagent in organic synthesis for cleaving Si–O bonds of silyl ethers.


Hexafluorosilicic Acid is s colorless fuming liquid with a penetrating pungent odor.
Hexafluorosilicic Acid is corrosive to metals and tissue.
Both the fumes and very short contact with the liquid can cause severe and painful burns.


Hexafluorosilicic Acid is produced naturally on a large scale in volcanoes.
Hexafluorosilicic Acid is manufactured as a coproduct in the production of phosphate fertilizers.
The resulting Hexafluorosilicic Acid is almost exclusively consumed as a precursor to aluminum trifluoride and synthetic cryolite, which are used in aluminium processing.


Salts derived from Hexafluorosilicic Acid are called hexafluorosilicates.
Hexafluorosilicic Acid is miscible with water.
Hexafluorosilicic Acid is incompatible in strong oxidizing agents, metals, alkalis, strong acids, stoneware and glass.


Hexafluorosilicic Acid is a colorless liquid with a sour, pungent odor; [HSDB] Aqueous solution (<=35% fluorosilicic acid).
Hexafluorosilicic Acid is clear light yellow liquid.
Hexafluorosilicic Acid is an inorganic compound with the chemical formula H2SiF6.


Aqueous solutions of Hexafluorosilicic Acid consist of salts of the cation and hexafluorosilicate anion.
These salts and their aqueous solutions are colorless.
Hexafluorosilicic acid is produced naturally on a large scale in volcanoes.


Hexafluorosilicic Acid is manufactured as a coproduct in the production of phosphate fertilizers.
The resulting Hexafluorosilicic Acid is almost exclusively consumed as a precursor to aluminum trifluoride and synthetic cryolite, which are used in aluminium processing.


Salts derived from Hexafluorosilicic Acid are called hexafluorosilicates.
Hexafluorosilicic Acid is a water insoluble Silicon source for use in oxygen-sensitive applications, such as metal production.
In extremely low concentrations (ppm), fluoride compounds are used in health applications.


Fluoride compounds also have significant uses in synthetic organic chemistry.
They are commonly also used to alloy metal and for optical deposition.
Certain fluoride compounds can be produced at nanoscale and in ultra high purity forms.


Hexafluorosilicic Acid is generally immediately available in most volumes.
Ultra high purity and high purity compositions improve both optical quality and usefulness as scientific standards.
Nanoscale elemental powders and suspensions, as alternative high surface area forms, may be considered.


Hexafluorosilicic Acid is the increasing use of it in textile industries due to its stain and smudge removing properties.
Hexafluorosilicic Acid is a chemical that can be used for the treatment of water.
Hexafluorosilicic Acid is typically used when there is too much fluoride in the water.


Hexafluorosilicic Acid reacts with the fluoride ion to form hexafluorosilicate, which precipitates out of solution.
This process removes 75% of the fluoride from the water in an hour. Hexafluorosilicic Acid also has been shown to be effective against sulfa drugs and phosphorus pentoxide, making it useful for wastewater treatment as well as analytical chemistry.


The chemical stability and reaction mechanism of Hexafluorosilicic Acid makes it a good choice for use in industry.
Hexafluorosilicic Acid is a colorless, fuming liquid and is the most commonly used fluoridation methods for treating drinking water.
Hexafluorosilicic Acid contains 34% hexafluorosilicic acid and 65% water.


Hexafluorosilicic Acid is a colorless liquid with a stinging odor.
Hexafluorosilicic acid is completely miscible in water and stable under normal conditions.
Hexafluorosilicic Acid, also known as hydrofluorosilicic acid or fluorosilicic acid, is a colorless liquid with the chemical formula H2SiF6.


Hexafluorosilicic Acid is primarily derived from the production of phosphate fertilizers or from the scrubbing of industrial gases.
Hexafluorosilicic acid is the chemical compound with the formula H2SiF6.
The free acid is encountered as an equilibrium mixture with hexaflurorosilicate anion (SiF62−) only in solution in solvents that are proton donors at low pH.


In aqueous solution, evaporation of H2SiF6 results in loss of HF and SiF4.
H2SiF6 is a by-product from the reaction of fluoroapatite with sulfuric acid, which produces HF, which in turn reacts with silicate minerals:
SiO2 + 6 HF → H2SiF6 + 2 H2O


Aqueous solutions of H2SiF6 contain the hexafluorosilicate anion, SiF62−.
In this octahedral anion, the Si-F bond distances are 1.71 Å.



USES and APPLICATIONS of HEXAFLUOROSILICIC ACID:
Hexafluorosilicic acid is used as a chemical intermediate, a disinfectant, a water fluoridating agent, a wood preservative, a masonry and ceramic hardener, and a glass additive.
Hexafluorosilicic Acid is also used to treat hides and skins, to electroplate chromium, and to electrolytically refine lead.


Further, Hexafluorosilicic Acid is used in technical paints, oil well acidizing, and to remove mold, rust, and stains from textiles or in biocidal products.
The majority of the Hexafluorosilicic Acid is converted to aluminium fluoride and synthetic cryolite.
These materials are central to the conversion of aluminium ore into aluminium metal.


The conversion to aluminium trifluoride is described as:
H2SiF6 + Al2O3 → 2 AlF3 + SiO2 + H2O
Hexafluorosilicic acid is also converted to a variety of useful hexafluorosilicate salts.


The potassium salt, Potassium fluorosilicate, is used in the production of porcelains, the magnesium salt for hardened concretes and as an insecticide, and the barium salts for phosphors.
Hexafluorosilicic acid and the salts are used as wood preservation agents.


Lead refining uses of Hexafluorosilicic Acid: Hexafluorosilicic acid is also used as an electrolyte in the Betts electrolytic process for refining lead.
Rust removers uses of Hexafluorosilicic Acid: Hexafluorosilicic acid (identified as hydrofluorosilicic acid on the label) along with oxalic acid are the active ingredients used in Iron Out rust-removing cleaning products, which are essentially varieties of laundry sour.


Hexafluorosilicic Acid is majorly used for the fluoridation of water in United State to minimize the incidence of dental care.
Hexafluorosilicic Acid is used for metal plating, wood anticorrosion, beer disinfection, brewing industrial equipment disinfection (1%~2% H2SiF6) and lead electrolytic refining.


Hexafluorosilicic Acid is used as mordant and metal surface treatment agent.
Hexafluorosilicic Acid is mainly produced as a precursor to aluminum trifluoride and synthetic cryolite.
Hexafluorosilicic Acid is commonly used as a source of fluoride for water fluoridation.


Hexafluorosilicic acid is also converted to a variety of useful hexafluorosilicate salts.
The potassium salt is used in the production of porcelains, the magnesium salt.
Hexafluorosilicic acid is mainly used in: Hexafluorosilicic Acid is used as the preparation of aluminium fluoride cryolite and sodium fluorosilicate.


Hexafluorosilicic Acid is used as an analytical reagent and also used in the synthesis of silicates.
Hexafluorosilicic Acid is used widely for sterilizing equipment in brewing and bottling establishments.
Other concentrations of Hexafluorosilicic Acid are used in the electrolytic refining of lead, in electroplating, for hardening cement, crumbling lime or brick work, for the removal of lime from hides during the tanning process, to remove molds, as preservative for timber.


Hexafluorosilicic Acid is used in water fluoridation, in hardening cement and ceramics, as a wood preservative.
Hexafluorosilicic Acid is used fluoride source with both protic and Lewis acid properties providing efficient cleavage of silicon–oxygen bonds, e.g. silyl ether deprotection.


Hexafluorosilicic Acid is commonly used as a source of fluoride.
Hexafluorosilicic Acid is converted to a variety of useful hexafluorosilicate salts.
Hexafluorosilicic Acid is also used as an electrolyte in the Betts electrolytic process for refining lead.


Hexafluorosilicic Acid is an important organic reagent for cleaving Si-O bonds of silyl ethers.
Further, Hexafluorosilicic Acid is used as wood a preservation agent and also used in surface modification of calcium carbonate.
Hexafluorosilicic Acid is used widely for sterilizing equipment in brewing and bottling establishments.


Other concentrations of Hexafluorosilicic Acid are used in the electrolytic refining of lead, in electroplating, for hardening cement, crumbling lime or brick work, for the removal of lime from hides during the tanning process, to remove molds, as preservative for timber.
Hexafluorosilicic Acid is used in water fluoridation, in hardening cement and ceramics, as a wood preservative.


Hexafluorosilicic Acid is used Water Fluoridation, Disinfecting Copper & Brass Vessels, Sterilizing Bottling & Brewing, Cement, Ceramics, and Wood Preservative.
Hexafluorosilicic acid is commonly used as a source of fluoride.


Hexafluorosilicic Acid is converted to a variety of useful hexafluorosilicate salts.
Hexafluorosilicic Acid is also used as an electrolyte in the Betts electrolytic process for refining lead.
Hexafluorosilicic Acid is an important organic reagent for cleaving Si-O bonds of silyl ethers.


Further, Hexafluorosilicic Acid is used as wood a preservation agent and also used in surface modification of calcium carbonate.
Hexafluorosilicic Acid is used as a chemical intermediate, a disinfectant, a water fluoridating agent, a wood preservative, a masonry and ceramic hardener, and a glass additive.


Hexafluorosilicic Acid is also used to treat hides and skins, to electroplate chromium, and to electrolytically refine lead.
Hexafluorosilicic Acid is used in technical paints, oil well acidizing, and to remove mold, rust, and stains from textiles.
Hexafluorosilicic Acid is commonly used as a source of fluoride.


Hexafluorosilicic Acid is converted to a variety of useful hexafluorosilicate salts.
Hexafluorosilicic Acid is also used as an electrolyte in the Betts electrolytic process for refining lead.
Hexafluorosilicic Acid is an important organic reagent for cleaving Si-O bonds of silyl ethers.


Further, Hexafluorosilicic Acid is used as wood a preservation agent and also used in surface modification of calcium carbonate.
Hexafluorosilicic Acid is mainly used in the production of fluorine silicate, silicon tetrafluoride, also used in electroplating, Wood corrosion, brewing industry equipment Disinfection, water additives


Hexafluorosilicic Acid is a highly corrosive and toxic substance that requires careful handling and proper dosing.
Hexafluorosilicic Acid is added to water treatment systems in controlled amounts to achieve the desired fluoride concentration, contributing to the prevention of tooth decay.


Hexafluorosilicic Acid is commonly used for water fluoridation in several countries including the United States, Great Britain, and Ireland.
Hexafluorosilicic Acid is a reagent in organic synthesis for cleaving Si-O bonds of silyl ethers.
Hexafluorosilicic Acid is more reactive for this purpose than HF.


Hexafluorosilicic Acid reacts faster with t-butyldimethysilyl (TBDMS) ethers than triisopropylsilyl (TIPS) ethers.
Hexafluorosilicic Acid and the salts are used as wood preservation agents.
The aluminium and magnesium hexafluorosilicate are two used compounds.


Hexafluorosilicic Acid is mainly used in the production of fluorosilicate, silicon tetrafluoride, also used in electroplating, wood corrosion, brewing industry equipment disinfection, water additives, etc.
Hexafluorosilicic Acid is commonly used in water fluoridation programs to increase the fluoride content of drinking water for dental health purposes.


-Niche applications of Hexafluorosilicic Acid:
Hexafluorosilicic Acid is a specialized reagent in organic synthesis for cleaving Si–O bonds of silyl ethers.
Hexafluorosilicic Acid is more reactive for this purpose than HF.
Hexafluorosilicic Acid reacts faster with t-butyldimethysilyl (TBDMS) ethers than triisopropylsilyl (TIPS) ethers.


-Treating concrete uses of Hexafluorosilicic Acid:
The application of hexafluorosilica acid to a calcium rich surface such as concrete will give that surface some resistance to acid attack.
CaCO3 + H2O → Ca2+ + 2 OH− + CO2
H2SiF6 → 2 H+ + SiF2−6SiF2−6 + 2 H2O → 6 F− + SiO2 + 4 H+
Ca2+ + 2 F− → CaF2
Calcium fluoride (CaF2) is an insoluble solid that is acid resistant.


-Natural salts uses of Hexafluorosilicic Acid:
Some rare minerals, encountered either within volcanic or coal-fire fumaroles, are salts of the hexafluorosilicic acid.
Examples include ammonium hexafluorosilicate that naturally occurs as two polymorphs: cryptohalite and bararite.


-Industrial uses of Hexafluorosilicic Acid:
Hexafluorosilicic Acid (H2SiF6) is a colorless to light brown liquid. It is also manufactured from calcium fluoride or other fluoride-containing products.
Hexafluorosilicic Acid is a strong depressant for many silicates during flotation of a number of oxidic minerals.
Hexafluorosilicic Acid is used for gangue depression during flotation of tin, columbite and tantalite.


-Hexafluorosilicic Acid Uses in Water Treatment:
Hexafluorosilicic Acid finds specific applications in water treatment processes, primarily in water fluoridation programs.
Hexafluorosilicic Acid is added to public water supplies with the aim of increasing the concentration of fluoride ions for dental health benefits.

By adjusting the fluoride content in drinking water, Hexafluorosilicic Acid helps prevent tooth decay and promote overall dental health.
Water fluoridation programs using Hexafluorosilicic Acid must follow strict guidelines and regulations to ensure proper dosing and safety.
The concentration of fluoride added to the water supply is carefully monitored to achieve an optimal balance between dental health benefits and potential risks.

Additionally, Hexafluorosilicic Acid can be used for pH adjustment in water treatment processes, contributing to the control and stabilization of water pH within the desired range.
Order Hexafluorosilicic Acid from Water Solutions Unlimited.



CHEMICAL PROPERTIES OF HEXAFLUOROSILICIC ACID:
Hexafluorosilicic Acid,H2SiF6, also known as hydrofluorosilicic acid,is a colorless liquid that is soluble in water.
Hexafluorosilicic Acid is highly corrosive and toxic,attacking glass and stoneware.
Hexafluorosilicic Acid is used in water fluoridation, electroplating, and in manufacturing enamels and cement.
Hexafluorosilicic Acid is a transparent, colorless fuming liquid.



USE AND MANUFACTURING OF HEXAFLUOROSILICIC ACID:
Silica powder acid hydrolysis method Hydrofluoric acid is first added to the lead-line acid hydrolysis equipment, and then the silica powder is gradually added to make it react.

After the reaction is complete, add rice bran ash to neutralize the free hydrofluoric acid, and at the same time act as a bleaching solution, filter the solution, and add an appropriate amount of Huangdan powder (PbO) to the filtrate to remove the hydrofluoric acid.
The sulphate which is added is then filtered to obtain the finished Hexafluorosilicic Acid product.
Its 6HF+SiO2→H2SiF6+2H2O



HEXAFLUOROSILICIC ACID'S GENERAL CHARACTERISTICS ARE:
*Chemical Formula:
H2SiF6
*Physical State:
Colorless liquid

*Source:
Hexafluorosilicic Acid is derived from phosphate fertilizer production or industrial gas scrubbing
*Water Fluoridation:
Hexafluorosilicic Acid is used in water treatment for dental health by increasing fluoride content in drinking water



STRUCTURE OF HEXAFLUOROSILICIC ACID:
Hexafluorosilicic Acid has been crystallized as various hydrates.
These include (H5O2)2SiF6, the more complicated (H5O2)2SiF6·2H2O, and (H5O2)(H7O3)SiF6·4.5H2O.
In all of these salts, the octahedral hexafluorosilicate anion is hydrogen bonded to the cations.
Aqueous solutions of Hexafluorosilicic Acid are often described as H
2SiF6.



PRODUCTION AND PRINCIPAL REACTIONS OF HEXAFLUOROSILICIC ACID:
Hexafluorosilicic acid is produced commercially from fluoride-containing minerals that also contain silicates.
Specifically, apatite and fluorapatite are treated with sulfuric acid to give phosphoric acid, a precursor to several water-soluble fertilizers.
This is called the wet phosphoric acid process.

As a by-product, approximately 50 kg of Hexafluorosilicic Acid is produced per tonne of HF owing to reactions involving silica-containing mineral impurities. 
Some of the hydrogen fluoride (HF) produced during this process in turn reacts with silicon dioxide (SiO2) impurities, which are unavoidable constituents of the mineral feedstock, to give silicon tetrafluoride.

Thus formed, the silicon tetrafluoride reacts further with HF.
The net process can be described as:
6 HF + SiO2 → SiF2−6 + 2 H3O+
Hexafluorosilicic acid can also be produced by treating silicon tetrafluoride with hydrofluoric acid.



REACTIONS OF HEXAFLUOROSILICIC ACID:
In water, Hexafluorosilicic Acid readily hydrolyzes to hydrofluoric acid and various forms of amorphous and hydrated silica ("SiO2").
At the concentration usually used for water fluoridation, 99% hydrolysis occurs and the pH drops.
The rate of hydrolysis increases with pH.

At the pH of drinking water, the degree of hydrolysis is essentially 100%.
H2SiF6 + 2 H2O → 6 HF + "SiO2"
Near neutral pH, hexafluorosilicate salts hydrolyze rapidly according to this equation:
SiF2−6 + 2 H2O → 6 F− + SiO2 + 4 H+

Alkali and alkaline earth salts
Neutralization of solutions of Hexafluorosilicic Acid with alkali metal bases produces the corresponding alkali metal fluorosilicate salts:
H2SiF6 + 2 NaOH → Na2SiF6 + 2 H2O

The resulting salt Na2SiF6 is mainly used in water fluoridation.
Related ammonium and barium salts are produced similarly for other applications.
At room temperature 15-30% concentrated hexafluorosilicic acid undergoes similar reactions with chlorides, hydroxides, and carbonates of alkali and alkaline earth metals.

Sodium hexafluorosilicate for instance may be produced by treating sodium chloride (NaCl) by hexafluorosilicic acid:
2NaCl + H2SiF6 27 °C→ Na2SiF6↓ + 2 HClBaCl2 + H2SiF6 27 °C→ BaSiF6↓ + 2 HCl
Heating sodium hexafluorosilicate gives silicon tetrafluoride:[9]: 8 
Na2SiF6 >400 °C→ SiF4 + 2 NaF



AIR AND WATER REACTIONS OF HEXAFLUOROSILICIC ACID:
Hexafluorosilicic Acid fumes in air.
Hexafluorosilicic Acid is soluble in water with release of heat and corrosive fumes.



REACTIVITY PROFILE OF HEXAFLUOROSILICIC ACID:
Hexafluorosilicic Acid can react with strong acids (such as sulfuric acid) to release fumes of toxic hydrogen fluoride.
Hexafluorosilicic Acid attacks glass and materials containing silica.
Hexafluorosilicic Acid reacts exothermically with chemical bases (examples: amines, amides, inorganic hydroxides).

Hexafluorosilicic Acid reacts with active metals, including iron and aluminum to dissolve the metal and liberate hydrogen and/or toxic gases.
Hexafluorosilicic Acid can initiate polymerization in certain alkenes.
Hexafluorosilicic Acid reacts with cyanide salts and compounds to release gaseous hydrogen cyanide.

Additional gas-generating reactions may occur with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), and carbonates.
Hexafluorosilicic Acid can catalyze (increase the rate of) chemical reactions.
Hexafluorosilicic Acid decomposes when heated to the boiling point to produce very toxic and corrosive hydrogen fluoride gas.



STRUCTURE OF HEXAFLUOROSILICIC ACID:
The hydrogen bonding between the fluoride and protons are indicated by dashed lines.
Color code: green = F, orange = Si, red = O, gray = H.
Structure of (H5O2)2SiF6.

The hydrogen bonding between the fluoride and protons are indicated by dashed lines.
Color code: green = F, orange = Si, red = O, gray = H.
Hexafluorosilicic Acid has been crystallized as various hydrates.

These include (H5O2)2SiF6, the more complicated (H5O2)2SiF6·2H2O, and (H5O2)(H7O3)SiF6·4.5H2O.
In all of these salts, the octahedral hexafluorosilicate anion is hydrogen bonded to the cations.
Aqueous solutions of Hexafluorosilicic Acid are often described as H2SiF6.



PRODUCTION AND PRINCIPAL REACTIONS OF HEXAFLUOROSILICIC ACID:
Hexafluorosilicic Acid is produced commercially from fluoride-containing minerals that also contain silicates.
Specifically, apatite and fluorapatite are treated with sulfuric acid to give phosphoric acid, a precursor to several water-soluble fertilizers.
This is called the wet phosphoric acid process.

As a by-product, approximately 50 kg of Hexafluorosilicic Acid is produced per tonne of HF owing to reactions involving silica-containing mineral impurities.
Some of the hydrogen fluoride (HF) produced during this process in turn reacts with silicon dioxide (SiO2) impurities, which are unavoidable constituents of the mineral feedstock, to give silicon tetrafluoride.

Thus formed, the silicon tetrafluoride reacts further with HF.
The net process can be described as:
6 HF + SiO2 → SiF2−6 + 2 H3O+
Hexafluorosilicic Acid can also be produced by treating silicon tetrafluoride with hydrofluoric acid.



PHYSICAL and CHEMICAL PROPERTIES of HEXAFLUOROSILICIC ACID:
Molecular Weight: 144.091 g/mol
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 0
Exact Mass: 143.98299557 g/mol
Monoisotopic Mass: 143.98299557 g/mol
Topological Polar Surface Area: 0Ų
Heavy Atom Count:7
Formal Charge: 0
Complexity: 62.7
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Molecular Weight: 144.09

Exact Mass: 143.98300
EC Number 241-034-8
HScode: 28111990
PSA: 0
XLogP3: 2.36540
Appearance: Clear colorless Liquid
Density: 1.22 g/mL at 25 °C
Melting Point: No melting point
Boiling Point: 120 °C (approx)
Flash Point: 108-109°C
Refractive Index: 1.35
Water Solubility: H2O: 1 mg/mL, clear, colorless
Storage Conditions: −20°C
Flammability characteristics: Decomposition by heat produces toxic hydrogen fluoride gas
Boiling point: 108-109°C
Density 1.22 g/mL at 20 °C (lit.) 1.31 g/mL at 25 °C
vapor pressure: 23hPa at 19.85℃
refractive index: 1.3500
Flash point: 108-109°C
storage temp.: −20°C
solubility: H2O: 1 mg/mL, clear, colorless
form: Liquid
pka: 1.83[at 20 ℃]

color: Clear colorless
Specific Gravity: 1.38 (40%)
Water Solubility: Miscible with water.
Hydrolytic Sensitivity 0: forms stable aqueous solutions
Merck: 14,4182
Exposure limits ACGIH: TWA 2.5 mg/m3
NIOSH: IDLH 250 mg/m3; TWA 2.5 mg/m3
Stability: Stable in aqueous solution.
InChIKey: AUJBMDCSBIPDEH-UHFFFAOYSA-N
CAS DataBase Reference: 16961-83-4(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances: FLUOSILICIC ACID
EWG's Food Scores: 1
FDA UNII: 53V4OQG6U1
EPA Substance Registry System: Fluosilicic acid (16961-83-4)
Physical state: clear, liquid
Color: light yellow
Odor: pungent
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: Not applicable

Decomposition temperature: No data available
pH: 1,0 - 1,2 at 10 g/l
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: completely solubleat 20 °C soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,31 g/cm3
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: No data available
Boiling Point: 108°C to 109°C
Linear Formula: H2SiF6
UN Number: UN1778
Merck Index: 14,4182
Solubility Information: Miscible with water.
Formula Weight: 144.09
Density: 1.32
Chemical Name or Material: Hexafluorosilicic acid

Compound Formula: H2SiF6
Molecular Weight: 144.09
Appearance: Light yellow liquid
Melting Point: N/A
Boiling Point: N/A
Density: 1.22 g/mL @ 20°C
Solubility in H2O: N/A
Exact Mass: 143.982996
Monoisotopic Mass: 143.982996
Linear Formula: H2SiF6
MDL Number: MFCD00036289
EC No.: 241-034-8
Pubchem CID: 1.11373E+15
IUPAC Name: tetrafluorosilane; dihydrofluoride
SMILES: F.F.F[Si](F)(F)F
InchI Identifier: InChI=1S/F4Si.2FH/c1-5(2,3)4;;/h;2*1H
InchI Key: ZEFWRWWINDLIIV-UHFFFAOYSA-N
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 1.22000 @ 25.00 °C.

CAS: 16961-83-4
EINECS: 241-034-8
InChI: InChI=1/FHO2Si/c1-4(2)3/h2H
InChIKey: AUJBMDCSBIPDEH-UHFFFAOYSA-N
Molecular Formula: F6H2Si
Molar Mass: 144.09
Density: 1.22 g/mL at 20 °C (lit.)1.31 g/mL at 25 °C
Boling Point: 108-109°C
Flash Point: 108-109°C
Water Solubility: Miscible with water.
Solubility: H2O: 1mg/mL, clear, colorless
Vapor Presure: 23hPa at 19.85℃
Appearance: Liquid
Specific Gravity: 1.38 (40%)
Color: Clear colorless
Merck: 14,4182
pKa: 1.83[at 20 ℃]
Storage Condition: −20°C
Stability: Stable in aqueous solution.
Sensitive: 0: forms stable aqueous solutions
Refractive Index: 1.3500



FIRST AID MEASURES of HEXAFLUOROSILICIC ACID:
Description of first-aid measures:
*General advice:
Prevention of absorption of the fluoride ion in cases of ingestion can be obtained by giving milk, chewable calcium carbonate tablets or Milk of Magnesia to conscious victims.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
First treatment with calcium gluconate paste.
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Call a physician immediately.
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXAFLUOROSILICIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up with liquid-absorbent and neutralising material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXAFLUOROSILICIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXAFLUOROSILICIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Acid-resistant protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXAFLUOROSILICIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Do not store in glass
*Storage class:
Storage class (TRGS 510): 6.1D: Non-combustible



STABILITY and REACTIVITY of HEXAFLUOROSILICIC ACID:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
Hexafluorosilicic acid
Fluorosilicic acid
16961-83-4
Dihydrogen hexafluorosilicate
Silicate(2-), hexafluoro-, dihydrogen
Silicon hexafluoride dihydride
Fluorosilicic acid (H2SiF6)
hexafluorosilicon(2-)
hydron
MFCD00036289
FLUOROSILIC ACID
Kieselfluorwasserstoffsaure
FLUOSILICIC ACID [MI]
53V4OQG6U1
DTXSID2029741
Dihydrogen hexafluorosilicate(2-)
OHORFAFFMDIQRR-UHFFFAOYSA-P
NSC-16894
hexakis(fluoranyl)silicon(2-)
hydron
FT-0626488
HYDROGEN HEXAFLUOROSILICATE (H2SIF6)
HEXAFLUOROSILICATE(2-)HYDROGEN (1:2)
FLUOSILICIC ACID (HYDROFLUOSILICIC ACID)
A811126
Q411250
J-521443
ACTH
FLUOROSILICIC ACID
FLUOSILICIC ACID
SILICOFLUORIC ACID
HEXAFLUOSILICIC ACID
Hexafluorosilic acid
HYDROFLUOSILICIC ACID
HYDROFLUOROSILICIC ACID
ACTH 1-39
Sand acid
Silicate(2-),hexafluoro-,hydrogen (1:2)
Silicate(2-),hexafluoro-,dihydrogen
Fluosilicic acid
Dihydrogen hexafluorosilicate
Hexafluorosilicic acid
Hydrofluorosilicic acid
Fluorosilicic acid
Fluorosilicic acid (H2SiF6)
Silicon hexafluoride dihydride
Dihydrogen hexafluorosilicate(2-)
Hydrogen hexafluorosilicate (H2SiF6)
NSC 16894
Hydrosilicofluoric acid
1309-45-1
12672-67-2
1202864-64-9
Fluorosilicic acid
Hexafluorosilicic acid
Hydrogen hexafluorosilicate
Fluosilicic acid
Dihydrogen hexafluorosilicate
Dihydrogen hexafluorosilicate (2-)
FKS
Hexafluorosilicic acid
Hexafluosilicic acid
Hydrofluorosilicic acid
Hydrofluosilicic acid
Hydrogen hexafluorosilicate
Hydrosilicofluoric acid
Sand acid
Silicate (2-), hexafluoro-, dihydrogen
Silicofluoric acid
Silicofluoride
Silicon hexafluoride dihydride
Silicate(2-), hexafluoro-, hydrogen (1:2)
16961-83-4
hexafluorosilicate
Fluorosilicic acid
SILICOFLUORIC ACID
HYDROFLUOSILICIC ACID
Hydrofluosilicic acid
Hexafluorosilicic Acid
HYDROSILICOFLUORIC ACID
HYDROFLUOROSILICIC ACID
silicate(2-), hexafluoro-
HYDROGEN HEXAFLUOROSILICATE
tetrafluorosilane dihydrofluoride



HEXAFLUOROZIRCONIC ACID

Hexafluorozirconic acid is a chemical compound with the molecular formula H2ZrF6.
Hexafluorozirconic acid is an inorganic acid that is composed of zirconium (Zr) and fluorine (F) atoms.
Hexafluorozirconic acid is highly soluble in water and forms a colorless to pale yellow solution.

CAS Number: 12021-95-3
EC Number: 234-619-9



APPLICATIONS


Hexafluorozirconic acid is commonly used in metal surface treatment processes, such as etching, cleaning, and passivation.
Hexafluorozirconic acid finds application in the aerospace industry for surface preparation of metal components prior to coating or painting.
Hexafluorozirconic acid is used in the automotive industry for the removal of rust, scale, and oxide layers from metal surfaces.

Hexafluorozirconic acid is employed in the electronics industry for the cleaning and etching of printed circuit boards (PCBs) during the manufacturing process.
Hexafluorozirconic acid is used in the production of ceramic coatings, providing enhanced durability and corrosion resistance.
Hexafluorozirconic acid finds application in the manufacturing of refractory materials, ceramics, and glass.

Hexafluorozirconic acid is utilized as an additive in electrolytes for energy storage devices, such as batteries and fuel cells, to enhance their performance.
Hexafluorozirconic acid is employed in the production of zirconium-based catalysts for various organic reactions.
Hexafluorozirconic acid is used as a flux in soldering and brazing processes to facilitate the flow and adhesion of solder or brazing material.

Hexafluorozirconic acid is utilized in the production of specialty glasses with high refractive indices and optical properties.
Hexafluorozirconic acid finds application in the manufacturing of pigments and dyes, providing coloration and UV resistance.

Hexafluorozirconic acid is used in water treatment processes to adjust pH levels and aid in the removal of certain impurities.
Hexafluorozirconic acid is employed in the synthesis of zirconium compounds, such as zirconium dioxide (ZrO2).
Hexafluorozirconic acid is used as a raw material in the production of zirconium salts for various applications.
Hexafluorozirconic acid finds application in the production of high-quality ceramic tiles with enhanced strength and resistance properties.

Hexafluorozirconic acid is utilized in the fabrication of optical fibers for telecommunications and fiber-optic applications.
Hexafluorozirconic acid is used in the formulation of specialty coatings and paints for corrosion protection.
Hexafluorozirconic acid finds application in the manufacturing of dental ceramics and dental prosthetics.

Hexafluorozirconic acid is used in the production of abrasives and grinding materials for various industries.
Hexafluorozirconic acid is employed in the formulation of specialty adhesives and sealants.
Hexafluorozirconic acid is used as an intermediate in the synthesis of other zirconium compounds and complex materials.
Hexafluorozirconic acid finds application in the production of specialty ceramics, such as ceramic membranes and filters.

Hexafluorozirconic acid is utilized in the surface treatment of metal alloys to enhance their corrosion resistance.
Hexafluorozirconic acid is used in the formulation of specialty detergents and cleaning agents.
Hexafluorozirconic acid finds application in the preservation and restoration of historical metal artifacts and artworks.
Hexafluorozirconic acid is used in the manufacturing of electroplating solutions for metal finishing processes.

Hexafluorozirconic acid finds application in the production of corrosion-resistant coatings for metal surfaces, such as pipes and tanks.
Hexafluorozirconic acid is utilized in the formulation of specialty glass-cleaning solutions for optical lenses and glassware.
Hexafluorozirconic acid is employed in the treatment of aluminum surfaces to improve adhesion for subsequent processes.

Hexafluorozirconic acid finds application in the production of flame-retardant materials, such as fire-resistant coatings and textiles.
Hexafluorozirconic acid is used in the formulation of specialty paints and coatings for high-performance industrial applications.
Hexafluorozirconic acid is employed in the preparation of metal catalysts for chemical reactions and industrial processes.
Hexafluorozirconic acid finds application in the manufacturing of high-quality ceramic capacitors for electronic devices.

Hexafluorozirconic acid is used in the production of specialty ceramics for advanced structural and functional applications.
Hexafluorozirconic acid finds application in the formulation of specialty adhesives for high-strength bonding applications.
Hexafluorozirconic acid is utilized in the manufacturing of corrosion inhibitors for various metal surfaces and systems.

Hexafluorozirconic acid is employed in the production of dental materials, such as dental cements and dental restorations.
Hexafluorozirconic acid is used in the formulation of specialty metalworking fluids and cutting oils.
It finds application in the treatment of metal alloys for improved surface hardness and wear resistance.

The acid is employed in the production of heat-resistant materials, such as refractory bricks and liners.
Hexafluorozirconic acid finds application in the formulation of specialty coatings for solar panels and photovoltaic devices.
Hexafluorozirconic acid is used in the manufacturing of catalysts for selective hydrogenation reactions in the chemical industry.

Hexafluorozirconic acid is utilized in the formulation of specialty detergents for industrial cleaning applications.
Hexafluorozirconic acid finds application in the production of high-quality pigments for ink and paint industries.
Hexafluorozirconic acid is employed in the treatment of metal surfaces prior to adhesive bonding in aerospace applications.

Hexafluorozirconic acid is used in the production of specialty ceramics used in the semiconductor industry.
Hexafluorozirconic acid finds application in the formulation of specialty lubricants and anti-friction coatings.
Hexafluorozirconic acid is utilized in the synthesis of zirconium-based nanoparticles for various advanced materials.
Hexafluorozirconic acid is used in the production of specialty resins and polymers with enhanced heat and chemical resistance.
Hexafluorozirconic acid finds application in the formulation of specialty concrete additives for improved strength and durability.


Hexafluorozirconic acid (H2ZrF6) has several applications across various industries due to its unique properties.
Here are some common applications of hexafluorozirconic acid:

Metal surface treatment:
Hexafluorozirconic acid is widely used for etching, cleaning, and passivating metal surfaces, especially in the aerospace, automotive, and electronics industries.
Hexafluorozirconic acid helps to remove impurities and provide a clean and activated surface for subsequent processes like plating or coating.

Ceramic production:
The acid is utilized in the manufacturing of ceramic products, including ceramic coatings, tiles, and refractory materials.
Hexafluorozirconic acid helps improve the mechanical properties and corrosion resistance of ceramics, enhancing their performance and durability.

Electronics manufacturing:
Hexafluorozirconic acid is employed in the electronics industry for various purposes.
Hexafluorozirconic acid is used in the etching of printed circuit boards (PCBs) to remove unwanted copper traces and create circuit patterns.
Hexafluorozirconic acid also finds use in cleaning semiconductor surfaces during the fabrication of electronic components.

Catalyst synthesis:
Hexafluorozirconic acid serves as a precursor in the synthesis of zirconium-based catalysts.
These catalysts find applications in a wide range of organic reactions, including polymerization, hydrogenation, and oxidation processes.

Specialty glasses:
Hexafluorozirconic acid is used in the production of specialty glasses, such as high-refractive-index glasses and glass coatings.
Hexafluorozirconic acid contributes to the optical properties and stability of these glasses, making them suitable for applications in optics, lasers, and telecommunications.

Electrolyte additives:
Hexafluorozirconic acid is utilized as an additive in electrolytes for energy storage devices, including batteries and fuel cells.
Hexafluorozirconic acid helps improve the ionic conductivity and stability of the electrolyte, enhancing the performance and efficiency of these energy storage systems.

Flux in soldering and brazing:
Hexafluorozirconic acid is employed as a flux in soldering and brazing processes.
Hexafluorozirconic acid helps to remove metal oxide layers and promote wetting between the solder or brazing material and the metal surface, ensuring strong and reliable bonds.

Pigments and dyes:
Hexafluorozirconic acid is used in the production of certain pigments and dyes, particularly those based on zirconium compounds.
These pigments find application in paints, coatings, plastics, and textiles, providing coloration and UV resistance.

Water treatment:
Hexafluorozirconic acid is sometimes used in water treatment processes to control pH levels and remove impurities.
Hexafluorozirconic acid can be employed to adjust the alkalinity or acidity of water and aid in the precipitation or removal of specific ions.

Laboratory reagent:
Hexafluorozirconic acid serves as a useful laboratory reagent for various chemical reactions and research purposes.
Hexafluorozirconic acid can be utilized as a source of zirconium ions or as a strong acid in certain experimental setups.



DESCRIPTION


Hexafluorozirconic acid is a chemical compound with the molecular formula H2ZrF6.
Hexafluorozirconic acid is an inorganic acid that is composed of zirconium (Zr) and fluorine (F) atoms.
Hexafluorozirconic acid is highly soluble in water and forms a colorless to pale yellow solution.

Hexafluorozirconic acid is commonly used in various industrial applications, particularly in the field of metal surface treatment, ceramic production, and electronics manufacturing.
Hexafluorozirconic acid possesses strong acidic properties and reacts with a wide range of metals, metal oxides, and metal salts.

Hexafluorozirconic acid is an inorganic compound with a molecular formula of H2ZrF6.
Hexafluorozirconic acid is a colorless to pale yellow liquid with a strong acidic odor.
Hexafluorozirconic acid is highly soluble in water, forming a clear and acidic solution.

Hexafluorozirconic acid is corrosive and can cause severe burns to the skin and eyes.
Hexafluorozirconic acid is primarily used in metal surface treatment processes, such as etching, cleaning, and passivation.
Hexafluorozirconic acid reacts with various metals, metal oxides, and metal salts, forming stable complexes.

Hexafluorozirconic acid is employed in the production of ceramic coatings, providing enhanced durability and corrosion resistance.
Hexafluorozirconic acid serves as a raw material in the synthesis of zirconium compounds, such as zirconium dioxide (ZrO2).
Hexafluorozirconic acid finds application in the electronics industry for etching and cleaning semiconductor surfaces.

Hexafluorozirconic acid is utilized in the preparation of zirconium-based catalysts for organic reactions.
Hexafluorozirconic acid is a source of zirconium fluoride, which is used as a flux in soldering and brazing processes.

Hexafluorozirconic acid can be employed in the production of specialty glasses, ceramics, and pigments.
Hexafluorozirconic acid is used as an additive in electrolytes for energy storage devices, including batteries and fuel cells.
Hexafluorozirconic acid exhibits strong oxidizing properties and can react with reducing agents, releasing toxic fluorine gas.

Hexafluorozirconic acid is highly reactive with alkaline substances, forming water-insoluble zirconium compounds.
Hexafluorozirconic acid is a hazardous substance that should be handled with appropriate safety precautions.
Hexafluorozirconic acid should be stored in tightly sealed containers away from heat, moisture, and incompatible substances.

Hexafluorozirconic acid is classified as a dangerous goods item and must be transported in accordance with regulations.
Hexafluorozirconic acid has a molecular weight of approximately 207.21 grams per mole.
Its boiling point is around 150-160 degrees Celsius.
Hexafluorozirconic acid can release irritating or toxic fumes when heated or exposed to fire.
Hexafluorozirconic acid is soluble in polar solvents such as acetone, methanol, and ethanol.

Hexafluorozirconic acid has a strong affinity for hydroxide ions, making it a potent acid in aqueous solutions.
Hexafluorozirconic acid is stable under normal conditions but can decompose at elevated temperatures.
Hexafluorozirconic acid is a versatile compound with a wide range of applications, particularly in the fields of metal surface treatment, ceramics, and electronics.



PROPERTIES


Chemical Formula: H2ZrF6
Molecular Weight: 207.22 g/mol
Appearance: Colorless or pale yellow liquid
Odor: Sharp, pungent odor
Density: 2.49 g/cm³
Melting Point: -15.3°C (-4.5°F)
Boiling Point: 150°C (302°F)
Solubility: Soluble in water and organic solvents like ethanol and acetone
pH: Highly acidic, typically below 1
Vapor Pressure: Low to moderate vapor pressure
Viscosity: Relatively low viscosity
Flammability: Not flammable
Reactivity: Highly reactive with strong oxidizing agents and bases
Stability: Stable under normal conditions, but may decompose upon heating or exposure to certain conditions
Corrosivity: Highly corrosive to metals and may cause damage to reactive surfaces
Hygroscopicity: Absorbs moisture from the air, forming hydrates
Toxicity: Can cause severe irritation and burns to the skin, eyes, and respiratory system
Hazardous Combustion Products: Hydrogen fluoride (HF) gas and toxic fumes
Environmental Impact: Harmful to aquatic life and the environment, should be handled with care
Reactivity with Water: Reacts exothermically with water, releasing hydrogen fluoride gas
Oxidizing Properties: Can act as an oxidizing agent in certain reactions
Dissociation: Partially dissociates in water, releasing hydrogen ions (H+) and hexafluorozirconate ions (ZrF6^2-)



FIRST AID


General Advice:

Ensure personal protective equipment (PPE) is worn by individuals providing first aid.
Keep contaminated individuals warm and at rest.
Prevent further exposure and avoid contact with eyes, skin, and clothing.
Promptly remove contaminated clothing and wash thoroughly before reuse.
If necessary, transfer the individual to a medical facility for further evaluation and treatment.

Inhalation:

Move the affected person to fresh air and ensure they are in a well-ventilated area.
If breathing is difficult, provide oxygen if available and seek immediate medical attention.
If the person is not breathing, perform artificial respiration and seek medical help.

Skin Contact:

Immediately remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes.
Use mild soap if available.
Avoid using hot water, as it may increase absorption through the skin.
Seek medical attention if irritation, redness, or pain persists after thorough rinsing.

Eye Contact:

Rinse the eyes gently but thoroughly with water for at least 15 minutes, keeping the eyelids open to ensure thorough flushing.
Remove contact lenses, if applicable, after initial rinsing.
Seek immediate medical attention, even if there are no initial symptoms of irritation or pain.

Ingestion:

Rinse the mouth thoroughly with water, but do not induce vomiting unless instructed to do so by medical personnel.
If the person is conscious and alert, provide small sips of water to rinse the mouth and drink water in small amounts to dilute the acid.
Do not give anything by mouth to an unconscious or convulsing person.
Seek immediate medical attention.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles or face shield, and protective clothing to prevent skin and eye contact.

Ventilation:
Handle in a well-ventilated area or use local exhaust ventilation to maintain air quality and prevent the buildup of fumes.

Avoid Inhalation:
Avoid breathing in vapors or mists.
If working in an enclosed space, use respiratory protection such as a properly fitted NIOSH-approved respirator.

Contamination Prevention:
Prevent contamination of other materials by using dedicated equipment and containers for handling the acid.
Avoid contact with incompatible substances.

Spill and Leak Response:
In the event of a spill or leak, contain the area and prevent further release into the environment.
Absorb small spills with an inert absorbent material and dispose of it according to regulations.


Storage:

Storage Area:
Store hexafluorozirconic acid in a cool, dry, well-ventilated area away from incompatible materials, sources of ignition, and direct sunlight.

Temperature Control:
Maintain storage temperature below 30°C (86°F) to prevent decomposition or hazardous reactions.

Containers:
Use appropriate containers made of compatible materials, such as high-density polyethylene (HDPE) or glass, that are tightly sealed to prevent leaks or spills.

Labeling:
Clearly label containers with the product name, concentration, hazard symbols, and any necessary warning information.

Accessibility:
Store containers in a designated area, clearly marked and accessible only to authorized personnel who are trained in handling hazardous chemicals.

Separation:
Separate hexafluorozirconic acid from incompatible substances, including strong oxidizing agents, bases, and reactive metals.

Secondary Containment:
Consider using secondary containment measures, such as spill containment pallets, to prevent leaks or spills from reaching the surrounding environment.



SYNONYMS


Zirconium hexafluoride
Zirconium fluoride
Zirconium(IV) fluoride
Zirconium(IV) hexafluoride
Zirconium(IV) fluoride hexahydrate
Zirconium fluoride hydrate
Zirconium(IV) fluoride solution
Zirconium hexafluoride solution
Zirconium(IV) fluoride complex
Zirconium(IV) fluoride hydrate complex
Zirconium(IV) fluoride hexahydrate complex
Zirconium fluoride complex solution
Zirconium fluoride hydrate complex solution
Hexafluorozirconic acid solution
Hexafluorozirconic acid hydrate
Hexafluorozirconic acid hydrate solution
Hexafluorozirconic acid hexahydrate
Hexafluorozirconic acid hexahydrate solution
Zirconium(IV) fluoride hexahydrate solution
Zirconium hexafluoride hydrate
Zirconium hexafluoride hydrate solution
Zirconium(IV) fluoride hydrate solution
Zirconium(IV) fluoride hexahydrate hydrate solution
Zirconium(IV) fluoride hexahydrate hydrate complex
Zirconium fluoride hexahydrate hydrate complex solution
Zirconium(IV) hexafluorozirconate
Zirconium(IV) hexafluoride complex
Zirconium(IV) fluoride hydrate complex
Zirconium(IV) fluoride hexahydrate hydrate complex solution
Zirconium(IV) fluoride hexahydrate hydrate complex solution
Zirconium fluoride hexahydrate hydrate complex
Zirconium(IV) fluoride hexahydrate hydrate
Zirconium(IV) fluoride hexahydrate hydrate solution
Hexafluorozirconate acid
Hexafluorozirconate hydrate
Hexafluorozirconate solution
ZrF6
Zirconium(IV) fluoride solution
Zirconium(IV) fluoride complex solution
Zirconium(IV) fluoride hydrate solution
Zirconium(IV) fluoride hexahydrate solution
Zirconium hexafluoride hydrate complex
Zirconium hexafluoride hydrate complex solution
Zirconium hexafluoride hydrate solution
Zirconium hexafluorozirconate hydrate
Zirconium hexafluorozirconate hydrate solution
Zirconium hexafluorozirconate solution
Zirconium fluoride complex solution
Zirconium fluoride hydrate complex solution
Zirconium fluoride hydrate solution
Zirconium(IV) hexafluoride acid
Zirconium(IV) fluoride hexahydrate acid
Zirconium(IV) fluoride hydrate acid solution
Hexafluorozirconic acid hydrate complex
Hexafluorozirconic acid hexahydrate hydrate complex
Hexafluorozirconic acid hexahydrate hydrate complex solution
Zirconium(IV) fluoride hexahydrate hydrate complex acid
Zirconium(IV) fluoride hexahydrate hydrate complex acid solution
Zirconium(IV) fluoride hexahydrate hydrate acid
Zirconium(IV) fluoride hexahydrate hydrate acid solution
Zirconium(IV) fluoride hexahydrate hydrate acid complex
Zirconium(IV) fluoride hexahydrate hydrate acid complex solution
Zirconium(IV) fluoride hexahydrate hydrate acid solution
Zirconium(IV) fluoride hexahydrate hydrate acid complex
Hexafluorozirconic acid hexahydrate hydrate acid
Hexafluorozirconic acid hexahydrate hydrate acid solution
Hexafluorozirconic acid hexahydrate hydrate acid complex
Zirconium hexafluoride hydrate acid complex
Zirconium hexafluoride hydrate acid complex solution
Zirconium hexafluoride hydrate acid solution
Zirconium hexafluoride hydrate acid
Zirconium hexafluoride hydrate acid solution
Zirconium hexafluoride hydrate acid complex
Zirconium hexafluorozirconate hydrate acid
Zirconium hexafluorozirconate hydrate acid solution
HEXAFLUOROZIRCONIC ACID
HHPA;NT 907; C6H10(CO)2O; Araldite HT 907; Lekutherm Hardener H; Hexahydrophthalic an; CALCIUM 2-NAPTHYLPHOSPHATE; Hexahydro benzoicanhydride; HEXAHYDROPHTHALIC ANHYDRIDE; Hexahydrophthalsureanhydrid CAS NO:85-42-7
HEXAFLUOROZIRCONIC ACID (HFZA)
Hexafluorozirconic acid (HFZA) is white or of-white powder or crystalline powder, and odorless.
Hexafluorozirconic acid (HFZA) is a solution of dihydrogen hexafluorozirconate containing a small percentage of hydrogen fluoride and used in the phosphating process for metal plating.


CAS Number: 12021-95-3
EC Number: 234-666-0
MDL Number: MFCD00082965
Molecular Formula: F4Zr.2FH
Linear Formula: H2ZrF6


Hexafluorozirconic acid (HFZA) is an inorganic compound that exists in two forms: a solid and a liquid.
Hexafluorozirconic acid (HFZA) is a solution of dihydrogen hexafluorozirconate containing a small percentage of hydrogen fluoride and used in the phosphating process for metal plating.


Hexafluorozirconic acid (HFZA) is an alternative to nickel in this process because nickel is subject to environmental regulation.
Hexafluorozirconic acid (HFZA) reduces considerably the formation of sludge byproducts compared to zinc-phosphate-based systems and it also can be plugged into production lines easily, with little or no modifications.


Hexafluorozirconic acid (HFZA) is the preferred choice when replacing zinc-phosphate ahead of an electrocoat painting system.
Hexafluorozirconic acid (HFZA) is a non-flammable.
Hexafluorozirconic acid (HFZA) is white or of-white powder or crystalline powder, and odorless.


Hexafluorozirconic acid (HFZA) is incompatible with strong acids, bases, and should be stored away from metals as contact with metals can result in the release of hydrogen gas that can be explosive.
This mixture is predominantly composed of 45% dihydrogen hexafluorozirconate(2-), 54.5% water and hydrofluoric acid comprising approximately 0.5%.


Hexafluorozirconic acid (HFZA) is very soluble in N,N-Dimethylformamide, Soluble in methanol, Sparingly soluble in glacial acetic acid, Very slightly soluble in chloroform, and Practically insoluble in water.
Hexafluorozirconic acid (HFZA) is known to have chemical formula F6H2Zr with molecular weight of 207.23 g/mol.


Hexafluorozirconic acid (HFZA) is also utilized in medical & pharmaceutical industries for various formulations.
Hexafluorozirconic acid (HFZA) is completely free from impurities and can be availed at highly competitive rates in bulk amounts.
Hexafluorozirconic acid (HFZA) is a light green liquid


Hexafluorozirconic acid (HFZA) is a colorless, odorless liquid mixture, completely soluble in water and stable under recommended storage conditions.
Hexafluorozirconic acid (HFZA) is corrosive to metals.


Hexafluorozirconic acid (HFZA) is a colorless and transparent liquid, which is acidic and has a specific gravity of about 1.48.
At room temperature, when the concentration exceeds 42%, Hexafluorozirconic acid (HFZA) is precipitated.
Hexafluorozirconic acid (HFZA) is an organic compound with the formula H2ZrF6.


With the CAS registry number 12021-95-3, Hexafluorozirconic acid (HFZA) is also named as fluorozirconic acid.
Hexafluorozirconic acid (HFZA)'s category is Inorganics.
Besides, Hexafluorozirconic acid (HFZA) should be stored in a a cool closed and well-ventilated place.


Hexafluorozirconic acid (HFZA) is a colorless and transparent liquid, which is acidic and has a specific gravity of about 1.48.
At room temperature, when the concentration exceeds 42%, Hexafluorozirconic acid (HFZA) is precipitated.
Hexafluorozirconic acid (HFZA) is a colorless liquid with a characteristic smell odor of hydrogen fluoride.



USES and APPLICATIONS of HEXAFLUOROZIRCONIC ACID (HFZA):
Hexafluorozirconic acid (HFZA) is used in based surface pretreatments on steel for corrosion resistance.
Hexafluorozirconic acid (HFZA) is used Preparation of titania photocatalyst synthesized from the ionic-liquid-like precursor.
Hexafluorozirconic acid (HFZA) is used synthesis of fluoride-releasing dental monomers.


Hexafluorozirconic acid (HFZA) is also used in optical glass, salt manufacturing, in chromate solution can improve the corrosion resistance of steel, zinc, lead and other metals.
Hexafluorozirconic acid (HFZA) is used in the manufacture of optical glass and fluorozirconate.


Hexafluorozirconic acid (HFZA) is used for metal surface treatment and cleaning.
Hexafluorozirconic acid (HFZA) is used in the pre-treatment of aluminum prior to surface finishing, for example, prior to painting aluminum beverage cans, automotive surfaces and appliances.


Hexafluorozirconic acid (HFZA) is used for Electroplating.
Hexafluorozirconic acid (HFZA) is used in wool, leather industry, atomic energy industry and the production of advanced electrical materials, refractories.
Hexafluorozirconic acid (HFZA) is used in the following products, often in combination with our Fluorotitanic Acid:


Hexafluorozirconic acid (HFZA) is used Aluminium pre-treatment solutions chrome-free processes.
Hexafluorozirconic acid (HFZA) is used Metal surface treatment, Automotive, and Paint.
Hexafluorozirconic acid (HFZA) is a highly reactive compound that is used in a variety of scientific and industrial applications.


Hexafluorozirconic acid (HFZA) is primarily used as a catalyst in the synthesis of organic compounds, as a reagent in the synthesis of fluorinated compounds, and as a reagent for the production of fluorinated polymers.
Hexafluorozirconic acid (HFZA) is also used in the manufacture of semiconductor materials and in the production of high-strength glass.


Hexafluorozirconic acid (HFZA) is mainly used in manufacturing of optical glass and fluozirconate.
Hexafluorozirconic acid (HFZA) is used in based surface pretreatments on steel for corrosion resistance
Hexafluorozirconic acid (HFZA) is used Preparation of titania photocatalyst synthesized from ionic-liquid-like precursor


Hexafluorozirconic acid (HFZA) is used for metal surface treatment and cleaning, also used in the atomic energy industry and advanced electrical materials, refractory production
Hexafluorozirconic acid (HFZA) is used as precursor to ZrO2 ceramic thin films.


Hexafluorozirconic acid (HFZA) is used commonly in industrial settings as a precursor material for the manufacture of films used to coat ceramics, to synthesize glass used in prescription eyeglasses and as a common corrosion inhibitor on steel and other metal surfaces.
Hexafluorozirconic acid (HFZA) is used Synthesis of fluoride-releasing dental monomer


Hexafluorozirconic acid (HFZA) is used as precursor to ZrO2 ceramic thin films
Hexafluorozirconic acid (HFZA) is used in the pre-treatment of aluminum prior to surface finishing, for example, prior to painting aluminum beverage cans, automotive surfaces and appliances.


Hexafluorozirconic acid (HFZA) is also used in optical glass, zirconium fluoride acid salt manufacturing, in chromate solution can improve the corrosion resistance of steel, zinc, lead and other metals.
Hexafluorozirconic acid (HFZA) is used as a precursor to ZrO2 ceramic thin films.


Hexafluorozirconic acid (HFZA) is used as raw materials for zirconium, magnesium alloy, catalyst, steel and non-ferrous metal alloy, as well as atomic energy industry and advanced electrical materials, refractories, electric vacuum technology materials, optical glass materials, pyrotechnics, ceramics, enamel and glass production.


Hexafluorozirconic acid (HFZA) finds most common application for preparation of photocatalysts, titanium dioxide, & thin films of zirconium oxide.
Hexafluorozirconic acid (HFZA) can be used for metal surface preparation and cleaning.
Hexafluorozirconic acid (HFZA) is also used for treatment of metal's surface so as to improve its properties.


Hexafluorozirconic acid (HFZA) is also used in wool, leather garment industry, atomic energy industry and production of advanced electrical materials and refractory materials.
Hexafluorozirconic acid (HFZA) can be used for surface pretreatments on steel for corrosion resistance.


Uses of Hexafluorozirconic acid (HFZA): Surface treatment; Electroplating; Aluminium lacquering in chrome-free processes. Metal Industry; Corrosion inhibitor in surface pre-treatment (aluminium and other metals).
Hexafluorozirconic acid (HFZA) is mainly used as corrosion inhibitor by customers active in the metal and coatings industry.


Hexafluorozirconic acid (HFZA) has multiple uses in inorganic chemical reactions such as the preparation of titanium oxide photocatalysts and zirconium oxide thin films.
Hexafluorozirconic acid (HFZA) is mainly used as corrosion inhibitor by customers active in the metal and coatings industry.


American Elements can produce most materials in high purity and ultra high purity (up to 99.99999%) forms and follows applicable ASTM testing standards; a range of grades are available including Mil Spec (military grade), ACS, Reagent and Technical Grade, Food, Agricultural and Pharmaceutical Grade, Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia).


Further, Hexafluorozirconic acid (HFZA) is used for surface pretreatments on steel to prevent corrosion.
In addition to this, Hexafluorozirconic acid (HFZA) is used in the production of the atomic energy industry, advanced electrical materials and refractories.
Hexafluorozirconic acid (HFZA) does show highest effectiveness on aluminium though it can be used on other metals as well.


Hexafluorozirconic acid (HFZA) is used electroplating, aluminum lacquering in chrome-free processes, synthesis of fluoride-releasing dental monomers, as a precursor of ZrO2 ceramic films as well as metal surface passivation.
Hexafluorozirconic acid (HFZA) reduces the occurrence of sludge as a side product – e.g. in Zincphosphate based systems


Hexafluorozirconic acid (HFZA) is often used in the form of fluozirconate, as raw materials for zirconium chemical compounds, magnesium alloys, catalysts, steel and non-ferrous metal alloys, as well as atomic energy industry and advanced electrical materials, refractory materials, electrical vacuum technology materials, optical glass Raw materials, pyrotechnics, ceramics, etc.


Hexafluorozirconic acid (HFZA) is used Surface treatment; Electroplating; Aluminium lacquering in chrome-free processes.
Metal Industry uses of Hexafluorozirconic acid (HFZA); Corrosion inhibitor in surface pre-treatment (aluminium and other metals).
Hexafluorozirconic acid (HFZA) is used for the production of the atomic energy industry, advanced electrical materials and refractories.


Hexafluorozirconic acid (HFZA) is often used in the form of fluozirconate, as raw materials for zirconium chemical compounds, magnesium alloys, catalysts, steel and non-ferrous metal alloys, as well as atomic energy industry and advanced electrical materials, refractory materials, electrical vacuum technology materials, optical glass Raw materials, pyrotechnics, ceramics, etc.


Hexafluorozirconic acid (HFZA) is mainly used in metal surface treatment and cleaning
Hexafluorozirconic acid (HFZA)'s also used in the wool, leather industry and the atomic energy industry and advanced electrical materials, refractory production etc.


Hexafluorozirconic acid (HFZA) is used for metal surface treatment and cleaning, as well as for atomic energy industry and production of advanced electrical materials and refractories.
Hexafluorozirconic acid (HFZA) is mainly used in manufacturing of optical glass and fluozirconate.


Hexafluorozirconic acid (HFZA) is used for metal surface treatment and cleaning, as well as for wool, leather garment industry, atomic energy industry and production of high-grade electrical materials and refractories.
Hexafluorozirconic acid (HFZA) is used for metal surface and coating.


Hexafluorozirconic acid (HFZA) is used in manufacturing of optical glass and fluozirconate.
Hexafluorozirconic acid (HFZA) acts as a precursor to zirconium dioxide ceramic thin films.


-Hexafluorozirconic acid (HFZA) is used:
*electroplating
*aluminum lacquering in chrome-free processes
*synthesis of fluoride releasing dental monomers, as a precursor of ZrO2 ceramic films as well as metal surface passivation
*Hexafluorozirconic acid reduces the occurrence of sludge as a side product – e.g. in Zincphosphate based systems



FEATURES OF HEXAFLUOROZIRCONIC ACID (HFZA):
*Optimum quality
*Accurate composition
*Long shelf life



FUNCTION OF HEXAFLUOROZIRCONIC ACID (HFZA):
* Hexafluorozirconic acid (HFZA) is used for the manufacture of optical glass and fluorozirconate.
* Hexafluorozirconic acid (HFZA) is used for metal surface treatment and cleaning, also used in wool, leather garment industry, atomic energy industry and production of advanced electrical materials and refractory materials
* Hexafluorozirconic acid (HFZA) is used for metal surfaces and coatings, etc.



SYNTHESIS METHOD OF HEXAFLUOROZIRCONIC ACID (HFZA):
Hexafluorozirconic acid (HFZA) can be synthesized in a number of ways, including the reaction of zirconium dioxide with hydrogen fluoride, the reaction of zirconium oxychloride with hydrofluoric acid, and the reaction of zirconium tetrachloride with hydrofluoric acid.
The reaction of zirconium dioxide with hydrogen fluoride is the most commonly used method of synthesis.
In this method, zirconium dioxide is reacted with hydrogen fluoride in an aqueous solution at a temperature of approximately 70°C.
The reaction produces Hexafluorozirconic acid (HFZA), which is then isolated and purified by distillation.



SYNTHESIS METHOD DETAILS OF HEXAFLUOROZIRCONIC ACID (HFZA):
Design of the Synthesis Pathway
The synthesis of Hexafluorozirconic acid (HFZA) can be achieved through the reaction of Zirconium(IV) oxide with Hydrogen fluoride gas.
Starting Materials:
Zirconium(IV) oxide, Hydrogen fluoride gas



REACTION OF HEXAFLUOROZIRCONIC ACID (HFZA):
Zirconium(IV) oxide is added to a reaction vessel, and Hydrogen fluoride gas is introduced into the reaction vessel.
The reaction mixture is heated to a temperature of 150-200°C.
The reaction proceeds to form Hexafluorozirconic acid (HFZA).
The Hexafluorozirconic acid (HFZA) is then purified through distillation or precipitation methods



SCIENTIFIC RESEARCH APPLICATION OF HEXAFLUOROZIRCONIC ACID (HFZA):
Hexafluorozirconic acid (HFZA) is used in a variety of scientific research applications, including the synthesis of organic compounds, the synthesis of fluorinated compounds, and the production of fluorinated polymers.
Hexafluorozirconic acid (HFZA) is also used in the production of semiconductor materials and in the manufacture of high-strength glass.
In addition, Hexafluorozirconic acid (HFZA) is used as a reagent in the synthesis of organometallic compounds and in the production of high-performance polymers.



MECHANISM OF ACTION OF HEXAFLUOROZIRCONIC ACID (HFZA):
The mechanism of action of Hexafluorozirconic acid (HFZA) is not fully understood.
It is believed that Hexafluorozirconic acid (HFZA) acts as a Lewis acid, which means that it can form a bond with an electron-rich species, such as a Lewis base.
This bond can then be used to catalyze the formation of a new bond between two molecules.
Additionally, Hexafluorozirconic acid (HFZA) can act as a nucleophile, which means that it can react with electron-deficient species, such as electrophiles.



PHYSICAL and CHEMICAL PROPERTIES of HEXAFLUOROZIRCONIC ACID (HFZA):
Molecular Weight: 207.23000
Exact Mass: 205.91100
XLogP3: 2.74620
Appearance: Clear Colourless solution
Density: 1.52
Flash Point: None
CAS No.: 12021-95-3
Molecular Formula: F4Zr.2FH
Molecular weight: 207.23
Appearance: Colorless transparent liquid
Density: 1.512 g/mL at 25 °C
Molecular Formula: F6H2Zr
Molecular Weight: 205.215
Flash Point: None
Exact Mass: 203.896225
LogP: 2.74620
Stability: Stable.
Molecular Weight: 207.23 g/mol
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0
Exact Mass: 205.910768 g/mol
Monoisotopic Mass: 205.910768 g/mol
Topological Polar Surface Area: 0Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 19.1

Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Compound Formula: F6H2Zr
Molecular Weight: 207.23
Appearance: Colorless to Pale Blue or Green liquid
Melting Point: N/A
Boiling Point: N/A
Density: 1.512 g/mL
Solubility in H2O: N/A
Exact Mass: 205.910774
Monoisotopic Mass: 205.910774
Boiling point: 100℃[at 101 325 Pa]
Density: 1.512 g/mL at 25 °C
solubility: Miscible with acid-base solutions.
form: Liquid
Exposure limits ACGIH: TWA 5 mg/m3; STEL 10 mg/m3
NIOSH: IDLH 25 mg/m3; TWA 5 mg/m3; STEL 10 mg/m3
Stability: Stable.
CAS DataBase Reference: 12021-95-3(CAS DataBase Reference)
EPA Substance Registry System: Zirconate(2-), hexafluoro-, dihydrogen, (OC-6-11)- (12021-95-3)

CAS Number: 12021-95-3
EC Numberr: 234-666-0
PubChem CID: 14299283
Chemical Name: Hexafluorozirconic acid 45% w/v aqueous solution
IUPAC Name: tetrafluorozirconium;dihydrofluoride
Synonym: Dihydrogen hexafluorozirconate
InChI: InChI=1S/6FH.Zr/h6*1H;/q;;;;;;+4/p-4
InChIKey: DXIGZHYPWYIZLM-UHFFFAOYSA-J
SMILES: F.F.F[Zr](F)(F)F
MDL Number: MFCD00082965
CAS NO.: 12021-95-3
Other Name: Fluozirconic Acid, hexafluorozirconate(2-)
EINECS No.: 234-666-0
Molecula Formula(MF): H2ZrF6
HS Code: 28261990.90
Formula Weight: 207
Appearance: Colorless transparent liquid.
Physical state: liquid
Color: No data available
Odor: No data available

Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: Not applicable
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility at 20 °C: soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,512 g/mL at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: No data available



FIRST AID MEASURES of HEXAFLUOROZIRCONIC ACID (HFZA):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXAFLUOROZIRCONIC ACID (HFZA):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXAFLUOROZIRCONIC ACID (HFZA):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXAFLUOROZIRCONIC ACID (HFZA):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
required
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXAFLUOROZIRCONIC ACID (HFZA):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
*Storage class:
Storage class (TRGS 510): 6.1D:
Non-combustible



STABILITY and REACTIVITY of HEXAFLUOROZIRCONIC ACID (HFZA):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
Fluozirconic Acid
hexafluorozirconate(2-)
Dihydrogen hexafluorozirconate;
Zirconate(2-),hexafluoro-,hydrogen (1:2),(OC-6-11)-
Zirconate(2-),hexafluoro-,dihydrogen
Zirconate(2-),hexafluoro-,dihydrogen,(OC-6-11)-
Hydrogen hexafluorozirconate(IV)
Fluozirconic(IV) acid (H2ZrF6)
Dihydrogen hexafluorozirconate(2-)
Fluorozirconic acid
Hydrogen zirconium fluoride (H2ZrF6)
Hexafluorozirconium acid
Nanotex ZR 16
59597-78-3
Zirconate(2-), hexafluoro-
Hexafluorozirconic acid
Hexafluorozirconate(2-)
Hydrogen zirconium fluoride
EINECS 234-666-0
hexafluorozirconium(2-),hydron
MFCD00082965
Dihydrogen hexafluorozirconate
Hexafluorozirconic acid
tetrafluorozirconium;dihydrofluoride
Zirconate(2-), hexafluoro-, dihydrogen, (OC-6-11)-
Hexafluorzirkonsaurelosung
AKOS015903617
zirconium(IV) fluoride dihydrofluoride
FT-0627006
J-521444
Q62018152
FLUOROZIRCONIC ACID
fluorozirconic
DIHYDROGEN HEXAFLUOROZIRCONATE
Fluorozirconate
Fluorozirconate acid
Hexafluorozirconic a
Hexafluozirconic acide
HEXAFLUOROZIRCONIC ACID
Hexafluorozirconicacid98%
Fluorozirconic acid(H2ZrF6)
dihydrogen,(oc-6-11)-zirconate(2-hexafluoro-
fluorozirconic
Zirconate(2-),hexafluoro-,dihydrogen
Fluorozirconic acid
hexafluorozirconic acid solution
dihydrogen hexafluorozirconate(2-)
dihydrogen hexafluorozirconate solution
hydrogen zirconium fluoride solution
dihydrogen,(oc-6-11)-zirconate(2-hexafluoro-
fluorozirconic
Zirconate(2-),hexafluoro-,dihydrogen
DIHYDROGEN HEXAFLUOROZIRCONATE
FLUOROZIRCONIC ACID
HEXAFLUOROZIRCONIC ACID
Dihydrogen hexafluorozirconate solution
Hexafluorozirconic acid solution
Hexafluorozirconic acid solution
Dihydrogen hexafluorozirconate,
45% w/w aq., Zirconate(2-)
hexafluoro-, dihydrogen
Fluorozirconic acid
Dihydrogen hexafluorozirconate solution
Hydrogen zirconium fluoride
Zirconate(2-), hexafluoro-, hydrogen (1:2), (OC-6-11)-
Dihydrogen hexafluorozirconate solution
Hydrogen zirconium fluoride


HEXAFLUOROZIRCONIC ACID 45 %
Hexafluorozirconic acid 45 % is a colorless, odorless liquid mixture, completely soluble in water and stable under recommended storage conditions.
Hexafluorozirconic acid 45 % is corrosive to metals.
Hexafluorozirconic acid 45 % is an inorganic compound that exists in two forms: a solid and a liquid.


CAS Number: 12021-95-3
EC Number: 234-666-0
MDL Number: MFCD00082965
Molecular Formula: F6H2Zr


Hexafluorozirconic acid 45 % is a solution of dihydrogen hexafluorozirconate containing a small percentage of hydrogen fluoride and used in the phosphating process for metal plating.
Hexafluorozirconic acid 45 % is an alternative to nickel in this process because nickel is subject to environmental regulation.


Hexafluorozirconic acid 45 % reduces considerably the formation of sludge byproducts compared to zinc-phosphate-based systems and it also can be plugged into production lines easily, with little or no modifications.
Hexafluorozirconic acid 45 % is a colorless and transparent liquid, which is acidic and has a specific gravity of about 1.48.


At room temperature, when the concentration exceeds 42%, Hexafluorozirconic acid 45 % is precipitated.
Hexafluorozirconic acid 45 % is an organic compound with the formula H2ZrF6.
With the CAS registry number 12021-95-3, Hexafluorozirconic acid 45 % is also named as fluorozirconic acid.


Hexafluorozirconic acid 45 %'s category is Inorganics.
Besides, Hexafluorozirconic acid 45 % should be stored in a a cool closed and well-ventilated place.
Hexafluorozirconic acid 45 % is white or of-white powder or crystalline powder, and odorless.


Hexafluorozirconic acid 45 % is a solution of dihydrogen hexafluorozirconate containing a small percentage of hydrogen fluoride and used in the phosphating process for metal plating.
Hexafluorozirconic acid 45 % is very soluble in N,N-Dimethylformamide, Soluble in methanol, Sparingly soluble in glacial acetic acid, Very slightly soluble in chloroform, and Practically insoluble in water.


Hexafluorozirconic acid 45 % is known to have chemical formula F6H2Zr with molecular weight of 207.23 g/mol.
Hexafluorozirconic acid 45 % is a colorless and transparent liquid, which is acidic and has a specific gravity of about 1.48.
At room temperature, when the concentration exceeds 42%, Hexafluorozirconic acid 45 % is precipitated.


Hexafluorozirconic acid 45 % is a colorless liquid with a characteristic smell odor of hydrogen fluoride.
Hexafluorozirconic acid 45 % is incompatible with strong acids, bases, and should be stored away from metals as contact with metals can result in the release of hydrogen gas that can be explosive.


This mixture is predominantly composed of 45% dihydrogen hexafluorozirconate(2-), 54.5% water and hydrofluoric acid comprising approximately 0.5%.
Hexafluorozirconic acid 45 % is the preferred choice when replacing zinc-phosphate ahead of an electrocoat painting system.
Hexafluorozirconic acid 45 % is a non-flammable.


Hexafluorozirconic acid 45 % is white or of-white powder or crystalline powder, and odorless.
Hexafluorozirconic acid 45 % is also utilized in medical & pharmaceutical industries for various formulations.
Hexafluorozirconic acid 45 % is completely free from impurities and can be availed at highly competitive rates in bulk amounts.
Hexafluorozirconic acid 45 % is a light green liquid



USES and APPLICATIONS of HEXAFLUOROZIRCONIC ACID 45 %:
Hexafluorozirconic acid 45 % is used in the pre-treatment of aluminum prior to surface finishing, for example, prior to painting aluminum beverage cans, automotive surfaces and appliances.
Hexafluorozirconic acid 45 % is used in based surface pretreatments on steel for corrosion resistance.


Hexafluorozirconic acid 45 % is used Preparation of titania photocatalyst synthesized from the ionic-liquid-like precursor.
Hexafluorozirconic acid 45 % is also used in optical glass, salt manufacturing, in chromate solution can improve the corrosion resistance of steel, zinc, lead and other metals.


Hexafluorozirconic acid 45 % is used electroplating, aluminum lacquering in chrome-free processes, synthesis of fluoride-releasing dental monomers, as a precursor of ZrO2 ceramic films as well as metal surface passivation.
Hexafluorozirconic acid 45 % is used commonly in industrial settings as a precursor material for the manufacture of films used to coat ceramics, to synthesize glass used in prescription eyeglasses and as a common corrosion inhibitor on steel and other metal surfaces.


Hexafluorozirconic acid 45 % is used as precursor to ZrO2 ceramic thin films.
Hexafluorozirconic acid 45 % is used in the manufacture of optical glass and fluorozirconate.
Hexafluorozirconic acid 45 % is used for metal surface treatment and cleaning.


Hexafluorozirconic acid 45 % is used synthesis of fluoride-releasing dental monomers.
Hexafluorozirconic acid 45 % is used for Electroplating.
Hexafluorozirconic acid 45 % is used in wool, leather industry, atomic energy industry and the production of advanced electrical materials, refractories.


Hexafluorozirconic acid 45 % is used for metal surface treatment and cleaning, as well as for wool, leather garment industry, atomic energy industry and production of high-grade electrical materials and refractories.
Hexafluorozirconic acid 45 % is used for metal surface and coating.


Hexafluorozirconic acid 45 % is used for metal surface treatment and cleaning, also used in the atomic energy industry and advanced electrical materials, refractory production
Hexafluorozirconic acid 45 % is used Aluminium pre-treatment solutions chrome-free processes.


Hexafluorozirconic acid 45 % is used Metal surface treatment, Automotive, and Paint.
Hexafluorozirconic acid 45 % is a highly reactive compound that is used in a variety of scientific and industrial applications.
Hexafluorozirconic acid 45 % is primarily used as a catalyst in the synthesis of organic compounds, as a reagent in the synthesis of fluorinated compounds, and as a reagent for the production of fluorinated polymers.


Hexafluorozirconic acid 45 % is also used in the manufacture of semiconductor materials and in the production of high-strength glass.
Hexafluorozirconic acid 45 % is mainly used in metal surface treatment and cleaning
Hexafluorozirconic acid 45 %'s also used in the wool, leather industry and the atomic energy industry and advanced electrical materials, refractory production etc.


Hexafluorozirconic acid 45 % reduces the occurrence of sludge as a side product – e.g. in Zincphosphate based systems
Hexafluorozirconic acid 45 % is used for metal surface treatment and cleaning, as well as for atomic energy industry and production of advanced electrical materials and refractories.


Hexafluorozirconic acid 45 % is mainly used in manufacturing of optical glass and fluozirconate.
Hexafluorozirconic acid 45 % is used as raw materials for zirconium, magnesium alloy, catalyst, steel and non-ferrous metal alloy, as well as atomic energy industry and advanced electrical materials, refractories, electric vacuum technology materials, optical glass materials, pyrotechnics, ceramics, enamel and glass production.


Hexafluorozirconic acid 45 % is used Synthesis of fluoride-releasing dental monomer
Hexafluorozirconic acid 45 % is used as precursor to ZrO2 ceramic thin films
Hexafluorozirconic acid 45 % is used in the pre-treatment of aluminum prior to surface finishing, for example, prior to painting aluminum beverage cans, automotive surfaces and appliances.


Hexafluorozirconic acid 45 % is often used in the form of fluozirconate, as raw materials for zirconium chemical compounds, magnesium alloys, catalysts, steel and non-ferrous metal alloys, as well as atomic energy industry and advanced electrical materials, refractory materials, electrical vacuum technology materials, optical glass Raw materials, pyrotechnics, ceramics, etc.


Hexafluorozirconic acid 45 % is also used in optical glass, zirconium fluoride acid salt manufacturing, in chromate solution can improve the corrosion resistance of steel, zinc, lead and other metals.
Hexafluorozirconic acid 45 % is used as a precursor to ZrO2 ceramic thin films.


Hexafluorozirconic acid 45 % finds most common application for preparation of photocatalysts, titanium dioxide, & thin films of zirconium oxide.
Hexafluorozirconic acid 45 % can be used for metal surface preparation and cleaning.
Hexafluorozirconic acid 45 % is also used for treatment of metal's surface so as to improve its properties.


Uses of Hexafluorozirconic acid 45 %: Surface treatment; Electroplating; Aluminium lacquering in chrome-free processes. Metal Industry; Corrosion inhibitor in surface pre-treatment (aluminium and other metals).
Hexafluorozirconic acid 45 % is also used in wool, leather garment industry, atomic energy industry and production of advanced electrical materials and refractory materials.


Hexafluorozirconic acid 45 % can be used for surface pretreatments on steel for corrosion resistance.
Hexafluorozirconic acid 45 % is used Surface treatment; Electroplating; Aluminium lacquering in chrome-free processes.
Metal Industry uses of Hexafluorozirconic acid 45 %; Corrosion inhibitor in surface pre-treatment (aluminium and other metals).


Hexafluorozirconic acid 45 % is used for the production of the atomic energy industry, advanced electrical materials and refractories.
Hexafluorozirconic acid 45 % does show highest effectiveness on aluminium though it can be used on other metals as well.
Hexafluorozirconic acid 45 % is mainly used as corrosion inhibitor by customers active in the metal and coatings industry.


Hexafluorozirconic acid 45 % is often used in the form of fluozirconate, as raw materials for zirconium chemical compounds, magnesium alloys, catalysts, steel and non-ferrous metal alloys, as well as atomic energy industry and advanced electrical materials, refractory materials, electrical vacuum technology materials, optical glass Raw materials, pyrotechnics, ceramics, etc.


Hexafluorozirconic acid 45 % is used in manufacturing of optical glass and fluozirconate.
Hexafluorozirconic acid 45 % has multiple uses in inorganic chemical reactions such as the preparation of titanium oxide photocatalysts and zirconium oxide thin films.


Hexafluorozirconic acid 45 % is mainly used as corrosion inhibitor by customers active in the metal and coatings industry.
Hexafluorozirconic acid 45 % acts as a precursor to zirconium dioxide ceramic thin films.
Further, Hexafluorozirconic acid 45 % is used for surface pretreatments on steel to prevent corrosion.


In addition to this, Hexafluorozirconic acid 45 % is used in the production of the atomic energy industry, advanced electrical materials and refractories.
American Elements can produce most materials in high purity and ultra high purity (up to 99.99999%) forms and follows applicable ASTM testing standards; a range of grades are available including Mil Spec (military grade), ACS, Reagent and Technical Grade, Food, Agricultural and Pharmaceutical Grade, Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia).


Hexafluorozirconic acid 45 % is mainly used in manufacturing of optical glass and fluozirconate.
Hexafluorozirconic acid 45 % is used in based surface pretreatments on steel for corrosion resistance
Hexafluorozirconic acid 45 % is used Preparation of titania photocatalyst synthesized from ionic-liquid-like precursor.
Hexafluorozirconic acid 45 % does show highest effectiveness on aluminium though it can be used on other metals as well.


-Hexafluorozirconic acid 45 % is used:
*electroplating
*aluminum lacquering in chrome-free processes
*synthesis of fluoride releasing dental monomers, as a precursor of ZrO2 ceramic films as well as metal surface passivation
*Hexafluorozirconic acid reduces the occurrence of sludge as a side product – e.g. in Zincphosphate based systems



FEATURES OF HEXAFLUOROZIRCONIC ACID 45 %:
*Optimum quality
*Accurate composition
*Long shelf life



FUNCTION OF HEXAFLUOROZIRCONIC ACID 45 %:
* Hexafluorozirconic acid 45 % is used for the manufacture of optical glass and fluorozirconate.
* Hexafluorozirconic acid 45 % is used for metal surface treatment and cleaning, also used in wool, leather garment industry, atomic energy industry and production of advanced electrical materials and refractory materials
* Hexafluorozirconic acid 45 % is used for metal surfaces and coatings, etc.



SYNTHESIS METHOD OF HEXAFLUOROZIRCONIC ACID 45 %:
Hexafluorozirconic acid 45 % can be synthesized in a number of ways, including the reaction of zirconium dioxide with hydrogen fluoride, the reaction of zirconium oxychloride with hydrofluoric acid, and the reaction of zirconium tetrachloride with hydrofluoric acid.
The reaction of zirconium dioxide with hydrogen fluoride is the most commonly used method of synthesis.
In this method, zirconium dioxide is reacted with hydrogen fluoride in an aqueous solution at a temperature of approximately 70°C.
The reaction produces Hexafluorozirconic acid 45 %, which is then isolated and purified by distillation.



SYNTHESIS METHOD DETAILS OF HEXAFLUOROZIRCONIC ACID 45 %:
Design of the Synthesis Pathway
The synthesis of Hexafluorozirconic acid 45 % can be achieved through the reaction of Zirconium(IV) oxide with Hydrogen fluoride gas.
Starting Materials:
Zirconium(IV) oxide, Hydrogen fluoride gas



REACTION OF HEXAFLUOROZIRCONIC ACID 45 %:
Zirconium(IV) oxide is added to a reaction vessel, and Hydrogen fluoride gas is introduced into the reaction vessel.
The reaction mixture is heated to a temperature of 150-200°C.
The reaction proceeds to form Hexafluorozirconic acid 45 %.
The Hexafluorozirconic acid 45 % is then purified through distillation or precipitation methods



SCIENTIFIC RESEARCH APPLICATION OF HEXAFLUOROZIRCONIC ACID 45 %:
Hexafluorozirconic acid 45 % is used in a variety of scientific research applications, including the synthesis of organic compounds, the synthesis of fluorinated compounds, and the production of fluorinated polymers.
Hexafluorozirconic acid 45 % is also used in the production of semiconductor materials and in the manufacture of high-strength glass.
In addition, Hexafluorozirconic acid 45 % is used as a reagent in the synthesis of organometallic compounds and in the production of high-performance polymers.



MECHANISM OF ACTION OF HEXAFLUOROZIRCONIC ACID 45 %:
The mechanism of action of Hexafluorozirconic acid 45 % is not fully understood.
It is believed that Hexafluorozirconic acid 45 % acts as a Lewis acid, which means that it can form a bond with an electron-rich species, such as a Lewis base.
This bond can then be used to catalyze the formation of a new bond between two molecules.
Additionally, Hexafluorozirconic acid 45 % can act as a nucleophile, which means that it can react with electron-deficient species, such as electrophiles.



PHYSICAL and CHEMICAL PROPERTIES of HEXAFLUOROZIRCONIC ACID 45 %:
CAS Number: 12021-95-3
EC Numberr: 234-666-0
PubChem CID: 14299283
Chemical Name: Hexafluorozirconic acid 45% w/v aqueous solution
IUPAC Name: tetrafluorozirconium;dihydrofluoride
Synonym: Dihydrogen hexafluorozirconate
InChI: InChI=1S/6FH.Zr/h6*1H;/q;;;;;;+4/p-4
InChIKey: DXIGZHYPWYIZLM-UHFFFAOYSA-J
SMILES: F.F.F[Zr](F)(F)F
MDL Number: MFCD00082965
CAS NO.: 12021-95-3
Other Name: Fluozirconic Acid, hexafluorozirconate(2-)
EINECS No.: 234-666-0
Molecula Formula(MF): H2ZrF6
HS Code: 28261990.90
Formula Weight: 207
Appearance: Colorless transparent liquid.
Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: Not applicable
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility at 20 °C: soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,512 g/mL at 25 °C

Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: No data available
Molecular Weight: 207.23000
Exact Mass: 205.91100
XLogP3: 2.74620
Appearance: Clear Colourless solution
Density: 1.52
Flash Point: None
CAS No.: 12021-95-3
Molecular Formula: F4Zr.2FH
Molecular weight: 207.23
Appearance: Colorless transparent liquid
Density: 1.512 g/mL at 25 °C
Molecular Formula: F6H2Zr
Molecular Weight: 205.215
Flash Point: None
Exact Mass: 203.896225
LogP: 2.74620
Stability: Stable.
Molecular Weight: 207.23 g/mol
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0
Exact Mass: 205.910768 g/mol
Monoisotopic Mass: 205.910768 g/mol

Topological Polar Surface Area: 0Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 19.1
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Compound Formula: F6H2Zr
Molecular Weight: 207.23
Appearance: Colorless to Pale Blue or Green liquid
Melting Point: N/A
Boiling Point: N/A
Density: 1.512 g/mL
Solubility in H2O: N/A
Exact Mass: 205.910774
Monoisotopic Mass: 205.910774
Boiling point: 100℃[at 101 325 Pa]
Density: 1.512 g/mL at 25 °C
solubility: Miscible with acid-base solutions.
form: Liquid
Exposure limits ACGIH: TWA 5 mg/m3; STEL 10 mg/m3
NIOSH: IDLH 25 mg/m3; TWA 5 mg/m3; STEL 10 mg/m3
Stability: Stable.
CAS DataBase Reference: 12021-95-3(CAS DataBase Reference)
EPA Substance Registry System: Zirconate(2-), hexafluoro-, dihydrogen, (OC-6-11)- (12021-95-3)



FIRST AID MEASURES of HEXAFLUOROZIRCONIC ACID 45 %:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXAFLUOROZIRCONIC ACID 45 %:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.




FIRE FIGHTING MEASURES of HEXAFLUOROZIRCONIC ACID 45 %:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXAFLUOROZIRCONIC ACID 45 %:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
required
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXAFLUOROZIRCONIC ACID 45 %:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only
to qualified or authorized persons.
*Storage class:
Storage class (TRGS 510): 6.1D:
Non-combustible



STABILITY and REACTIVITY of HEXAFLUOROZIRCONIC ACID 45 %:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
Hexafluorozirconic acid solution
Dihydrogen hexafluorozirconate,
45% w/w aq., Zirconate(2-)
hexafluoro-, dihydrogen
Fluorozirconic acid
Dihydrogen hexafluorozirconate solution
Hydrogen zirconium fluoride
Zirconate(2-), hexafluoro-, hydrogen (1:2), (OC-6-11)-
Dihydrogen hexafluorozirconate solution
Hydrogen zirconium fluoride
Fluozirconic Acid
hexafluorozirconate(2-)
Dihydrogen hexafluorozirconate;
Zirconate(2-),hexafluoro-,hydrogen (1:2),(OC-6-11)-
Zirconate(2-),hexafluoro-,dihydrogen
Zirconate(2-),hexafluoro-,dihydrogen,(OC-6-11)-
Hydrogen hexafluorozirconate(IV)
Fluozirconic(IV) acid (H2ZrF6)
Dihydrogen hexafluorozirconate(2-)
Fluorozirconic acid
Hydrogen zirconium fluoride (H2ZrF6)
Hexafluorozirconium acid
Nanotex ZR 16
59597-78-3
Zirconate(2-), hexafluoro-
Hexafluorozirconic acid
Hexafluorozirconate(2-)
Hydrogen zirconium fluoride
EINECS 234-666-0
hexafluorozirconium(2-),hydron
MFCD00082965
Dihydrogen hexafluorozirconate
Hexafluorozirconic acid
tetrafluorozirconium;dihydrofluoride
Zirconate(2-), hexafluoro-, dihydrogen, (OC-6-11)-
Hexafluorzirkonsaurelosung
AKOS015903617
zirconium(IV) fluoride dihydrofluoride
FT-0627006
J-521444
Q62018152
FLUOROZIRCONIC ACID
fluorozirconic
DIHYDROGEN HEXAFLUOROZIRCONATE
Fluorozirconate
Fluorozirconate acid
Hexafluorozirconic a
Hexafluozirconic acide
HEXAFLUOROZIRCONIC ACID
Hexafluorozirconicacid98%
Fluorozirconic acid(H2ZrF6)
dihydrogen,(oc-6-11)-zirconate(2-hexafluoro-
fluorozirconic
Zirconate(2-),hexafluoro-,dihydrogen
Fluorozirconic acid
hexafluorozirconic acid solution
dihydrogen hexafluorozirconate(2-)
dihydrogen hexafluorozirconate solution
hydrogen zirconium fluoride solution
dihydrogen,(oc-6-11)-zirconate(2-hexafluoro-
fluorozirconic
Zirconate(2-),hexafluoro-,dihydrogen
DIHYDROGEN HEXAFLUOROZIRCONATE
FLUOROZIRCONIC ACID
HEXAFLUOROZIRCONIC ACID
Dihydrogen hexafluorozirconate solution
Hexafluorozirconic acid solution


HEXAHYDROANILINE
DESCRIPTION:

Hexahydroaniline is an organic compound, belonging to the aliphatic amine class.
Hexahydroaniline is a colorless liquid, although, like many amines, samples are often colored due to contaminants.
Hexahydroaniline has a fishy odor and is miscible with water.



CAS NUMBER: 108-91-8

EC NUMBER: 203-629-0

MOLECULAR FORMULA: C6H13N

MOLECULAR WEIGHT: 99.1741




DESCRIPTION:

Like other amines, Hexahydroaniline is a weak base, compared to strong bases such as NaOH, but it is a stronger base than its aromatic analog, aniline.
Hexahydroaniline, also known as cyclohexylamine, is an organic compound with the chemical formula C6H13NH2.
Hexahydroaniline is a cyclic aliphatic amine derived from cyclohexane.
Hexahydroaniline consists of a six-membered ring of carbon atoms with an amino group (-NH2) attached to one of the carbon atoms.

Hexahydroaniline is a colorless liquid with a strong, ammonia-like odor.
Hexahydroaniline is soluble in water and many organic solvents.
Hexahydroaniline is primarily used as an intermediate in the production of various chemicals, including pharmaceuticals, agricultural chemicals, and rubber chemicals.
Hexahydroaniline is also used as a corrosion inhibitor, a solvent in the synthesis of dyes and resins, and as a stabilizer in the synthesis of polyurethanes.
Hexahydroaniline is a moderately hazardous substance, and proper safety precautions should be taken when handling it.

Hexahydroaniline is a useful intermediate in the production of many other organic compounds (e.g. cyclamate)
Hexahydroaniline is typically used as an intermediate in synthesis for different herbicides, antioxidants and pharmaceuticals.
Hexahydroaniline is clear colorless to pale yellow liquid with an amine-like odor, no visible impurities.
Hexahydroaniline is a strong organic caustic liquid.
Hexahydroaniline can form azeotrope with water at 96.40°C.

Hexahydroaniline is miscible with water and all common organic solvents.
Hexahydroaniline is mainly used for producing (Beet) molasses, cyclone, amide, nylon 6,cellulose acetate and rubber accelerator, sweetening agent, the agent for preventing corrode, emulsion, antiseptic, antistatic agent, latex cement, oil additive, germicide, pesticide and dyestuff medium, etc.
Hexahydroaniline appears as a clear colorless to yellow liquid with an odor of ammonia.
Flash point is 90 °F.

Hexahydroaniline has less dense than water.
Hexahydroaniline's vapor is heavier than air.
Hexahydroaniline is a primary aliphatic amine consisting of cyclohexane carrying an amino substituent.
Hexahydroaniline has a role as a human xenobiotic metabolite and a mouse metabolite.
Hexahydroaniline is a conjugate base of a cyclohexylammonium.

Hexahydroaniline is the six-membered alicyclic hydrocarbon consisting of six carbon atoms linked to each other to form a ring, with each carbon atom bearing two hydrogen atoms, C6H12.
Hexahydroaniline is an organic compound that contains one or more closed rings of carbon atoms.
Hexahydroaniline is a colorless, highly flammable, mobile liquid with a pungent odor.

Hexahydroaniline is insoluble in water and soluble in alcohol, ether, and almost organic solvents.
Hexahydroaniline is a non-corrosive and quick volatilize liquid and sublimes between -5 to 5 C.
Hexahydroaniline can exist in a number of interconvertible three-dimensional conformations, the two simplest being are the chair and boat conformation and others include the half-chair and twist-chair conformation.

Hexahydroaniline can cause irritation to the eyes and mucous membranes in workers.
Repeated and prolonged contact with skin may cause dermatitis.
Hexahydroaniline has not been shown to cause the hematologic changes associated with exposure to benzene.
Hexahydroaniline occurs naturally in crude oils.

Hexahydroaniline is recovered from petroleum streams by fractionation.
The bulky commercial production of Hexahydroaniline is based on hydrogenation of benzene in closed system.
Hexahydroaniline is linked almost entirely to nylon production.
Hexahydroaniline is used as a solvent, oil extractant, paint and varnish remover, dry cleaning material, and in solid fuels.
Hexahydroaniline has been used as a insecticide itself.

Hexahydroaniline is used as a chemical intermediate to produce target molecules.
Natural compounds of one to five alicyclic rings with great variety and complexity are found particularly in steroids and terpenes.
Hexahydroaniline structure, six membered-ring, is one of the major skeleton in nature.
Hexahydroaniline derivatives can be used for the synthesis of pharmaceuticals, dyes, herbicides, plant growth regulator, plasticizers, rubber chemicals, cycloamines and other organic compounds.
Hexahydroaniline is a colorless liquid.

Hexahydroaniline is used as a precursor to prepare corrosion inhibitors, desulfurizers, antistatic agents, vulcanization accelerators, food additive sweeteners, emulsifiers, latex coagulants, petroleum product additives, fungicides, and insecticides.
Hexahydroaniline is used as a solvent in the synthesis of an inorganic-organic hybrid semiconductor, and nanocomposites.
Hexahydroaniline is mainly used as an intermediate for organic synthesis, especially for herbicides, antioxidants & vulcanization accelerator, corrosion inhibitors and artificial sweetener.




USAGE:

Hexahydroaniline is an important organic chemical raw material.
Hexahydroaniline is mainly used as an intermediate for organic synthesis, especially for herbicides, antioxidants&vulcanization accelerator, corrosion inhibitors, artificial sweetener etc.
Hexahydroaniline is also used to make rubber accelerator CZ and sweet-element.
Additionally, Hexahydroaniline also can be used to make cyclohexanol, cyclohexanone, emulsifying agent, preservative, antistatic agent, gelling agent, and petroleum additive.
Hexahydroaniline has several usage areas in various industries.
Some of the common applications of hexahydroaniline include:


-Chemical Intermediates:

Hexahydroaniline is widely used as an intermediate in the production of various chemicals.
Hexahydroaniline serves as a building block in the synthesis of pharmaceuticals, agrochemicals, and rubber chemicals.
Hexahydroaniline can undergo further reactions to create a variety of compounds with diverse applications.


-Corrosion Inhibitors:

Hexahydroaniline is employed as a corrosion inhibitor to protect metals from rust and corrosion.
Hexahydroaniline can be added to cooling water systems, metal cleaning solutions, and oil field equipment to prevent or minimize the damage caused by corrosive substances.


-Solvent and Diluent:

Hexahydroaniline is used as a solvent and diluent in different industries.
Hexahydroaniline can dissolve a range of substances, making it suitable for applications such as paint and coating formulations, ink production, and the synthesis of dyes and resins.


-Rubber Industry:

Hexahydroaniline is utilized in the rubber industry as an accelerator or activator in the vulcanization process of rubber.
Hexahydroaniline aids in the cross-linking of rubber molecules, improving the strength, elasticity, and durability of rubber products.


-Polyurethane Production:

Hexahydroaniline is employed as a stabilizer or chain extender in the synthesis of polyurethanes.
Hexahydroaniline helps control the reaction rate, molecular weight, and properties of the polyurethane polymers.
Polyurethanes find applications in various industries, including automotive, construction, furniture, and textiles.


-Pharmaceutical Industry:

Hexahydroaniline is utilized as an intermediate in the production of pharmaceuticals.
Hexahydroaniline can be involved in the synthesis of active pharmaceutical ingredients (APIs) and other important pharmaceutical compounds.
Hexahydroaniline's important to note that the specific usage and applications of hexahydroaniline can vary depending on the industry and intended purpose.
Hexahydroaniline should be handled and used in accordance with safety guidelines and appropriate precautions.




APPLICATIONS:

Hexahydroaniline is used as an intermediate in synthesis of other organic compounds.
Hexahydroaniline is the precursor to sulfenamide-based reagents used as accelerators for vulcanization.
Hexahydroaniline is a building block for pharmaceuticals (e.g., mucolytics, analgesics, and bronchodilators).
The amine itself is an effective corrosion inhibitor.
The herbicide hexazinone and the anesthetic hexylcaine are derived from cyclohexylamine.
Hexahydroaniline has been used as a flushing aid in the printing ink industry.



APPLICATION AREAS:

-electronic chemical
-solder flux activator




PREPARATION:

Hexahydroaniline is produced by two routes, the main one being the complete hydrogenation of aniline using some cobalt- or nickel-based catalysts:

C6H5NH2 + 3 H2 → C6H11NH2

Hexahydroaniline is also prepared by alkylation of ammonia using cyclohexanol.



SPECIFICATIONS:

-Appearance: Colorless or light yellow transparent liquid; no visible impurities
-Cyclohexylamine: ≥99.5%
-Aniline: ≤0.10%
-Dicyclohexylamine: ≤0.10%
-Moisture: ≤0.20%



SPECIFICATIONS:

-Melting Point: -17.0°C
-Density: 0.8665g/mL
-Boiling Point: 133.0°C to 134.0°C
-Flash Point: 27°C
-Infrared Spectrum: Authentic
-Assay Percent Range: 98.5% min. (GC)
-Linear Formula: C6H11NH2
-Refractive Index: 1.4580 to 1.4600
-Viscosity: 2.4 mPa.s (20°C)
-Formula Weight: 99.18
-Percent Purity: 99%
-Physical Form: Liquid
-Chemical Name or Material: Cyclohexylamine



PROPERTIES:

-Molecular Weight: 99.17 g/mol
-XLogP3: 1.5
-Hydrogen Bond Donor Count: 1
-Hydrogen Bond Acceptor Count: 1
-Rotatable Bond Count: 0
-Exact Mass: 99.104799419 g/mol
-Monoisotopic Mass: 99.104799419 g/mol
-Topological Polar Surface Area: 26Ų
-Heavy Atom Count: 7
-Complexity: 46.1
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 0
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes



PHYSICAL AND CHEMICAL PROPERTIES:

-PHYSICAL STATE: Clear to yellow liquid with fishy odor
-MELTING POINT: -17.5 C
-BOILING POINT: 134.5 C
-SPECIFIC GRAVITY: 0.86
-SOLUBILITY IN WATER: miscible (1.00E+06 mg/l at 20 C)
-pH: 10.5
-VAPOR DENSITY: 3.42
-log Pow: 1.49 (Octanol-water)
-VAPOR PRESSURE: 10.1 (mmHg at 25 C)
-HENRY'S LAW: 4.16E-06 (atm-m3/mole at 25 C)
-OH RATE: 5.54E-11 (cm3/molecule-sec at 25 C Atmospheric )
-AUTOIGNITION: 560 C
-NFPA RATINGS: Health: 3; Flammability: 3; Reactivity: 0
-REFRACTIVE INDEX: 1.4565
-FLASH POINT: 28.5 C
-STABILITY: Stable under ordinary conditions



STORAGE:

Store in cool, dry and airiness place; far away from fire and heat, toxic chemicals.



SYNONYM:

hexahydro-anilin
cyclohexyl-amine
cyclohexaneamine
AMINOCYCLOHEXANE
monocyclohexyl amine
1-Aminocyclohexane
NH2-cyclo-C6H11
CHA
Cyclohexylamin
CHA-60
Cyclohexylamine
Cyclohexanamine
Cyclohexanamine
108-91-8
Aminocyclohexane
Hexahydroaniline
Hexahydrobenzenamine
Aminohexahydrobenzene
1-Cyclohexylamine
Cyclohexyl amine
1-Aminocyclohexane
Aniline, hexahydro-
Benzenamine, hexahydro-
Aminocylcohexane
cyclohexyl-amine
CCRIS 3645
HSDB 918
UNII-I6GH4W7AEG
1-AMINO-CYCLOHEXANE
cyclohexaneamine
I6GH4W7AEG
monocyclohexylamine
EINECS 203-629-0
BRN 0471175
DTXSID1023996
CHEBI:15773
AI3-15323
Cyclohexylamine.HCl
UN2357
157973-60-9
DTXCID203996
EC 203-629-0
4-12-00-00008 (Beilstein Handbook Reference)
MFCD00001486
Cyclohexylamine [UN2357] [Corrosive]
Cyclohexylamine [UN2357] [Corrosive]
CAS-108-91-8
HAI
GLIPIZIDE IMPURITY B (EP IMPURITY)
GLIPIZIDE IMPURITY B [EP IMPURITY]
cyclohexanamin
cylohexylamine
Ciclohexanamina
Ciclohexilamina
Sykloheksylamin
cyclohexylarnine
cyclo-hexylamine
cyclohexane-amine
n-cyclohexylamine
cyclohexanyl amine
Hexahydro-Aniline
4-Cyclohexylamine
Cyclohexylamine,(S)
Hexahydro-Benzenamine
Cyclohexanamine, 9CI
CyNH2
CHA (CHRIS Code)
Cyclohexylamine, 99.5%
bmse000451
D07KVF
CYCLOHEXYLAMINE [MI]
BIDD:ER0290
CYCLOHEXYLAMINE [HSDB]
CYCLOHEXYLAMINE [INCI]
GTPL5507
CHEMBL1794762
BDBM81970
Cyclohexylamine [Cyclohexanamine]
BCP30928
Tox21_202380
Tox21_300038
LS-473
NA2357
STK387114
AKOS000119083
Cyclohexylamine, ReagentPlus(R), 99%
UN 2357
VS-0326
Aminocyclohexane pound>>Hexahydroaniline
NCGC00247889-01
NCGC00247889-02
NCGC00253922-01
NCGC00259929-01
AM802905
BP-21278
CAS_108-91-8
NCI60_004907
Cyclohexylamine 1000 microg/mL in Methanol
Cyclohexylamine, ReagentPlus(R), >=99.9%
FT-0624217
EN300-16958
C00571
J-002206
J-520164
Q1147539
F2190-0381





















HEXAHYDROPHTALIC ANHYDRIDE
Hexahydrophtalic Anhydrade consists of a ring structure of cyclohexane to which two carboxylic acid groups are attached.
Hexahydrophtalic Anhydrade is a glassy solid.


CAS Number: 85-42-7
EC Number: 201-604-9
MDL number: MFCD00005926
Molecular Formula: C8H10O3


Hexahydrophtalic Anhydrade is dry powder or solid in various forms, or clear, colorless, viscous liquid.
Hexahydrophtalic Anhydrade is only slightly soluble in water, but reacts slowly on contact with it to form hexahydrophthalic acid.
Dry storage is therefore required.


Hexahydrophtalic Anhydrade is readily soluble in various organic solvents such as acetone, ethanol, benzene or chloroform.
Hexahydrophtalic Anhydrade has high-temperature stability, excellent dielectric properties, and high glass transition temperatures.
Hexahydrophtalic Anhydrade consists of a ring structure of cyclohexane to which two carboxylic acid groups are attached.


These are located on adjacent carbon atoms of the cyclohexane, are connected via an oxygen atom and together form an anhydride.
Hexahydrophtalic Anhydrade can be formed from this by absorbing a water molecule.
The double functional group results in the reactivity of Hexahydrophtalic Anhydrade and its suitability as a comonomer for polymerizations.


Hexahydrophtalic Anhydrade is a glassy solid.
Hexahydrophtalic Anhydrade is a glassy solid.
At room temperature, Hexahydrophtalic Anhydrade is already close to its melting point and can therefore easily be processed as a melt or liquid.


Hexahydrophtalic Anhydrade is colorless and odorless.
Hexahydrophtalic Anhydrade fumes are heavier than air and may spread along floors.
Hexahydrophtalic Anhydrade reacts with strong acids, bases, oxidizing agents, amines and alcohols, generating a lot of heat.


Hexahydrophtalic Anhydrade attacks iron and reacts with it to form self-igniting iron phthalate.
Hexahydrophtalic Anhydrade is flammable, but not explosive.
When heated and burned, Hexahydrophtalic Anhydrade decomposes into hazardous gases such as carbon monoxide and carbon dioxide.


Hexahydrophtalic Anhydrade is a saturated dicarboxylic anhydride and will undergo most of the reactions typical of this class of compounds.
Hexahydrophtalic Anhydrade is supplied as a white low-melting solid (38°C) which is miscible with most organic solvents.
In water, Hexahydrophtalic Anhydrade hydrolyzes to hexahydrophthalic acid.


Hexahydrophtalic Anhydrade is a very effective curing agent for epoxy resins.
Hexahydrophtalic Anhydrade belongs to a group of organic compounds called acid anhydrides.
In component epoxy resins, they serve as hardeners, which bind covalently to 2 molecules, allowing polymerisation.


Hexahydrophtalic Anhydrade is a cyclic dicarboxylic anhydride that is the cyclic anhydride of hexahydrophthalic acid.
Hexahydrophtalic Anhydrade has a role as an allergen.
Hexahydrophtalic Anhydrade is a cyclic dicarboxylic anhydride and a tetrahydrofurandione.


Hexahydrophtalic Anhydrade is stored in a dark and dry place at room temperature.
Hexahydrophtalic Anhydrade is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.


Instead, Hexahydrophtalic Anhydrade is produced from phthalic anhydride by a nuclear hydrogenation.
The addition of six hydrogen atoms in this reaction gives Hexahydrophtalic Anhydrade its name.
Hexahydrophtalic Anhydrade is a cyclic dicarboxylic anhydride that is the cyclic anhydride of hexahydrophthalic acid.


Hexahydrophtalic Anhydrade has a role as an allergen.
Hexahydrophtalic Anhydrade is a cyclic dicarboxylic anhydride and a tetrahydrofurandione.
Hexahydrophtalic Anhydrade is white crystalline powder.


Hexahydrophtalic Anhydrade is a cyclic dicarboxylic anhydride that is the cyclic anhydride of hexahydrophthalic acid.
Hexahydrophtalic Anhydrade is a cyclic anhydride that can be used for a variety of applications such as: plasticizer, rust inhibitor, and a curing agent for epoxy based resins.
Hexahydrophtalic Anhydrade is non flammable.



USES and APPLICATIONS of HEXAHYDROPHTALIC ANHYDRIDE:
Hexahydrophtalic Anhydrade is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Hexahydrophtalic Anhydrade is used in the following products: coating products and polymers.
Hexahydrophtalic Anhydrade is used for the manufacture of: machinery and vehicles.


Other release to the environment of Hexahydrophtalic Anhydrade is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).
Hexahydrophtalic Anhydrade is used in the following products: polymers.


Release to the environment of Hexahydrophtalic Anhydrade can occur from industrial use: formulation of mixtures and as processing aid.
Hexahydrophtalic Anhydrade is used in the following products: polymers and coating products.
Hexahydrophtalic Anhydrade is used in the following areas: formulation of mixtures and/or re-packaging.


Hexahydrophtalic Anhydrade is used for the manufacture of chemicals.
Release to the environment of Hexahydrophtalic Anhydrade can occur from industrial use: for thermoplastic manufacture, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.


Release to the environment of Hexahydrophtalic Anhydrade can occur from industrial use: manufacturing of the substance.
Hexahydrophtalic Anhydrade is used when maximum resistance to yellowing and premium optical and electrical performance are required.
Hexahydrophtalic Anhydrade is mainly used in the chemical industry as a monomer for polymerization processes.


Hexahydrophtalic Anhydrade is used anhydride curing agent, coating, epoxy curing agent, polyester resin, adhesive, plasticizer, antirust intermediate; epoxy curing agent, raw material of polyurethane / polyester resin for coating; organic raw material; organic chemical raw material; chemical raw material; raw material; functional additive chemical raw material


Hexahydrophtalic Anhydrade is widely used in the production and processing of plastics, paints and fine chemicals, and in the manufacture of electrical machines.
Hexahydrophtalic Anhydrade belongs to the cyclic carboxylic acid anhydrides.


However, Hexahydrophtalic Anhydrade is not usually the direct result of dehydration of the corresponding carboxylic acid.
Hexahydrophtalic Anhydrade is used as a starting material for the manufacture of polyester resins, binders and paints.
Among other things, Hexahydrophtalic Anhydrade contributes to greater weather resistance of the polymerization product and better resistance to UV light.


Hexahydrophtalic Anhydrade is compared to phthalic anhydride and isophthalic acid, which are cheaper to produce, the compound also causes the polymers produced to have a lower viscosity.
Application examples of Hexahydrophtalic Anhydrade: Production of polyester resins, binders and paints, use as anhydride for curing epoxy resins, raw material for PVC plasticizers, intermediate product for alkyd resins and rust inhibitors


Hexahydrophtalic Anhydrade is mainly used as an intermediate for coating resins (alkyds, polyesters), plasticizers, sealant, curing agent in adhesive, insect repellents, rust inhibitors, electronics applications.
Hexahydrophtalic Anhydrade’s low melt viscosity, as well as its high mix ratio with epoxy resins, makes it particularly suitable as hardener for epoxy resin for applications where high filler loadings are required.


Hexahydrophtalic Anhydrade is preferred over other aromatic anhydrides in casting and coating applications for his higher resistance to yellowing.
Hexahydrophtalic Anhydrade is also used in the preparation of alkyd and polyester resins where good color stability is important.
Hexahydrophtalic Anhydrade cured epoxies are characterized by reduced color and improved electrical and physical properties as compared to amine-cured products.


The low melting point of Hexahydrophtalic Anhydrade allows it to be easily handled and blended with liquid resins.
Viscosities of the Hexahydrophtalic Anhydrade-epoxy mixtures are lower, pot life is extended in the absence of catalyst and curing reaction is less exothermic than with other hardeners.


Areas of application of Hexahydrophtalic Anhydrade including casting, laminating, embedding, coating, and impregnating electrical components.
Hexahydrophtalic Anhydrade is widely used for electronics applications, e.g.
Hexahydrophtalic Anhydrade cured epoxy resins have excellent dielectric properties, high-temperature stability, and high glass transition temperatures.


Hexahydrophtalic Anhydrade is used as a curing agent in adhesive coatings and sealant materials, e.g. for the second-generation two-part epoxy adhesive synthesis.
Hexahydrophtalic Anhydrade is also used in the manufacture of alkyd and polyester resins, insecticides, and rust preventives.


Hexahydrophtalic Anhydrade is used Intermediate for alkyds, plasticizers, insect repellents, and rust inhibitors; hardener in epoxy resins.
Hexahydrophtalic Anhydrade, in combination with triethaylamine (TEA), can be used as a polymerization initiator in the preparation of polyester based resins.


Hexahydrophtalic Anhydrade can also be used as a hardener to cure 1,4-butanediol diglycidyl ether which can be used as an epoxy based system for electronic devices.
Predominantly Hexahydrophtalic Anhydrade is a cyclic anhydride that can be used for a variety of applications such as: plasticizer, rust inhibitor, and a curing agent for epoxy based resins.


Hexahydrophtalic Anhydrade, in combination with triethaylamine (TEA), can be used as a polymerization initiator in the preparation of polyester based resins.
Hexahydrophtalic Anhydrade can also be used as a hardener to cure 1,4-butanediol diglycidyl ether which can be used as an epoxy based system for electronic devices.



SYNTHESIS OF HEXAHYDROPHTALIC ANHYDRIDE:
Hexahydrophtalic Anhydrade is obtained by reacting ciscyclohexane-1, 2-dicarboxylic acid with oxalyl chloride.
Combine ciscyclohexane-1, 2-dicarboxylic acid (1 mmol, 172 mg) and oxalyl chloride (1.2 mmol, 152 mg, 0.103 ml) in dry toluene (5 mL) and add a drop of freshly distilled DMF.
Purge the reaction vessel with argon and heat the reaction under stirring for 3 h.
Stop the stirring, decant the toluene solution and filter.
Evaporate the volatiles.
Transform into crystalline form by trituration with diethyl ether.



PHYSICAL and CHEMICAL PROPERTIES of HEXAHYDROPHTALIC ANHYDRIDE:
Molecular Weight: 154.16 g/mol
XLogP3-AA: 1.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 0
Exact Mass: 154.062994177 g/mol
Monoisotopic Mass: 154.062994177 g/mol
Topological Polar Surface Area: 43.4Ų
Heavy Atom Count: 11
Formal Charge: 0
Complexity: 187
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

CAS Number: 85-42-7
Molecular Weight: 154.16
EC Number: 201-604-9
MDL number: MFCD00005926
Physical state: solid
Color: white
Odor: aromatic
Melting point/freezing point:
Melting point/range: 32 - 34 °C - lit.
Initial boiling point and boiling range: 158 °C at 23 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 4,2 g/l at 20 °C soluble
Partition coefficient: n-octanol/water
log Pow: 1,59 at 40 °C
Vapor pressure: 0,77 hPa at 20 °C
Density: 1,191 g/cm3 at 40 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

CBNumber:CB7468504
Molecular Formula:C8H10O3
Molecular Weight:154.16
MDL Number:MFCD00064863
MOL File:85-42-7.mol
Melting point: 32-34 °C(lit.)
Boiling point: 158 °C17 mm Hg(lit.)
Density: 1.18
vapor pressure: 0.31Pa at 25℃
refractive index: 1.4620 (estimate)
RTECS: NP6895168
Flash point: >230 °F
storage temp.: Store below +30°C.
solubility: Chloroform, Methanol (Slightly)
form: Solid
pka: 4.14[at 20 ℃]
color: White to Off-White
Water Solubility: 4.2g/L at 20℃

Sensitive: Moisture Sensitive
BRN: 83213
Exposure limits ACGIH: Ceiling 0.005 mg/m3
Stability: Moisture Sensitive
LogP: -4.14 at 20℃
Boiling point: 564.8°F
Molecular weight: 154.17
Freezing point/melting point: 89.6°F
Vapor pressure: 5.35x10(-2)
Flash point: 300.2°F
Vapor density: 1.19
Specific gravity: 5.3
Melting Point: 32-34 °C(lit.)
Boiling Point: 283.4±0.0 °C at 760 mmHg
Flash Point: 143.9±16.5 °C
Molecular Formula: C8H10O3
Molecular Weight: 154.163
Density: 1.2±0.1 g/cm3



FIRST AID MEASURES of HEXAHYDROPHTALIC ANHYDRIDE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXAHYDROPHTALIC ANHYDRIDE:
-Environmental precautions
Do not let product enter drains.
-Methods and materials for containment and cleaning up
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXAHYDROPHTALIC ANHYDRIDE:
-Extinguishing media
*Suitable extinguishing media
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
-Further information
Prevent fire extinguishing water from contaminating surface water or the ground water
system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXAHYDROPHTALIC ANHYDRIDE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
required
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure
Do not let product enter drains.



HANDLING and STORAGE of HEXAHYDROPHTALIC ANHYDRIDE:
-Precautions for safe handling
*Advice on safe handling
Work under hood.
Do not inhale substance/mixture.
*Hygiene measures
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities
*Storage conditions
Tightly closed.
Dry.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of HEXAHYDROPHTALIC ANHYDRIDE:
-Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions
No data available
-Conditions to avoid
no information available



SYNONYMS:
Hexahydrophthalic anhydride
85-42-7
Hexahydroisobenzofuran-1,3-dione
HHPA
1,2-Cyclohexanedicarboxylic anhydride
1,3-Isobenzofurandione, hexahydro-
Lekutherm Hardener H
Hexahydrophthalic acid anhydride
Araldite HT 907
Cyclohexane-1,2-dicarboxylic anhydride
1,2-Cyclohexanedicarboxylic acid anhydride
octahydro-2-benzofuran-1,3-dione
NT 907
Hexahydro-2-benzofuran-1,3-dione
NSC 8622
3a,4,5,6,7,7a-hexahydro-2-benzofuran-1,3-dione
hexahydro-1,3-isobenzofurandione
CHEBI:103210
EINECS 201-604-9
Cyclohexane-1,2-dicarboxylic acid anhydride
DTXSID8026515
HSDB 7912
EINECS 238-009-9
(+)-trans-1,2-Cyclohexanedicarboxylic Anhydride
MFCD00064863
1,2-Cyclohexane dicarboxylic anhydride
EC 201-604-9
1,2-Cyclohexanedicarboxylic anhydride, cis + trans
Hexahydrophthalic anhydride(HHPA)
Hexahydroisobenzofuran-1,3-dione
trans-1,2-Cyclohexanedicarboxylic anhydride
1,3-Isobenzofurandione, hexahydro-, trans-
trans-Cyclohexane-1,2-dicarboxylic anhydride
NSC-8622
MFCD00674195
(3aR,7AS)-hexahydroisobenzofuran-1,3-dione
rel-(3aR,7aR)-Hexahydroisobenzofuran-1,3-dione
hexahydrophtalic anhydride
Epitope ID:122664
SCHEMBL15324
3a,4,5,6,7,7a-hexahydroisobenzofuran-1,3-dione
CHEMBL273968
DTXCID906515
NSC8622
Tox21_200661
BBL011768
STK387488
Hexahydro-2-benzofuran-1,3-dione #
2,4,5,6-tetrahydrophthalic anhydride
AKOS000119684
AKOS016352936
CS-W018047
DS-4586
SB44842
CAS-85-42-7
NCGC00248785-01
NCGC00258215-01
AC-19638
SY234482
LS-183520
C1417
C1657
FT-0623877
FT-0627011
FT-0637021
FT-0657907
FT-0659322
EN300-18014
D70901
A841328
A855212
J-501171
J-521450
Q26840977
Z57127491
F0001-0429
1,2-Cyclohexanedicarboxylic acid anhydride predominately cis
InChI=1/C8H10O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h5-6H,1-4H
HHPA
cyclohexane-1,2-dicarboxylic anhydride
1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE
Hexahydro-isobenzofuran-1,3-dione
1,3-Isobenzofurandione, hexahydro-
Hexahydrophthalic Anhydride (HHPA)
NT 907
C6H10(CO)2O
Araldite HT 907
RRSYY(Selfotel)-1
Cyclohexane-1,2-dicarboxylic anhydride
1,2-cyclohexanedicarboxylic anhydride
hexahydrophthalic anhydride
HHPSA
HH-PSA
HHPA
hexahydroisobenzofuran-1,3-dione
HHPA
1,2-cyclohexanedicarboxylic anhydride
1,2-Cyclohexanedicarboxylic acid anhydride,
cyclohexane-1,2-dicaboxylic anhydride,
cis and trans mixture
HHPA
HHPAA
hexahydrophthalic acid anhydride,
hexahydro-1,3-isobenzofurandione
Hexahydrophthalic anhydride
Hexahydroisobenzofuran-1,3-dione
1,2-Cyclohexanedicarboxylic anhydride
HHPA
Hexahydrophthalic anhydride
1,2-Cyclohexanedicarboxylic Anhydride
MFCD00064863
EINECS 201-604-9
1,2-CYCLOHEXANE DICARBOXYLIC ANHYDRIDE
Hexahydrophthalic anhydride
Hexahydro-2-benzofuran-1,3-dione
1,3-Isobenzofurandione, hexahydro-
85-42-7
1,3-Isobenzofurandione, hexahydro-
1,2-CYCLOHEXANDICARBONSAEUREANHYDRID
1,2-Cyclohexanedicarboxylic acid anhydride
1,2-Cyclohexanedicarboxylic anhydride
anhidrido ciclohexano-1,2-dicarboxilico
Anhydride cyclohexane-1,2-dicarboxylique
Araldite Hardener HY 925
Araldite HT 904
Araldite HT 907
Araldite HY 907
Araldite HY 925
Cyclohexan-1,2-dicarbonsaureanhydrid
cyclohexane-1,2-dicarboxylic anhydride
Cyclohexanedicarboxylic anhydride
Epilox H 11-01
Hexahydro-1,3-isobenzofurandione
Hexahydrophthalic acid anhydride
Lekutherm Hardener H
NSC 8622
PHTHALIC ANHYDRIDE, HEXAHYDRO-
Rikacid HH
Rikacid HH-A
Rikacid HHPA
Rikacid MH 700E
Rutadur AG
Rutapox HX
EINECS 201-604-9
1,2-Cyclohexane dicarboxylic anhydride
Cyclohexane-1,2-dicarboxylic acid anhydride
Cyclohexane-1,2-dicarboxylic anhydride
HHPA
102483-85-2
109265-67-0
117276-22-9
95327-28-9

HEXAHYDROPHTHALIC ANHYDRIDE
hexahydrophthalic anhydride Cyclohexane-1,2-dicarboxylic acid anhydride , also called hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) , is a chemical compound from the group of cyclic carboxylic acid anhydrides . There are two carboxylic acid groups in the ortho position on a cyclohexane ring , which together form an anhydride . Extraction and representation Cyclohexane-1,2-dicarboxylic acid anhydride is produced by the nuclear hydrogenation of phthalic anhydride . [4] This additional process step is one reason for the higher price compared to the aromatic phthalic anhydride. Manufacture of HH-PSA Usage Cyclohexane-1,2-dicarboxylic acid anhydride is used as a monomer in various areas of polymer chemistry . So is z. B. to mention the application as an alternative to phthalic anhydride(Hekzahidroftalik anhidrit ) . What is desired here is better weather resistance, especially against UV light , with high hardness at the same time, which can be achieved by using hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ). [5] Furthermore, with the help of cyclohexane-1,2-dicarboxylic acid anhydride, binders, polyester resins , for paint applications with a significantly lower viscosity compared to those based on isophthalic acidbe generated. This results in a higher processing solids content which is of great interest in times when a lot of attention is paid to environmental protection . [5] Processing solids are understood to be the non-volatile content of a paint system. Since the volatile components are mostly organic solvents ( VOC ), their share should be kept as low as possible. In addition to reducing the absolute amount of paint required or switching to aqueous systems, increasing the processing solids is the best option here. In addition to being used as a binder in paints, cyclohexane-1,2-dicarboxylic acid anhydride can also be used as an anhydride hardener for epoxy resins . One application would be casting resin compounds which can cure at room temperature or at elevated temperatures. The higher price compared to phthalic anhydride should also be noted here. [6] Structural formula Structural formula of hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) Structural formula of hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) General Surname Cyclohexane-1,2-dicarboxylic anhydride other names HH-PSA 1,2-cyclohexanedicarboxylic anhydride Hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) Molecular formula C 8 H 10 O 3 Brief description vitreous, colorless and odorless mass [1] External identifiers / databases CAS number 85-42-7 H and P phrases H: 317-318-334 P: 261-280-284-304 + 340-305 + 351 + 338 + 310 [1] Authorization procedure under REACH of particular concern : serious effects on human health are considered likely Hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) Chemical Properties,Uses,Production Description Hexahydrophthalic anhydride (HHPA(Hekzahidroftalik anhidrit )) is widely used for electronics applications, e.g. HHPA(Hekzahidroftalik anhidrit ) cured epoxy resins have excellent dielectric properties, high-temperature stability, and high glass transition temperatures. HHPA(Hekzahidroftalik anhidrit , Hexahydrophthalic anhydride) is used as a curing agent in adhesive coatings and sealant materials, e.g. for the second-generation two-part epoxy adhesive synthesis. Hexahydrophthalic anhydride is also used in the manufacture of alkyd and polyester resins, insecticides, and rust preventives. References [1] Guy Rabilloud, High Performance Polymers. Vol. 1 Conductive Adhesives, 1997 [2] John Burke Sullivan and Gary R. Krieger, Clinical Environmental Health and Toxic Exposures, 2001 [3] B. A. G. Jönsson, H. Welinder, C. Hansson and B. Ståhlbom, Occupational exposure to hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) : air analysis, percutaneous absorption, and biological monitoring, International Archives of Occupational and Environmental Health 1993, vol. 65, 43-47 Chemical Properties White crystalline powder Uses Intermediate for alkyds, plasticizers, insect repellents, and rust inhibitors; hardener in epoxy resins. Definition ChEBI: A cyclic dicarboxylic anhydride that is the cyclic anhydride of hexahydrophthalic anhydride acid. (Hekzahidroftalik anhidrit ) Hazard Toxic by inhalation, strong irritant to eyes and skin. Purification Methods It has been obtained by heating the trans-acid or anhydride at 200o. Crystallise it from *C6H6/Et2O or distil it. [Kohler & Jansen J Am Chem Soc 60 2145 1938, Abell J Org Chem 22 769 1957, Beilstein 17 II 452, 17 III/IV 5931.] Hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) Preparation Products And Raw materials Raw materials Tetrachlorophthalic anhydride Preparation Products Hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) Suppliers HHPA!is!a!solid!anhydride!hardener!for!epoxy!resins,!manufactured!by!Polynt!SpA.!Due!to!its! high!resistance!to!discoloration,!HHPA!is!preferred!over!other!alicyclic!anhydrides!in!casting!and! coating!applications.!In!addition, HHPA’s!low!melt!viscosity,!as!well!as!its!high!mix!ratio!with! epoxy,!makes!it!particularly!suitable!for!applications!where!high!filler!loadings!are!required.!! HHPA!is!also!used!as!an!intermediate!for!alkyds,!plasticizers,!insect!repellents!and!rust! inhibitors. Chemical!Name:!!!!!!!!! Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) !!! Molecular!Formula: C8H10O3 Molecular!Weight:!!! 154.17 CAS!Number:!!!!!!!!!!!!!!85R42R7 Typical$Applications$for$HHPA$Cured$Epoxy$Resins • Durable,!high!gloss,!weather!resistant!coatings!! • Potting!compounds! • Pressure!gelation!moldings!for!outdoor!electrical!applications HexaHydroPhthalic Anhydride is a white solid or clear liquid if melted with molecular formula C8H10O3. Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) HexaHydroPhthalic Anhydride Chemical Structure Composition. Uses HHPA Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) is mainly used as an intermediate for coating resins (alkyds, polyesters), plasticizers, sealant, curing agent in adhesive, insect repellents, rust inhibitors, electronics applications. HHPA’s Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) low melt viscosity, as well as its high mix ratio with epoxy resins, makes it particularly suitable as hardener for epoxy resin for applications where high filler loadings are required. HHPA Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) is preferred over other aromatic anhydrides in casting and coating applications for his higher resistance to yellowing. HHPA Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) has high-temperature stability, excellent dielectric properties, and high glass transition temperatures. Description: Hexahydrophthalic Anhydride (HHPA, Hekzahidroftalik anhidrit) is a saturated dicarboxylic anhydride and will undergo most of the reactions typical of this class of compounds. It is supplied as a white low-melting solid (38°C) which is miscible with most organic solvents. In water, it hydrolyzes to hexahydrophthalic anhydride acid Hekzahidroftalik anhidrit. Application Information: Milldride HHPA Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) is a very effective curing agent for epoxy resins. It is also used in the preparation of alkyd and polyester resins where good color stability is important. HHPA Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) cured epoxies are characterized by reduced color and improved electrical and physical properties as compared to amine-cured products. The low melting point of HHPA allows it to be easily handled and blended with liquid resins. Viscosities of the HHPA-epoxy Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) mixtures are lower, pot life is extended in the absence of catalyst and curing reaction is less exothermic than with other hardeners. Areas of application including casting, laminating, embedding, coating, and impregnating electrical components. Chemical Formula: C8H10O3 Post-shift and next-morning urine was sampled from workers exposed to hexahydrophtalic anhydride (HHPA) Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) , an epoxy hardener, sensitising at low exposure levels. Exposure levels of HHPA Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) in air (gas chromatography, GC) in the range of 30-270 micrograms/m3 corresponded to urinary concentrations of 0.9-2.8 mumol hexahydrophthalic anhydride acid (HHP acid Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) ; GC-mass spectrometry)/mmol creatinine. In the morning samples the concentrations were less than 0.04-0.3 mumol HHP Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) acid/mmol creatinine. In unexposed controls, the level was less than 0.1 mumol/mmol creatinine. A correlation was found between the time-weighted levels of HHPA Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) in air and HHP acid in the post-shift urine (rs = 0.93; P less than 0.023), indicating that the determination of HHP acid Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) in urine is suitable for biologic monitoring of HHPA Hexahydrophthalic Anhydride(Hekzahidroftalik anhidrit ) exposure. Methyl hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) is produced from methyl tetrahydrophthalic anhydride by catalytic hydrogenation. It is a high-performance product among acid anhydride-type solidifying agent, not only has the typical performances as methyl tetrahydrophthalic anhydride: high purity, light color liquid, low viscosity, low volatility, low toxicity, low heating loss, stable performances, long use life, low freezing point, and can be stored for a long time under room temperature; but also has more excellent performances than that of methyl tetrahydrophthalic anhydride: colorless, transparent, basically unchange color after being added accelerant and epoxyl solidified substance appears white; good resistance to heat, especially under the temperature lower than 150°C, epoxyl solidified substance are of excellent mechanical and electric properties, excellent weatherability, not be affected by light and heat, good moisture resistance, high reaction activity, fast solidifying speed and short gelation time. Uses: 1.as solidifying agent for epoxy resins: MHHPA hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) is heating-solidification type acid anhydride solidifying agent, mainly used in electrical and electronic field, with low melting point, the compounding matter with alicyclic epoxy resin is of low viscosity, long use life, excellent heat resistance and high-temperature electric properties, can be used in dipping of coil of electric apparatus, casting of electric parts and sealing of semiconductor. 2.as adhesive: the alicyclic epoxy adhesive made from MHHPA hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) has similar refractive index as optical glass, low internal stress after solidifying, high adhesion strength, color unchangeable, resistance to aging, applicable for cohering large-area optical parts. 3.as insecticide, plasticizer and antirust, etc. method for manufacturing hexahydrophthalic anhydride diglycidyl ester is provided to improve outdoor weather resistance with maintaining heat resistance, transparency and electrical insulation. A method for manufacturing hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) diglycidyl ester comprises the steps of mixing hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) with epichlorohydrin in the presence of a solvent to produce hexahydrodicarboxylic acid by hydrolysis; mixing hexahydrodicarboxylic acid (Hekzahidroftalik anhidrit ) , epichlorohydrin and a catalyst to produce chlorohydrin ester capable of dechlorination; and putting the chlorohydrin ester to an alkali metal compound to produce hexahydrophthalic anhydride diglycidyl ester (See the reaction scheme). Cyclohexane-1,2-dicarboxylic acid anhydride , also called hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) , is a chemical compound from the group of cyclic carboxylic acid anhydrides . There are two carboxylic acid groups in the ortho position on a cyclohexane ring , which together form an anhydride . Extraction and representation Cyclohexane-1,2-dicarboxylic acid anhydride is produced by the nuclear hydrogenation of phthalic anhydride . [4] This additional process step is one reason for the higher price compared to the aromatic phthalic anhydride. Manufacture of HH-PSA Usage Cyclohexane-1,2-dicarboxylic acid anhydride is used as a monomer in various areas of polymer chemistry . So is z. B. to mention the application as an alternative to phthalic anhydride . What is desired here is better weather resistance, especially against UV light , with high hardness at the same time, which can be achieved by using hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) . [5] Furthermore, with the help of cyclohexane-1,2-dicarboxylic acid anhydride, binders, polyester resins , for paint applications with a significantly lower viscosity compared to those based on isophthalic acidbe generated. This results in a higher processing solids content which is of great interest in times when a lot of attention is paid to environmental protection . [5] Processing solids are understood to be the non-volatile content of a paint system. Since the volatile components are mostly organic solvents ( VOC ), their share should be kept as low as possible. In addition to reducing the absolute amount of paint required or switching to aqueous systems, increasing the processing solids is the best option here. In addition to being used as a binder in paints, cyclohexane-1,2-dicarboxylic acid anhydride can also be used as an anhydride hardener for epoxy resins . One application would be casting resin compounds which can cure at room temperature or at elevated temperatures. The higher price compared to phthalic anhydride should also be noted here. [6] Structural formula Structural formula of hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) Structural formula of hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) General Surname Cyclohexane-1,2-dicarboxylic anhydride other names HH-PSA 1,2-cyclohexanedicarboxylic anhydride Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) Molecular formula C 8 H 10 O 3 Brief description vitreous, colorless and odorless mass [1] H and P phrases H: 317-318-334 P: 261-280-284-304 + 340-305 + 351 + 338 + 310 [1] Authorization procedure under REACH of particular concern : serious effects on human health are considered likely Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) Chemical Properties,Uses,Production Description Hexahydrophthalic anhydride (HHPA, (Hekzahidroftalik anhidrit ) ) is widely used for electronics applications, e.g. HHPA (Hekzahidroftalik anhidrit, Hexahydrophthalic anhydride ) cured epoxy resins have excellent dielectric properties, high-temperature stability, and high glass transition temperatures. HHPA (Hekzahidroftalik anhidrit, Hexahydrophthalic anhydride ) is used as a curing agent in adhesive coatings and sealant materials, e.g. for the second-generation two-part epoxy adhesive synthesis. Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit) is also used in the manufacture of alkyd and polyester resins, insecticides, and rust preventives. References [1] Guy Rabilloud, High Performance Polymers. Vol. 1 Conductive Adhesives, 1997 [2] John Burke Sullivan and Gary R. Krieger, Clinical Environmental Health and Toxic Exposures, 2001 [3] B. A. G. Jönsson, H. Welinder, C. Hansson and B. Ståhlbom, Occupational exposure to hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) : air analysis, percutaneous absorption, and biological monitoring, International Archives of Occupational and Environmental Health 1993, vol. 65, 43-47 Chemical Properties White crystalline powder Uses Intermediate for alkyds, plasticizers, insect repellents, and rust inhibitors; hardener in epoxy resins. Definition ChEBI: A cyclic dicarboxylic anhydride that is the cyclic anhydride of hexahydrophthalic anhydride acid. (Hekzahidroftalik anhidrit ) Hazard Toxic by inhalation, strong irritant to eyes and skin. Purification Methods It has been obtained by heating the trans-acid or anhydride at 200o. Crystallise it from *C6H6/Et2O or distil it. [Kohler & Jansen J Am Chem Soc 60 2145 1938, Abell J Org Chem 22 769 1957, Beilstein 17 II 452, 17 III/IV 5931.] Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) Preparation Products And Raw materials Raw materials Tetrachlorophthalic anhydride Preparation Products Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) Suppliers HHPA!is!a!solid!anhydride!hardener!for!epoxy!resins,!manufactured!by!Polynt!SpA.!Due!to!its! high!resistance!to!discoloration,!HHPA!is!preferred!over!other!alicyclic!anhydrides!in!casting!and! coating!applications.!In!addition, HHPA’s!low!melt!viscosity,!as!well!as!its!high!mix!ratio!with! epoxy,!makes!it!particularly!suitable!for!applications!where!high!filler!loadings!are!required.!! HHPA!is!also!used!as!an!intermediate!for!alkyds,!plasticizers,!insect!repellents!and!rust! inhibitors. Chemical!Name:!!!!!!!!! Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) !!! Molecular!Formula: C8H10O3 Molecular!Weight:!!! 154.17 CAS!Number:!!!!!!!!!!!!!!85R42R7 Typical$Applications$for$HHPA$Cured$Epoxy$Resins • Durable,!high!gloss,!weather!resistant!coatings!! • Potting!compounds! • Pressure!gelation!moldings!for!outdoor!electrical!applications HexaHydroPhthalic Anhydride (Hekzahidroftalik anhidrit ) is a white solid or clear liquid if melted with molecular formula C8H10O3. Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) HexaHydroPhthalic Anhydride (Hekzahidroftalik anhidrit ) Chemical Structure Composition. Uses HHPA Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) is mainly used as an intermediate for coating resins (alkyds, polyesters), plasticizers, sealant, curing agent in adhesive, insect repellents, rust inhibitors, electronics applications. HHPA’s Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) low melt viscosity, as well as its high mix ratio with epoxy resins, makes it particularly suitable as hardener for epoxy resin for applications where high filler loadings are required. HHPA Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) is preferred over other aromatic anhydrides in casting and coating applications for his higher resistance to yellowing. HHPA Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) has high-temperature stability, excellent dielectric properties, and high glass transition temperatures. Description: Hexahydrophthalic Anhydride (HHPA, (Hekzahidroftalik anhidrit ) ) is a saturated dicarboxylic anhydride and will undergo most of the reactions typical of this class of compounds. It is supplied as a white low-melting solid (38°C) which is miscible with most organic solvents. In water, it hydrolyzes to hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) acid. Application Information: Milldride HHPA Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) is a very effective curing agent for epoxy resins. It is also used in the preparation of alkyd and polyester resins where good color stability is important. HHPA Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) cured epoxies are characterized by reduced color and improved electrical and physical properties as compared to amine-cured products. The low melting point of HHPA Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) allows it to be easily handled and blended with liquid resins. Viscosities of the HHPA-epoxy Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) mixtures are lower, pot life is extended in the absence of catalyst and curing reaction is less exothermic than with other hardeners. Areas of application including casting, laminating, embedding, coating, and impregnating electrical components. Chemical Formula: C8H10O3 Post-shift and next-morning urine was sampled from workers exposed to hexahydrophtalic anhydride (HHPA, (Hekzahidroftalik anhidrit ) ), an epoxy hardener, sensitising at low exposure levels. Exposure levels of HHPA in air (gas chromatography, GC) in the range of 30-270 micrograms/m3 corresponded to urinary concentrations of 0.9-2.8 mumol hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) acid (HHP Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) acid; GC-mass spectrometry)/mmol creatinine. In the morning samples the concentrations were less than 0.04-0.3 mumol HHP Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) acid/mmol creatinine. In unexposed controls, the level was less than 0.1 mumol/mmol creatinine. A correlation was found between the time-weighted levels of HHPA Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) in air and HHP Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) acid in the post-shift urine (rs = 0.93; P less than 0.023), indicating that the determination of HHP acid in urine is suitable for biologic monitoring of HHPA Hexahydrophthalic Anhydride (Hekzahidroftalik anhidrit ) exposure. Methyl hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) is produced from methyl tetrahydrophthalic anhydride by catalytic hydrogenation. It is a high-performance product among acid anhydride-type solidifying agent, not only has the typical performances as methyl tetrahydrophthalic anhydride: high purity, light color liquid, low viscosity, low volatility, low toxicity, low heating loss, stable performances, long use life, low freezing point, and can be stored for a long time under room temperature; but also has more excellent performances than that of methyl tetrahydrophthalic anhydride: colorless, transparent, basically unchange color after being added accelerant and epoxyl solidified substance appears white; good resistance to heat, especially under the temperature lower than 150°C, epoxyl solidified substance are of excellent mechanical and electric properties, excellent weatherability, not be affected by light and heat, good moisture resistance, high reaction activity, fast solidifying speed and short gelation time. Uses: 1.as solidifying agent for epoxy resins: MHHPA hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) is heating-solidification type acid anhydride solidifying agent, mainly used in electrical and electronic field, with low melting point, the compounding matter with alicyclic epoxy resin is of low viscosity, long use life, excellent heat resistance and high-temperature electric properties, can be used in dipping of coil of electric apparatus, casting of electric parts and sealing of semiconductor. 2.as adhesive: the alicyclic epoxy adhesive made from MHHPA hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) has similar refractive index as optical glass, low internal stress after solidifying, high adhesion strength, color unchangeable, resistance to aging, applicable for cohering large-area optical parts. 3.as insecticide, plasticizer and antirust, etc. method for manufacturing hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) diglycidyl ester is provided to improve outdoor weather resistance with maintaining heat resistance, transparency and electrical insulation. A method for manufacturing hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) diglycidyl ester comprises the steps of mixing hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) with epichlorohydrin in the presence of a solvent to produce hexahydrodicarboxylic acid by hydrolysis; mixing hexahydrodicarboxylic acid, epichlorohydrin and a catalyst to produce chlorohydrin ester capable of dechlorination; and putting the chlorohydrin ester to an alkali metal compound to produce hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) diglycidyl ester (See the reaction scheme). 13 2012/10/18 Member State Norway The Norwegian CA supports that hexahydrophthalic anhydride (HHPA, (Hekzahidroftalik anhidrit ) )fulfill the criteria of article 57 f) since evidence exists of serious effects to humans which give rise to equivalent level of concern as CMR substances. HHPA hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) is harmonized classified as a strong respiratory sensitizer (Resp. Sens. 1) in the CLP regulation and no "safe" no effect level can be derived as regards to the induction of sensitization. During the elicitation phase, the substance may evoke chronic inflammation of the lungs and this can lead to serious and permanent impairment of the lungs. The induced sensitization is irreversible, and exposure of the substance may result in a considerable increased risk of elicitation of respiratory sensitization of affected persons. This may cause limitations of normal working life and could require long term medication. We support that the criteria of article 57 f) is fulfilled and that this substance is of equivalent level of concern as CMR (Cat. 1 or 2) substances. HHPA should be identified as a SVHC substance. Member State Sweden We agree with the argumentation put forward in the Annex XV dossier and therefore consider hexahydrophthalic anhydride – HHPA hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) to be a SVHC substance of equivalent level of concern according to Article 57(f). The substance is a classified respiratory sensitizer which may cause severe and irreversible health effects, which clearly affect the quality of life of affected individuals and also high costs for society. It is difficult to establish safe exposure levels for respiratory sensitizers like HHPA hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) , which is another reason for concern. Further, it is noted that this severe endpoint has not been taken into account by registrants in their chemical safety assessment in the Registration dossier. 1. Introduction of Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ), with the CAS registry number 85-42-7, is also known as 1,2-Cyclohexanedicarboxylic acid anhydride, 1,3-Isobenzofurandione, hexahydro-. It belongs to the product categories of Diels-Alder Adducts; Organics. What's more, its systematic name is Hexahydro-2-benzofuran-1,3-dione. Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) can be used as coatings, epoxy curing agent, polyester resin, adhesive, plasticizer, intermediate of plasticizers and insect repellents. This chemical should be sealed and stored in a cool, ventilated and dry place. Moreover, it should be protected from moisture, sunburn and fire. 2. Properties of Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) (1)ACD/LogP: 0.762; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.76; (4)ACD/LogD (pH 7.4): 0.76; (5)ACD/BCF (pH 5.5): 2.24; (6)ACD/BCF (pH 7.4): 2.24; (7)ACD/KOC (pH 5.5): 61.91; (8)ACD/KOC (pH 7.4): 61.91; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 43.37 Å2; (13)Index of Refraction: 1.502; (14)Molar Refractivity: 36.813 cm3; (15)Molar Volume: 124.728 cm3; (16)Polarizability: 14.594×10-24cm3; (17)Surface Tension: 42.23 dyne/cm; (18)Density: 1.236 g/cm3; (19)Flash Point: 143.909 °C; (20)Enthalpy of Vaporization: 52.227 kJ/mol; (21)Boiling Point: 283.351 °C at 760 mmHg; (22)Vapour Pressure: 0.003 mmHg at 25°C. 3. Structure Descriptors of Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) (1)SMILES: O=C1OC(=O)C2C1CCCC2 (2)Std. InChI: InChI=1S/C8H10O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h5-6H,1-4H2 (3)Std. InChIKey: MUTGBJKUEZFXGO-UHFFFAOYSA-N 4. Safety Information of Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) Hazard Symbols:HarmfulXn Risk Codes: R41:Risk of serious damage to the eyes. R42/43:May cause sensitization by inhalation and skin contact. Safety Description: S23:Do not breathe vapour. S24:Avoid contact with skin. S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39:Wear suitable gloves and eye/face protection. 5. Preparation of Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) can be prepared by cyclohex-1-ene-1,2-dicarboxylic acid anhydride at the temperature of 95 °C. This reaction will need reagent H2 and solvent dimethylformamide with the reaction time of 3 hours. This reaction will also need catalyst Raney-Ni. The yield is about 88%. 1,3-Isobenzofurandione, hexahydro- can be prepared by cyclohex-1-ene-1,2-dicarboxylic acid anhydride at the temperature of 95 °C 6. Uses of Hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) can be used to produce 2-trichloroacetyl-1-cyclohexanecarboxylic acid at the temperature of 60 °C. It will need reagent dibenzo-18-crown-6 and solvent acetonitrile with the reaction time of 6 hours. The yield is about 81%. 1,3-Isobenzofurandione, hexahydro- can be used to produce 2-trichloroacetyl-1-cyclohexanecarboxylic acid at the temperature of 60 °C 7. Other details of Hexahydrophthalic anhydride(Hekzahidroftalik anhidrit ) When you are using this chemical, please be cautious about it as the following: Hexahydrophthalic anhydride (Hekzahidroftalik anhidrit ) has a risk of serious damage to eyes and it may cause sensitisation by inhalation and skin contact. You should not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer). When using it, you must avoid contact with skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective gloves and eye/face protection.
HEXAHYDROPHTHALIC ANHYDRIDE (HHPA)
Hexahydrophthalic anhydride (HHPA) is widely used for electronics applications, e.g. HHPA cured epoxy resins have excellent dielectric properties, high-temperature stability, and high glass transition temperatures.
Hexahydrophthalic anhydride (HHPA) is used as a curing agent in adhesive coatings and sealant materials, e.g. for the second-generation two-part epoxy adhesive synthesis.
Hexahydrophthalic anhydride (HHPA) is also used in the manufacture of alkyd and polyester resins, insecticides, and rust preventives.

CAS: 85-42-7
MF: C8H10O3
MW: 154.16
EINECS: 201-604-9

Synonyms
1,2-Cyclohexanedicarboxylic Acid anhydride;1,3-Isobenzofurandione, hexahydro-;3-Isobenzofurandione,hexahydro-1;Araldite HT 907;hexahydro-3-isobenzofurandione;Lekutherm Hardener H;NT 907;CALCIUM 2-NAPTHYLPHOSPHATE;Hexahydrophthalic anhydride;85-42-7;Hexahydroisobenzofuran-1,3-dione;1,2-Cyclohexanedicarboxylic anhydride;HHPA;1,3-Isobenzofurandione, hexahydro-;Lekutherm Hardener H;Hexahydrophthalic acid anhydride;Araldite HT 907;Cyclohexane-1,2-dicarboxylic anhydride;1,2-Cyclohexanedicarboxylic acid anhydride;octahydro-2-benzofuran-1,3-dione;NT 907;hexahydro-1,3-isobenzofurandione;Hexahydro-2-benzofuran-1,3-dione;NSC 8622;71749-03-6;3a,4,5,6,7,7a-hexahydro-2-benzofuran-1,3-dione;CHEBI:103210;(+)-trans-1,2-Cyclohexanedicarboxylic Anhydride;Cyclohexane-1,2-dicarboxylic acid anhydride;DTXSID8026515;MFCD00064863;1,2-Cyclohexane dicarboxylic anhydride
;1,2-Cyclohexanedicarboxylic anhydride, cis + trans;Hexahydrophthalic anhydride(HHPA);Hexahydroisobenzofuran-1,3-dione;trans-1,2-Cyclohexanedicarboxylic anhydride
;1,3-Isobenzofurandione, hexahydro-, trans-;trans-Cyclohexane-1,2-dicarboxylic anhydride
;EINECS 201-604-9;NSC-8622;MFCD00674194;MFCD00674195;HSDB 7912;EINECS 238-009-9;(3aR,7AS)-hexahydroisobenzofuran-1,3-dione;rel-(3aR,7aR)-Hexahydroisobenzofuran-1,3-dione;hexahydrophtalic anhydride;Epitope ID:122664;EC 201-604-9;SCHEMBL15324;3a,4,5,6,7,7a-hexahydroisobenzofuran-1,3-dione;CHEMBL273968;DTXCID906515;NSC8622;Tox21_200661;Hexahydro-2-benzofuran-1,3-dione #;2,4,5,6-tetrahydrophthalic anhydride;AKOS000119684;AKOS016352936;CS-W018047;DS-4586;SB44842;CAS-85-42-7;NCGC00248785-01;NCGC00258215-01;AC-19638;SY234481;SY234482;C1417;C1657;NS00005320;EN300-18014;D70901;A841328;A855212
;J-501171;J-521450;Q26840977;Z57127491;F0001-0429;1,2-Cyclohexanedicarboxylic acid anhydride predominately cis;InChI=1/C8H10O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h5-6H,1-4H

A cyclic dicarboxylic anhydride that is the cyclic anhydride of hexahydrophthalic acid.
Predominantly cis Hexahydrophthalic anhydride (HHPA) is a cyclic anhydride that can be used for a variety of applications such as: plasticizer, rust inhibitor, and a curing agent for epoxy based resins.
Hexahydrophthalic anhydride (HHPA) is mainly used as intermediate for coating resins, plasticizers, insect repellents and rust inhibitors, and as hardener for epoxy resins.
Hexahydrophthalic anhydride (HHPA) is preferred over other cyclic anhydrides in casting and coating applications for his higher resistance to yellowing.
Hexahydrophthalic anhydride (HHPA) is a cyclic dicarboxylic anhydride that is the cyclic anhydride of hexahydrophthalic acid.
Hexahydrophthalic anhydride (HHPA) has a role as an allergen.
Hexahydrophthalic anhydride (HHPA) is a cyclic dicarboxylic anhydride and a tetrahydrofurandione.

Hexahydrophthalic anhydride (HHPA) Chemical Properties
Melting point: 32-34 °C(lit.)
Boiling point: 158 °C17 mm Hg(lit.)
Density: 1.18
Vapor pressure: 0.31Pa at 25℃
Refractive index: 1.4620 (estimate)
RTECS: NP6895168
Fp: >230 °F
Storage temp.: Store below +30°C.
Solubility: Chloroform, Methanol (Slightly)
Form: Solid
pka: 4.14[at 20 ℃]
Color: White to Off-White
Water Solubility: 4.2g/L at 20℃
Sensitive: Moisture Sensitive
BRN: 83213
Exposure limits ACGIH: Ceiling 0.005 mg/m3
Stability: Moisture Sensitive
LogP: -4.14 at 20℃
CAS DataBase Reference: 85-42-7(CAS DataBase Reference)
NIST Chemistry Reference: Hexahydrophthalic anhydride (HHPA)(85-42-7)
EPA Substance Registry System: Hexahydrophthalic anhydride (HHPA) (85-42-7)

Uses
Intermediate for alkyds, plasticizers, insect repellents, and rust inhibitors; hardener in epoxy resins.
Hexahydrophthalic anhydride (HHPA), in combination with triethaylamine (TEA), can be used as a polymerization initiator in the preparation of polyester based resins.
Hexahydrophthalic anhydride (HHPA) can also be used as a hardener to cure 1,4-butanediol diglycidyl ether which can be used as an epoxy based system for electronic devices.
Predominantly Hexahydrophthalic anhydride (HHPA) is a cyclic anhydride that can be used for a variety of applications such as: plasticizer, rust inhibitor, and a curing agent for epoxy based resins.

Hexahydrophthalic anhydride (HHPA), in combination with triethaylamine (TEA), can be used as a polymerization initiator in the preparation of polyester based resins.
Hexahydrophthalic anhydride (HHPA) can also be used as a hardener to cure 1,4-butanediol diglycidyl ether which can be used as an epoxy based system for electronic devices.
Hexahydrophthalic anhydride (HHPA) can be used to produce 2-trichloroacetyl-1-cyclohexanecarboxylic acid at the temperature of 60 °C.
Hexahydrophthalic anhydride (HHPA) will need reagent dibenzo-18-crown-6 and solvent acetonitrile with the reaction time of 6 hours.
The yield is about 81%.

Synthesis
Hexahydrophthalic anhydride (HHPA) is obtained by reacting ciscyclohexane-1, 2-dicarboxylic acid with oxalyl chloride.
Combine ciscyclohexane-1, 2-dicarboxylic acid (1 mmol, 172 mg) and oxalyl chloride (1.2 mmol, 152 mg, 0.103 ml) in dry toluene (5 mL) and add a drop of freshly distilled DMF.
Purge the reaction vessel with argon and heat the reaction under stirring for 3 h.
Stop the stirring, decant the toluene solution and filter. Evaporate the volatiles.
Transform into crystalline form by trituration with diethyl ether. 1H NMR (400 MHz, CDCl3) | 3.18 - 3.12 (m, 2H 2CH) 1.96 - 1.83 (m, 4H 2CH2) 1.57 - 1.49 (m, 4H 2CH2).
HRMS (ESI), calcd for C8H10NaO3 [M+Na]+ 175.0522, found 175.0527; calcd for C9H14NaO4 [M+CH3 OH+Na]+ 209.0784, found 209.0788.

Preparation of Hexahydrophthalic anhydride
Hexahydrophthalic anhydride (HHPA) can be prepared by cyclohex-1-ene-1,2-dicarboxylic acid anhydride at the temperature of 95 °C.
This reaction will need reagent H2 and solvent dimethylformamide with the reaction time of 3 hours.
This reaction will also need catalyst Raney-Ni.
The yield is about 88%.

Other details of Hexahydrophthalic anhydride (HHPA)
When you are using this chemical, please be cautious about it as the following:
Hexahydrophthalic anhydride has a risk of serious damage to eyes and it may cause sensitisation by inhalation and skin contact.
You should not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).
When using Hexahydrophthalic anhydride (HHPA), you must avoid contact with skin.
In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice.
When using Hexahydrophthalic anhydride (HHPA), you need wear suitable protective gloves and eye/face protection.
HEXAMETHYLDISILAZANE
Hexamethyldisilazane is an organosilicon compound used primarily as a reagent and a precursor in organic synthesis and organometallic chemistry.
Hexamethyldisilazane is commonly employed as an adhesion promoter for photoresists in photolithography and as an alternative to critical point drying in electron microscopy sample preparation.
Additionally, Hexamethyldisilazane is utilized in the preparation of trimethylsilyl ethers from hydroxy compounds and in gas chromatography-mass spectrometry to enhance the detectability of polar compounds.

CAS Number: 999-97-3
EC Number: 213-668-5
Molecular Formula: C6H19NSi2
Molecular Weight (g/mol): 161.395

Synonyms: Hexamethyldisilazane, 999-97-3, HMDS, Bis(trimethylsilyl)amine, 1,1,1,3,3,3-Hexamethyldisilazane, Hexamethylsilazane, Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, 1,1,1-Trimethyl-N-(trimethylsilyl)silanamine, Tri-Sil, TSL 8802, hexamethyl disilazane, Disilazane, 1,1,1,3,3,3-hexamethyl-, [dimethyl-(trimethylsilylamino)silyl]methane, NSC 93895, CCRIS 2456, SZ 6079, HSDB 7226, (TMS)2NH, EINECS 213-668-5, MFCD00008259, ((CH3)3Si)2NH, H36C68P1BH, CHEBI:85068, 1,1,3,3,3-Hexamethyldisilazane, Bis(trimethylsilyl)amidolithium, NSC-93895, Trimethyl-N-(trimethylsilyl)silanamine, OAP, Lithium hexamethyldisilazane, Lithiumbis(trimethylsilyl)amine, Hexamethyldisilazane, hexamethyldisilizane, Lithium tris(trimethylsilyl)amine, 27495-70-1, CAS-999-97-3, NSC-252161, UNII-H36C68P1BH, AI3-51467, hexamethyldisilazan, hexamethyidisilazane, hexa-methyldisilazane, hexamethyl-disilazane, bistrimethylsilylamine, hexamethyldisilylamine, Me3SiNHSiMe3, HMDZ, bis-(trimethylsilyl)amine, (Me3Si)2NH, 1,1,1,3,3,3-HEXAMETHYL-DISILAZANE, EC 213-668-5, DISILAZANE,HEXAMETHYL, HN(TMS)2, SCHEMBL7649, CHEMBL3183662, DTXSID2025395, HEXAMETHYLDISILAZANE [MI], 1,1,3,3,3-hexamethyidisilazane, HEXAMETHYLDISILAZANE [HSDB], NSC93895, STR02905, 1,1,1,3,3,3-hexamethyldisilazan, Tox21_202428, Tox21_303281, 1,1,1,3,3,3 hexamethyldisilazane, 1,1,1,3,3,3-hexamethyidisilazane, 1,1,1.3,3,3-hexamethyldisilazane, NSC252161, STL185550, Disilazane,1,1,3,3,3-hexamethyl-, 1,1,1, 3,3,3-hexamethyldisilazane, 1,1,1,3,3,3,-hexamethyldisilazane, AKOS000120987, ZINC169743012, NCGC00164366-01, NCGC00164366-02, NCGC00257230-01, NCGC00259977-01, BP-21394, FT-0602799, H0089, Hexamethyldisilazane, reagent grade, >=99%, Hexamethyldisilazane, ReagentPlus(R), 99.9%, Silanamine,1,1-trimethyl-N-(trimethylsilyl)-, WLN: 1-SI-1&1&M-SI-1&1&1, Disilazane,1,1,3,3,3-hexamethyl-, lithium salt, Q425001, J-519891, F0001-2345, Silanamine,1,1-trimethyl-N-(trimethylsilyl)-, lithium salt, Hexamethyldisilazane, for GC derivatization, >=99.0% (GC), Hexamethyldisilazane, semiconductor grade PURANAL(TM) (Honeywell 17713), Hexamethyldisilazane, produced by Wacker Chemie AG, Burghausen, Germany, >=97.0% (GC), Hexamethyldisilazane, 1,1,1,3,3,3-Hexamethyldisilazane, 1,1,1-Trimethyl-N-(trimethylsilyl)silanamin [German] [ACD/IUPAC Name], 1,1,1-Trimethyl-N-(trimethylsilyl)silanamine [ACD/IUPAC Name], 1,1,1-Triméthyl-N-(triméthylsilyl)silanamine [French] [ACD/IUPAC Name], 213-668-5 [EINECS], 999-97-3 [RN], Bis(trimethylsilyl)amine [Wiki], disilazane, hexamethyl-, H36C68P1BH, Hexamethyldisilylamine, hmds, JM9230000, MFCD00008259 [MDL number], Silanamine, 1,1,1-trimethyl-N- (trimethylsilyl)-, Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)- [ACD/Index Name], Silazane HMN, ((CH3)3Si)2NH, (TMS)2NH, [dimethyl-(trimethylsilylamino)silyl]methane, 1,1,1,3,3,3-Hexamethyl-disilazane, 136068-19-4 [RN], Bis(trimethylsilyl)amine; HMDS, dimethyl-[methyl(trimethylsilyl)amino]silicon, Disilazane, 1,1,1,3,3,3-hexamethyl-, DISILAZANE,HEXAMETHYL, EINECS 213-668-5, hexamethyl disilazane, HEXAMETHYLDISILIZANE, HEXAMETHYLSIDILIZANE, Hexamethylsilazane, HMDS; Bis(trimethylsilyl)amine, NCGC00164366-01, OAP, STR02905, Trimethyl-N-(trimethylsilyl)silanamine, Tri-Sil, UNII:H36C68P1BH, UNII-H36C68P1BH, WLN: 1-SI-1&1&M-SI-1&1&1

Hexamethyldisilazane is used to trimethylsilylate alcohols, amines, thiols.
Hexamethyldisilazane can also be used for the preparation of trimethylsilyl ethers from hydroxy compounds

Hexamethyldisilazane is used as a solvent in organic synthesis and organometallic chemistry.
Hexamethyldisilazane is often used as an adhesion promoter for photoresist in photolithography.
Further, Hexamethyldisilazane is used for the preparation of trimethylsilyl ethers from hydroxy compounds.

Hexamethyldisilazane is used as an alternative to critical point drying during sample preparation in electron microscopy.
Hexamethyldisilazane is added to analyte to get silylated diagnostic products during pyrolysis in gas chromatography- mass spectrometry.

Bis(trimethylsilyl)amine (also known as hexamethyldisilazane and HMDS) is an organosilicon compound with the molecular formula [(CH3)3Si]2NH.
The molecule is a derivative of ammonia with trimethylsilyl groups in place of two hydrogen atoms.

An electron diffraction study shows that silicon-nitrogen bond length (173.5 pm) and Si-N-Si bond angle (125.5°) to be similar to disilazane (in which methyl groups are replaced by hydrogen atoms) suggesting that steric factors are not a factor in regulating angles in this case.
This colorless liquid is a reagent and a precursor to bases that are popular in organic synthesis and organometallic chemistry.
Additionally, Hexamethyldisilazane is also increasingly used as molecular precursor in chemical vapor deposition techniques to deposit silicon carbonitride thin films or coatings.

Hexamethyldisilazane can be, at times, a good substitute for critical point drying CPD, especially for those laboratories not having available a good critical point dryer.
Because of Hexamethyldisilazane generally rapid infiltration, Hexamethyldisilazane is ideal for the preparation of insect tissue.
However, do not expect the results, in general, to be as one would get with the use of a good critical point dryer.

Remember, we "recommend" the use of Hexamethyldisilazane only when a good operating CPD unit is just not available.
Until recently, the main application for Hexamethyldisilazane has been in life science microscopy but in more recent years, interesting applications in materials science have been found.

Hexamethyldisilazane also known as HDMS, is an organosilicon compound and molecule derived from ammonia.
Hexamethyldisilazane is a colorless liquid which is popular in organometallic chemistry and organic synthesis.

Hexamethyldisilazane appears as a liquid. May be toxic by ingestion.
Hexamethyldisilazane is irritates skin and eyes.

Hexamethyldisilazane is may emit highly toxic nitrogen oxide fumes when heated to decomposition.
Hexamethyldisilazane is used to deactivate chromatography support materials and to promote adhesion of photoresists in the electronics industry.

Hexamethyldisilazane is a stable and effectivereagent for trimethylsilylation of hydrogen-labile substrates such as alcohols,amines, and carboxylic acids.
Hexamethyldisilazane is commonly used for the protection of sensitivefunctional groups during chemical synthesis.
Owing to Hexamethyldisilazane low cost, high vapor pressure, and safety, Hexamethyldisilazane is widely used as a precursor in chemical vapor deposition(CVD) reactions.

Hexamethyldisilazane can be used in place of critical point drying for the preparation of soft tissue for SEM examination, for example, of delicate insect tissues.
Hexamethyldisilazane is faster, preserves surface detail, reduces thermal and pressure stresses, and may also reduce the extraction of cellular components compared with CPD.
Hexamethyldisilazane can be used to dry specimens such as bacteria on polycarbonate filters.

Hexamethyldisilazane is a bulk organo silicon compound, being a quite useful silanizing agent.
Hexamethyldisilazane is a reagent for the preparation of trimethylsilyl derivatives.

Hexamethyldisilazane can also be used to dehydrate cells of biomaterials for scanning electron microscopy (SEM).
Moreover, Hexamethyldisilazane is an adhesion promoter for photoresist in photolithography, and is also useful in the pyrolysis-gas chromatography-mass spectrometry to enhance the detectability of compounds with polar functional groups.

Hexamethyldisilazane is a derivative of ammonia with trimethylsilyl groups in place of two hydrogen atoms.
Hexamethyldisilazane is primarily used as a precursor to many bases common in organic synthesis and organometallic chemistry.
Hexamethyldisilazane also has applications in photolithography, electron microscopy and pyrolysis-gas chromatography-mass spectrometry.

Hexamethyldisilazane is an N-silyl compound obtained from ammonia by replacement of two of the hydrogens with trimethylsilyl groups.
Hexamethyldisilazane is a derivatisation agent used in gas chromatography mass spectrometry applications.

Hexamethyldisilazane has a role as a chromatographic reagent.
Hexamethyldisilazane derives from a hydride of an ammonia.

Hexamethyl disilazane appears as a liquid.
Hexamethyldisilazane is may be toxic by ingestion.

Hexamethyldisilazane is irritates skin and eyes.
Hexamethyldisilazane is may emit highly toxic nitrogen oxide fumes when heated to decomposition.
Hexamethyldisilazane is used to make other chemicals.

Uses of Hexamethyldisilazane:
Hexamethyldisilazane mainly used as methyl silane alkylation (such as amikacin, penicillin, cephalosporins and kinds of penicillin derivatives), hydroxyl protectants of antibiotics.
Hexamethyldisilazane is used as surface treatment agent of diatomite, white carbon black, titanium and blond additives of photoresist in the semiconductor industry.

Hexamethyldisilazane is used as treatment agent of tearing strength resistance.
Hexamethyldisilazane is used as a solvent in organic synthesis and organometallic chemistry.

Hexamethyldisilazane is used as an adhesion promoter for photoresist in photolithography.
Hexamethyldisilazane is used for the preparation of trimethylsilyl ethers from hydroxy compounds.

Hexamethyldisilazane is used as an alternative to critical point drying during sample preparation in electron microscopy.
Hexamethyldisilazane is added to analyte to get silylated diagnostic products during pyrolysis in gas chromatography- mass spectrometry.

Hexamethyldisilazane is used to deactivate chromatography support materials and to promote adhesion of photoresists in the electronics industry.
Hexamethyldisilazane is used in electronic industry as an adhesion promoter for photoresists on silicon.

Hexamethyldisilazane is used as a chemical intermediate in the production of siloxane polymers.

Use as reagent:

Hexamethyldisilazane is employed as a reagent in many organic reactions:
Hexamethyldisilazane is used as a reagent in condensation reactions of heterocyclic compounds such as in the microwave synthesis of a derivative of xanthine.

The Hexamethyldisilazane mediated trimethylsilylation of alcohols, thiols, amines and amino acids as protective groups or for intermediary organosilicon compounds is found to be very efficient and replaced TMSCl reagent.
Silylation of glutamic acid with excess hexamethyldisilazane and catalytic TMSCl in either refluxing xylene or acetonitrile followed by dilution with alcohol (methanol or ethanol) yields the derived lactam pyroglutamic acid in good yield.

Hexamethyldisilazane in the presence of catalytic iodine facilitates the silylation of alcohols in excellent yields.

Hexamethyldisilazane can be used to silylate laboratory glassware and make Hexamethyldisilazane hydrophobic, or automobile glass, just as Rain-X does.
In gas chromatography, Hexamethyldisilazane can be used to silylate OH groups of organic compounds to increase volatility, this way enabling GC-analysis of chemicals that are otherwise non-volatile.

Other Uses:
In photolithography, Hexamethyldisilazane is often used as an adhesion promoter for photoresists.
Best results are obtained by applying Hexamethyldisilazane from the gas phase on heated substrates.

In electron microscopy, Hexamethyldisilazane can be used as an alternative to critical point drying during sample preparation.
In pyrolysis-gas chromatography-mass spectrometry, Hexamethyldisilazane is added to the analyte to create silylated diagnostic products during pyrolysis, in order to enhance detectability of compounds with polar functional groups.

In plasma-enhanced chemical vapor deposition (PECVD), Hexamethyldisilazane is used as a molecular precursor as a replacement to highly flammable and corrosive gasses like SiH4, CH4, NH3 as Hexamethyldisilazane can be easily handled.
Hexamethyldisilazane is used in conjunction with a plasma of various gases such as argon, helium and nitrogen to deposit SiCN thin films/coatings with excellent mechanical, optical and electronic properties.

Industry Uses:
Adhesion/cohesion promoter
Adhesives and sealant chemicals
Chemical reaction regulator
Intermediate
Intermediates
Polymerization promoter
Processing aids not otherwise specified
Processing aids, not otherwise listed
Viscosity modifiers

Consumer Uses:
Intermediate
Polymerization promoter

Industrial Processes with risk of exposure:
Semiconductor Manufacturing

Applications of Hexamethyldisilazane:
Hexamethyldisilazane is used as a solvent in organic synthesis and organometallic chemistry.
Hexamethyldisilazane is often used as an adhesion promoter for photoresist in photolithography.
Further, Hexamethyldisilazane is used for the preparation of trimethylsilyl ethers from hydroxy compounds.

Hexamethyldisilazane is used as an alternative to critical point drying during sample preparation in electron microscopy.
Hexamethyldisilazane is added to analyte to get silylated diagnostic products during pyrolysis in gas chromatography- mass spectrometry.

Hexamethyldisilazane can be used:
As a silylating agent in the trimethylsilylation of alcohols under nearly neutral reaction conditions.
To control the molecular weights of polypeptides during ring-opening polymerization of α-amino acid N-carboxyanhydrides.

To fabricate silicon carbonitride thin films by plasma-enhanced CVD.
For specimen preparation for scanning electron microscopy and the preparation of trimethylsilyl ethers from hydroxy compounds.

Silanization of glass surfaces:
Glass microscope slides can be made hydrophobic using Hexamethyldisilazane.
The procedure is simple and works quite well.

Place the slides, separated, in a wide mouth glass jar preferable with a PTFE lined cap.
Add a few drops of the Hexamethyldisilazane which will then vaporize in the sealed jar reacting with the surface of the slides.
Better results are obtained if this is done while keeping the jar at 70° for twelve hours, but with the cap slightly ajar.

At the end of the twelve hours, remove the slides.
Water droplets will now "bead up" on the slide surfaces.
The layer responsible for the hydrophobic behavior with we less than one nm in thickness and will also be completely invisible to the eye.

Applications in semiconductor technology:
Hexamethyldisilazane is an outstanding adhesion promoter especially in terms of improving the adhesion of photoresist to the wafer surface.
Hexamethyldisilazane is deposited on the wafer surface prior to the deposition of resist.

Applications in nanotechnology:
The preparation of non-interacting and non-touching nanoparticles is one of the biggest challenges faced by workers in this field of research.
For those interested in the controlled synthesis of non-aggregated nanoparticles with diameters between 1 and 50 nm, one can synthesize nanosize SiO2 particles from Hexamethyldisilazane as precursor and oxygen as the oxidizing agent.

Features and Benefits of Hexamethyldisilazane:
High chemicalstability and low molecular weight
Nontoxic andcost-effective reagent

Ammonia is theonly byproduct generated during silylation
Silylationreaction using HDMS is nearly neutral and does not need any precaution

Properties of Hexamethyldisilazane:

Chemical Properties:
Hexamethyldisilazane, also known as HMDS, is an important organosilicon compound, a colorless and transparent liquid.
Hexamethyldisilazane is readily hydrolyzed and gives off NH3 to produce hexamethyldisilyl ether.

In the presence of a catalyst, Hexamethyldisilazane reacts with alcohols or phenols to produce trimethylalkoxysilane or trimethylaroxysilane.
Reacts with anhydrous hydrogen chloride, releasing NH3 or NH4Cl, to produce trimethylchlorosilane.

Physical properties:
Colorless transparent and easy flowing liquid.
Boiling point 125℃, relative density 0.76 (20/4℃).
Soluble in organic solvents, Hexamethyldisilazane will be rapidly hydrolyzed in contact with air to form trimethylsilanol and hexamethyldisilyl ether.

Synthesis and Derivatives of Hexamethyldisilazane:

Bis(trimethylsilyl)amine is synthesized by treatment of trimethylsilyl chloride with ammonia:
2 (CH3)3SiCl + 3 NH3 → [(CH3)3Si]2NH + 2 NH4Cl

Ammonium nitrate together with triethylamine can be used instead.
This method is also useful for 15N isotopic enrichment of Hexamethyldisilazane.

Alkali metal bis(trimethylsilyl)amides result from the deprotonation of bis(trimethylsilyl)amine.

For example, lithium bis(trimethylsilyl)amide (LiHMDS) is prepared using n-butyllithium:
[(CH3)3Si]2NH + BuLi → [(CH3)3Si]2NLi + BuH

LiHMDS and other similar derivatives: sodium bis(trimethylsilyl)amide (NaHMDS) and potassium bis(trimethylsilyl)amide (KHMDS) are used as a non-nucleophilic bases in synthetic organic chemistry.

General Manufacturing Information of Hexamethyldisilazane:

Industry Processing Sectors:
Adhesive Manufacturing
All Other Basic Inorganic Chemical Manufacturing
All Other Basic Organic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing
Computer and Electronic Product Manufacturing
Electrical Equipment, Appliance, and Component Manufacturing
Other (requires additional information)
Paint and Coating Manufacturing
Pharmaceutical and Medicine Manufacturing
Plastics Material and Resin Manufacturing
Printing and Related Support Activities
Rubber Product Manufacturing
Synthetic Rubber Manufacturing

Stability and Reactivity of Hexamethyldisilazane:

Reactivity:
None known, based on information available.

Chemical stability:
Stable under normal conditions, Moisture sensitive.

Possibility of hazardous reactions

Hazardous Polymerization:
Hazardous polymerization does not occur.

Hazardous Reactions:
None under normal processing.

Conditions to avoid:
Incompatible products.
Excess heat.

Keep away from open flames, hot surfacesandsources of ignition.
Exposure to moist air or water.

Incompatible materials:
Strong oxidizing agents.
Water.

Hazardous decomposition products:
Carbon monoxide (CO).
Carbon dioxide (CO2).

Handling and Storage of Hexamethyldisilazane:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling Hexamethyldisilazane must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do Hexamethyldisilazane without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb with earth, sand or other non-combustible material.
For hydrazine, absorb with DRY sand or inert absorbent (vermiculite or absorbent pads).
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

First Aid Measures of Hexamethyldisilazane:
Call 911 or emergency medical service.
Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves.

Move victim to fresh air if Hexamethyldisilazane can be done safely.
Give artificial respiration if victim is not breathing.

Do not perform mouth-to-mouth resuscitation if victim ingested or inhaled Hexamethyldisilazane; wash face and mouth before giving artificial respiration.
Use a pocket mask equipped with a one-way valve or other proper respiratory medical device.

Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes.

In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes.
In case of burns, immediately cool affected skin for as long as possible with cold water.

Do not remove clothing if adhering to skin.
Keep victim calm and warm.
Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed.

Fire Fighting of Hexamethyldisilazane:
Some of these materials may react violently with water.

SMALL FIRE:
Dry chemical, CO2, water spray or alcohol-resistant foam.

LARGE FIRE:
Water spray, fog or alcohol-resistant foam.
If Hexamethyldisilazane can be done safely, move undamaged containers away from the area around the fire.

Dike runoff from fire control for later disposal.
Do not get water inside containers.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out.

Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

For massive fire, use unmanned master stream devices or monitor nozzles.
If this is impossible, withdraw from area and let fire burn.

Accidental Release Measures of Hexamethyldisilazane:

IMMEDIATE PRECAUTIONARY MEASURE:
Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

SPILL:
Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions.
Also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Disposal Methods of Hexamethyldisilazane:
The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination.
Recycle any unused portion of the material for Hexamethyldisilazane approved use or return Hexamethyldisilazane to the manufacturer or supplier.

Ultimate disposal of the chemical must consider:
The material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Preventive Measures of Hexamethyldisilazane:
The scientific literature for the use of contact lenses in industry is conflicting.
The benefit or detrimental effects of wearing contact lenses depend not only upon Hexamethyldisilazane, but also on factors including the form of Hexamethyldisilazane, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses.
However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye.

In those specific cases, contact lenses should not be worn.
In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Identifiers of Hexamethyldisilazane:
CAS Number: 999-97-3
Abbreviations: HMDS
Beilstein Reference: 635752
ChEBI: CHEBI:85068
ChemSpider: 13238
ECHA InfoCard: 100.012.425
EC Number: 213-668-5
MeSH: Hexamethylsilazane

PubChem CID:
13838
18913873 amine
45051731 sodium
45051783 potassium

RTECS number: JM9230000
UNII: H36C68P1BH
UN number: 2924, 3286
CompTox Dashboard (EPA): DTXSID2025395
InChI: InChI=1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
Key: FFUAGWLWBBFQJT-UHFFFAOYSA-N check
InChI=1/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
Key: FFUAGWLWBBFQJT-UHFFFAOYAF

SMILES:
C[Si](C)(C)N[Si](C)(C)C
N([Si](C)(C)C)[Si](C)(C)C

Synonym(s): Bis(trimethylsilyl)amine, HMDS
Linear Formula: (CH3)3SiNHSi(CH3)3
CAS Number: 999-97-3
Molecular Weight: 161.39
Beilstein: 635752
EC Number: 213-668-5
MDL number: MFCD00008259
PubChem Substance ID: 24867576
NACRES: NA.23

EC Number: 213-668-5
EC Name: 1,1,1,3,3,3-hexamethyldisilazane
CAS Number: 999-97-3
Molecular formula: C6H19NSi2
IUPAC Name: bis(trimethylsilyl)amine

CAS number: 999-97-3
EC number: 213-668-5
Hill Formula: C₆H₁₉N Si₂
Molar Mass: 133.49 g/mol
HS Code: 2931 90 00

CAS: 999-97-3
Molecular Formula: C6H19NSi2
Molecular Weight (g/mol): 161.395
MDL Number: MFCD00008259
InChI Key: FFUAGWLWBBFQJT-UHFFFAOYSA-N
PubChem CID: 13838
ChEBI: CHEBI:85068
IUPAC Name: [dimethyl-(trimethylsilylamino)silyl]methane
SMILES: C[Si](C)(C)N[Si](C)(C)C

Properties of Hexamethyldisilazane:
Chemical formula: C6H19NSi2
Molar mass: 161.395 g·mol−1
Appearance: Colorless liquid
Density: 0.77 g cm−3
Melting point: −78 °C (−108 °F; 195 K)
Boiling point: 126 °C (259 °F; 399 K)
Solubility in water: Slow hydrolysis
Refractive index (nD): 1.4090

Boiling point: 126 °C (1013 mbar)
Density: 0.77 g/cm3 (20 °C)
Explosion limit: 0.8 - 25.9 %(V)
Flash point: 11.4 °C
Ignition temperature: 325 °C
Melting Point: -82 °C
pH value: >7.0 (H₂O)
Vapor pressure: 1900 Pa (20 °C)
Viscosity kinematic: 0.9 mm2/s (25 °C)

Melting point: -78 °C
Boiling point: 125 °C (lit.)
Density: 0.774 g/mL at 25 °C(lit.)
vapor density: 4.6 (vs air)
vapor pressure: 20 hPa (20 °C)
refractive index: n20/D 1.407(lit.)
Flash point: 57.2 °F
storage temp.: Store below +30°C.
solubility: Miscible with acetone, benzene, ethyl ether, heptane and perchloroethylene.
pka: 30(at 25℃)
form: Liquid
color: Colorless
Specific Gravity: 0.774
Odor: Ammonia odour
PH Range: 8.5
Evaporation Rate: < 1
Viscosity: 0.9mm2/s
explosive limit: 0.8-25.9%(V)
Water Solubility: REACTS
Sensitive: Moisture Sensitive
Hydrolytic Sensitivity: 7: reacts slowly with moisture/water
Merck: 14,4689
BRN: 635752
InChIKey: FFUAGWLWBBFQJT-UHFFFAOYSA-N
LogP: 0.23-1.19 at 20-25℃

Grade: reagent grade
Quality Level: 300
Assay: ≥99%
Form: liquid
Refractive index: n20/D 1.407 (lit.)
bp: 125 °C (lit.)
SMILES string: C[Si](C)(C)N[Si](C)(C)C
InChI: 1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
InChI key: FFUAGWLWBBFQJT-UHFFFAOYSA-N

Molecular Weight: 161.39
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 2
Exact Mass: 161.10560268
Monoisotopic Mass: 161.10560268
Topological Polar Surface Area: 12 Ų
Heavy Atom Count: 9
Complexity: 76.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Hexamethyldisilazane:
Assay (GC, area%): ≥ 98 %
Density (d 20 °C/ 4 °C): 0.774 - 0.775
Identity (IR): passes test

Melting Point: -78°C
Density: 0.774
Boiling Point: 126°C
Flash Point: 8°C (46°F)
Assay Percent Range: 98+%
Linear Formula: (CH3)3SiNHSi(CH3)3
Odor: Odorless
UN Number: UN3286
Beilstein: 635752
Merck Index: 14,4689
Refractive Index: 1.408
Quantity: 100 mL
Solubility Information: Miscible with methanol,chloroform,ethyl ether and benzene. Immiscible with water.
Sensitivity: Moisture sensitive
Formula Weight: 161.4
Percent Purity: ≥98%
Physical Form: Liquid
Chemical Name or Material: Hexamethyldisilazane

Related Products of Hexamethyldisilazane:
Disperse Red 1 (Technical Grade)
Disperse Red 1-D3
4-(4-Diethylaminostyryl)-1-methylpyridinium iodide
Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium Chloride (40-50 wt. % in methanol)
1,1′-Diethyl-4,4′-cyanine Iodide

Names of Hexamethyldisilazane:

Preferred IUPAC name:
1,1,1-Trimethyl-N-(trimethylsilyl)silanamine

Trade names:
1,1,1,3,3,3-Hexamethyldisilazan
A-166
Dow Corning(R) 4-2839 INT (PL fluid)
Dow Corning(R) Z-6079 silazane
Dynasylan(R) HMDS
Hexamethyldisilazane
SC3100Z
SH4002ZNC911
SH8270U
SH9151U
SH9161U
SL2501A
SL3358A
SL3358B
SL7230A
SL7230B
SL7240A
SL7240B
SL7250ATT903
SL7250ATT905
SL7250BTT903
SL7250BTT905
SL7260A
SL7260ATT903
SL7260ATT907
SL7260B
SL7260BTT903
SL7260BTT907
SL7270A
SL7270ATT903
SL7270B
SL7270BTT903
SL8601ACG791
SL8601ACG792
SL8601BCG791
SL8601BCG792
SL8609A
SL8609ACG792
SL8609B
SL8609BCG792
SL8640A
SL8640B
SL9051A
SL9051B
SL9055A
SL9055B
SL9340A
SL9340B
SL9805ARM102
SM8110Z
SM8120Z

Other names:
Bis(trimethylsilyl)azane
Bis(trimethylsilyl)amine
1,1,1,3,3,3-Hexamethyldisilazane
Hexamethyldisilazane
HEXAMETHYLENE TETRAMINE
Hexamine, Formin, Urotropin; 1,3,5,7- Tetraazaadamantane; Ammonioformaldehyde; Aceto HMT; Aminoform; Ammoform; Cystamin; Cystogen; Formamine; Hexaform; Hexamethylenamine; Urotropin; Hexilmethylenamine; HMT; CAS NO:100-97-0
HEXAMETHYLENEDIAMINE
Hexamethylenediamine

CAS Reg. No: 124-09-4
EC Number: 204-679-6
Empirical formula: C6H16N2
Molar mass: 116.21 g/mol
Appearance: Colorless crystals or clear liquid



APPLICATIONS


Hexamethylenediamine is used almost exclusively for the production of polymers, an application that takes advantage of its structure.
Furthermore, Hexamethylenediamine is difunctional in terms of the amine groups and tetra functional with respect to the amine hydrogens.

The great majority of the diamine is consumed by the production of nylon 66 via condensation with adipic acid.
Moreover, Hexamethylenediamine is generated from this diamine by phosgenation as a monomer feedstock in the production of polyurethane.

Hexamethylenediamine also serves as a cross-linking agent in epoxy resins.


Some uses of Hexamethylenediamine:

Materials used for construction (e.g. flooring, tile, sinks, bathtubs, mirrors, wall materials/drywall, wall-to-wall carpets, insulation, playground surfaces); includes semi-permanent fixtures such as faucets and light fixtures
Buffering
Monomer
Polymer
Construction and building materials
Intermediate
Isocyanates
Scale and corrosion inhibitors
Water treatment chemicals
Epoxy curing agents
Polyamide resins, adhesives, inks, fibers
Petroleum additives
Intermediates


Hexamethylenediamine and adipic acid are the starting materials for nylon 6,6 used widely in textiles and plastics.
Besides, Hexamethylenediamine reduce yellowing in PU resin.

Hexamethylenediamine can react with the phosgene and produce the HexamethylenDiIsocyanate (HDI).
The main uses of Hexamethylenediamineare epoxy curing agents, petroleum, adhesives, inks, scale and corrosion inhibitors, water treatment chemicals and disinfectants.

Hexamethylenediamine is moderately toxic.
Besides, Hexamethylenediamine can cause serious burns and severe irritation.

In addition, Hexamethylenediamine can be founded as various grade.

Hexamethylenediamine is one of the largest chemical distributor in Europe.
More to that, Hexamethylenediamine is handling the storage, transport, export & import formalities of Hexamethylenediamine globally.

Hexamethylenediamine can be used as a reagent used to modify acrylonitrile copolymers and to polycondense with compounds such as calcein


Hexamethylenediamine can be used as a:

Reactant for the synthesis of dialkyl hexamethylene-1,6-dicarbamate with alkyl carbamate in the presence of various metal catalysts via the transesterification reaction
Surface modifier for chlorinated and fluorinated nanodiamond synthesized by detonation.
Reactant with adipic acid for the synthesis of nylon 6-6 by polycondensation.


Hexamethylenediamine is used as an intermediate to make polyamides with applications in fiber, plastics, polyurethane coatings and adhesives, specialty nylons (monofilaments and inks), and specialty chemicals (biocides, petroleum additives, and phenol purification).
Further to that, Hexamethylenediamine is used to prepare hexamethylene diisocyanate.

Hexamethylenediamine was first reported by Theodor Curtius.
Additionally, Hexamethylenediamine is produced by the hydrogenation of adiponitrile:
NC(CH2)4CN + 4 H2 → H2N(CH2)6NH2


The hydrogenation is conducted on molten adiponitrile diluted with ammonia, typical catalysts being based on cobalt and iron.
The yield is good, but commercially significant side products are generated by virtue of reactivity of partially hydrogenated intermediates.
These other products include 1,2-diaminocyclohexane, hexamethyleneimine, and the triamine bis(hexamethylenetriamine).

An alternative process uses Raney nickel as the catalyst and adiponitrile that is diluted with hexamethylenediamine itself (as the solvent).
This process operates without ammonia and at lower pressure and temperature.

Hexamethylenediamine’s primary use is for manufacturing unmodified resins, water treatment resins, resins used in paper manufacture and adhesive resins.
Other applications of Hexamethylenediamine include use as an intermediate to make polyamides with applications in fiber, plastics, polyurethane coatings and adhesives, specialty nylons (monofilaments and inks), and specialty chemicals (biocides, petroleum additives, and phenol purification).

Hexamethylenediamine is solely an industrial product, not designed for consumer use.
Furthermore, Hexamethylenediamine is produced by the hydrogenation of adiponitrile.


Main uses of Hexamethylenediamine are as a raw material in the:

Production of nylon polymers
Production of hexamethylene diisocyanate (HDI) for use as monomer feedstock in polyurethane production
Cross-link agent in epoxy resins.



DESCRIPTION


Hexamethylenediamine (formally hexane-1,6-diamine) is a colorless, low-melting solid with an important industrial use.
Moreover, Hexamethylenediamine and adipic acid (Molecule of the Week for February 9, 2015) are the starting materials for manufacturing nylon 6,6, a polyamide used widely in textiles and plastics.

The earliest synthesis of hexamethylenediamine is attributed to Theodor Curtius and Hans Clemm, Heidelberg University (Germany) chemists, who in 1900 made it by hydrogenating adiponitrile.
In 1929, biochemists Karl H. Slotta and R. Tschesche at the University of Breslau (Germany) improved this process by generating hydrogen in situ from sodium metal and ethanol.

Hexamethylenediamine market value in 2018 is estimated to be more than US$3 billion; this value is expected to double by 2026.

Hexamethylenediamine is the organic compound with the formula H2N(CH2)6NH2.
The molecule of Hexamethylenediamine is a diamine, consisting of a hexamethylene hydrocarbon chain terminated with amine functional groups.

Hexamethylenediamine is in the form of colorless solid (yellowish for some commercial samples).
Besides, Hexamethylenediaminehas a strong amine odor.

About 1 billion kilograms of Hexamethylenediamine are produced annually.
Hexamethylenediamine solution appears as a clear colorless liquid.

Hexamethylenediamine burns although some effort is required to ignite.
In addition, Hexamethylenediamine is soluble in water.

Hexamethylenediamine is corrosive to metals and tissue.
More to that, Hexamethylenediamine produces toxic oxides of nitrogen during combustion.

Hexamethylenediamine is used to make nylon.
More to that, Hexamethylenediamine is a colorless crystalline solid.

Hexamethylenediamine is soluble in water.
Further to that, Hexamethylenediamine is corrosive to metals and tissue.

Hexamethylenediamine produces toxic oxides of nitrogen during combustion.
Hexane-1,6-diamine is a C6 alkane-alpha,omega-diamine.

Hexamethylenediamine has a role as a human xenobiotic metabolite.
Additionally, Hexamethylenediamine derives from a hydride of a hexane.

Hexamethylenediamine is corrosive to metals and tissue.
Furthermore, Hexamethylenediamine produces toxic oxides of nitrogen during combustion.


Different methods of production of Hexamethylenediamine:

Hexamethylenediamine from butadiene via adiponitrile (ADN) by hydrocyanation
Moreover, Hexamethylenediamine from acrylonitrile via ADN by electrohydrodimerization
Hexamethylenediamine from adipic acid via ADN by ammoniation and hydrogenation


World production of Hexamethylenediamine in 1995 was estimated at 1.19 million tons (2.62 billion pounds), of which 90% was accounted for by demand in the United States, Western Europe, Japan, and Canada.
The average growth in Hexamethylenediamine demand through 2001, is estimated at 2.2%/yr in the United States, 2.5% in Western Europe, 2.4% in Japan, and 2.3% in Canada.
As of January 1996, world Hexamethylenediamine production capacity was estimated at 1.33 million t/yr (2.93 billion lb/yr).

In addition to its use in the production of nylon 66 fibers and resins, Hexamethylenediamine is reacted with other dicarboxylic acids to make nylon 69, nylon 610, and nylon 612.
In addition, Hexamethylenediamine can be used as a hardener for epoxy resins, in the production of hexamethylene diisocyanate for weather-resistant polyurethane, and of HDMA carbamate as an accelerator in fluorinated and polyacrylate elastomer vulcanization.

Hexamethylenediamine is a colorless crystalline solid organic compound with the molecular formula C6H16N2.
Its CAS number of Hexamethylenediamine is 124-09-4.

The Hexamethylenediamine molecule is soluble in water and corrosive to metals and tissue.
During combustion, Hexamethylenediamine produces toxic oxides of nitrogen and has a strong amine odor.

Hexamethylenediamine is used almost exclusively for the manufacture and production of polymers.


Economics for the following alternative routes to Hexamethylenediamine:

Hexamethylenediamine from butadiene via adiponitrile (ADN) by hydrocyanation
Besides, Hexamethylenediamine from acrylonitrile via ADN by electrohydrodimerization
Hexamethylenediamine from adipic acid via ADN by ammoniation and hydrogenation

World production of Hexamethylenediamine in 1995 was estimated at 1.19 million tons (2.62 billion pounds), of which 90% was accounted for by demand in the United States, Western Europe, Japan, and Canada.
The average growth in Hexamethylenediamine demand through 2001, is estimated at 2.2%/yr in the United States, 2.5% in Western Europe, 2.4% in Japan, and 2.3% in Canada.
As of January 1996, world HMDA production capacity was estimated at 1.33 million t/yr (2.93 billion lb/yr).

In addition to its use in the production of nylon 66 fibers and resins, Hexamethylenediamine is reacted with other dicarboxylic acids to make nylon 69, nylon 610, and nylon 612.
In addition, Hexamethylenediamine can be used as a hardener for epoxy resins, in the production of hexamethylene diisocyanate for weather-resistant polyurethane, and of Hexamethylenediamine carbamate as an accelerator in fluorinated and polyacrylate elastomer vulcanization.



PROPERTIES


Molecular Weight: 116.20
XLogP3-AA: -0.2
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 5
Exact Mass: 116.131348519
Monoisotopic Mass: 116.131348519
Topological Polar Surface Area: 52 Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 31.5
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Melting point: 42 ºC
Boiling point: 205 ºC
Water solubility: 490 g/L



FIRST AID


General advice:

First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.


If inhaled

After inhalation: fresh air.
Call in physician.
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.

If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown atmosphere.
Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.


In case of skin contact:

Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water.
IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop.
IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.


In case of eye contact:

Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.

First check the victim for contact lenses and remove if present.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.


If swallowed:

Make victim drink water (two glasses at most), avoid vomiting (risk of perforation).
Call a physician immediately.
Do not attempt to neutralise.

DO NOT INDUCE VOMITING.
Corrosive chemicals will destroy the membranes of the mouth, throat, and esophagus and, in addition, have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems.
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center.

IMMEDIATELY transport the victim to a hospital.
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body.

DO NOT INDUCE VOMITING.
Transport the victim IMMEDIATELY to a hospital.


Indication of any immediate medical attention and special treatment needed:

No data available



HANDLING AND STORAGE


Precautions for safe handling:
Advice on safe handling:

Work under hood.
Do not inhale substance/mixture.
Advice on protection against fire and explosion.
Keep away from open flames, hot surfaces and sources of ignition.
Take precautionary measures against static discharge.


Hygiene measures:

Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.


Conditions for safe storage, including any incompatibilities:

Storage conditions
Tightly closed.
Dry.
Hygroscopic.
Store under inert gas.

Storage class:
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials.


Specific end use(s):

Apart from the uses mentioned above no other specific uses are stipulated.



SYNONYMS


1,6-Hexanediamine
1,6-Diaminohexane
Hexamethylenediamine
124-09-4
HEXANE-1,6-DIAMINE
HMDA
1,6-Hexylenediamine
1,6-Hexamethylenediamine
1,6-Diamino-n-hexane
HEXAMETHYLENE DIAMINE
Hexylenediamine
diaminohexane
NCI-C61405
1,6-Hexanediamine (solution)
HEX-NH2
NSC 9257
H2N(CH2)6NH2
ZRA5J5B2QW
CHEMBL303004
Amides, vegetable-oil, N,N'-hexanediylbis-
CHEBI:39618
NSC-9257
DSSTox_CID_4922
DSSTox_RID_77583
DSSTox_GSID_24922
73398-58-0
Hexane, 1,6-diamino-
16D
CAS-124-09-4
CCRIS 6224
HSDB 189
EINECS 204-679-6
UNII-ZRA5J5B2QW
MFCD00008243
UN1783
UN2280
Hexamethylenediamine solution
BRN 1098307
AI3-37283
1,6diaminohexane
6-aminohexylamine
1,6 diaminohexane
1,6 hexanediamine
1.6-diaminohexane
1,6-diamino hexane
1,6-hexamethylene diamine
Hexamethylenediamine, solid
Hexamethylenediamine, 98%
EC 204-679-6
WLN: Z6Z
Hexamethylene diamine, solid
NCIOpen2_002722
SCHEMBL15085
Hexamethylenediamine, solution
4-04-00-01320 (Beilstein Handbook Reference)
HEXANEMETHYLENEDIAMINE-
UN 1783 (Salt/Mix)
1,6-Hexandiamine, vegetable oil fatty acids diamide
Hexamethylene diamine, solution
Hexamethylenediamine, solution [UN1783] [Corrosive]
SCHEMBL7090279
DTXSID5024922
1,6-HEXANEDIAMINE [MI]
NSC9257
1,6-HEXANEDIAMINE [INCI]
ZINC1543408
HEXAMETHYLENE DIAMINE [HSDB]
Tox21_202088
Tox21_303123
BBL027705
BDBM50323740
STL281875
AKOS000118875
DB03260
UN 2280
NCGC00091677-01
NCGC00091677-02
NCGC00257104-01
NCGC00259637-01
BP-21415
VS-08580
Hexamethylenediamine, technical grade, 70%
D0095
FT-0606994
FT-0666352
EN300-19313
AG-690/11351767
Hexamethylenediamine, SAJ first grade, >=98.0%
Q424936
Hexamethylenediamine, solid [UN2280] [Corrosive]
Hexane-1,6-diamine 100 microg/mL in Acetonitrile
J-504038
Z104473514
HEXAMETHYLENEGLYCOL
Hexamethyleneglycol is a waxy hygroscopic solid compound that is white in colour.
Hexamethyleneglycol is a linear diol that contains two primary hydroxyl groups that are located at the terminal.
Hexamethyleneglycol’s linear hydrocarbon chain enables the compound to have enhanced hardness and flexibility of polyesters.

CAS: 629-11-8
MF: C6H14O2
MW: 118.17
EINECS: 211-074-0

Moreover, this property is utilized in the extending chains in polyurethanes.
A diol that is hexane substituted by hydroxy groups at positions 1 and 6.
Hexamethyleneglycol is an organic compound with the formula (CH2CH2CH2OH)2.
Hexamethyleneglycol is a colorless water-soluble solid.
Hexamethyleneglycol is famous for its excellent solvency among a wide variety of materials and is popular in skin care formulas due to its ability to improve the texture.
Hexamethyleneglycol has viscosity-reducing properties that allow it to thin out heavy, thick formulations and produce smooth spreadability.
Studies indicate Hexamethyleneglycol also exhibits antimicrobial properties.
In addition to skin care, hexylene glycol is used in other beauty products including hair care and makeup.

Hexamethyleneglycol also goes by its chemical compound name: 2-Methyl-2,4-pentanediol.
As a raw material, Hexamethyleneglycol is a clear liquid.
Hexamethyleneglycol is often used in preservative blends that contain phenoxyethanol because it boosts the efficacy of this preservative, allowing lower amounts to be used, which reduces the risk skin will have a sensitised response.
Hexamethyleneglycol has been backed as a safe ingredient for decades with reported concentrations up to 25% in personal care products (though most skin care formulas use much lower amounts than that, especially in preservative blends).
Hexamethyleneglycol is a clear liquid with a mild, sweet odour most commonly used in cosmetics and personal care products in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.
Hexamethyleneglycol helps to improve the texture and sensory feel of the formulation, functioning as a surfactant to cleanse and moisturize the skin, as an emulsifier and a viscosity-reducing agent to improve absorption and allow other ingredients to work better.

Hexamethyleneglycol or HG is an oxygenated solvent derived from acetone which has two alcohol functions.
Hexamethyleneglycol has a low evaporation rate and it is completely miscible with water.
Hexamethyleneglycol is mainly used as a solvent or coupling agent.
Hexamethyleneglycol is a potential substitute for glycol ethers.
Hexamethyleneglycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexamethyleneglycol can also be used as a building block in chemical synthesis.
Hexamethyleneglycol is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.
Hexylene glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.
Hexamethyleneglycol is fully miscible in water and has the chemical formula C6H14O2.
Hexamethyleneglycol is a compound that appears in a large number of products that are used commercially and industrially.

Hexamethyleneglycol Chemical Properties
Melting point: 38-42 °C (lit.)
Boiling point: 250 °C (lit.)
density: 0.96
vapor pressure: 0.53 mm Hg ( 20 °C)
refractive index: 1.457
Fp: 215 °F
storage temp.: Store below +30°C.
solubility H2O: 0.1 g/mL, clear, colorless
form: Waxy Flakes
pka: 14.87±0.10(Predicted)
color: White
PH: 7.6 (900g/l, H2O, 20℃)
explosive limit: 6.6-16%(V)
Water Solubility: 500 g/L
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1
Merck: 14,4690
BRN: 1633461
InChIKey: XXMIOPMDWAUFGU-UHFFFAOYSA-N
LogP: 0 at 25℃
CAS DataBase Reference: 629-11-8(CAS DataBase Reference)
NIST Chemistry Reference: 1,6-Hexanediol(629-11-8)
EPA Substance Registry System: Hexamethyleneglycol (629-11-8)

As Hexamethyleneglycol contains the hydroxyl group, it undergoes the typical chemical reactions of alcohols such as dehydration, substitution, esterification.
Dehydration of Hexamethyleneglycol gives oxepane, 2-methyltetrahydropyran and 2-ethyltetrahydrofuran.
Corresponding thiophene and pyrrolidone can be made by reacting Hexamethyleneglycol with hydrogen sulfide and ammonia respectively.

Uses and Applications
Solvent, intermediate for high polymers (nylon, polyesters), coupling agent, coil coating.
Hexamethyleneglycol is used in polymer synthesis such as polyester, polyurethane and nylon.
Hexamethyleneglycol is used as an intermediate to adhesives, acrylics and dyestuffs.
Further, Hexamethyleneglycol is employed in gasoline refining and pharmaceutical production.
Hexamethyleneglycol is widely used for industrial polyester and polyurethane production.
Hexamethyleneglycol can improve the hardness and flexibility of polyesters as it contains a fairly long hydrocarbon chain.
In polyurethanes, Hexamethyleneglycol is used as a chain extender, and the resulting modified polyurethane has high resistance to hydrolysis as well as mechanical strength, but with a low glass transition temperature.
Hexamethyleneglycol is also an intermediate to acrylics as a crosslinking agent, e.g. hexanediol diacrylate.
Unsaturated polyester resins have also been made from 1,6-hexanediol, along with styrene, maleic anhydride and fumaric acid.
Hexamethyleneglycol is used in cosmetics and personal care products such as hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.

The single largest user of hexylene glycol is the industrial coatings industry which uses approximately 45% of the HGL produced world-wide.
Hexamethyleneglycol is a component in lacquers and varnishes, and is a solvent plasticiser in surface coatings.
Hexamethyleneglycol is also a component in both oil and water- based paints, and in paint strippers.
Hexamethyleneglycol is also used as a chemical intermediate, which accounts for approximately 20% of its consumption, and another 10% is used on oil and natural-gas fields where Hexamethyleneglycol is both a down hole lubricant, and a grinding and extraction aid.
Hexamethyleneglycol is also employed as an antifreeze, and as a coupling agent for hydraulic fluids.
Hexamethyleneglycol is a moisturising, and setting, agent in the manufacture of textiles and can also be found in the cosmetics industry where it is a component of fragrances and bath, hair, and soap preparations.
Hexamethyleneglycol also has a role as a wetting agent in pesticide formulations and is a solvent in the preparation of dyes.

Uses to study biomolecular condensates
Hexamethyleneglycol has been used to characterize biomolecular condensates.
The material properties of condensates can be examined to determine if they are solid or liquid condensates.
Hexamethyleneglycol has been reported to interfere with weak hydrophobic protein-protein or protein-RNA interactions that comprise liquid condensates.
Hexamethyleneglycol has been reported to dissolve liquid but not solid condensates.
2,5 hexanediol or 1,4-butanediol has been observed to have minimal effect on behavior of disorderd proteins as compared to Hexamethyleneglycol.

Polyurethanes
Hexamethyleneglycol is widely utilized in the manufacture of polyesterols such as sebacates, azelates, and adipates.
These compounds are resistant to hydrolysis and have low glass transition temperature as well as high mechanical levels.
Hexamethyleneglycol is used as an ingredient in the preparation of a wide range of tailor-made products for numerous specialty and standard applications.
Hexamethyleneglycol can be used for a variety of applications such as:
a structure-directing agent for the synthesis of ZSM-5 zeolite
a solvent for titanium tetraisopropoxide to form titanium oxide (TiO2) nanocrystals
a phase change material in combination with lauric acid for thermal energy storage applications

In Acrylics
Hexamethyleneglycol is utilized as an ingredient in the manufacture of the bifunctional hexanediol diacrylate which is a monomer that is normally used in conjunction with other acrylic monomers as a reactive diluent for decorative coatings and printing inks.

In Adhesives
Urethanes and co-terephthalates that are based on Hexamethyleneglycol provide faster better tack properties and crystallization.
Due to its low glass transition property, Hexamethyleneglycol offers high flexibility as well as excellent adhesive properties.

Other Uses
Hexamethyleneglycol is incorporated into the production of other compounds used in polymeric thickeners, sizing agents, plasticizers for polyvinyl chloride, pesticides, and surfactants dyestuffs as a flexible building block.

Preparation
Hexamethyleneglycol is produced by a propriety process that is based on BASF technology.
Industrially, Hexamethyleneglycol is prepared by the hydrogenation of adipic acid.
Conversely, in the laboratory, Hexamethyleneglycol can be synthesized by the reduction of adipic acid with lithium aluminum hydride.

Quality and Analysis
The assay of the pure product is about 98 %; impurities are various diols and -caprolactone as well as traces of water.
The color number of the product determined photometrically according to the Pt/Co scale must not exceed 15 APHA.
Above 70 ℃, Hexamethyleneglycol tends to turn yellow.

Production
Hexamethyleneglycol is prepared by the hydrogenation of adipic acid or its esters.
Laboratory preparation could be achieved by reduction of adipates with lithium aluminium hydride, although this method is impractical on a commercial scale.

Production Methods
Hexamethyleneglycol is produced industrially by the catalytic hydrogenation of adipic acid or of its esters.
Mixtures of dicarboxylic acids and hydroxycarboxylic acids with C6 components formed in other processes (e.g., in cyclohexane oxidation) are also used.
Esterifification of "distillation heavies" with lower alcohols is often carried out before hydrogenation.
The acids are hydrogenated continuously at 170-240 ℃ and at 15.0-30.0 MPa on a suitable catalyst either in a trickle-flflow (downflflow) or a bubble-flflow (upflflow) fifixed-bed reactor.

The reactor temperature is controlled by circulating part of the reactor discharge.
The hydrogen required for the hydrogenation is fed together with the recycle gas through the recycle gas compressor to the reactor.
Side products of the synthesis are alcohols, ethers, diols, and esters.
Pure Hexamethyleneglycol is obtained by fractional distillation of the crude reactor discharge.
For the hydrogenation of dicarboxylic acids, catalysts containing cobalt, copper, or manganese are suitable.
For the hydrogenation of esters, catalysts such as copper chromite or copper with added zinc and barium are used as "full catalysts" or on inert carriers.
Ruthenium, platinum, or palladium on inert supports can also be used.
Gas-phase hydrogenation of esters of adipic or 6-hydroxyhexanoic acid can be carried out at 1-7 MPa.
Both acids and esters also may be hydrogenated using suspended catalysts.
Oligomeric esters of the product diol and adipic acid can also be hydrogenated.

Synonyms
Hexylene glycol
2-METHYL-2,4-PENTANEDIOL
107-41-5
2-Methylpentane-2,4-diol
Diolane
Pinakon
2,4-Pentanediol, 2-methyl-
2,4-Dihydroxy-2-methylpentane
Isol
4-Methyl-2,4-pentanediol
1,1,3-Trimethyltrimethylenediol
Caswell No. 574
2-Methyl pentane-2,4-diol
2-Methyl-2,4-pentandiol
hexyleneglycol
HSDB 1126
UNII-KEH0A3F75J
(+-)-2-Methyl-2,4-pentanediol
NSC 8098
NSC-8098
EINECS 203-489-0
KEH0A3F75J
alpha,alpha,alpha'-Trimethyltrimethylene glycol
EPA Pesticide Chemical Code 068601
BRN 1098298
1,3-dimethyl-3-hydroxybutanol
CCRIS 9439
DTXSID5021885
CHEBI:62995
AI3-00919
Hexylene glycol [NF]
1,3,3-trimethyl-1,3-propanediol
TRACID RUBINE 5BL
DTXCID101885
EC 203-489-0
1,1,3-trimethyl-1,3-propanediol
4-01-00-02565 (Beilstein Handbook Reference)
Hexylene glycol (NF)
HEXYLENE GLYCOL (II)
HEXYLENE GLYCOL [II]
7-MethylAtracuriumDimesylate(MixtureofDiastereomers)
MPD
HEXYLENE GLYCOL (MART.)
HEXYLENE GLYCOL [MART.]
HEXYLENE GLYCOL (USP-RS)
HEXYLENE GLYCOL [USP-RS]
CAS-107-41-5
2-Methylpentan-2,4-diol
2-Methyl-pentane-2,4-diol
64229-01-2
MFCD00004547
Hexylene glycol, 99%
R-(-)-2-METHYL-2,4-PENTANEDIOL
2methyl-2,4-pentanediol
Hexylene glycol, >=99%
Hexylene glycol, 99.5%
SCHEMBL19379
HEXYLENE GLYCOL [MI]
1,3-Trimethyltrimethylenediol
HEXYLENE GLYCOL [HSDB]
HEXYLENE GLYCOL [INCI]
CHEMBL2104293
NSC8098
(?)-2-Methyl-2,4-pentanediol
SVTBMSDMJJWYQN-UHFFFAOYSA-N
HMS3264E19
HY-B0903
Hexylene glycol, analytical standard
Tox21_201975
Tox21_302818
s3588
AKOS015901459
CCG-213719
WLN: QY1 & 1XQ1 & 1
NCGC00249143-01
NCGC00256494-01
NCGC00259524-01
AC-13749
AS-58339
Hexylene glycol, BioXtra, >=99% (GC)
(+/-)-2-Methyl-2,4-pentanediol, MPD
FT-0605050
FT-0605756
FT-0613069
Hexylene glycol, puriss., >=99.0% (GC)
M0384
(S)-(-)-2-METHYL-2,4-PENTANEDIOL
.alpha.,.alpha.'-Trimethyltrimethylene glycol
Hexylene glycol, BioUltra, >=99.0% (GC)
D04439
EN300-170052
AB01563179_01
J-640306
J-660006
Q2792203
W-108748
Z1255485267
Hexylene glycol, United States Pharmacopeia (USP) Reference Standard
HEXAMETHYLENETETRAMINE
DESCRIPTION:
Hexamethylenetetramine, also known as methenamine, hexamine, or its trade name Urotropin, is a heterocyclic organic compound with the formula (CH2)6N4.
Hexamethylenetetramine is highly soluble in water and polar organic solvents.
Hexamethylenetetramine has a cage-like structure similar to adamantane.

CAS Number, 100-97-0
EC Number, 202-905-8

Hexamethylenetetramine is useful in the synthesis of other organic compounds, including plastics, pharmaceuticals, and rubber additives.
Hexamethylenetetramine sublimes in vacuum at 280 °C.


Hexamethylenetetramine appears as odorless white crystalline powder or colorless lustrous crystals.
Hexamethylenetetramine Sublimes in a vacuum at about 505 °F with some decomposition.
Solutions are strong bases (pH of 0.2 molar aqueous solution is 8.4).


Hexamethylenetetramine is a polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.
Hexamethylenetetramine has a role as an antibacterial drug.
Hexamethylenetetramine is a polycyclic cage, a polyazaalkane and a tetramine.


Hexamethylenetetramine is a heterocyclic organic compound with a cage-like structure similar to adamantane.
In salt form Hexamethylenetetramine is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).







SYNTHESIS, STRUCTURE, REACTIVITY OF HEXAMETHYLENETETRAMINE:
Hexamethylenetetramine was discovered by Aleksandr Butlerov in 1859.
Hexamethylenetetramine is prepared industrially by combining formaldehyde and ammonia:
The reaction can be conducted in gas phase and in solution.


The molecule has a tetrahedral cage-like structure, similar to adamantane.
Four vertices are occupied by nitrogen atoms, which are linked by methylene groups.
Although the molecular shape defines a cage, no void space is available at the interior for binding other atoms or molecules, unlike crown ethers or larger cryptand structures.


The molecule behaves like an amine base, undergoing protonation and N-alkylation (e.g. quaternium-15).

APPLICATIONS OF HEXAMETHYLENETETRAMINE:
The dominant use of hexamethylenetetramine is in the production of powdery or liquid preparations of phenolic resins and phenolic resin moulding compounds, where it is added as a hardening component.
These products are used as binders, e.g. in brake and clutch linings, abrasive products, non-woven textiles, formed parts produced by moulding processes, and fireproof materials.

Industry Uses:
Hexamethylenetetramine is dominantly used in the production of powdery or liquid preparations of phenolic resins and phenolic resin molding compounds where it is added as a hardening component.
These products are used as binders in the manufacture of brake and clutch linings, abrasive products, non-woven textiles, formed parts produced by molding processes, and fireproof materials.
Hexamethylenetetramine is also used in the medical profession for the treatment of urinary tract infections.

Because Hexamethylenetetramine is smokeless when burned, has a high energy density of 30.0 megajoules per kilogram (MJ/kg), does not liquify while burning, and leaves no ashes, hexamethylenetetramine is a component of hexamine fuel tablets used by campers, hobbyists, the military and relief organizations for heating camping food as well as military rations.
The crystalline compound is also used as a reagent in organic chemistry, a food additive as a preservative, and as the base component in the manufacture of certain explosives.





MEDICAL USES OF HEXAMETHYLENETETRAMINE:
As the mandelic acid salt (methenamine mandelate) or the hippuric acid salt (methenamine hippurate), it is used for the treatment of urinary tract infection.
In an acidic environment, methenamine is believed to act as an antimicrobial by converting to formaldehyde.
A systematic review of its use for this purpose in adult women found there was insufficient evidence of benefit and further research is needed.

A UK study showed that methenamine is as effective as daily low-dose antibiotics at preventing UTIs among women who experience recurrent UTIs.
As methenamine is an antiseptic, it may avoid the issue of antibiotic resistance.
Methenamine acts as an over-the-counter antiperspirant due to the astringent property of formaldehyde.


HISTOLOGICAL STAINS OF HEXAMETHYLENETETRAMINE:
Methenamine silver stains are used for staining in histology, including the following types:
Grocott's methenamine silver stain, used widely as a screen for fungal organisms.
Jones' stain, a methenamine silver-Periodic acid-Schiff that stains for basement membrane, availing to view the "spiked" Glomerular basement membrane associated with membranous glomerulonephritis.


Solid fuel:
Together with 1,3,5-trioxane, hexamethylenetetramine is a component of hexamine fuel tablets used by campers, hobbyists, the military and relief organizations for heating camping food or military rations.
It burns smokelessly, has a high energy density of 30.0 megajoules per kilogram (MJ/kg), does not liquify while burning, and leaves no ashes, although its fumes are toxic.[citation needed]
Standardized 0.149 g tablets of methenamine (hexamine) are used by fire-protection laboratories as a clean and reproducible fire source to test the flammability of carpets and rugs.


Food additive:
Hexamethylenetetramine or hexamine is also used as a food additive as a preservative (INS number 239).
Hexamethylenetetramine is approved for usage for this purpose in the EU, where it is listed under E number E239, however it is not approved in the USA, Russia, Australia, or New Zealand.

Reagent in organic chemistry:
Hexamethylenetetramine is a versatile reagent in organic synthesis.
Hexamethylenetetramine is used in the Duff reaction (formylation of arenes), the Sommelet reaction (converting benzyl halides to aldehydes), and in the Delepine reaction (synthesis of amines from alkyl halides).


Explosives:
Hexamethylenetetramine is the base component to produce RDX and, consequently, C-4 as well as octogen (a co-product with RDX), hexamine dinitrate, hexamine diperchlorate and HMTD.


HISTORICAL USES OF HEXAMETHYLENETETRAMINE:
Hexamethylenetetramine was first introduced into the medical setting in 1895 as a urinary antiseptic.
However, it was only used in cases of acidic urine, whereas boric acid was used to treat urinary tract infections with alkaline urine.
Scientist De Eds found that there was a direct correlation between the acidity of hexamethylenetetramine's environment and the rate of its decomposition.

Therefore, its effectiveness as a drug depended greatly on the acidity of the urine rather than the amount of the drug administered.
In an alkaline environment, hexamethylenetetramine was found to be almost completely inactive.
Hexamethylenetetramine was also used as a method of treatment for soldiers exposed to phosgene in World War I.

Subsequent studies have shown that large doses of hexamethylenetetramine provide some protection if taken before phosgene exposure but none if taken afterwards.


SAFETY INFORMATION ABOUT HEXAMETHYLENETETRAMINE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




CHEMICAL AND PHYSICAL PROPERTIES OF HEXAMETHYLENETETRAMINE:
Chemical formula, C6H12N4
Molar mass, 140.186 g/mol
Appearance, White crystalline solid
Odor, Fishy, ammonia like
Density, 1.33 g/cm3 (at 20 °C)
Melting point, 280 °C (536 °F; 553 K) (sublimes)
Solubility in water, 85.3 g/100 mL
Solubility, Soluble in chloroform, methanol, ethanol, acetone, benzene, xylene, ether
Solubility in chloroform, 13.4 g/100 g (20 °C)
Solubility in methanol, 7.25 g/100 g (20 °C)
Solubility in ethanol, 2.89 g/100 g (20 °C)
Solubility in acetone, 0.65 g/100 g (20 °C)
Solubility in benzene, 0.23 g/100 g (20 °C)
Acidity (pKa), 4.89
Molecular Weight
140.19 g/mol
XLogP3-AA
0.3
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
140.106196400 g/mol
Monoisotopic Mass
140.106196400 g/mol
Topological Polar Surface Area
13Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
84.8
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Density, 1.331 g/cm3 (22 °C)
Flash point, 250 °C
Ignition temperature, 390 °C
Melting Point, 280 °C Not applicable
pH value, 7 - 10 (100 g/l, H₂O, 20 °C)
Vapor pressure, Bulk density, 600 kg/m3
Solubility, 895 g/l soluble





SYNONYMS OF HEXAMETHYLENETETRAMINE:
Aminoform
Hexamethylenetetramine
Hexamine
Hexamine Silver
Methenamine
Methenamine Silver
Methenamine, Silver
Silver Methenamine
Silver, Hexamine
Silver, Methenamine
Urotropin
methenamine
Hexamethylenetetramine
100-97-0
Hexamine
Urotropine
Aminoform
Hexamethylenamine
Urotropin
1,3,5,7-Tetraazaadamantane
HMTA
Hexamethylene tetramine
Methenamin
Uritone
Hexamethylenetetraamine
Formamine
Aminoformaldehyde
Ammoform
Ammonioformaldehyde
Antihydral
Cystamin
Cystogen
Duirexol
Hexaform
Metramine
Resotropin
Uratrine
Urodeine
Xametrin
Formin
Heterin
Uramin
Preparation AF
Hexamethyleneamine
Hexilmethylenamine
Hexa-Flo-Pulver
Ekagom H
methenaminum
Hexaloids
Hexaminum
Metenamina
Aceto HMT
Herax UTS
Hexasan
Hexamethylentetramin
Nocceler H
Sanceler H
Formin (heterocycle)
Hexamine (heterocycle)
Vulkacit H 30
Hexamethylentetraminum
Hexamethylentetramine
S 4 (heterocycle)
Hexamethylenetetraminum
Esametilentetramina
Hexasan (VAN)
Methamin
1,3,5,7-Tetraazatricyclo[3.3.1.13,7]decane
Caswell No. 482
Uro-phosphate
Sanceler HT
Heksa K
Hexamine Superfine
Nocceler H-PO
Sanceler HT-PO
Hexa (vulcanization accelerator)
Hexa B
1,3,5,7-tetraazatricyclo[3.3.1.1~3,7~]decane
Cohedur H 30
Rhenogran HEXA 80
Thixon 715B
Metenamine
1,3,5,7-Tetraazatricyclo (3.3.1.1(3,7))decane
CCRIS 2297
HSDB 563
Vesaloin
Urisol
HMT
Metenamina [INN-Spanish]
Methenaminum [INN-Latin]
UNII-J50OIX95QV
EINECS 202-905-8
J50OIX95QV
NSC 26346
NSC-26346
Hexamine (JAN)
Hexamine (TN)
EL 10 (corrosion inhibitor)
EPA Pesticide Chemical Code 045501
NSC 403347
CHEBI:6824
INS NO.239
1,3,5,7-Tetraazatricyclo(3.3.1.13,7)decane
DTXSID6020692
AI3-09611
Hexamethylenetetramine (aliphatic)
INS-239
1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 37))decane
EL 10
Methenamine (USP/INN)
Methenamine [USP:INN]
NSC-403347
DTXCID00692
Silver Methenamine
H.M.T.
E-239
EC 202-905-8
1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane
Formin (the heterocyclic compound)
NSC26346
MFCD00006895
1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 3,7))decane
NCGC00094719-04
E239
HEXAMINE [JAN]
Hexamine Silver
Methenamine (USP:INN)
Metenamina (INN-Spanish)
Methenaminum (INN-Latin)
Methenamine Silver
METHENAMINE (MART.)
METHENAMINE [MART.]
METHENAMINE (USP-RS)
METHENAMINE [USP-RS]
S 4
1,3,5,7-Tetraazatricyclo[3.3.1.1(3,7)]decane
1,3,5,7-tetraazatricyclo[3.3.1.1^{3,7}]decane
METHENAMINE (EP MONOGRAPH)
METHENAMINE [EP MONOGRAPH]
METHENAMINE (USP MONOGRAPH)
METHENAMINE [USP MONOGRAPH]
1,3,5,7-TETRAAZATRICYCLO(3.3.1.1 SUP(3,7))DECANE
Methenamine [USAN:INN]
1,3,5,7-Tetraazatricyclo(3.3.1.13,7)decane hydroiodide
CAS-100-97-0
Esametilentetramina [Italian]
Hexamethylentetramin [German]
SMR000857139
hexamethylene-tetramine
NSC403347
SR-05000002024
1,3,5,7-Tetraazatricyclo(3.3.1.1(3,7))decane
1,3,5,7-Tetraazatricyclo[3.3.1.1{3,7}]decane
UN1328
1,3,5,7-Tetraazatricyclo[3.3.1.1(sup 3,7)]decane
metheneamine
Hexamethylamine
Naphthamine
Methamine
Urasal
Carin
HEXAMETHYLENETETRAMINE, ACS
Prestwick_79
Vulkacit H30
1,3,5,7-Tetraazatricyclo[3.3.1.13,7 ]decane
Grasselerator 102
Cystex (Salt/Mix)
hexam-ethylenetetraamine
hexamethylene tetraamine
Spectrum_000991
METHENAMINE [MI]
Spectrum2_000827
Spectrum3_001730
Spectrum4_000872
Spectrum5_001603
Methenamine (Mandelamine)
METHENAMINE [INN]
Formaldehyde-ammonia 6:4
[16]-Adamazane, INN
component of Uro-Phosphate
METHENAMINE [HSDB]
METHENAMINE [INCI]
Uro-phosphate (Salt/Mix)
1,5,7-Tetraazaadamantane
Hexamethylentetramin(german)
METHENAMINE [VANDF]
Hexamethylenetetramine, 8CI
1,3,5,7-tetraazatricyclo[3.3.1.1?,?]decane
SCHEMBL33785
BSPBio_003380
Hexamethylenetetramine, tech.
KBioGR_001563
KBioSS_001471
METHENAMINE [WHO-DD]
Hexamethylenetetramine [UN1328] [Flammable solid]
MLS001332361
MLS001332362
MLS002207085
DivK1c_000322
SPECTRUM1500394
SPBio_000753
Hexamethylenetetramine, BioXtra
CHEMBL1201270
GTPL10913
HMS501A04
KBio1_000322
KBio2_001471
KBio2_004039
KBio2_006607
KBio3_002600
J01XX05
NINDS_000322
HMS1920L13
HMS2091D08
HMS2233B09
HMS3371O15
HMS3652A05
HMS3715D17
Pharmakon1600-01500394
HY-B0514
STR00289
Tox21_113455
Tox21_201606
Tox21_300502
CCG-40289
Hexamethylenetetramine, LR, >=99%
NSC757101
s3139
STL197471
AKOS000120003
AKOS005169648
Tox21_113455_1
Urotropine 100 microg/mL in Methanol
DB06799
NSC-757101
IDI1_000322
NCGC00094719-01
NCGC00094719-02
NCGC00094719-03
NCGC00094719-05
NCGC00094719-06
NCGC00094719-08
NCGC00254463-01
NCGC00259155-01
SBI-0051439.P003
FT-0627024
FT-0669190
H0093
Hexamethylenetetramine, ReagentPlus(R), 99%
SW199604-2
EN300-16855
1,5,7-Tetraazatricyclo[3.3.1.13,7]decane
D00393
Hexamethylenetetramine, ACS reagent, >=99.0%
Q71969
AB00052038_08
AB00052038_09
1,3,5,7-tetraaza-tricyclo[3.3.1.13,7]decane
1,3,5,7-tetraazatricyclo-[3.3.1.13,7]decane
1,3,5,7-tetraazatricyclo[3,3,1,13,7]decane
1,3,5,7-tetraazatricyclo[3.3.1.1,3,7]decane
AE-641/00560026
WLN: T66 B6 A B-C 1B I BN DN FN HNTJ
Hexamethylenetetramine [UN1328] [Flammable solid]
Hexamethylenetetramine, analytical reference material
Hexamethylenetetramine, p.a., ACS reagent, 99.0%
Hexamethylenetetramine, SAJ first grade, >=98.5%
J-000293
J-521456
SR-05000002024-1
SR-05000002024-3
1,3,5,7-tetraaza-tricyclo[3.3.1.1*3,7*]decane
1,3,5,7-Tetraazatricyclo-[3.3.1.1(3,7)]decane
BRD-K30114692-001-10-0
Hexamethylenetetramine, JIS special grade, >=99.0%
F2173-0429
Z362014242
Methenamine, European Pharmacopoeia (EP) Reference Standard
Methenamine, United States Pharmacopeia (USP) Reference Standard
InChI=1/C6H12N4/c1-7-2-9-4-8(1)5-10(3-7)6-9/h1-6H
Hexamethylenetetramine, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99.0%


HEXAMETHYLENETETRAMINE
Hexamethylenetetramine is a white crystalline heterocyclic organic compound
Hexamethylenetetramine is highly soluble in water and polar organic solvents.
Hexamethylenetetramine's chemical formula is (CH2)6N4.


CAS NUMBER: 100-97-0

EC NUMBER: 202-905-8

MOLECULAR FORMULA: C6H12N4

MOLECULAR WEIGHT: 140.19 g/mol

IUPAC NAME: 1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane



Hexamethylenetetramine is also known as methenamine, hexamine, or urotropin
Hexamethylenetetramine is a heterocyclic organic compound

Hexamethylenetetramine's molecular formula is (CH2)6N4.
This white crystalline compound is highly soluble in water and polar organic solvents.

Hexamethylenetetramine has a cage-like structure similar to adamantane.
Hexamethylenetetramine is useful in the synthesis of other organic compounds, including plastics, pharmaceuticals, and rubber additives.

Hexamethylenetetramine sublimes in vacuum at 280 °C.
Hexamethylenetetramine is also known as methenamine

The flammable solid has a cage-like structure similar to adamantine.
Hexamethylenetetramine is used in the synthesis of other chemical compounds such as plastics, pharmaceuticals, and rubber additives.

Hexamethylenetetramine appears as odorless white crystalline powder or colorless lustrous crystals.
Hexamethylenetetramine sublimes in a vacuum at about 505 °F with some decomposition

Hexamethylenetetramine is a polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.
Hexamethylenetetramine has a role as an antibacterial drug.

Hexamethylenetetramine is a polycyclic cage, a polyazaalkane and a tetramine.
Hexamethylenetetramine is a heterocyclic organic compound with a cage-like structure similar to adamantane.
In salt form Hexamethylenetetramine is used for the treatment of urinary tract infection


APPLICATIONS:
The dominant use of hexamethylenetetramine is in the production of powdery or liquid preparations of phenolic resins and phenolic resin moulding compounds, where it is added as a hardening component.
These products are used as binders, e.g. in brake and clutch linings, abrasive products, non-woven textiles, formed parts produced by moulding processes, and fireproof materials.

Medical Uses:
As the mandelic acid salt (methenamine mandelate) or the hippuric acid salt (methenamine hippurate), it is used for the treatment of urinary tract infection.
In an acidic environment, methenamine is believed to act as an antimicrobial by converting to formaldehyde.
A systematic review of its use for this purpose in adult women found there was insufficient evidence of benefit and further research is needed.
As Hexamethylenetetramine is an antiseptic, it may avoid the issue of antibiotic resistance.
Hexamethylenetetramine acts as an over-the-counter antiperspirant due to the astringent property of formaldehyde.

Histological Stains:
Hexamethylenetetramine silver stains are used for staining in histology, including the following types:
Hexamethylenetetramine widely used as a screen for fungal organisms.

Solid Fuel:
Together with 1,3,5-trioxane, hexamethylenetetramine is a component of hexamine fuel tablets used by campers, hobbyists, the military and relief organizations for heating camping food or military rations.
Hexamethylenetetramine burns smokelessly
Hexamethylenetetramine has a high energy density of 30.0 megajoules per kilogram (MJ/kg)

Food Additive:
Hexamethylenetetramine or hexamine is also used as a food additive as a preservative
Hexamethylenetetramine is approved for usage for this purpose in the EU, where it is listed under E number E239, however it is not approved in the USA, Russia, Australia, or New Zealand.

Reagent in Organic Chemistry:
Hexamethylenetetramine is a versatile reagent in organic synthesis.
Hexamethylenetetramine is used in the Duff reaction (formylation of arenes), the Sommelet reaction (converting benzyl halides to aldehydes), and in the Delepine reaction (synthesis of amines from alkyl halides).

Historical Uses:
Hexamethylenetetramine was first introduced into the medical setting in 1895 as a urinary antiseptic.
However, Hexamethylenetetramine was only used in cases of acidic urine, whereas boric acid was used to treat urinary tract infections with alkaline urine.
Scientist De Eds found that there was a direct correlation between the acidity of hexamethylenetetramine's environment and the rate of its decomposition.
Therefore, its effectiveness as a drug depended greatly on the acidity of the urine rather than the amount of the drug administered.
In an alkaline environment, hexamethylenetetramine was found to be almost completely inactive.

Hexamethylenetetramine's CAS Number is 100-97-0
Hexamethylenetetramine is an odorless, white crystalline powder or colorless lustrous crystal.

The flammable solid heterocyclic organic compound sublimes in a vacuum at about 505° F with some decomposition.
Hexamethylenetetramine is prepared by combining formaldehyde and ammonia.
The reaction can be conducted in gas phase and in solution.

Industry Uses:
Hexamethylenetetramine is dominantly used in the production of powdery or liquid preparations of phenolic resins and phenolic resin molding compounds where it is added as a hardening component.
These products are used as binders in the manufacture of brake and clutch linings, abrasive products, non-woven textiles, formed parts produced by molding processes, and fireproof materials.
Hexamethylenetetramine is also used in the medical profession for the treatment of urinary tract infections.


PHYSICAL PROPERTIES:

-Molecular Weight: 140.19 g/mol

-XLogP3-AA: 0.3

-Exact Mass: 140.106196400 g/mol

-Monoisotopic Mass: 140.106196400 g/mol

-Topological Polar Surface Area: 13Ų

-Physical Description: odorless white crystalline powder or colorless lustrous crystals

-Color: Colorless

-Form: Solid

-Odor: Odorless

-Boiling Point: Sublimes

-Melting Point: 536 °F

-Flash Point: 250 °C

-Solubility: 302,300 mg/L

-Density: 1.35

-Vapor Density: 4.9

-Vapor Pressure: 0.004 mmHg

-Autoignition Temperature: 390 °C

-Refractive Index: 1.5911

The crystalline compound is also used as a reagent in organic chemistry
Hexamethylenetetramine is used as a food additive

Hexamethylenetetramine can be used as a preservative
Hexamethylenetetramine also used as the base component in the manufacture of certain explosives.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 0

-Hydrogen Bond Acceptor Count: 4

-Rotatable Bond Count: 0

-Heavy Atom Count: 10

-Formal Charge: 0

-Complexity: 84.8

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic


Consumer Uses
-Adhesives and Sealants
-Agricultural Products (non-pesticidal)
-Automotive Care Products
-Building/Construction Materials not covered elsewhere
-CBI
-Plastic and Rubber Products not covered elsewhere

Hexamethylenetetramine is a polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.
Hexamethylenetetramine, also known as methenamine, hexamine, or urotropin, is a heterocyclic organic compound with the formula (CH2)6N4.

This white crystalline compound is highly soluble in water and polar organic solvents.
Hexamethylenetetramine has a cage-like structure similar to adamantane.

Hexamethylenetetramine is useful in the synthesis of other organic compounds, including plastics, pharmaceuticals, and rubber additives.
Hexamethylenetetramine sublimes in vacuum at 280 °C.

Hexamethylenetetramine is used especially as an accelerator in vulcanizing rubber and as a urinary antiseptic
Hexamethylenetetramine is also called Methenamine, Hexamethylenetetramine or Urotropin.

Hexamethylenetetramine acts as an anti-infective agent which is most commonly used to treat urinary tract infections.
Hexamethylenetetramine's anti-infective action is derived from the slow release of formaldehyde (CH2O) by hydrolysis at acidic pH of 0.2 molars.
Hexamethylenetetramine is an odourless colourless lustrous crystal or white crystalline powder which is hygroscopic.

USES:
Hexamethylenetetramine is used in the production of liquid or powdery preparations of phenolic resins.
Hexamethylenetetramine is used as binders in clutch and brake linings.

Hexamethylenetetramine is used in the form of spray and cream to treat concomitant odour and excessive sweating.
Hexamethylenetetramine is used in Grocott's methenamine silver stain.

Hexamethylenetetramine is used as a solid fuel.
Hexamethylenetetramine is used as a food preservative.

Hexamethylenetetramine is used as a primary ingredient in making RDX.
Hexamethylenetetramine is used to prevent vulcanized rubber.
Hexamethylenetetramine is used as a corrosion inhibitor for steel.

Hexamethylenetetramine is odorless white crystalline powder or colorless lustrous crystals.
Hexamethylenetetramine sublimes in a vacuum at about 505°F with some decomposition.

Hexamethylenetetramine's solutions are strong bases
Hexamethylenetetramine is a tetraamine compound with a structure analogous to adamantane.

Hexamethylenetetramine is used in synthesis as a formylation agent and is employed in preparing specialized materials.
Hexamethylenetetramine is found in antibiotics, solid fuel tablets used for cooking while camping or hiking, rubber/textile adhesives, paints, lacquers, photography products, and in the production of deodorants and hair products.

Hexamethylenetetramine is used as a preservative in cheeses, in test carpets for fire-protection, and as a hardening component to binders such as brake and clutch linings, abrasive products, nonwoven textiles, and fireproof materials
Hexamethylenetetramine is a white crystalline diamond - hygroscopic crystalline powder or colorless, shiny, flammable.

Melting point is 263℃, if more than the melting point, it will be sublimation and decomposition, but not melting.
Hexamethylenetetramine has a symmetric tetrahedral cage-like structure, similar to adamantane, whose four "corners" are nitrogen atoms and "edges" are methylene bridges.

Although the molecular shape defines a cage, no void space is available at the interior for binding other atoms or molecules, unlike crown ethers or larger cryptand structures.
The molecule behaves like an amine base, undergoing protonation and N-alkylation.

Hexamethylenetetramine is a heterocyclic organic compound that has the chemical formula C6H12N4.
Hexamethylenetetramine is also known as Hexamethylenetetramine, Methenamine, or Urotropin.

Hexamethylenetetramine acts as an anti-infective agent, the most commonly used element to treat urinary tract infections. 
Industrially, Hexamethylenetetramine is prepared by the combination of ammonia and formaldehyde and the reaction can be conducted in a gas phase and solution.

The molecule contains a symmetric tetrahedral cage-like structure, similar to adamantane, whose "edges" are methylene bridges, and the four "corners" are nitrogen atoms.
This compound acts as an anti-infective agent, which is the most commonly used element to treat urinary tract infections.

The anti-infective action of Hexamethylenetetramine is derived from the slow release of formaldehyde (CH2O) by the process of hydrolysis at an acidic pH of 0.2 molars.
Also, Hexamethylenetetramine is a colorless, odorless, and lustrous crystal or white hygroscopic crystalline powder.

GENERAL PROPERTIES:

*The chemical formula for hexamine can be given as C6H12N4,

*The density of Hexamine is 1.33 g/cm3,

*The molecular weight of C6H12N4 is 140.186 g/mol,

*The Boiling point of Hexamine can be given as "Sublimes,"

*The Melting point of Hexamine can be given as 280°C,

*The odor of this compound is Fishy (Ammonia like).


SYNONYMS:

methenamine
Hexamethylenetetramine
100-97-0
Hexamine
Urotropine
Aminoform
Urotropin
Hexamethylenamine
1,3,5,7-Tetraazaadamantane
HMTA
Hexamethylene tetramine
Methenamin
Uritone
Hexamethylenetetraamine
Formamine
Aminoformaldehyde
Ammoform
Ammonioformaldehyde
Antihydral
Cystamin
Cystogen
Duirexol
Hexaform
Metramine
Resotropin
Uratrine
Urodeine
Xametrin
Formin
Heterin
Uramin
Preparation AF
Hexamethyleneamine
Hexilmethylenamine
Hexa-Flo-Pulver
Ekagom H
methenaminum
Hexaloids
Hexaminum
Metenamina
Aceto HMT
Herax UTS
Hexasan
Hexamethylentetramin
Nocceler H
Sanceler H
Formin (heterocycle)
Hexamine (heterocycle)
Vulkacit H 30
Hexamethylentetraminum
Hexamethylentetramine
S 4 (heterocycle)
Hexamethylenetetraminum
Esametilentetramina
Silver Methenamine
Hexasan (VAN)
Methamin
1,3,5,7-Tetraazatricyclo[3.3.1.13,7]decane
Caswell No. 482
Hexamine Silver
Uro-phosphate
Sanceler HT
Heksa K
Hexamine Superfine
Methenamine Silver
Nocceler H-PO
Sanceler HT-PO
Hexa B
1,3,5,7-tetraazatricyclo[3.3.1.1~3,7~]decane
Cohedur H 30
Rhenogran HEXA 80
Thixon 715B
Metenamine
1,3,5,7-Tetraazatricyclo (3.3.1.1(3,7))decane
CCRIS 2297
HSDB 563
Vesaloin
Urisol
HMT
Methenamine
Metenamina
Methenaminum
UNII-J50OIX95QV
EINECS 202-905-8
J50OIX95QV
NSC 26346
NSC-26346
Hexamine (JAN)
Hexamine (TN)
Esametilentetramina
Hexamethylentetramin
CHEBI:6824
INS NO.239
1,3,5,7-Tetraazatricyclo(3.3.1.13,7)decane
DTXSID6020692
hexamethylene-tetramine
AI3-09611
C6H12N4
Hexamethylenetetramine (aliphatic)
INS-239
1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 37))decane
UN1328
NSC-403347
DTXCID00692
H.M.T.
E-239
EC 202-905-8
1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane
Formin (the heterocyclic compound)
NSC26346
MFCD00006895
1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 3,7))decane
NCGC00094719-04
E239
Hexamethylenetetramine
S 4
1,3,5,7-Tetraazatricyclo[3.3.1.1(3,7)]decane
1,3,5,7-tetraazatricyclo[3.3.1.1^{3,7}]decane
METHENAMINE (EP MONOGRAPH)
METHENAMINE [EP MONOGRAPH]
METHENAMINE (USP MONOGRAPH)
METHENAMINE [USP MONOGRAPH]
1,3,5,7-TETRAAZATRICYCLO(3.3.1.1 SUP(3,7))DECANE
C6H12N4.xHI
C6-H12-N4.x-H-I
1,3,5,7-Tetraazatricyclo(3.3.1.13,7)decane hydroiodide
CAS-100-97-0
SMR000857139
NSC403347
1,3,5,7-Tetraazotricyclo[3.3.1.13,7]decane
SR-05000002024
1,3,5,7-Tetraazatricyclo(3.3.1.1(3,7))decane
1,3,5,7-Tetraazatricyclo[3.3.1.1{3,7}]decane
1,3,5,7-Tetraazatricyclo[3.3.1.1(sup 3,7)]decane
metheneamine
Hexamethylamine
Naphthamine
Methamine
Urasal
Carin
Hexamthylnettramine
HEXAMETHYLENETETRAMINE, ACS
Heksametylentetramin
Hexametilentetramina
Prestwick_79
1,3,5,7-tetraazatricyclo[3.3.1.13,7]decane hydroiodide
Vulkacit H30
1,3,5,7-Tetraazatricyclo[3.3.1.13,7 ]decane
Grasselerator 102
1,3,5,7-Tetraazatricyclo(3.3.1.1(3,7)-)decane, hydriodide
Cystex (Salt/Mix)
hexam-ethylenetetraamine
hexamethylene tetraamine
Spectrum_000991
HMT (CHRIS Code)
METHENAMINE [MI]
1357-Tetraazaadamantane
Spectrum2_000827
Spectrum3_001730
Spectrum4_000872
Spectrum5_001603
Methenamine (Mandelamine)
METHENAMINE [INN]
Formaldehyde-ammonia 6:4
[16]-Adamazane, INN
component of Uro-Phosphate
METHENAMINE
Uro-phosphate (Salt/Mix)
1,5,7-Tetraazaadamantane
D02LJR
METHENAMINE [VANDF]
Hexamethylenetetramine, 8CI
1,3,5,7-tetraazatricyclo[3.3.1.1?,?]decane
SCHEMBL33785
BSPBio_003380
Hexamethylenetetramine (8CI)
Hexamethylenetetramine, tech.
KBioGR_001563
KBioSS_001471
METHENAMINE [WHO-DD]
MLS001332361
MLS001332362
MLS002207085
DivK1c_000322
Hexamethylenetetramine (HMTA)
SPECTRUM1500394
SPBio_000753
Hexamethylenetetramine, BioXtra
CHEMBL1201270
GTPL10913
HMS501A04
J01XX05
NINDS_000322
HMS1920L13
HMS2091D08
HMS2233B09
HMS3371O15
HMS3652A05
HMS3715D17
Pharmakon1600-01500394
HY-B0514
STR00289
CCG-40289
Hexamethylenetetramine, LR, >=99%
LS-313
NA1328
NSC757101
s3139
STL197471
AKOS000120003
AKOS005169648
Hexamethylenetetraamine; (Methenamine)
Tox21_113455_1
Urotropine 100 microg/mL in Methanol
DB06799
NSC-757101
IDI1_000322
NCGC00094719-01
NCGC00094719-02
NCGC00094719-03
NCGC00094719-05
NCGC00094719-06
NCGC00094719-08
NCGC00254463-01
NCGC00259155-01
SBI-0051439.P003
FT-0627024
FT-0669190
H0093
Hexamethylenetetramine, ReagentPlus(R), 99%
SW199604-2
EN300-16855
1,5,7-Tetraazatricyclo[3.3.1.13,7]decane
D00393
Q71969
AB00052038_08
AB00052038_09
1,3,5,7-tetraaza-tricyclo[3.3.1.13,7]decane
1,3,5,7-tetraazatricyclo-[3.3.1.13,7]decane
1,3,5,7-tetraazatricyclo[3,3,1,13,7]decane
1,3,5,7-tetraazatricyclo[3.3.1.1,3,7]decane
1,5:3,7-Dimethano-1,3,5,7-tetraazacyclooctane
AE-641/00560026
WLN: T66 B6 A B-C 1B I BN DN FN HNTJ
1,3,5,7-Tetraazatriciclo [3.3.1.13,7] decano
1,3,5,7-Tetraazatricyclo-nu[3.3.1.13,7]decane
1,3,5,7-Tetraazatricyclo[3.3.1.13#,7]decane
Hexamethylenetetramine [UN1328] [Flammable solid]
Hexamethylenetetramine
J-000293
J-521456
SR-05000002024-1
SR-05000002024-3
1,3,5,7-tetraaza-tricyclo[3.3.1.1*3,7*]decane
1,3,5,7-Tetraazatricyclo-[3.3.1.1(3,7)]decane
BRD-K30114692-001-10-0
Hexamethylenetetramine
F2173-0429
Z362014242
Methenamine
1 3 5 7-Tetraazatricyclo[3.3.1.13 7]decane (Urotropine)
Hexamethylenetetramine
Hexamethylenetetramine
Hexamine, Formin, Urotropin; 1,3,5,7- Tetraazaadamantane; Ammonioformaldehyde; Aceto HMT; Aminoform; Ammoform; Cystamin; Cystogen; Formamine; Hexaform; Hexamethylenamine; Urotropin; Hexilmethylenamine; HMT; CAS NO:100-97-0
HEXAMIDINE DIISETHIONATE
HEXAMIDINE DIISETHIONATE CAS Number: 659-40-5 Hexamidine Diisethionate What Is Hexamidine Diisethionate? In cosmetics and personal-care products, Hexamidine and Hexamidine Diisethionate function as a preservatives and are used in the formulation of hair, nail, and skin-care products, as well as eye makeup and baby products. Why is Hexamidine Diisethionate used in cosmetics and personal care products? Hexamidine Diisethionate helps cleanse the skin or prevent odor by destroying or inhibiting the growth of microorganisms. Scientific Facts: Hexamidine Diisethionate is an organic salt of Hexamidine. Hexamidine is soluble in water and insoluble in organic solvents. These ingredients function as preservatives, which help cleanse the skin or prevent odor by inhibiting the growth of or destroying microorganisms, such as bacteria, fungi and yeast. HEXAMIDINE DIISETHIONATE HEXAMIDINE DIISETHIONATE is classified as : Antifoaming Emollient Preservative Skin conditioning CAS Number 659-40-5 EINECS/ELINCS No: 211-533-5 Restriction (applies to EU only): VI/47 COSING REF No: 34260 Chem/IUPAC Name: 2-Hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1) Hexamidine Hexamidine Skeletal formula of hexamidine Ball-and-stick model Names IUPAC name 4,4'-[hexane-1,6-diylbis(oxy)]dibenzenecarboximidamide Other names 4-[6-(4-carbamimidoylphenoxy)hexoxy]benzamidine Identifiers CAS Number 3811-75-4 check 3D model (JSmol) Interactive image ChEBI CHEBI:87184 ☒ ChEMBL ChEMBL25105 check ChemSpider 58639 check DrugBank DB03808 check PubChem CID 65130 UNII 3483C2H13H check CompTox Dashboard (EPA) DTXSID60191524 InChI[show] SMILES[show] Properties Chemical formula C20H26N4O2 Molar mass 354.446 Pharmacology ATC code D08AC04 (WHO) R01AX07 (WHO) R02AA18 (WHO) S01AX08 (WHO) S03AA05 (WHO) Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ☒ verify (what is check☒ ?) Infobox references Hexamidine is an antiseptic and disinfectant. Hexomedine is the trade name of a diisethionate solution (1/1.000) of hexamidine.[1] Hexamidine is used primarily as its diisethionate salt, which is more water-soluble than the dihydrochloride. The dihydrochloride was first synthesized and patented as a trypanocide for May & Baker in 1939. Its amoebicidal properties emerged in the 1990s. The exact mechanism of its biocidal action is unknown, but presumed similar to quaternary ammonium compounds, involving binding to the negatively charged lipid membranes of pathogens. Hexamidine and its shorter congener, propamidine, are used as antiseptics and preservatives in pharmaceuticals and cosmetics. They are particularly used for the topical treatment of acanthamoebiasis (Acanthamoeba keratitis) Molecular Weight of Hexamidine Diisethionate 606.7 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Hydrogen Bond Donor Countt of Hexamidine Diisethionate 8 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Hydrogen Bond Acceptor Countt of Hexamidine Diisethionate 12 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Rotatable Bond Countt of Hexamidine Diisethionate 15 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Exact Masst of Hexamidine Diisethionate 606.202936 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Monoisotopic Masst of Hexamidine Diisethionate 606.202936 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Topological Polar Surface Areat of Hexamidine Diisethionate 284 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Heavy Atom Countt of Hexamidine Diisethionate 40 Computed by PubChem Formal Charget of Hexamidine Diisethionate 0 Computed by PubChem Complexityt of Hexamidine Diisethionate 505 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Isotope Atom Countt of Hexamidine Diisethionate 0 Computed by PubChem Defined Atom Stereocenter Countt of Hexamidine Diisethionate 0 Computed by PubChem Undefined Atom Stereocenter Countt of Hexamidine Diisethionate 0 Computed by PubChem Defined Bond Stereocenter Countt of Hexamidine Diisethionate 0 Computed by PubChem Undefined Bond Stereocenter Countt of Hexamidine Diisethionate 0 Computed by PubChem Covalently-Bonded Unit Countt of Hexamidine Diisethionate 3 Computed by PubChem Compound of Hexamidine Diisethionate is Canonicalized Yes CAS number: 659-40-5 "Satisfactory" in all categories. Origin (s): Synthetic INCI name: HEXAMIDINE DIISETHIONATE EINECS / ELINCS number: 211-533-5 Classification: Regulated, Conservative Restriction in Europe: The maximum authorized concentration in ready-to-use cosmetic preparations is 0.1%. Its functions (INCI) Anti-foaming: Suppresses foam during manufacturing / reduces foaming in liquid end products Emollient: Softens and softens the skin Preservative: Inhibits the development of microorganisms in cosmetic products. Skin care agent: Keeps the skin in good condition Anti-Dandruff: Helps fight dandruff Antimicrobial: Helps slow the growth of microorganisms on the skin and inhibits the growth of microbes This ingredient is present in 0.06% of cosmetics. HEXAMIDINE (DIISETHIONATE) Each drug has one or more active principle (s) which gives it (s) a particular therapeutic effect. An active principle can be a set of chemical compounds or a natural plant, mineral or animal substance. Find in this section a medicine according to its active principle, also called active substance. Hexamidine can cause contact dermatitis. It is considered non-toxic in cosmetics for concentrations of 0.03% to 0.1%. HEXAMIDINE: MECHANISM OF ACTION Hexamidine (belonging to the family of diamidines) is a cationic antibacterial agent and exhibits surfactant properties. In vitro, its activity is exerted on Gram + bacteria and is not inhibited by pus, serum or organic debris. HEXAMIDINE: USE CASE Ophthalmically, hexamidine is used in the management of: bacterial blepharitis, bacterial conjunctivitis, dacryocystitis, bacterial keratoconjunctivitis. By the nasal route, hexamidine is used in the management of acute nasopharyngitis. Dermally, hexamidine is used in the management of bacterial skin conditions. By the ear, in combination with lidocaine, hexamidine is used in the management of otitis externa. By local route, in combination with lidocaine or tetracaine, hexamidine is used in the management of oral disorders.
HEXAMINE
CAS Number: 100-97-0
EC Number: 202-905-8
Formula:C6H12N4
Preferred IUPAC name: 1,3,5,7-Tetraazaadamantane
Substance name:Hexamethylenetetramine
Trade name:Hexamine
DESCRIPTION:

Hexamethylenetetramine, also known as methenamine, hexamine, or urotropin, is a heterocyclic organic compound with the formula (CH2)6N4.
Hexamine is highly soluble in water and polar organic solvents.
Hexamine has a cage-like structure similar to adamantane.
Hexamine is useful in the synthesis of other organic compounds, including plastics, pharmaceuticals, and rubber additives.
Hexamine sublimes in vacuum at 280 °C.
Hexamine also called methenamine, Hexamine is a white crystalline solid.
Hexamine is moderately soluble in water and is very soluble in most organic solvents.
Hexamine is a heterocyclic organic compound that can be prepared by a reaction of formaldehyde and ammonia.

C6H12N4 is a heterocyclic organic compound with the chemical name Hexamine.
It is also called Methenamine, Hexamethylenetetramine or Urotropin.

Hexamine acts as an anti-infective agent which is most commonly used to treat urinary tract infections.
Its anti-infective action is derived from the slow release of formaldehyde (CH2O) by hydrolysis at acidic pH of 0.2 molars.
Hexamine is an odourless colourless lustrous crystal or white crystalline powder which is hygroscopic.
Hexamine is a urinary tract antiseptic that is used as suppressive therapy for chronic or recurrent urinary tract infections.
Hexamine has not been linked to serum enzyme elevations or to instances of clinically apparent acute liver injury.
Hexamine is a heterocyclic organic compound with antibiotic activity.
In the body methenamine is converted to formaldehyde, a nonspecific bactericidal agent. Hexamine is typically used long-term to treat chronic urinary tract infections and to prevent the recurrence of infections.
Hexamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).





SYNTHESIS, STRUCTURE, REACTIVITY OF HEXAMINE:
Hexamine was discovered by Aleksandr Butlerov in 1859.
Hexamine is prepared industrially by combining formaldehyde and ammonia:
The reaction can be conducted in gas phase and in solution.
The molecule has a tetrahedral cage-like structure, similar to adamantane.
Four vertices are occupied by nitrogen atoms, which are linked by methylene groups.
Although the molecular shape defines a cage, no void space is available at the interior for binding other atoms or molecules, unlike crown ethers or larger cryptand structures.
The molecule behaves like an amine base, undergoing protonation and N-alkylation (e.g. quaternium-15).













APPLICATIONS OF HEXAMINE:
The dominant use of hexamethylenetetramine is in the production of powdery or liquid preparations of phenolic resins and phenolic resin moulding compounds, where it is added as a hardening component.
These products are used as binders, e.g. in brake and clutch linings, abrasive products, non-woven textiles, formed parts produced by moulding processes, and fireproof materials.
As an antibiotic, solid food tablet for cooking, in the production of other compounds, in rubber and textile adhesives, paints, lacquers, in the production of explosives, and as a corrosion inhibitor.
Hexamine is used in the production of liquid or powdery preparations of phenolic resins.
Hexamine is Used as binders in clutch and brake linings.
Hexamine is Used in the form of spray and cream to treat concomitant odour and excessive sweating.
Hexamine is Used in Grocott’s methenamine silver stain.
Hexamine is Used as a solid fuel.
Hexamine is Used as a food preservative.
Hexamine is Used as a primary ingredient in making RDX.
Hexamine is Used to prevent vulcanized rubber.
Hexamine is Used as a corrosion inhibitor for steel.

One of the major uses of Hexamine is in the manufacture of dinitrosopentamethylene-tetramine, a blowing agent for rubber.
Hexamine is used as a catalyst in the manufacture of Bakelite phenol formaldehyde molding powders.
Hexamine is used as a basic raw material in slurry explosives.
Hexamine has many other applications in the manufacture of plastics, paints, foundry resins, textiles, plywood, laminated sheets, cement, fertilizers, pesticides, solid fuel tablets etc.
Unstabilized Hexamine is used in adhesives, coatings and sealing compounds, in the preservation of hides, as cross-linking agent for hardening phenol-formaldehyde resins and vulcanizing rubber, as corrosion inhibitor for steel, as dye fixative, as fuel tablets for camping stoves, as stabilizer for lubricating and insulating oils, for manufacture of explosives, chemical detection of metals and as an urinary antiseptic.
Stabilized Hexamine is used in process industry, as per the requirements of specific customers.
Hexamethylenetetramine is prepared industrially by reacting formaldehyde and ammonia.

The reaction can be conducted in gas phase and in solution.

MAJOR APPLICATIONS:
• Curing agent for industrial phenolic resins (Novolac Resins)
• Rubber and lacquer film as cross-linking or vulcanizing agent
• Plastics industry
• Mining explosives
• Medicine and food industry
• Analytical chemistry
• As dry fuel - Fuel tablets
• Chemical intermediate/chemical synthesis
• Antiseptic agent for livestock
• Preservative & anti-microbial effect
• Corrosion inhibitor
• Foam manufacturing
• Synthetic resin industry
• Pharmaceuticals industry
• Photographic industry
• Metal industry
• Lubricant industry



Medical uses:
As the mandelic acid salt (methenamine mandelate) or the hippuric acid salt (methenamine hippurate), it is used for the treatment of urinary tract infection.
In an acidic environment, methenamine is believed to act as an antimicrobial by converting to formaldehyde.
A systematic review of its use for this purpose in adult women found there was insufficient evidence of benefit and further research is needed.
Methenamine acts as an over-the-counter antiperspirant due to the astringent property of formaldehyde.

Histological stains:
Methenamine silver stains are used for staining in histology, including the following types:
Grocott's methenamine silver stain, used widely as a screen for fungal organisms.
Jones' stain, a methenamine silver-Periodic acid-Schiff that stains for basement membrane, availing to view the "spiked" Glomerular basement membrane associated with membranous glomerulonephritis.
Solid fuel:
Together with 1,3,5-trioxane, hexamethylenetetramine is a component of hexamine fuel tablets used by campers, hobbyists, the military and relief organizations for heating camping food or military rations.
It burns smokelessly, has a high energy density of 30.0 megajoules per kilogram (MJ/kg), does not liquify while burning, and leaves no ashes, although its fumes are toxic.

Standardized 0.149 g tablets of methenamine (hexamine) are used by fire-protection laboratories as a clean and reproducible fire source to test the flammability of carpets and rugs.

Food additive:
Hexamethylene tetramine or hexamine is also used as a food additive as a preservative (INS number 239).
It is approved for usage for this purpose in the EU, where it is listed under E number E239, however it is not approved in the USA, Russia, Australia, or New Zealand.

Reagent in organic chemistry:
Hexamethylenetetramine is a versatile reagent in organic synthesis.
It is used in the Duff reaction (formylation of arenes), the Sommelet reaction (converting benzyl halides to aldehydes), and in the Delepine reaction (synthesis of amines from alkyl halides).

Explosives:
Hexamethylenetetramine is the base component to produce RDX and, consequently, C-4 as well as Octogen, hexamine dinitrate, hexamine diperchlorate and HMTD.

Historical uses:
Hexamethylenetetramine was first introduced into the medical setting in 1895 as a urinary antiseptic.
However, it was only used in cases of acidic urine, whereas boric acid was used to treat urinary tract infections with alkaline urine.
Scientist De Eds found that there was a direct correlation between the acidity of hexamethylenetetramine's environment and the rate of its decomposition.
Therefore, its effectiveness as a drug depended greatly on the acidity of the urine rather than the amount of the drug administered.
In an alkaline environment, hexamethylenetetramine was found to be almost completely inactive.

Hexamethylenetetramine was also used as a method of treatment for soldiers exposed to phosgene in World War I.
Subsequent studies have shown that large doses of hexamethylenetetramine provide some protection if taken before phosgene exposure but none if taken afterwards.




CHEMICAL AND PHYSICAL PROPERTIES OF HEXAMINE:
Chemical formula: C6H12N4
Molar mass: 140.186 g/mol
Appearance: White crystalline solid
Odor: Fishy, ammonia like
Density: 1.33 g/cm3 (at 20 °C)
Melting point: 280 °C (536 °F; 553 K) (sublimes)
Solubility in water: 85.3 g/100 mL
Solubility: Soluble in chloroform, methanol, ethanol, acetone, benzene, xylene, ether
Solubility in chloroform: 13.4 g/100 g (20 °C)
Solubility in methanol: 7.25 g/100 g (20 °C)
Solubility in ethanol: 2.89 g/100 g (20 °C)
Solubility in acetone: 0.65 g/100 g (20 °C)
Solubility in benzene: 0.23 g/100 g (20 °C)
Acidity (pKa): 4.89
Flash point: 250 °C (482 °F; 523 K)
Autoignition temperature: 410 °C (770 °F; 683 K)
CAS Number: 100 – 97 – 0
EINECS Number: 202 – 905 – 8
Chemical Name :Hexamethylene tetramine
Chemical Classification: Amine / Cyclic amine
Formula: C6H12N4
Molecular weight. 140.19
Shipping Name: Hexamine
Codes / Label: Flammable solid, class – 4.1
UN Number: 1328
Description: White crystalline odorless solid.
Molecular Weight: 140.19
XLogP3-AA: 0.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 140.106196400
Monoisotopic Mass: 140.106196400
Topological Polar Surface Area: 13 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 84.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Product Standard:
Appearance: White crystals
Purity (%): No less than 99.5
Water Content (%): 0.5 or less
PH(PH): No less than 7.5
Color Number (APHA): 10 or less
Ash Content (%): 0.01 or less
Ammonium Salt (%): 0.001 or less
Sulfate(SO4)(%): 0.02
Chloride(Cl)(%): 0.015
Heavy Metal(Pb)(%): 0.001


SAFETY INFORMATION ABOUT HEXAMINE:

Hexamine Hazards:
The routes of exposure to Hexamine include; eye contact, skin contact, inhalation and ingestion.

Eye exposure to hexamine may result in redness and slight abrasive damage.
The discomfort is only expected to be short term

Skin contact with hexamine is not thought to have harmful health effects, but irritation can occur after repeated or prolonged exposure, with redness and swelling being possible symptoms.
If an individual has open cuts or wounds however, they should avoid handling the chemical without the proper PPE as this can result in the chemical entering the bloodstream which will produce greater harm than skin contact alone.

Inhalation of hexamine is mainly a concern for those with an already compromised respiratory function with healthy individuals likely to be unharmed.

When the hexamine evaporates and the ammonia component evaporates into a vapour however, inhalation will be more harmful; causing coughing, vomiting and reddening of the lips mouth, nose and throat.
High concentrations of vapour inhalation may cause difficulty in breathing, tightness in the chest, lung damage and even death by suffocation.

In small quantities, the human metabolism allows for detoxification of ammonia.
In doses larger than 1-2g however, ingestion is likely to lead to; nausea, vomiting and diarrhoea.
Very large doses may produce a drop in blood pressure, collapse, central nervous system disorders, spasms, drowsiness, respiratory paralysis and haemolysis.

Hexamine Safety:
If hexamine enters the eye, flush out the eyes immediately with fresh running water remembering to wash under the eyelids as well.
Removing contact lenses should only be performed by skilled personnel.
Seek medical attention if pain persists.
In the event of skin exposure; remove all contaminated clothing, footwear and accessories and cleanse the affected area with plenty of soap and water.
Contaminated clothing must be washed prior to wearing again.
Seek medical attention if irritation occurs.
If hexamine dust is inhaled, remove the person from the contaminated area and encourage the patient to blow their nose to ensure a clear passage for breathing.
If irritation persists, seek medical attention.
In the event of ingestion, vomiting should not be induced.
If vomiting occurs, lean the patient forward or place them on their left side to maintain an open airway and to prevent aspiration.
Observe the patient and seek medical advice.

Hexamine Safety Handling:
Safety showers and emergency eyewash fountains should be accessible in the immediate area of the potential exposure to the chemical.
Ensure the area has adequate ventilation and install local exhaust ventilation if necessary.
Wear proper PPE, such as safety glasses with side shields, chemical goggles, gloves, overalls, aprons, and respirators.
Some plastic PPE is not recommended when handling hexamine, as they may produce static electricity.




SYNONYMS OF HEXAMINE:
Depositor-Supplied Synonyms:
methenamine
Hexamethylenetetramine
100-97-0
Hexamine
Urotropine
Aminoform
Urotropin
Hexamethylenamine
Hexamethylene tetramine
1,3,5,7-Tetraazaadamantane
HMTA
Methenamin
Uritone
Hexamethylenetetraamine
Formamine
Aminoformaldehyde
Ammonioformaldehyde
Ammoform
Antihydral
Cystamin
Cystogen
Duirexol
Hexaform
Hexaloids
Metramine
Resotropin
Uratrine
Urodeine
Xametrin
Formin
Heterin
Hexasan
Uramin
Preparation AF
Hexamethyleneamine
Hexilmethylenamine
Hexa-Flo-Pulver
Ekagom H
methenaminum
Aceto HMT
Herax UTS
Hexamethylentetramin
Metenamina
Hexaminum
Formin (heterocycle)
Nocceler H
Sanceler H
Hexamine (heterocycle)
Vulkacit H 30
Hexamethylentetraminum
1,3,5,7-Tetraazatricyclo[3.3.1.13,7]decane
Hexamethylentetramine
Hexasan (VAN)
S 4 (heterocycle)
Hexamethylenetetraminum
Uro-phosphate
1,3,5,7-tetraazatricyclo[3.3.1.1~3,7~]decane
Esametilentetramina
Metenamine
Methamin
Vesaloin
Hexa (vulcanization accelerator)
1,3,5,7-Tetraazatricyclo (3.3.1.1(3,7))decane
HMT
Hexamine (JAN)
Hexamine (TN)
1,3,5,7-Tetraazatricyclo(3.3.1.13,7)decane
Hexamethylenetetramine (aliphatic)
Methenamine (USP/INN)
NSC-26346
J50OIX95QV
1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 37))decane
CHEBI:6824
H.M.T.
INS NO.239
INS-239
1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane
Formin (the heterocyclic compound)
NSC26346
Silver Methenamine
1,3,5,7-tetraazatricyclo[3.3.1.1^{3,7}]decane
MFCD00006895
NSC-403347
1,3,5,7-Tetraazatricyclo(3.3.1.1(sup 3,7))decane
NCGC00094719-04
E239
HEXAMINE [JAN]
Hexamine Silver
DSSTox_CID_692
E-239
Hexamethylenetetramine-palladium chloride adduct
Methenamine Silver
DSSTox_RID_75739
DSSTox_GSID_20692
1,3,5,7-Tetraazatricyclo[3.3.1.1(3,7)]decane
Caswell No. 482
Methenamine [USAN:INN]
Sanceler HT
Metenamina [INN-Spanish]
Methenaminum [INN-Latin]
Heksa K
Hexamine Superfine
Nocceler H-PO
Sanceler HT-PO
Hexa B
1,3,5,7-Tetraazatricyclo(3.3.1.13,7)decane hydroiodide
CAS-100-97-0
Esametilentetramina [Italian]
Hexamethylentetramin [German]
SMR000857139
Cohedur H 30
CCRIS 2297
HSDB 563
hexamethylene-tetramine
NSC403347
Rhenogran HEXA 80
Thixon 715B
1,3,5,7-Tetraazotricyclo[3.3.1.13,7]decane
SR-05000002024
Methenamine [USP:INN]
1,3,5,7-Tetraazatricyclo[3.3.1.1{3,7}]decane
EINECS 202-905-8
NSC 26346
UN1328
UNII-J50OIX95QV
1,3,5,7-Tetraazatricyclo[3.3.1.1(sup 3,7)]decane
EPA Pesticide Chemical Code 045501
NSC 403347
Hexamethylamine
Naphthamine
Urisol
Carin
EL 10 (corrosion inhibitor)
Hexamethylenetetramine solutions
AI3-09611
HEXAMETHYLENETETRAMINE, ACS
EL 10
Prestwick_79
Vulkacit H30
1,3,5,7-Tetraazatricyclo[3.3.1.13,7 ]decane
Grasselerator 102
Cystex (Salt/Mix)
hexam-ethylenetetraamine
hexamethylene tetraamine
Spectrum_000991
METHENAMINE [MI]
Spectrum2_000827
Spectrum3_001730
Spectrum4_000872
Spectrum5_001603
Methenamine (Mandelamine)
METHENAMINE [INN]
Formaldehyde-ammonia 6:4
[16]-Adamazane, INN
component of Uro-Phosphate
METHENAMINE [HSDB]
METHENAMINE [INCI]
Uro-phosphate (Salt/Mix)
1,5,7-Tetraazaadamantane
EC 202-905-8
Hexamethylentetramin(german)
METHENAMINE [VANDF]
Hexamethylenetetramine, 8CI
METHENAMINE [MART.]
1,3,5,7-tetraazatricyclo[3.3.1.1?,?]decane
SCHEMBL33785
BSPBio_003380
Hexamethylenetetramine, tech.
KBioGR_001563
KBioSS_001471
METHENAMINE [USP-RS]
METHENAMINE [WHO-DD]
Hexamethylenetetramine [UN1328] [Flammable solid]
MLS001332361
MLS001332362
MLS002207085
DivK1c_000322
SPECTRUM1500394
SPBio_000753
Hexamethylenetetramine, BioXtra
CHEMBL1201270
DTXSID6020692
GTPL10913
HMS501A04
KBio1_000322
KBio2_001471
KBio2_004039
KBio2_006607
KBio3_002600
NINDS_000322
HMS1920L13
HMS2091D08
HMS2233B09
HMS3371O15
HMS3652A05
HMS3715D17
METHENAMINE [EP MONOGRAPH]
Pharmakon1600-01500394
METHENAMINE [USP MONOGRAPH]
HY-B0514
STR00289
Tox21_113455
Tox21_201606
Tox21_300502
CCG-40289
Hexamethylenetetramine, LR, >=99%
NSC757101
s3139
STL197471
ZINC86040406
AKOS000120003
AKOS005169648
Tox21_113455_1
Urotropine 100 microg/mL in Methanol
DB06799
NSC-757101
IDI1_000322
NCGC00094719-01
NCGC00094719-02
NCGC00094719-03
NCGC00094719-05
NCGC00094719-06
NCGC00094719-08
NCGC00254463-01
NCGC00259155-01
SBI-0051439.P003
FT-0627024
FT-0669190
H0093
Hexamethylenetetramine, ReagentPlus(R), 99%
SW199604-2
1,5,7-Tetraazatricyclo[3.3.1.13,7]decane
D00393
Hexamethylenetetramine, ACS reagent, >=99.0%
Q71969
AB00052038_08
AB00052038_09
1,3,5,7-tetraaza-tricyclo[3.3.1.13,7]decane
1,3,5,7-tetraazatricyclo-[3.3.1.13,7]decane
1,3,5,7-tetraazatricyclo[3,3,1,13,7]decane
1,5:3,7-Dimethano-1,3,5,7-tetraazacyclooctane
AE-641/00560026
WLN: T66 B6 A B-C 1B I BN DN FN HNTJ
Hexamethylenetetramine [UN1328] [Flammable solid]
Hexamethylenetetramine, analytical reference material
Hexamethylenetetramine, p.a., ACS reagent, 99.0%
Hexamethylenetetramine, SAJ first grade, >=98.5%
J-000293
J-521456
SR-05000002024-1
SR-05000002024-3
1,3,5,7-tetraaza-tricyclo[3.3.1.1*3,7*]decane
1,3,5,7-Tetraazatricyclo-[3.3.1.1(3,7)]decane
BRD-K30114692-001-10-0
Hexamethylenetetramine, JIS special grade, >=99.0%
F2173-0429
Z362014242
Methenamine, European Pharmacopoeia (EP) Reference Standard
1,3,5,7-TETRAAZATRICYCLO(3.3.1.1 SUP(3,7))DECANE
Methenamine, United States Pharmacopeia (USP) Reference Standard
Hexamethylenetetramine, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99.0%
Hexamethylenetetramine, meets analytical specification of Ph.??Eur., BP, 99-100.5% (calc. to the dried substance)
Hexamethylenetetramine, puriss. p.a., Reag. Ph. Eur., >=99.5% (calc. to the dried substance)
1,3,5,7-tetraazaadamantane
1,3,5,7-tetraazatricyclo[3.3.1.1(3,7)-]decane
1,3,5,7- tetrazatricyclo(3.3.1.1*3.7)decane
aceto HMT (= aceto hexamethylenetetramine)
aminoform
aminoformaldehyde
ammoform
ammonioformaldehyde
amoform
antihydral
carin
cystamin
cystogen
duirexol
ekagom H
formaldehyde:ammonia 6:4
formamine
formin
formine
herax UTS
heterin
hexa (= hexamethylenetetramine)
hexa-flo-pulver
hexaform
hexamethylenamine
hexamethyleneamine
Hexamethylenetetramine
hexasan
hexilmethylenamine
HMT (= hexamethylenetetramine)
HMTA (= hexamethylenetetramine)
mandelamine
methamin
methenamine
metheneamine
metramine
naphthamine
preparation AF
resotropin
URAMIN
uratrine
urisol
uritone
urodeine
urotropin
urotropine
vesaloin
vesalvine
vulkacit H30
xametrin
xametrine
HEXAMINE

Hexamine, also known as methenamine, is a chemical compound with the molecular formula C6H12N4.
Hexamine is a white crystalline solid that is highly soluble in water and has a characteristic odor.
Hexamine is derived from formaldehyde and ammonia and is commonly used in various industrial and commercial applications due to its unique properties.

CAS Number: 100-97-0
EC Number: 202-905-8



APPLICATIONS


Hexamine tablets are used for outdoor cooking and heating during camping.
Military personnel rely on hexamine tablets for field rations and warmth.
Hexamine is a go-to solution for emergency heating during power outages.
Survival kits often include hexamine tablets for fire starting and warmth.

Hexamine's role in explosives contributes to their detonation properties.
Hexamine strengthens rubber products as a vulcanizing agent in the rubber industry.
Hexamine is vital in producing synthetic resins used in adhesives and coatings.
The textile industry benefits from hexamine's crease resistance enhancement.

Hexamine's antiseptic properties are utilized in medical treatments.
Hexamine catalyzes reactions, aiding in the production of various compounds.
Hexamine cross-links polymers, improving plastics and resin materials.
Water treatment employs hexamine for pH control and corrosion prevention.

Historically, hexamine was used in photographic developers and fixers.
Adhesive formulations are improved by incorporating hexamine.
Its dehydrating properties are valuable in moisture-sensitive processes.
Hexamine tablets are a reliable choice for igniting fires quickly.

In textile printing, hexamine enhances color fastness.
Agriculture benefits from hexamine as a chemical intermediate.
Hexamine contributes to the synthesis of certain pharmaceuticals.
Analytical chemistry employs hexamine as a reagent for ion determination.
Hexamine enhances properties in fiberboard production and electronics.
Hexamine generates gases for inflating airbags in vehicles.

In oil and gas, Hexamine prevents corrosion in pipelines and equipment.
Hexamine is explored for flame-retardant applications in electronics.
Hexamine serves as a precursor in the production of specific fertilizers.

Hexamine tablets are a reliable choice for igniting charcoal grills and barbecues.
In marine and shipping industries, hexamine is used as a corrosion inhibitor for engine cooling systems.

Hexamine's stabilizing effect on resins improves their shelf life and handling characteristics.
Hexamine contributes to the adhesion and bonding properties of coatings and paints.
Hexamine acts as a catalyst in the production of foamed plastics used in insulation.
Hexamine finds use in the synthesis of specialty chemicals, such as corrosion inhibitors and dye intermediates.

Hexamine's water treatment applications extend to cooling tower systems to prevent scaling and corrosion.
Hexamine is utilized in the manufacture of tablet disinfectants for water purification.
Hexamine is used as a fuel in solid-fuel rocket propellants due to its controlled energy release.

In the automotive industry, hexamine is used in airbag inflators for rapid gas generation during deployment.
Hexamine serves as a corrosion inhibitor for protecting metals in industrial water systems and pipelines.
Hexamine's combustion properties are applied in flameless ration heaters for military field rations.

In mining, hexamine is used as a flotation reagent to separate valuable minerals from ores.
Hexamine finds a place in the production of brake linings, improving friction properties in automotive brakes.
Hexamine is used in the synthesis of melamine-formaldehyde resins for durable laminates and coatings.
In petroleum refining, hexamine is employed in desulfurization processes to remove sulfur compounds.
Hexamine acts as a curing agent in foundry resins, aiding in mold and core production for metal casting.

Hexamine's antimicrobial properties are harnessed in wood preservation treatments.
Hexamine plays a role in the production of synthetic diamond abrasives for industrial applications.
Hexamine is used in the production of certain types of explosives, such as hexamine nitrate.
Hexamine contributes to the production of fuel tablets used in beverage can stoves and portable heaters.
Hexamine is employed as a stabilizer in emulsions and dispersions in the cosmetic industry.

In electronics, Hexamine can be used in circuit board production for flame-resistant materials.
Hexamine's controlled gas release is utilized in airbag cushions for vehicle safety systems.
Hexamine is explored for its potential in wastewater treatment to remove heavy metals.

Hexamine is used in the production of firework compositions, contributing to colorful and controlled pyrotechnic displays.
Hexamine acts as a corrosion inhibitor in cooling systems of power plants to prevent damage to critical components.
Hexamine is employed as a binder in the manufacture of carbon electrodes used in electrolytic cells.

In the leather industry, it is used as a curing agent for tanning agents, enhancing leather's quality and durability.
Hexamine's gas-releasing properties find use in airbag modules for rapid inflation during vehicle collisions.
Hexamine is utilized in the production of automotive catalytic converters, aiding in pollutant emission reduction.
Hexamine is explored as a potential fuel for fuel cells, contributing to clean and efficient energy conversion.

In the construction industry, hexamine is added to cement admixtures to improve workability and strength.
Hexamine serves as a nitrogen source in certain microbial culture media used in microbiology research.
Hexamine is used as a chelating agent in the recovery of precious metals from electronic waste.
Hexamine contributes to the formulation of metal cleaning compounds, removing oxides and impurities.

In the textile industry, hexamine enhances the color retention and colorfastness of fabrics.
Hexamine is employed as a cross-linking agent in the synthesis of epoxy resins for coatings and adhesives.
Hexamine acts as a binder in the production of ceramic materials, enhancing their mechanical properties.
Hexamine's gas-generating properties are utilized in inflating life-saving devices like life jackets.

In the food industry, it can be used as a preservative in certain products to extend shelf life.
Hexamine is a component of artificial urinary calculi used in testing and calibrating medical equipment.
Hexamine serves as a pH buffer in chemical reactions and processes requiring controlled acidity or alkalinity.

Hexamine is used as a corrosion inhibitor in steam generation systems to protect metal surfaces.
Hexamine finds use in the production of controlled-release fertilizers, enhancing nutrient availability to plants.
Hexamine is explored for potential use in the production of biodegradable plastics.
In the production of specialty papers, it can be used to improve wet-strength properties.

Hexamine's presence in detergents aids in soil removal and dispersion during washing.
Hexamine is utilized in the manufacturing of insulating materials used in electronics and electrical equipment.
Hexamine's diverse properties find applications in various research fields, from materials science to analytical chemistry.

Hexamine is a key component in the production of urea-formaldehyde resins used in wood products like particleboard and plywood.
Hexamine is employed as a cross-linking agent in the formulation of adhesives used in woodworking and construction.
In the automotive industry, hexamine is utilized in catalytic converter coatings to reduce harmful emissions.

Hexamine is used in the manufacture of gas masks and respiratory protective equipment filters for defense and industrial applications.
Hexamine serves as a reagent in the synthesis of complex organic compounds in pharmaceutical research.
In the manufacture of automotive tires, hexamine can be used to improve the bonding of rubber compounds.
Hexamine's role as a corrosion inhibitor extends to marine applications, protecting shipboard equipment and structures.

Hexamine is utilized in the production of water-based cutting fluids and coolants for metalworking processes.
Hexamine is added to certain fuel formulations to enhance combustion efficiency and reduce engine emissions.
In the cosmetic industry, it can be used as a stabilizer in emulsions and creams, improving product texture.

Hexamine is employed in the production of polymeric materials with controlled release properties, such as drug delivery systems.
Hexamine finds use in the production of refractory materials used in high-temperature applications like furnaces and kilns.
Hexamine's cross-linking properties contribute to the strength and durability of rubber conveyor belts used in industries.

In the mining industry, hexamine is used in ore flotation processes to separate valuable minerals from gangue.
Hexamine can be added to gas and oil well drilling fluids as a corrosion inhibitor and stabilizer.
Hexamine's role as a flame retardant makes it valuable in the production of fire-resistant textiles and materials.

In the aerospace industry, it is used in rocket propellants for controlled energy release during combustion.
Hexamine is explored for its potential in the treatment of wastewater containing heavy metal pollutants.

Hexamine is used in the production of epoxy composites for aerospace and engineering applications.
Hexamine's controlled gas generation properties are utilized in airbag cushions for passenger safety.
In the electronics industry, it can be used as a resin additive to enhance flame resistance in circuit boards.
Hexamine's binding properties contribute to the formulation of foundry cores used in metal casting.

Hexamine is added to some toothpaste formulations as an abrasive for cleaning and polishing teeth.
Hexamine's gas-releasing characteristics make it useful in inflating airbags in safety vests and lifebuoys.
In the energy sector, hexamine is explored for its potential use as a clean-burning fuel source in solid oxide fuel cells.



DESCRIPTION


Hexamine, also known as methenamine, is a chemical compound with the molecular formula C6H12N4.
Hexamine is a white crystalline solid that is highly soluble in water and has a characteristic odor.
Hexamine is derived from formaldehyde and ammonia and is commonly used in various industrial and commercial applications due to its unique properties.

Hexamine, also known as methenamine, is a versatile chemical compound with a distinct crystalline appearance.
Hexamine forms colorless, odorless crystals that are highly soluble in water.
Hexamine derives its name from its structure, consisting of six carbon atoms linked to four nitrogen atoms.
Hexamine is commercially available in the form of white powder or tablets.

Hexamine has a wide range of applications across industries due to its unique properties.
When heated, hexamine undergoes sublimation, meaning it transitions directly from a solid to a gas.
Hexamine is known for its ability to release nitrogen gas when heated, making it useful in various applications.

Hexamine's combustion releases energy and heat, making it suitable for heating and cooking in outdoor settings.
Hexamine has a distinctive mild, ammonia-like odor when burned.
Hexamine tablets are commonly used by campers, hikers, and military personnel as portable heat sources and cooking fuel.

Hexamine's heat-releasing properties are harnessed in emergency situations and survival kits.
Hexamine's stability and low toxicity make it a preferred choice for many applications.
In the rubber industry, hexamine acts as a vulcanizing agent, enhancing the durability and strength of rubber products.

Hexamine is used as a cross-linking agent in the production of synthetic resins, contributing to their toughness and rigidity.
Hexamine plays a role in the textile industry by improving crease resistance and dimensional stability of fabrics.

Hexamine's antiseptic properties make it valuable in medical applications, particularly for treating urinary tract infections.
Hexamine's molecular structure and properties have led to its use in various chemical reactions as a catalyst or reactant.
Hexamine's role in explosives lies in its ability to release nitrogen gas upon heating, contributing to explosive power.

Hexamine has been historically used in photography as part of photographic developers and fixers.
Hexamine has a long shelf life and is relatively stable when stored under proper conditions.
Its water-soluble nature makes it useful in water treatment processes, helping to control pH and prevent corrosion.
Hexamine's dehydrating properties find applications in diverse industries, including the production of plastics and resins.

As a fire starter, hexamine tablets offer a reliable ignition source for campfires and stoves.
Hexamine's inclusion in cigarette filters aims to reduce the content of tar and nicotine in cigarette smoke.
Hexamine's multifaceted properties make it a valuable chemical compound across various sectors, from outdoor adventures to industrial processes.



PROPERTIES


Molecular Formula: C6H12N4
Molecular Weight: 140.19 g/mol
Appearance: White crystalline solid
Odor: Characteristic ammonia-like odor when burned
Solubility: Highly soluble in water
Melting Point: Approximately 263-281°C (505-538°F)
Boiling Point: Decomposes without a well-defined boiling point
Density: Approximately 1.33 g/cm³ (at 20°C)
Sublimation Point: Begins to sublime around 280°C (536°F)
Vapor Pressure: Low vapor pressure at room temperature



FIRST AID


Inhalation:

If inhaled, move the affected person to fresh air immediately.
If breathing is difficult, provide oxygen if available and seek medical attention.
If the person's breathing has stopped, administer artificial respiration and seek medical help.


Skin Contact:

Remove contaminated clothing and footwear.
Wash the affected skin area thoroughly with soap and water.
If irritation, redness, or rash develops, seek medical attention.
If the compound has entered under the skin (subcutaneous), seek medical assistance.


Eye Contact:

Rinse the eyes gently but thoroughly with water for at least 15 minutes, holding the eyelids open.
Remove contact lenses if present and easy to do so, but continue rinsing.
Seek immediate medical attention if irritation, redness, or pain persists.


Ingestion:

Do not induce vomiting unless instructed by medical professionals.
Rinse the mouth with water if the person is conscious and able to swallow.
Seek medical attention immediately. Provide medical personnel with information about the compound ingested.



HANDLING AND STORAGE


Handling:

Ventilation:
Work with hexamine in a well-ventilated area or use local exhaust ventilation to prevent the buildup of vapors or dust in the air.

Personal Protective Equipment:
Wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and protective clothing, to minimize skin and eye contact.

Avoid Inhalation:
Avoid inhaling hexamine dust, fumes, or vapors.
Use respiratory protection, such as a dust mask or respirator, when working with the compound in areas with inadequate ventilation.

Prevent Contact:
Avoid skin and eye contact with hexamine.
If handling the compound, do not touch your face, especially your eyes, nose, or mouth, without washing your hands first.

No Smoking:
Prohibit smoking, eating, or drinking in areas where hexamine is being handled to prevent ingestion or inhalation of the compound.

Work Practices:
Minimize dust generation by using appropriate handling techniques, such as using closed systems or wet methods.

Static Electricity:
Take precautions to avoid static electricity buildup, which could ignite hexamine dust.
Use grounding equipment if necessary.

Spill Management:
In case of spills, use appropriate spill containment measures to prevent the spread of hexamine.
Clean up spills promptly and safely.


Storage:

Store in a Cool, Dry Place:
Store hexamine in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and open flames.

Containers:
Keep hexamine in tightly closed containers to prevent contamination and exposure to moisture.

Separation:
Store hexamine away from incompatible materials, such as strong acids, strong bases, and oxidizing agents.

Labeling:
Clearly label storage containers with the name of the substance and appropriate hazard warnings.

Fire Protection:
Store hexamine away from flammable materials and ignition sources to prevent fire hazards.

Controlled Access:
Limit access to storage areas to authorized personnel only, and keep storage areas locked when not in use.

Emergency Procedures:
Ensure that appropriate emergency equipment, such as spill control materials and fire extinguishers, are available near storage areas.

Segregation:
Segregate hexamine from food, beverages, and medical supplies to prevent cross-contamination.


Transportation:

Compliance:
Follow all transportation regulations and guidelines for handling and transporting hazardous materials, if applicable.

Packaging:
Use approved packaging materials and containers for transporting hexamine to prevent leakage or breakage.

Documentation:
Ensure that all required documentation, including safety data sheets (SDS) and shipping documents, accompany the shipment.

Avoid Rough Handling:
Handle transportation containers carefully to avoid damage and potential leaks.



SYNONYMS


Methenamine
Urotropine
Hexamethylenetetramine
Formin
Aminoform
Aminoformaldehyde
Hexamine
Urotropin
Urotem
Urotropinum
Hexamethyleneamine
Hexaminol
Hexamethylenamine
Aminoformyl
Cystogen
Formamine
HMTA
Methylenamin
Uretropin
Urotropinum
Urotrupin
Hexamethylenamin
Hexaform
Methenamine Solid
Hexamethylenetetraamine
Urotropine
Aminohexamethylene
Aminoformaldehyde
Methenamine
Hexamethylenamine
HMTA
Aminoform
Hexamethylenetetramine
Urotrupin
Hexamine
Methenamine solid
Aminoformyl
Formamine
Urotropin
Hexaminol
Urotropinum
Urotropinum
Uretropin
Hexaform
Hexaminum
Hexamethylenamin
Methylenamin
Aminoformaldehyde
Aminoform
Cystogen
Hexamine
Hexamethylenetetramine; Hexamine; 1,3,5,7- Tetraazaadamantane; Ammonioformaldehyde; Aceto HMT; Aminoform; Ammoform; Cystamin; Cystogen; Esametilentetramina (Italian); Formamine; Formin; Hexaform; Urotropin; Hexamethyleneamine; Hexamethylentetramin (German); Hexilmethylenamine; HMT; Methamin; Methenamine; Resotropin; Uritone; Urotropine; Esametilentetramina (Italian) CAS NO:100-97-0
HEXAMOLL DINCH
HEXANAL, N° CAS : 66-25-1, Nom INCI : HEXANAL, Nom chimique : Caproic Aldehyde, N° EINECS/ELINCS : 200-624-5. Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit
HEXANDEDIHYDRAZIDE
Hexanedihydrazide is a chemical used for cross-linking water-based emulsions.
Hexanedihydrazide can also be used as a hardener for certain epoxy resins.
Hexanedihydrazide is a symmetrical molecule with a C4 backbone, and the reactive group is C=ONHNH2.

CAS Number: 1071-93-8
EC Number: 213-999-5
Molecular Formula: C6H14N4O2
Molecular Weight: 174.20 g/mol

Synonyms: Hexanedihydrazide, Adipic dihydrazide, 1071-93-8, Adipic acid dihydrazide, Adipohydrazide, Hexanedihydrazide, Hexanedioic acid, dihydrazide, Adipyl hydrazide, Hexanediohydrazide, Adipic acid, dihydrazide, Adipoyldihydrazine, adipoyl dihydrazide, VK98I9YW5M, DTXSID0044361, Hexanedioic acid, 1,6-dihydrazide, NSC 3378, NSC-3378, EINECS 213-999-5, NSC 29542, NSC-29542, AI3-22640, WLN: ZMV4VMZ, EC 213-999-5, MFCD00007614, Adipodihydrazide, Adip dihydr, adipic hydrazide, Adipoyl hydrazide, adipic dihydrazone, Hexanedihydrazide #, Adipic aciddihydrazide, Adipic acid dihyrazide, Hexanedioic dihydrazide, AJICURE ADH, QUALIMER ADH, ULTRALINK HYDRAZIDE, Hexanedioic acid dihydrazide, SCHEMBL49856, Adipic Acid Dihydrazide (ADH), CHEMBL3185968, DTXCID8024361, SCHEMBL11037942, AMY3771, NSC3378, 1,4-Butanedicarboxylic dihydrazide, BK 1000Z, BT 1000Z, NSC29542, STR02658, Tox21_301067, BBL022965, STK709135, ADIPIC ACID DIHYDRAZIDE [INCI], AKOS000267183, NCGC00248276-01, NCGC00257525-01, CAS-1071-93-8, A0170, Adipic acid dihydrazide, >=98% (titration), CS-0010116, FT-0621914, EN300-03706, D72486, T 2210, Adipic acid dihydrazide, purum, >=97.0% (NT), A801603, J-660023, Q-200600, Q4682936, Z56812730, F1943-0024, Hexanedihydrazide, Adipic dihydrazide, Adipohydrazide, Adipyl hydrazide, Adipic acid dihydrazide, Adipyl hydrazide, Adipic acid dihyrazide, Hexanedioic acid, dihydrazide, 403, adipohydrazide, Hexanedioic Acid Dihydrazide, ADH, ADH (hydrazide), ADH 4S, ADH-J, ADH-S, Adipic dihydrazide, Adipoyl Dihydrazide, Adipoyl Hydrazide, Adipoyldihydrazine, Ajicure ADH, BK 1000Z, BT 1000Z, NSC 29542, NSC 3378, Qualimer ADH, T 2210, Adipohydrazide, Adipic dihydrazide, adipohydrazide, adipic acid dihydrazide, hexanedioic acid, dihydrazide, adipyl hydrazide, hexanediohydrazide, adipic acid, dihydrazide, adipodihydrazide, hexanedioic acid, 1,6-dihydrazide, unii-vk98i9yw5m, Hexanedioic acid,1,6-dihydrazide, Adipic acid dihydrazide, Hexanedioic acid,dihydrazide, Adipic dihydrazide, Adipoyl hydrazide, ADH, Adipoyl dihydrazide, Adipoyldihydrazine, Qualimer ADH, BT 1000Z, BK 1000Z, NSC 29542, NSC 3378, ADH 4S, ADH (hydrazide), ADH-J, ADH-S, T 2210, Ajicure ADH, Adipic acid dihydrazide, Technicure ADH, Epicure PD 797, 98152-55-7, 124246-54-4, ADH, Adipohydrazide, ADIPODIHYDRAZIDE, adipoyl hydrazide, Adipic dihydrazide, Adipic dihydrazide, ADIPINIC DIHYDRAZIDE, ADIPIC ACID DIHYDRIZIDE, ADIPIC ACID DIHYDRAZIDE

Hexanedihydrazide is a chemical used for cross-linking water-based emulsions.
Hexanedihydrazide is a symmetrical molecule with a C4 backbone and the reactive group is C=ONHNH2.

Hexanedihydrazide is a latent hardener for epoxy resin.
Dihydrazides are made by the reaction of an organic acid with hydrazine.
Other dihydrazides with different backbones are also common, including isophthalic dihydrazide (IDH) and sebacic dihydrazide (SDH).

Hexanedihydrazide is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Hexanedihydrazide is an effective crosslinking agent, curative and hardener.

Hexanedihydrazide is the most common dihydrazide crosslinking agent within a series of dihydrazides such as sebacic dihydrazide (SDH) and isophthalic dihydrazide (IDH).
Hexanedihydrazide’s has a melting point of 180 °C and a molecular weight of 174; both are lower than the alternative dihydrazides SDH and IDH.

Hexanedihydrazide is a symmetrical molecule with a C4 backbone and the reactive group is C=ONHNH2.
Dihydrazides are made by the reaction of an organic acid with hydrazine.
Other dihydrazides with different backbones are also common, including isophthalic dihydrazide (IDH) and sebacic dihydrazide (SDH).

The applications of Hexanedihydrazide are facilitated by the nucleophilicity of the amine function (good reaction characteristics), the good overall properties and weatherability of cured systems.
The moderate solubility of Hexanedihydrazide in water (50 g./liter) and common organic solvents facilitates the use of Hexanedihydrazide in aqueous and solvent based systems.

The cure temperature for epoxy resins (glycidyl types) formulated with Hexanedihydrazide is influenced by the melt-out temperature of the Hexanedihydrazide, which allows an extended pot life at low temperatures.
Storage stability can be up to six-months at room temperature, with cure times of about one-hour at 130 °C.

Cure rates can be accelerated using tin or titanate catalysts, or imidazoles.
One-component Hexanedihydrazide epoxy systems can be partially cured or “B-staged”, and later fully cured.
B-staging provides handling, processing, and fabrication advantages.

Hexanedihydrazide is a distinctive crosslinking agent and curative that provides controlled reactivity and performance improvements in epoxy resins, polyurethane dispersions (PUDs), solvent-based polyurethanes (PURs), and emulsion acrylic resins.
Hexanedihydrazide finds major applications as a latent curing agent for B-stageable epoxy resins and as an ambient temperature crosslinking agent for high-performance acrylic emulsion architectural coatings.
Materials crosslinked or cured with Hexanedihydrazide demonstrate excellent colour stability, weathering resistance, adhesion, durability, hardness, and toughness.

Hexanedihydrazide is a chemical used for cross-linking water-based emulsions.
Hexanedihydrazide can also be used as a hardener for certain epoxy resins.

Hexanedihydrazide is a symmetrical molecule with a C4 backbone, and the reactive group is C=ONHNH2.
Dihydrazides are made by the reaction of an organic acid with hydrazine.
Other dihydrazides with different backbones are also common, including isophthalic dihydrazide (IDH) and sebacic dihydrazide (SDH).

Homobifunctional cross-linking reagent that is specific for aldehydes resulting in relatively stable hydrazone linkages.
This is commonly used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation.

Hexanedihydrazide acts as a reducing agent in organic synthesis.
Hexanedihydrazide reduces aldehydes and ketones to alcohols, and Hexanedihydrazide reduces nitro compounds to amines.
Hexanedihydrazide also acts as a catalyst in the production of polyurethane foams, and Hexanedihydrazide is used as a cross-linking agent in polymers.

Hexanedihydrazide is used as a formaldehyde scavenger and reacts with formaldehyde, thereby preventing the volatilizing of formaldehyde in the air.
Hexanedihydrazide is also employed as a paint additive and coating additive.

Hexanedihydrazide is also used as an intermediate.
Further, Hexanedihydrazide is used for cross-linking water-based emulsions and as a hardener for certain epoxy resins, which finds application in powder coating.

Hexanedihydrazide is a homobifunctional cross-linking reagent that is specific for aldehydes.
This results in relatively stable hydrazone linkages.

Hexanedihydrazide is generally used in the linking of glycoproteins, like antibodies, in a site-specific fashion following periodate oxidation.
Oxidation and coupling may be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.

Hexanedihydrazide is the most suitable hydrazide cross-linking agent, and Hexanedihydrazide has been widely used in water-based paint emulsions in combination with diacetone acrylamide.
Hexanedihydrazide is weakly alkaline, and there is a possibility of agglomeration when solid Hexanedihydrazide is added directly to the emulsion, so usually Hexanedihydrazide should be dissolved in hot water before use.

Applications of Hexanedihydrazide:
Hexanedihydrazide is used as a formaldehyde scavenger and reacts with formaldehyde, thereby preventing the volatilizing of formaldehyde in the air.
Hexanedihydrazide is also employed as a paint additive and coating additive.

Hexanedihydrazide is also used as an intermediate.
Further, Hexanedihydrazide is used for cross-linking water-based emulsions and as a hardener for certain epoxy resins, which finds application in powder coating.

Hexanedihydrazide has been used:
Hexanedihydrazide is used in the preparation of reactive premix to synthesize the porous biomaterial.
Hexanedihydrazide is used for the crosslinking of methacrylated chondroitin sulfate (MA-CS) coating using carbodiimide-based chemistry for the production and characterization of methacrylated chondroitin sulfate magnetic nanoparticles (MA-CS MNPs).

Hexanedihydrazide is used for the covalent labeling of rhamnolipids, pyochelin, and vancomycin with Abberior STARNHS ester dye.
Hexanedihydrazide is used as a difunctional crosslinking agent in paints and coatings for certain water-based acrylic emulsions.

Hexanedihydrazide is used as a hardener for epoxy resins and a chain extender for polyurethanes.
A small use is as a formaldehyde scavenger preventing the liberation of formaldehyde.

Hexanedihydrazide is Applied in The Production of:
Crosslinking Agent for Polymers
Elastomers and Rubber Industry
Adhesives and Sealants
Coatings and Paints
Textile Industry
Corrosion Inhibitors
Biomedical Applications
Photography
Water Treatment
Fuel Additives
Polymer Modification

Uses of Hexanedihydrazide:
Hexanedihydrazide is used to functionalize magnetic nanoparticles for glycopeptide enrichment and identification.
Hexanedihydrazide is a homobifunctional cross-linking reagent specific for aldehydes resulting in relatively stable hydrazone linkages.

Hexanedihydrazide is typically, used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation.
Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.

Hexanedihydrazide can also be used as a chain extension for liquid rubber.
Hexanedihydrazide can also be used as a hardener for certain epoxy resins.

Hexanedihydrazide is used adhesives and sealant chemicals, and Automotive care products.
Hexanedihydrazide is used for epoxy powder coating curing agent and coating additives, Metal deactivator and other polymer additives and water treatment agent.

Hexanedihydrazide is the most suitable hydrazide crosslinking agent.
Hexanedihydrazide and diacetone acrylamide have been widely used in water-based paint emulsion.
Hexanedihydrazide is weakly alkaline, solid Hexanedihydrazide is directly added to the emulsion may produce coalescence, usually Hexanedihydrazide should be dissolved in hot water (poor solubility in cold water) and reused.

Hexanedihydrazide bifunctional compound, which can be cross-linked with sodium hyaluronate as a protein drug carrier.
Hexanedihydrazide plays a cross-linking role with diacetone acrylamide in the post-crosslinking of water emulsion and water-soluble polymer, such as water-based coatings, adhesives, fibers, plastic film treatment, hair spray, etc., and can also be used as epoxy powder coating curing agent And water-based coating additives, metal deactivators and other polymer additives and water treatment agents, indoor formaldehyde adsorbents and intermediate raw materials.

The same type of bifunctional linker for aldehydes can produce relatively stable hydrazone linkage; for the linkage of carbohydrate proteins, such as antibodies, periodate oxidation reaction occurs at a specific form of position; at pH 5.0, oxidation reaction and coupling reaction can be carried out conveniently, hydrazide derived from low pKa value can avoid competitive reaction through primary amine.

Hexanedihydrazide is mainly used for epoxy powder coating curing agent and coating additives, metal deactivator and other polymer additives and water treatment agents.
Hexanedihydrazide is used as a crosslinking agent in acrylic emulsion with ketone group.

Hexanedihydrazide is used in epoxy adhesives and sealants.
Hexanedihydrazide is used crosslinking agent for self crosslinking emulsion resins using DAAM.
Hexanedihydrazide, also known as ADH or Adipohydrazide, can be used as a hardener for epoxy resins and for cross-linking water-based emulsions.

Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
Hexanedihydrazide is used analytical Reagents, Diagnostic Reagents, Teaching Reagents.

Hexanedihydrazide is used for Biological Purpose, For Tissue Medium Purpose, For Electron Microscopy, For Lens Blooming, Pro Analysis, Super Special Grade, For Scintillation, For Electrophoresis Use, For Refractive Index.
Hexanedihydrazide is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Hexanedihydrazide is used in the following products: coating products, adhesives and sealants, fillers, putties, plasters, modelling clay, finger paints, polymers, non-metal-surface treatment products, textile treatment products and dyes and washing & cleaning products.
The same bifunctional crosslinking reagent, Hexanedihydrazide, is specially used for aldehydes to generate relatively stable hydrazone links.

Other release to the environment of Hexanedihydrazide is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Other release to the environment of Hexanedihydrazide is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

Hexanedihydrazide can be found in complex articles, with no release intended: vehicles covered by End of Life Vehicles (ELV) directive (e.g. personal vehicles or delivery vans).
In particular, Hexanedihydrazide is used to connect glycoproteins, such as antibodies.

Hexanedihydrazide is used in the following products: adhesives and sealants, coating products, paper chemicals and dyes, textile treatment products and dyes and washing & cleaning products.
Hexanedihydrazide is used for the manufacture of: textile, leather or fur and wood and wood products.

Other release to the environment of Hexanedihydrazide is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Hexanedihydrazide is used in the following products: adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, polymers, textile treatment products and dyes and finger paints.
Release to the environment of Hexanedihydrazide can occur from industrial use: formulation of mixtures and formulation in materials.

Hexanedihydrazide is used in the following products: paper chemicals and dyes, coating products, textile treatment products and dyes, adhesives and sealants, finger paints, laboratory chemicals, washing & cleaning products and water treatment chemicals.
Hexanedihydrazide is used for the manufacture of: chemicals, pulp, paper and paper products and plastic products.

Release to the environment of Hexanedihydrazide can occur from industrial use: for thermoplastic manufacture, as an intermediate step in further manufacturing of another substance (use of intermediates), in the production of articles and as processing aid.
Release to the environment of Hexanedihydrazide can occur from industrial use: manufacturing of the substance.

Hexanedihydrazide is a homobifunctional cross-linking reagent specific for aldehydes resulting in relatively stable hydrazone linkages.
Hexanedihydrazide is typically, used in the linking of glycoproteins, such as antibodies, in a site-specific fashion following periodate oxidation.
Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.

Hexanedihydrazide is used to functionalize magnetic nanoparticles for gylcopeptitde enrichment and identification.
Hexanedihydrazide can also be used as a chain extension for liquid rubber.

Hexanedihydrazide is used for synthesis.
Hexanedihydrazide is used as a formaldehyde scavenger and reacts with formaldehyde, thereby preventing the volatilizing of formaldehyde in the air.

Hexanedihydrazide is also employed as a paint additive and coating additive.
Hexanedihydrazide is also used as an intermediate.

Further, Hexanedihydrazide is used for cross-linking water-based emulsions and as a hardener for certain epoxy resins, which finds application in powder coating.
Hexanedihydrazide is widely used as cross-linker in waterborne acrylic emulsions.

Hexanedihydrazide is added to the water phase in a PUD.
Crosslinking occurs during the drying and film coalescence process which is ideal for maximizing the film properties including gloss, scrub, stain and wear resistance and durability.

Other crosslinking methods where crosslinking occurs prior to film coalescence exhibit reduced performance properties including poor flow and leveling.
The full reactivity characteristics of Hexanedihydrazide are ideal for PUR systems.
Alternative curatives which show incomplete crosslinking due to slow reactivity and the lack of curative mobility in a dry film will also compromise performance.

The DAAM/Hexanedihydrazide pair is also used in crosslinkable sizing agents, thickeners, adhesives, and sealants.
Hexanedihydrazide is a unique crosslinking agent and curative, offering controlled reactivity and performance enhancements in epoxy resins, polyurethane dispersions (PUDs), solvent based PURs and emulsion acrylic resins.

The major applications for Hexanedihydrazide are a latent curing agent for B-stageable epoxy resins and an ambient temperature crosslinking agent for high performance acrylic emulsion architectural coatings.
Systems crosslinked or cured with Hexanedihydrazide exhibit good color stability and weathering characteristics, adhesion, durability, hardness, and toughness.

Hexanedihydrazide is a chemical used for cross-linking water-based emulsions.
Hexanedihydrazide can also be used as a hardener for certain epoxy resins.

Hexanedihydrazide is used as a difunctional crosslinking agent in paints and coatings for certain water-based acrylic emulsions.
Hexanedihydrazide is used as a hardener for epoxy resins and a chain extender for polyurethanes.

A small use is as a formaldehyde scavenger preventing the liberation of formaldehyde.
One component epoxy resins are used in coatings such as powder coatings, adhesives including hot melt adhesives, molding compounds and in fiber reinforced composites.

Glass and carbon fiber prepreg obtained by a hot melt impregnation method are used in the fabrication of sporting goods, wind turbine blades and aircraft/aerospace components.
With Hexanedihydrazide cure, epoxy resins exhibit excellent toughness, flexibility, and adhesive properties.

Tg’s of 140-160 °C are achievable using a standard liquid bisphenol A epoxy resin (DGEBA) with Hexanedihydrazide as the hardener.
Rigid and flexible epoxy adhesives have been formulated as one component systems that can be stored at room temperature using Hexanedihydrazide as a latent curing agent.
Rigid epoxy adhesives are based on bisphenol A and novolac epoxides.

These rigid adhesives exhibit excellent cohesive and adhesive properties to a wide variety of surfaces.
Flexible epoxy adhesives produce more pliable bonds which better accommodate bond line stresses or differential substrate expansion rates.

Flexible epoxy resins include aliphatic di- and tri-epoxy resins such as hexanediol diglycidyl ether and poly(oxypropylene) diglycidyl ethers.
Semi-rigid epoxy-based adhesives utilize mixtures of both classes of epoxy resins or rigid formulations using flexibilizers.

Epoxy Resins:
A notable fact with regard to Hexanedihydrazide in epoxy formulations is that each of the primary amine end groups has a functionality of two, so the Hexanedihydrazide molecule has an equivalency of four per epoxy moiety.
Accordingly, the active hydrogen equivalent weight of Hexanedihydrazide is 43.5.
When formulated with epoxy resins, the Hexanedihydrazide index can range between 0.85-1.15 of stoichiometric proportions, without a significant effect on mechanical properties.

Industry Uses:
Adhesion/cohesion promoter
Binder
Hardener
Other (specify)
Paint additives and coating additives not described by other categories
Plasticizer

Consumer Uses:
Hardener
Other
Other (specify)
Paint additives and coating additives not described by other categories

Biochem/physiol Actions of Hexanedihydrazide:
Hexanedihydrazide is a low molecular weight compound that comprises a hydrazide group at each end.
This leads to the supply of extra adsorption sites for heavy metals that maintain or elevate the adsorption capacities of the cross-linked adsorbents.
Hexanedihydrazide is used as a crosslinker in various fields, like making mechanical latexes films and injectable oxidized hyaluronic acid hydrogel.

General Manufacturing Information of Hexanedihydrazide:

Industry Processing Sectors:
Adhesive Manufacturing
Custom Compounding of Purchased Resins
Paint and Coating Manufacturing
Paper Manufacturing
Plastics Product Manufacturing
Printing Ink Manufacturing

Typical Properties of Hexanedihydrazide:
Hexanedihydrazide is physical and chemical properties appearance white crystalline powder
Hexanedihydrazide is soluble in water, slightly soluble in acetone, and acetic anhydride or acid chloride can occur acylation reaction, is an important amide hydrazine compounds.

Hexanedihydrazide serves as a difunctional crosslinking agent in paints and coatings applied to specific water-based acrylic emulsions.
Additionally, Hexanedihydrazide acts as a hardener for epoxy resins and a chain extender for polyurethanes.
Moreover, Hexanedihydrazide finds a minor application as a formaldehyde scavenger, preventing the release of formaldehyde.

Polyurethane Dispersions (Puds):
Hexanedihydrazideis an effective room temperature curative for aqueous PUDs and solution polyurethanes.
In this capacity, Hexanedihydrazide provides polyurea coatings with higher hardness, toughness and adhesion properties, excellent mechanical properties, abrasion and chemical resistance.
Hexanedihydrazide cured polyurethane coatings exhibit good color stability and weathering properties, which is not observed with standard amine curatives.

Handling And Storage of Hexanedihydrazide:

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Tightly closed.
Dry.

Storage stability:

Recommended storage temperature:
20 °C

Stability And Reactivity of Hexanedihydrazide:

Chemical stability:
Hexanedihydrazide is chemically stable under standard ambient conditions (room temperature).

First Aid Measures of Hexanedihydrazide:

If inhaled:

After inhalation:
Fresh air.

In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.

In case of eye contact:

After eye contact:
Rinse out with plenty of water.
Remove contact lenses.

If swallowed:

After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.

Fire Fighting Measures of Hexanedihydrazide:

Extinguishing media:

Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder

Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

Accidental Release Measures of Hexanedihydrazide:

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.

Observe possible material restrictions:
Take up dry.

Dispose of properly.
Clean up affected area.

Exposure Controls/personal Protection of Hexanedihydrazide:

Personal protective equipment:

Eye/face protection:
Use equipment for eye protection.
Safety glasses.

Skin protection:

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min

Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min

Control of environmental exposure:
Do not let product enter drains.

Identifiers of Hexanedihydrazide:
CAS number: 1071-93-8
EC number: 213-999-5
Hill Formula: C₆H₁₄N₄O₂
Molar Mass: 174.2 g/mol
HS Code: 2928 00 90
Flash point: 150 °C
Ignition temperature: 360 °C
Melting Point: 180 - 182 °C
Melting Point: 178.0°C to 182.0°C
Color: White to Yellow
Infrared Spectrum: Authentic
Assay Percent Range: 8%
Linear Formula: H2NNHCO(CH2)4CONHNH2
Beilstein: 02, I, 277
Solubility Information Solubility in water: soluble.
Other solubilities: soluble in acetic acid,slightly soluble in acetone,
insoluble in ethanol,ether and benzene
Formula Weight: 174.2
Percent Purity: 98%
Physical Form: Crystalline Powder

Molecular Weight: 174.20100
Exact Mass: 174.20
EC Number: 213-999-5
UNII: VK98I9YW5M
NSC Number: 29542|3378
DSSTox ID: DTXSID0044361
HScode: 2928000090
PSA: 110.24000
XLogP3: -2.1
Appearance: DryPowder
Density: 1.186 g/cm3
Melting Point: 171 °C @ Solvent: Water
Boiling Point: 519.3ºC at 760 mmHg
Flash Point: > 109ºC
Refractive Index: 1.513
Water Solubility: H2O: soluble
Storage Conditions: -20ºC
Vapor Pressure: 6.92E-11mmHg at 25°C

Properties of Hexanedihydrazide:
Molecular Weight: 174.20 g/mol
XLogP3-AA: -2.1
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 5
Exact Mass: 174.11167570 g/mol
Monoisotopic Mass: 174.11167570 g/mol
Topological Polar Surface Area: 110Ų
Heavy Atom Count: 12
Complexity: 142
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Physical state: powder
Color: white
Odor: No data available
Melting point/freezing point
Melting point/range: 180 - 182 °C - lit.
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 150 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 102 g/l at 20 °C - soluble
Partition coefficient:
n-octanol/water:
log Pow: -2,7 at 20 °C

Vapor pressure: No data available
Density: No data available
Relative density: 1,29 at 20 °C
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Molecular Formula: C6H14N4O2
Molar Mass: 174.2
Density: 1.186g/cm3
Melting Point: 175-182℃
Boling Point: 519.3°C at 760 mmHg
Flash Point: 267.9°C
Water Solubility: soluble
Vapor Presure: 6.92E-11mmHg at 25°C
Appearance: White crystal

Storage Condition: 2-8℃
Sensitive: Sensitive to air
Refractive Index: 1.513
MDL: MFCD00007614
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 519.30 °C. @ 760.00 mm Hg (est)
Flash Point: 514.00 °F. TCC ( 267.90 °C. ) (est)
logP (o/w): -2.670 (est)
Soluble in: water, 3.287e+005 mg/L @ 25 °C (est)
Appearance (Colour): White to pale yellow
Appearance (Form): Powder
Solubility: (Turbidity) 10% aq. solution: Clear
Solubility: (Colour) 10% aq. solution: Colourless to pale yellow
Assay (NT): min. 95.0%
Melting Point: 178 - 182°C
Loss on drying: max. 0.5%

CAS Number: 1071-93-8
Abbreviations: ADH
Beilstein Reference: 973863
ChemSpider: 59505
ECHA InfoCard: 100.012.727
EC Number: 213-999-5
MeSH: Adipic+dihydrazide
PubChem CID: 66117
RTECS number: AV1400000
UNII: VK98I9YW5M
CompTox Dashboard (EPA): DTXSID0044361
InChI: InChI=1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)
Key: IBVAQQYNSHJXBV-UHFFFAOYSA-N
InChI=1/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)
Key: IBVAQQYNSHJXBV-UHFFFAOYAB
SMILES: O=C(NN)CCCCC(=O)NN

Specifications of Hexanedihydrazide:
Color according to Munsell color system: not more intensely colored than reference standard NE12
Assay (HClO₄): ≥ 97.0 %
Melting range (lower value): ≥ 178 °C
Melting range (upper value): ≤ 182 °C
Identity (IR): passes test

Melting Point: 180 - 183 Deg C:
Fe: <0.0005%:
Loss on Drying: <0.5%:
Sulfate: <0.005%:
Assay: >99%:
Methanol: <0.1%:
Non Volatile Matter: <0.01%:
Cl: <0.005%:
Appearance: White crystalline powder:
Hydrazine: <20ppm

Related compounds of Hexanedihydrazide:
hexanedioic acid
Adipic dihydrazide
hexanedioyl dichloride
hexanedinitrile
hexanediamide

Names of Hexanedihydrazide:

Preferred IUPAC name:
Adipic dihydrazide

Other names:
Hexanedihydrazide
Adipohydrazide
Adipyl hydrazide
HEXANE-1,6-DIOL
Hexane-1,6-diol is prepared by the hydrogenation of adipic acid or its esters.
Laboratory preparation could be achieved by reduction of adipates with lithium aluminium hydride, although this method is impractical on a commercial scale.
Hexane-1,6-diol is an organic compound with the formula (CH2CH2CH2OH)2.

CAS: 629-11-8
MF: C6H14O2
MW: 118.17
EINECS: 211-074-0

Hexane-1,6-diol is a colorless water-soluble solid.
Hexane-1,6-diol is a no-irritating to the skin. However, it can be irritative to the respiratory tract and mucous membrane.
Hexane-1,6-diol vapours or dust cause irritation to the eye. Severe eye exposure may cause conjunctivitis, iritis, and diffuse corneal opacity.
A diol that is hexane substituted by hydroxy groups at positions 1 and 6.
Hexane-1,6-diol is a diol compound that has gained significant attention in the scientific community due to its unique properties and potential applications.
Hexane-1,6-diol is a colorless liquid that is soluble in water and organic solvents, and it has a wide range of industrial and scientific applications.

Hexane-1,6-diol Chemical Properties
Melting point: 38-42 °C (lit.)
Boiling point: 250 °C (lit.)
Density: 0.96
Vapor pressure: 0.53 mm Hg ( 20 °C)
Refractive index: 1.457
Fp: 215 °F
Storage temp.: Store below +30°C.
Solubility H2O: 0.1 g/mL, clear, colorless
Form: Waxy Flakes
pka: 14.87±0.10(Predicted)
Color: White
PH: 7.6 (900g/l, H2O, 20℃)
Explosive limit: 6.6-16%(V)
Water Solubility: 500 g/L
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1
Merck: 14,4690
BRN: 1633461
InChIKey: XXMIOPMDWAUFGU-UHFFFAOYSA-N
LogP: 0 at 25℃
CAS DataBase Reference: 629-11-8(CAS DataBase Reference)
NIST Chemistry Reference: Hexane-1,6-diol (629-11-8)
EPA Substance Registry System: Hexane-1,6-diol (629-11-8)

Uses
Hexane-1,6-diol is widely used for industrial polyester and polyurethane production.
Hexane-1,6-diol can improve the hardness and flexibility of polyesters as it contains a fairly long hydrocarbon chain.
In polyurethanes, Hexane-1,6-diol is used as a chain extender, and the resulting modified polyurethane has high resistance to hydrolysis as well as mechanical strength, but with a low glass transition temperature.
Hexane-1,6-diol is also an intermediate to acrylics as a crosslinking agent, e.g. hexanediol diacrylate.
Unsaturated polyester resins have also been made from Hexane-1,6-diol, along with styrene, maleic anhydride and fumaric acid.
Hexane-1,6-diol is used in polymer synthesis such as polyester, polyurethane and nylon.
Hexane-1,6-diol is used as an intermediate to adhesives, acrylics and dyestuffs.
Further, Hexane-1,6-diol is employed in gasoline refining and pharmaceutical production.

Polyurethanes
Hexane-1,6-diol is widely utilized in the manufacture of polyesterols such as sebacates, azelates, and adipates.
Hexane-1,6-diol are resistant to hydrolysis and have low glass transition temperature as well as high mechanical levels.
Hexane-1,6-diol is used as an ingredient in the preparation of a wide range of tailor-made products for numerous specialty and standard applications.

In Acrylics
Hexane-1,6-diol is utilized as an ingredient in the manufacture of the bifunctional hexanediol diacrylate which is a monomer that is normally used in conjunction with other acrylic monomers as a reactive diluent for decorative coatings and printing inks.

In Adhesives
Urethanes and co-terephthalates that are based on Hexane-1,6-diol provide faster better tack properties and crystallization.
Due to its low glass transition property, Hexane-1,6-diol offers high flexibility as well as excellent adhesive properties.

Other Uses
Hexane-1,6-diol is incorporated into the production of other compounds used in polymeric thickeners, sizing agents, plasticizers for polyvinyl chloride, pesticides, and surfactants dyestuffs as a flexible building block.

Quality and Analysis
The assay of the pure product is about 98 %; impurities are various diols and -caprolactone as well as traces of water.
The color number of the product determined photometrically according to the Pt/Co scale must not exceed 15 APHA.
Above 70 ℃, Hexane-1,6-diol tends to turn yellow.

Synonyms
1,6-HEXANEDIOL
Hexane-1,6-diol
629-11-8
Hexamethylene glycol
1,6-Dihydroxyhexane
Hexamethylenediol
alpha,omega-Hexanediol
.alpha.,.omega.-Hexanediol
1,6-Hexylene Glycol
6-hydroxy-1-hexanol
DTXSID1027265
CHEBI:43078
NSC-508
ZIA319275I
1,1,6,6-D4-1,6-HEXANDIOL
27236-13-1
HEZ
CCRIS 8982
HSDB 6488
NSC 508
EINECS 211-074-0
BRN 1633461
UNII-ZIA319275I
AI3-03307
1,6hexanediol
1.6-hexanediol
1,6-hexandiol
1.6-hexandiol
.omega.-Hexanediol
1,6-hexane diol
1,6-hexan-diol
hexan-1,6-diol
Hexanediol-(1,6)
HEXANEDIOL [INCI]
1,6-Hexanediol, 97%
1,6-Hexanediol, 99%
EC 211-074-0
WLN: Q6Q
HO(CH2)6OH
SCHEMBL15343
CHEMBL458616
DTXCID907265
NSC508
1,6-HEXANEDIOL [HSDB]
HEXAMETHYLENE GLYCOL [MI]
Tox21_200450
MFCD00002985
AKOS003242194
CS-W011221
DB02210
NCGC00248624-01
NCGC00258004-01
AS-12686
BP-21412
CAS-629-11-8
FT-0607014
H0099
EN300-19325
1,6-Hexanediol, >=99% C6-Dioles basis (GC)
A834086
Q161563
J-504039
F0001-1701
Z104473540
InChI=1/C6H14O2/c7-5-3-1-2-4-6-8/h7-8H,1-6H
HEXANEDIOIC ACID
Hexanedioic acid also known as Adipic acid is a dibasic acid with the molecular formula C3H8O4, CAS 124-04-9.
Hexanedioic acid is slightly soluble in water and soluble in alcohol and acetone.
Hexanedioic acid is the most important dicarboxylic acid with roughly 2.5 billion kilograms produced annually and mainly used as a precursor to nylon production.

CAS Number: 124-04-9
EC Number: 204-673-3
Molecular Formula: C6H10O4
Molar Mass: 146.14 g/mol

Hexanedioic Acid, also known as Adipic acid, is a dicarboxylic acid.
Hexanedioic acid is an intermediate for nylon and a precursor in the synthesis of polyester polyols for polyurethane systems and thermoplastic polyurethanes.
Hexanedioic acid is colorless crystalline powder.

Hexanedioic acid is an organic dicarboxylic acid.
Available in various quantities, Hexanedioic acid is used as a monomer in nylon production.
Other applications include use as a monomer for polyurethane production, a component of controlled-release drugs, and a food additive.

Hexanedioic acid, solid white powder, is a very important organic compound for today chemical industry.
Hexanedioic acid (AA), CAS number is 124-04-9, is a dicarboxylic acid with the formula: (CH2)4(COOH)2; for the chemical point of view, 1,6 Hexanedioic acid.

The main Hexanedioic acid application is the production of nylon by a polycondensation reaction.
Nylons are produced by the reaction of bifunctional monomers containing equal parts of amine and carboxylic acid.
Besides the production of Nylon 6,6 as well as specialty nylon grades, Hexanedioic acid, CAS 124-04-9, finds many other applications, like polyester polyols for polyurethanes (PU), manufacturing of resins for paper products, unsaturated polyester resins, adipates production, plasticizers for PVC and a small share of the market is ingredient for food and medication.

90% of Hexanedioic acid is consumed in the industry for the production of nylon by poly-condensation with hexamethylenediamine.
Hexanedioic acid is mainly used for the production of nylon 6,6 polymer for fibers and plastics.

Nylon has a protein-like structure.
Hexanedioic acid can be further processed into the fibers for applications in carpets (felts), automobile tire cords and clothing.

Hexanedioic acid can be used in the production of Hexanedioic acid plasticizer and lubricant components.
Hexanedioic acid can be used in the production of polyester polyols for polyurethane systems.

Technical grade Hexanedioic acid can be used to produce plasticizers, to add flexibility and to give flexibility to unsaturated polyesters.
Hexanedioic acid can be used in the production of rigid and flexible foams, in the production of wire coaters, elastomers and adhesives, to increase the flexibility of alkyd resins, in the production of wet strong resins and in the production of synthetic lubricants and oils for the paper chemical industry.

Hexanedioic acid, mol wt 146.14, HOOCCH2CH2CH,CH2COOH, is a white crystalline solid with a melting point of about 152°C.
Little of this dicarboxylic acid occurs naturally, but Hexanedioic acid is produced on a very large scale at several locations around the world.

The majority of this material is used in the manufacture of Nylon-6,6 polyamide, which is prepared by reaction with 1,6-hexanediamine.
Hexanedioic acid is a colorless, odorless, sour-tasting crystalline solid that undergoes reactions including esterification, amidation, reduction, halogenation, salt formation, and dehydration.

Hexanedioic acid also undergoes several industrially significant polymerization reactions.
Hexanedioic acid historically has been manufactured predominantly from cyclohexane.
However, much research continues to be directed to alternative feedstocks, especially butadiene and cyclohexene, as dictated by shifts in hydrocarbon pricing.

Air quality regulations may exert further pressure for alternative routes as manufacturers seek to avoid NOx abatement costs.
When dispersed as a dust, Hexanedioic acid is subject to normal dust explosion hazards.

The material is an irritant, especially upon contact with the mucous membranes.
Protective goggles or face shields should be worn when handling the material.

The material should be stored in corrosion-resistant containers, away from alkaline or strong oxidizing materials.
Hexanedioic acid is a very large-volume organic chemical and is one of the top 50 chemicals produced in the United States in terms of volume, although demand is highly cyclic.

Hexanedioic acid for nylon takes ∼60% of U.S. cyclohexane production.
Hexanedioic acid is relatively nontoxic.

Hexanedioic acid is an important inudstrial dicarboxylic acid with about 2.5 billion kilograms produced per year.
Hexanedioic acid is used mainly in the production of nylon.
Hexanedioic acid occurs relatively rarely in nature.

Hexanedioic acid has a tart taste and is also used as an additive and gelling agent in jello or gelatins.
Hexanedioic acid is also used in some calcium carbonate antacids to make them tart.

Hexanedioic acid has also been incorporated into controlled-release formulation matrix tablets to obtain pH-independent release for both weakly basic and weakly acidic drugs.
Hexanedioic acid in the urine and in the blood is typically exogenous in origin and is a good biomarker of jello consumption.

In fact, a condition known as Hexanedioic aciduria is actually an artifact of jello consumption.
However, certain disorders (such as diabetes and glutaric aciduria type I.) can lead to elevated levels of Hexanedioic acid snd other dicarboxcylic acids (such as suberic acid) in urine.

Moreover, Hexanedioic acid is also found to be associated with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.
Hexanedioic acid is also microbial metabolite found in Escherichia.

Hexanedioic acid or hexanedioic acid is the organic compound with the formula (CH2)4(COOH)2.
From an industrial perspective, Hexanedioic acid is the most important dicarboxylic acid: about 2.5 billion kilograms of this white crystalline powder are produced annually, mainly as a precursor for the production of nylon.

Hexanedioic acid otherwise rarely occurs in nature, but Hexanedioic acid is known as manufactured E number food additive E355.
Salts and esters of Hexanedioic acid are known as adipates.

Hexanedioic acid is a white crystalline solid.
Hexanedioic acid is insoluble in water.

The primary hazard is the threat to the environment.
Immediate steps should be taken to limit Hexanedioic acid spread to the environment.
Hexanedioic acid is used to make plastics and foams and for other uses.

Hexanedioic acid is a straight-chain aliphatic dicarboxylic acid, commonly used in the manufacturing of nylon-6,6 and plasticizers.
Conventionally Hexanedioic acid was manufactured from petrochemicals but in recent days Hexanedioic acid can be synthesized from renewable substrates by means of biological methods.

Hexanedioic acid, or more formally hexanedioic acid, is a white crystalline solid that melts at 152 ºC.
Hexanedioic acid is one of the most important monomers in the polymer industry.

Hexanedioic acid is found in beet juice, but the article of commerce—≈2.5 million tonnes of Hexanedioic acid per year—is manufactured.
In 1906, French chemists L. Bouveault and R. Locquin reported that Hexanedioic acid can be produced by oxidizing cyclohexanol.
Today, the most common manufacturing process is the nitric acid (HNO3) oxidation of a cyclohexanol–cyclohexanone mixture called KA (for ketone–alcohol) oil.

Almost all Hexanedioic acid is used as a comonomer with hexamethylenediamine to produce nylon 6-6.
Hexanedioic acid is also used to manufacture other polymers such as polyurethanes.

Using HNO3 to produce Hexanedioic acid has its downside: Copious amounts of nitrous oxide (N2O), a greenhouse gas, are coproduced and released into the atmosphere.
In late 2014, K. C. Hwang and A. Sagadevan of National Tsing Hua University (Hsinchu City, Taiwan) reported a process that uses ozone and ultraviolet (UV) light to oxidize KA oil to Hexanedioic acid.

This method eliminates the production of N2O.
But before the process can be used commercially, problems associated with the formation of organic peroxides from ozone and the difficulty of using UV light on a large scale must be overcome.

Applications of Hexanedioic acid:
Hexanedioic acid is used to make nylon, polyurethane foams, lubricants, and plasticizers.
Hexanedioic acid is used in adhesives, baking powder, and food flavoring.

The major markets for Hexanedioic acid include use as feedstocks for nylon 6,6 resins and fibers, polyester polyols and plasticzers.
Documented applications for Hexanedioic acid are as a lubricant additive in coatings and foams and shoe soles, as a tanning agent in the leather industry, as a pH regulator in processes such as the manufacture of cleaning agents, as a pelletizing agent in disinfectant pills for drinking water, as an additive in flue gas sulphation, in dishwasher tablets.

Hexanedioic acid is used as an additive in coating and chemicals.
Hexanedioic acid is used as an acidulant in dry powdered food mixtures, especially in those products having delicate flavors & where addition of a tang to the flavor is undesirable.

Hexanedioic acid addition to foods imparts a smooth, tart taste.
In grape-flavored products, Hexanedioic acid adds a lingering supplementary flavor and gives an excellent set to food powders containing gelatin.

For concentrations of Hexanedioic acid ranging from 0.5-2.4 g/100 mL, the pH varies less than half a unit.
pH is low enough to inhibit browning of most fruits and other foodstuffs.

Hexanedioic acid can be used as a starting material in the preparation of:
Aliphatic polyesters by reacting with ethyleneglycol/1,3 propyleneglycol/1,4-butanediol using inorganic acid as a catalyst.
Cyclopentanone using a weak base such as Na2CO3.
Linear polybutylene adipate (PBA) having carboxylic acids at the terminals by reacting with 1,4-butanediol.

Uses of Hexanedioic acid:
More than 92% of the production of Hexanedioic acid is dedicated for the production of nylon 6,6 by a reaction with HMD Hexamethylene diamine.
Hexanedioic acid is used in nylon is utilized in fibbers, clothing, plastics, filaments, food packaging.

Hexanedioic acid is also used in polyurethane resins, foam, shoe soles, and as food additive.
Esters of Hexanedioic acid are used as plasticizers for PVC (Polyvinyl Chloride) resins and lubricant component.

Hexanedioic acid is one of the largest chemical distributor in Europe.
Hexanedioic acid is handling the storage, transport, export & import formalities of Hexanedioic acid globally.

About 60% of the 2.5 billion kg of Hexanedioic acid produced annually is used as monomer for the production of nylon by a polycondensation reaction with hexamethylene diamine forming nylon 66.
Other major applications also involve polymers; Hexanedioic acid is a monomer for production of polyurethane and Hexanedioic acid esters are plasticizers, especially in PVC.

In medicine:
Hexanedioic acid has been incorporated into controlled-release formulation matrix tablets to obtain pH-independent release for both weakly basic and weakly acidic drugs.
Hexanedioic acid has also been incorporated into the polymeric coating of hydrophilic monolithic systems to modulate the intragel pH, resulting in zero-order release of a hydrophilic drug.

The disintegration at intestinal pH of the enteric polymer shellac has been reported to improve when Hexanedioic acid was used as a pore-forming agent without affecting release in the acidic media.
Other controlled-release formulations have included Hexanedioic acid with the intention of obtaining a late-burst release profile.

In foods:
Small but significant amounts of Hexanedioic acid are used as a food ingredient as a flavorant and gelling aid.
Hexanedioic acid is used in some calcium carbonate antacids to make them tart.

As an acidulant in baking powders, Hexanedioic acid avoids the undesirable hygroscopic properties of tartaric acid.
Hexanedioic acid, rare in nature, does occur naturally in beets, but this is not an economical source for commerce compared to industrial synthesis.

Other Uses of Hexanedioic acid:
Alcoholic beverages,
Baked goods,
Condiments,
Relishes,
Fats,
Oils,
Gelatins,
Pudding,
Gravies,
Imitation dairy,
Instant coffee,
Tea,
Meat products,
Nonalcoholic beverages,
Poultry,
Snack foods,
Adhesives and Sealants,
Alkyd resins,
Beamhouse,
Carrier for fragances,
Coal,
Crop Protection,
Environment protection,
Gas desulphurization,
Hardener and crosslinking agents for polymeres,
Manufacturing of coating,
Manufacturing of dyestuffs,
Manufacturing of fibres,
Manufacturing of herbicides,
Manufacturing of pharmaceutical agents,
Manufacturing of photochemicals,
Manufacturing of plastics,
Manufacturing of tensides,
Manufacturing of textile dyestuffs,
Manufacturing of textiles dyestuffs,
Paper Manufacture,
Plasticizers for polymeres,
Polyester,
Polyester resins,
Polymer auxiliaries,
Soaking,
Synthetic lubricants,
Textile dyestuffs.

Production of Hexanedioic acid:
Hexanedioic acid is white, crystalline compound mainly obtained by oxidation of cyclohexanol and cyclohexanone with nitric acid.
An alternative method of production of Hexanedioic acid is the hydrocarbonylation of butadiene, oxidation cleavage of cyclohexene.

Manufacturing Methods of Hexanedioic acid:
Commercially important processes employ two major reaction stages.
The first reaction stage is the production of the intermediates cyclohexanone and cyclohexanol, usually abbreviated as KA, KA oil, ol-one, or anone-anol.
The KA (ketone, alcohol), after separation from unreacted cyclohexane (which is recycled) and reaction by-products, is then converted to Hexanedioic acid by oxidation with nitric acid.

Cyclohexane is produced by the oxidation of cyclohexanol or cyclohexanone with air or nitric acid.

Preparation and Reactivity of Hexanedioic acid:
Hexanedioic acid is produced from a mixture of cyclohexanone and cyclohexanol called KA oil, the abbreviation of ketone-alcohol oil.
The KA oil is oxidized with nitric acid to give Hexanedioic acid, via a multistep pathway.

Early in the reaction, the cyclohexanol is converted to the ketone, releasing nitrous acid:
HOC6H11 + HNO3 → OC(CH2)5 + HNO2 + H2O

Among Hexanedioic acid many reactions, the cyclohexanone is nitrosated, setting the stage for the scission of the C-C bond:
HNO2 + HNO3 → NO+NO3− + H2O
OC6H10 + NO+ → OC6H9-2-NO + H+

Side products of the method include glutaric and succinic acids.
Nitrous oxide is produced in about one to one mole ratio to the Hexanedioic acid, as well, via the intermediacy of a nitrolic acid.

Related processes start from cyclohexanol, which is obtained from the hydrogenation of phenol.

Alternative methods of production:
Several methods have been developed by carbonylation of butadiene.

For example, the hydrocarboxylation proceeds as follows:
CH2=CH−CH=CH2 + 2 CO + 2 H2O → HO2C(CH2)4CO2H

Another method is oxidative cleavage of cyclohexene using hydrogen peroxide.
The waste product is water.

Historically, Hexanedioic acid was prepared by oxidation of various fats, thus the name (ultimately from Latin adeps, adipis – "animal fat"; cf. adipose tissue).

Reactions:
Hexanedioic acid is a dibasic acid (Hexanedioic acid has two acidic groups).
The pKa values for their successive deprotonations are 4.41 and 5.41.

With the carboxylate groups separated by four methylene groups, Hexanedioic acid is suited for intramolecular condensation reactions.
Upon treatment with barium hydroxide at elevated temperatures, Hexanedioic acid undergoes ketonization to give cyclopentanone.

Environmental of Hexanedioic acid:
The production of Hexanedioic acid is linked to emissions of N2O, a potent greenhouse gas and cause of stratospheric ozone depletion.

At Hexanedioic acid producers DuPont and Rhodia (now Invista and Solvay, respectively), processes have been implemented to catalytically convert the nitrous oxide to innocuous products:
2 N2O → 2 N2 + O2

Adipate salts and esters:
The anionic (HO2C(CH2)4CO2−) and dianionic (−O2C(CH2)4CO2−) forms of Hexanedioic acid are referred to as adipates.
An adipate compound is a carboxylate salt or ester of the acid.

Some adipate salts are used as acidity regulators, including:
Sodium adipate (E number E356)
Potassium adipate (E357)

Some adipate esters are used as plasticizers, including:
Bis(2-ethylhexyl) adipate
Dioctyl adipate
Dimethyl adipate

Human Metabolite Information of Hexanedioic acid:

Tissue Locations:
Kidney
Liver

Handling and Storage of Hexanedioic acid:

Nonfire Spill Response:
Do not touch or walk through spilled material.
Stop leak if you can do Hexanedioic acid without risk.

Prevent dust cloud.
For Asbestos, avoid inhalation of dust.

Cover spill with plastic sheet or tarp to minimize spreading.
Do not clean up or dispose of, except under supervision of a specialist.

SMALL DRY SPILL:
With clean shovel, place material into clean, dry container and cover loosely.
Move containers from spill area.

SMALL SPILL:
Pick up with sand or other non-combustible absorbent material and place into containers for later disposal.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Cover powder spill with plastic sheet or tarp to minimize spreading.
Prevent entry into waterways, sewers, basements or confined areas.

Storage Conditions of Hexanedioic acid:

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.

Storage class (TRGS 510):
Non Combustible Solids.

Safety of Hexanedioic acid:
Hexanedioic acid, like most carboxylic acids, is a mild skin irritant.
Hexanedioic acid is mildly toxic, with a median lethal dose of 3600 mg/kg for oral ingestion by rats.

First Aid Measures of Hexanedioic acid:

General notes:
Take off contaminated clothing.

Following inhalation:
Provide fresh air.
In all cases of doubt, or when symptoms persist, seek medical advice.

Following skin contact:
Rinse skin with water/shower.
In all cases of doubt, or when symptoms persist, seek medical advice.

Following eye contact:
Irrigate copiously with clean, fresh water for at least 10 minutes, holding the eyelids apart.
In case of eye irritation consult an ophthalmologist.

Following ingestion:
Rinse mouth.
Call a doctor if you feel unwell.

INHALATION:
Remove victim to fresh air.
Get medical attention if irritation persists.

EYES:
Flush with water for at least 15 min.

SKIN:
Flush with water.

Fire Fighting of Hexanedioic acid:

SMALL FIRE:
Dry chemical, CO2, water spray or regular foam.

LARGE FIRE:
Water spray, fog or regular foam.
Do not scatter spilled material with high-pressure water streams.

If Hexanedioic acid can be done safely, move undamaged containers away from the area around the fire.
Dike runoff from fire control for later disposal.

FIRE INVOLVING TANKS:
Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

Fire Fighting Procedures of Hexanedioic acid:

Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Wear self-contained breathing apparatus for firefighting if necessary.

Stop discharge if possible, keep people away.
Shut off ignition sources.

Call fire department.
Avoid contact with solid and dust.
Isolate and remove discharged material.

If material on fire or involved in fire:
Use water in flooding quantities as fog.
Solid streams of water may spread fire.

Cool all affected containers with flooding quantities of water.
Apply water from as far a distance as possible.
Use foam, dry chemical, or carbon dioxide.

Accidental Release Measures of Hexanedioic acid:

Isolation and Evacuation:

IMMEDIATE PRECAUTIONARY MEASURE:
Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL:
Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions.
Also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Spillage Disposal of Hexanedioic acid:
Sweep spilled substance into covered plastic containers.
If appropriate, moisten first to prevent dusting.
Wash away remainder with plenty of water.

Cleanup Methods of Hexanedioic acid:

Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment.
Avoid dust formation.

Avoid breathing vapors, mist or gas.
Ensure adequate ventilation.

Evacuate personnel to safe areas.
Avoid breathing dust.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Pick up and arrange disposal without creating dust.
Sweep up and shovel.
Keep in suitable, closed containers for disposal.

Environmental considerations- land spill:
Dig a pit, pond, lagoon, or holding area to contain liquid or solid material.
If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner.
Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.

Environmental considerations- water spill:
Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom.
If dissolved, in region of 10 ppm or greater concentration, apply activated carbon at ten times the spilled amount.

Remove trapped material with suction hoses.
Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.

Electrochemical measurements have been made on the system Cu(2+), Hexanedioic acid, nitric acid (which models the effluent from Hexanedioic acid plants) to investigate the reasons for the observed low current efficiency for copper deposition from such soln.
The most probable cause is a cathodic shift in the deposition potential of copper making the reduction of NO3- the preferred process.

Depletion experiments have been carried out on real effluent in two three-dimensional cells, a bipolar trickle tower and a porous reticulated carbon bed.
Each performs reasonably well and, while the current efficiencies are low (about 20%), the deposition is essentially mass-transfer controlled.

Neutralizing agents for acids and caustics:
Rinse with dilute soda ash solution.

Identifiers of Hexanedioic acid:
CAS Number: 124-04-9
Beilstein Reference: 1209788
ChEBI: CHEBI:30832
ChEMBL: ChEMBL1157
ChemSpider: 191
ECHA InfoCard: 100.004.250
EC Number: 204-673-3
E number: E355 (antioxidants, ...)
Gmelin Reference: 3166
KEGG: D08839
PubChem CID: 196
RTECS number: AU8400000
UNII: 76A0JE0FKJ
UN number: 3077
CompTox Dashboard (EPA): DTXSID7021605

InChI:
InChI=1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)
Key: WNLRTRBMVRJNCN-UHFFFAOYSA-N
InChI=1/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)
Key: WNLRTRBMVRJNCN-UHFFFAOYAY

SMILES:
O=C(O)CCCCC(=O)O
C(CCC(=O)O)CC(=O)O

CAS number: 124-04-9
EC index number: 607-144-00-9
EC number: 204-673-3
Hill Formula: C₆H₁₀O₄
Molar Mass: 146.14 g/mol
HS Code: 2917 12 00

CAS Number: 124-04-9
Molecular Weight: 146.14
Beilstein: 1209788
EC Number: 204-673-3
MDL number: MFCD00004420
eCl@ss: 39021711
PubChem Substance ID: 57653836
NACRES: NA.21

CAS: 124-04-9
Molecular Formula: C6H10O4
Molecular Weight (g/mol): 146.142
MDL Number: MFCD00004420
InChI Key: WNLRTRBMVRJNCN-UHFFFAOYSA-N
PubChem CID: 196
ChEBI: CHEBI:30832
IUPAC Name: hexanedioic acid
SMILES: C(CCC(=O)O)CC(=O)O

Properties of Hexanedioic acid:
Chemical formula: C6H10O4
Molar mass: 146.142 g·mol−1
Appearance: White crystals[1]
Monoclinic prisms[2]
Odor: Odorless
Density: 1.360 g/cm3
Melting point: 152.1 °C (305.8 °F; 425.2 K)
Boiling point: 337.5 °C (639.5 °F; 610.6 K)
Solubility in water: 14 g/L (10 °C)
24 g/L (25 °C)
1600 g/L (100 °C)
Solubility: Very soluble in methanol, ethanol
soluble in acetone, acetic acid
slightly soluble in cyclohexane
negligible in benzene, petroleum ether
log P: 0.08
Vapor pressure: 0.097 hPa (18.5 °C) = 0.073 mmHg
Acidity (pKa): 4.43, 5.41
Conjugate base: Adipate
Viscosity: 4.54 cP (160 °C)

Density: 1.36 g/cm3 (25 °C)
Flash point: 196 °C
Ignition temperature: 405 °C
Melting Point: 150.85 °C
pH value: 2.7 (23 g/l, H₂O, 25 °C)
Vapor pressure: 0.097 hPa (18.5 °C)
Bulk density: 700 kg/m3
Solubility: 15 g/l

General Properties: White, solid crystals
Odor: Odorless
Intensity: 1.360 g/cm3
Boiling point: 337,5°C
Melting point: 152,1 °C
Flash point: 196°C
Vapor pressure: 0,0073 mmHg (18,5 °C)
Refraction index: –
Solubility (aquenous): 14g/L (10°C), 1600 g/L (100°C)

Vapor density: 5 (vs air)
Quality Level: 200
Vapor pressure: 1 mmHg ( 159.5 °C)
Assay: 99%
Form: crystals
Autoignition temp.: 788 °F
bp: 265 °C/100 mmHg (lit.)
mp: 151-154 °C (lit.)
Solubility: H2O: soluble 23 g/L at 25 °C
SMILES string: OC(=O)CCCCC(O)=O
InChI: 1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)
InChI key: WNLRTRBMVRJNCN-UHFFFAOYSA-N

Molecular Weight: 146.14
XLogP3: 0.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 5
Exact Mass: 146.05790880
Monoisotopic Mass: 146.05790880
Topological Polar Surface Area: 74.6 Ų
Heavy Atom Count: 10
Complexity: 114
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Hexanedioic acid:
Assay (acidimetric): ≥ 99.0 %
Melting range (lower value): ≥ 150 °C
Melting range (upper value): ≤ 154 °C
Identity (IR): passes test

Melting Point: 151.0°C to 153.0°C
Boiling Point: 337.0°C
CAS Min %: 98.5
CAS Max %: 100.0
Color: White
Assay Percent Range: 99%
Linear Formula: HO2C(CH2)4CO2H
Beilstein: 02, 649
Fieser: 01,15
Merck Index: 15, 150
Formula Weight: 146.14
Percent Purity: 99%
Quantity: 500 g
Flash Point: 196°C
Infrared Spectrum: Authentic
Packaging: Plastic bottle
Physical Form: Crystalline Powder
Chemical Name or Material: Hexanedioic acid

Structure of Hexanedioic acid:
Crystal structure: Monoclinic

Thermochemistry of Hexanedioic acid:
Std enthalpy of formation (ΔfH⦵298): −994.3 kJ/mol[3

Related Products of Hexanedioic acid:
Hydroxynorketamine-d6 Hydrochloride
(S)-Ketamine-d6 Hydrochloride
Norketamine-d4
S-(-)-Norketamine-d6 Hydrochloride
Phencyclidine-d5 Hydrochloride

Related compounds of Hexanedioic acid:

Related dicarboxylic acids:
glutaric acid
pimelic acid

Related compounds:
hexanoic acid
adipic acid dihydrazide
hexanedioyl dichloride
hexanedinitrile
hexanediamide

Names of Hexanedioic acid:

Preferred IUPAC name:
Hexanedioic acid

Other names:
Adipic acid
Butane-1,4-dicarboxylic acid
Hexane-1,6-dioic acid
1,4-butanedicarboxylic acid

Synonyms of Hexanedioic acid:
adipic acid
hexanedioic acid
124-04-9
Adipinic acid
1,4-Butanedicarboxylic acid
Adilactetten
Acifloctin
Acinetten
1,6-Hexanedioic acid
Molten adipic acid
Kyselina adipova
Adipinsaure [German]
Acide adipique [French]
FEMA No. 2011
Kyselina adipova [Czech]
Hexanedioate
Adipinsaeure
adipic-acid
Adipidic acid
Adi-pure
NSC 7622
Adipic acid [NF]
NSC-7622
Hexan-1,6-dicarboxylate
76A0JE0FKJ
Hexanedioc acid
INS NO.355
1,6-HEXANE-DIOIC ACID
E-355
CHEBI:30832
INS-355
NSC7622
Adipic acid (NF)
NCGC00091345-01
E355
hexane-1,6-dioic acid
Adipinsaure
Acide adipique
FEMA Number 2011
CAS-124-04-9
CCRIS 812
HSDB 188
EINECS 204-673-3
MFCD00004420
UNII-76A0JE0FKJ
BRN 1209788
Adipinate
Molten adipate
AI3-03700
hexane dioic acid
1,6-Hexanedioate
0L1
Adipic acid, 99%
Neopentyl Glycol Flake
Adipic acid-[13C6]
1, 6-Hexanedioic Acid
Adipic acid, >=99%
ADIPIC ACID [II]
ADIPIC ACID [MI]
WLN: QV4VQ
ADIPIC ACID [FCC]
bmse000424
EC 204-673-3
ADIPIC ACID [FHFI]
ADIPIC ACID [HSDB]
ADIPIC ACID [INCI]
SCHEMBL4930
CHEMBL1157
NCIOpen2_001004
NCIOpen2_001222
HOOC-(CH2)4-COOH
ADIPIC ACID [MART.]
Adipic acid, >=99.5%
4-02-00-01956 (Beilstein Handbook Reference)
ADIPIC ACID [USP-RS]
ADIPIC ACID [WHO-DD]
BIDD:ER0342
INS No. 355
DTXSID7021605
Adipic acid, puriss., 99.8%
Pharmakon1600-01301012
ADIPIC ACID [EP MONOGRAPH]
ZINC1530348
Tox21_111118
Tox21_202161
Tox21_300344
BBL011615
LMFA01170048
NSC760121
s3594
STL163338
AKOS000119031
Tox21_111118_1
CCG-230896
CS-W018238
HY-W017522
NSC-760121
NCGC00091345-02
NCGC00091345-03
NCGC00091345-04
NCGC00091345-05
NCGC00254389-01
NCGC00259710-01
AC-10343
BP-21150
BP-30248
Hexanedioic Acid, Butanedicarboxylic Acid
A0161
Adipic acid, BioXtra, >=99.5% (HPLC)
Adipic acid, SAJ special grade, >=99.5%
E 355
FT-0606810
EN300-18041
Adipic acid, Vetec(TM) reagent grade, >=99%
C06104
D08839
D70505
AB00988898-01
AB00988898-03
Q357415
SR-01000944270
J-005034
J-519542
SR-01000944270-2
Z57127533
Adipic acid, certified reference material, TraceCERT(R)
F0001-0377
Adipic acid, European Pharmacopoeia (EP) Reference Standard
1F1316F2-7A32-4339-8C2A-8CAA84696C95
Adipic acid, United States Pharmacopeia (USP) Reference Standard
124-04-9 [RN]
204-673-3 [EINECS]
Acide adipique [French] [ACD/IUPAC Name]
Adipic acid [ACD/IUPAC Name] [Wiki]
Adipinsäure [German] [ACD/IUPAC Name]
Asapic
Hexanedioic acid [ACD/Index Name]
Inipol DS
kwas adypinowy [Polish]
kyselina adipová [Czech]
MFCD00004420 [MDL number]
1,4-butanedicarboxylic acid
1,6-HEXANEDIOIC ACID
1,6-HEXANE-DIOIC ACID
121311-78-2 [RN]
19031-55-1 [RN]
2-Oxoadipic acid
52089-65-3 [RN]
Acifloctin
Acinetten
Adilactetten
Adipic Acid FCC
adipicacid
adipinic acid
Butane-1,4-dicarboxylic acid
BUTANEDICARBOXYLIC ACID
Hexanedioic-3,3,4,4-d4 Acid
hydron [Wiki]
QV4VQ [WLN]
HEXANOIC ACID, 2-ETHYL- (2-ETHYLHEXANOIC ACID)
DESCRIPTION:
Hexanoic acid, 2-ethyl-, also known as 2-ethylhexanoic acid or 2-EHA, is an industrial chemical.
A major use of Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is in the preparation of metal salts and soaps used as drying agents in paint and inks, and as thermal stabilizers in polyvinyl chloride (PVC).
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is also used in the manufacture of resins used in automobile windshields and vinyl flooring.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is not manufactured in Canada, but it is imported into Canada.

CAS:149-57-5
European Community (EC) Number: 205-743-6
Molecular Formula: C8H16O2


2-Ethylhexanoic acid, also known as 2-ethylhexanoate or alpha-ethylcaproic acid, belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is a very hydrophobic molecule, practically insoluble in water, and relatively neutral. 2-Ethylhexanoic acid is a potentially toxic compound.


Ethylhexoic acid is a colorless to light yellow liquid with a mild odor.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) will burn though it may take some effort to ignite.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is slightly soluble in water.

Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is corrosive to metals and tissue.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is used to make paint dryers and plasticizers.

Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is a branched-chain fatty acid.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is a natural product found in Vitis vinifera and Artemisia arborescens with data available


Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is the organic compound with the formula CH3(CH2)3CH(C2H5)CO2H.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is a carboxylic acid that is widely used to prepare lipophilic metal derivatives that are soluble in nonpolar organic solvents.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is a colorless viscous oil.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is supplied as a racemic mixture.


PRODUCTION OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is produced industrially from propylene, which is hydroformylated to give butyraldehyde.
Aldol condensation of the aldehyde gives 2-ethylhexenal, which is hydrogenated to 2-ethylhexanal.
Oxidation of this aldehyde gives the carboxylic acid.


Metal ethylhexanoates:
65% Solution of cobalt(II) bis(2-ethylhexanoate) in mineral spirits, tilted vial to illustrate color and viscosity.
2-Ethylhexanoic acid forms compounds with metal cations that have stoichiometry as metal acetates.
These ethylhexanoate complexes are used in organic and industrial chemical synthesis.

They function as catalysts in polymerizations as well as for oxidation reactions as "oil drying agents."
They are highly soluble in nonpolar solvents.
These metal complexes are often described as salts. They are, however, not ionic but charge-neutral coordination complexes.
Their structures are akin to the corresponding acetates.



APPLICATIONS OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):

2-Ethylhexanoic Acid (2-EHA) is one of the flagship products within Perstorp Group which has the largest production capacity in the world.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is a colorless liquid with one carboxylic group based on a C8 carbon chain.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is widely used in esters for PVB film plasticizers and synthetic lubricants, in production of metal soaps for paint driers, in automotive coolants and PVC stabilizers.

Other application areas include wood preservatives, catalyst for polyurethane and in pharmaceuticals.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is generally used to produce metal derivatives which are dissolved in nonpolar organic solvents.
2-Ethylhexanoic acid (EHXA, 2-EHA) is an industrially important aliphatic carboxylic acid.

Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is widely employed as a stabilizer and a wood preservative.

Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) has various industrial applications, such as:
• coolant in automotives
• synthetic lubricant
• wetting agent
• co-solvent
• drying of paints
• defoaming agent in pesticides


2-Ethylhexanoic acid (2-EHA) is a versatile monocarboxylic acid chemical intermediate.
Automotive:
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is used in the production of corrosion inhibitors for automotive coolants.

Coatings:
This monomer is used in the synthesis of alkyd resins provides improved yellowing resistanct than the standard fatty acids.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is particularly suitable for stoving enamels and two-component coatings.
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is also used as a raw material for metal based paint driers.

Lubricants :
Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is a major raw material for polyolesters used in synthetic lubricants.

Personal Care:
In cosmetics, Hexanoic acid, 2-ethyl-(2-ethylhexanoic acid) is used to produce emollients.

Other :
The production of polyvinylbutyral (PVB) plasticizers and polyvinylchloride (PVC) stabilizers in the form of metal salts.
Other applications include, catalyst for polymer production, raw material for acid chloride and fragrances.




SAFETY INFORMATION ABOUT HEXANOIC ACID, 2-ETHYL- (2-ETHYLHEXANOIC ACID):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product






CHEMICAL AND PHYSICAL PROPERTIES OF HEXANOIC ACID, 2-ETHYL- (2-ETHYLHEXANOIC ACID):
Molecular Weight
144.21 g/mol
XLogP3
2.6
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
5
Exact Mass
144.115029749 g/mol
Monoisotopic Mass
144.115029749 g/mol
Topological Polar Surface Area
37.3Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
99.4
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Chemical formula, C8H16O2
Molar mass, 144.214 g•mol−1
Appearance, Colorless liquid
Density, 903 mg mL−1
Melting point, −59.00 °C; −74.20 °F; 214.15 K
Boiling point, 228.1 °C; 442.5 °F; 501.2 K
log P, 2.579
Vapor pressure, Acidity (pKa), 4.819
Basicity (pKb), 9.178
Refractive index (nD), 1.425
Thermochemistry,
Std enthalpy of formation (ΔfH⦵298), −635.1 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298), -4.8013–4.7979 MJ mol−1
CAS number, 149-57-5
EC index number, 607-230-00-6
EC number, 205-743-6
Hill Formula, C₈H₁₆O₂
Molar Mass, 144.21 g/mol
HS Code, 2915 90 70
Boiling point, 226 - 229 °C (1013 hPa)
Density, 0.91 g/cm3 (20 °C)
Explosion limit, 0.9 - 6.7 %(V)
Flash point, 114 °C
Ignition temperature, 310 °C
Melting Point, -59 °C
pH value, 3 (1.4 g/l, H₂O, 20 °C)
Vapor pressure, Solubility, 1.4 g/l


SYNONYMS OF HEXANOIC ACID, 2-ETHYL- (2-ETHYLHEXANOIC ACID):
2-ETHYLHEXANOIC ACID
149-57-5
2-Ethylcaproic acid
Hexanoic acid, 2-ethyl-
Ethylhexanoic acid
Ethylhexoic acid
2-Ethylhexoic acid
Butylethylacetic acid
2-Butylbutanoic acid
3-Heptanecarboxylic acid
Ethyl hexanoic acid
2-ethyl-hexoic acid
2-ethyl hexanoic acid
alpha-Ethylcaproic acid
2-ethyl-hexanoic acid
Ethyl hexanoic acid, 2-
alpha-ethyl caproic acid
.alpha.-Ethylcaproic acid
2-Ethyl-1-hexanoic acid
01MU2J7VVZ
2-ETHYL HEXOIC ACID,AR
61788-37-2
DTXSID9025293
CHEBI:89058
NSC-8881
2-ethylhexanoicacid
2-Ethylhexansaeure
DTXCID805293
2-Ethylhexanoic acid, >=99%
2-Ethylhexanoic acid, analytical standard
CAS-149-57-5
2 ETHYL HEXANOIC ACID
CCRIS 3348
HSDB 5649
Kyselina 2-ethylkapronova [Czech]
NSC 8881
Kyselina 2-ethylkapronova
EINECS 205-743-6
(+/-)-2-ETHYLHEXANOIC ACID
UNII-01MU2J7VVZ
Kyselina heptan-3-karboxylova [Czech]
BRN 1750468
Kyselina heptan-3-karboxylova
AI3-01371
Hexanoic acid, 2-ethyl-, (-)-
EINECS 262-971-9
MFCD00002675
2-Ethylcapronic acid
2-Ethyl-Hexonic acid
alpha-Ethylhexanoic acid
.alpha.-Ethylhexanoic acid
EC 205-743-6
SCHEMBL25800
2-Ethylhexanoic acid, 99%
MLS002415695
CHEMBL1162485
WLN: QVY4 & 2
NSC8881
HMS2267F21
STR05759
2-ETHYLHEXANOIC ACID [HSDB]
Tox21_201406
Tox21_300108
LMFA01020087
AKOS009031416
AT29893
CS-W016381
SB44987
SB44994
Hexanoic acid,2-ethyl-, tridecyl ester
NCGC00091324-01
NCGC00091324-02
NCGC00091324-03
NCGC00253985-01
NCGC00258957-01
SMR001252268
E0120
FT-0612273
FT-0654390
EN300-20410
Q209384
W-109079
F0001-0703
Z104478072
18FEB650-7573-4EA0-B0CD-9D8BED766547
2-Ethylhexanoic acid, Pharmaceutical Secondary Standard; Certified Reference Material

HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID)
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is the organic compound with the formula CH3(CH2)3CH(C2H5)CO2H.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a carboxylic acid that is widely used to prepare lipophilic metal derivatives that are soluble in nonpolar organic solvents.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colorless to light yellow liquid with a mild odor.


CAS Number: 149-57-5
72377-05-0 S enantiomer
56006-48-5 R enantiomer
EC Number: 205-743-6
MDL number: MFCD00002675
Molecular Formula: C8H16O2 / CH3(CH2)3CH(C2H5)COOH
Chemical formula: C8H16O2



2-ETHYLHEXANOIC ACID, 149-57-5, 2-Ethylcaproic acid, Hexanoic acid, 2-ethyl-, Ethylhexanoic acid, Ethylhexoic acid, 2-Ethylhexoic acid, Butylethylacetic acid, 2-Butylbutanoic acid, 3-Heptanecarboxylic acid, Ethyl hexanoic acid, 2-ethyl-hexoic acid, 2-ethyl hexanoic acid, alpha-Ethylcaproic acid, 2-ethyl-hexanoic acid, Ethyl hexanoic acid, 2-, alpha-ethyl caproic acid, .alpha.-Ethylcaproic acid, 2-Ethyl-1-hexanoic acid, 61788-37-2, 01MU2J7VVZ, 2-EHA,
2-ETHYL HEXOIC ACID,AR, DTXSID9025293, CHEBI:89058, NSC-8881, MFCD00002675, 2-ethylhexanoicacid, 2-Ethylhexansaeure, DTXCID805293, 2-Ethylhexanoic acid, >=99%, 2-Ethylhexanoic acid, analytical standard, CAS-149-57-5, 2 ETHYL HEXANOIC ACID, CCRIS 3348, HSDB 5649, NSC 8881, Kyselina 2-ethylkapronova,
EINECS 205-743-6, (+/-)-2-ETHYLHEXANOIC ACID, UNII-01MU2J7VVZ, α-Ethylcaproic acid, α-Ethylhexanoic acid, Butylethylacetic acid, Ethylhexanoic acid, Ethylhexoic acid, 2-Butylbutanoic acid, 2-Ethylcaproic acid, 2-Ethylhexanoic acid, 2-Ethylhexoic acid, 3-Heptanecarboxylic acid, Kyselina 2-ethylkapronova, Kyselina heptan-3-karboxylova, 2-Ethyl-1-hexanoic acid, 2-Ethylcapronic acid, NSC 8881, 2-ethylhexyl 2-ethylhexanoate, ETHYLHEXYL ETHYLHEXANOATE, 2-Ethylhexyl-2-ethylhexanoat, 2-Ethylhexanoic acid, 2-ethylhexyl ester, Dragoxate EH, Hexanoic acid, 2-ethyl-, 2-ethylhexyl ester, DRAGOXAT EH, Hexanoic acid,2-ethyl-, Caproic acid,α-ethyl-, 2-Ethylhexanoic acid, Butylethylacetic acid, α-Ethylcaproic acid, 2-Ethylhexoic acid, 3-Heptanecarboxylic acid, 2-Ethylcaproic acid, Ethylhexanoic acid, α-Ethylhexanoic acid, 2-Butylbutanoic acid, 2-Ethyl-1-hexanoic acid, (±)-2-Ethylhexanoic acid, NSC 8881, Octylic acid, 83829-68-9, 202054-39-5 Hexanoic acid, 2-ethyl-, Ethylhexanoic acid, 2-ETHYLCAPROIC ACID, 2-ethylhexanoic, 2-Ethyl-1-hexanoic acid, Ethylhexoic acid, CAPRYLIC ACID(SG), 2-ETHYLCAPRONIC ACID, (RS)-2-Ethylhexansαure, 2-Ethylhexanoic acid, BRN 1750468, Kyselina heptan-3-karboxylova, AI3-01371, Hexanoic acid, 2-ethyl-, (-)-, EINECS 262-971-9, 2-Ethylcapronic acid, 2-Ethyl-Hexonic acid, alpha-Ethylhexanoic acid, .alpha.-Ethylhexanoic acid, EC 205-743-6, SCHEMBL25800, 2-Ethylhexanoic acid, 99%, MLS002415695, CHEMBL1162485, WLN: QVY4 & 2, NSC8881, HMS2267F21, STR05759, 2-ETHYLHEXANOIC ACID [HSDB],
Tox21_201406, Tox21_300108, LMFA01020087, AKOS009031416, AT29893, CS-W016381, SB44987, SB44994, Hexanoic acid,2-ethyl-, tridecyl ester, NCGC00091324-01, NCGC00091324-02, NCGC00091324-03, NCGC00253985-01, NCGC00258957-01, SMR001252268, E0120, FT-0612273, FT-0654390, NS00010660, EN300-20410, Q209384, W-109079,
F0001-0703, Z104478072, 18FEB650-7573-4EA0-B0CD-9D8BED766547, 2-Ethylhexanoic acid, Pharmaceutical Secondary Standard; Certified Reference Material,



Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colorless viscous oil.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is supplied as a racemic mixture.
Other applications of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) include, catalyst for polymer production, raw material for acid chloride and fragrances.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colorless to light yellow liquid with a mild odor.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) will burn though it may take some effort to ignite.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is slightly soluble in water.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is corrosive to metals and tissue.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colorless to light yellow liquid with a mild odor.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) will burn though 2-Ethylhexanoic acid may take some effort to ignite.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is slightly soluble in water.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is corrosive to metals and tissue.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is the organic compound with the formula CH3(CH2)3CH(C2H5)CO2H.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a carboxylic acid that is widely used to prepare lipophilic metal derivatives that are soluble in nonpolar organic solvents.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colorless to light yellow liquid with a mild odor.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colorless, high boiling liquid having a mild odor.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colourless liquid.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a branched-chain fatty acid.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid), also known as 2-ethylhexanoic acid or 2-EHA, is an industrial chemical.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colorless to light yellow liquid with a mild odor.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) will burn though it may take some effort to ignite. It is slightly soluble in water.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is corrosive to metals and tissue.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a branched-chain fatty acid.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a natural product found in Vitis vinifera and Artemisia arborescens with data available.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is found in fruits.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is found in grapes.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) belongs to the family of Branched Fatty Acids.
These are fatty acids containing a branched chain.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colorless to light yellow liquid with a mild odor.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) will burn though it may take some effort to ignite.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is slightly soluble in water.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is corrosive to metals and tissue.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a branched-chain fatty acid.



USES and APPLICATIONS of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used in the production of corrosion inhibitors for automotive coolants.
Lubricants uses of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid): Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a major raw material for polyolesters used in synthetic lubricants.


Personal Care uses of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid): In cosmetics, Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used to produce emollients.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used to make paint dryers and plasticizers.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used in the preparation of metal derivatives, which act as a catalyst in polymerization reactions.
For example, tin 2-ethylhexanoate is used in the manufacturing of poly(lactic-co-glycolic acid).
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is also used as a stabilizer for polyvinyl chlorides.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is also involved in solvent extraction and dye granulation.
Further, Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used to prepare plasticizers, lubricants, detergents, flotation aids, corrosion inhibitors and alkyd resins.


In addition to this, Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) serves as a catalyst for polyurethane foaming.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used as a reactant in esterification , decarboxylative alkynylation , and preparation of alkyl coumarins via decarboxylative coupling reactions.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used in the organocatalytic medium for the preparation of various 3,4-dihydropyrimidin-2(1H)-ones/thiones by Biginelli reaction.
PHexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used paint and varnish driers (metallic salts).


Ethylhexoates of light metals are used to convert some mineral oils to greases.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid)'s esters are used as plasticizers.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used to make paint dryers and plasticizers.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used in the following products: anti-freeze products, laboratory chemicals and metal working fluids.


Other release to the environment of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is likely to occur from: indoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used in the following products: coating products.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used to make paint dryers and plasticizers.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used in the following areas: scientific research and development.


Release to the environment of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) can occur from industrial use: formulation of mixtures.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used in the following products: coating products, laboratory chemicals, lubricants and greases and metal working fluids.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.


Release to the environment of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) can occur from industrial use: manufacturing of the substance.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used to make paint dryers and plasticizers.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a colorless to light yellow liquid with a mild odor.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) will burn though it may take some effort to ignite.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is slightly soluble in water.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is corrosive to metals and tissue.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used to make paint dryers and plasticizers.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used Auto OEM


Cosmetic and personal care intermediate, Paints & coatings, and Pharmaceutical chemicals.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used the production of polyvinylbutyral (PVB) plasticizers and polyvinylchloride (PVC) stabilizers in the form of metal salts.


-Coatings uses of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid):
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is used in the synthesis of alkyd resins provides improved yellowing resistanct than the standard fatty acids.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is particularly suitable for stoving enamels and two-component coatings.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is also used as a raw material for metal based paint driers.



ALTERNATIVE PARENTS OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
*Branched fatty acids
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
*Medium-chain fatty acid
*Branched fatty acid
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound



PREPARATION OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
In a dry 1L three-neck bottle, Add isooctyl aldehyde (80g, 0.62mol) And the solvent Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (240g, 1.66mol), ligand L8 (5.24mg, 0.007mmol), cesium carbonate (18.24mg, 0.056mmol), potassium acetate 160mg, placed in a water bath, mechanical under nitrogen atmosphere Stir, after the temperature rises to 30 ° C, Air flow was started at a flow rate of 11.9 g/h, and the reaction temperature was maintained at 30-35 ° C by adding cooling water to the water bath.
After 6 hours of reaction, the conversion of isooctyl aldehyde was calculated to be 99.6%.
The selectivity of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) was 99.5%, and the yield was 99.10%.



HOW IS HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) USED?
A major use of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is in the preparation of metal salts and soaps used as drying agents in paint and inks, and as thermal stabilizers in polyvinyl chloride (PVC).
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is also used in the manufacture of resins used in automobile windshields and vinyl flooring.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is not manufactured in Canada, but it is imported into Canada.



PRODUCTION OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is produced industrially from propylene, which is hydroformylated to give butyraldehyde.
Aldol condensation of the aldehyde gives 2-ethylhexenal, which is hydrogenated to 2-ethylhexanal.
Oxidation of this aldehyde gives the carboxylic acid.

Metal ethylhexanoates:
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) forms compounds with metal cations that have stoichiometry as metal acetates.
These ethylhexanoate complexes are used in organic and industrial chemical synthesis.

They function as catalysts in polymerizations as well as for oxidation reactions as "oil drying agents."
They are highly soluble in nonpolar solvents.
These metal complexes are often described as salts.

They are, however, not ionic but charge-neutral coordination complexes.
Their structures are akin to the corresponding acetates.

Examples of metal ethylhexanoates:
Hydroxyl aluminium bis(2-ethylhexanoate), used as a thickener
Tin(II) ethylhexanoate (CAS# 301-10-0), a catalyst for polylactide and poly(lactic-co-glycolic acid).
Cobalt(II) ethylhexanoate (CAS# 136-52-7), a drier for alkyd resins
Nickel(II) ethylhexanoate (CAS# 4454-16-4)



REACTIVITY PROFILE OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) is a carboxylic acid.
Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.

Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water.

Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions.
The pH of solutions of carboxylic acids is therefore less than 7.0.
Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt.

Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.
Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) to corrode or dissolve iron, steel, and aluminum parts and containers.

Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.
The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.

Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides.
Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat.

Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat.
Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents.
These reactions generate heat.

A wide variety of products is possible.
Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.



PHYSICAL and CHEMICAL PROPERTIES of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
Chemical formula: C8H16O2
Molar mass: 144.214 g·mol−1
Appearance: Colorless liquid
Density: 903 mg mL−1
Melting point: −59.00 °C; −74.20 °F; 214.15 K
Boiling point: 228.1 °C; 442.5 °F; 501.2 K
log P: 2.579
Vapor pressure: Acidity (pKa): 4.819
Basicity (pKb): 9.178
Refractive index (nD): 1.425
Std enthalpy of formation (ΔfH⦵298): −635.1 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): -4.8013–4.7979 MJ mol−1
Appearance: colorless clear liquid (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.89300 to 0.91300 @ 25.00 °C.
Pounds per Gallon - (est).: 7.431 to 7.597

Refractive Index: 1.42000 to 1.42600 @ 20.00 °C.
Melting Point: -59.00 °C. @ 760.00 mm Hg
Boiling Point: 220.00 to 223.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.030000 mmHg @ 20.00 °C.
Vapor Density: 4.98 ( Air = 1 )
Flash Point: 244.00 °F. TCC ( 117.78 °C. )
logP (o/w): 2.640
Soluble in: alcohol, water, 2000 mg/L @ 20 °C (exp)
Insoluble in: water
Molecular Weight: 144.21 g/mol
XLogP3: 2.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 5
Exact Mass: 144.115029749 g/mol
Monoisotopic Mass: 144.115029749 g/mol
Topological Polar Surface Area: 37.3Ų

Heavy Atom Count: 10
Formal Charge: 0
Complexity: 99.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Water Solubility: 2.07 g/L
logP: 2.61
logP: 2.8
logS: -1.8
pKa (Strongest Acidic): 5.14
Physiological Charge: -1
Hydrogen Acceptor Count: 2

Hydrogen Donor Count: 1
Polar Surface Area: 37.3 Ų
Rotatable Bond Count: 5
Refractivity: 40.25 m³·mol⁻¹
Polarizability: 16.99 ų
Number of Rings: 0
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule: No
Physical state: clear, liquid
Color: colorless
Odor: No data available
Melting point/freezing point:
Melting point/range: -59 °C

Initial boiling point and boiling range: 228 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 6,7 %(V)
Lower explosion limit: 0,9 %(V)
Flash point: 114 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 3 at 1,4 g/l at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: log Pow: 2,7 at 25 °C
Vapor pressure 13 hPa at 115 °C: < 0,01 hPa at 20 °C

Density: 0,903 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapo density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Relative vapor density: 4,98 - (Air = 1.0)
Chemical formula: C8H16O2
Molar mass: 144.214 g·mol−1
Appearance: Colorless liquid
Density: 903 mg mL−1
Melting point: −59.00 °C; −74.20 °F; 214.15 K
Boiling point: 228.1 °C; 442.5 °F; 501.2 K

log P: 2.579
Vapor pressure: Acidity (pKa): 4.819
Basicity (pKb): 9.178
Refractive index (nD) 1.425
Melting point: -59 °C
Boiling point: 228 °C(lit.)
Density: 0.906
vapor density: 4.98 (vs air)
vapor pressure: refractive index: n20/D 1.425(lit.)
Flash point: 230 °F
storage temp.: Store below +30°C.
solubility: 1.4g/l
form: Liquid

pka: pK1:4.895 (25°C)
color: Clear
PH: 3 (1.4g/l, H2O, 20℃)
Odor: Mild odour
PH Range: 3 at 1.4 g/l at 20 °C
Viscosity: 7.73 cps
explosive limit: 1.04%, 135°F
Water Solubility: 2 g/L (20 ºC)
BRN: 1750468
Exposure limits ACGIH: TWA 5 mg/m3
Stability: Stable.
Incompatible with strong oxidizing agents, reducing agents, bases.
InChIKey: OBETXYAYXDNJHR-UHFFFAOYSA-N
LogP: 2.7 at 25℃
CAS DataBase Reference: 149-57-5(CAS DataBase Reference)
EWG's Food Scores: 2

FDA UNII: 01MU2J7VVZ
NIST Chemistry Reference: Hexanoic acid, 2-ethyl-(149-57-5)
EPA Substance Registry System: 2-Ethylhexanoic acid (149-57-5)
Molecular Weight:293.40
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:293.22022309
Monoisotopic Mass:293.22022309
Topological Polar Surface Area:101
Heavy Atom Count:20
Complexity:155
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes




FIRST AID MEASURES of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent and neutralising material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water
system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Viton
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 240 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA)
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a branched-chain fatty acid.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a natural product found in Vitis vinifera and Artemisia arborescens with data available.


CAS Number: 149-57-5
72377-05-0 S enantiomer
56006-48-5 R enantiomer
EC Number: 205-743-6
MDL number: MFCD00002675
Molecular Formula: C8H16O2 / CH3(CH2)3CH(C2H5)COOH
Chemical formula: C8H16O2



SYNONYMS:
Hexanoic acid,2-ethyl-, Caproic acid,α-ethyl-, 2-Ethylhexanoic acid, Butylethylacetic acid, α-Ethylcaproic acid, 2-Ethylhexoic acid, 3-Heptanecarboxylic acid, 2-Ethylcaproic acid, Ethylhexanoic acid, α-Ethylhexanoic acid, 2-Butylbutanoic acid, 2-Ethyl-1-hexanoic acid, (±)-2-Ethylhexanoic acid, NSC 8881, Octylic acid, 83829-68-9, 202054-39-5, α-Ethylcaproic acid, α-Ethylhexanoic acid, Butylethylacetic acid, Ethylhexanoic acid, Ethylhexoic acid, 2-Butylbutanoic acid, 2-Ethylcaproic acid, 2-Ethylhexanoic acid, 2-Ethylhexoic acid, 3-Heptanecarboxylic acid, Kyselina 2-ethylkapronova, Kyselina heptan-3-karboxylova, 2-Ethyl-1-hexanoic acid, 2-Ethylcapronic acid, NSC 8881, 2-ETHYLHEXANOIC ACID, 149-57-5, 2-Ethylcaproic acid, Hexanoic acid, 2-ethyl-, Ethylhexanoic acid, Ethylhexoic acid, 2-Ethylhexoic acid, Butylethylacetic acid, 2-Butylbutanoic acid, 3-Heptanecarboxylic acid, Ethyl hexanoic acid, 2-ethyl-hexoic acid, 2-ethyl hexanoic acid, alpha-Ethylcaproic acid, 2-ethyl-hexanoic acid, Ethyl hexanoic acid, 2-, alpha-ethyl caproic acid, .alpha.-Ethylcaproic acid, 2-Ethyl-1-hexanoic acid, 61788-37-2, 01MU2J7VVZ, 2-EHA, 2-ETHYL HEXOIC ACID,AR, DTXSID9025293, CHEBI:89058, NSC-8881, MFCD00002675, 2-ethylhexanoicacid, 2-Ethylhexansaeure, DTXCID805293, 2-Ethylhexanoic acid, >=99%, 2-Ethylhexanoic acid, analytical standard, CAS-149-57-5, 2 ETHYL HEXANOIC ACID, CCRIS 3348, HSDB 5649, NSC 8881, Kyselina 2-ethylkapronova, EINECS 205-743-6, (+/-)-2-ETHYLHEXANOIC ACID, UNII-01MU2J7VVZ, α-Ethylcaproic acid, α-Ethylhexanoic acid, Butylethylacetic acid, Ethylhexanoic acid, Ethylhexoic acid, 2-Butylbutanoic acid, 2-Ethylcaproic acid, 2-Ethylhexanoic acid, 2-Ethylhexoic acid, 3-Heptanecarboxylic acid, Kyselina 2-ethylkapronova, Kyselina heptan-3-karboxylova, 2-Ethyl-1-hexanoic acid, 2-Ethylcapronic acid, NSC 8881, 2-ethylhexyl 2-ethylhexanoate, ETHYLHEXYL ETHYLHEXANOATE, 2-Ethylhexyl-2-ethylhexanoat, 2-Ethylhexanoic acid, 2-ethylhexyl ester, Dragoxate EH, Hexanoic acid, 2-ethyl-, 2-ethylhexyl ester, DRAGOXAT EH, Hexanoic acid,2-ethyl-, Caproic acid,α-ethyl-, 2-Ethylhexanoic acid, Butylethylacetic acid, α-Ethylcaproic acid, 2-Ethylhexoic acid, 3-Heptanecarboxylic acid, 2-Ethylcaproic acid, Ethylhexanoic acid, α-Ethylhexanoic acid, 2-Butylbutanoic acid, 2-Ethyl-1-hexanoic acid, (±)-2-Ethylhexanoic acid, NSC 8881, Octylic acid, 83829-68-9, 202054-39-5 Hexanoic acid, 2-ethyl-, Ethylhexanoic acid, 2-ETHYLCAPROIC ACID, 2-ethylhexanoic, 2-Ethyl-1-hexanoic acid, Ethylhexoic acid, CAPRYLIC ACID(SG), 2-ETHYLCAPRONIC ACID, (RS)-2-Ethylhexansαure, 2-Ethylhexanoic acid, BRN 1750468, Kyselina heptan-3-karboxylova, AI3-01371, Hexanoic acid, 2-ethyl-, (-)-, EINECS 262-971-9, 2-Ethylcapronic acid, 2-Ethyl-Hexonic acid, alpha-Ethylhexanoic acid, .alpha.-Ethylhexanoic acid, EC 205-743-6, SCHEMBL25800, 2-Ethylhexanoic acid, 99%, MLS002415695, CHEMBL1162485, WLN: QVY4 & 2, NSC8881, HMS2267F21, STR05759, 2-ETHYLHEXANOIC ACID [HSDB], Tox21_201406, Tox21_300108, LMFA01020087, AKOS009031416, AT29893, CS-W016381, SB44987, SB44994, Hexanoic acid,2-ethyl-, tridecyl ester, NCGC00091324-01, NCGC00091324-02, NCGC00091324-03, NCGC00253985-01, NCGC00258957-01, SMR001252268, E0120, FT-0612273, FT-0654390, NS00010660, EN300-20410, Q209384, W-109079, F0001-0703, Z104478072, 18FEB650-7573-4EA0-B0CD-9D8BED766547, 2-Ethylhexanoic acid, Pharmaceutical Secondary Standard; Certified Reference Material,



Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a colorless to light yellow liquid with a mild odor.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) will burn though it may take some effort to ignite.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is slightly soluble in water.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is corrosive to metals and tissue.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a branched-chain fatty acid.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a natural product found in Vitis vinifera and Artemisia arborescens with data available.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is found in fruits.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is found in grapes.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) belongs to the family of Branched Fatty Acids.


These are fatty acids containing a branched chain.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a colorless to light yellow liquid with a mild odor.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) will burn though it may take some effort to ignite.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is slightly soluble in water.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is corrosive to metals and tissue.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is an industrial chemical.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a versatile monocarboxylic acid chemical intermediate.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is the organic compound with the formula CH3(CH2)3CH(C2H5)CO2H.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a carboxylic acid that is widely used to prepare lipophilic metal derivatives that are soluble in nonpolar organic solvents.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a colorless viscous oil.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is supplied as a racemic mixture.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a colorless to light yellow liquid with a mild odor.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a colorless to light yellow liquid with a mild odor.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) will burn though it may take some effort to ignite. It is slightly soluble in water.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is corrosive to metals and tissue.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used to make paint dryers and plasticizers.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a colorless to light yellow liquid with a mild odor.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a colorless to light yellow liquid with a mild odor.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) will burn though it may take some effort to ignite.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is slightly soluble in water.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is corrosive to metals and tissue.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used to make paint dryers and plasticizers.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a branched-chain fatty acid.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a colorless to light yellow liquid with a mild odor.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) will burn though it may take some effort to ignite.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is slightly soluble in water.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is corrosive to metals and tissue.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used to make paint dryers and plasticizers.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a colourless liquid



USES and APPLICATIONS of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used in the following products: anti-freeze products, laboratory chemicals and metal working fluids.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used in the following areas: scientific research and development.
Other release to the environment of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is likely to occur from: indoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used in the following products: coating products.
Release to the environment of this substance can occur from industrial use: formulation of mixtures.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used in the following products: coating products, laboratory chemicals, lubricants and greases and metal working fluids.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) can occur from industrial use: manufacturing of the substance.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used to make paint dryers and plasticizers.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used to make paint dryers and plasticizers.
Automotive: Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used in the production of corrosion inhibitors for automotive coolants.
A major use of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is in the preparation of metal salts and soaps used as drying agents in paint and inks, and as thermal stabilizers in polyvinyl chloride (PVC).


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is also used in the manufacture of resins used in automobile windshields and vinyl flooring.
Lubricants uses of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA): Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a major raw material for polyolesters used in synthetic lubricants.


Personal Care: In cosmetics, Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used to produce emollients.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used the production of polyvinylbutyral (PVB) plasticizers and polyvinylchloride (PVC) stabilizers in the form of metal salts.


Other applications of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) include, catalyst for polymer production, raw material for acid chloride and fragrances.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used in the preparation of metal derivatives, which act as a catalyst in polymerization reactions.


For example, tin 2-ethylhexanoate is used in the manufacturing of poly(lactic-co-glycolic acid).
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is also used as a stabilizer for polyvinyl chlorides.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is also involved in solvent extraction and dye granulation.


Further, Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used to prepare plasticizers, lubricants, detergents, flotation aids, corrosion inhibitors and alkyd resins.
In addition to this, Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) serves as a catalyst for polyurethane foaming.


2-Ethylhexanoic acid can be used as a reactant in esterification , decarboxylative alkynylation , and preparation of alkyl coumarins via decarboxylative coupling reactions.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used in the organocatalytic medium for the preparation of various 3,4-dihydropyrimidin-2(1H)-ones/thiones by Biginelli reaction.


Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is used paint and varnish driers (metallic salts).
Ethylhexoates of light metals are used to convert some mineral oils to greases.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA)'s esters are used as plasticizers.


-Coatings uses of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA):
This monomer, Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA), is used in the synthesis of alkyd resins provides improved yellowing resistanct than the standard fatty acids.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is particularly suitable for stoving enamels and two-component coatings.
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is also used as a raw material for metal based paint driers.



PRODUCTION OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is produced industrially from propylene, which is hydroformylated to give butyraldehyde.
Aldol condensation of the aldehyde gives 2-ethylhexenal, which is hydrogenated to 2-ethylhexanal.
Oxidation of this aldehyde gives the carboxylic acid.

*Metal ethylhexanoates
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) forms compounds with metal cations that have stoichiometry as metal acetates.
These ethylhexanoate complexes are used in organic and industrial chemical synthesis.

They function as catalysts in polymerizations as well as for oxidation reactions as "oil drying agents."
They are highly soluble in nonpolar solvents.
These metal complexes are often described as salts.

They are, however, not ionic but charge-neutral coordination complexes.
Their structures are akin to the corresponding acetates.

Examples of metal ethylhexanoates:
Hydroxyl aluminium bis(2-ethylhexanoate), used as a thickener
Tin(II) ethylhexanoate (CAS# 301-10-0), a catalyst for polylactide and poly(lactic-co-glycolic acid).
Cobalt(II) ethylhexanoate (CAS# 136-52-7), a drier for alkyd resins
Nickel(II) ethylhexanoate (CAS# 4454-16-4)



PREPARATION OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
In a dry 1L three-neck bottle, Add isooctyl aldehyde (80g, 0.62mol) And the solvent Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) (240g, 1.66mol), ligand L8 (5.24mg, 0.007mmol), cesium carbonate (18.24mg, 0.056mmol), potassium acetate 160mg, placed in a water bath, mechanical under nitrogen atmosphere

Stir, after the temperature rises to 30 ° C, Air flow was started at a flow rate of 11.9 g/h, and the reaction temperature was maintained at 30-35 ° C by adding cooling water to the water bath.
After 6 hours of reaction, the conversion of isooctyl aldehyde was calculated to be 99.6%.
The selectivity of Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) was 99.5%, and the yield was 99.10%.



ALTERNATIVE PARENTS OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
*Branched fatty acids
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
*Medium-chain fatty acid
*Branched fatty acid
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound



REACTIVITY PROFILE OF HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
Hexanoic acid, 2-ethyl-(2-Ethylhexanoic acid) (2-EHA) is a carboxylic acid.
Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.

Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water.

Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions.
The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt.

Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.
Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in it to corrode or dissolve iron, steel, and aluminum parts and containers.

Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.
The reaction is slower for dry, solid carboxylic acids.
Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.

The reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides generates flammable and/or toxic gases and heat.
Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat.

Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat.
Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents.

These reactions generate heat.
A wide variety of products is possible.
Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.



PHYSICAL and CHEMICAL PROPERTIES of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
Chemical form
Molecular Weight: 144.21100 g/mol
Exact Mass: 144.21
EC Number: 262-971-9
ICSC Number: 0477
NSC Number: 8881
UN Number: 1993
DSSTox ID: DTXSID9025293
Color/Form: Clear liquid
HScode: 29159080
Density: 0.9031 g/cm3 @ 25 °C
Melting Point: -59 °C
Boiling Point: 228 °C
Flash Point: 114ºC
Refractive Index: 1.424-1.426

Water Solubility: Solubility in water, g/100ml: 0.14 (very poor)
Storage Conditions: Keep container closed when not in use.
Store in a cool, dry, well-ventilated area away from incompatible substances.
Vapor Pressure: Vapor Density: 4.98 (vs air)
Flammability Characteristics: Lower flammable limit: 0.8% by volume;
Upper flammable limit: 6.0% by volume
Explosive Limit: vol% in air: 0.8
Odor: Mild odor
Henry's Law Constant: Henry's Law constant = 2.8X10-6 atm-cu m/mol at 25 °C (est)
Experimental Properties: Hydroxyl radical reaction rate constant = 8.18X10-12 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions: No rapid reaction with air.
No rapid reaction with water.
Reactive Group: Acids, Carboxylic

Appearance: Colorless liquid
Density: 903 mg mL−1
Melting point: −59.00 °C; −74.20 °F; 214.15 K
Boiling point: 228.1 °C; 442.5 °F; 501.2 K
log P: 2.579
Vapor pressure: Acidity (pKa): 4.819
Basicity (pKb): 9.178
Refractive index (nD): 1.425
Std enthalpy of formation (ΔfH⦵298): −635.1 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): -4.8013–4.7979 MJ mol−1
Appearance: colorless clear liquid (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.89300 to 0.91300 @ 25.00 °C.

Pounds per Gallon - (est).: 7.431 to 7.597
Refractive Index: 1.42000 to 1.42600 @ 20.00 °C.
Melting Point: -59.00 °C. @ 760.00 mm Hg
Boiling Point: 220.00 to 223.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.030000 mmHg @ 20.00 °C.
Vapor Density: 4.98 ( Air = 1 )
Flash Point: 244.00 °F. TCC ( 117.78 °C. )
logP (o/w): 2.640
Soluble in: alcohol, water, 2000 mg/L @ 20 °C (exp)
Insoluble in: water
Molecular Weight: 144.21 g/mol
XLogP3: 2.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2

Rotatable Bond Count: 5
Exact Mass: 144.115029749 g/mol
Monoisotopic Mass: 144.115029749 g/mol
Topological Polar Surface Area: 37.3Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 99.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Water Solubility: 2.07 g/L

logP: 2.61
logP: 2.8
logS: -1.8
pKa (Strongest Acidic): 5.14
Physiological Charge: -1
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 1
Polar Surface Area: 37.3 Ų
Rotatable Bond Count: 5
Refractivity: 40.25 m³·mol⁻¹
Polarizability: 16.99 ų
Number of Rings: 0
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Autoignition Temperature: 699 °F (USCG, 1999) | 700 °F (371 °C) | 371 °C

Critical Temperature & Pressure:
Critical temperature: 615.2 Kula: C8H16O2
Molar mass: 144.214 g·mol−1
Veber's Rule: Yes
MDDR-like Rule: No
Physical state: clear, liquid
Color: colorless
Odor: No data available
Melting point/freezing point:
Melting point/range: -59 °C
Initial boiling point and boiling range: 228 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 6,7 %(V)
Lower explosion limit: 0,9 %(V)
Flash point: 114 °C - closed cup

Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 3 at 1,4 g/l at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: log Pow: 2,7 at 25 °C
Vapor pressure 13 hPa at 115 °C: < 0,01 hPa at 20 °C
Density: 0,903 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapo density: No data available
Particle characteristics: No data available
Explosive properties: No data available

Oxidizing properties: No data available
Other safety information:
Relative vapor density: 4,98 - (Air = 1.0)
Chemical formula: C8H16O2
Molar mass: 144.214 g·mol−1
Appearance: Colorless liquid
Density: 903 mg mL−1
Melting point: −59.00 °C; −74.20 °F; 214.15 K
Boiling point: 228.1 °C; 442.5 °F; 501.2 K
log P: 2.579
Vapor pressure: Acidity (pKa): 4.819
Basicity (pKb): 9.178
Refractive index (nD) 1.425

Melting point: -59 °C
Boiling point: 228 °C(lit.)
Density: 0.906
vapor density: 4.98 (vs air)
vapor pressure: refractive index: n20/D 1.425(lit.)
Flash point: 230 °F
storage temp.: Store below +30°C.
solubility: 1.4g/l
form: Liquid
pka: pK1:4.895 (25°C)
color: Clear
PH: 3 (1.4g/l, H2O, 20℃)

Odor: Mild odour
PH Range: 3 at 1.4 g/l at 20 °C
Viscosity: 7.73 cps
explosive limit: 1.04%, 135°F
Water Solubility: 2 g/L (20 ºC)
BRN: 1750468
Exposure limits ACGIH: TWA 5 mg/m3
Stability: Stable.
Incompatible with strong oxidizing agents, reducing agents, bases.
InChIKey: OBETXYAYXDNJHR-UHFFFAOYSA-N
LogP: 2.7 at 25℃
CAS DataBase Reference: 149-57-5(CAS DataBase Reference)
EWG's Food Scores: 2

FDA UNII: 01MU2J7VVZ
NIST Chemistry Reference: Hexanoic acid, 2-ethyl-(149-57-5)
EPA Substance Registry System: 2-Ethylhexanoic acid (149-57-5)
Molecular Weight:293.40
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:293.22022309
Monoisotopic Mass:293.22022309
Topological Polar Surface Area:101
Heavy Atom Count:20
Complexity:155
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes



FIRST AID MEASURES of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent and neutralising material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water
system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Viton
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 240 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of HEXANOIC ACID, 2-ETHYL-(2-ETHYLHEXANOIC ACID) (2-EHA):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


HEXANOL
Hexanol is a linear primary alcohol.
Hexanol (IUPAC name hexan-1-ol) is an organic alcohol with a six-carbon chain and a condensed structural formula of CH3(CH2)5OH.
Hexanol is used as a precursor to plasticizers, chemical intermediate for pharmaceuticals, perfume esters and antiseptics.

CAS Number: 111-27-3
EC Number: 203-852-3
Molecular Formula: C6H14O
Molecular Weight (g/mol): 102.177

Two additional straight chain isomers of Hexanol, 2-hexanol and 3-hexanol, exist, both of which differing by the location of the hydroxyl group.
Many isomeric alcohols have the formula C6H13OH.
Hexanol is used in the perfume industry.

Hexanol is used as a precursor to plasticizers, chemical intermediate for pharmaceuticals, perfume esters and antiseptics.
Further, Hexanol serves as a perturbing agent on actomyosin adenosine triphosphatease.
In addition to this, Hexanol is used to modulate the function of actomyosin motor.

Hexanol is an organic alcohol with a six carbon chain and a condensed structural formula of CH3(CH2)5OH.
This colorless liquid is slightly soluble in water, but miscible with ether and ethanol.

Two additional straight chain isomers of Hexanol exist, 2-hexanol and 3-hexanol, both of which differ by the location of the hydroxyl group.
Many isomeric alcohols have the formula C6H13OH.

Hexanol (IUPAC name hexan-1-ol) is an organic alcohol with a six-carbon chain and a condensed structural formula of CH3(CH2)5OH.
This colorless liquid is slightly soluble in water, but miscible with diethyl ether and ethanol.

Hexanol is believed to be a component of the odour of freshly mown grass.
Hexanol is used in the perfume industry.

Hexanol is an organic alcohol with a six carbon chain and a condensed structural formula of CH3(CH2)5OH.
This colorless liquid is slightly soluble in water, but miscible with ether and ethanol.

Hexanol is a linear primary alcohol.
Hexanol is formed as an intermediate during the catalytic transformation of cellulose.

The ability of 1,1,3,3-tetramethylguanidine (TMG) in Hexanol solvent system to capture carbon dioxide has been assessed.
The solubility of light fullerenes in Hexanol as a function of temperature and pressure was studied.

Hexanol is produced from coconut oil and palm oils.
Hexanol is used in the production of antiseptics, fragrances and perfumes.
Hexanol is also used as a solvent in the production of plasticizers.

Two additional straight chain isomers of Hexanol exist, 2-hexanol and 3-hexanol, both of which differ by the location of the hydroxyl group.
Many isomeric alcohols have the formula C6H13OH.
Hexanol is an alcohol extracted from yeast and produced during fermentation of alcoholic beverages.

Applications of Hexanol:
Hexanol is used to make plasticizers for polyvinyl chloride.
Reaction with phthalic anhydride gives bis(2-ethyl hexyl) phthalate (DOP, DEHP).

Reaction with adipic acid gives bis(2-ethyl hexyl) adipate.
Moreover, esterification with acrylic acid gives 2-ethyl hexyl acrylate for use in adhesives and paints.
On the other hand, because Hexanol can dissolve many organic materials well, Hexanol is widely used as a low-volatility solvent.

Hexanol is used as a precursor to plasticizers, chemical intermediate for pharmaceuticals, perfume esters and antiseptics.
Further, Hexanol serves as a perturbing agent on actomyosin adenosine triphosphatease.
In addition to this, Hexanol is used to modulate the function of actomyosin motor.

Uses of Hexanol:
Hexanol is used to produce plasticizers, antiseptics, fragrances, pharmaceuticals, and finishing agents for textile and leather.
Hexanol is used as a flavoring agent and a solvent for fats, waxes, dyes, and paints.

Hexanol is synthetic flavoring ingredient
Hexanol is used in pharmaceuticals (introduction of hexyl group into hyponics, antiseptics, perfume esters, etc), solvent, plasticizer, intermediate for textile and leather finishing agents.

Industry Uses:
Aerating and deaerating agents
Fuel
Intermediate
Lubricating agent
Monomers
Solvent
Solvents (which become part of product formulation or mixture)
Surfactant (surface active agent)
Wetting agent (non-aqueous)

Consumer Uses:
Flavoring and nutrient
Fuel
Lubricating agent
Monomers
Solvent

Industrial Processes with risk of exposure:
Painting (Solvents)

Preparation of Hexanol:
Hexanol is produced industrially by the oligomerization of ethylene using triethylaluminium followed by oxidation of the alkylaluminium products.

An idealized synthesis is shown:
Al(C2H5)3 + 6C2H4 → Al(C6H13)3
Al(C6H13)3 + 1+1⁄2O2 + 3H2O → 3HOC6H13 + Al(OH)3

The process generates a range of oligomers that are separated by distillation.

Alternative methods:
Another method of preparation entails hydroformylation of 1-pentene followed by hydrogenation of the resulting aldehydes.
This method is practiced in industry to produce mixtures of isomeric C6-alcohols, which are precursors to plasticizers.

In principle, 1-hexene could be converted to Hexanol by hydroboration (diborane in tetrahydrofuran followed by treatment with hydrogen peroxide and sodium hydroxide).
This method is instructive and useful in laboratory synthesis but of no practical relevance because of the commercial availability of inexpensive Hexanol from ethylene.

Manufacturing Methods of Hexanol:
Addition of ethylene to triethylaluminum followed by oxidation of the growth product, hydrolysis, and fractional distillation; from condensation of n-butyraldehyde and acetaldehyde, followed by dehydration and hydrogenation.

Laboratory preparation by action of butylmagnesium bromide on ethylene oxide 1,3-hexadienal with iron wire in presence of nickel acetate
Industrial preparation by reducing ethyl caproate with sodium in absolute alcohol.

Reaction of acetaldehyde and crotonaldehyde followed by hydrogenation.

General Manufacturing Information of Hexanol:

Industry Processing Sectors:
Agriculture, Forestry, Fishing and Hunting
All Other Basic Organic Chemical Manufacturing
Mining (except Oil and Gas) and support activities
Oil and Gas Drilling, Extraction, and Support activities
Other (requires additional information)
Paint and Coating Manufacturing
Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing
Petrochemical Manufacturing
Petroleum Lubricating Oil and Grease Manufacturing
Plastics Material and Resin Manufacturing
Plastics Product Manufacturing

Commercial products from the family of 6 to 11 carbon alcohols that make up the plasticizer range are available both as pure single carbon chain materials and as complex isomeric mixtures.
Commercial descriptions of plasticizer range alcohols are in general a pure material is called "-anol" /eg, Hexanol/, and the mixtures are called "-yl alcohol /eg, hexyl alcohol/ or "iso...yl alcohol" /isohexyl alcohol/.

Occurrence in Nature of Hexanol:
Hexanol is believed to be a component of the odour of freshly mown grass.
Alarm pheromones emitted by the Koschevnikov gland of honey bees contain Hexanol.
Hexanol also is partly responsible for the fragrance of strawberries.

Characteristics of Hexanol:
Hexanol, also called octanol, is an 8-carbon higher alcohol species.
Hexanol is hardly soluble in water, but is soluble in almost all organic solvents.
Our Hexanol has very low-level impurities and may be used as a raw material for a wide variety of chemicals.

MeSH Pharmacological Classification of Hexanol:

Nicotinic Antagonists:
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists.
Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.

Anesthetics:
Agents capable of inducing a total or partial loss of sensation, especially tactile sensation and pain.
They may act to induce general ANESTHESIA, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site.

Action Mechanism of Hexanol:
Ethanol and Hexanol were found to have two competing concentration-dependent effects on the Ca(2+)- and phorbol ester- or diacylglycerol-dependent activities of PKCalpha associated with either RhoA or Cdc42, consisting of a potentiation at low alcohol levels and an attenuation of activity at higher levels.
Measurements of the Ca(2+), phorbol ester, and diacylglycerol concentration-response curves for Cdc42-induced activation indicated that the activating effect corresponded to a shift in the midpoints of each of the curves to lower activator concentrations, while the attenuating effect corresponded to a decrease in the level of activity induced by maximal activator levels.
The presence of ethanol enhanced the interaction of PKCalpha with Cdc42 within a concentration range corresponding to the potentiating effect, whereas the level of binding was unaffected by higher ethanol levels that were found to attenuate activity.

Human Metabolite Information of Hexanol:

Cellular Locations:
Extracellular
Membrane

Reactivity Profile of Hexanol:
Hexanol is an alcohol.
Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents.

They react with oxoacids and carboxylic acids to form esters plus water.
Oxidizing agents convert them to aldehydes or ketones.

Alcohols exhibit both weak acid and weak base behavior.
They may initiate the polymerization of isocyanates and epoxides.

Handling and Storage of Hexanol:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling the product must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do Hexanol without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Safe Storage:
Separated from strong oxidants.

Storage Conditions:
Protect containers against physical damage.
Keep containers closed and store in well-ventilated, cool place.

Fire Fighting of Hexanol:
The majority of these products have a very low flash point.
Use of water spray when fighting fire may be inefficient.

SMALL FIRE:
Dry chemical, CO2, water spray or alcohol-resistant foam.
Do not use dry chemical extinguishers to control fires involving nitromethane (UN1261) or nitroethane (UN2842).

LARGE FIRE:
Water spray, fog or alcohol-resistant foam.
Avoid aiming straight or solid streams directly onto the product.
If Hexanol can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out.

Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

For massive fire, use unmanned master stream devices or monitor nozzles.
If this is impossible, withdraw from area and let fire burn.

Use alcohol-resistant foam, dry powder, carbon dioxide.
In case of fire: keep drums, etc., cool by spraying with water.

Fire Fighting Procedures of Hexanol:
Use carbon dioxide, dry chemical or "alcohol" foam extinguisher.
Water is ineffective to fire fighting, but is effective to keep fire-exposed containers cool.

If material on fire or involved in fire:
Do not extinguish fire unless flow can be stopped.
Use water in flooding quantities as fog.

Solid streams of water may be ineffective.
Cool all affected containers with flooding quantities of water.

Apply water from as far a distance as possible.
Use "alcohol" foam, carbon dioxide or dry chemical.
Keep run off water out of sewers and water sources.

Accidental Release Measures of Hexanol:

IMMEDIATE PRECAUTIONARY MEASURE:
Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL:
Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions.
Also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Spillage Disposal of Hexanol:

Personal protection:
Filter respirator for organic gases and vapours adapted to the airborne concentration of Hexanol.
Collect leaking and spilled liquid in covered containers as far as possible.

Absorb remaining liquid in sand or inert absorbent.
Then store and dispose of according to local regulations.

Cleanup Methods of Hexanol:
Absorb on paper.
Evaporate on a glass or iron dish in hood.
Burn the paper.

Disposal Methods of Hexanol:
The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination.
Recycle any unused portion of the material for Hexanol approved use or return it to the manufacturer or supplier.

Ultimate disposal of the chemical must consider:
The material's impact on air quality.
Potential migration in soil or water

Effects on animal, aquatic, and plant life.
Conformance with environmental and public health regulations.

Spray into the furnace.
Incineration will become easier by mixing with a more flammable solvent.

Preventive Measures of Hexanol:

If material not on fire and not involved in fire:
Keep sparks, flames, and other sources of ignition away.
Keep material out of water sources and sewers.

Build dikes to contain flow as necessary.
Attempt to stop leak if without undue personnel hazard.
Use water spray to knock-down vapors.

Personnel protection:
Avoid breathing vapors.
Avoid bodily contact with the material.

Do not handle broken packages unless wearing appropriate personal protective equipment.
Wash away any material which may have contacted the body with copious amounts of water or soap and water.
If contact with the material anticipated, wear appropriate chemical protective clothing.

Identifiers of Hexanol:
CAS Number: 111-27-3
Beilstein Reference 969167
ChEBI: CHEBI:87393
ChEMBL: ChEMBL14085
ChemSpider: 7812
ECHA InfoCard: 100.003.503
EC Number: 203-852-3
MeSH: 1-Hexanol
PubChem CID: 8103
RTECS number: MQ4025000
UNII: 6CP2QER8GS
UN number: 2282
CompTox Dashboard (EPA): DTXSID8021931
InChI: InChI=1S/C6H14O/c1-2-3-4-5-6-7/h7H,2-6H2,1H3
Key: ZSIAUFGUXNUGDI-UHFFFAOYSA-N
SMILES: CCCCCCO

CAS number: 111-27-3
EC index number: 603-059-00-6
EC number: 203-852-3
Hill Formula: C₆H₁₄O
Molar Mass: 102.18 g/mol
HS Code: 2905 19 00

Synonym(s): Hexyl alcohol
Linear Formula: CH3(CH2)5OH
CAS Number: 111-27-3
Molecular Weight: 102.17
Beilstein: 969167
EC Number: 203-852-3
MDL number: MFCD00002982
PubChem Substance ID: 57650899
NACRES: NA.21

CAS: 111-27-3
Molecular Formula: C6H14O
Molecular Weight (g/mol): 102.177
MDL Number: MFCD00002982
InChI Key: ZSIAUFGUXNUGDI-UHFFFAOYSA-N
PubChem CID: 8103
ChEBI: CHEBI:87393
IUPAC Name: hexan-1-ol
SMILES: CCCCCCO

Properties of Hexanol:
Chemical formula: C6H14O
Molar mass: 102.177 g·mol−1
Appearance colorless: liquid
Density: 0.82 g cm−3 (at 20 °C)[2]
Melting point: −45 °C (−49 °F; 228 K)
Boiling point: 157 °C (315 °F; 430 K)
Solubility in water: 5.9 g/L (at 20 °C)
log P: 1.858
Vapor pressure: 100 Pa (at 25.6 °C)
Refractive index (nD): 1.4178 (at 20 °C)

Density: 0.82 g/cm3 (20 °C)
Explosion limit: 1.2 - 7.7 %(V)
Flash point: 60 °C
Ignition temperature: 285 °C
Vapor pressure: 3.64 hPa (38 °C)
Viscosity kinematic: 3.64 mm2/s (40 °C)
Solubility: 1.3 g/l

Grade: anhydrous
Quality Level: 100
Vapor density: 4.5 (vs air)
Vapor pressure: 1 mmHg ( 25.6 °C)
Assay: ≥99%
Form: liquid
Autoignition temp.: 559 °F
Expl. lim.: 0.34-6.3 %
Impurities: <0.005% water
evapn. residue: <0.0005%
Refractive index: n20/D 1.418 (lit.)
bp: 156-157 °C (lit.)
mp: −52 °C (lit.)
Density: 0.814 g/mL at 25 °C (lit.)
SMILES string: CCCCCCO
InChI: 1S/C6H14O/c1-2-3-4-5-6-7/h7H,2-6H2,1H3
InChI key: ZSIAUFGUXNUGDI-UHFFFAOYSA-N

Molecular Weight: 102.17
XLogP3: 2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 4
Exact Mass: 102.104465066
Monoisotopic Mass: 102.104465066
Topological Polar Surface Area: 20.2 Ų
Heavy Atom Count: 7
Complexity: 27.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Hexanol:
Assay (GC, area%): ≥ 98 %
Density (d 20 °C/ 4 °C): 0.818 - 0.819
Identity (IR): passes test

Melting Point: -52°C
Density: 0.814
Boiling Point: 157°C
Flash Point: 60°C (140°F)
Assay Percent Range: 99%
Linear Formula: CH3(CH2)5OH
UN Number: UN2282
Beilstein: 969167
Merck Index: 14,4697
Refractive: Index 1.418
Quantity: 2500 mL
Solubility Information: Miscible with ethanol, acetone, chloroform, ether, benzene. Slightly miscible with carbon tetrachloride and water.
Formula Weight: 102.18
Percent Purity: 99%
Chemical Name or Material: 1-Hexanol

Thermochemistry of Hexanol:
Heat capacity (C): 243.2 J K−1 mol−1
Std molar entropy (S⦵298): 287.4 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): −377.5 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −3.98437 MJ mol−1

Names of Hexanol:

Preferred IUPAC name:
Hexan-1-ol

Other names:
amyl carbinol

Synonyms of Hexanol:
1-Hexanol
Hexan-1-ol
Hexyl alcohol
111-27-3
HEXANOL
n-Hexanol
n-Hexyl alcohol
Amylcarbinol
1-Hydroxyhexane
1-Hexyl alcohol
Caproyl alcohol
Pentylcarbinol
Caproic alcohol
n-Hexan-1-ol
C6 alcohol
Alcohol(C6)
Hexanol (VAN)
EPAL 6
Hexyl alcohol (natural)
Alcohol C-6
FEMA No. 2567
NSC 9254
MFCD00002982
Hexanol-(1)
6CP2QER8GS
25917-35-5
CHEBI:87393
NSC-9254
Caswell No. 482E
Hydroxyhexane
Hexanols
FEMA Number 2567
CAS-111-27-3
HE2
HSDB 565
EINECS 203-852-3
UNII-6CP2QER8GS
EPA Pesticide Chemical Code 079047
BRN 0969167
Caproalcohol
Hexalcohol
HEXYL ALCOHOL, ACTIVE
n-hexylalcohol
AI3-08157
N-hexenol
Nat.Hexanol
Exxal 6
EINECS 247-346-0
HEXANOL-CMPD
Exxal 6 (Salt/Mix)
BDBM9
1-Hexanol, 98%
Hexyl alcohol, FCC, FG
1-HEXANOL [HSDB]
1-HEXANOL [MI]
EC 203-852-3
n-C6H13OH
SCHEMBL1877
HEXYL ALCOHOL [FCC]
NATURAL HEXYL ALCOHOL
C6H13OH
HEXYL ALCOHOL [FHFI]
HEXYL ALCOHOL [INCI]
WLN: Q6
4-01-00-01694 (Beilstein Handbook Reference)
MLS001055374
UN 2282 (Salt/Mix)
BIDD:ER0298
CHEMBL14085
1-Hexanol, analytical standard
DTXSID8021931
1-Hexanol, anhydrous, >=99%
NSC9254
1-Hexanol, reagent grade, 98%
DTXSID001022586
HMS3039L08
BCP29486
ZINC1699882
Tox21_201335
Tox21_302953
LMFA05000117
STL282713
UN2282
AKOS009031422
HY-W032022
Alcohol C-6, Natural, Natural Hexanol
1-Hexanol, purum, >=98.0% (GC)
1-Hexyl alcohol pound>>1-Hexylalcohol
NCGC00090949-01
NCGC00090949-02
NCGC00256385-01
NCGC00258887-01
Hexanols [UN2282] [Flammable liquid]
LS-13216
SMR000677945
1-Hexanol, SAJ special grade, >=99.0%
1-Hexanol, Vetec(TM) reagent grade, 98%
CS-0076046
FT-0607887
H0130
Hexyl alcohol, natural, >=98%, FCC, FG
EN300-19338
Q76933
1-Hexanol, ReagentPlus(R), >=99.5% (GC)
J-002549
F0001-0237
Z104473568
111-27-3 [RN]
1-Hexanol [ACD/Index Name] [ACD/IUPAC Name]
1-Hexanol [German] [ACD/Index Name] [ACD/IUPAC Name]
1-Hexanol [French] [ACD/Index Name] [ACD/IUPAC Name]
1-hexyl alcohol
1-Hydroxyhexane
203-852-3 [EINECS]
4-01-00-01694 [Beilstein]
Caproic alcohol
Caproyl alcohol
hexan-1-ol
hexanol [Wiki]
Hexyl alcohol
MFCD00002982 [MDL number]
n-Hexan-1-ol
n-hexanol
n-Hexyl alcohol
1-Hexan-d13-ol
1-hexanol [Portuguese] [ACD/Index Name] [ACD/IUPAC Name]
1-hexanol, purified
52598-04-6 [RN]
BNG
B-Nonylglucoside
C8E
decane, 1,3,5,7-Tetraazatricyclo(3.3.1.13,7)
Epal 6
Exxal 6
Hexalin
Hexane [ACD/Index Name] [ACD/IUPAC Name]
Hexyl alcohol203-852-3MFCD00002982
Hexylalcohol
n-C6H13OH [Formula]
HEXANOL (CAPROIC ALCOHOL)
Hexanol (Caproic Alcohol) is an organic alcohol with a six-carbon chain and a condensed structural formula of CH3(CH2)5OH.
Hexanol (Caproic Alcohol) colorless liquid is slightly soluble in water, but miscible with diethyl ether and ethanol.
Two additional straight chain isomers of 1-hexanol, 2-hexanol and 3-hexanol, exist, both of which differing by the location of the hydroxyl group.

CAS: 111-27-3
MF: C6H14O
MW: 102.17
EINECS: 203-852-3

Many isomeric alcohols have the formula C6H13OH.
Hexanol (Caproic Alcohol) is used in the perfume industry.
Colorless liquid.
The boiling point is 157 ° C; the relative density is 0.819.
Miscible in ethanol, propylene glycol and oil.
There are light blue shoots breath, wine, fruit and fat flavor.
Naturally occurs in some fruits such as apples, strawberries, bitter oranges, also found in camphor oil, tea leaves, tobacco leaves, eucalyptus and coffee.
Hexanol (Caproic Alcohol) appears as colorless transparent liquid with fruit-like aroma at low concentration.
Sweet; rapidly oxidized in the air; can have polymerization reaction upon contact with concentrated inorganic acid.
Similar to normal fatty aldehydes, Hexanol (Caproic Alcohol) can be oxidized to caproic acid and reduced to hexanol.

Hexanol (Caproic Alcohol) has a fruity odor and aromatic flavor.
May be synthesized by reduction of n-caproic acid; the n-hexyl alcohol represents one of the 14 possible isomers of this alcohol.
A primary alcohol that is Hexanol (Caproic Alcohol) substituted by a hydroxy group at position 1.
Hexanol (Caproic Alcohol) is an organic alcohol, which has application in the synthesis of antiseptics, fragrances, perfumes, etc.
Hexanol (Caproic Alcohol) is also used as a component of plasticizers.

Hexanol (Caproic Alcohol) Chemical Properties
Melting point: -52 °C (lit.)
Boiling point: 156-157 °C (lit.)
Density: 0.814 g/mL at 25 °C (lit.)
Vapor density: 4.5 (vs air)
Vapor pressure: 1 mm Hg ( 25.6 °C)
Refractive index: n20/D 1.418(lit.)
FEMA: 2567 | HEXYL ALCOHOL
Fp: 140 °F
Storage temp.: no restrictions.
Solubility ethanol: soluble(lit.)
Pka: 15.38±0.10(Predicted)
Form: Liquid
Color: Clear colorless
Relative polarity: 0.559
Odor: Sweet; mild.
Odor Threshold: 0.006ppm
Odor Type: herbal
Explosive limit: 1.2-7.7%(V)
Water Solubility: 6 g/L (25 ºC)
JECFA Number: 91
Merck: 14,4697
BRN: 969167
Stability: Stable. Substances to be avoided include strong acids, strong oxidizing agents. Combustible.
LogP: 1.8
CAS DataBase Reference: 111-27-3(CAS DataBase Reference)
NIST Chemistry Reference: Hexanol (Caproic Alcohol) (111-27-3)
EPA Substance Registry System: Hexanol (Caproic Alcohol) (111-27-3)

Hexanol (Caproic Alcohol) has an herbaceous, woody, fragrant, mild, sweet, green fruity odor and aromatic flavor.
Hexanol (Caproic Alcohol) is a liquid at room temperature.
The absolute perceived concentration has been reported as 0.01 ppm, and the recognition level is 0.09 ppm .

Content Analysis
Add 700 ml of newly distilled pyridine into a 1000 ml brown bottle with a glass stopper; add phthalic anhydride 11 5g with strong shaking to complete dissolution.
Take the solution 25.0ml, adding into a bottle with heat pressure resistance.
The bottle are tightly wrapped and fixed.
Weigh the sample about 1 g with the weighing pipette; add it into the pressure bottle; stamped.
The sample was fixed in a canvas bag, heated in a water bath at 98~100 ℃ for 3h, and let the water level in the water bath higher than the bottle level.

After removal, cool Hexanol (Caproic Alcohol) to room temperature; carefully open the stopper, and do not make a content loss.
Add 0.5mol/L sodium hydroxide solution 50.0ml (Note: This 50.0ml 0.5mol/L sodium hydroxide solution is not included in the final calculation).
Add 1% phenolphthalein 5 drops of pyridine solution, and then 0.5 mol/L sodium hydroxide solution to the pink end point and maintain 15 s unchanged.
At the same time carry out a blank test. Per milliliter of sodium hydroxide solution 0.5mol/L is equivalent to alcohol (C6H14O) 51.09 mg.
Or measured by non-polar column in GT-10-4 gas chromatography.

Uses
Hexanol (Caproic Alcohol) often acts as part of the head incense used in fragrance base and formulated essential oil (such as geraniol oil).
A trace of Hexanol (Caproic Alcohol) is used for violet, sweet-scented osmanthus, magnolia, ylang-type flavor to modify or increase the tender atmosphere, as well as used for edible coconut formula, berries and various types of fruit flavor.
Hexanol (Caproic Alcohol) is used as solvents and analytical reagents, also used in the pharmaceutical industry for preservatives and sleeping pills.
The goods are listed in China's GB 2760-96.

Hexanol (Caproic Alcohol) is mainly used to prepare coconut and berry flavor and used for the production of surfactants, plasticizers, fatty alcohols and so on.
Hexanol (Caproic Alcohol) is also used for chromatography reagents and organic synthesis.
Gas chromatography analysis standards.
Lithium chloride was isolated from potassium chloride and sodium chloride.
In the synthesis of spices and the preparation of caproic acid; also used as gas chromatography reagents for Wittig and Aldol reactions.
Hexanol (Caproic Alcohol) was examined as a perturbing agent on actomyosin ATPase and and was found to modulate the function of actomyosin motor via intermediate-specific structural perturbation.

Hexanol (Caproic Alcohol) is used as a precursor to plasticizers, chemical intermediate for pharmaceuticals, perfume esters and antiseptics.
Further, Hexanol (Caproic Alcohol) serves as a perturbing agent on actomyosin adenosine triphosphatease.
In addition to this, Hexanol (Caproic Alcohol) is used to modulate the function of actomyosin motor.
Hexanol (Caproic Alcohol) has been used as an odorant to study olfactory responses and to thin the dielectric layer of poly(4-vinylphenol) (PVP).

Production methods
(1) Hexanol (Caproic Alcohol) is generally derived from acetic acid reduction in industry.
Bromine butane and magnesium shards reaction obtains butyl magnesium bromide, and the butyl magnesium bromide reacted with ethylene oxide to get ethanol under laboratorial study.
(2) Via n-hexylic acid reduction.

Production Methods
Hexanol (Caproic Alcohol) is commercially prepared from the addition of ethylene to triethylaluminum followed by oxidation.
Hexanol (Caproic Alcohol) is also produced from natural products derived from coconut or palm oils.

Preparation
Hexanol (Caproic Alcohol) is produced industrially by the oligomerization of ethylene using triethylaluminium followed by oxidation of the alkylaluminium products.
An idealized synthesis is shown:

Al(C2H5)3 + 6C2H4 → Al(C6H13)3
Al(C6H13)3 + 1+1⁄2O2 + 3H2O → 3HOC6H13 + Al(OH)3
The process generates a range of oligomers that are separated by distillation.

Health Hazard
Recommended Personal Protective Equipment: Chemical gloves; chemical goggles; Symptoms Following Exposure: Liquid causes eye burns and skin irritation.
Breathing vapors is not expected to cause systemic illness; General Treatment for Exposure: In case of contact, immediately flush skin and eyes with plenty of water.
Wash eyes at least 15 min. and get medical care; Toxicity by Inhalation (Threshold Limit Value): Data not available; Short-Term Inhalation Limits: Data not available; Toxicity by Ingestion: Grade 2, LD50 = 0.5 to 5 g/kg (rat); Late Toxicity: Data not available; Vapor (Gas) Irritant Characteristics: Data not available; Liquid or Solid Irritant Characteristics: Causes smarting of the skin and first-degree burns on short exposure; may cause second-degree burns on long exposure; Odor Threshold: Data not available.

Health Hazard
Vapors of Hexanol (Caproic Alcohol) are irritant to the eyesand respiratory tract.
Application of the liquid produced severe irritation in rabbits’eyes.
Hexanol (Caproic Alcohol) exhibits narcotic effects at high concentrations.
Hexanol (Caproic Alcohol) was not a skin tumor promoter when applied three times a week for 60 weeks to mice skin that had been initiated with dimethylbenz[a] anthracene.

Chemical Reactivity
Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Synonyms
1-Hexanol
Hexan-1-ol
Hexyl alcohol
111-27-3
HEXANOL
n-Hexanol
n-Hexyl alcohol
Amylcarbinol
1-Hydroxyhexane
1-Hexyl alcohol
Caproyl alcohol
Pentylcarbinol
Caproic alcohol
n-Hexan-1-ol
C6 alcohol
Alcohol(C6)
Hexanol (VAN)
EPAL 6
Hexyl alcohol (natural)
Alcohol C-6
Caswell No. 482E
FEMA No. 2567
FEMA Number 2567
NSC 9254
MFCD00002982
Hexanol-(1)
HSDB 565
n-Hexyl--d5 Alcohol
1-Hexanol-13C6
EINECS 203-852-3
UNII-6CP2QER8GS
6CP2QER8GS
EPA Pesticide Chemical Code 079047
BRN 0969167
AI3-08157
25917-35-5
DTXSID8021931
CHEBI:87393
NSC-9254
EINECS 247-346-0
EC 203-852-3
4-01-00-01694 (Beilstein Handbook Reference)
DTXCID201931
Hydroxyhexane
Hexanols
N-HEXYL-1,1-D2 ALCOHOL
286013-16-9
64118-18-9
CAS-111-27-3
pentilcarbinol
Amilcarbinol
Caproalcohol
Hexalcohol
HEXYL ALCOHOL, ACTIVE
n-hexylalcohol
Alcohol hexilo
1-hidroxihexano
Alcool hexylique
N-hexenol
alcohol n-hexilo
N-HEXYL-2,2,3,3,4,4,5,5,6,6,6-D11 ALCOHOL
1-hexilo alcohol
Exxal 6
2159-18-4
Hexan- 1- ol
HEXANOL-CMPD
Hexyl alcohol (8CI)
hexan - 1 - ol
Exxal 6 (Salt/Mix)
HXN (CHRIS Code)
BDBM9
1-Hexanol, 98%
Hexyl alcohol, FCC, FG
n-Hexan-1-ol, n-hexanol
1-HEXANOL [HSDB]
1-HEXANOL [MI]
n-C6H13OH
SCHEMBL1877
HEXYL ALCOHOL [FCC]
C6H13OH
HEXYL ALCOHOL [FHFI]
HEXYL ALCOHOL [INCI]
WLN: Q6
MLS001055374
UN 2282 (Salt/Mix)
BIDD:ER0298
CHEMBL14085
1-Hexanol, analytical standard
1-Hexanol, anhydrous, >=99%
NSC9254
1-Hexanol (Langkettige Alkohole)
1-Hexanol, reagent grade, 98%
Hexanol, n-; (n-Hexyl alcohol)
DTXSID001022586
HMS3039L08
BCP29486
Tox21_201335
Tox21_302953
LMFA05000117
STL282713
UN2282
AKOS009031422
HY-W032022
LS-2366
1-Hexanol, purum, >=98.0% (GC)
1-Hexyl alcohol pound>>1-Hexylalcohol
NCGC00090949-01
NCGC00090949-02
NCGC00256385-01
NCGC00258887-01
Hexanols [UN2282] [Flammable liquid]
PD158361
SMR000677945
1-Hexanol, SAJ special grade, >=99.0%
1-Hexanol, Vetec(TM) reagent grade, 98%
CS-0076046
FT-0607887
H0130
Hexyl alcohol, natural, >=98%, FCC, FG
EN300-19338
Q76933
1-Hexanol, ReagentPlus(R), >=99.5% (GC)
J-002549
F0001-0237
Z104473568
InChI=1/C6H14O/c1-2-3-4-5-6-7/h7H,2-6H2,1H
HEXASOL
Hexasol is a clear, practically colorless, liquid.
Hexasol is characterized as a clear, colorless, and odorless liquid that finds extensive use in numerous industries, such as cosmetics and personal care products.


CAS Number: 107-41-5
EC Number: 203-489-0
MDL number: MFCD00004547
Chem/IUPAC Name: 2-Methylpentane-2,4-diol
Molecular Formula: C6H14O2 or (CH3)2COHCH2CHOHCH3



2-Methyl-2,4-Pentanediol, 2-Methylpentane-2,4-Diol, Diolane, Hexylene Glycol (2-Methyl-2,4-Pentanediol, Isol, Pinakon, MPD, Hexane-1,2-Diol, (4S)-2-Methylpentane-2,4-Diol, (4R)-2-Methylpentane-2,4-Diol, Hexasol, 2,4-dihydroxy-2-methylpentane, 2-methyl-2,4-pentanediol, 4-methyl-2,4-pentanediol, 2-methylpentane-2,4-diol, 2,4-Dihydroxy-2-methylpentane, 2-Methyl-2,4-pentanediol, 4-Methyl-2,4-pentanediol, 2-Methylpentane-2,4-diol, 2,4-Pentanediol, 2-methyl-, α,α,α'-Trimethyltrimethylene glycol, Diolane, Isol, 1,1,3-Trimethyltrimethylenediol, 2-Methyl-2,4-pentandiol, 2-Methyl-2,4-pentanediol, 2,4-Dihydroxy-2-methylpentane, 4-Methyl-2,4-pentanediol, 2-Methyl pentane-2,4-diol, 2-Methylpentan-2,4-diol, Pinakon, 4-Methyl-2,4-pentanediole, (.+/-.)-2-Methyl-2,4-pentanediol, NSC 8098, Isophthalic acid, 2-Methyl-2,4-pentanediol1,1,3-Trimethyltrimethylenediol2,4-Dihydroxy-2-methylpentane2-Methyl pentane-2,4-diol4-Methyl-2,4-pentanediolTrimethyltrimethylene glycolDiolaneIsolPinakonHexG, (2,4-dihydroxy-2-methylpentane, 2,4-pentanediol, 2-methyl-, 2-methylpentane-2,4-diol, 4-methyl-2,4-pentanediol, alpha,alpha,alpha’-trimethyltrimethylene glycol, diolane, hexylene glycol, isol, pinakon, 2,4-Pentanediol,2-methyl-, 2-Methyl-2,4-pentanediol, 2,4-Dihydroxy-2-methylpentane, Diolane, Hexylene glycol, Isol, α,α,α′-Trimethyltrimethylene glycol, 1,1,3-Trimethyltrimethylenediol, MPD, (±)-2-Methyl-2,4-pentanediol, NSC 8098, Hexasol, Isohexanediol, 99113-75-4, 2-furanmethanol, 2-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, Hexylene glycol, 2-METHYL-2,4-PENTANEDIOL, 107-41-5, 2-Methylpentane-2,4-diol, Diolane, Pinakon, 2,4-Pentanediol, 2-methyl-, 2,4-Dihydroxy-2-methylpentane, Isol, 4-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, Caswell No. 574, 2-Methyl pentane-2,4-diol, 2-Methyl-2,4-pentandiol, hexyleneglycol, HSDB 1126, UNII-KEH0A3F75J, (+-)-2-Methyl-2,4-pentanediol, NSC 8098, NSC-8098, EINECS 203-489-0, KEH0A3F75J, alpha,alpha,alpha'-Trimethyltrimethylene glycol, EPA Pesticide Chemical Code 068601, BRN 1098298, 1,3-dimethyl-3-hydroxybutanol, CCRIS 9439, DTXSID5021885, CHEBI:62995, AI3-00919, Hexylene glycol [NF], 1,3,3-trimethyl-1,3-propanediol, TRACID RUBINE 5BL, DTXCID101885, EC 203-489-0, 1,1,3-trimethyl-1,3-propanediol, 4-01-00-02565 (Beilstein Handbook Reference), Hexylene glycol (NF), 7-MethylAtracuriumDimesylate(MixtureofDiastereomers), MPD, CAS-107-41-5, 2-Methylpentan-2,4-diol, 2-Methyl-pentane-2,4-diol, 64229-01-2, MFCD00004547, Hexylene glycol, 99%, R-(-)-2-METHYL-2,4-PENTANEDIOL, 2methyl-2,4-pentanediol, Hexylene glycol, >=99%, Hexylene glycol, 99.5%, SCHEMBL19379, 1,3-Trimethyltrimethylenediol, CHEMBL2104293, NSC8098, (?)-2-Methyl-2,4-pentanediol, SVTBMSDMJJWYQN-UHFFFAOYSA-N, HMS3264E19, HY-B0903, Hexylene glycol, analytical standard, Tox21_201975, Tox21_302818, s3588, AKOS015901459, CCG-213719, WLN: QY1 & 1XQ1 & 1, NCGC00249143-01, NCGC00256494-01, NCGC00259524-01, AC-13749, AS-58339, Hexylene glycol, BioXtra, >=99% (GC), (+/-)-2-Methyl-2,4-pentanediol, MPD, FT-0605050, FT-0605756, FT-0613069, Hexylene glycol, puriss., >=99.0% (GC), M0384, (S)-(-)-2-METHYL-2,4-PENTANEDIOL, .alpha.,.alpha.'-Trimethyltrimethylene glycol, Hexylene glycol, BioUltra, >=99.0% (GC), D04439, EN300-170052, AB01563179_01, J-640306, J-660006, Q2792203, W-108748, Z1255485267, Hexylene glycol, United States Pharmacopeia (USP) Reference Standard, Diolane, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, MPD, MVD, FP17780, NSC 66498, Einecs 227-150-, 3-Methylpentanediol-2,4, 2-METHYLPENTANE-2,4-DIOL, 3-METHYL-2,4-PENTANEDIOL, 3-methyl-pentane-2,4-diol, 2,4-Pentanediol, 3-methyl-, HGL, Diolane, Isol, Pinakon, 1,1,3-Trimethyl-Triethylenediol, Diacetone Glycol, Methylamilene Glycol, 2,4-Dihydroxy-2- Methyl-Penthane, 2-Methyl-Penthane-2,4-Diol., (+-)-2-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, 2,4-Pentanediol, 2-methyl-, 2-Methyl pentane-2,4-diol, 2-Methyl-2,4-pentanediol, 4-Methyl-2,4-pentanediol, Diolane, Hexylene glycol, Isol, Pinakon, alpha,alpha,alpha'-Trimethyltrimethylene glycol, HGL, 1, 1, 3-Trimethyl-Triethylenediol, Diacetone Glycol, Methylamilene Glycol, 2, 4-Dihydroxy-2-Methyl-Penthane, 2-Methyl-Penthane-2, 4-Diol, 2-Hexyl-1,3-dioxolan-2-one, Hexylene Glycol, HG, 2,4-Dihydroxy-2-methylpentane, 2-Methyl-2,4-, pentanediol, 2-Methylpentane-2,4-diol, Pentane-2,4-, diol, 2-methyl,





Hexasol is fully miscible in water and has the chemical formula C6H14O2.
Hexasol is a compound that appears in a large number of products that are used commercially and industrially
Hexasol has a low evaporation rate and it is completely miscible with water.


Hexasol is a clear, practically colorless, liquid.
Hexasol is characterized as a clear, colorless, and odorless liquid that finds extensive use in numerous industries, such as cosmetics and personal care products.


Hexasol′s a category of glycol often utilized as a solvent, humectant, and an agent to control viscosity.
Hexasol, alternative to PG or DEG or MEG in paint formulation in lowering total VOC content.
Hexasol is a small molecular weight surfactant, widely used as an industrial coating solvent, does not cause adverse health or environmental effects.


Hexasol is an oily colorless liquid with a mild sweet odor.
Hexasol floats and mixes slowly with water.
Hexasol is an oily colorless liquid with a mild sweet odor.


It is thanks to this that Hexasol has an influence on the consistency of the product.
Hexasol is safe for pregnant women and does not cause allergies.
Hexasol is a biodegradable, colorless liquid that is miscible with water and mainly used as a solvent or coupling agent


Hexasol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.
Hexasol is fully miscible in water and has the chemical formula C6H14O2.
Hexasol is a compound that appears in a large number of products that are used commercially and industrially.


Hexasol floats and mixes slowly with water.
2-methylpentane-2,4-diol is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).
Hexasol is a clear, colorless liquid.


Similar to other glycols, Hexasol's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable.
Hexasol is a synthetic substance added to many cosmetics.
Hexasol is an aroma compound and has a preservative effect.


At the same time, Hexasol is also a cleaning agent and detergent.
The most important, however, is the emulsifying property of this glycol.
Hexasol, from Solvay, is an oxygenated solvent derived from acetone which has two alcohol functions.


This speciality ingredient, Hexasol, demonstrates a low evaporation rate and is completely miscible with water.
Hexasol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.
Hexasol is famous for its excellent solvency among a wide variety of materials and is popular in skin care formulas due to its ability to improve the texture.


Hexasol has viscosity-reducing properties that allow it to thin out heavy, thick formulations and produce smooth spreadability.
Hexasol has the chemical formula C6H14O2 and is fully miscible in water.
Hexasol is an ingredient used in skincare and cosmetic products to help improve the texture and sensory feel of the formulation.


Hexasol functions as a surfactant, emulsifier, and a viscosity-reducing agent.
Hexasol, also known as 2-Methyl-2,4-pentanediol, is an organic compound that can be classified as a glycol.
Glycols are a class of alcohols that contain two hydroxyl groups, which can also be called a diols.


Hexasol is a clear, hygroscopic liquid with a mild, sweet odor.
The principal end uses of Hexasol include industrial solvent, chemical intermediate, cosmetics, excipient in pharmaceuticals, paints and coatings.
Hexasol is available in technical grade and NF grade.


Hexasol is an oxygenated solvent derived from acetone which has two alcohol functions.
Hexasol has a low evaporation rate and it is completely miscible with water.
Hexasol is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.


Hexasol is 2-methyl-2,4-pentanediol.
Hexasol is used as coupling agent.
Hexasol offers low flammability and low evaporation rate.


Hexasol possesses low surface tension.
Hexasol exhibits very good solvency.
Hexasol is a clear, colorless liquid that is used in many personal care and cosmetic formulations.


Studies indicate Hexasol also exhibits antimicrobial properties.
Hexasol also goes by its chemical compound name: 2-Methyl-2,4-pentanediol.
As a raw material, Hexasol is a clear liquid.


Hexasol largely acts as a solvent, humectant, and viscosity agent.
Decades of research have established Hexasol as a safe and effective ingredient.
Hexasol dissolves other ingredients in a product and enhances its stability and texture.


In nature, Hexasol is found in the tobacco plant (Nicotiana tabacum).
For industrial purposes Hexasol is formed from the achiral reagents, diacetone alcohol, and hydrogen, producing equal amounts of enantiomeric products.
Commercial Hexasol contains > 99% 2-methyl-2,4-pentanediol and is described as a racemic mixture containing equal amounts of two enantiomers.


Hexasol is a small molecular weight surfactant.
Hexasol also has a low viscosity that makes it easier to incorporate.
The chemical formula of Hexasol is C6H14O2.


Hexasol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.
Hexasol is considered safe for use in cosmetics when used in accordance with regulations and guidelines.
Hexasol is a chemical compound used in various industries, including cosmetics and personal care products.


Hexasol serves as a solvent and a humectant in these products, helping to retain moisture and improve their texture.
Hexasol is most often synthetically produced.
Hexasol is manufactured by the condensation of 2 molecules of acetone to produce diacetone alcohol, which is further hydrogenated to produce Hexasol.


This is then purified.
Hexasol is a clear, colorless liquid chemical compound with the molecular formula C6H14O2.
Hexasol belongs to a class of chemicals known as glycols, which are often used as solvents, humectants, and chemical intermediates in various industrial applications.


Hexasol is commonly used in the cosmetic and personal care industry, where it functions as a solvent and a humectant in products like moisturisers, lotions, and hair care products.
Hexasol helps to maintain moisture and improve the texture of these products.


Additionally, Hexasol has applications in perfumes, as a fragrance fixative, and in the production of various chemicals and coatings.
Hexasol is considered safe for use in cosmetics when used in compliance with regulations and guidelines.
Hexasol is a diol (with two hydroxy groups at 2 and 4 positions), a colorless liquid with a mildly sweet odor and oily consistency.



USES and APPLICATIONS of HEXASOL:
Hexasol is a cosmetic material for FDA regulated product use.
In cosmetics and personal care products, these ingredients are used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.


Additionally, Hexasol helps to decrease the skin′s surface tension, thereby facilitating the penetration of other ingredients into the skin.
Hexasol is mainly used as a solvent or coupling agent.
Hexasol is a potential substitute for glycol ethers.


Hexasol is a moisturising, and setting, agent in the manufacture of textiles and can also be found in the cosmetics industry where it is a component of fragrances and bath, hair, and soap preparations.
Hexasol also has a role as a wetting agent in pesticide formulations and is a solvent in the preparation of dyes.


Hexasol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexasol can also be used as a building block in chemical synthesis.
Hexasol is mainly used as a solvent or coupling agent.


Moreover, Hexasol acts as a reagent in the synthesis of diverse chemicals.
With regard to scientific research applications, Hexasol serves as a solvent to extract an array of compounds from plant and animal tissues.
Hexasol′s also employed as a reagent in the creation of various chemicals, including agrochemicals and fragrances.


Hexasol as a surfactant helps to cleanse and moisturize the skin as well as thinning out the formulation to improve absorption, texture and allow other ingredients to work better.
Hexasol is also used as a chemical intermediate in chemical syntheses, downhole lubricant for natural gas and oil fields, hydraulic fluid, antifreeze, fuel additive, the solvent in dyes and inks, leather and textile processing, industrial and household cleaners, and in cosmetics.


The largest end use for Hexasol is in industrial coatings, as a solvent plasticizer in varnishes, lacquers, paints, and paint strippers, accounting for about 45% of the total production.
Hexasol is often used in preservative blends that contain phenoxyethanol because it boosts the efficacy of this preservative, allowing lower amounts to be used, which reduces the risk skin will have a sensitised response.


Hexasol is mainly used as a solvent or coupling agent.
Hexasol is a potential substitute for glycol ethers.
Hexasol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.


Hexasol is a compound that appears in a large number of products that are used commercially and industrially.
Hexasol is used widely across skincare, hair care, and makeup to enhance spreadability, thin out overly thick formulas, and ensure actives are fully dissolved and dispersed.


Hexasol also has some antimicrobial effect and can enhance the efficacy of certain preservatives.
Hexasol is used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products at concentrations ranging from 0.1% – 25%.


Hexasol can also be used as a building block in chemical synthesis.
In addition to skin care, Hexasol is used in other beauty products including hair care and makeup.
Hexasol has been backed as a safe ingredient for decades with reported concentrations up to 25% in personal care products (though most skin care formulas use much lower amounts than that, especially in preservative blends).


Hexasol is a potential substitute for glycol ethers.
Hexasol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexasol can also be used as a building block in chemical synthesis.


Hexasol is also used as a chemical intermediate, which accounts for approximately 20% of its consumption, and another 10% is used on oil and natural-gas fields where it is both a down hole lubricant, and a grinding and extraction aid.
Hexasol is also employed as an antifreeze, and as a coupling agent for hydraulic fluids.


That’s why Hexasol is commonly used in many cosmetics, e.g. shampoos, shower gels, and soaps.
Thanks to Hexasol, products are better adapted to the needs of consumers and meet their expectations.
Therefore, the addition of Hexasol can turn an ordinary cosmetic into something that will be used with real pleasure.


In the realm of cosmetics and personal care products, Hexasol functions as a preservative.
Hexasol′s a humectant that aids in skin moisture retention and enhances skin texture and appearance.
Hexasol operates by forming a barrier on the skin to impede moisture loss.


Hexasol is a highly soluble advanced organic solvent, which can be used in the production of metal surface treatment agents, rust and oil removal additives, textile auxiliaries, coatings and latex paints, cosmetics, pesticides, biochemical engineering, photosensitive materials, synthetic perfumes and other fields.


Hexasol is used for pesticide stabilizer, diesel antifreezer, solvent, spicery, disinfectant,fabric penetration agent and coupler , paper and leather processing auxiliary agent, emulsifier, the additive of fuel and lubricant, etc.
Hexasol is mainly used as a solvent or coupling agent.



ALTERNATIVES OF HEXASOL:
*PROPYLENE GLYCOL,
*BUTYLENE GLYCOL,
*GLYCERIN



HOW IS HEXASOL PRODUCED?
Hexasol is formed from the achiral reagents hydrogen and diacetone alcohol.



HOW IS HEXASOL STORED AND DISTRIBUTED?
Hexasol is stored in bulk storage or stainless steel drums and is transported by tank truck.
Hexasol is classed as non-hazardous for air, sea, and road freight but is classed as an irritant.
Hexasol has a specific gravity of 0.925 and a flash point of 93 °C (closed cup).



WHAT IS HEXASOL USED FOR?
The single largest user of Hexasol is the industrial coatings industry which uses approximately 45% of the HGL produced world-wide.
Hexasol is a component in lacquers and varnishes, and is a solvent plasticiser in surface coatings.
Hexasol is also a component in both oil and water- based paints, and in paint strippers.



HEXASOL AT A GLANCE:
*Solvent that produces smooth spreadability and pleasing skin care textures
*Viscosity-reducing properties allow Hexasol to thin out heavy, thick formulations
*Shows up in a wide variety of skin care, hair care, and makeup products
*As a raw material, Hexasol is clear liquid
*Backed by decades of research as a safe ingredient



BENEFITS OF HEXASOL:
Hexasol offers several benefits in various applications, particularly in cosmetics and personal care products:

*Humectant:
Hexasol helps to retain moisture, which is essential for skin and hair health.
Hexasol can keep these products from drying out, ensuring that they remain effective and pleasant to use.

*Solvent:
Hexasol functions as a solvent, helping to dissolve and blend other ingredients in cosmetics and personal care products.
This facilitates the formulation of moisturisers, lotions, and other beauty products.

*Texture Improvement:
Hexasol can enhance the texture of skincare and hair care products, making them smoother and easier to apply.
This contributes to a more luxurious and user-friendly experience.

*Fragrance Fixative:
In the perfume industry, Hexasol is used as a fixative, helping to stabilize and prolong the scent of fragrances.
This ensures that the fragrance remains consistent and long-lasting.

*Skin-Friendly:
Hexasol is considered safe for use in cosmetics and personal care products, as it has low skin irritation potential.
Hexasol is typically well-tolerated by most individuals.

*Versatility:
Its versatility makes Hexasol suitable for a wide range of products, including moisturizers, shampoos, conditioners, and perfumes.



IS HEXASOL VEGAN?
Hexasol is considered to be a vegan ingredient as it is made synethically made from oils and natural gas.
If you are looking for a vegan product, always make sure that the other ingredients in Hexasol are vegan and that the brand is cruelty-free.



SCIENTIFIC FACTS OF HEXASOL:
Butylene Glycol, or 1,3-Butanediol, dissolves most essential oils and synthetic flavoring substances.
Butylene Glycol, Hexasol, Ethoxydiglycol and Dipropylene Glycol are glycols or glycol ethers.
Glycols are a class of alcohols that contain two hydroxyl groups which are also called a diols.



PROPERTIES OF HEXASOL:
*Purity (% by weight) : ≥ 99,5
*Appearance at 20°C : clear liquid free from suspended materials
*Density at 20°C (g/cm3) : 0,920 - 0,923
*Boiling point at 1013 Pa : 197,5°C
*Flash point (closed cup) : 97°C
*Water solubility at 20°c : complete
*Hansen Solubility Parameters at 25°C: δt = 25,2; δd = 15,8; δp = 8,4; δh = 17



WHAT IS HEXASOL USED FOR?
Hexasol serves many functional benefits in skin care, hair care, and cosmetic products.


*Skin care:
Hexasol is primarily used in skin care to improve the sensory feel and texture of the products.
Hexasol also attracts and retains moisture on the surface of the skin, keeping it hydrated and nourished.
Hexasol is often found in products like toners and cleansers


*Hair care:
Hexasol is used as a viscosity agent and solvent to improve the texture and stability of formulations.
Hexasol also acts as an emollient in shampoos and conditioners to provide hydration to the shafts


*Cosmetic products:
Hexasol works to dissolve other ingredients present in a formulation and enhance the texture of the final product.
Since it has low viscosity, Hexasol is a useful ingredient in products like foundations, primers, and concealers



WHAT DOES HEXASOL DO IN A FORMULATION?
*Humectant
*Solvent
*Viscosity controlling



WHAT ARE THE FUNCTIONS OF HEXASOL?
Hexasol is added to cosmetics and skincare products based on its functions as a surfactant, an emulsifier, and a viscosity-reducing agent.

*SURFACTANT
Surfactant is the short term for surface active agents.
Surfactants are compounds that lower the surface tension between two substances.
In skincare products, surfactants work to lift dirt, oil and fats from the skin, allowing them to be washed away.

This is possible because while one end of the surfactant molecule is attracted to water, the other end is attracted to oil.
Thus, surfactants attract the oil, dirt, and other impurities that have accumulated on your skin during the day and wash them away.
Due to these properties, Hexasol can be found in many different cleansers and body washes.


*EMULSIFIER
Hexasol also functions as an emulsifier.
An emulsifier is needed for products that contain both water and oil components, for example, when oils are added to a water-based formula.
When shaking stops, however, the two phases can start to separate.

To address this problem, an emulsifier like Hexasol can be added to the system, which helps the droplets remain dispersed and produces an even and stable formulation.

As an emulsifier, Hexasol consists of a water-loving hydrophilic head and an oil-loving hydrophobic tail.
The hydrophilic head is attracted to the water and the hydrophobic tail to the oil.
Once again, Hexasol reduces the surface tension by positioning itself between the oil and water, which has a stabilizing effect on the product.


*THINNING
Finally, Hexasol functions as a viscosity-reducing agent.
The term viscosity corresponds to the concept of “thickness”, for example, honey has a higher viscosity than water.
As a viscosity-reducing agent, Hexasol works to thin out heavy formulations and create a thinner, more spreadable product.



SAFETY PROFILE OF HEXASOL:
Hexasol is generally considered safe for use in cosmetic products.
Hexasol does not cause skin irritation and sensitization and is not known to be comedogenic.
However, as with any ingredient, some individuals may have an allergic reaction or sensitivity to it, so Hexasol is always recommended to patch test products before use.
Lastly, Hexasol is vegan and can be considered halal, but it is best to check with the supplier.



IS HEXASOL SAFE?
The safety of Hexasol has been assessed by the Cosmetic Ingredient Review Expert Panel.
The Cosmetic Ingredient Review Expert Panel is responsible for the independent evaluation of the safety and efficacy of skincare and cosmetic ingredients.
The Expert Panel evaluated the scientific data and concluded that Hexasol is safe for use in cosmetics and personal care products.



FEATURES OF HEXASOL:
*Solvent,
*intermediate



THE GOOD:
Hexasol helps to improve the texture and feel of skincare and cosmetic formulations.
Hexasol also has an added benefit of acting as a protective barrier for the skin.


THE NOT SO GOOD:
Hexasol can be a mild irritant in high concentrations.


WHO IS HEXASOL FOR?
All skin types except those that have an identified allergy to Hexasol.


SYNERGETIC INGREDIENTS:
Hexasol works well with most ingredients.


KEEP AN EYE ON:
Nothing to keep an eye on here.



ORIGIN OF HEXASOL:
Hexasol is typically synthesized by the reaction of ethylene oxide with n-butanol or by the hydration of 1,5-hexadiene.
Hexasol is later purified by distillation or other methods to obtain the final Hexasol.



PHYSICAL and CHEMICAL PROPERTIES of HEXASOL:
Molecular Weight: 118.174
Exact Mass: 118.17
EC Number: 203-489-0
ICSC Number: 0660
NSC Number: 8098
UN Number: 1993
DSSTox ID: DTXSID5021885
Color/Form: Liquid|Colorless liquid
HScode: 2905399090
PSA: 40.46000
Boiling Point: 197.5°C
Melting Point: -50°C
pH: 7.0

Solubility: Highly soluble in water
Viscosity: Low
XLogP3: 0.00
Appearance: Hexylene glycol is an oily colorless liquid with a mild sweet odor.
Floats and mixes slowly with water.
Density: 0.92 g/cm3
Melting Point:-50 °C
Boiling Point:198 °C @ Press: 760 Torr
Flash Point:93.9±0.0 °C
Refractive Index:1.447
Water Solubility:Miscible
Storage Conditions:Separated from strong oxidants and strong acids.
Vapor Pressure:0.05 mmHg

Vapor Density:
Relative vapour density (air = 1): 4.1
Flammability characteristics: Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Explosive limit: Explosive limits , vol% in air: 1.2-8.1
Odor:Mild sweetish
Henrys Law Constant:
Henry's Law constant = 4.06X10-7 atm-cu m/mol at 25 °C (est)
Experimental Properties:
Dipole moment: 2.8
Heat of formation = -5.3476X10+8 J/kmol
Triple point temperature = 223.15 °C; triple point pressure: 9.5609X10-6 Pa
Hydroxyl radical reaction rate constant = 2.77X10-11 atm-cu m/mol at 25 °C

Air and Water Reactions: Hygroscopic.
Water soluble
Reactive Group:Alcohols and Polyols
Reactivity Profile: HEXYLENE GLYCOL is incompatible with the following:
Strong oxidizers, strong acids.
Autoignition Temperature: 583 °F
Autoignition temp = 579 K|306 °C
Heat of Combustion: Standard net heat of combustion = -3.4356x10+9 J/kmol
Flammable Limits: Flammability limits = 1.3-9 vol%
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Heat of Vaporization: 13.7 kcal/mol at the boiling point
Critical Temperature & Pressure:
Critical temp = 621 K
Critical pressure = 4.01X10+6 Pa

Molecular Weight: 118.17
XLogP3-AA: 0.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 118.099379685
Monoisotopic Mass: 118.099379685
Topological Polar Surface Area: 40.5 Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 68.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical name (CAS): 2-methyl-2,4-pentanediol
CAS number: 107-41-5
Structural formula: CH3–CH(OH)–CH2–C(OH)(CH3)2
Molecular formula: C6H14O2
Molecular weight: 118.18
Melting point: –40°C
Boiling point: 195–200°C
Density at 20°C: 0.920–0.923 g/cm3
Vapour pressure at: 20°C 0.06 hPa
log Pow*: –0.14
CAS number: 107-41-5
EC index number: 603-053-00-3
EC number: 203-489-0
Grade: NF

Hill Formula: C₆H₁₄O₂
Molar Mass: 118.18 g/mol
HS Code: 2926 90 70
Density: 0.922 g/cm3 (20 °C)
Explosion limit: 1 - 9.9 %(V)
Flash point: 94 °C
Ignition temperature: 425 °C
Melting Point: -40 °C
pH value: 6.0 - 8.0 (118.2 g/l, H₂O, 25 °C)
Vapor pressure: 0.03 hPa (20 °C)
Physical state: liquid
Color: colorless
Odor: sweet, mild
Melting point/freezing point:
Melting point/range: -40 °C - lit.

Initial boiling point and boiling range: 197 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 7,4 %(V)
Lower explosion limit: 1,3 %(V)
Flash point: 94 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 6,0 - 8,0 at 118,2 g/l at 25 °C
Solubility:
Easily soluble in cold water.
Soluble in diethyl ether.
Soluble in alcohol, lower aliphatic hydrocarbons.
Soluble in a variety of organic solvents.
Miscible with fatty acids
Specific Gravity 20/20 °C:0.9232

Distillation Range at 760 mm Hg (IP) °C:196.4
Distillation Range at 760 mm Hg (DP) °C:198.2
Purity, % w/w:99.62
Acidity as acetic Acid, % w/w: 0.0010
Water, % w/w: 0.018
Melting point: −40 °C(lit.)
Boiling point: 197 °C(lit.)
Density: 0.925 g/mL at 25 °C(lit.)
vapor density: 4.1 (vs air)
vapor pressure: 0.02 mm Hg ( 20 °C)
refractive index: n20/D 1.427(lit.)
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 36 mPa.s at 20 °C

Water solubility ca.: 118,2 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,58 - (Lit.), Bioaccumulation is not expected.
Vapor pressure: 0,03 hPa at 20 °C
Density: 0,925 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information
Relative vapor density: 4,08 - (Air = 1.0)
Molar Weight: 118.176g/mol
Melting Point: -40 °C
Boiling Point: 196 °C

Flash Point: 93 °C
Density: 0.925
Forms: Liquid (clear)
Chemical formula: C6H14O2
Molar mass: 118.176 g•mol−1
Appearance: colourless liquid
Odor: mild, sweetish
Density: 0.92 g/mL
Melting point: −40 °C (−40 °F; 233 K)
Boiling point: 197 °C (387 °F; 470 K)
Solubility in water: miscible[1]
Vapor pressure: 0.05 mmHg (20°C)
Flash point: 98.3 °C (208.9 °F; 371.4 K)
Explosive limits: 1.3%-7.4%
Appearance: colorless clear liquid (est)
Physical state and Appearance:Liquid.

Odor:Sweetish
Molecular Weight:118.18 g/mole
Color:Colorless
Boiling Point:197 (386.6) - 198° C
Melting Point:-50 - (-58)
Specific Gravity:0.9254 @ 17 C; 0.9234 @ 20 C (Water = 1)
Vapor Pressure: 0.05 mm of Hg (@ 20)
Vapor Density: 4.1 (Air = 1)
Odor Threshold: 50 ppm
Dispersion Properties: See solubility in water, diethyl ether
Flash point: 201 °F
storage temp.: 2-8°C
solubility: H2O: 1 M at 20 °C, clear, colorless
pka: 14.72±0.20(Predicted)
CAS DataBase Reference: 5683-44-3(CAS DataBase Reference)

Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92400 @ 25.00 °C.
Melting Point: -40.00 °C. @ 760.00 mm Hg
Boiling Point: 197.00 to 199.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.096000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.1 ( Air = 1 )
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 0.004 (est)
Soluble in: alcohol
water, 3.256e+004 mg/L @ 25 °C (est)
water, 1.00E+06 mg/L @ 25 °C (exp)
Molecular Weight: 118.2 g/mol
Empirical Formula: C6H14O2

Appearance: Colorless, Liquid
Freezing Point: -50°C (-58.0°F)
Boiling Point: @ 760mm Hg 196°C (385°F)
Flash Point: Closed Cup 96°C (205°F)
Autoignition Temperature: 425°C (797°F)
Density @ 20°C: 0.924 kg/L, 7.71 lb/gal
Vapor Pressure: @ 20°C 0.05 mmHg
Evaporation Rate: (nBuAc = 1) 0.007
Solubility in Water: @ 20°C Miscible
Surface Tension @ 20°C: 33.1 dynes/cm
Refractive Index @ 20°C: 1.426
Viscosity @ 20°C: 38.9 cP
Lower Explosive Limit: 1.0 v/v%
Upper Explosive Limit: 9.9 v/v%
Conductivity @ 20°C: 3x106 pS/m

Dielectric Constant @ 20°C: ≈7.7
Specific Heat @ 20°C: 2.20 kJ/kg/°C
Heat of Vaporization @ normal boiling point: 435 kJ/kg
Heat of Combustion @ 25°C: 29875 kJ/kg
Odor Threshold: 50 ppm
Molecular Weight 118.2 g/mol
Empirical Formula C6H14O2
Appearance Colorless
Liquid
Freezing Point -50°C (-58.0°F)
Boiling Point @ 760mm Hg 196°C (385°F)
Flash Point – Closed Cup 96°C (205°F)
Autoignition Temperature 425°C (797°F)

Density @ 20°C 0.924 kg/L
7.71 lb/gal
Vapor Pressure @ 20°C 0.05 mmHg
Evaporation Rate (nBuAc = 1) 0.007
Solubility in Water @ 20°C Miscible
Surface Tension @ 20°C 33.1 dynes/cm
Refractive Index @ 20°C 1.426
Viscosity @ 20°C 38.9 cP
Lower Explosive Limit 1.0 v/v%
Upper Explosive Limit 9.9 v/v%
Conductivity @ 20°C 3x106 pS/m
Dielectric Constant @ 20°C ≈7.7
Specific Heat @ 20°C 2.20 kJ/kg/°C

Heat of Vaporization @ normal boiling point 435 kJ/kg
Heat of Combustion @ 25°C 29875 kJ/kg
Odor Threshold 50 ppm
CAS NO:107-41-5
EINECS NO:203-489-0
Molecular Formula:C6H14O2
Molecular Weight:118.1742
InChI:InChI=1/C6H14O2/c1-5(7)4-6(2,3)8/h5,7-8H,4H2,1-3H3
Density:0.96g/cm3
Melting Point:-40ºC
Boiling Point:197.5°C at 760 mmHg
Flash Point:93.9°C
Water Solubility:soluble
Vapour Pressure:0.0961mmHg at 25°C

Refractive Rate:n20/D1.427(lit.)
Storage Condition:2-8°C
Appearance:Clear colorless Slightly Viscous Liquid
Odor:Ammonia-like
PH Value:6-8(25ºC,1MinH2O)
Explosive Limit:1-9.9%(V)
Sensitivity:Hygroscopic
Stability: Incompatible with strong oxidizing agents, strong acids,strong reducing agents.
Physical description: Colorless liquid with a mild, sweetish odor.
Boiling point: 388°F
Molecular weight: 118.2
Freezing point/melting point: -58°F (sets to glass)
Vapor pressure: 0.05 mmHg
Flash point: 209°F
Specific gravity: 0.923

Lower explosive limit (LEL): 1.3% (calc)
Upper explosive limit (UEL): 8.1% (calc)
NFPA health rating: 2
NFPA fire rating: 1
NFPA reactivity rating: 0
Appearance: colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92400 @ 25.00 °C.
Melting Point: -40.00 °C. @ 760.00 mm Hg
Boiling Point: 197.00 to 199.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.096000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.1 ( Air = 1 )
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 0.004 (est)
Soluble in: alcohol
water, 3.256e+004 mg/L @ 25 °C (est)
water, 1.00E+06 mg/L @ 25 °C (exp)



FIRST AID MEASURES of HEXASOL:
-Description of first-aid measures:
*General advice
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXASOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXASOL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXASOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 240 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXASOL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Store under inert gas.
Hygroscopic.



STABILITY and REACTIVITY of HEXASOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


HEXASOL HEXYLENE GLYCOL
Hexasol Hexylene Glycol is a clear, colorless liquid chemical compound with the molecular formula C6H14O2.
Hexasol Hexylene Glycol functions as a surfactant, emulsifier, and a viscosity-reducing agent.


CAS Number: 107-41-5
EC Number: 203-489-0
MDL number: MFCD00004547
Chem/IUPAC Name: 2-Methylpentane-2,4-diol
Molecular Formula: C6H14O2 or (CH3)2COHCH2CHOHCH3



2-Methyl-2,4-Pentanediol, 2-Methylpentane-2,4-Diol, Diolane, Hexylene Glycol (2-Methyl-2,4-Pentanediol, Isol, Pinakon, MPD, Hexane-1,2-Diol, (4S)-2-Methylpentane-2,4-Diol, (4R)-2-Methylpentane-2,4-Diol, Hexasol, 2,4-dihydroxy-2-methylpentane, 2-methyl-2,4-pentanediol, 4-methyl-2,4-pentanediol, 2-methylpentane-2,4-diol, 2,4-Dihydroxy-2-methylpentane, 2-Methyl-2,4-pentanediol, 4-Methyl-2,4-pentanediol, 2-Methylpentane-2,4-diol, 2,4-Pentanediol, 2-methyl-, α,α,α'-Trimethyltrimethylene glycol, Diolane, Isol, 1,1,3-Trimethyltrimethylenediol, 2-Methyl-2,4-pentandiol, 2-Methyl-2,4-pentanediol, 2,4-Dihydroxy-2-methylpentane, 4-Methyl-2,4-pentanediol, 2-Methyl pentane-2,4-diol, 2-Methylpentan-2,4-diol, Pinakon, 4-Methyl-2,4-pentanediole, (.+/-.)-2-Methyl-2,4-pentanediol, NSC 8098, Isophthalic acid, 2-Methyl-2,4-pentanediol1,1,3-Trimethyltrimethylenediol2,4-Dihydroxy-2-methylpentane2-Methyl pentane-2,4-diol4-Methyl-2,4-pentanediolTrimethyltrimethylene glycolDiolaneIsolPinakonHexG, (2,4-dihydroxy-2-methylpentane, 2,4-pentanediol, 2-methyl-, 2-methylpentane-2,4-diol, 4-methyl-2,4-pentanediol, alpha,alpha,alpha’-trimethyltrimethylene glycol, diolane, hexylene glycol, isol, pinakon, 2,4-Pentanediol,2-methyl-, 2-Methyl-2,4-pentanediol, 2,4-Dihydroxy-2-methylpentane, Diolane, Hexylene glycol, Isol, α,α,α′-Trimethyltrimethylene glycol, 1,1,3-Trimethyltrimethylenediol, MPD, (±)-2-Methyl-2,4-pentanediol, NSC 8098, Hexasol, Isohexanediol, 99113-75-4, 2-furanmethanol, 2-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, Hexylene glycol, 2-METHYL-2,4-PENTANEDIOL, 107-41-5, 2-Methylpentane-2,4-diol, Diolane, Pinakon, 2,4-Pentanediol, 2-methyl-, 2,4-Dihydroxy-2-methylpentane, Isol, 4-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, Caswell No. 574, 2-Methyl pentane-2,4-diol, 2-Methyl-2,4-pentandiol, hexyleneglycol, HSDB 1126, UNII-KEH0A3F75J, (+-)-2-Methyl-2,4-pentanediol, NSC 8098, NSC-8098, EINECS 203-489-0, KEH0A3F75J, alpha,alpha,alpha'-Trimethyltrimethylene glycol, EPA Pesticide Chemical Code 068601, BRN 1098298, 1,3-dimethyl-3-hydroxybutanol, CCRIS 9439, DTXSID5021885, CHEBI:62995, AI3-00919, Hexylene glycol [NF], 1,3,3-trimethyl-1,3-propanediol, TRACID RUBINE 5BL, DTXCID101885, EC 203-489-0, 1,1,3-trimethyl-1,3-propanediol, 4-01-00-02565 (Beilstein Handbook Reference), Hexylene glycol (NF), 7-MethylAtracuriumDimesylate(MixtureofDiastereomers), MPD, CAS-107-41-5, 2-Methylpentan-2,4-diol, 2-Methyl-pentane-2,4-diol, 64229-01-2, MFCD00004547, Hexylene glycol, 99%, R-(-)-2-METHYL-2,4-PENTANEDIOL, 2methyl-2,4-pentanediol, Hexylene glycol, >=99%, Hexylene glycol, 99.5%, SCHEMBL19379, 1,3-Trimethyltrimethylenediol, CHEMBL2104293, NSC8098, (?)-2-Methyl-2,4-pentanediol, SVTBMSDMJJWYQN-UHFFFAOYSA-N, HMS3264E19, HY-B0903, Hexylene glycol, analytical standard, Tox21_201975, Tox21_302818, s3588, AKOS015901459, CCG-213719, WLN: QY1 & 1XQ1 & 1, NCGC00249143-01, NCGC00256494-01, NCGC00259524-01, AC-13749, AS-58339, Hexylene glycol, BioXtra, >=99% (GC), (+/-)-2-Methyl-2,4-pentanediol, MPD, FT-0605050, FT-0605756, FT-0613069, Hexylene glycol, puriss., >=99.0% (GC), M0384, (S)-(-)-2-METHYL-2,4-PENTANEDIOL, .alpha.,.alpha.'-Trimethyltrimethylene glycol, Hexylene glycol, BioUltra, >=99.0% (GC), D04439, EN300-170052, AB01563179_01, J-640306, J-660006, Q2792203, W-108748, Z1255485267, Hexylene glycol, United States Pharmacopeia (USP) Reference Standard, Diolane, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, MPD, MVD, FP17780, NSC 66498, Einecs 227-150-, 3-Methylpentanediol-2,4, 2-METHYLPENTANE-2,4-DIOL, 3-METHYL-2,4-PENTANEDIOL, 3-methyl-pentane-2,4-diol, 2,4-Pentanediol, 3-methyl-, HGL, Diolane, Isol, Pinakon, 1,1,3-Trimethyl-Triethylenediol, Diacetone Glycol, Methylamilene Glycol, 2,4-Dihydroxy-2- Methyl-Penthane, 2-Methyl-Penthane-2,4-Diol., (+-)-2-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, 2,4-Pentanediol, 2-methyl-, 2-Methyl pentane-2,4-diol, 2-Methyl-2,4-pentanediol, 4-Methyl-2,4-pentanediol, Diolane, Hexylene glycol, Isol, Pinakon, alpha,alpha,alpha'-Trimethyltrimethylene glycol, HGL, 1, 1, 3-Trimethyl-Triethylenediol, Diacetone Glycol, Methylamilene Glycol, 2, 4-Dihydroxy-2-Methyl-Penthane, 2-Methyl-Penthane-2, 4-Diol, 2-Hexyl-1,3-dioxolan-2-one, Hexylene Glycol, HG, 2,4-Dihydroxy-2-methylpentane, 2-Methyl-2,4-, pentanediol, 2-Methylpentane-2,4-diol, Pentane-2,4-, diol, 2-methyl,



Hexasol Hexylene Glycol, from Solvay, is an oxygenated solvent derived from acetone which has two alcohol functions.
This speciality ingredient, Hexasol Hexylene Glycol, demonstrates a low evaporation rate and is completely miscible with water.
Hexasol Hexylene Glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.


Hexasol Hexylene Glycol has the chemical formula C6H14O2 and is fully miscible in water.
Hexasol Hexylene Glycol is an ingredient used in skincare and cosmetic products to help improve the texture and sensory feel of the formulation.
Hexasol Hexylene Glycol functions as a surfactant, emulsifier, and a viscosity-reducing agent.


Hexasol Hexylene Glycol, also known as 2-Methyl-2,4-pentanediol, is an organic compound that can be classified as a glycol.
Glycols are a class of alcohols that contain two hydroxyl groups, which can also be called a diols.
Hexasol Hexylene Glycol is a clear, hygroscopic liquid with a mild, sweet odor.


Hexasol Hexylene Glycol is most often synthetically produced.
Hexasol Hexylene Glycol is manufactured by the condensation of 2 molecules of acetone to produce diacetone alcohol, which is further hydrogenated to produce Hexasol Hexylene Glycol.


This is then purified.
Hexasol Hexylene Glycol is a clear, colorless liquid chemical compound with the molecular formula C6H14O2.
Hexasol Hexylene Glycol belongs to a class of chemicals known as glycols, which are often used as solvents, humectants, and chemical intermediates in various industrial applications.


Hexasol Hexylene Glycol is commonly used in the cosmetic and personal care industry, where it functions as a solvent and a humectant in products like moisturisers, lotions, and hair care products.
Hexasol Hexylene Glycol helps to maintain moisture and improve the texture of these products.


Hexasol Hexylene Glycol is considered safe for use in cosmetics when used in accordance with regulations and guidelines.
Hexasol Hexylene Glycol is a chemical compound used in various industries, including cosmetics and personal care products.
Hexasol Hexylene Glycol serves as a solvent and a humectant in these products, helping to retain moisture and improve their texture.


Additionally, Hexasol Hexylene Glycol has applications in perfumes, as a fragrance fixative, and in the production of various chemicals and coatings.
Hexasol Hexylene Glycol is considered safe for use in cosmetics when used in compliance with regulations and guidelines.
Hexasol Hexylene Glycol is a diol (with two hydroxy groups at 2 and 4 positions), a colorless liquid with a mildly sweet odor and oily consistency.


In nature, Hexasol Hexylene Glycol is found in the tobacco plant (Nicotiana tabacum).
For industrial purposes Hexasol Hexylene Glycol is formed from the achiral reagents, diacetone alcohol, and hydrogen, producing equal amounts of enantiomeric products.


Commercial Hexasol Hexylene Glycol contains > 99% 2-methyl-2,4-pentanediol and is described as a racemic mixture containing equal amounts of two enantiomers.
Hexasol Hexylene Glycol is a small molecular weight surfactant.


Hexasol Hexylene Glycol is famous for its excellent solvency among a wide variety of materials and is popular in skin care formulas due to its ability to improve the texture.
Hexasol Hexylene Glycol has viscosity-reducing properties that allow it to thin out heavy, thick formulations and produce smooth spreadability.


Studies indicate Hexasol Hexylene Glycol also exhibits antimicrobial properties.
Hexasol Hexylene Glycol also goes by its chemical compound name: 2-Methyl-2,4-pentanediol.
As a raw material, Hexasol Hexylene Glycol is a clear liquid.


Similar to other glycols, Hexasol Hexylene Glycol's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable.
Hexasol Hexylene Glycol is a synthetic substance added to many cosmetics.


Hexasol Hexylene Glycol is an aroma compound and has a preservative effect.
At the same time, Hexasol Hexylene Glycol is also a cleaning agent and detergent.
The most important, however, is the emulsifying property of this glycol.


It is thanks to this that Hexasol Hexylene Glycol has an influence on the consistency of the product.
Hexasol Hexylene Glycol is safe for pregnant women and does not cause allergies.
Hexasol Hexylene Glycol is a biodegradable, colorless liquid that is miscible with water and mainly used as a solvent or coupling agent


Hexasol Hexylene Glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.
Hexasol Hexylene Glycol is fully miscible in water and has the chemical formula C6H14O2.
Hexasol Hexylene Glycol is a compound that appears in a large number of products that are used commercially and industrially.


Hexasol Hexylene Glycol is a clear, practically colorless, liquid.
Hexasol Hexylene Glycol is characterized as a clear, colorless, and odorless liquid that finds extensive use in numerous industries, such as cosmetics and personal care products.


Hexasol Hexylene Glycol′s a category of glycol often utilized as a solvent, humectant, and an agent to control viscosity.
Hexasol Hexylene Glycol, alternative to PG or DEG or MEG in paint formulation in lowering total VOC content.
Hexasol Hexylene Glycol is a small molecular weight surfactant, widely used as an industrial coating solvent, does not cause adverse health or environmental effects.


Hexasol Hexylene Glycol is an oily colorless liquid with a mild sweet odor.
Hexasol Hexylene Glycol floats and mixes slowly with water.
Hexasol Hexylene Glycol is an oily colorless liquid with a mild sweet odor.


Hexasol Hexylene Glycol floats and mixes slowly with water.
|2-methylpentane-2,4-diol is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).
Hexasol Hexylene Glycol is a clear, colorless liquid.


The principal end uses of Hexasol Hexylene Glycol include industrial solvent, chemical intermediate, cosmetics, excipient in pharmaceuticals, paints and coatings.
Hexasol Hexylene Glycol is available in technical grade and NF grade.


Hexasol Hexylene Glycol is an oxygenated solvent derived from acetone which has two alcohol functions.
Hexasol Hexylene Glycol has a low evaporation rate and it is completely miscible with water.
Hexasol Hexylene Glycol is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.


Hexasol Hexylene Glycol is 2-methyl-2,4-pentanediol.
Hexasol Hexylene Glycol is used as coupling agent.
Hexasol Hexylene Glycol offers low flammability and low evaporation rate.


Hexasol Hexylene Glycol possesses low surface tension.
Hexasol Hexylene Glycol exhibits very good solvency.
Hexasol Hexylene Glycol is a clear, colorless liquid that is used in many personal care and cosmetic formulations.


Hexasol Hexylene Glycol largely acts as a solvent, humectant, and viscosity agent.
Decades of research have established Hexasol Hexylene Glycol as a safe and effective ingredient.
Hexasol Hexylene Glycol dissolves other ingredients in a product and enhances its stability and texture.


Hexasol Hexylene Glycol also has a low viscosity that makes it easier to incorporate.
The chemical formula of Hexasol Hexylene Glycol is C6H14O2.
Hexasol Hexylene Glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.


Hexasol Hexylene Glycol is fully miscible in water and has the chemical formula C6H14O2.
Hexasol Hexylene Glycol is a compound that appears in a large number of products that are used commercially and industrially
Hexasol Hexylene Glycol has a low evaporation rate and it is completely miscible with water.



USES and APPLICATIONS of HEXASOL HEXYLENE GLYCOL:
Hexasol Hexylene Glycol is a compound that appears in a large number of products that are used commercially and industrially.
Hexasol Hexylene Glycol is used widely across skincare, hair care, and makeup to enhance spreadability, thin out overly thick formulas, and ensure actives are fully dissolved and dispersed.


Hexasol Hexylene Glycol also has some antimicrobial effect and can enhance the efficacy of certain preservatives.
Hexasol Hexylene Glycol is used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products at concentrations ranging from 0.1% – 25%.


Hexasol Hexylene Glycol as a surfactant helps to cleanse and moisturize the skin as well as thinning out the formulation to improve absorption, texture and allow other ingredients to work better.
Hexasol Hexylene Glycol is also used as a chemical intermediate in chemical syntheses, downhole lubricant for natural gas and oil fields, hydraulic fluid, antifreeze, fuel additive, the solvent in dyes and inks, leather and textile processing, industrial and household cleaners, and in cosmetics.


The largest end use for Hexasol Hexylene Glycol is in industrial coatings, as a solvent plasticizer in varnishes, lacquers, paints, and paint strippers, accounting for about 45% of the total production.
Hexasol Hexylene Glycol is often used in preservative blends that contain phenoxyethanol because it boosts the efficacy of this preservative, allowing lower amounts to be used, which reduces the risk skin will have a sensitised response.


Hexasol Hexylene Glycol is mainly used as a solvent or coupling agent.
Hexasol Hexylene Glycol is a potential substitute for glycol ethers.
Hexasol Hexylene Glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.


Hexasol Hexylene Glycol can also be used as a building block in chemical synthesis.
In addition to skin care, Hexasol Hexylene Glycol is used in other beauty products including hair care and makeup.
Hexasol Hexylene Glycol has been backed as a safe ingredient for decades with reported concentrations up to 25% in personal care products (though most skin care formulas use much lower amounts than that, especially in preservative blends).


That’s why Hexasol Hexylene Glycol is commonly used in many cosmetics, e.g. shampoos, shower gels, and soaps.
Thanks to Hexasol Hexylene Glycol, products are better adapted to the needs of consumers and meet their expectations.
Therefore, the addition of Hexasol Hexylene Glycol can turn an ordinary cosmetic into something that will be used with real pleasure.


Hexasol Hexylene Glycol is a cosmetic material for FDA regulated product use.
In cosmetics and personal care products, these ingredients are used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.


Moreover, Hexasol Hexylene Glycol acts as a reagent in the synthesis of diverse chemicals.
With regard to scientific research applications, Hexasol Hexylene Glycol serves as a solvent to extract an array of compounds from plant and animal tissues.
Hexasol Hexylene Glycol′s also employed as a reagent in the creation of various chemicals, including agrochemicals and fragrances.


In the realm of cosmetics and personal care products, Hexasol Hexylene Glycol functions as a preservative.
Hexasol Hexylene Glycol′s a humectant that aids in skin moisture retention and enhances skin texture and appearance.
Hexasol Hexylene Glycol operates by forming a barrier on the skin to impede moisture loss.


Additionally, Hexasol Hexylene Glycol helps to decrease the skin′s surface tension, thereby facilitating the penetration of other ingredients into the skin.
Hexasol Hexylene Glycol is mainly used as a solvent or coupling agent.
Hexasol Hexylene Glycol is a potential substitute for glycol ethers.


Hexasol Hexylene Glycol is a highly soluble advanced organic solvent, which can be used in the production of metal surface treatment agents, rust and oil removal additives, textile auxiliaries, coatings and latex paints, cosmetics, pesticides, biochemical engineering, photosensitive materials, synthetic perfumes and other fields.


Hexasol Hexylene Glycol is used for pesticide stabilizer, diesel antifreezer, solvent, spicery, disinfectant,fabric penetration agent and coupler , paper and leather processing auxiliary agent, emulsifier, the additive of fuel and lubricant, etc.
Hexasol Hexylene Glycol is mainly used as a solvent or coupling agent.


Hexasol Hexylene Glycol is a potential substitute for glycol ethers.
Hexasol Hexylene Glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexasol Hexylene Glycol can also be used as a building block in chemical synthesis.


Hexasol Hexylene Glycol is also used as a chemical intermediate, which accounts for approximately 20% of its consumption, and another 10% is used on oil and natural-gas fields where it is both a down hole lubricant, and a grinding and extraction aid.
Hexasol Hexylene Glycol is also employed as an antifreeze, and as a coupling agent for hydraulic fluids.


Hexasol Hexylene Glycol is a moisturising, and setting, agent in the manufacture of textiles and can also be found in the cosmetics industry where it is a component of fragrances and bath, hair, and soap preparations.
Hexasol Hexylene Glycol also has a role as a wetting agent in pesticide formulations and is a solvent in the preparation of dyes.


Hexasol Hexylene Glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexasol Hexylene Glycol can also be used as a building block in chemical synthesis.
Hexasol Hexylene Glycol is mainly used as a solvent or coupling agent.



WHAT IS HEXASOL HEXYLENE GLYCOL USED FOR?
Hexasol Hexylene Glycol serves many functional benefits in skin care, hair care, and cosmetic products.

*Skin care:
Hexasol Hexylene Glycol is primarily used in skin care to improve the sensory feel and texture of the products.
Hexasol Hexylene Glycol also attracts and retains moisture on the surface of the skin, keeping it hydrated and nourished.
Hexasol Hexylene Glycol is often found in products like toners and cleansers


*Hair care:
Hexasol Hexylene Glycol is used as a viscosity agent and solvent to improve the texture and stability of formulations.
Hexasol Hexylene Glycol also acts as an emollient in shampoos and conditioners to provide hydration to the shafts


*Cosmetic products:
Hexasol Hexylene Glycol works to dissolve other ingredients present in a formulation and enhance the texture of the final product.
Since it has low viscosity, Hexasol Hexylene Glycol is a useful ingredient in products like foundations, primers, and concealers



ORIGIN OF HEXASOL HEXYLENE GLYCOL:
Hexasol Hexylene Glycol is typically synthesized by the reaction of ethylene oxide with n-butanol or by the hydration of 1,5-hexadiene.
Hexasol Hexylene Glycol is later purified by distillation or other methods to obtain the final Hexasol Hexylene Glycol.



WHAT DOES HEXASOL HEXYLENE GLYCOL DO IN A FORMULATION?
*Humectant
*Solvent
*Viscosity controlling



SAFETY PROFILE OF HEXASOL HEXYLENE GLYCOL:
Hexasol Hexylene Glycol is generally considered safe for use in cosmetic products.
Hexasol Hexylene Glycol does not cause skin irritation and sensitization and is not known to be comedogenic.
However, as with any ingredient, some individuals may have an allergic reaction or sensitivity to it, so Hexasol Hexylene Glycol is always recommended to patch test products before use.
Lastly, Hexasol Hexylene Glycol is vegan and can be considered halal, but it is best to check with the supplier.



ALTERNATIVES OF HEXASOL HEXYLENE GLYCOL:
*PROPYLENE GLYCOL,
*BUTYLENE GLYCOL,
*GLYCERIN



HOW IS HEXASOL HEXYLENE GLYCOL PRODUCED?
Hexasol Hexylene Glycol is formed from the achiral reagents hydrogen and diacetone alcohol.



HOW IS HEXASOL HEXYLENE GLYCOL STORED AND DISTRIBUTED?
Hexasol Hexylene Glycol is stored in bulk storage or stainless steel drums and is transported by tank truck.
Hexasol Hexylene Glycol is classed as non-hazardous for air, sea, and road freight but is classed as an irritant.
Hexasol Hexylene Glycol has a specific gravity of 0.925 and a flash point of 93 °C (closed cup).



WHAT IS HEXASOL HEXYLENE GLYCOL USED FOR?
The single largest user of Hexasol Hexylene Glycol is the industrial coatings industry which uses approximately 45% of the HGL produced world-wide.
Hexasol Hexylene Glycol is a component in lacquers and varnishes, and is a solvent plasticiser in surface coatings.
Hexasol Hexylene Glycol is also a component in both oil and water- based paints, and in paint strippers.



HEXASOL HEXYLENE GLYCOL AT A GLANCE:
*Solvent that produces smooth spreadability and pleasing skin care textures
*Viscosity-reducing properties allow Hexasol Hexylene Glycol to thin out heavy, thick formulations
*Shows up in a wide variety of skin care, hair care, and makeup products
*As a raw material, Hexasol Hexylene Glycol is clear liquid
*Backed by decades of research as a safe ingredient



BENEFITS OF HEXASOL HEXYLENE GLYCOL:
Hexasol Hexylene Glycol offers several benefits in various applications, particularly in cosmetics and personal care products:

*Humectant:
Hexasol Hexylene Glycol helps to retain moisture, which is essential for skin and hair health.
Hexasol Hexylene Glycol can keep these products from drying out, ensuring that they remain effective and pleasant to use.

*Solvent:
Hexasol Hexylene Glycol functions as a solvent, helping to dissolve and blend other ingredients in cosmetics and personal care products.
This facilitates the formulation of moisturisers, lotions, and other beauty products.

*Texture Improvement:
Hexasol Hexylene Glycol can enhance the texture of skincare and hair care products, making them smoother and easier to apply.
This contributes to a more luxurious and user-friendly experience.

*Fragrance Fixative:
In the perfume industry, Hexasol Hexylene Glycol is used as a fixative, helping to stabilize and prolong the scent of fragrances.
This ensures that the fragrance remains consistent and long-lasting.

*Skin-Friendly:
Hexasol Hexylene Glycol is considered safe for use in cosmetics and personal care products, as it has low skin irritation potential.
Hexasol Hexylene Glycol is typically well-tolerated by most individuals.

*Versatility:
Its versatility makes Hexasol Hexylene Glycol suitable for a wide range of products, including moisturizers, shampoos, conditioners, and perfumes.



IS HEXASOL HEXYLENE GLYCOL SAFE?
The safety of Hexasol Hexylene Glycol has been assessed by the Cosmetic Ingredient Review Expert Panel.
The Cosmetic Ingredient Review Expert Panel is responsible for the independent evaluation of the safety and efficacy of skincare and cosmetic ingredients.
The Expert Panel evaluated the scientific data and concluded that Hexasol Hexylene Glycol is safe for use in cosmetics and personal care products.



FEATURES OF HEXASOL HEXYLENE GLYCOL:
*Solvent,
*intermediate



THE GOOD:
Hexasol Hexylene Glycol helps to improve the texture and feel of skincare and cosmetic formulations.
Hexasol Hexylene Glycol also has an added benefit of acting as a protective barrier for the skin.


THE NOT SO GOOD:
Hexasol Hexylene Glycol can be a mild irritant in high concentrations.


WHO IS HEXASOL HEXYLENE GLYCOL FOR?
All skin types except those that have an identified allergy to Hexasol Hexylene Glycol.


SYNERGETIC INGREDIENTS:
Hexasol Hexylene Glycol works well with most ingredients.


KEEP AN EYE ON:
Nothing to keep an eye on here.



WHAT ARE THE FUNCTIONS OF HEXASOL HEXYLENE GLYCOL?
Hexasol Hexylene Glycol is added to cosmetics and skincare products based on its functions as a surfactant, an emulsifier, and a viscosity-reducing agent.

*SURFACTANT
Surfactant is the short term for surface active agents.
Surfactants are compounds that lower the surface tension between two substances.
In skincare products, surfactants work to lift dirt, oil and fats from the skin, allowing them to be washed away.

This is possible because while one end of the surfactant molecule is attracted to water, the other end is attracted to oil.
Thus, surfactants attract the oil, dirt, and other impurities that have accumulated on your skin during the day and wash them away.
Due to these properties, Hexasol Hexylene Glycol can be found in many different cleansers and body washes.


*EMULSIFIER
Hexasol Hexylene Glycol also functions as an emulsifier.
An emulsifier is needed for products that contain both water and oil components, for example, when oils are added to a water-based formula.

According to EFEMA, when water and oil are mixed together and vigorously shaken, a dispersion of oil droplets in water is formed.
When shaking stops, however, the two phases can start to separate.

To address this problem, an emulsifier like Hexasol Hexylene Glycol can be added to the system, which helps the droplets remain dispersed and produces an even and stable formulation.

As an emulsifier, Hexasol Hexylene Glycol consists of a water-loving hydrophilic head and an oil-loving hydrophobic tail.
The hydrophilic head is attracted to the water and the hydrophobic tail to the oil.
Once again, Hexasol Hexylene Glycol reduces the surface tension by positioning itself between the oil and water, which has a stabilizing effect on the product.


*THINNING
Finally, Hexasol Hexylene Glycol functions as a viscosity-reducing agent.
The term viscosity corresponds to the concept of “thickness”, for example, honey has a higher viscosity than water.
As a viscosity-reducing agent, Hexasol Hexylene Glycol works to thin out heavy formulations and create a thinner, more spreadable product.



IS HEXASOL HEXYLENE GLYCOL VEGAN?
Hexasol Hexylene Glycol is considered to be a vegan ingredient as it is made synethically made from oils and natural gas.
If you are looking for a vegan product, always make sure that the other ingredients in Hexasol Hexylene Glycol are vegan and that the brand is cruelty-free.



SCIENTIFIC FACTS OF HEXASOL HEXYLENE GLYCOL:
Butylene Glycol, or 1,3-Butanediol, dissolves most essential oils and synthetic flavoring substances.
Butylene Glycol, Hexasol Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are glycols or glycol ethers.
Glycols are a class of alcohols that contain two hydroxyl groups which are also called a diols.



PROPERTIES OF HEXASOL HEXYLENE GLYCOL:
*Purity (% by weight) : ≥ 99,5
*Appearance at 20°C : clear liquid free from suspended materials
*Density at 20°C (g/cm3) : 0,920 - 0,923
*Boiling point at 1013 Pa : 197,5°C
*Flash point (closed cup) : 97°C
*Water solubility at 20°c : complete
*Hansen Solubility Parameters at 25°C: δt = 25,2; δd = 15,8; δp = 8,4; δh = 17



PHYSICAL and CHEMICAL PROPERTIES of HEXASOL HEXYLENE GLYCOL:
Molecular Weight: 118.174
Exact Mass: 118.17
EC Number: 203-489-0
ICSC Number: 0660
NSC Number: 8098
UN Number: 1993
DSSTox ID: DTXSID5021885
Color/Form: Liquid|Colorless liquid
HScode: 2905399090
PSA: 40.46000
Boiling Point: 197.5°C
Melting Point: -50°C
pH: 7.0

Solubility: Highly soluble in water
Viscosity: Low
XLogP3: 0.00
Appearance: Hexylene glycol is an oily colorless liquid with a mild sweet odor.
Floats and mixes slowly with water.
Density: 0.92 g/cm3
Melting Point:-50 °C
Boiling Point:198 °C @ Press: 760 Torr
Flash Point:93.9±0.0 °C
Refractive Index:1.447
Water Solubility:Miscible
Storage Conditions:Separated from strong oxidants and strong acids.
Vapor Pressure:0.05 mmHg

Vapor Density:
Relative vapour density (air = 1): 4.1
Flammability characteristics: Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Explosive limit: Explosive limits , vol% in air: 1.2-8.1
Odor:Mild sweetish
Henrys Law Constant:
Henry's Law constant = 4.06X10-7 atm-cu m/mol at 25 °C (est)
Experimental Properties:
Dipole moment: 2.8
Heat of formation = -5.3476X10+8 J/kmol
Triple point temperature = 223.15 °C; triple point pressure: 9.5609X10-6 Pa
Hydroxyl radical reaction rate constant = 2.77X10-11 atm-cu m/mol at 25 °C

Air and Water Reactions: Hygroscopic.
Water soluble
Reactive Group:Alcohols and Polyols
Reactivity Profile: HEXYLENE GLYCOL is incompatible with the following:
Strong oxidizers, strong acids.
Autoignition Temperature: 583 °F
Autoignition temp = 579 K|306 °C
Heat of Combustion: Standard net heat of combustion = -3.4356x10+9 J/kmol
Flammable Limits: Flammability limits = 1.3-9 vol%
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Heat of Vaporization: 13.7 kcal/mol at the boiling point
Critical Temperature & Pressure:
Critical temp = 621 K
Critical pressure = 4.01X10+6 Pa

Molecular Weight: 118.17
XLogP3-AA: 0.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 118.099379685
Monoisotopic Mass: 118.099379685
Topological Polar Surface Area: 40.5 Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 68.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical name (CAS): 2-methyl-2,4-pentanediol
CAS number: 107-41-5
Structural formula: CH3–CH(OH)–CH2–C(OH)(CH3)2
Molecular formula: C6H14O2
Molecular weight: 118.18
Melting point: –40°C
Boiling point: 195–200°C
Density at 20°C: 0.920–0.923 g/cm3
Vapour pressure at: 20°C 0.06 hPa
log Pow*: –0.14
CAS number: 107-41-5
EC index number: 603-053-00-3
EC number: 203-489-0
Grade: NF

Hill Formula: C₆H₁₄O₂
Molar Mass: 118.18 g/mol
HS Code: 2926 90 70
Density: 0.922 g/cm3 (20 °C)
Explosion limit: 1 - 9.9 %(V)
Flash point: 94 °C
Ignition temperature: 425 °C
Melting Point: -40 °C
pH value: 6.0 - 8.0 (118.2 g/l, H₂O, 25 °C)
Vapor pressure: 0.03 hPa (20 °C)
Physical state: liquid
Color: colorless
Odor: sweet, mild
Melting point/freezing point:
Melting point/range: -40 °C - lit.

Initial boiling point and boiling range: 197 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 7,4 %(V)
Lower explosion limit: 1,3 %(V)
Flash point: 94 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 6,0 - 8,0 at 118,2 g/l at 25 °C
Solubility:
Easily soluble in cold water.
Soluble in diethyl ether.
Soluble in alcohol, lower aliphatic hydrocarbons.
Soluble in a variety of organic solvents.
Miscible with fatty acids
Specific Gravity 20/20 °C:0.9232

Distillation Range at 760 mm Hg (IP) °C:196.4
Distillation Range at 760 mm Hg (DP) °C:198.2
Purity, % w/w:99.62
Acidity as acetic Acid, % w/w: 0.0010
Water, % w/w: 0.018
Melting point: −40 °C(lit.)
Boiling point: 197 °C(lit.)
Density: 0.925 g/mL at 25 °C(lit.)
vapor density: 4.1 (vs air)
vapor pressure: 0.02 mm Hg ( 20 °C)
refractive index: n20/D 1.427(lit.)
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 36 mPa.s at 20 °C

Water solubility ca.: 118,2 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,58 - (Lit.), Bioaccumulation is not expected.
Vapor pressure: 0,03 hPa at 20 °C
Density: 0,925 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information
Relative vapor density: 4,08 - (Air = 1.0)
Molar Weight: 118.176g/mol
Melting Point: -40 °C
Boiling Point: 196 °C

Flash Point: 93 °C
Density: 0.925
Forms: Liquid (clear)
Chemical formula: C6H14O2
Molar mass: 118.176 g·mol−1
Appearance: colourless liquid
Odor: mild, sweetish
Density: 0.92 g/mL
Melting point: −40 °C (−40 °F; 233 K)
Boiling point: 197 °C (387 °F; 470 K)
Solubility in water: miscible[1]
Vapor pressure: 0.05 mmHg (20°C)
Flash point: 98.3 °C (208.9 °F; 371.4 K)
Explosive limits: 1.3%-7.4%
Appearance: colorless clear liquid (est)
Physical state and Appearance:Liquid.

Odor:Sweetish
Molecular Weight:118.18 g/mole
Color:Colorless
Boiling Point:197 (386.6) - 198° C
Melting Point:-50 - (-58)
Specific Gravity:0.9254 @ 17 C; 0.9234 @ 20 C (Water = 1)
Vapor Pressure: 0.05 mm of Hg (@ 20)
Vapor Density: 4.1 (Air = 1)
Odor Threshold: 50 ppm
Dispersion Properties: See solubility in water, diethyl ether
Flash point: 201 °F
storage temp.: 2-8°C
solubility: H2O: 1 M at 20 °C, clear, colorless
pka: 14.72±0.20(Predicted)
CAS DataBase Reference: 5683-44-3(CAS DataBase Reference)

Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92400 @ 25.00 °C.
Melting Point: -40.00 °C. @ 760.00 mm Hg
Boiling Point: 197.00 to 199.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.096000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.1 ( Air = 1 )
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 0.004 (est)
Soluble in: alcohol
water, 3.256e+004 mg/L @ 25 °C (est)
water, 1.00E+06 mg/L @ 25 °C (exp)
Molecular Weight: 118.2 g/mol
Empirical Formula: C6H14O2

Appearance: Colorless, Liquid
Freezing Point: -50°C (-58.0°F)
Boiling Point: @ 760mm Hg 196°C (385°F)
Flash Point: Closed Cup 96°C (205°F)
Autoignition Temperature: 425°C (797°F)
Density @ 20°C: 0.924 kg/L, 7.71 lb/gal
Vapor Pressure: @ 20°C 0.05 mmHg
Evaporation Rate: (nBuAc = 1) 0.007
Solubility in Water: @ 20°C Miscible
Surface Tension @ 20°C: 33.1 dynes/cm
Refractive Index @ 20°C: 1.426
Viscosity @ 20°C: 38.9 cP
Lower Explosive Limit: 1.0 v/v%
Upper Explosive Limit: 9.9 v/v%
Conductivity @ 20°C: 3x106 pS/m

Dielectric Constant @ 20°C: ≈7.7
Specific Heat @ 20°C: 2.20 kJ/kg/°C
Heat of Vaporization @ normal boiling point: 435 kJ/kg
Heat of Combustion @ 25°C: 29875 kJ/kg
Odor Threshold: 50 ppm
Molecular Weight 118.2 g/mol
Empirical Formula C6H14O2
Appearance Colorless
Liquid
Freezing Point -50°C (-58.0°F)
Boiling Point @ 760mm Hg 196°C (385°F)
Flash Point – Closed Cup 96°C (205°F)
Autoignition Temperature 425°C (797°F)

Density @ 20°C 0.924 kg/L
7.71 lb/gal
Vapor Pressure @ 20°C 0.05 mmHg
Evaporation Rate (nBuAc = 1) 0.007
Solubility in Water @ 20°C Miscible
Surface Tension @ 20°C 33.1 dynes/cm
Refractive Index @ 20°C 1.426
Viscosity @ 20°C 38.9 cP
Lower Explosive Limit 1.0 v/v%
Upper Explosive Limit 9.9 v/v%
Conductivity @ 20°C 3x106 pS/m
Dielectric Constant @ 20°C ≈7.7
Specific Heat @ 20°C 2.20 kJ/kg/°C

Heat of Vaporization @ normal boiling point 435 kJ/kg
Heat of Combustion @ 25°C 29875 kJ/kg
Odor Threshold 50 ppm
CAS NO:107-41-5
EINECS NO:203-489-0
Molecular Formula:C6H14O2
Molecular Weight:118.1742
InChI:InChI=1/C6H14O2/c1-5(7)4-6(2,3)8/h5,7-8H,4H2,1-3H3
Density:0.96g/cm3
Melting Point:-40ºC
Boiling Point:197.5°C at 760 mmHg
Flash Point:93.9°C
Water Solubility:soluble
Vapour Pressure:0.0961mmHg at 25°C

Refractive Rate:n20/D1.427(lit.)
Storage Condition:2-8°C
Appearance:Clear colorless Slightly Viscous Liquid
Odor:Ammonia-like
PH Value:6-8(25ºC,1MinH2O)
Explosive Limit:1-9.9%(V)
Sensitivity:Hygroscopic
Stability: Incompatible with strong oxidizing agents, strong acids,strong reducing agents.
Physical description: Colorless liquid with a mild, sweetish odor.
Boiling point: 388°F
Molecular weight: 118.2
Freezing point/melting point: -58°F (sets to glass)
Vapor pressure: 0.05 mmHg
Flash point: 209°F
Specific gravity: 0.923

Lower explosive limit (LEL): 1.3% (calc)
Upper explosive limit (UEL): 8.1% (calc)
NFPA health rating: 2
NFPA fire rating: 1
NFPA reactivity rating: 0
Appearance: colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92400 @ 25.00 °C.
Melting Point: -40.00 °C. @ 760.00 mm Hg
Boiling Point: 197.00 to 199.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.096000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.1 ( Air = 1 )
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 0.004 (est)
Soluble in: alcohol
water, 3.256e+004 mg/L @ 25 °C (est)
water, 1.00E+06 mg/L @ 25 °C (exp)



FIRST AID MEASURES of HEXASOL HEXYLENE GLYCOL:
-Description of first-aid measures:
*General advice
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXASOL HEXYLENE GLYCOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXASOL HEXYLENE GLYCOL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXASOL HEXYLENE GLYCOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 240 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXASOL HEXYLENE GLYCOL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Store under inert gas.
Hygroscopic.



STABILITY and REACTIVITY of HEXASOL HEXYLENE GLYCOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


HEXYL CELLOSOLVE SOLVENT
A high boiling point, slow evaporating solvent with excellent solvency characteristics.
Hexyl CELLOSOLVE Solvent has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.
As a result, Hexyl CELLOSOLVE Solvent provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.

CAS: 112-25-4
MF: C8H18O2
MW: 146.23
EINECS: 203-951-1

The linear hexyl portion of this provides excellent oil solubility characteristics that make Hexyl CELLOSOLVE Solvent useful in both consumer and industrial cleaner applications.
Hexyl CELLOSOLVE Solvent plays an important role in specialty printing inks.
Because of Hexyl CELLOSOLVE Solvent's limited water solubility and slow evaporation, it can be used in formulations for the silk screen process to prevent premature setting of the ink.
Hexyl CELLOSOLVE Solvent is a high boiling point, slow evaporating rate solvent with excellent solvency characteristics.
Hexyl CELLOSOLVE Solvent has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.

As a result, Hexyl CELLOSOLVE Solvent provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.
Hexyl CELLOSOLVE Solvent used as solvent in specialty printing inks, coalescent for water-borne latex-based coatings, primary solvent in solvent-based silk screen printing inks.
Possesses high boiling point.
Exhibits very good solvency, superior oil solubility, and slow evaporation rate.
Hexyl CELLOSOLVE Solvent is a glycol ether that has a chemical formula of C8H18O2.

Hexyl CELLOSOLVE Solvent Chemical Properties
Melting point: -45.1℃
Boiling point: 98-99°C 0,15mm
Density: 0.888 g/mL at 20 °C(lit.)
Vapor pressure: 10Pa at 20℃
Refractive index: n20/D 1.431
Fp: 98-99°C/0.15mm
Storage temp.: -15°C
pka: 14.44±0.10(Predicted)
Form: clear liquid
Color: Colorless to Light yellow
Water Solubility: Soluble in alcohol and ether, water (9.46 g/L ).
BRN: 1734691
LogP: 1.97 at 25℃
CAS DataBase Reference: 112-25-4(CAS DataBase Reference)
EPA Substance Registry System: Hexyl CELLOSOLVE Solvent (112-25-4)

Uses
Hexyl CELLOSOLVE Solvent is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Hexyl CELLOSOLVE Solvent is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.
Hexyl CELLOSOLVE Solvent is used as high-boiling solvent.
Hexyl CELLOSOLVE Solvent also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.
Hexyl CELLOSOLVE Solvent serves as a coalescing agent in cleaners and latex paints.

Hexyl CELLOSOLVE Solvent is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.
Hexyl CELLOSOLVE Solvent can be used as solvent in specialty printing inks.
Hexyl CELLOSOLVE Solvent can be used as coalescent for water-borne.
Hexyl CELLOSOLVE Solvent can be used as coupling agent and solvent in household and industrial clearners, rust removers, hard surface cleaners and disinfectants.
Hexyl CELLOSOLVE Solvent can be used as primary solvent in solvent-based silk screen printing inks.

Hazards
According to the European Chemicals Agency, Hexyl CELLOSOLVE Solvent is classified as harmful when in contact with skin and when swallowed.
Hexyl CELLOSOLVE Solvent can also cause skin burns and serious eye damage.
Hexyl CELLOSOLVE Solvent was also known to cause kidney injury and depression.
Hexyl CELLOSOLVE Solvent is also a severe respiratory tract irritant.
Hexyl CELLOSOLVE Solvent may also have blood effects.
Hexyl CELLOSOLVE Solvent may enter the body through ingestion, aerosol inhalation, and through the skin.
Hexyl CELLOSOLVE Solvent may form explosive peroxides.
Hexyl CELLOSOLVE Solvent can react violently with strong oxidants.
Hexyl CELLOSOLVE Solvent is classified as a green circle product EPA Safer Choice meaning it is of low concern.

Synonyms
2-(Hexyloxy)ethanol
112-25-4
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
Ethylene glycol n-hexyl ether
2-Hexyloxy-1-ethanol
Ethanol, 2-hexyloxy-
Ethylene glycol-n-monohexyl ether
HSDB 5569
2-n-(Hexyloxy)ethanol
EINECS 203-951-1
BRN 1734691
UNII-7P0O8282NR
DTXSID1026908
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
EC 203-951-1
31726-34-8
4-01-00-02383 (Beilstein Handbook Reference)
DTXCID606908
2-(hexyloxy)ethan-1-ol
CAS-112-25-4
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
Etanol, 2-(hexiloxi)-
2-(1-Hexyloxy) ethanol
Ethylene glycol hexyl ether
SCHEMBL24741
CHEMBL3188016
(C2-H4-O)mult-C6-H14-O
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-66802
FT-0631642
H0343
EN300-114321
F71224
500-077-5 (NLP #)
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
HEXYL CELLOSOLVE SOLVENT
Hexyl cellosolve solvent is a high boiling point, slow evaporating rate solvent with excellent solvency characteristics.
Hexyl cellosolve solvent has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.
As a result, Hexyl cellosolve solvent provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.

CAS: 112-25-4
MF: C8H18O2
MW: 146.23
EINECS: 203-951-1

Synonyms
2-(hexyloxy)-ethano;N-HEXYLMONOOXYETHYLENE;N-HEXYL CELLOSOLVE;C6E1;ETHYLENE GLYCOL MONOHEXYL ETHER;ETHYLENE GLYCOL MONO-N-HEXYL ETHER;ETHYLENE GLYCOL N-HEXYL ETHER;HEXYLGLYCOL
2-(Hexyloxy)ethanol;Ethanol, 2-(hexyloxy)-, 2-(HEXYLOXY)ETHANOL, 2-(Hexyloxy)ethanol C6E1 Hexylglycol, Hexyl Cellosolve, Ethylene Glycol Monohexyl Ether, 2-(Hexyloxy)ethanol, n-Hexylglycol, Ethylene glycol monohexyl ether, Ethylene glycol n-hexyl ether, 2-(Hexyloxy) ethanol, Ethylenglykolmonohexylether, 2-Hexyloxyethanol, 2-(Hexyloxy)ethanol, HEXYL GLYCOL, 2-Hexyloxyethanol, Hexoxyethylene glycol, 2-hexyloxyethanol, Ethylene glycol monohexyl ether, 2-hexyloxyethanol;112-25-4;Ethylene glycol monohexyl ether;2-Hexyloxyethanol;Ethanol, 2-(hexyloxy)-;2-HEXOXYETHANOL;Hexyl cellosolve;n-Hexyl cellosolve;Glycol monohexyl ether;Cellosolve, N-hexyl-;2-Hexyloxy-1-ethanol;Ethylene glycol n-hexyl ether;DTXSID1026908;7P0O8282NR;Ethylene glycol mono-n-hexyl ether;MFCD00045997;31726-34-8;DTXCID606908;Ethanol, 2-hexyloxy-;2-(hexyloxy)ethan-1-ol;CAS-112-25-4;Ethylene glycol-n-monohexyl ether;HSDB 5569;2-n-(Hexyloxy)ethanol;EINECS 203-951-1;BRN 1734691;Hexylglycol;UNII-7P0O8282NR;2-hexyloxy-ethanol;2-(n-Hexyloxy)ethanol;Ethylenglykolmonohexylether;2-(1-Hexyloxy) ethanol;EC 203-951-1;SCHEMBL24741;4-01-00-02383 (Beilstein Handbook Reference);C6E1;CHEMBL3188016;Tox21_202105;Tox21_300545;AKOS009156771;NCGC00248089-01;NCGC00248089-02;NCGC00254448-01;NCGC00259654-01;LS-13544;FT-0631642;H0343;NS00007590;EN300-114321;F71224;W-109065;Q27268660;Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)

A high boiling point, slow evaporating solvent with excellent solvency characteristics.
Hexyl cellosolve solvent has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.
As a result, Hexyl cellosolve solvent provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.
The linear hexyl portion of this provides excellent oil solubility characteristics that make Hexyl cellosolve solvent useful in both consumer and industrial cleaner applications.
Hexyl cellosolve solvent plays an important role in specialty printing inks.
Because of its limited water solubility and slow evaporation, Hexyl cellosolve solvent can be used in formulations for the silk screen process to prevent premature setting of the ink.
Hexyl cellosolve solventl or 2-(Hexyloxy)ethanol is a glycol ether that has a chemical formula of C8H18O2.

Hexyl cellosolve solvent Chemical Properties
Melting point: -45.1℃
Boiling point: 98-99°C 0,15mm
Density: 0.888 g/mL at 20 °C(lit.)
Vapor pressure: 10Pa at 20℃
Refractive index: n20/D 1.431
Fp: 98-99°C/0.15mm
Storage temp.: -15°C
pka: 14.44±0.10(Predicted)
Form: clear liquid
Color: Colorless to Light yellow
Water Solubility: Soluble in alcohol and ether, water (9.46 g/L ).
BRN: 1734691
LogP: 1.97 at 25℃
CAS DataBase Reference: 112-25-4(CAS DataBase Reference)
EPA Substance Registry System: Hexyl cellosolve solvent (112-25-4)

Uses
Hexyl cellosolve solvent is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Hexyl cellosolve solvent is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.
Hexyl cellosolve solvent is used as high-boiling solvent.
Hexyl cellosolve solvent also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.
Hexyl cellosolve solvent serves as a coalescing agent in cleaners and latex paints.

Hazards
According to the European Chemicals Agency, Hexyl cellosolve solvent is classified as harmful when in contact with skin and when swallowed.
Hexyl cellosolve solvent can also cause skin burns and serious eye damage.
Hexyl cellosolve solvent was also known to cause kidney injury and depression.
Hexyl cellosolve solvent is also a severe respiratory tract irritant.
Hexyl cellosolve solvent may also have blood effects.
Hexyl cellosolve solvent may enter the body through ingestion, aerosol inhalation, and through the skin.
Hexyl cellosolve solvent may form explosive peroxides.
Hexyl cellosolve solvent can react violently with strong oxidants.
Hexyl cellosolve solvent is classified as a green circle product EPA Safer Choice meaning it is of low concern.
HEXYL GLYCOL
HEXYL GLYCOL = n-HEXYL GLYCOL = ETHYLENE GLYCOL MONOHEXYL ETHER = 2-(HEXYLOXY)ETHANOL


CAS number: 112-25-4
EC number: 203-951-1
MDL Number: MFCD00045997
Molecular formula: C8H18O2


Hexyl glycol is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
Hexyl glycol is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.
Hexyl glycol's miscibility with water, however, is limited.
Hexyl glycol enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.


Since Hexyl glycol may react with the oxygen in the air to form peroxides.
Hexyl glycol, as known 2-Hexoxyethanol or 2-(Hexyloxy)ethanol, is a glycol ether that has a chemical formula of C8H18O2.
Hexyl glycol (Ethylene Glycol Monohexyl Ether), n°112-25-4 is measured by GC-FID.
A sample material must be taken using special equipment.


Hexyl glycol (Cas No.: 112-25-4) is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.
Hexyl glycol is a colorless liquid with a slight ether-like odor and bitter taste
Hexyl glycol's vapour is heavier than air.
Hexyl glycol is a colorless liquid with a slight ether odor and bitter taste.



USES and APPLICATIONS of HEXYL GLYCOL:
Hexyl glycol is used Industry, Scientific Research, Health, Environmental Protection, Agriculture
Usage of Hexyl glycol: Laboratory Reagents, Analytical Reagents, Diagnostic Reagents, Teaching Reagents
Hexyl glycol is mainly used as a solvent, flow promoter and coalescent aid in the coatings industry and in printing inks and cleaners.
Hexyl glycol is used Clear, mobile, high-boiling, low-volatility liquid for use as a solvent, flow promoter and coalescent.
By virtue of its good solvent power, the main applications of n-Hexylglycol are as a solvent, flow promoter and coalescent aid.


For instance, it improves the flow of many baking finish systems.
Added in small proportions to formulations for electrodeposition paints, it greatly improves film formation and levelling.
Hexyl glycol is also eminently suitable as a mild, low-odour co-solvent in low-aromatic mineral spirit blends for dissolving polymer binders such as Acronal 260 F.
Hexyl glycol can also be used in printing inks and cleaners.


Hexyl glycol is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Other uses of Hexyl glycol are: Sealants, Adhesives, Coating products, Finger Paints, Fillers, Anti-freeze products, Plasters, Putties, Lubricants, Modelling Clay, Greases, Automotive care products, Machine wash liquids/detergents, Air fresheners, Fragrances, and Other outdoor use.
Hexyl glycol is used as a high-boiling solvent.


Hexyl glycol is used as a chemical intermediate for hexyloxyethyl phosphate and neopentanoate.
Hexyl glycol is used as a coalescing agent in latex paints and cleaners.
Hexyl glycol is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.
Hexyl glycol is used as high-boiling solvent.


Hexyl glycol also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.
Hexyl glycol serves as a coalescing agent in cleaners and latex paints.
Hexyl glycol is mainly used as solvents for cleaning fluids, paints, coatings and ink preparations.
Hexyl glycol has excellent oil solubility, making it effective in household and industrial cleaning applications.


Hexyl glycol is used as a coalescing agent for water-based latex-based coatings and plays an important role in specialty printing inks, including screen printing processes, where its limited water solubility and slow evaporation rate prevent premature ink settling .
Two solvents, Hexyl glycol and diethylene glycol hexyl ether, are potential replacements for halogenated hydrocarbons in non-vapor degreasing applications.
Hexyl glycol is used as high-boiling solvent, Solvents (which become part of product formulation or mixture), and Cleaning and furnishing care products


Hexyl glycol can be used as coalescent for water-borne.
Hexyl glycolcan be used as coupling agent and solvent in household and industrial clearners, rust removers, hard surface cleaners and disinfectants.
Hexyl glycol can be used as primary solvent in solvent-based silk screen printing inks.
Hexyl glycol is used for Biological Purpose, For Microscopic Purpose, For Lens Blooming, Technical Grade, Pratical Use, Pro Analysis, Super Special Grade, For Synthesis, For Electrophoresis Use.


Hexyl glycol can be used as a solvent in lacquers, paints, resins, dyes, oils and lubricants, as well as as a coupling and dispersant.
Hexyl glycol can be used as a solvent for paints, paints, resins, dyes, oils and lubricating oils, as well as coupling and dispersing agents.
Hexyl glycol is used as special solvent for coating and ink.
Hexyl glycol can be used as solvent in specialty printing inks.



ALTERNATIVE PARENTS of HEXYL GLYCOL:
*Primary alcohols
*Hydrocarbon derivatives



SUBSTITUENTS of HEXYL GLYCOL:
*Dialkyl ether
*Hydrocarbon derivative
*Primary alcohol
*Alcohol
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of HEXYL GLYCOL:
Molar mass 146.23 g/mol
n-Hexylglycol: 98.0 min. %
Water: 0.1 max. %
Pt/Co color value (Hazen): 10 max.
Acid value: 0.1 max mg KOH/g
Boiling range at 1013 hPa; 95 Vol.-%; 2 – 97 ml 200 – 212 °C
Density at 20 °C: 0.887 – 0.890 g/cm3
Refractive index: nD20 1.428 – 1.430
Solidification point: at 1013 hPa - 42 °C (ice flakes)
Evaporation rate ether: 1 approx. 1200
Enthalpy of combustion: at 25 °C 33 136 kJ/kg -
Enthalpy of vaporization: at 25 °C 475 kJ/kg -
Enthalpy of vaporization: at boiling point 325 kJ/kg
Enthalpy of formation: at 25 °C - 3 776 kJ/kg -

Dipole moment: (µ) 2.08 D
Solubility Mass fraction of Hexyl glycol in water: 1.0 %
Water in Hexyl glycol: 18.8 %
Water Solubility: 4.22 g/L
logP: 1.82
logP: 1.65
logS: -1.5
pKa (Strongest Acidic): 15.12
pKa (Strongest Basic): -2.7
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 1
Polar Surface Area: 29.46 Ų
Rotatable Bond Count: 7

Refractivity: 42.38 m³·mol⁻¹
Polarizability: 18.54 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes
S.G @ 20C/20C: 0.887
Distillation Range C Min: 200
Distillation Range C Max: 212
Evaporation Rate Ether = 1: >1200
Flash Point Deg C: 92
Solubility % wt in Water: @ 20C 1

Appearance and properties: transparent liquid
Density: 0.888 g/mL at 20 °C(lit.)
Boiling point: 98-99°C 0,15mm
Melting point: -45.1ºC
Flash point: 98-99°C/0.15mm
Refractive index: n20/D 1.431
Appearance: Colorless Clear Liquid
Content, GC%Wt: ≥98.0
Acidity,%Wt.(calculated as acetic acid): ≤0.01
Moisture,%Wt: ≤0.15
Chroma, Hazen unit (platinum-cobalt color number): ≤15
Min. Purity Spec: >99% (GC)
Physical Form (at 20°C): Liquid
Melting Point: -42°C

Boiling Point: 208°C
Flash Point: 94°C
Density: 0.89
Refractive Index: 1.43
Long-Term Storage: Store long-term in a cool, dry place
Appearance Form: liquid
Color: colorless
Odor: ether-like
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: -50,1 °C at 1.013 hPa
Initial boiling point and boiling range: 208,5 °C at 1.013 hPa

Flash point: 90 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 0,1 hPa at 22,9 °C - OECD Test Guideline 104
Vapor density: No data available
Density: 0,888 g/mL at 20 °C
Relative density: No data available
Water solubility: 9,46 g/l - soluble
Partition coefficient: n-octanol/water:
log Pow: 1,97 at 25 °C
Autoignition temperature: 225 °C at 1.008 - 1.015 hPa
Decomposition temperature: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 4,4 mPa.s at 20 °C
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Appearance (20°)C : Clear Liquid
Color (APHA or less) : 15
Specific gravity (20°C) : 0.887~0.892
Acidity (% or less) : 0.01
Water content (% or less) : 0.2
Purity (% or more) : 98
Molecular Weight: 146.23
XLogP3: 1.9

Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 7
Exact Mass: 146.130679813
Monoisotopic Mass: 146.130679813
Topological Polar Surface Area: 29.5 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 55.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of HEXYL GLYCOL:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing: make victim drink water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXYL GLYCOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of HEXYL GLYCOL:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXYL GLYCOL:
-Control parameters
--Ingredients with workplace control parameters
-Exposure controls
--Personal protective equipment
*Eye/face protection
Use equipment for eye protection.
Tightly fitting safety goggles.
*Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Wash and dry hands.
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXYL GLYCOL:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store under inert gas.



STABILITY and REACTIVITY of HEXYL GLYCOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
C6E1
2-(Hexyloxy)ethanol
Hexylglycol
2-(HEXYLOXY)ETHANOL
2-N-(HEXYLOXY)ETHANOL
C6E1
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
ETHYLENE GLYCOL N-HEXYL ETHER
HEXYLGLYCOL
N-HEXYL CELLOSOLVE
N-HEXYLMONOOXYETHYLENE
2-(hexyloxy)-ethano
2-Hexoxyethanol
2-hexyloxy-ethano
Cellosolve, n-hexyl-
ethyleneglycol-n-monohexylether
Glycol monohexyl ether
glycolmonohexylether
Hexyl cellosolve
hexylcellosolve
n-hexyl-cellosolv
Ethylenegylcolmono-N-hexylether
2-(Hexyloxy)ethanol
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
2-Hexyloxy-1-ethanol
Ethylene glycol n-hexyl ether
2-n-(Hexyloxy)ethanol
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DSSTox_CID_6908
DSSTox_RID_78248
DSSTox_GSID_26908
31726-34-8
Ethanol, 2-hexyloxy-
Ethylene glycol-n-monohexyl ether
HSDB 5569
Hexyl alcohol, ethoxylated
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
Ethylene glycol hexyl ether
SCHEMBL24741
4-01-00-02383
CHEMBL3188016
DTXSID1026908
Poly(oxy-1,2-ethanediyl), .alpha.-hexyl-.omega.-hydroxy-
ZINC2041054
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
DB-041064
FT-0631642
H0343
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
Hexyl laurate
hexyl laurate; Hexyl dodecanoate; Dodecanoic acid, hexyl ester; Hexyllaurat;Lauric acid hexyl ester; Einecs 251-932-1; Hexyl dodecanoat; Laurinsaeurehexylester cas no: 34316-64-8
HEXYLDECANOL
HEXYLDECANOL, N° CAS : 2425-77-6 - Hexyldécanol, Nom INCI : HEXYLDECANOL, Nom chimique : 2-Hexyldecan-1-ol, N° EINECS/ELINCS : 219-370-1, Compatible Bio (Référentiel COSMOS), Ses fonctions (INCI), Emollient : Adoucit et assouplit la peau, Agent d'entretien de la peau : Maintient la peau en bon état
HEXYLDECYL LAURATE
Hexyldecyl stearate; Octadecanoic acid, 2-hexyldecyl ester; 17618-45-0; Eutanol G 16S; 2-Hexyldecyl stearate cas no: 17618-45-0
HEXYLDECYL STEARATE
HEXYLENE GLYCOL; 2-Methyl-2,4-pentanediol; Diolane; Hexylene glycol; 2-Methylpentane-2,4-diol; 2-Metilpentano-2,4-diol; 2-Méthylpentane-2,4-diol; (+-)-2-Methyl-2,4-pentanediol; 1,1,3-Trimethyltrimethylenediol; 2,4-Dihydroxy-2-methylpentane; 4-Methyl-2,4-pentanediol; alpha,alpha,alpha'-Trimethyltrimethylene glycol; cas no: 107-41-5, 99113-75-4
HEXYLDECYL STEARATE
Hexyldecyl stearate is a versatile emollient and solvent widely used in personal care products like skin creams, lotions, and sunscreens due to its ability to soften skin and reduce oiliness.
As a clear, low-viscosity ester, Hexyldecyl stearate enhances the spreadability and smoothness of formulations, making it ideal for cosmetics such as lipsticks, eye makeup, and skin care products.
In addition to its cosmetic applications, Hexyldecyl stearate is utilized as a lubricant and processing agent in industries like metalworking, textiles, and plastics, thanks to its excellent thermal stability and hydrophobic properties.

CAS Number: 22047-49-0
EC Number: 244-754-0
Molecular Formula: C26H52O2
Molecular Weight: 396.6899

Synonyms: 22047-49-0 [RN], 244-754-0 [EINECS], 2-ethylhexyl octadecanoate, 2-Ethylhexyl stearate [ACD/IUPAC Name], 2-Ethylhexylstearat [German] [ACD/IUPAC Name], ETHYLHEXYL STEARATE, Octadecanoic acid, 2-ethylhexyl ester [ACD/Index Name], Stéarate de 2-éthylhexyle [French] [ACD/IUPAC Name], [22047-49-0], 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3), 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3), Technical grade, 2-Ethylhexyloctadecanoate, 2-ETHYLHEXYLSTEARATE, AGN-PC-00L26C, CHEMBL3184927, DSSToxCID27178, DSSToxGSID47178, DSSToxRID82175, ethyl 4-hydroxycyclohexane-1-carboxylate, MFCD00072275 [MDL number], SCHEMBL153398, stearic acid, 2-ethylhexyl ester, Octadecanoic acid, octyl ester [ACD/Index Name], octyl octadecanoate, Octyl stearate [ACD/IUPAC Name], Octylstearat [German] [ACD/IUPAC Name], Stéarate d'octyle [French] [ACD/IUPAC Name], Stearic acid, octyl ester, 22047-49-0 [RN], 244-754-0 [EINECS], 2-ethylhexyl octadecanoate, 2-Ethylhexyl stearate [ACD/IUPAC Name], 2-Ethylhexylstearat [German] [ACD/IUPAC Name], ETHYLHEXYL STEARATE, Octadecanoic acid, 2-ethylhexyl ester [ACD/Index Name], Stéarate de 2-éthylhexyle [French] [ACD/IUPAC Name], [22047-49-0] [RN], 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3), 2-Ethylhexyloctadecanoate, 2-ETHYLHEXYLSTEARATE, AGN-PC-00L26C, CHEMBL3184927, DSSToxCID27178, DSSToxGSID47178, DSSToxRID82175, ethyl 4-hydroxycyclohexane-1-carboxylate, MFCD00072275 [MDL number], SCHEMBL153398, stearic acid, 2-ethylhexyl ester, 2-Ethylhexyl stearate, 22047-49-0, 2-Ethylhexyl octadecanoate, Ethylhexyl stearate, Cetiol 868, Octadecanoic acid, 2-ethylhexyl ester, EG3PA2K3K5, DTXSID9047178, Stearic acid, 2-ethylhexyl ester, C26H52O2, ethyl hexyl stearate, CRODAMOL OS, TEGOSOFT OS, ETHOX EHS, PELEMOL OS, EXCEPARL EH-S, UNII-EG3PA2K3K5, SCHEMBL153398, ?2-ETHYLHEXYL STEARATE, ESTOL 1545, CHEMBL3184927, DTXCID7027178, OPJWPPVYCOPDCM-UHFFFAOYSA-N, ETHYLHEXYL STEARATE [INCI], Tox21_302619, ETHYLHEXYL STEARATE [WHO-DD], MFCD00072275, AKOS015901877, NCGC00256861-01, CAS-22047-49-0, CS-0152204, FT-0756635, E78095, EC 244-754-0, W-110539, Q27277167, OCTADECANOIC ACID, 2-ETHYLHEXYL ESTER, (+/-)-, 2-Ethylhexyl stearate, mixture of stearate and palmitate (4:6)

Hexyldecyl stearate is commonly used as an emollient to deliver skin-softening properties and a smooth afterfeel.
Hexyldecyl stearate is a medium spreading emollient for all kind of cosmetic applications.

Hexyldecyl stearate or 2-Ethylhexyl stearate is an ester of stearic acid with octanol.
Hexyldecyl stearate is again one member of the groups called stearate esters which are obtained by reacting stearic acid with an alkyl group containing alcohol.

Stearate esters all have unique properties of oily nature, but low viscosity and lighter feel.
That’s why they are the choice of solvents in makeup related products.

Hexyldecyl stearate is obtained from various animal and plant source.
Hexyldecyl stearate comes as clear to slightly yellowish liquid.

Hexyldecyl stearate, also known as Ethylhexyl Stearate or 2-Ethylhexyl stearate, is a renewable palm derivative with a variety of uses in both personal care and cosmetics manufacturing.
Hexyldecyl stearate is a stearate ester with similar properties to Isopropyl Myristate.
As with all stearate personal care esters, the Hexyldecyl stearate manufacturing process entails a reaction between Hexyldecyl stearate and alcohols such as cetyl, butyl, isopropyl or myristyl alcohol.

Hexyldecyl stearate is a fatty acid derived from animal fat.
Hexyldecyl stearate acts as a lubricant that softens the skin and gives Hexyldecyl stearate a smooth appearance.

Hexyldecyl stearate is excellent liquid emollient and thickening agent for cosmetic formulations.
Hexyldecyl stearate provides a soft barrier to the skin to impart moisturization and a smooth feel.

Hexyldecyl stearate is a clear, almost colorless (or slightly yellowish) oily liquid (an ester to be precise) that's used as a medium spreading emollient.
Hexyldecyl stearate gives skin a nice and smooth after-feel and it's very good at reducing oiliness or greasiness coming from other heavier oils in the formula.

Hexyldecyl stearate is used an emollient derived from plant oil that prevents water loss
Hexyldecyl stearate is also known as 2-Ethylhexyl stearate.

Hexyldecyl stearate also known as 2-Ethylhexyl Octadecanoate or 2-Ethylhexyl stearate is a palm derivative which is renewable in nature and is extensively used in personal care industry.
The stearate esters are prepared by the reaction between Hexyldecyl stearate and alcohol such as isopropyl, ethylhexyl, myistyl alcohol, cetyl, butyl among others.

Hexyldecyl stearate can be obtained form from animal origin as well as vegetable fats.
Hexyldecyl stearate is prepared by the reaction between Hexyldecyl stearate and ethylhexyl alcohol.

Hexyldecyl stearate is a clear ester liquid which is free of suspended matter and is available in colourless liquid form.
Ethylhexyl alcohol possess unique property of low viscosity and oily nature owing to which when applied on skin or lips Hexyldecyl stearate forms an hydrophobic film.
Thereby, softens the skin and imparts smooth appearance.

With rising consumer concern towards personal health, demand for personal care serices and products are witnessing a substantial growth.
Thereby, boosting the market growth of Hexyldecyl stearate as Hexyldecyl stearate is commonly used ester in personal care products.

Hexyldecyl stearate is commonly used as an emollient which prevents the water loss.
Hence, is extensively used as emulsion, bath oils and as solvent in cosmetic products.

Hexyldecyl stearate is widely used in the manufacturing of formulations for skin make up, lipstick, eye liner and other skin care products.
Apart from personal care industry, Hexyldecyl stearate also widely used as an intermediate, lubricating agent and surface active agent.

Owing to these properties ethtylhexyl stearate is commonly used in the manufacturing of metal working fluids.
Also, Hexyldecyl stearate offers good thermal stability and hence finds application in aluminium rolling, also is used in manufacturing of ink additives and paints.
Hence, broad spectrum of application provides an opportunistic platform for the robust growth of Hexyldecyl stearate market over the period of time.

Hexyldecyl stearate is a special emollient ester in cosmetic formulations.
Hexyldecyl stearate is a softening, thickening agent, dispersant and solvent.

Hexyldecyl stearate is often used as a base for skin care agents.
Hexyldecyl stearate is suitable for use in lotions, sunscreens, hair care, lip care, eye care, antiperspirant and bath oils.
Hexyldecyl stearate is oil soluble and supplied as a whitish clear liquid.

Hexyldecyl stearate, also known as Ethylhexyl Stearate or 2-Ethylhexyl stearate, is a renewable palm derivative that has a variety of uses in both personal care and cosmetic manufacturing.
Hexyldecyl stearate is a stearate ester with similar properties to Isopropyl Myristat.

As with all stearate personal care esters, the Hexyldecyl stearate manufacturing process causes a reaction between Hexyldecyl stearate and alcohols such as cetyl, butyl, isopropyl or myristyl alcohol.
Hexyldecyl stearate acts as a lubricant that softens the skin and gives Hexyldecyl stearate a smooth appearance.

Hexyldecyl stearate or 2-Ethylhexyl stearate, is a date derivative that is renewable in nature and widely used in the personal care industry.
Stearate esters are prepared by the reaction between Hexyldecyl stearate and alcohol such as isopropyl, ethylhexyl, myistyl alcohol, cetyl, butyl, among others.

Hexyldecyl stearate can be obtained from vegetable oils as well as from animal origin.
Hexyldecyl stearate is prepared by the reaction between Hexyldecyl stearate and ethylhexyl alcohol.

Hexyldecyl stearate is a clear ester liquid with no suspended matter and available in colorless liquid form.
Ethylhexyl alcohol has a unique property of low viscosity and oily nature, as Hexyldecyl stearate forms a hydrophobic film when applied to the skin or lips.
Thus, Hexyldecyl stearate softens the skin and gives Hexyldecyl stearate a smooth appearance.

Hexyldecyl stearate is an excellent moisturizer with low comedogenicity and medium spreading properties.
Hexyldecyl stearate gives the skin a soft and smooth appearance while preventing water loss.
Hexyldecyl stearate is very suitable for use in sun screen formulations.

Hexyldecyl stearate is a renewable palm derivative with a variety of uses in both personal care and industrial applications.
Hexyldecyl stearate is used in cosmetic formulations as a solvent, carrying agent, wetting agent, emollient, and used mostly in the formulation of, eye/skin makeup, lipstick and skin care products.
Hexyldecyl stearate also widely used in metal working fluids, textile auxiliaries and lube & grease.

Hexyldecyl stearate is a chemical compound that belongs to the family of esters.
Hexyldecyl stearate is commonly used in various industries, including cosmetics, pharmaceuticals, and plastics.
This paper aims to provide a comprehensive review of Hexyldecyl stearate, including Hexyldecyl stearate method of synthesis or extraction, chemical structure, biological activity, biological effects, applications, future perspectives, and challenges.

Hexyldecyl stearate is a low odor product with resistance to extraction by water, oils and solvents.
Hexyldecyl stearate is the least effective costabilizer on Hexyldecyl stearate range due to Hexyldecyl stearate lower oxirane value but is good at reducing viscosity in plastisols and remains liquid down to -20°C.

Hexyldecyl stearate is used in cosmetics to provide a barrier between skin and the elements, and to soften and smooth the skin.
Hexyldecyl stearate used in cosmetics as a thickening agent and emollient.

Hexyldecyl stearate used as plasticizer for natural rubber and synthetic rubber.
Hexyldecyl stearate used as release agent.

Hexyldecyl stearate used as lubricating agent for process aluminium foil; creates plasticity.
Hexyldecyl stearate used in the pharmaceutical industry and in plastics; oil agent of textile; additive for leather.

Hexyldecyl stearate is a light ester with low viscosity (7-10,5 cSt) and emollient properties.
Hexyldecyl stearate improves the spreadability of preparations, Hexyldecyl stearate easily absorbed and leaves a non-greasy, non-occlusive protective film on the skin, which feels silky and smooth.
Hexyldecyl stearate is ideal on makeup formulations such as lipsticks and mascaras.

Hexyldecyl stearate is an ester of stearic acid and 2-ethylhexanol.
Hexyldecyl stearate is a clear, colorless liquid with a faint odor and a low viscosity.

The chemical formula of Hexyldecyl stearate is C26H52O2, and Hexyldecyl stearate has a molecular weight of 368.64 g/mol.
Hexyldecyl stearate is commonly used in the cosmetic industry as an emollient and a solvent.

As an emollient, Hexyldecyl stearate has a softening and smoothing effect on the skin and hair, making them feel less greasy and more comfortable.
As a solvent, Hexyldecyl stearate can dissolve other ingredients and help them spread more evenly on the skin or hair.
Hexyldecyl stearate is considered safe for use in cosmetics, and Hexyldecyl stearate low toxicity makes Hexyldecyl stearate an attractive ingredient for a variety of personal care products.

Hexyldecyl stearate is also known as 2-Ethylhexyl stearate, Hexyldecyl stearate can be used as a lubricant in all kinds of cosmetic products.
Hexyldecyl stearate is an IPM alternative.
Hexyldecyl stearate has a medium-low lubrication feel.

Hexyldecyl stearate can be used in products where oiliness is not desired.
Hexyldecyl stearate will also reduce the oiliness of other oils.

Hexyldecyl stearate is a cream-type cleansing cosmetic compound containing large amount of oil phase and Hexyldecyl stearate manufacturing method.
In cosmetics and personal care products, stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products.

Hexyldecyl stearate is used in personal care applications and and in can lubes.
Hexyldecyl stearate is a palm dervied product made from Stearic Acid and 2-Ethylhexanol.

Hexyldecyl stearate can be considered a protector of the skin.
Hexyldecyl stearate is an emollient derived from plant oil.

The lipide prevents water loss and therefore helps the skin to efficiently store moisture.
Hexyldecyl stearate is acts as a good moisturizer and emollient for skin creams, lotions and sunscreen.

Hexyldecyl stearate is a cationic polymerization that is used in the production of polyvinyl chloride.
Hexyldecyl stearate has been shown to be an effective additive for hydrophobic effects, and Hexyldecyl stearate has very high values for surface methodology.

Hexyldecyl stearate is also clinically proven to have skin cell penetration properties and can be used as a carrier agent for other ingredients.
The fatty acid portion of this molecule provides hydroxyl groups, which may help with the function of dimethyl fumarate.
Hexyldecyl stearate also contains a potassium hexafluorophosphate group in Hexyldecyl stearate structure, which can be used as an emulsifier or dispersant.

Hexyldecyl stearate is mainly a skin conditioning ingredient and Hexyldecyl stearate acts primarily as lubricant on the skin's surface, which gives the skin a soft and smooth appearance.
In our products, Hexyldecyl stearate is used as hair conditioner.
Hexyldecyl stearate helps to increase the softness and smoothness of hair, reduce tangles and surface roughness.

Use and Benefits of Hexyldecyl Stearate:
Hexyldecyl stearate is also linked to skin’s natural fatty acid content, so Hexyldecyl stearate is ideal for skin preparation.
Moreover, Hexyldecyl stearate imparts the right amount of viscosity to Hexyldecyl stearate, Hexyldecyl stearate acts as a thickening agent as well.

Hexyldecyl stearate also forms a film over the skin, a hydrophobic barrier which does not let the moisture pass through and escape from the skin.
And without any greasy feel, Hexyldecyl stearate moisturizes the skin.

Hexyldecyl stearate also nourishes the skin and provides a protective barrier; moist skin is healthy enough to fight any external inflammation.
After regular application, resultant skin may become softer and smoother.
Hexyldecyl stearate is most frequently used in skincare products, lipstick, skin makeup, and eye makeup.

Hexyldecyl stearate is a surfactant with a wide variety of applications and can be found, for example, as a solvent in lubricants and lubricant additives, surface treatment agents.
The following consumer products may contain Hexyldecyl stearate: fabrics, textiles and leather products, detergents, dishwashing liquids, lubricants, oils (excluding food oils) and others.

Hexyldecyl stearate is often used as an emollient to prevent water loss.
For this reason, Hexyldecyl stearate is widely used as a solvent in emulsions, bath oils and cosmetic products.

Hexyldecyl stearate is widely used in the production of formulations for skin make-up, lipstick, eyeliner and other skin care products.
Besides the personal care industry, Hexyldecyl stearate is also used as an intermediate, lubricant and surfactant oris widely used.

Because of these properties, Hexyldecyl stearate is widely used in the production of metalworking fluids.
Hexyldecyl stearate also offers good thermal stability and therefore finds application in aluminum rolling, Hexyldecyl stearate is also used in the manufacture of ink additives and paints.
Therefore, Hexyldecyl stearate wide range of applications provides an opportunistic platform for the Hexyldecyl stearate market to grow strongly over time.

However, with the increasing demand for organic and natural personal care products, various natural-based ingredients are used in the production of personal care products.
Thus, Hexyldecyl stearate limits the market growth of Hexyldecyl stearate.

Moreover, Hexyldecyl stearate is derived from animal fat, which is hindering the growth of the Hexyldecyl stearate market with the increasing adoption of vegan-based products.
Hexyldecyl stearate also causes mild eye irritation and produces a mild odor, which may affect the adoption of ethyl stearate-based products among consumers.

Usage Areas:
Hexyldecyl stearate is used in cosmetic Softener, Dispersant, Solvent and Thickener.
Hexyldecyl stearate is used in metalworking lubricant.

Hexyldecyl stearate is branched chain softener ester specially developed for personal care and pharmaceutical applications.
Hexyldecyl stearate is non-occlusive with good spreading properties.

Hexyldecyl stearate is excellent super lubricant in detergent systems and soaps.
Hexyldecyl stearate is increases hair shine.
Hexyldecyl stearate is used in bath oils, skin cleansers, shampoos and conditioners.

Cosmetic use:
Hexyldecyl stearate is used in oil-based with low viscosity, high penetration and spreading effect.

Uses at industrial sites:
Hexyldecyl stearate is used in the following products: washing & cleaning products, metal surface treatment products, polymers, textile treatment products and dyes and pH regulators and water treatment products.
Hexyldecyl stearate is used for the manufacture of: textile, leather or fur.
Release to the environment of Hexyldecyl stearate can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as processing aid and as an intermediate step in further manufacturing of another substance (use of intermediates).

Industry Uses:
Lubricants and lubricant additives
Plating agents and surface treating agents
Solvents (which become part of product formulation or mixture)
Surface active agents
Emulsifier
Hydraulic fluids
Intermediate
Lubricants and lubricant additives
Lubricating agent
Other
Solubility enhancer
Surface modifier
Surfactant (surface active agent)

Consumer Uses:
Hexyldecyl stearate is used in the following products: washing & cleaning products, adhesives and sealants, lubricants and greases, polymers, textile treatment products and dyes, plant protection products, polishes and waxes and fertilisers.
Release to the environment of Hexyldecyl stearate can occur from industrial use: in the production of articles and in processing aids at industrial sites.
Other release to the environment of Hexyldecyl stearate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Other consumer Uses:
Fabric, textile, and leather products not covered elsewhere
Laundry and dishwashing products
Lubricants and greases
Non-TSCA use
Personal care products
Emulsifier
Hydraulic fluids
Intermediate
Lubricants and lubricant additives
Lubricating agent
Other
Solubility enhancer
Surfactant (surface active agent)

Applications of Hexyldecyl Stearate:
Hexyldecyl stearate acts as a good moisturizer and emollient in personal care formulations like skin creams, lotions and sunscreens.
Hexyldecyl stearate is also finds use in color cosmetics like eyebrow pencil, concealer, lipstick etc.
Hexyldecyl stearate is used as an oil component for bath oils, bath emulsions, and as a solvent for active substances in cosmetics.

Hexyldecyl stearate is a variety of resin processing of the lubricant, non-toxic, with water resistance and good thermal stability.
Mainly used for PVC transparent soft and hard extrusion, injection molding, calendering products, the amount of 0.5-1 copies.

Hexyldecyl stearate of the modified vinyl chloride - vinyl acetate copolymer, polystyrene, nitrile rubber and other processing performance is also very effective.
Hexyldecyl stearate can also be used as a lubricant for fabrics, waterproofing agents, lubricants additives, cosmetics base material and so on.

Hexyldecyl stearate is a specialty emollient ester.
Hexyldecyl stearate is a superior emollient, thickening agent, dispersant, and solvent.

Hexyldecyl stearate properties allow use as a cleaner or diluent for lipophilic systems; cosmetic emollient and dispersant; plastic additive as external lubricant; industrial lubricant or separator; substitution of mineral, vegetable and selected silicone oils; and pigment binding and dispersing coagent.

Categories: Thickeners / Emulsifiers, Texture Enhancer, Softeners
Hexyldecyl stearate is often used as an emollient for Hexyldecyl stearate skin softening properties and smooth feel.

Hexyldecyl stearate is often used as the base for skin conditioning agents.
Suitable for use in lotions, sunscreens, hair care, lip care, eye care, antiperspirants, and bath oils.

Hexyldecyl stearates serve as intermediates, surface active agents and lubricants/lubricant additives.

Hexyldecyl stearate is functions include the following.
CASE: Paint and Ink Additive
Lube and Grease: Oil Base Fluid
Metal Working Fluids: Lubricant with Excellent Adhesion to Metals and Good Thermal Stability. Also Used in Aluminum Rolling
Plastics: Lubricant
Rubber: Processing Agent
Textiles: Oiling Agent
Personal Care: Thickening Agent, Skin Conditioning Agent and Emollient in Skin Care Products
Cosmetics: Used as a Base, a Thickening Agent, a Pigment Wetting Agent, a Dispersant, a Solvent and an Emollient in Skin and Eye Make-Up and in Lipstick.
Personal care products/cosmetics using Hexyldecyl stearate: Lipstick, eye makeup, skin care and makeup products, moisturizers, anti-wrinkle creams and lotions, anti-aging products, hair conditioners and styling products, baby lotions and eye shadow

Industry Based Hexyldecyl stearate Applications:
Personal care
Textile
Chemicals

Applications of Hexyldecyl stearate based on functionality:
Lubrication
Processing
Darkening
Distributor

Other Applications:
After sun
Baby Care and Cleaning
Body care
Color Care
Facial Facial
Personal Cleaner
Care Wipes
Self Tanning
Sun protection
Bath, Shower & Soaps
Eye Colour
Face / Neck Skin Care
Face Colour
Facial Cleansers
Hair Conditioners - Rinse off
Lip Colour
Shampoos
Sun Protection
Tanning

Method of Synthesis or Extraction of Hexyldecyl Stearate:
Hexyldecyl stearate can be synthesized by the esterification of stearic acid with 2-ethylhexanol.
The reaction is catalyzed by an acid catalyst, such as sulfuric acid or p-toluenesulfonic acid.

The efficiency and yield of this method depend on the reaction conditions, such as temperature, pressure, and reaction time.
The yield of this method is typically high, ranging from 80% to 95%.
However, this method may have environmental and safety considerations, such as the use of hazardous chemicals and the generation of waste.

Chemical Structure and Biological Activity of Hexyldecyl Stearate:
Hexyldecyl stearate has a chemical formula of C24H48O2 and a molecular weight of 368.64 g/mol.
Hexyldecyl stearate is a colorless to pale yellow liquid with a faint odor.

Hexyldecyl stearate has been shown to have various biological activities, including anti-inflammatory, antioxidant, and antimicrobial activities.
Hexyldecyl stearate acts by inhibiting the production of pro-inflammatory cytokines, scavenging free radicals, and disrupting the cell membrane of microorganisms.

Biological Effects of Hexyldecyl Stearate:
Hexyldecyl stearate has been shown to have potential therapeutic effects on various diseases, such as acne, psoriasis, and atopic dermatitis.
Hexyldecyl stearate can improve skin hydration, reduce skin irritation, and enhance the penetration of active ingredients.

However, Hexyldecyl stearate may also have potential toxic effects, such as skin sensitization, eye irritation, and reproductive toxicity.
The toxicity of Hexyldecyl stearate depends on the dose, exposure route, and duration.

General Manufacturing Information of Hexyldecyl Stearate:

Industry Processing Sectors:
All Other Chemical Product and Preparation Manufacturing
Computer and Electronic Product Manufacturing
Electrical Equipment, Appliance, and Component Manufacturing
Fabricated Metal Product Manufacturing
Machinery Manufacturing
Miscellaneous Manufacturing
Oil and Gas Drilling, Extraction, and Support activities
Petroleum Lubricating Oil and Grease Manufacturing
Printing Ink Manufacturing
Printing and Related Support Activities
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
Textiles, apparel, and leather manufacturing
Transportation Equipment Manufacturing

Functions of Hexyldecyl Stearate:
According to Chemiplast, a Belgian researcher, Hexyldecyl stearate is used as an oil component for emulsions, bath oils, and as a solvent for active substances in cosmetics.
Stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products.

Properties of Hexyldecyl Stearate:
Hexyldecyl stearate is a clear liquid ester that is free of suspended matter, although Hexyldecyl stearate may also be a waxy solid.
Colorless in its liquid form, Hexyldecyl stearate produces a faint odor.

Hexyldecyl stearate is soluble in many organic solvents, although Hexyldecyl stearate is insoluble in water and Hexyldecyl stearate can also dissolve other substances.
When applied to the skin, Hexyldecyl stearate will leave a thin coating upon drying.
Hexyldecyl stearate also reduces the thickness of lipsticks.

Handling and Storage of Hexyldecyl Stearate:

Handling:
Avoid prolonged or repeated contact with skin.
Use appropriate personal protective equipment.
Keep away from sources of ignition.

Storage:
Store in a cool, dry, well-ventilated area away from heat and open flames.
Keep containers tightly closed when not in use.
Ensure that storage facilities are equipped to handle spills and leaks.

Hexyldecyl stearate at normal temperatures and provide adequate ventilation.
Keep Hexyldecyl stearate from contacting oxidizing agents and observe all local regulations regarding safe product disposal.

Reactivity of Hexyldecyl Stearate:

Chemical Stability:
Hexyldecyl Stearate is generally stable under normal conditions.

Conditions to Avoid:
Avoid exposure to high temperatures, flames, and oxidizing conditions.

Incompatible Materials:
Strong oxidizing agents and acids may react with Hexyldecyl Stearate.

Hazardous Decomposition Products:
Decomposition may produce carbon oxides and other potentially harmful substances.

Safety of Hexyldecyl Stearate:
The Hexyldecyl stearate safety sheet indicates this chemical product is not hazardous.
However, Hexyldecyl stearate can cause irritation to the eyes or when ingested, although Hexyldecyl stearate is unlikely to cause skin irritation.
Hexyldecyl stearate will remain stable under typical handling and working conditions.

First Aid Measures of Hexyldecyl Stearate:

Inhalation:
Move the person to fresh air.
If breathing is difficult, administer oxygen and seek medical attention.

Skin Contact:
Wash the affected area with soap and water.
Remove contaminated clothing and seek medical attention if irritation persists.

Eye Contact:
Rinse eyes with plenty of water for at least 15 minutes, holding the eyelids open.
Seek medical attention if irritation persists.

Ingestion:
Do not induce vomiting.
Rinse mouth and drink plenty of water.
Seek medical attention immediately.

Fire Fighting Measures of Hexyldecyl Stearate:

Fire Extinguishing Media:
Use foam, dry chemical, carbon dioxide (CO2), or water spray to extinguish fires.

Fire Fighting Procedures:
Wear self-contained breathing apparatus (SCBA) and protective clothing.
Cool containers with water spray to prevent rupture.

Hazards:
Combustion may produce fumes of carbon oxides and other hazardous compounds.
Avoid inhalation of smoke.

Accidental Release Measures of Hexyldecyl Stearate:

Personal Precautions:
Wear appropriate protective equipment, including gloves and goggles.
Ensure adequate ventilation.

Containment:
Prevent spillage from entering drains or waterways.
Contain the spill with absorbent materials such as sand or earth.

Cleanup:
Collect and dispose of the spilled material in accordance with local regulations.
Clean the area with detergent and water.

Exposure Control/Personal Protection of Hexyldecyl Stearate:

Occupational Exposure Limits:
No specific exposure limits are generally established for Hexyldecyl Stearate, but ensure exposure is minimized.

Engineering Controls:
Use in well-ventilated areas.
Employ local exhaust ventilation if necessary.

Personal Protective Equipment (PPE):

Respiratory Protection:
Use a respirator with a filter if exposure limits are exceeded or if there is insufficient ventilation.

Hand Protection:
Wear protective gloves to prevent skin contact.

Eye Protection:
Use safety goggles or face shields to protect against splashes.

Skin Protection:
Wear protective clothing as necessary to prevent skin exposure.

Identifiers of Hexyldecyl Stearate:
CAS No.: 22047-49-0
Chemical Name: 2-ETHYLHEXYL STEARATE
CBNumber: CB8120607
Molecular Formula: C26H52O2
Molecular Weight: 396.69
MDL Number: MFCD00072275

Properties of Hexyldecyl Stearate:
Appearance @ 20°C: Clear to light yellow liquid
Acid value (MGKOH/G): 1 Maximum
Saponification value: 142-156
Iodine value (WIJS): 1 Maximum
Hydroxyl value (MGKOH/G): 3 Maximum
Refractive index @ 25°C: 1.445-1.448
Specific gravity @25°C: 0.850-0.860

Density: 0.86g/cm3
Boiling Point: 438.7ºC at 760mmHg
Molecular Formula: C26H52O2
Molecular Weight: 396.69000
Flash Point: 225.6ºC
Exact Mass: 396.39700
PSA: 26.30000
LogP: 9.15160
Vapour Pressure: 6.79E-08mmHg at 25°C
Index of Refraction: 1.451

Boiling point: 420.33°C (rough estimate)
Density: 0.8789 (rough estimate)
vapor pressure: 0Pa at 20℃
refractive index: 1.4563 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Hexanes (Slightly)
form: Oil
color: Colourless
Specific Gravity: 0.826
InChI: InChI=1S/C26H52O2/c1-4-7-9-10-11-12-13-14-15-16-17-18-19-20-21-23-26(27)28-24-25(6-3)22-8-5-2/h25H,4-24H2,1-3H3
InChIKey: OPJWPPVYCOPDCM-UHFFFAOYSA-N
SMILES: C(OCC(CC)CCCC)(=O)CCCCCCCCCCCCCCCCC
LogP: 11.994 (est)

Molecular Weight: 396.7 g/mol
XLogP3-AA: 11.7
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 23
Exact Mass: 396.396730897 g/mol
Monoisotopic Mass: 396.396730897 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 28
Complexity: 314
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Related Products of Hexyldecyl Stearate:
(2'S)-Nicotine 1-Oxide-d4
rac-Nicotine 1-Oxide-d4
1,7-Dimethyl-1H-imidazo[4,5-g]quinoxalin-2-amine
Disulfoton Sulfone
Disulfoton

Names of Hexyldecyl Stearate:

IUPAC names:
2-ethylhexyl octadecanoate
2-Ethylhexyl Stearate
2-Ethylhexyl stearate
2-ethylhexyl stearate
2-ethylhexyl stearate
LINCOL 60 LINCOL OS
octadecanoic acid, 2-ethylhexyl ester
Octadecanoic acid, 2-ethylhexyl ester + Hexadecanoic acid, 2-ethylhexyl ester
octyl octadecanoate
Viscostatic E20
HEXYLENE GLYCOL
Hexylene Glycol largely acts as a solvent, humectant, and viscosity agent.
Hexylene Glycol′s a category of glycol often utilized as a solvent, humectant, and an agent to control viscosity.
Hexylene Glycol is a clear, colorless liquid chemical compound with the molecular formula C6H14O2.


CAS Number: 107-41-5
EC Number: 203-489-0
MDL number: MFCD00004547
Chem/IUPAC Name: 2-Methylpentane-2,4-diol
Molecular Formula: C6H14O2 or (CH3)2COHCH2CHOHCH3



2-Methyl-2,4-Pentanediol, 2-Methylpentane-2,4-Diol, Diolane, Hexylene Glycol (2-Methyl-2,4-Pentanediol, Isol, Pinakon, MPD, Hexane-1,2-Diol, (4S)-2-Methylpentane-2,4-Diol, (4R)-2-Methylpentane-2,4-Diol, Hexasol, 2,4-dihydroxy-2-methylpentane, 2-methyl-2,4-pentanediol, 4-methyl-2,4-pentanediol, 2-methylpentane-2,4-diol, 2,4-Dihydroxy-2-methylpentane, 2-Methyl-2,4-pentanediol, 4-Methyl-2,4-pentanediol, 2-Methylpentane-2,4-diol, 2,4-Pentanediol, 2-methyl-, α,α,α'-Trimethyltrimethylene glycol, Diolane, Isol, 1,1,3-Trimethyltrimethylenediol, 2-Methyl-2,4-pentandiol, 2-Methyl-2,4-pentanediol, 2,4-Dihydroxy-2-methylpentane, 4-Methyl-2,4-pentanediol, 2-Methyl pentane-2,4-diol, 2-Methylpentan-2,4-diol, Pinakon, 4-Methyl-2,4-pentanediole, (.+/-.)-2-Methyl-2,4-pentanediol, NSC 8098, Isophthalic acid, 2-Methyl-2,4-pentanediol1,1,3-Trimethyltrimethylenediol2,4-Dihydroxy-2-methylpentane2-Methyl pentane-2,4-diol4-Methyl-2,4-pentanediolTrimethyltrimethylene glycolDiolaneIsolPinakonHexG, (2,4-dihydroxy-2-methylpentane, 2,4-pentanediol, 2-methyl-, 2-methylpentane-2,4-diol, 4-methyl-2,4-pentanediol, alpha,alpha,alpha’-trimethyltrimethylene glycol, diolane, hexylene glycol, isol, pinakon, 2,4-Pentanediol,2-methyl-, 2-Methyl-2,4-pentanediol, 2,4-Dihydroxy-2-methylpentane, Diolane, Hexylene glycol, Isol, α,α,α′-Trimethyltrimethylene glycol, 1,1,3-Trimethyltrimethylenediol, MPD, (±)-2-Methyl-2,4-pentanediol, NSC 8098, Hexasol, Isohexanediol, 99113-75-4, 2-furanmethanol, 2-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, Hexylene glycol, 2-METHYL-2,4-PENTANEDIOL, 107-41-5, 2-Methylpentane-2,4-diol, Diolane, Pinakon, 2,4-Pentanediol, 2-methyl-, 2,4-Dihydroxy-2-methylpentane, Isol, 4-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, Caswell No. 574, 2-Methyl pentane-2,4-diol, 2-Methyl-2,4-pentandiol, hexyleneglycol, HSDB 1126, UNII-KEH0A3F75J, (+-)-2-Methyl-2,4-pentanediol, NSC 8098, NSC-8098, EINECS 203-489-0, KEH0A3F75J, alpha,alpha,alpha'-Trimethyltrimethylene glycol, EPA Pesticide Chemical Code 068601, BRN 1098298, 1,3-dimethyl-3-hydroxybutanol, CCRIS 9439, DTXSID5021885, CHEBI:62995, AI3-00919, Hexylene glycol [NF], 1,3,3-trimethyl-1,3-propanediol, TRACID RUBINE 5BL, DTXCID101885, EC 203-489-0, 1,1,3-trimethyl-1,3-propanediol, 4-01-00-02565 (Beilstein Handbook Reference), Hexylene glycol (NF), 7-MethylAtracuriumDimesylate(MixtureofDiastereomers), MPD, CAS-107-41-5, 2-Methylpentan-2,4-diol, 2-Methyl-pentane-2,4-diol, 64229-01-2, MFCD00004547, Hexylene glycol, 99%, R-(-)-2-METHYL-2,4-PENTANEDIOL, 2methyl-2,4-pentanediol, Hexylene glycol, >=99%, Hexylene glycol, 99.5%, SCHEMBL19379, 1,3-Trimethyltrimethylenediol, CHEMBL2104293, NSC8098, (?)-2-Methyl-2,4-pentanediol, SVTBMSDMJJWYQN-UHFFFAOYSA-N, HMS3264E19, HY-B0903, Hexylene glycol, analytical standard, Tox21_201975, Tox21_302818, s3588, AKOS015901459, CCG-213719, WLN: QY1 & 1XQ1 & 1, NCGC00249143-01, NCGC00256494-01, NCGC00259524-01, AC-13749, AS-58339, Hexylene glycol, BioXtra, >=99% (GC), (+/-)-2-Methyl-2,4-pentanediol, MPD, FT-0605050, FT-0605756, FT-0613069, Hexylene glycol, puriss., >=99.0% (GC), M0384, (S)-(-)-2-METHYL-2,4-PENTANEDIOL, .alpha.,.alpha.'-Trimethyltrimethylene glycol, Hexylene glycol, BioUltra, >=99.0% (GC), D04439, EN300-170052, AB01563179_01, J-640306, J-660006, Q2792203, W-108748, Z1255485267, Hexylene glycol, United States Pharmacopeia (USP) Reference Standard, Diolane, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, MPD, MVD, FP17780, NSC 66498, Einecs 227-150-, 3-Methylpentanediol-2,4, 2-METHYLPENTANE-2,4-DIOL, 3-METHYL-2,4-PENTANEDIOL, 3-methyl-pentane-2,4-diol, 2,4-Pentanediol, 3-methyl-, HGL, Diolane, Isol, Pinakon, 1,1,3-Trimethyl-Triethylenediol, Diacetone Glycol, Methylamilene Glycol, 2,4-Dihydroxy-2- Methyl-Penthane, 2-Methyl-Penthane-2,4-Diol., (+-)-2-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, 2,4-Pentanediol, 2-methyl-, 2-Methyl pentane-2,4-diol, 2-Methyl-2,4-pentanediol, 4-Methyl-2,4-pentanediol, Diolane, Hexylene glycol, Isol, Pinakon, alpha,alpha,alpha'-Trimethyltrimethylene glycol, HGL, 1, 1, 3-Trimethyl-Triethylenediol, Diacetone Glycol, Methylamilene Glycol, 2, 4-Dihydroxy-2-Methyl-Penthane, 2-Methyl-Penthane-2, 4-Diol, 2-Hexyl-1,3-dioxolan-2-one, Hexylene Glycol, HG, 2,4-Dihydroxy-2-methylpentane, 2-Methyl-2,4-, pentanediol, 2-Methylpentane-2,4-diol, Pentane-2,4-, diol, 2-methyl,



Hexylene Glycol also has a low viscosity that makes it easier to incorporate.
The chemical formula of Hexylene Glycol is C6H14O2.
Hexylene Glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.


Hexylene Glycol is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.
Hexylene Glycol is 2-methyl-2,4-pentanediol.
Hexylene Glycol is used as coupling agent.


Hexylene Glycol offers low flammability and low evaporation rate.
Hexylene Glycol possesses low surface tension.
Hexylene Glycol exhibits very good solvency.


Hexylene Glycol is a clear, colorless liquid that is used in many personal care and cosmetic formulations.
Hexylene Glycol′s a category of glycol often utilized as a solvent, humectant, and an agent to control viscosity.
Hexylene Glycol, alternative to PG or DEG or MEG in paint formulation in lowering total VOC content.


Hexylene Glycol is a small molecular weight surfactant, widely used as an industrial coating solvent, does not cause adverse health or environmental effects.
Hexylene Glycol is commonly used in the cosmetic and personal care industry, where it functions as a solvent and a humectant in products like moisturisers, lotions, and hair care products.


Additionally, Hexylene Glycol has applications in perfumes, as a fragrance fixative, and in the production of various chemicals and coatings.
Hexylene Glycol is famous for its excellent solvency among a wide variety of materials and is popular in skin care formulas due to its ability to improve the texture.


Hexylene Glycol has viscosity-reducing properties that allow it to thin out heavy, thick formulations and produce smooth spreadability.
Studies indicate Hexylene Glycol also exhibits antimicrobial properties.
Hexylene Glycol floats and mixes slowly with water.


Hexylene Glycol is a clear, colorless liquid.
The principal end uses of Hexylene Glycol include industrial solvent, chemical intermediate, cosmetics, excipient in pharmaceuticals, paints and coatings.
Hexylene Glycol is available in technical grade and NF grade.


Hexylene Glycol is an oxygenated solvent derived from acetone which has two alcohol functions.
Hexylene Glycol has a low evaporation rate and it is completely miscible with water.
Hexylene Glycol largely acts as a solvent, humectant, and viscosity agent.


Decades of research have established Hexylene Glycol as a safe and effective ingredient.
Hexylene Glycol dissolves other ingredients in a product and enhances its stability and texture.
Hexylene Glycol is considered safe for use in cosmetics when used in compliance with regulations and guidelines.


Hexylene Glycol is a diol (with two hydroxy groups at 2 and 4 positions), a colorless liquid with a mildly sweet odor and oily consistency.
In nature, Hexylene Glycol is found in the tobacco plant (Nicotiana tabacum).
For industrial purposes Hexylene Glycol is formed from the achiral reagents, diacetone alcohol, and hydrogen, producing equal amounts of enantiomeric products.


Commercial Hexylene Glycol contains > 99% 2-methyl-2,4-pentanediol and is described as a racemic mixture containing equal amounts of two enantiomers.
Hexylene Glycol is a small molecular weight surfactant.
Hexylene Glycol also goes by its chemical compound name: 2-Methyl-2,4-pentanediol.


As a raw material, Hexylene Glycol is a clear liquid.
Hexylene Glycol is safe for pregnant women and does not cause allergies.
Hexylene Glycol is a biodegradable, colorless liquid that is miscible with water and mainly used as a solvent or coupling agent


Hexylene Glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.
Hexylene Glycol is fully miscible in water and has the chemical formula C6H14O2.
Hexylene Glycol is a compound that appears in a large number of products that are used commercially and industrially.


Hexylene Glycol is a clear, practically colorless, liquid.
Hexylene Glycol is characterized as a clear, colorless, and odorless liquid that finds extensive use in numerous industries, such as cosmetics and personal care products.


Hexylene Glycol helps to maintain moisture and improve the texture of these products.
Hexylene Glycol is considered safe for use in cosmetics when used in accordance with regulations and guidelines.
Hexylene Glycol is a chemical compound used in various industries, including cosmetics and personal care products.


Hexylene Glycol serves as a solvent and a humectant in these products, helping to retain moisture and improve their texture.
2-methylpentane-2,4-diol is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).
Hexylene Glycol, also known as 2-Methyl-2,4-pentanediol, is an organic compound that can be classified as a glycol.


Glycols are a class of alcohols that contain two hydroxyl groups, which can also be called a diols.
Hexylene Glycol is a clear, hygroscopic liquid with a mild, sweet odor.
Hexylene Glycol is most often synthetically produced.


Hexylene Glycol is manufactured by the condensation of 2 molecules of acetone to produce diacetone alcohol, which is further hydrogenated to produce Hexylene Glycol.
This is then purified.


Hexylene Glycol is a clear, colorless liquid chemical compound with the molecular formula C6H14O2.
Hexylene Glycol belongs to a class of chemicals known as glycols, which are often used as solvents, humectants, and chemical intermediates in various industrial applications.


Hexylene Glycol, from Solvay, is an oxygenated solvent derived from acetone which has two alcohol functions.
This speciality ingredient, Hexylene Glycol, demonstrates a low evaporation rate and is completely miscible with water.
Hexylene Glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.


Hexylene Glycol has the chemical formula C6H14O2 and is fully miscible in water.
Hexylene Glycol is an ingredient used in skincare and cosmetic products to help improve the texture and sensory feel of the formulation.
Hexylene Glycol functions as a surfactant, emulsifier, and a viscosity-reducing agent.


Hexylene Glycol is an oily colorless liquid with a mild sweet odor.
Hexylene Glycol floats and mixes slowly with water.
Hexylene Glycol is an oily colorless liquid with a mild sweet odor.


Hexylene Glycol is fully miscible in water and has the chemical formula C6H14O2.
Hexylene Glycol is a compound that appears in a large number of products that are used commercially and industrially
Hexylene Glycol has a low evaporation rate and it is completely miscible with water.


Similar to other glycols, Hexylene Glycol's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable.
Hexylene Glycol is a synthetic substance added to many cosmetics.
Hexylene Glycol is an aroma compound and has a preservative effect.


At the same time, Hexylene Glycol is also a cleaning agent and detergent.
The most important, however, is the emulsifying property of this glycol.
It is thanks to this that Hexylene Glycol has an influence on the consistency of the product.



USES and APPLICATIONS of HEXYLENE GLYCOL:
Hexylene Glycol is mainly used as a solvent or coupling agent.
Hexylene Glycol is a potential substitute for glycol ethers.
Hexylene Glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.


Hexylene Glycol can also be used as a building block in chemical synthesis.
In addition to skin care, Hexylene Glycol is used in other beauty products including hair care and makeup.
Hexylene Glycol has been backed as a safe ingredient for decades with reported concentrations up to 25% in personal care products (though most skin care formulas use much lower amounts than that, especially in preservative blends).


That’s why Hexylene Glycol is commonly used in many cosmetics, e.g. shampoos, shower gels, and soaps.
Thanks to Hexylene Glycol, products are better adapted to the needs of consumers and meet their expectations.
Therefore, the addition of Hexylene Glycol can turn an ordinary cosmetic into something that will be used with real pleasure.


Hexylene Glycol is a compound that appears in a large number of products that are used commercially and industrially.
Hexylene Glycol is used widely across skincare, hair care, and makeup to enhance spreadability, thin out overly thick formulas, and ensure actives are fully dissolved and dispersed.


Hexylene Glycol also has some antimicrobial effect and can enhance the efficacy of certain preservatives.
Hexylene Glycol is used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products at concentrations ranging from 0.1% – 25%.


Hexylene Glycol as a surfactant helps to cleanse and moisturize the skin as well as thinning out the formulation to improve absorption, texture and allow other ingredients to work better.
Hexylene Glycol is also used as a chemical intermediate in chemical syntheses, downhole lubricant for natural gas and oil fields, hydraulic fluid, antifreeze, fuel additive, the solvent in dyes and inks, leather and textile processing, industrial and household cleaners, and in cosmetics.


Hexylene Glycol is also used as a chemical intermediate, which accounts for approximately 20% of its consumption, and another 10% is used on oil and natural-gas fields where it is both a down hole lubricant, and a grinding and extraction aid.
Hexylene Glycol is also employed as an antifreeze, and as a coupling agent for hydraulic fluids.


Hexylene Glycol is a moisturising, and setting, agent in the manufacture of textiles and can also be found in the cosmetics industry where it is a component of fragrances and bath, hair, and soap preparations.
Hexylene Glycol also has a role as a wetting agent in pesticide formulations and is a solvent in the preparation of dyes.


Hexylene Glycol is used for pesticide stabilizer, diesel antifreezer, solvent, spicery, disinfectant,fabric penetration agent and coupler , paper and leather processing auxiliary agent, emulsifier, the additive of fuel and lubricant, etc.
Hexylene Glycol is mainly used as a solvent or coupling agent.


Hexylene Glycol is a potential substitute for glycol ethers.
Hexylene Glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexylene Glycol can also be used as a building block in chemical synthesis.


Hexylene Glycol is a highly soluble advanced organic solvent, which can be used in the production of metal surface treatment agents, rust and oil removal additives, textile auxiliaries, coatings and latex paints, cosmetics, pesticides, biochemical engineering, photosensitive materials, synthetic perfumes and other fields.


Hexylene Glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexylene Glycol can also be used as a building block in chemical synthesis.
Hexylene Glycol is mainly used as a solvent or coupling agent.


Moreover, Hexylene Glycol acts as a reagent in the synthesis of diverse chemicals.
With regard to scientific research applications, Hexylene Glycol serves as a solvent to extract an array of compounds from plant and animal tissues.
Hexylene Glycol′s also employed as a reagent in the creation of various chemicals, including agrochemicals and fragrances.


The largest end use for Hexylene Glycol is in industrial coatings, as a solvent plasticizer in varnishes, lacquers, paints, and paint strippers, accounting for about 45% of the total production.
Hexylene Glycol is often used in preservative blends that contain phenoxyethanol because it boosts the efficacy of this preservative, allowing lower amounts to be used, which reduces the risk skin will have a sensitised response.


Hexylene Glycol is a cosmetic material for FDA regulated product use.
In cosmetics and personal care products, these ingredients are used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.


In the realm of cosmetics and personal care products, Hexylene Glycol functions as a preservative.
Hexylene Glycol′s a humectant that aids in skin moisture retention and enhances skin texture and appearance.
Hexylene Glycol operates by forming a barrier on the skin to impede moisture loss.


Additionally, Hexylene Glycol helps to decrease the skin′s surface tension, thereby facilitating the penetration of other ingredients into the skin.
Hexylene Glycol is mainly used as a solvent or coupling agent.
Hexylene Glycol is a potential substitute for glycol ethers.



WHAT IS HEXYLENE GLYCOL USED FOR?
Hexylene Glycol serves many functional benefits in skin care, hair care, and cosmetic products.

*Skin care:
Hexylene Glycol is primarily used in skin care to improve the sensory feel and texture of the products.
Hexylene Glycol also attracts and retains moisture on the surface of the skin, keeping it hydrated and nourished.
Hexylene Glycol is often found in products like toners and cleansers


*Hair care:
Hexylene Glycol is used as a viscosity agent and solvent to improve the texture and stability of formulations.
Hexylene Glycol also acts as an emollient in shampoos and conditioners to provide hydration to the shafts


*Cosmetic products:
Hexylene Glycol works to dissolve other ingredients present in a formulation and enhance the texture of the final product.
Since it has low viscosity, Hexylene Glycol is a useful ingredient in products like foundations, primers, and concealers



ORIGIN OF HEXYLENE GLYCOL:
Hexylene Glycol is typically synthesized by the reaction of ethylene oxide with n-butanol or by the hydration of 1,5-hexadiene.
Hexylene Glycol is later purified by distillation or other methods to obtain the final Hexylene Glycol.



WHAT DOES HEXYLENE GLYCOL DO IN A FORMULATION?
*Humectant
*Solvent
*Viscosity controlling



IS HEXYLENE GLYCOL VEGAN?
Hexylene Glycol is considered to be a vegan ingredient as it is made synethically made from oils and natural gas.
If you are looking for a vegan product, always make sure that the other ingredients in Hexylene Glycol are vegan and that the brand is cruelty-free.



SCIENTIFIC FACTS OF HEXYLENE GLYCOL:
Butylene Glycol, or 1,3-Butanediol, dissolves most essential oils and synthetic flavoring substances.
Butylene Glycol, Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are glycols or glycol ethers.
Glycols are a class of alcohols that contain two hydroxyl groups which are also called a diols.



PROPERTIES OF HEXYLENE GLYCOL:
*Purity (% by weight) : ≥ 99,5
*Appearance at 20°C : clear liquid free from suspended materials
*Density at 20°C (g/cm3) : 0,920 - 0,923
*Boiling point at 1013 Pa : 197,5°C
*Flash point (closed cup) : 97°C
*Water solubility at 20°c : complete
*Hansen Solubility Parameters at 25°C: δt = 25,2; δd = 15,8; δp = 8,4; δh = 17



SAFETY PROFILE OF HEXYLENE GLYCOL:
Hexylene Glycol is generally considered safe for use in cosmetic products.
Hexylene Glycol does not cause skin irritation and sensitization and is not known to be comedogenic.
However, as with any ingredient, some individuals may have an allergic reaction or sensitivity to it, so Hexylene Glycol is always recommended to patch test products before use.
Lastly, Hexylene Glycol is vegan and can be considered halal, but it is best to check with the supplier.



ALTERNATIVES OF HEXYLENE GLYCOL:
*PROPYLENE GLYCOL,
*BUTYLENE GLYCOL,
*GLYCERIN



HOW IS HEXYLENE GLYCOL PRODUCED?
Hexylene Glycol is formed from the achiral reagents hydrogen and diacetone alcohol.



HOW IS HEXYLENE GLYCOL STORED AND DISTRIBUTED?
Hexylene Glycol is stored in bulk storage or stainless steel drums and is transported by tank truck.
Hexylene Glycol is classed as non-hazardous for air, sea, and road freight but is classed as an irritant.
Hexylene Glycol has a specific gravity of 0.925 and a flash point of 93 °C (closed cup).



WHAT IS HEXYLENE GLYCOL USED FOR?
The single largest user of Hexylene Glycol is the industrial coatings industry which uses approximately 45% of the HGL produced world-wide.
Hexylene Glycol is a component in lacquers and varnishes, and is a solvent plasticiser in surface coatings.
Hexylene Glycol is also a component in both oil and water- based paints, and in paint strippers.



HEXYLENE GLYCOL AT A GLANCE:
*Solvent that produces smooth spreadability and pleasing skin care textures
*Viscosity-reducing properties allow Hexylene Glycol to thin out heavy, thick formulations
*Shows up in a wide variety of skin care, hair care, and makeup products
*As a raw material, Hexylene Glycol is clear liquid
*Backed by decades of research as a safe ingredient



BENEFITS OF HEXYLENE GLYCOL:
Hexylene Glycol offers several benefits in various applications, particularly in cosmetics and personal care products:

*Humectant:
Hexylene Glycol helps to retain moisture, which is essential for skin and hair health.
Hexylene Glycol can keep these products from drying out, ensuring that they remain effective and pleasant to use.

*Solvent:
Hexylene Glycol functions as a solvent, helping to dissolve and blend other ingredients in cosmetics and personal care products.
This facilitates the formulation of moisturisers, lotions, and other beauty products.

*Texture Improvement:
Hexylene Glycol can enhance the texture of skincare and hair care products, making them smoother and easier to apply.
This contributes to a more luxurious and user-friendly experience.

*Fragrance Fixative:
In the perfume industry, Hexylene Glycol is used as a fixative, helping to stabilize and prolong the scent of fragrances.
This ensures that the fragrance remains consistent and long-lasting.

*Skin-Friendly:
Hexylene Glycol is considered safe for use in cosmetics and personal care products, as it has low skin irritation potential.
Hexylene Glycol is typically well-tolerated by most individuals.

*Versatility:
Its versatility makes Hexylene Glycol suitable for a wide range of products, including moisturizers, shampoos, conditioners, and perfumes.



IS HEXYLENE GLYCOL SAFE?
The safety of Hexylene Glycol has been assessed by the Cosmetic Ingredient Review Expert Panel.
The Cosmetic Ingredient Review Expert Panel is responsible for the independent evaluation of the safety and efficacy of skincare and cosmetic ingredients.
The Expert Panel evaluated the scientific data and concluded that Hexylene Glycol is safe for use in cosmetics and personal care products.



FEATURES OF HEXYLENE GLYCOL:
*Solvent,
*intermediate



THE GOOD:
Hexylene Glycol helps to improve the texture and feel of skincare and cosmetic formulations.
Hexylene Glycol also has an added benefit of acting as a protective barrier for the skin.


THE NOT SO GOOD:
Hexylene Glycol can be a mild irritant in high concentrations.


WHO IS HEXYLENE GLYCOL FOR?
All skin types except those that have an identified allergy to Hexylene Glycol.


SYNERGETIC INGREDIENTS:
Hexylene Glycol works well with most ingredients.


KEEP AN EYE ON:
Nothing to keep an eye on here.



WHAT ARE THE FUNCTIONS OF HEXYLENE GLYCOL?
Hexylene Glycol is added to cosmetics and skincare products based on its functions as a surfactant, an emulsifier, and a viscosity-reducing agent.

*SURFACTANT
Surfactant is the short term for surface active agents.
Surfactants are compounds that lower the surface tension between two substances.
In skincare products, surfactants work to lift dirt, oil and fats from the skin, allowing them to be washed away.

This is possible because while one end of the surfactant molecule is attracted to water, the other end is attracted to oil.
Thus, surfactants attract the oil, dirt, and other impurities that have accumulated on your skin during the day and wash them away.
Due to these properties, Hexylene Glycol can be found in many different cleansers and body washes.


*EMULSIFIER
Hexylene Glycol also functions as an emulsifier.
An emulsifier is needed for products that contain both water and oil components, for example, when oils are added to a water-based formula.
When shaking stops, however, the two phases can start to separate.

To address this problem, an emulsifier like Hexylene Glycol can be added to the system, which helps the droplets remain dispersed and produces an even and stable formulation.

As an emulsifier, Hexylene Glycol consists of a water-loving hydrophilic head and an oil-loving hydrophobic tail.
The hydrophilic head is attracted to the water and the hydrophobic tail to the oil.
Once again, Hexylene Glycol reduces the surface tension by positioning itself between the oil and water, which has a stabilizing effect on the product.


*THINNING
Finally, Hexylene Glycol functions as a viscosity-reducing agent.
The term viscosity corresponds to the concept of “thickness”, for example, honey has a higher viscosity than water.
As a viscosity-reducing agent, Hexylene Glycol works to thin out heavy formulations and create a thinner, more spreadable product.



PHYSICAL and CHEMICAL PROPERTIES of HEXYLENE GLYCOL:
Molecular Weight: 118.174
Exact Mass: 118.17
EC Number: 203-489-0
ICSC Number: 0660
NSC Number: 8098
UN Number: 1993
DSSTox ID: DTXSID5021885
Color/Form: Liquid|Colorless liquid
HScode: 2905399090
PSA: 40.46000
Boiling Point: 197.5°C
Melting Point: -50°C
pH: 7.0

Solubility: Highly soluble in water
Viscosity: Low
XLogP3: 0.00
Appearance: Hexylene glycol is an oily colorless liquid with a mild sweet odor.
Floats and mixes slowly with water.
Density: 0.92 g/cm3
Melting Point:-50 °C
Boiling Point:198 °C @ Press: 760 Torr
Flash Point:93.9±0.0 °C
Refractive Index:1.447
Water Solubility:Miscible
Storage Conditions:Separated from strong oxidants and strong acids.
Vapor Pressure:0.05 mmHg

Vapor Density:
Relative vapour density (air = 1): 4.1
Flammability characteristics: Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Explosive limit: Explosive limits , vol% in air: 1.2-8.1
Odor:Mild sweetish
Henrys Law Constant:
Henry's Law constant = 4.06X10-7 atm-cu m/mol at 25 °C (est)
Experimental Properties:
Dipole moment: 2.8
Heat of formation = -5.3476X10+8 J/kmol
Triple point temperature = 223.15 °C; triple point pressure: 9.5609X10-6 Pa
Hydroxyl radical reaction rate constant = 2.77X10-11 atm-cu m/mol at 25 °C

Air and Water Reactions: Hygroscopic.
Water soluble
Reactive Group:Alcohols and Polyols
Reactivity Profile: HEXYLENE GLYCOL is incompatible with the following:
Strong oxidizers, strong acids.
Autoignition Temperature: 583 °F
Autoignition temp = 579 K|306 °C
Heat of Combustion: Standard net heat of combustion = -3.4356x10+9 J/kmol
Flammable Limits: Flammability limits = 1.3-9 vol%
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Heat of Vaporization: 13.7 kcal/mol at the boiling point
Critical Temperature & Pressure:
Critical temp = 621 K
Critical pressure = 4.01X10+6 Pa

Molecular Weight: 118.17
XLogP3-AA: 0.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 118.099379685
Monoisotopic Mass: 118.099379685
Topological Polar Surface Area: 40.5 Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 68.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical name (CAS): 2-methyl-2,4-pentanediol
CAS number: 107-41-5
Structural formula: CH3–CH(OH)–CH2–C(OH)(CH3)2
Molecular formula: C6H14O2
Molecular weight: 118.18
Melting point: –40°C
Boiling point: 195–200°C
Density at 20°C: 0.920–0.923 g/cm3
Vapour pressure at: 20°C 0.06 hPa
log Pow*: –0.14
CAS number: 107-41-5
EC index number: 603-053-00-3
EC number: 203-489-0
Grade: NF

Hill Formula: C₆H₁₄O₂
Molar Mass: 118.18 g/mol
HS Code: 2926 90 70
Density: 0.922 g/cm3 (20 °C)
Explosion limit: 1 - 9.9 %(V)
Flash point: 94 °C
Ignition temperature: 425 °C
Melting Point: -40 °C
pH value: 6.0 - 8.0 (118.2 g/l, H₂O, 25 °C)
Vapor pressure: 0.03 hPa (20 °C)
Physical state: liquid
Color: colorless
Odor: sweet, mild
Melting point/freezing point:
Melting point/range: -40 °C - lit.

Initial boiling point and boiling range: 197 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 7,4 %(V)
Lower explosion limit: 1,3 %(V)
Flash point: 94 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 6,0 - 8,0 at 118,2 g/l at 25 °C
Solubility:
Easily soluble in cold water.
Soluble in diethyl ether.
Soluble in alcohol, lower aliphatic hydrocarbons.
Soluble in a variety of organic solvents.
Miscible with fatty acids
Specific Gravity 20/20 °C:0.9232

Distillation Range at 760 mm Hg (IP) °C:196.4
Distillation Range at 760 mm Hg (DP) °C:198.2
Purity, % w/w:99.62
Acidity as acetic Acid, % w/w: 0.0010
Water, % w/w: 0.018
Melting point: −40 °C(lit.)
Boiling point: 197 °C(lit.)
Density: 0.925 g/mL at 25 °C(lit.)
vapor density: 4.1 (vs air)
vapor pressure: 0.02 mm Hg ( 20 °C)
refractive index: n20/D 1.427(lit.)
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 36 mPa.s at 20 °C

Water solubility ca.: 118,2 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,58 - (Lit.), Bioaccumulation is not expected.
Vapor pressure: 0,03 hPa at 20 °C
Density: 0,925 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information
Relative vapor density: 4,08 - (Air = 1.0)
Molar Weight: 118.176g/mol
Melting Point: -40 °C
Boiling Point: 196 °C

Flash Point: 93 °C
Density: 0.925
Forms: Liquid (clear)
Chemical formula: C6H14O2
Molar mass: 118.176 g•mol−1
Appearance: colourless liquid
Odor: mild, sweetish
Density: 0.92 g/mL
Melting point: −40 °C (−40 °F; 233 K)
Boiling point: 197 °C (387 °F; 470 K)
Solubility in water: miscible[1]
Vapor pressure: 0.05 mmHg (20°C)
Flash point: 98.3 °C (208.9 °F; 371.4 K)
Explosive limits: 1.3%-7.4%
Appearance: colorless clear liquid (est)
Physical state and Appearance:Liquid.

Odor:Sweetish
Molecular Weight:118.18 g/mole
Color:Colorless
Boiling Point:197 (386.6) - 198° C
Melting Point:-50 - (-58)
Specific Gravity:0.9254 @ 17 C; 0.9234 @ 20 C (Water = 1)
Vapor Pressure: 0.05 mm of Hg (@ 20)
Vapor Density: 4.1 (Air = 1)
Odor Threshold: 50 ppm
Dispersion Properties: See solubility in water, diethyl ether
Flash point: 201 °F
storage temp.: 2-8°C
solubility: H2O: 1 M at 20 °C, clear, colorless
pka: 14.72±0.20(Predicted)
CAS DataBase Reference: 5683-44-3(CAS DataBase Reference)

Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92400 @ 25.00 °C.
Melting Point: -40.00 °C. @ 760.00 mm Hg
Boiling Point: 197.00 to 199.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.096000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.1 ( Air = 1 )
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 0.004 (est)
Soluble in: alcohol
water, 3.256e+004 mg/L @ 25 °C (est)
water, 1.00E+06 mg/L @ 25 °C (exp)
Molecular Weight: 118.2 g/mol
Empirical Formula: C6H14O2

Appearance: Colorless, Liquid
Freezing Point: -50°C (-58.0°F)
Boiling Point: @ 760mm Hg 196°C (385°F)
Flash Point: Closed Cup 96°C (205°F)
Autoignition Temperature: 425°C (797°F)
Density @ 20°C: 0.924 kg/L, 7.71 lb/gal
Vapor Pressure: @ 20°C 0.05 mmHg
Evaporation Rate: (nBuAc = 1) 0.007
Solubility in Water: @ 20°C Miscible
Surface Tension @ 20°C: 33.1 dynes/cm
Refractive Index @ 20°C: 1.426
Viscosity @ 20°C: 38.9 cP
Lower Explosive Limit: 1.0 v/v%
Upper Explosive Limit: 9.9 v/v%
Conductivity @ 20°C: 3x106 pS/m

Dielectric Constant @ 20°C: ≈7.7
Specific Heat @ 20°C: 2.20 kJ/kg/°C
Heat of Vaporization @ normal boiling point: 435 kJ/kg
Heat of Combustion @ 25°C: 29875 kJ/kg
Odor Threshold: 50 ppm
Molecular Weight 118.2 g/mol
Empirical Formula C6H14O2
Appearance Colorless
Liquid
Freezing Point -50°C (-58.0°F)
Boiling Point @ 760mm Hg 196°C (385°F)
Flash Point – Closed Cup 96°C (205°F)
Autoignition Temperature 425°C (797°F)

Density @ 20°C 0.924 kg/L
7.71 lb/gal
Vapor Pressure @ 20°C 0.05 mmHg
Evaporation Rate (nBuAc = 1) 0.007
Solubility in Water @ 20°C Miscible
Surface Tension @ 20°C 33.1 dynes/cm
Refractive Index @ 20°C 1.426
Viscosity @ 20°C 38.9 cP
Lower Explosive Limit 1.0 v/v%
Upper Explosive Limit 9.9 v/v%
Conductivity @ 20°C 3x106 pS/m
Dielectric Constant @ 20°C ≈7.7
Specific Heat @ 20°C 2.20 kJ/kg/°C

Heat of Vaporization @ normal boiling point 435 kJ/kg
Heat of Combustion @ 25°C 29875 kJ/kg
Odor Threshold 50 ppm
CAS NO:107-41-5
EINECS NO:203-489-0
Molecular Formula:C6H14O2
Molecular Weight:118.1742
InChI:InChI=1/C6H14O2/c1-5(7)4-6(2,3)8/h5,7-8H,4H2,1-3H3
Density:0.96g/cm3
Melting Point:-40ºC
Boiling Point:197.5°C at 760 mmHg
Flash Point:93.9°C
Water Solubility:soluble
Vapour Pressure:0.0961mmHg at 25°C

Refractive Rate:n20/D1.427(lit.)
Storage Condition:2-8°C
Appearance:Clear colorless Slightly Viscous Liquid
Odor:Ammonia-like
PH Value:6-8(25ºC,1MinH2O)
Explosive Limit:1-9.9%(V)
Sensitivity:Hygroscopic
Stability: Incompatible with strong oxidizing agents, strong acids,strong reducing agents.
Physical description: Colorless liquid with a mild, sweetish odor.
Boiling point: 388°F
Molecular weight: 118.2
Freezing point/melting point: -58°F (sets to glass)
Vapor pressure: 0.05 mmHg
Flash point: 209°F
Specific gravity: 0.923

Lower explosive limit (LEL): 1.3% (calc)
Upper explosive limit (UEL): 8.1% (calc)
NFPA health rating: 2
NFPA fire rating: 1
NFPA reactivity rating: 0
Appearance: colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92400 @ 25.00 °C.
Melting Point: -40.00 °C. @ 760.00 mm Hg
Boiling Point: 197.00 to 199.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.096000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.1 ( Air = 1 )
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 0.004 (est)
Soluble in: alcohol
water, 3.256e+004 mg/L @ 25 °C (est)
water, 1.00E+06 mg/L @ 25 °C (exp)



FIRST AID MEASURES of HEXYLENE GLYCOL:
-Description of first-aid measures:
*General advice
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXYLENE GLYCOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXYLENE GLYCOL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXYLENE GLYCOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 240 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXYLENE GLYCOL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Store under inert gas.
Hygroscopic.



STABILITY and REACTIVITY of HEXYLENE GLYCOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


HEXYLENE GLYCOL
Hexylene glycol is a small molecular weight surfactant.
Hexylene Glycol is an oxygenated solvent derived from acetone which has two alcohol functions.


CAS Number: 107-41-5
EC Number: 203-489-0
MDL number: MFCD00004547
Molecular Formula: C6H14O2 / (CH3)2COHCH2CHOHCH3


Hexylene glycol is a biodegradable, widely-used solution for many markets, including skin and hair care, with Inert Registration (EPA).
Hexylene glycol is an oxygenated solvent derived from acetone which has two alcohol functions.
Hexylene glycol has a low evaporation rate and it is completely miscible with water.


Hexylene glycol is a key solvent in many markets such as coatings, construction, detergency, cosmetics & fragrances, textiles & leather.
Hexylene glycol is a potential substitute for glycol ethers.
Hexylene glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.


Hexylene glycol is an oily colorless liquid with a mild sweet odor.
Hexylene glycol floats and mixes slowly with water.
Hexylene glycol is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).


Hexylene glycol is a natural product found in Nicotiana tabacum with data available.
Hexylene Glycol is a clear, colorless liquid that is used in many personal care and cosmetic formulations.
Hexylene glycol largely acts as a solvent, humectant, and viscosity agent.


Decades of research have established Hexylene Glycol as a safe and effective ingredient.
Hexylene glycol dissolves other ingredients in a product and enhances its stability and texture.
Hexylene glycol also has a low viscosity that makes it easier to incorporate.


The chemical formula of Hexylene Glycol is C6H14O2.
Hexylene Glycol is typically synthesized by the reaction of ethylene oxide with n-butanol or by the hydration of 1,5-hexadiene.
Hexylene glycol is later purified by distillation or other methods to obtain the final Hexylene Glycol.


Similar to other glycols, Hexylene glycol is a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable.
Hexylene Glycol is a liquid with a mild, sweet odor.
Hexylene Glycol or HG is an oxygenated solvent derived from acetone which has two alcohol functions.


Hexylene glycol has a low evaporation rate and it is completely miscible with water.
Hexylene glycol is a potential substitute for glycol ethers.
Hexylene glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.


Hexylene Glycol is a clear, practically colorless, liquid.
Hexylene glycol also goes by its chemical compound name: 2-Methyl-2,4-pentanediol.
As a raw material, Hexylene glycol is a clear liquid.


Hexylene Glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.
Hexylene glycol is fully miscible in water and has the chemical formula C6H14O2.
Hexylene glycol is a compound that appears in a large number of products that are used commercially and industrially.


Hexylene glycol (also known as HGL, 2-methyl pentane-2,4-diol, pinakon and Diolane) is a clear, colourless liquid with a characteristic odour.
Hexylene glycol is fully miscible in water and has the chemical formula C6H14O2.
Hexylene glycol is a compound that appears in a large number of products that are used commercially and industrially.


Hexylene glycol, an analog of hexylene glycol, is a small molecular surfactant which could be useful as an environmentally friendly industrial coating solvent.
Hexylene glycol, an analog of hexylene glycol, is a small molecular surfactant which could be useful as an


Hexylene glycol is an organic compound with two -OH groups, that is why it is called as glycol.
Hexylene glycol comes as clear liquid with mild/ sweet odor.
Hexylene glycol is an ingredient used in skincare and cosmetic products to help improve the texture and sensory feel of the formulation.


Hexylene glycol functions as a surfactant, emulsifier, and a viscosity-reducing agent.
Hexylene glycol, also known as 2-Methyl-2,4-pentanediol, is an organic compound that can be classified as a glycol.
Glycols are a class of alcohols that contain two hydroxyl groups, which can also be called a diols.


Hexylene glycol is a clear, hygroscopic liquid with a mild, sweet odor.
Hexylene glycol is most often synthetically produced.
It is manufactured by the condensation of 2 molecules of acetone to produce diacetone alcohol, which is further hydrogenated to produce hexylene glycol.
This is then purified.


Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics.
Hexylene glycol exhibits antibacterial and antifungal properties.
Hexylene Glycol is a cosmetic material for FDA regulated product use


Hexylene Glycol (HG) is a clear, colorless liquid with a characteristic odor.
Hexylene glycol is available in Industrial grade and NF grade.
Hexylene Glycol is an oxygenated solvent derived from acetone which has two alcohol functions.


This speciality ingredient, Hexylene Glycol, demonstrates a low evaporation rate and is completely miscible with water.
Hexylene Glycol or HG is an oxygenated solvent derived from acetone which has two alcohol functions.



USES and APPLICATIONS of HEXYLENE GLYCOL:
The single largest user of hexylene glycol is the industrial coatings industry which uses approximately 45% of the HGL produced world-wide.
Hexylene glycol is a component in lacquers and varnishes, and is a solvent plasticiser in surface coatings.
Hexylene glycol is also a component in both oil and water- based paints, and in paint strippers.


Hexylene glycol can also be used as a building block in chemical synthesis.
Hexylene glycol is mainly used as a solvent or coupling agent.
Hexylene glycol is used in chemical manufacturing, as a solvent, and in hydraulic fluids.


Hexylene Glycol serves many functional benefits in skin care, hair care, and cosmetic products.
Hexylene glycol is used in Building-light blue, and Concrete and Cement.
Hexylene glycol is mainly used as a solvent or coupling agent.


Hexylene glycol is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.
Hexylene glycol is also used as a chemical intermediate, which accounts for approximately 20% of its consumption, and another 10% is used on oil and natural-gas fields where it is both a down hole lubricant, and a grinding and extraction aid.


Hexylene glycol is also employed as an antifreeze, and as a coupling agent for hydraulic fluids.
Hexylene glycol is a moisturising, and setting, agent in the manufacture of textiles and can also be found in the cosmetics industry where it is a component of fragrances and bath, hair, and soap preparations.


Hexylene glycol also has a role as a wetting agent in pesticide formulations and is a solvent in the preparation of dyes.
Hexylene glycol is mainly used as a solvent or coupling agent.
Hexylene glycol is a potential substitute for glycol ethers.


Hexylene glycol is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexylene glycol can also be used as a building block in chemical synthesis.
Hexylene glycol is famous for its excellent solvency among a wide variety of materials and is popular in skin care formulas due to its ability to improve the texture.


Hexylene glycol has viscosity-reducing properties that allow it to thin out heavy, thick formulations and produce smooth spreadability.
Studies indicate Hexylene glycol also exhibits antimicrobial properties.
In addition to skin care, hexylene glycol is used in other beauty products including hair care and makeup.


Hexylene glycol is often used in preservative blends that contain phenoxyethanol because it boosts the efficacy of this preservative, allowing lower amounts to be used, which reduces the risk skin will have a sensitised response.
Hexylene glycol has been backed as a safe ingredient for decades with reported concentrations up to 25% in personal care products (though most skin care formulas use much lower amounts than that, especially in preservative blends).


Hexylene glycol (2-methyl-2,4-pentanediol) is a solvent used in many different applications: paints and varnishes, glues and adhesives, inks, and industrial solvents (synthesis, extraction, etc.).
In cosmetics and personal care products, Hexylene glycol is used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.


Hexylene glycol is used as solvent and viscosity decreasing agent in cosmetics and personal care products.
Hexylene glycol is used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products at concentrations ranging from 0.1% – 25%.


Hexylene glycol as a surfactant helps to cleanse and moisturize the skin as well as thinning out the formulation to improve absorption, texture and allow other ingredients to work better.
Hexylene glycol is used Solvent, Chemical Intermediate, Cosmetics, Paints, Coatings.


Hexylene glycol is a small molecular weight surfactant, widely used as an industrial coating solvent, does not cause adverse health or environmental effects.
Hexylene glycol is used as a softening agent, humectant, and solvent in cosmetics and hair care products.


-Skin care uses of Hexylene glycol:
Hexylene glycol is primarily used in skin care to improve the sensory feel and texture of the products.
Hexylene glycol also attracts and retains moisture on the surface of the skin, keeping it hydrated and nourished.
Hexylene glycol is often found in products like toners and cleansers


-Hair care uses of Hexylene glycol:
Hexylene glycol is used as a viscosity agent and solvent to improve the texture and stability of formulations.
Hexylene glycol also acts as an emollient in shampoos and conditioners to provide hydration to the shafts


-Cosmetic products uses of Hexylene glycol:
Hexylene glycol works to dissolve other ingredients present in a formulation and enhance the texture of the final product.
Since Hexylene glycol has low viscosity, it is a useful ingredient in products like foundations, primers, and concealers


-Cosmetic Uses of Hexylene glycol:
*perfuming agents
*skin conditioning
*solvents
*surfactants
*surfactant - emulsifying



USES AND BENEFITS OF HEXYLENE GLYCOL:
Hexylene glycol is a surfactant, emulsifier and viscosity adjusting agent.
The molecule of hexylene glycol has a water-loving head part and oil-loving tail part.
This property makes it an ideal choice as a surfactant and emulsifier.
The emulsifier is meant to hold water and oil together to make the products more stable.
Hexylene glycol is used to decrease the viscosity of the product.
So, in high viscosity product, hexylene glycol is used to “thin” the formulation.



HOW IS HEXYLENE GLYCOL PRODUCED?
Hexylene glycol is formed from the achiral reagents hydrogen and diacetone alcohol.



HOW IS HEXYLENE GLYCOL STORED AND DISTRIBUTED?
Hexylene Glycol is stored in bulk storage or stainless steel drums and is transported by tank truck.
Hexylene glycol is classed as non-hazardous for air, sea, and road freight but is classed as an irritant.
Hexylene glycol has a specific gravity of 0.925 and a flash point of 93 °C (closed cup).



WHAT ARE THE FUNCTIONS OF HEXYLENE GLYCOL?
Hexylene glycol is added to cosmetics and skincare products based on its functions as a surfactant, an emulsifier, and a viscosity-reducing agent.

*Surfactant
Surfactant is the short term for surface active agents.
Surfactants are compounds that lower the surface tension between two substances.
In skincare products, surfactants work to lift dirt, oil and fats from the skin, allowing them to be washed away.

This is possible because while one end of the surfactant molecule is attracted to water, the other end is attracted to oil.
Thus, surfactants attract the oil, dirt, and other impurities that have accumulated on your skin during the day and wash them away.
Due to these properties, hexylene glycol can be found in many different cleansers and body washes.


*Emulsifier
Hexylene glycol also functions as an emulsifier.
An emulsifier is needed for products that contain both water and oil components, for example, when oils are added to a water-based formula.
When water and oil are mixed together and vigorously shaken, a dispersion of oil droplets in water is formed.

When shaking stops, however, the two phases can start to separate.
To address this problem, an emulsifier like hexylene glycol can be added to the system, which helps the droplets remain dispersed and produces an even and stable formulation.

As an emulsifier, hexylene glycol consists of a water-loving hydrophilic head and an oil-loving hydrophobic tail.
The hydrophilic head is attracted to the water and the hydrophobic tail to the oil.
Once again, hexylene glycol reduces the surface tension by positioning itself between the oil and water, which has a stabilizing effect on the product.


*Thinning
Finally, hexylene glycol functions as a viscosity-reducing agent.
The term viscosity corresponds to the concept of “thickness”, for example, honey has a higher viscosity than water.
As a viscosity-reducing agent, hexylene glycol works to thin out heavy formulations and create a thinner, more spreadable product.



WHAT DOES HEXYLENE GLYCOL DO IN A FORMULATION?
*Humectant
*Solvent
*Viscosity controlling



SAFETY PROFILE OF HEXYLENE GLYCOL:
Hexylene Glycol is generally considered safe for use in cosmetic products.
Hexylene glycol does not cause skin irritation and sensitization and is not known to be comedogenic.
Lastly, Hexylene Glycol is vegan and can be considered halal, but it is best to check with the supplier.



HEXYLENE GLYCOL ALTERNATIVES:
*PROPYLENE GLYCOL, BUTYLENE GLYCOL, GLYCERIN



IS HEXYLENE GLYCOL VEGAN?
Hexylene glycol is considered to be a vegan ingredient as it is made synethically made from oils and natural gas.



WHAT ARE SOME PRODUCTS THAT MAY CONTAIN HEXYLENE GLYCOL?
*Moisture creams
*Aftershave products
*Hair colors
*Hair conditioners
*Shampoos



HEXYLENE GLYCOL AT A GLANCE:
*Solvent that produces smooth spreadability and pleasing skin care textures
*Viscosity-reducing properties allow Hexylene glycol to thin out heavy, thick formulations
*Hexylene glycol shows up in a wide variety of skin care, hair care, and makeup products
*As a raw material, Hexylene glycol is clear liquid
*Backed by decades of research as a safe ingredient



FUNCTIONS OF HEXYLENE GLYCOL:
*Emulsifying :
Hexylene glycol promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
*Skin conditioning :
Hexylene glycol maintains skin in good condition
*Solvent :
Hexylene glycol dissolves other substances
*Surfactant :
Hexylene glycol reduces the surface tension of cosmetics and contributes to the even distribution of the product when it is used
*Perfuming :
Hexylene glycol is used for perfume and aromatic raw materials




HEXYLENE GLYCOL, THE GOOD:
Hexylene glycol helps to improve the texture and feel of skincare and cosmetic formulations.
Hexylene glycol also has an added benefit of acting as a protective barrier for the skin.


WHO IS HEXYLENE GLYCOL FOR?
All skin types except those that have an identified allergy to Hexylene glycol.


SYNERGETIC INGREDIENTS OF HEXYLENE GLYCOL:
Hexylene glycol works well with most ingredients.


KEEP AN EYE ON:
Nothing to keep an eye on here.



PHYSICAL and CHEMICAL PROPERTIES of HEXYLENE GLYCOL:
Molecular Weight: 118.17 g/mol
XLogP3-AA: 0.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 118.099379685 g/mol
Monoisotopic Mass: 118.099379685 g/mol
Topological Polar Surface Area: 40.5Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 68.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Boiling Point: 197.5°C
Melting Point: -50°C
pH: 7.0
Solubility: Highly soluble in water
Viscosity: Low
Physical state: liquid
Color: colorless
Odor: sweet, mild
Melting point/freezing point:
Melting point/range: -40 °C - lit.
Initial boiling point and boiling range: 197 °C - lit.
Flammability (solid, gas): No data available

Upper/lower flammability or explosive limits:
Upper explosion limit: 7,4 %(V)
Lower explosion limit: 1,3 %(V)
Flash point: 94 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 6,0 - 8,0 at 118,2 g/l at 25 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 36 mPa.s at 20 °C
Water solubility: ca.118,2 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,58 - (Lit.), Bioaccumulation is not expected.
Vapor pressure: 0,03 hPa at 20 °C
Density: 0,925 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Relative vapor density: 4,08 - (Air = 1.0)
Appearance: colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92400 @ 25.00 °C.
Melting Point: -40.00 °C. @ 760.00 mm Hg
Boiling Point: 197.00 to 199.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.096000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.1 ( Air = 1 )
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 0.004 (est)

Soluble in: alcohol
water, 3.256e+004 mg/L @ 25 °C (est)
water, 1.00E+06 mg/L @ 25 °C (exp)
CAS number: 107-41-5
EC index number: 603-053-00-3
EC number: 203-489-0
Grade: NF
Hill Formula: C₆H₁₄O₂
Molar Mass: 118.18 g/mol
HS Code: 2926 90 70
Density: 0.922 g/cm3 (20 °C)
Explosion limit: 1 - 9.9 %(V)
Flash point: 94 °C
Ignition temperature: 425 °C
Melting Point: -40 °C
pH value: 6.0 - 8.0 (118.2 g/l, H₂O, 25 °C)
Vapor pressure: 0.03 hPa (20 °C)
Boiling point: 388°F
Molecular weight: 118.2
Freezing point/melting point: -58°F (sets to glass)
Vapor pressure: 0.05 mmHg
Flash point: 209°F
Specific gravity: 0.923
Ionization potential:
Lower explosive limit (LEL): 1.3% (calc)
Upper explosive limit (UEL): 8.1% (calc)
NFPA health rating: 2
NFPA fire rating: 1
NFPA reactivity rating: 0
Appearance (Clarity): Clear
Appearance (Colour): Colourless
Appearance (Form): Liquid
Assay (GC): min. 99%
Density (g/ml) @ 20°C: 0.920-0.925
Refractive Index (20°C): 1.427-1.428
Boiling Point: 197°C
Water (KF): max. 0.3%



FIRST AID MEASURES of HEXYLENE GLYCOL:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXYLENE GLYCOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXYLENE GLYCOL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXYLENE GLYCOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 240 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A (acc. to DIN 3181)
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXYLENE GLYCOL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Store under inert gas.
Hygroscopic.



STABILITY and REACTIVITY of HEXYLENE GLYCOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Incompatible materials:
No data available



SYNONYMS:
Hexylene glycol
2-METHYL-2,4-PENTANEDIOL
107-41-5
2-Methylpentane-2,4-diol
Diolane
Pinakon
2,4-Pentanediol, 2-methyl-
2,4-Dihydroxy-2-methylpentane
Isol
4-Methyl-2,4-pentanediol
1,1,3-Trimethyltrimethylenediol
Caswell No. 574
2-Methyl pentane-2,4-diol
2-Methyl-2,4-pentandiol
hexyleneglycol
HSDB 1126
UNII-KEH0A3F75J
(+-)-2-Methyl-2,4-pentanediol
NSC 8098
NSC-8098
EINECS 203-489-0
KEH0A3F75J
alpha,alpha,alpha'-Trimethyltrimethylene glycol
EPA Pesticide Chemical Code 068601
BRN 1098298
1,3-dimethyl-3-hydroxybutanol
CCRIS 9439
DTXSID5021885
CHEBI:62995
AI3-00919
Hexylene glycol [NF]
1,3,3-trimethyl-1,3-propanediol
TRACID RUBINE 5BL
DTXCID101885
EC 203-489-0
1,1,3-trimethyl-1,3-propanediol
4-01-00-02565 (Beilstein Handbook Reference)
MFCD00004547
Hexylene glycol (NF)
HEXYLENE GLYCOL (II)
HEXYLENE GLYCOL [II]
7-MethylAtracuriumDimesylate(MixtureofDiastereomers)
HEXYLENE GLYCOL (MART.)
HEXYLENE GLYCOL [MART.]
HEXYLENE GLYCOL (USP-RS)
HEXYLENE GLYCOL [USP-RS]
CAS-107-41-5
2-Methylpentan-2,4-diol
2-Methyl-pentane-2,4-diol
Hexilenglicol
Hexylne glycol
Hexylene glycol, 99%
R-(-)-2-METHYL-2,4-PENTANEDIOL
2methyl-2,4-pentanediol
2-Metyl-2,4-pentandiol
D06GOK
2-methyl-2-4-pentanediol
Hexylene glycol, >=99%
Hexylene glycol, 99.5%
SCHEMBL19379
HEXYLENE GLYCOL [MI]
1,3-Trimethyltrimethylenediol
2,4-pentanodiol, 2-metil-
HEXYLENE GLYCOL [HSDB]
HEXYLENE GLYCOL [INCI]
CHEMBL2104293
2- methylpentane- 2, 4- diol
NSC8098
(?)-2-Methyl-2,4-pentanediol
SVTBMSDMJJWYQN-UHFFFAOYSA-N
HMS3264E19
HY-B0903
2 - methylpentane - 2,4 - diol
Hexylene glycol, analytical standard
Tox21_201975
Tox21_302818
(+/-)-2-Methyl-2,4-pentanediol
s3588
AKOS015901459
CCG-213719
WLN: QY1 & 1XQ1 & 1
NCGC00249143-01
NCGC00256494-01
NCGC00259524-01
(+/-)-2,4-Dihydroxy-2-methyl pentane
AC-13749
AS-58339
Hexylene glycol, BioXtra, >=99% (GC)
(+/-)-2-Methyl-2,4-pentanediol, MPD
LS-101663
FT-0605050
FT-0605756
FT-0613069
Hexylene glycol, puriss., >=99.0% (GC)
M0384
(S)-(-)-2-METHYL-2,4-PENTANEDIOL
.alpha.,.alpha.'-Trimethyltrimethylene glycol
alpha,alpha,alpha'-trimethyltrimethyleneglycol
Hexylene glycol, BioUltra, >=99.0% (GC)
D04439
EN300-170052
AB01563179_01
J-640306
J-660006
Q2792203
W-108748
Z1255485267
(±)-2-Methyl-2,4-pentanediol, MPD
2,4-Pentanediol, 2-methyl-
α,α,α'-Trimethyltrimethylene glycol
Diolane
Isol; 1,1,3-Trimethyltrimethylenediol
2-Methyl-2,4-pentandiol
2-Methyl-2,4-pentanediol
2,4-Dihydroxy-2-methylpentane
4-Methyl-2,4-pentanediol
2-Methyl pentane-2,4-diol
2-Methylpentan-2,4-diol
Pinakon
4-Methyl-2,4-pentanediole
(.+/-.)-2-Methyl-2,4-pentanediol
NSC 8098
Isophthalic acid
2-Methylpentan-2,4-diol
Hexylenglykol
2-Methyl-2,4-Pentandiol
1,2-Hexanediol
(2,4-dihydroxy-2-methylpentane
2,4-pentanediol, 2-methyl-
2-methylpentane-2,4-diol
4-methyl-2,4-pentanediol
alpha,alpha,alpha’-trimethyltrimethylene glycol
diolane
hexylene glycol
isol
pinakon
2,4-dihydroxy-2-methylpentane
2-methyl-2,4-pentanediol
4-methyl-2,4-pentanediol
2-methylpentane-2,4-diol
2,4-Pentanediol, 2-methyl-
2-Methyl-2,4-pentanediol
Hexylene glycol
1,1,3-Trimethyltrimethylenediol
2,4-Dihydroxy-2-methylpentane
2,4-Pentanediol, 2-methyl-
2-Methyl pentane-2,4-diol
2-Methyl-2,4-pentanediol
4-Methyl-2,4-pentanediol
Diolane
Isol
Pinakon


HEXYLENE GLYCOL (HG)
Hexylene Glycol (HG) is a colourless liquid organic compound with a characteristic sweet odour.
Hexylene Glycol (HG) is viscous and miscible with the most common organic solvents, fatty acids and water.


CAS Number: 107-41-5
EC Number: 203-489-0
MDL number: MFCD00004547
Chem/IUPAC Name: 2-Methylpentane-2,4-diol
Molecular Formula: C6H14O2 or (CH3)2COHCH2CHOHCH3



2-furanmethanol, 2-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, Hexylene glycol, 2-METHYL-2,4-PENTANEDIOL, 107-41-5, 2-Methylpentane-2,4-diol, Diolane, Pinakon, 2,4-Pentanediol, 2-methyl-, 2,4-Dihydroxy-2-methylpentane, Isol, 4-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, Caswell No. 574, 2-Methyl pentane-2,4-diol, 2-Methyl-2,4-pentandiol, hexyleneglycol, HSDB 1126, UNII-KEH0A3F75J, (+-)-2-Methyl-2,4-pentanediol, NSC 8098, NSC-8098, EINECS 203-489-0, KEH0A3F75J, alpha,alpha,alpha'-Trimethyltrimethylene glycol, EPA Pesticide Chemical Code 068601,
BRN 1098298, 1,3-dimethyl-3-hydroxybutanol, CCRIS 9439, DTXSID5021885, CHEBI:62995, AI3-00919, Hexylene glycol [NF], 1,3,3-trimethyl-1,3-propanediol,
TRACID RUBINE 5BL, DTXCID101885, EC 203-489-0, 1,1,3-trimethyl-1,3-propanediol, 4-01-00-02565 (Beilstein Handbook Reference), Hexylene glycol (NF), 7-MethylAtracuriumDimesylate(MixtureofDiastereomers), MPD, CAS-107-41-5, 2-Methylpentan-2,4-diol, 2-Methyl-pentane-2,4-diol, 64229-01-2, MFCD00004547, Hexylene glycol, 99%, R-(-)-2-METHYL-2,4-PENTANEDIOL, 2methyl-2,4-pentanediol, Hexylene glycol, >=99%, Hexylene glycol, 99.5%, SCHEMBL19379, 1,3-Trimethyltrimethylenediol, CHEMBL2104293, NSC8098, (?)-2-Methyl-2,4-pentanediol, SVTBMSDMJJWYQN-UHFFFAOYSA-N, HMS3264E19, HY-B0903, Hexylene glycol, analytical standard, Tox21_201975, Tox21_302818, s3588, AKOS015901459, CCG-213719, WLN: QY1 & 1XQ1 & 1, NCGC00249143-01, NCGC00256494-01, NCGC00259524-01, AC-13749, AS-58339, Hexylene glycol, BioXtra, >=99% (GC), (+/-)-2-Methyl-2,4-pentanediol, MPD, FT-0605050, FT-0605756, FT-0613069, Hexylene glycol, puriss., >=99.0% (GC), M0384, (S)-(-)-2-METHYL-2,4-PENTANEDIOL, .alpha.,.alpha.'-Trimethyltrimethylene glycol, Hexylene glycol, BioUltra, >=99.0% (GC), D04439, EN300-170052, AB01563179_01, J-640306, J-660006, Q2792203, W-108748, Z1255485267, Hexylene glycol, United States Pharmacopeia (USP) Reference Standard,
Diolane, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, MPD, MVD, FP17780, NSC 66498, Einecs 227-150-, 3-Methylpentanediol-2,4,
2-METHYLPENTANE-2,4-DIOL, 3-METHYL-2,4-PENTANEDIOL, 3-methyl-pentane-2,4-diol, 2,4-Pentanediol, 3-methyl-, HGL, Diolane, Isol, Pinakon, 1,1,3-Trimethyl-Triethylenediol, Diacetone Glycol, Methylamilene Glycol, 2,4-Dihydroxy-2- Methyl-Penthane, 2-Methyl-Penthane-2,4-Diol., (+-)-2-Methyl-2,4-pentanediol, 1,1,3-Trimethyltrimethylenediol, 2,4-Dihydroxy-2-methylpentane, 2,4-Pentanediol, 2-methyl-, 2-Methyl pentane-2,4-diol, 2-Methyl-2,4-pentanediol, 4-Methyl-2,4-pentanediol, Diolane, Hexylene glycol, Isol, Pinakon, alpha,alpha,alpha'-Trimethyltrimethylene glycol, HGL, 1, 1, 3-Trimethyl-Triethylenediol, Diacetone Glycol, Methylamilene Glycol, 2, 4-Dihydroxy-2-Methyl-Penthane, 2-Methyl-Penthane-2, 4-Diol, 2-Hexyl-1,3-dioxolan-2-one, Hexylene Glycol, HG,




Hexylene Glycol (HG) is an oily colorless liquid with a mild sweet odor.
Hexylene Glycol (HG) floats and mixes slowly with water.
Hexylene Glycol (HG) is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).


Hexylene Glycol (HG) is a natural product found in Nicotiana tabacum with data available.
Hexylene Glycol (HG) is a clear, colorless liquid with a characteristic odor.
Hexylene Glycol (HG) is available in Industrial grade and NF grade.


Hexylene Glycol (HG) is a colorless liquid produced industrially from diacetone alcohol by hydrogenation.
Hexylene Glycol (HG) is miscible with water, hydrocarbons, and fatty acids.
Hexylene Glycol (HG) is a colorless transparent liquid.


Hexylene Glycol (HG) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics.
Hexylene Glycol (HG) exhibits antibacterial and antifungal properties.
Hexylene Glycol (HG), as known as 2-Methyl-2,4-pentanediol, is an organic compound, is a colorless liquid, and is a chiral diol.


Hexylene Glycol (HG) is manufactured industrially from diacetone alcohol by hydrogenation.
Hexylene Glycol (HG) is a liquid with a mild, sweet odor.
Hexylene Glycol (HG) is a clear, colorless liquid.


Hexylene Glycol (HG) is a liquid free from colour, containing a typical smell for glycol.
Hexylene Glycol (HG) is a clear, colorless liquid commonly used as a solvent and viscosity-decreasing agent in a wide range of industries including cosmetics, pharmaceuticals, and chemicals.


Hexylene Glycol (HG) is a colourless liquid organic compound with a characteristic sweet odour.
Hexylene Glycol (HG) is viscous and miscible with the most common organic solvents, fatty acids and water.
Hexylene Glycol (HG) is low-evaporating solvent with complete water solubility.


Hexylene Glycol (HG) is miscible with the most common organic solvents, fat acids and water.
Hexylene Glycol (HG) is a versatile clear liquid that finds application in various industries.
Hexylene Glycol (HG) is soluble in most organic solvents and is known for its favorable properties.


Hexylene Glycol (HG) is a colorless liquid with a mild, sweetish odor.
Global Hexylene Glycol (HG) Market is expected to grow at a CAGR of 3.7% during the forecast period and market is projected to reach US$ 1114.9 Mn. by 2027.
Hexylene Glycol (HG) is a clear, colorless liquid.


The market growth of Hexylene Glycol (HG) is driven by the factors such as increasing investment in the research & development, with the growth in the personal care & cosmetic industry, as Hexylene glycol is used as an emulsifier, surfactant, and viscosity reducing agents in the manufacturing of skincare and other cosmetic products there is a high demand for Hexylene glycol.


Other factors that are driving the market growth are increasing demand from the agricultural industry and automotive industry.
In the automotive industry, there is a high demand for Hexylene Glycol (HG) as it is used as a coupling agent in hydraulic fluids.
Hexylene Glycol (HG) can cause irritation to the throat, nose, wheezing, and coughing when it is exposed to air these factors may restrain the market growth.


Rising demand from the paint & coating industry has made a positive impact on the sales Hexylene Glycol (HG) market.
The use of Hexylene Glycol (HG) in hydraulic fluids has created many lucrative opportunities for the key players.



USES and APPLICATIONS of HEXYLENE GLYCOL (HG):
Hexylene Glycol (HG) is low-evaporating solvent with complete water solubility.
Hexylene Glycol (HG) is mainly used as a surfactant or emulsifying agent.
Hexylene Glycol (HG) is widely used in the coating industry as a component for lacquers, varnishes, printing inks and both oil and water-based paints.


Hexylene Glycol (HG) is also as an inert ingredients in pesticide formulations, as a solvent in dyes preparations, as a coupling agent for hydraulic fluids in the automotive industry, as a wetting agent, as an anti-caking agent for cement and siliceous derived industries, as a setting agent in the manufacture of textiles, and as a component in cosmetics, industrial and household cleaners, antifreeze solutions, and intermediate for the synthesis of pharmaceuticals and agrochemicals.


Hexylene Glycol (HG) has many uses including hydraulic brake fluids, printing inks, a coupling agent for textiles, fuels and lubricants, emulsifying agent, cosmetics, and cleaners.
Hexylene Glycol (HG) is used Solvent, Chemical Intermediate, Cosmetics, Paints, Coatings.


Hexylene Glycol (HG) is mostly used as a solvent and viscosity diminishing force in cosmetic items.
Hexylene Glycol (HG) is mainly used for cosmetic uses and paints.
The principal end uses of Hexylene Glycol (HG) include industrial solvent, chemical intermediate, cosmetics, paints and coatings.


Hexylene Glycol (HG) is used in chemical manufacturing, as a solvent, and in hydraulic fluids.
Hexylene Glycol (HG) is a highly versatile compound that is primarily utilized as an ingredient in personal care products such as hair care and skin care formulations, perfumes, and deodorants.


In addition, Hexylene Glycol (HG) is extensively used as a solvent in adhesives, paints, coatings, and inks.
Hexylene Glycol (HG) finds application in various industries.
In the paints and coatings sector, Hexylene Glycol (HG) serves as a solvent and viscosity reducer.


In the chemicals industry, Hexylene Glycol (HG) is used as an intermediate in the synthesis of other chemicals.
In the oil and gas industry, Hexylene Glycol (HG) acts as a solvent for various substances.
In leather and textile manufacturing, Hexylene Glycol (HG) helps in dyeing and finishing processes.


Hexylene Glycol (HG) also finds use in construction, drugs, cosmetics, and personal care products due to its solvency and preservative properties.
Hexylene Glycol (HG) is mainly used as a surfactant or emulsifying agent.
Hexylene Glycol (HG) is widely used in the coating industry as a component for lacquers, varnishes, printing inks and both oil and water-based paints.


Hexylene Glycol (HG) is also used as an inert ingredients in pesticide formulations, as a solvent in dyes preparations, as a coupling agent for hydraulic fluids in the automotive industry, as a wetting agent, as an anti-caking agent for cement and siliceous derived industries, as a setting agent in the manufacture of textiles, and as a component.


Hexylene Glycol (HG) is used in cosmetics, industrial and household cleaners, antifreeze solutions, and intermediate for the synthesis of pharmaceuticals and agrochemicals.
Hexylene Glycol (HG) can be used as a coalescing agent in water-borne formulations for decorative paints, as a coupling agent in water-based coatings for the industrial segment, hydraulic fluids, and industrial cleaning products.


Its humectant function makes Hexylene Glycol (HG) broadly applicable in perfume and cosmetics.
Hexylene Glycol (HG) is also used in formulations for firefighting foams, detergents, degreasers, and other products.
Hexylene Glycol (HG) İS Used as a solvent plasticizer in paints and lacquers; Also used in the chemical, petroleum refining, and cosmetic industries and as an additive to hydraulic fluids, inks, cement, leather, paper, and textiles.


Chemical Manufacturing: Hexylene Glycol (HG) is used as a key ingredient in chemical manufacturing processes.
Coatings and Paints: Hexylene Glycol (HG) serves as a solvent in the formulation of coatings and paints, contributing to their performance and durability.
Personal Care Products: Hexylene Glycol (HG) is used in cosmetics and personal care products due to its excellent solvent properties.


Industrial Cleaning: Hexylene Glycol (HG) is used in industrial cleaning products for its ability to dissolve various substances.
The principal end uses of Hexylene Glycol (HG) include industrial solvent, chemical intermediate, cosmetics, and excipient in pharmaceuticals, paints, and coatings.


Hexylene Glycol (HG) is available in technical grade and NF grade.
In personnel care & cosmetic, an industrial solvent, and antifreeze solutions Hexylene Glycol (HG) is used as a surfactant or emulsifying agent and in coating applications.


Hexylene Glycol (HG) is used as oil and water-based paints, printing inks, lacquers, and varnishes.
Other uses of Hexylene Glycol (HG) are used as a solvent in hydraulic fluids in coupling agents, textile, and cement formulations process pesticides formulations.



FUNCTIONS OF HEXYLENE GLYCOL (HG):
*Emollient (Personal Care)
*Wetting
*Dispersion
*Solvency
*Detergent / Cleaning
*Emollient (Home Care)



HEXYLENE GLYCOL (HG) MARKET ANALYSIS BY TYPES IS SEGMENTED INTO:
*Pharmaceutical Grade:
*Industrial Grade:
Hexylene Glycol (HG) is a chemical compound used in various industries.

In the pharmaceutical grade market, Hexylene Glycol (HG) is utilized in the manufacturing of medications, acting as a carrier and solvent for active ingredients, ensuring their effectiveness.

On the other hand, the industrial grade market uses Hexylene Glycol (HG) for different purposes, such as in the production of paints, coatings, and cosmetics, where it functions as a solvent and helps improve product viscosity and stability.
In both markets, Hexylene Glycol (HG) plays a vital role in enhancing the overall quality and performance of various products.



HEXYLENE GLYCOL (HG) MARKET INDUSTRY RESEARCH BY APPLICATION IS SEGMENTED INTO:
*Paints & Coatings
*Chemicals
*Oil & Gas
*Leather & Textile
*Construction
*Drug, Cosmetics, Personal Care



FUNCTIONS OF HEXYLENE GLYCOL (HG):
Hexylene Glycol (HG) is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.
Hexylene Glycol (HG) is mainly used as a solvent or coupling agent.

Hexylene Glycol (HG) is a potential substitute for glycol ethers.
Hexylene Glycol (HG) is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexylene Glycol (HG) can also be used as a building block in chemical synthesis.



THE FUTURE OUTLOOK FOR THE HEXYLENE GLYCOL (HG) MARKET LOOKS PROMISING:
The market is expected to grow at a significant compound annual growth rate (CAGR) of % during the forecasted period.
This growth can be attributed to several factors such as the increasing demand for personal care products, particularly in emerging economies, the rising trend of urbanization, and the growing awareness regarding personal grooming and hygiene.

Furthermore, the expanding application scope of Hexylene Glycol (HG) in various industries such as paints and coatings, pharmaceuticals, and textiles is also contributing to the market growth.
Hexylene Glycol (HG)’s unique properties, including excellent solvency, low volatility, and ability to dissolve a wide range of materials, make it an attractive choice for various industrial applications.

Another factor driving the market growth is the continuous advancements in the manufacturing processes of Hexylene Glycol (HG), leading to improved product quality and cost-effectiveness.
Research and development activities within the industry are focusing on the development of eco-friendly and sustainable production methods, which will further boost the market growth.

In summary, the Hexylene Glycol (HG) market is projected to experience substantial growth in the coming years, driven by factors such as the increasing demand for personal care products, expanding application scope, and advancements in manufacturing processes.
The market of Hexylene Glycol (HG) is anticipated to witness a CAGR of % during the forecasted period.



WHAT ARE THE EMERGING TRENDS IN THE GLOBAL HEXYLENE GLYCOL (HG) MARKET?
The global Hexylene Glycol (HG) market is witnessing several emerging trends.
Firstly, there is increasing demand for Hexylene Glycol (HG) in personal care and cosmetics industries as it acts as a solvent and viscosity agent in various products.

Secondly, the growing popularity of sustainable and bio-based products is encouraging the development of environmentally friendly alternatives to Hexylene Glycol (HG).

Additionally, the automotive industry is also creating demand for Hexylene Glycol (HG) due to its use as a coolant and antifreeze agent.
Lastly, there is a rising focus on emerging economies, like China and India, due to their growing industrial sectors and demand for HG in various applications.



PHYSICAL and CHEMICAL PROPERTIES of HEXYLENE GLYCOL (HG):
Molecular Weight: 118.17
XLogP3-AA: 0.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 118.099379685
Monoisotopic Mass: 118.099379685
Topological Polar Surface Area: 40.5 Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 68.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical name (CAS): 2-methyl-2,4-pentanediol
CAS number: 107-41-5
Structural formula: CH3–CH(OH)–CH2–C(OH)(CH3)2
Molecular formula: C6H14O2
Molecular weight: 118.18
Melting point: –40°C
Boiling point: 195–200°C
Density at 20°C: 0.920–0.923 g/cm3
Vapour pressure at: 20°C 0.06 hPa
log Pow*: –0.14

CAS number: 107-41-5
EC index number: 603-053-00-3
EC number: 203-489-0
Grade: NF
Hill Formula: C₆H₁₄O₂
Molar Mass: 118.18 g/mol
HS Code: 2926 90 70
Density: 0.922 g/cm3 (20 °C)
Explosion limit: 1 - 9.9 %(V)
Flash point: 94 °C
Ignition temperature: 425 °C
Melting Point: -40 °C
pH value: 6.0 - 8.0 (118.2 g/l, H₂O, 25 °C)

Vapor pressure: 0.03 hPa (20 °C)
Physical state: liquid
Color: colorless
Odor: sweet, mild
Melting point/freezing point:
Melting point/range: -40 °C - lit.
Initial boiling point and boiling range: 197 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 7,4 %(V)
Lower explosion limit: 1,3 %(V)
Flash point: 94 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 6,0 - 8,0 at 118,2 g/l at 25 °C

Solubility:
Easily soluble in cold water.
Soluble in diethyl ether.
Soluble in alcohol, lower aliphatic hydrocarbons.
Soluble in a variety of organic solvents.
Miscible with fatty acids
Specific Gravity 20/20 °C:0.9232
Distillation Range at 760 mm Hg (IP) °C:196.4
Distillation Range at 760 mm Hg (DP) °C:198.2
Purity, % w/w:99.62
Acidity as acetic Acid, % w/w: 0.0010
Water, % w/w: 0.018
Melting point: −40 °C(lit.)
Boiling point: 197 °C(lit.)
Density: 0.925 g/mL at 25 °C(lit.)
vapor density: 4.1 (vs air)
vapor pressure: 0.02 mm Hg ( 20 °C)
refractive index: n20/D 1.427(lit.)

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 36 mPa.s at 20 °C
Water solubility ca.: 118,2 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,58 - (Lit.), Bioaccumulation is not expected.
Vapor pressure: 0,03 hPa at 20 °C
Density: 0,925 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available

Explosive properties: No data available
Oxidizing properties: none
Other safety information
Relative vapor density: 4,08 - (Air = 1.0)
Molar Weight: 118.176g/mol
Melting Point: -40 °C
Boiling Point: 196 °C
Flash Point: 93 °C
Density: 0.925
Forms: Liquid (clear)

Chemical formula: C6H14O2
Molar mass: 118.176 g·mol−1
Appearance: colourless liquid
Odor: mild, sweetish
Density: 0.92 g/mL
Melting point: −40 °C (−40 °F; 233 K)
Boiling point: 197 °C (387 °F; 470 K)
Solubility in water: miscible[1]
Vapor pressure: 0.05 mmHg (20°C)
Flash point: 98.3 °C (208.9 °F; 371.4 K)
Explosive limits: 1.3%-7.4%
Appearance: colorless clear liquid (est)

Physical state and Appearance:Liquid.
Odor:Sweetish
Molecular Weight:118.18 g/mole
Color:Colorless
Boiling Point:197 (386.6) - 198° C
Melting Point:-50 - (-58)
Specific Gravity:0.9254 @ 17 C; 0.9234 @ 20 C (Water = 1)
Vapor Pressure: 0.05 mm of Hg (@ 20)
Vapor Density: 4.1 (Air = 1)
Odor Threshold: 50 ppm
Dispersion Properties: See solubility in water, diethyl ether
Flash point: 201 °F
storage temp.: 2-8°C
solubility: H2O: 1 M at 20 °C, clear, colorless
pka: 14.72±0.20(Predicted)
CAS DataBase Reference: 5683-44-3(CAS DataBase Reference)

Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92400 @ 25.00 °C.
Melting Point: -40.00 °C. @ 760.00 mm Hg
Boiling Point: 197.00 to 199.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.096000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.1 ( Air = 1 )
Flash Point: > 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w): 0.004 (est)
Soluble in: alcohol
water, 3.256e+004 mg/L @ 25 °C (est)
water, 1.00E+06 mg/L @ 25 °C (exp)

Molecular Weight: 118.2 g/mol
Empirical Formula: C6H14O2
Appearance: Colorless, Liquid
Freezing Point: -50°C (-58.0°F)
Boiling Point: @ 760mm Hg 196°C (385°F)
Flash Point: Closed Cup 96°C (205°F)
Autoignition Temperature: 425°C (797°F)
Density @ 20°C: 0.924 kg/L, 7.71 lb/gal
Vapor Pressure: @ 20°C 0.05 mmHg
Evaporation Rate: (nBuAc = 1) 0.007
Solubility in Water: @ 20°C Miscible

Surface Tension @ 20°C: 33.1 dynes/cm
Refractive Index @ 20°C: 1.426
Viscosity @ 20°C: 38.9 cP
Lower Explosive Limit: 1.0 v/v%
Upper Explosive Limit: 9.9 v/v%
Conductivity @ 20°C: 3x106 pS/m
Dielectric Constant @ 20°C: ≈7.7
Specific Heat @ 20°C: 2.20 kJ/kg/°C
Heat of Vaporization @ normal boiling point: 435 kJ/kg
Heat of Combustion @ 25°C: 29875 kJ/kg
Odor Threshold: 50 ppm



FIRST AID MEASURES of HEXYLENE GLYCOL (HG):
-Description of first-aid measures:
*General advice
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HEXYLENE GLYCOL (HG):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HEXYLENE GLYCOL (HG):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HEXYLENE GLYCOL (HG):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 240 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HEXYLENE GLYCOL (HG):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Store under inert gas.
Hygroscopic.



STABILITY and REACTIVITY of HEXYLENE GLYCOL (HG):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available

HEXYLENE GLYCOL (HG)
DESCRIPTION:
Hexylene Glycol (HG) is a clear, colorless liquid with a characteristic odor.
Hexylene Glycol (HG) is Available in Industrial grade and NF grade.
Hexylene Glycol or HG is an oxygenated solvent derived from acetone which has two alcohol functions

CAS: 107-41-5
European Community (EC) Number: 203-489-0
IUPAC Name: 2-methylpentane-2,4-diol
Molecular Formula: C6H14O2

SYNONYMS OF HEXYLENE GLYCOL (HG)

2-methyl-2,4-pentanediol,2-methylpentane-2,4-diol,hexylene glycol,hexylene glycol, titanium(4+) salt,Hexylene glycol,2-METHYL-2,4-PENTANEDIOL,107-41-5,2-Methylpentane-2,4-diol,Diolane,Pinakon,2,4-Pentanediol, 2-methyl-,2,4-Dihydroxy-2-methylpentane,4-Methyl-2,4-pentanediol,1,1,3-Trimethyltrimethylenediol,Caswell No. 574,2-Methyl pentane-2,4-diol,2-Methyl-2,4-pentandiol,hexyleneglycol,HSDB 1126,TRACID RUBINE 5BL,UNII-KEH0A3F75J,(+-)-2-Methyl-2,4-pentanediol,NSC 8098,NSC-8098,EINECS 203-489-0,KEH0A3F75J,alpha,alpha,alpha'-Trimethyltrimethylene glycol,EPA Pesticide Chemical Code 068601,BRN 1098298,1,3-dimethyl-3-hydroxybutanol,CCRIS 9439,DTXSID5021885,CHEBI:62995,AI3-00919,Hexylene glycol [NF],1,3,3-trimethyl-1,3-propanediol,DTXCID101885,EC 203-489-0,1,1,3-trimethyl-1,3-propanediol,4-01-00-02565 (Beilstein Handbook Reference),Hexylene glycol (NF),HEXYLENE GLYCOL (II),HEXYLENE GLYCOL [II],7-MethylAtracuriumDimesylate(MixtureofDiastereomers),MPD,HEXYLENE GLYCOL (MART.),HEXYLENE GLYCOL [MART.],HEXYLENE GLYCOL (USP-RS),HEXYLENE GLYCOL [USP-RS],64229-01-2,CAS-107-41-5,2-Methylpentan-2,4-diol,2-Methyl-pentane-2,4-diol,MFCD00004547,Hexylene glycol, 99%,R-(-)-2-METHYL-2,4-PENTANEDIOL,2methyl-2,4-pentanediol,Hexylene glycol, >=99%,Hexylene glycol, 99.5%,SCHEMBL19379,HEXYLENE GLYCOL [MI],1,3-Trimethyltrimethylenediol,HEXYLENE GLYCOL [HSDB],HEXYLENE GLYCOL [INCI],CHEMBL2104293,NSC8098,(?)-2-Methyl-2,4-pentanediol,SVTBMSDMJJWYQN-UHFFFAOYSA-N,HMS3264E19,HY-B0903,Hexylene glycol, analytical standard,Tox21_201975,Tox21_302818,s3588,AKOS015901459,CCG-213719,WLN: QY1 & 1XQ1 & 1,NCGC00249143-01,NCGC00256494-01,NCGC00259524-01,AC-13749,AS-58339,Hexylene glycol, BioXtra, >=99% (GC),(+/-)-2-Methyl-2,4-pentanediol, MPD,FT-0605050,FT-0605756,FT-0613069,Hexylene glycol, puriss., >=99.0% (GC),M0384,NS00005763,(S)-(-)-2-METHYL-2,4-PENTANEDIOL,alpha.,.alpha.'-Trimethyltrimethylene glycol,Hexylene glycol, BioUltra, >=99.0% (GC),D04439,EN300-170052,AB01563179_01,J-640306,J-660006,Q2792203,W-108748,Z1255485267,Hexylene glycol, United States Pharmacopeia (USP) Reference Standard
Hexylene glycol is an oily colorless liquid with a mild sweet odor.
Hexylene Glycol (HG) Floats and mixes slowly with water.

2-methylpentane-2,4-diol is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).
Hexylene glycol is a natural product found in Nicotiana tabacum with data available.

Hexylene Glycol (HG) is a clear, colorless liquid.
The principal end uses of HG include industrial solvent, chemical intermediate, cosmetics, excipient in pharmaceuticals, paints and coatings.
Hexylene Glycol (HG) is Available in technical grade and NF grade


Hexylene Glycol is a colourless liquid organic compound with a characteristic sweet odour.
Hexylene Glycol (HG) is viscous and miscible with the most common organic solvents, fatty acids and water.

Hexylene glycol (HG) is a colorless liquid produced industrially from diacetone alcohol by hydrogenation.
Hexylene Glycol (HG) is miscible with water, hydrocarbons, and fatty acids.
Hexylene glycol has many uses including hydraulic brake fluids, printing inks, a coupling agent for textiles, fuels and lubricants, emulsifying agent, cosmetics, and cleaners.

Hexylene Glycol, as known as 2-Methyl-2,4-pentanediol, is an organic compound, is a colorless liquid, and is a chiral diol.
Hexylene Glycol (HG) is manufactured industrially from diacetone alcohol by hydrogenation.

Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) is an oxygenated solvent derived from acetone that has been used widely in industrial chemicals and cosmetics.
Hexylene glycol exhibits antibacterial and antifungal properties.

Hexylene Glycol (Novaguard HG) acts as a skin-conditioning agent, the emollient features of Hexiol bring a soft and pleasant feel to your formulations.
Hexylene Glycol (HG) also functions as a skin humectant with long lasting effect.
Hexylene Glycol (HG) has bacteriostatic and bactericidal properties which are useful in cosmetics as a preservative.
Hexylene Glycol (HG) is an exact alternative to Dermosoft Hexiol, Hydrolite 6, Lexgard H and Optiphen HD.

Hexylene Glycol (Novaguard HG) a high purity 1,2-Hexanediol that can be used in personal care formulations not only as a humectant, but also as a safe substitute of traditional preservatives.
Hexylene Glycol (HG) has a broad anti-microbial ability with limited endocrine disrupting effect.

Manufacturing of Novaguard HG involves processes of reducing the undesirable odor of 1,2-Hexanediol and bringing the purity up to min 99.0%.
Hexylene Glycol (HG) acts as a humectant, preservative and moisturizing giver.

In addition, Hexylene Glycol (HG) can be used either alone or in combination with other preservatives to combat microorganisms directly and thus reduce or eliminate body odor, acne or mycoses.
Hexylene Glycol (HG) is applicable in skin care products, deodorants and moisturizing formulations


FUNCTIONS OF HEXYLENE GLYCOL (HG):
Hexylene glycol is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.
Hexylene Glycol (HG) is mainly used as a solvent or coupling agent.
Hexylene Glycol (HG) is a potential substitute for glycol ethers.

Hexylene Glycol (HG) is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexylene glycol can also be used as a building block in chemical synthesis.


USES OF HEXYLENE GLYCOL (HG):
Hexylene Glycol or HG is an oxygenated solvent derived from acetone which has two alcohol functions.
Hexylene Glycol (HG) has a low evaporation rate and it is completely miscible with water.

Hexylene Glycol (HG) is mainly used as a solvent or coupling agent.
Hexylene Glycol (HG) is a potential substitute for glycol ethers.

Hexylene Glycol (HG) is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexylene glycol can also be used as a building block in chemical synthesis.
Hexylene glycol is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.


Hexylene Glycol is low-evaporating solvent with complete water solubility.
Hexylene Glycol (HG) is mainly used as a surfactant or emulsifying agent.
Hexylene Glycol is widely used in the coating industry as a component for lacquers, varnishes, printing inks and both oil and water-based paints.

Hexylene Glycol (HG) is also as an inert ingredients in pesticide formulations, as a solvent in dyes preparations, as a coupling agent for hydraulic fluids in the automotive industry, as a wetting agent, as an anti-caking agent for cement and siliceous derived industries, as a setting agent in the manufacture of textiles, and as a component in cosmetics, industrial and household cleaners, antifreeze solutions, and intermediate for the synthesis of pharmaceuticals and agrochemicals.



FEATURES OF HEXYLENE GLYCOL (HG):
Hexylene Glycol (HG) is Skin humectant
Hexylene Glycol (HG) is Emollient
Hexylene Glycol (HG) is Globally Approved

Hexylene Glycol (HG) Antimicrobial protection agent and preservation booster
Hexylene Glycol (HG) is Effective at a wide pH rangeAlternative to conventional preservatives



CHEMICAL AND PHYSICAL PROPERTIES OF HEXYLENE GLYCOL (HG)
Purity (% by weight) : ≥ 99,5
Appearance at 20°C : clear liquid free from suspended materials
Density at 20°C (g/cm3) : 0,920 - 0,923
Boiling point at 1013 Pa : 197,5°C
Flash point (closed cup) : 97°C
Water solubility at 20°c : complete
Hansen Solubility Parameters at 25°C: δt = 25,2; δd = 15,8; δp = 8,4; δh = 17
Molecular Weight
118.17 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3-AA
0.3
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
118.099379685 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
118.099379685 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
40.5Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
8
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
68.9
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
1
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
Molecular Weight 118.2 g/mol
Empirical Formula C6H14O2
Appearance Colorless Liquid
Freezing Point -50°C (-58.0°F)
Boiling Point @ 760mm Hg 196°C (385°F)
Flash Point – Closed Cup 96°C (205°F)
Autoignition Temperature 425°C (797°F)
Density @ 20°C 0.924 kg/L 7.71 lb/gal
Vapor Pressure @ 20°C 0.05 mmHg
Evaporation Rate (nBuAc = 1) 0.007
Solubility in Water @ 20°C
Miscible Surface Tension @ 20°C 33.1 dynes/cm
Refractive Index @ 20°C 1.426
Viscosity @ 20°C 38.9 cP
Lower Explosive Limit 1.0 v/v%
Upper Explosive Limit 9.9 v/v%
Conductivity @ 20°C 3x106 pS/m
Dielectric Constant @ 20°C ≈7.7
Specific Heat @ 20°C 2.20 kJ/kg/°C
Heat of Vaporization @ normal boiling point 435 kJ/kg
Heat of Combustion @ 25°C 29875 kJ/kg
Odor Threshold 50 ppm
Appearance Clear colourless liquid
Odour Mild to adourless
Density 0.950 g/ml
Purity 99.00% Minimum
Moisture Content 1.0% Maximum
Solubility. Soluble in Alcohol
Origin: Synthetic
Shelf life: 1 year from mfg. date
Freight Classification: NMFC48580 S3 CL55
Kosher Status: Not Kosher
Flash Point: 93øC Closed Cup
Melting Point: -50øC
API: NO
Allergen: NO
Hazmat: YES
Molecular Weight: 118.18 g/mol



SAFETY INFORMATION ABOUT HEXYLENE GLYCOL (HG):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.




HEXYLENE GLYCOL (HG)
Hexylene Glycol (HG) is an oxygenated solvent derived from acetone which has two alcohol functions.
Hexylene Glycol (HG) has a low evaporation rate and it is completely miscible with water.
Hexylene Glycol (HG) is mainly used as a solvent or coupling agent.

CAS: 107-41-5
MF: C6H14O2
MW: 118.17
EINECS: 203-489-0

Synonyms
2-METHYL-2,4-PENTANEDIOL, 99%2-METHYL-2,4-PENTANEDIOL, 99%2-METHYL-2,4-PENTANEDIOL, 99%;2,4-Dihydroxy-2-Methyl-Penthane;MPD;2-METHYLPENTAN-2,4-DIOL;2-METHYLPENTANE-2,4-DIOL;2-Methyl-2,4-pentadiol;(+/-)-2-METHYL-2,4-PENTANEDIOL;2-METHYL-2,4-PENTANEDIO;Hexylene glycol;2-METHYL-2,4-PENTANEDIOL;107-41-5;2-Methylpentane-2,4-diol;Diolane;Pinakon;2,4-Pentanediol, 2-methyl-
;2,4-Dihydroxy-2-methylpentane;Isol;4-Methyl-2,4-pentanediol;1,1,3-Trimethyltrimethylenediol;Caswell No. 574;2-Methyl pentane-2,4-diol;2-Methyl-2,4-pentandiol;hexyleneglycol;HSDB 1126;TRACID RUBINE 5BL;UNII-KEH0A3F75J;(+-)-2-Methyl-2,4-pentanediol;NSC 8098;NSC-8098;EINECS 203-489-0;KEH0A3F75J;alpha,alpha,alpha'-Trimethyltrimethylene glycol;EPA Pesticide Chemical Code 068601;BRN 1098298
;1,3-dimethyl-3-hydroxybutanol;CCRIS 9439;DTXSID5021885;CHEBI:62995;AI3-00919;Hexylene glycol [NF];1,3,3-trimethyl-1,3-propanediol;DTXCID101885;EC 203-489-0
;1,1,3-trimethyl-1,3-propanediol;4-01-00-02565 (Beilstein Handbook Reference);Hexylene glycol (NF);HEXYLENE GLYCOL (II);HEXYLENE GLYCOL [II];7-MethylAtracuriumDimesylat(MixtureofDiastereomers);MPD;HEXYLENE GLYCOL (MART.);HEXYLENE GLYCOL [MART.];HEXYLENE GLYCOL (USP-RS);HEXYLENE GLYCOL [USP-RS];64229-01-2;CAS-107-41-5;2-Methylpentan-2,4-diol
;2-Methyl-pentane-2,4-diol;MFCD00004547;Hexylene glycol, 99%;R-(-)-2-METHYL-2,4-PENTANEDIOL;2methyl-2,4-pentanediol;Hexylene glycol, >=99%;Hexylene glycol, 99.5%;SCHEMBL19379;HEXYLENE GLYCOL [MI];1,3-Trimethyltrimethylenediol;HEXYLENE GLYCOL [HSDB];HEXYLENE GLYCOL [INCI];CHEMBL2104293;NSC8098;(?)-2-Methyl-2,4-pentanediol;HMS3264E19;HY-B0903;Hexylene glycol, analytical standart;Tox21_201975;Tox21_302818
;s3588;AKOS015901459;CCG-213719;WLN: QY1 & 1XQ1 & 1;NCGC00249143-01;NCGC00256494-01;NCGC00259524-01;AC-13749;AS-58339;Hexylene glycol, BioXtra, >=99% (GC);(+/-)-2-Methyl-2,4-pentanediol, MPD;Hexylene glycol, puriss., >=99.0% (GC);M0384;NS00005763;(S)-(-)-2-METHYL-2,4-PENTANEDIOL;.alpha.,.alpha.'-Trimethyltrimethylene glycol;Hexylene glycol, BioUltra, >=99.0% (GC);D04439;EN300-170052;AB01563179_01;J-640306;J-660006;Q2792203;W-108748;Z1255485267
;Hexylene glycol, United States Pharmacopeia (USP) Reference Standard

Hexylene Glycol (HG) is a potential substitute for glycol ethers.
Hexylene Glycol (HG) is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexylene Glycol (HG) can also be used as a building block in chemical synthesis.
Hexylene Glycol (HG) is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.
Hexylene Glycol (HG) is a diol organic compound with a chiral carbon atom.
Hexylene Glycol (HG) is a colorless liquid at room temperature and can be Diacetone alcohol is hydrogenated.
The appearance is colorless liquid with mild sweetness.

Hexylene Glycol (HG) is miscible with water, soluble in ethanol, and soluble in most organic solvents.
Hexylene Glycol (HG) is a colorless liquid with amild, sweet odor.
The odor threshold is 50 ppm.
Molecularweight= 1 18.20; Specific gravity (H20:1) = 0.92; Boilingpoint = 197.8℃; FreezingMelting point= - 50℃ (sets toglass); Vapor pressure = 0.05 mmHg at 20℃;Flashpoint = 98.3℃; Autoignition temperature = 260℃; 306℃.Explosive limits: LEL= 1.3%; UEL=7.4%.
HazardIdentification (basedon NFPA-704 M Rating System):Health 2, Flammability 1, Reactivity 0. Soluble in water.
A glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).

Hexylene Glycol (HG) is an organic compound with the formula (CH3)2C(OH)CH2CH(OH)CH3.
This colourless liquid is a chiral diol.
Hexylene Glycol (HG) is produced industrially from diacetone alcohol by hydrogenation.
Total European and USA production was 15000 tonnes in 2000.
Hexylene Glycol (HG) exists as two enantiomers, (4R)-(−) and (4S)-(+).
In the Protein Data Bank, the 3-letter code "MPD" refers to the (S)-(−) enantiomer, while "MRD" is used to refer to the (R)-(+) version.
Commercial products labeled "MPD" are usually the racemate, also sold as and referred to as "hexylene glycol".

Hexylene Glycol (HG) Chemical Properties
Melting point: -40 °C (lit.)
Boiling point: 197 °C (lit.)
Density: 0.925 g/mL at 25 °C (lit.)
Vapor density: 4.1 (vs air)
Vapor pressure: 0.02 mm Hg ( 20 °C)
Refractive index: n20/D 1.427(lit.)
Fp: 201 °F
Storage temp.: Store below +30°C.
Solubility H2O: 1 M at 20 °C, clear, colorless
Form: Slightly Viscous Liquid
pka: 15.10±0.29(Predicted)
Color: Clear
PH: 6-8 (25℃, 1M in H2O)
Odor: Ammonia-like.
Explosive limit: 1-9.9%(V)
Water Solubility: soluble
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 14,4710
BRN: 1098298
Dielectric constant: 24.399999999999999
Exposure limits ACGIH: TWA 25 ppm; STEL 50 ppm(10 mg/m3)
NIOSH: Ceiling 25 ppm(125 mg/m3)
Stability: Stable. Incompatible with strong oxidizing agents, strong acids, strong reducing agents.
InChIKey: SVTBMSDMJJWYQN-UHFFFAOYSA-N
LogP: 0 at 20℃
CAS DataBase Reference: 107-41-5(CAS DataBase Reference)
NIST Chemistry Reference: Hexylene Glycol (HG) (107-41-5)
EPA Substance Registry System: Hexylene Glycol (HG) (107-41-5)

Hexylene Glycol (HG) is an oily colorless liquid with a mild sweet odor.
Hexylene Glycol (HG) is an oxygenated solvent derived from acetone which has two alcohol functions.
Hexylene Glycol (HG) has a low evaporation rate and it is completely miscible with water.

Uses
Hexylene Glycol (HG) is a fine chemical product with a wide range of uses, which can be used in pesticides, biochemical engineering, photosensitive materials, synthetic fragrances and other fields.
Hexylene Glycol (HG) is a highly soluble high-grade organic solvent.
Hexylene Glycol (HG) can be used as an additive in the production of metal surface treatment agents for rust and oil removal.
Hexylene Glycol (HG) can also be used as a textile auxiliaries, as well as coatings and latex paints.
Hexylene Glycol (HG) can also be used in cosmetics, as a pesticide stabilizer, but also as a daily chemical moisturizer, flavor and fragrance raw materials, hydraulic oil, high-temperature lubricating oil, brake oil, dry cleaning agent, printing ink, pigment dispersant, wood preservative etc.
As penetrant, emulsifier and antifreeze.

Fuel and lubricant additive; solvent in cosmetics; solvent in petroleum refining; coupling agent in hydraulic brake fluid and printing inks; gasoline anti-icer additive
Hexylene Glycol (HG) is used to control the flow properties of industrial products such as paints, coatings, cleansers, solvents, and hydraulic fluids.
Hexylene Glycol (HG) acts as a thickening agent in cosmetic products.
Hexylene Glycol (HG) serves as a coupling agent and an additive to hydraulic fluids, inks and cement.
Hexylene Glycol (HG) is also employed as a blood volume expander.
Further, Hexylene Glycol (HG) is used as a solvent for cleaning and colorant products.
In addition to this, Hexylene Glycol (HG) is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.

Hexylene Glycol (HG) is used as a reagent in the synthesis of functionalized boronic esters.
Hexylene Glycol (HG) is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.
Also used in the preparation of vinylboronates.
Hexylene Glycol (HG) is mainly used as a coupling agent and an additive to hydraulic fluids, inks and cement.
Further, Hexylene Glycol (HG) is used as a solvent for cleaning and colorant products.
Hexylene Glycol (HG) is a potential substitute for glycol ethers.
Hexylene Glycol (HG) is an effective shrinkage reduction admixture or SRA for concrete and mortar.
Hexylene Glycol (HG) can also be used as a building block in chemical synthesis.
Hexylene Glycol (HG) is a key solvent in many markets such as paints & coatings, metal working fluids, detergency, cosmetics & fragrances, textiles & leather.
Hexylene Glycol (HG) is used to control the flow properties of industrial products such as paints, coatings, cleansers, solvents, and hydraulic fluids.
Hexylene Glycol (HG) acts as a thickening agent in cosmetic products.
Hexylene Glycol (HG) is also employed as a blood volume expander.

Hexylene Glycol (HG) exhibits both surfactant and emulsion-stabilizing properties.
Hexylene Glycol (HG)'s relatively high viscosity and low volatility are advantageous in coatings, cleansers, cosmetics, solvents, lubricants, and hydraulic fluids.
Although Hexylene Glycol (HG) is an irritant at higher concentrations, it is sometimes used in skin care, hair care, soap, and eye cosmetic products at concentrations ranging from 0.1% - 25%.
Hexylene Glycol (HG) is biodegradable and unlikely to accumulate in the environment.

Laboratory uses
In the laboratory Hexylene Glycol (HG) is a common precipitant and cryoprotectant in protein crystallography.
Since Hexylene Glycol (HG) is compatible with polar and nonpolar molecules, it competes with the solvent in a crystallography experiment causing the protein to precipitate.
Hexylene Glycol (HG) is so effective in protein crystallography because its amphiphilic nature and small, flexible structure allows it to bind to many different locations on a protein secondary structure including alpha helices and beta sheets.
When Hexylene Glycol (HG) binds to these different locations, water is removed and the protein crystals anneal, which prevents ice formation during cryocrystallography techniques.
Incorporation of Hexylene Glycol (HG) into solution has been known to improve the resolution of X-ray diffraction making protein structures easily identifiable.
Additionally Hexylene Glycol (HG) is not a strong denaturing agent and thus does not significantly alter the structure of a protein during the crystallography procedure.
Hexylene Glycol (HG) is also used as a lubricant for polishing specimens in metallography.
Like related diols, Hexylene Glycol (HG) forms borate esters.

Preparation
Using 2000 L of diacetone alcohol as a raw material to synthesize isohexanediol by hydrogenation reduction, the specific process steps are:

Step 1: Start the vacuum pump to vacuum the raw material metering tank.
When the vacuum is greater than -0.06Mpa, close the exhaust valve, open the feed valve, mix 2000 L of diacetone alcohol raw material and 200ppm sodium bicarbonate and pump Hexylene Glycol (HG) in Raw material metering tank.

Step 2: Open the vacuum valve on the reduction pot and pump the reduction pot to a vacuum of -0.1Mpa, then open the feed valve on the reduction pot, and add 2000 L of diacetone alcohol raw material and 200ppm sodium bicarbonate from the metering tank To the reduction pot, start the mixer to stir at the same time, add 95Kg of Raney nickel catalyst.

Step 3: Close the vacuum valve, open the nitrogen inlet valve, and inject nitrogen into the reduction pot.
After the pressure in the pot is increased to 0.6Mpa within 3 to 5 minutes, close the hydrogen inlet valve, open the vent valve, and reduce the pressure in the pot.
Reduce to normal pressure, repeat the above steps, re-inject nitrogen for replacement, and repeat this five times.

Step 4: When the nitrogen replacement in the third step is completed, close the vent valve, open the hydrogen inlet valve, and inject hydrogen into the reduction pot within 10-15 minutes. When the pressure in the pot reaches 0.6Mpa, close the hydrogen inlet valve.
Open the vent valve, after the pressure in the pot drops to normal pressure, close the vent valve, repeat the above steps, re-inject hydrogen for replacement, and repeat this five times.

Step 5: After the hydrogen replacement, close the vent valve, open the hydrogen gas inlet valve, and inject hydrogen into the reduction pot.
Use hydrogen to make the pressure in the pot reach 1.9Mpa within 15 to 30 minutes, then close the hydrogen gas inlet valve and open it.
Jacketed steam valve, raise the temperature in the pot to 150°C, and adjust the stirring speed to 310r/min.
At this time, open the hydrogen gas inlet valve and control the temperature in the pot at 150°C.
On the basis of the stable temperature in the pot, Keep the hydrogen vapor pressure at 1.9Mpa for 4 hours, then close the hydrogen gas inlet valve and accurately record the current pressure in the boiler.
After 30 minutes, take a sample for gas chromatographic testing.
If the raw material content is less than 1% in the test result, it is qualified.
At this time, Close the jacketed steam valve and open the jacketed cooling water to reduce the temperature in the pot to normal temperature.
Then, open the vent valve to reduce the pressure in the pot to normal pressure.

Step 6: Stop the mixer and let Hexylene Glycol (HG) stand for 50 minutes, close the vent valve, open the nitrogen inlet valve, use nitrogen to increase the pressure in the pot to 0.6Mpa, close the nitrogen valve, open the empty valve, and slowly reduce the pressure in the pot to normal pressure , And then repeat this step 5 times.

Step 7: Open the nitrogen valve and the feed valve of the distillation pot at the same time.
Use 0.8Mpa nitrogen to send the qualified materials to the filter for filtration.
The filtered materials are pumped into the crude isohexanediol storage tank, and then pressed to the distillation Distillation is carried out in the kettle, and the filtered catalyst is recycled; the finished product from the rectification is isohexanediol.
After the raw material of 2000 L diacetone alcohol is hydrogenated and reduced to synthesize, 1865Kg of isohexanediol product is obtained with a purity of 99.5%.
The mass yield is 99%.
After cooling, Hexylene Glycol (HG) is placed in the isohexanediol product storage tank.
The remaining by-products are mainly 29kg of 98% acetone, which can be sold as industrial acetone.

Production Methods
Hexylene Glycol (HG) is prepared commercially by the catalytic hydrogenation of diacetone alcohol.
Hexylene Glycol (HG) is used as a chemical intermediate, a selective solvent in petroleum refining, a component of hydraulic fluids, a solvent for inks, and as an additive for cement.
Industrial exposure is likely to be from direct contact or from inhalation, particularly if the material is heated.

Chemical Reactivity
Reactivity with Water No reaction; Reactivity with Common Materials: Can catch fire when in contact with porous materials such as wood, asbestos, cloth, soil, or rusty metals; Stability During Transport: Stable at ordinary temperatures, however when heated this material can decompose to nitrogen and ammonia gases.
The decomposition is not generally hazardous unless Hexylene Glycol (HG) occurs in confined spaces; Neutralizing Agents for Acids and Caustics: Flush with water and neutralize the resulting solution with calcium hypochlorite; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
HFZA (HEXAFLUOROZIRCONIC ACID)
HFZA (Hexafluorozirconic acid) is an inorganic compound that exists in two forms: a solid and a liquid.
HFZA (Hexafluorozirconic acid), with the chemical formula F6HZr-, has the CAS number 12021-95-3.


CAS Number: 12021-95-3
EC nUMBER: 234-666-0
MDL Number: MFCD00082965
Molecular Formula: F6HZr-



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fluorozirconic, Zirconate(2-),hexafluoro-,dihydrogen, Dihydrogen hexafluorozirconate solution, Hexafluorozirconic acid solution, dihydrogen hexafluorozirconate(2-), Fluorozirconic acid(H2ZrF6), Fluorozirconate acid, HEXAFLUOROZIRCONIC ACID 45 WT. % SOLUT&, HEXAFLUOROZIRCONIC ACID, 50 WT. % SOLUT&, Zirconate(2-), hexafluoro-, dihydrogen, (OC-6-11)-, Hexafluorozirconic acid 98%, Hexafluorozirconicacid98%, HEXAFLUOROZIRCONIC ACID: 45% IN WATER,
Dihydrogen hexafluorozirconate, 20% w/w aq. soln., Dihydrogen hexafluorozirconate, 45% w/w aq. soln., Dihydrogen hexafluorozirconate, 20% in 2% hydrofluoric acid, 99.9% (metals basis), hydrogen hexafluorozirconate, zirconate(2-),hexafluoro-, hydrogen (1:2), (oc-6-11)-, dihydrogen hexafluorozirconate(2-), fluorozirconic acid(h2zrf6), hexafluorozirconicacid98%, hexafluorozirconic acid 98%, hydrogen zirconiumfluoride (h2zrf6), hydrogen hexafluorozirconate(iv) (7ci), fluorozirconic acid, zirconate(2-), hexafluoro-, dihydrogen,(oc-6-11)- (9ci), hydrogen zirconium fluoride, fluorozirconate acid, zirconate(2-),hexafluoro-, dihydrogen (8ci), fluorozirconic, hexafluorozirconic a, hexafluorozirconic acid, fluozirconic(iv)acid (h2zrf6) (6ci),
dihydrogen,(oc-6-11)-zirconate(2-hexafluoro-, fluorozirconic, Zirconate(2-),hexafluoro-,dihydrogen, DIHYDROGEN HEXAFLUOROZIRCONATE, FLUOROZIRCONIC ACID, HEXAFLUOROZIRCONIC ACID, Dihydrogen hexafluorozirconate solution, Hexafluorozirconic acid solution, dihydrogen,(oc-6-11)-zirconate(2-hexafluoro-, fluorozirconic, Zirconate(2-),hexafluoro-,dihydrogen, DIHYDROGEN HEXAFLUOROZIRCONATE, FLUOROZIRCONIC ACID, HEXAFLUOROZIRCONIC ACID, Dihydrogen hexafluorozirconate solution, Hexafluorozirconic acid solution,



HFZA (Hexafluorozirconic acid) is a colorless, odorless liquid mixture, completely soluble in water and stable under recommended storage conditions.
HFZA (Hexafluorozirconic acid) is corrosive to metals.
HFZA (Hexafluorozirconic acid) is incompatible with strong acids, bases, and should be stored away from metals as contact with metals
can result in the release of hydrogen gas that can be explosive.


This mixture is predominantly composed of 45% dihydrogen hexafluorozirconate(2-),
54.5% water and hydrofluoric acid comprising approximately 0.5%.
Given HFZA (Hexafluorozirconic acid)'s major uses, the primary exposure to this chemical occurs in the industrial setting.


HFZA (Hexafluorozirconic acid) is an inorganic compound that exists in two forms: a solid and a liquid.
HFZA (Hexafluorozirconic acid) is a highly reactive compound that is used in a variety of scientific and industrial applications.
HFZA (Hexafluorozirconic acid) is light green liquid.


HFZA (Hexafluorozirconic acid) is based surface pretreatments on steel for corrosion resistance.
HFZA (Hexafluorozirconic acid) is non flammable.
HFZA (Hexafluorozirconic acid) is an inorganic compound aqueous solution used mainly in the manufacturing of optical glass and fluozirconate, in the metal industry as a corrosion inhibitor for surface pre-treatment.


HFZA (Hexafluorozirconic acid) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
HFZA (Hexafluorozirconic acid) appears as a colorless liquid with a pungent odor.
The basic structure of HFZA (Hexafluorozirconic acid) consists of two hydrogen atoms, one zirconium atom, and six fluorine atoms.


HFZA (Hexafluorozirconic acid) is highly soluble in water.
HFZA (Hexafluorozirconic acid) is important to handle this chemical with caution and use appropriate protective measures.
HFZA (Hexafluorozirconic acid), also known as hydrogen zirconium fluoride, is a chemical compound that finds various applications in industries such as pharmaceuticals, electronics, ceramics, and metal surface treatment.



USES and APPLICATIONS of HFZA (HEXAFLUOROZIRCONIC ACID):
HFZA (Hexafluorozirconic acid) is used as a cleaning and etching agent in the casting and ceramic industries to remove metal surface oxides and other impurities.
HFZA (Hexafluorozirconic acid) is employed as a raw material for preparing catalysts and complexes.


HFZA (Hexafluorozirconic acid) is applied in surface treatments and electroplating to enhance material properties such as corrosion resistance, wear resistance, and heat resistance.
HFZA (Hexafluorozirconic acid) is utilized in the production of compounds like zirconium fluoride and aluminum fluoride.


HFZA (Hexafluorozirconic acid) is used in the preparation of electronic materials for batteries, capacitors, optoelectronic devices, and similar applications.
HFZA (Hexafluorozirconic acid) is used commonly in industrial settings as a precursor material for the manufacture of films used to coat ceramics, to synthesize glass used in prescription eyeglasses and as a common corrosion inhibitor on steel and other metal surfaces.


HFZA (Hexafluorozirconic acid) is primarily used as a catalyst in the synthesis of organic compounds, as a reagent in the synthesis of fluorinated compounds, and as a reagent for the production of fluorinated polymers.
HFZA (Hexafluorozirconic acid) is also used in the manufacture of semiconductor materials and in the production of high-strength glass.


HFZA (Hexafluorozirconic acid) has multiple uses in inorganic chemical reactions such as the preparation of titanium oxide photocatalysts and zirconium oxide thin films.
HFZA (Hexafluorozirconic acid) is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Other release to the environment of HFZA (Hexafluorozirconic acid) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Other release to the environment of HFZA (Hexafluorozirconic acid) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).


HFZA (Hexafluorozirconic acid) can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery).
HFZA (Hexafluorozirconic acid) is used in the following products: laboratory chemicals.
HFZA (Hexafluorozirconic acid) is used in the following products: metal surface treatment products.


Release to the environment of HFZA (Hexafluorozirconic acid) can occur from industrial use: formulation of mixtures.
HFZA (Hexafluorozirconic acid) is used in the following products: laboratory chemicals.
HFZA (Hexafluorozirconic acid) has an industrial use resulting in manufacture of another substance (use of intermediates).


HFZA (Hexafluorozirconic acid) is used for the manufacture of: fabricated metal products.
Release to the environment of HFZA (Hexafluorozirconic acid) can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and in processing aids at industrial sites.


Release to the environment of HFZA (Hexafluorozirconic acid) can occur from industrial use: manufacturing of the substance.
HFZA (Hexafluorozirconic acid) is used common corrosion inhibitor on steel and other metal surfaces; replacement of phosphates for the treatment of zinc-galvanized and cold –roll steel; non-chromium surface passivation; active component in thin-film coatings


HFZA (Hexafluorozirconic acid) is mainly used as corrosion inhibitor by customers active in the metal and coatings industry.
HFZA (Hexafluorozirconic acid) does show highest effectiveness on aluminium though it can be used on other metals as well.
Customers are using Hexafluorozirconic acid as an alternative of nickel based products with less hazardous properties when it comes to environmental as well as health & safety related regulations.


HFZA (Hexafluorozirconic acid) is used electroplating, and aluminum lacquering in chrome-free processes.
HFZA (Hexafluorozirconic acid) is used synthesis of fluoride releasing dental monomers, as a precursor of ZrO2 ceramic films as well as metal surface passivation.


HFZA (Hexafluorozirconic acid) reduces the occurrence of sludge as a side product – e.g. in Zincphosphate based systems.
HFZA (Hexafluorozirconic acid) is used in the pre-treatment of aluminum prior to surface finishing, for example, prior to painting aluminum beverage cans, automotive surfaces and appliances.


HFZA (Hexafluorozirconic acid) is also used in optical glass, zirconium fluoride acid salt manufacturing, in chromate solution can improve the corrosion resistance of steel, zinc, lead and other metals.
HFZA (Hexafluorozirconic acid) is most effective on aluminum, but can also be used on other metals.


HFZA (Hexafluorozirconic acid) is used preparation of titania photocatalyst synthesized from ionic-liquid-like precursor.
HFZA (Hexafluorozirconic acid) is used synthesis of fluoride-releasing dental monomer.
HFZA (Hexafluorozirconic acid) is used as precursor to ZrO2 ceramic thin films.


HFZA (Hexafluorozirconic acid) is mainly used in manufacturing of optical glass and fluozirconate.
HFZA (Hexafluorozirconic acid) is mainly used in manufacturing of optical glass and fluozirconate.
HFZA (Hexafluorozirconic acid) is mainly used in metal surface treatment and cleaning


HFZA (Hexafluorozirconic acid)'s also used in the wool, leather industry and the atomic energy industry and advanced electrical materials, refractory production etc.
HFZA (Hexafluorozirconic acid) is used for metal surface treatment and cleaning, as well as for atomic energy industry and production of advanced electrical materials and refractories.


HFZA (Hexafluorozirconic acid) is used for metal surface treatment and cleaning, as well as for wool, leather garment industry, atomic energy industry and production of high-grade electrical materials and refractories.
HFZA (Hexafluorozirconic acid) is used for metal surface and coating.


Used for: HFZA (Hexafluorozirconic acid) is based surface pretreatments on steel for corrosion resistance.
HFZA (Hexafluorozirconic acid) is used preparation of titania photocatalyst synthesized from ionic-liquid-like precursor Synthesis of fluoride-releasing dental monomer As precursor to ZrO2 ceramic thin films.


HFZA (Hexafluorozirconic acid) is used for metal surface treatment and cleaning, also used in the atomic energy industry and advanced electrical materials, refractory production
HFZA (Hexafluorozirconic acid) is commonly used for etching glass, ceramics, and metals, as a corrosion inhibitor, and as a catalyst in chemical reactions.


HFZA (Hexafluorozirconic acid) is also utilized in the manufacturing of zirconium compounds and as a raw material in the production of metal coatings.
HFZA (Hexafluorozirconic acid) is used in the pre-treatment of aluminum prior to surface finishing, for example, prior to painting aluminum beverage cans, automotive surfaces and appliances.


HFZA (Hexafluorozirconic acid) is also used in optical glass, zirconium fluoride acid salt manufacturing, in chromate solution can improve the corrosion resistance of steel, zinc, lead and other metals.


-Use in Nanoceramic-Based Conversion Coatings:
HFZA (Hexafluorozirconic acid) is also employed as an eco-friendly conversion coating for steel, influencing the morphology and corrosion resistance of the coating.
The optimal performance of HFZA (Hexafluorozirconic acid) is observed at specific solution pH and temperatures.



SCIENTIFIC RESEARCH APPLICATIONS OF HFZA (HEXAFLUOROZIRCONIC ACID):
Corrosion Protection and Surface Treatment: Hexafluorozirconic acid is used for treating steel surfaces.
It forms a zirconium oxide layer on steel, enhancing hydrophobicity and corrosion resistance.
This treatment is effective against corrosion in environments like a 0.5M NaCl solution.



ELECTROCHEMICAL BEHAVIOR IN COATING FORMATION OF HFZA (HEXAFLUOROZIRCONIC ACID):
The electrochemical behavior of HFZA (Hexafluorozirconic acid) in conversion coating formation on steel is notable.
The coating's polarization resistance is influenced by immersion time and bath pH, affecting corrosion resistance.



MARKET PROSPECTS OF HFZA (HEXAFLUOROZIRCONIC ACID):
The demand for HFZA (Hexafluorozirconic acid) is expected to witness steady growth in the coming years.
HFZA (Hexafluorozirconic acid)'s versatile applications and its significance in multiple industries drive its market prospects.
The increasing use of HFZA (Hexafluorozirconic acid) in the electronics industry, particularly in the production of semiconductors and integrated circuits, is a significant factor contributing to its market growth.
Additionally, the growing demand for advanced ceramics and metal surface treatments is further expected to propel the market for HFZA (Hexafluorozirconic acid).



PHYSICAL and CHEMICAL PROPERTIES of HFZA (HEXAFLUOROZIRCONIC ACID):
Boiling point: 100℃[at 101 325 Pa]
Density: 1.512 g/mL at 25 °C
solubility: Miscible with acid-base solutions.
form: Liquid
Exposure limits ACGIH: TWA 5 mg/m3; STEL 10 mg/m3
NIOSH: IDLH 25 mg/m3; TWA 5 mg/m3; STEL 10 mg/m3
Stability: Stable.
Incompatible with acids, oxidizing agents.
Contact with acids releases hydrogen fluoride.
CAS DataBase Reference: 12021-95-3(CAS DataBase Reference)

EPA Substance Registry System: Zirconate(2-), hexafluoro-, dihydrogen, (OC-6-11)- (12021-95-3)
Molecular Weight: 207.23 g/mol
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0
Exact Mass: 205.910768 g/mol
Monoisotopic Mass: 205.910768 g/mol
Topological Polar Surface Area: 0Ų
Heavy Atom Count: 7
Formal Charge: 0

Complexity: 19.1
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point: No data available

Initial boiling point and boiling range No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point No data available
Autoignition temperature: Not applicable
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility: at 20 °C soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,512 g/mL at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: No data available

CAS: 12021-95-3
Category: Heterocyclic Organic Compound
Molecular Weight: 207.23
Molecular Formula: H2ZrF6
MDL Number: MFCD00082965
Density: 1.512 g/mL at 25 °C
Molecular Formula: F6H2Zr
Molecular Weight: 205.215
Flash Point: None
Exact Mass: 203.896225
LogP: 2.74620
Stability: Stable.



FIRST AID MEASURES of HFZA (HEXAFLUOROZIRCONIC ACID):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HFZA (HEXAFLUOROZIRCONIC ACID):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HFZA (HEXAFLUOROZIRCONIC ACID):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HFZA (HEXAFLUOROZIRCONIC ACID):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
required
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HFZA (HEXAFLUOROZIRCONIC ACID):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only
to qualified or authorized persons.
*Storage class:
Storage class (TRGS 510): 6.1D:
Non-combustible



STABILITY and REACTIVITY of HFZA (HEXAFLUOROZIRCONIC ACID):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


HHPA (HEXAHYDROPHTALIC ANHYDRIDE)
HHPA (Hexahydrophtalic Anhydrade) is an organic compound belonging to the class of cyclic anhydrides.
HHPA (Hexahydrophtalic Anhydrade) is a white, solid crystalline material with a melting point of 74-76°C and a molecular weight of 162.15 g/mol.
The chemical formula of HHPA (Hexahydrophtalic Anhydrade) is C8H14O3.


CAS number: 85-42-7
EC number: 201-604-9
MDL Number: MFCD00064863
Molecular Formula: C8H10O3


HHPA (Hexahydrophtalic Anhydrade) is a white solid, soluble in benzene and acetone, moisture adsorption.
Compared with THPA, HHPA (Hexahydrophtalic Anhydrade) has light color and luster, low viscosity, small volatility, low toxicity, small loss on heating, stable performance, long use life, low freezing point and can be long-term stored at room temperature.


HHPA (Hexahydrophtalic Anhydrade) is a white solid or clear liquid if melted with molecular formula C8H10O3.
HHPA (Hexahydrophtalic Anhydrade) is a white crystalline powder
HHPA (Hexahydrophtalic Anhydrade) is a cyclic dicarboxylic anhydride that is the cyclic anhydride of hexahydrophthalic acid.


HHPA (Hexahydrophtalic Anhydrade) is a cyclic anhydride that can be used for a variety of applications such as: plasticizer, rust inhibitor, and a curing agent for epoxy based resins.
HHPA (Hexahydrophtalic Anhydrade) is a cyclic dicarboxylic anhydride that is the cyclic anhydride of hexahydrophthalic acid.


HHPA (Hexahydrophtalic Anhydrade) has high-temperature stability, excellent dielectric properties, and high glass transition temperatures.
HHPA (Hexahydrophtalic Anhydrade) is an alicyclic acid anhydride which has excellent characteristics as a polyester alkyd resin raw material or epoxy resin hardener.


As HHPA (Hexahydrophtalic Anhydrade) does not contain double bond in molecular formula, it can be a raw material of resins with great weather resistance.
When HHPA (Hexahydrophtalic Anhydrade) is used as a raw material of paints or artificial marble, it enhances electric insulation, heat resistance, and chemical resistance.


HHPA (Hexahydrophtalic Anhydrade) is a cyclic dicarboxylic anhydride and a tetrahydrofurandione.
However, HHPA (Hexahydrophtalic Anhydrade) is not usually the direct result of dehydration of the corresponding carboxylic acid.
Instead, HHPA (Hexahydrophtalic Anhydrade) is produced from phthalic anhydride by a nuclear hydrogenation.


The addition of six hydrogen atoms in this reaction gives HHPA (Hexahydrophtalic Anhydrade) its name.
HHPA (Hexahydrophtalic Anhydrade) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.



USES and APPLICATIONS of HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
HHPA (Hexahydrophtalic Anhydrade) is used in the synthesis of polyester resin.
HHPA (Hexahydrophtalic Anhydrade) is used as modifier of alkyd resin.
HHPA (Hexahydrophtalic Anhydrade) is used as curing accelerant in the pasting of epoxy resin.


HHPA (Hexahydrophtalic Anhydrade) is used as material of insecticide.
HHPA (Hexahydrophtalic Anhydrade) is used as material of drug
HHPA (Hexahydrophtalic Anhydrade) is used in plasticizer and antirust.


HHPA (Hexahydrophtalic Anhydrade) is mainly used for the synthesis of polyester resin and normal temperature curing alcohol acid resin, also use as an epoxy resin coating curing accelerator, which can improve curing speed.
HHPA (Hexahydrophtalic Anhydrade)'s groups and uses include adhesives and sealants, industrial chemicals, coatings, and paints.


Other applications of HHPA (Hexahydrophtalic Anhydrade) include industrial use as a monomer in the manufacture of resins, industrial use as an intermediate in chemical synthesis or processing, industrial use as a hardener for epoxy resins, and the manufacture of substances (liquids and flakes).
HHPA (Hexahydrophtalic Anhydrade) is used intermediate, used in coatings, curing agents for epoxy resins, adhesives, plasticizers, etc.


HHPA (Hexahydrophtalic Anhydrade) is used in a variety of applications, such as in the synthesis of polymers, as a reagent in organic synthesis, and as a curing agent for epoxy resins.
HHPA (Hexahydrophtalic Anhydrade) is used in Adhesives & Sealants, Industrial Chemicals, Coatings, Paints


HHPA (Hexahydrophtalic Anhydrade) is used in coatings, epoxy resin solidifying agents, polyester resin, adhesive, plasticizers etc.
HHPA (Hexahydrophtalic Anhydrade) is used when maximum resistance to yellowing and premium optical and electrical performance are required.
Application examples of HHPA (Hexahydrophtalic Anhydrade): Production of polyester resins, binders and paints, use as anhydride for curing epoxy resins, raw material for PVC plasticizers, intermediate product for alkyd resins and rust inhibitors


HHPA (Hexahydrophtalic Anhydrade) is used in coatings, epoxy resin curing agents, adhesives, plasticizers, etc.
HHPA (Hexahydrophtalic Anhydrade) is primarily used as a hardener in epoxy resin systems.
HHPA (Hexahydrophtalic Anhydrade) is a known respiratory sensitiser.


HHPA (Hexahydrophtalic Anhydrade), in combination with triethaylamine (TEA), can be used as a polymerization initiator in the preparation of polyester based resins.
HHPA (Hexahydrophtalic Anhydrade) can also be used as a hardener to cure 1,4-butanediol diglycidyl ether which can be used as an epoxy based system for electronic devices.


HHPA (Hexahydrophtalic Anhydrade) is used intermediate for alkyds, plasticizers, insect repellents, and rust inhibitors; hardener in epoxy resins.
HHPA (Hexahydrophtalic Anhydrade) is mainly used as intermediate for coating resins, plasticizers, insect repellents and rust inhibitors, and as hardener for epoxy resins.


HHPA (Hexahydrophtalic Anhydrade) is preferred over other cyclic anhydrides in casting and coating applications for his higher resistance to yellowing.
HHPA (Hexahydrophtalic Anhydrade) is widely used for electronics applications.
HHPA (Hexahydrophtalic Anhydrade) cured epoxy resins have excellent dielectric properties, high-temperature stability, and high glass transition temperatures.


HHPA (Hexahydrophtalic Anhydrade) is used as a curing agent in adhesive coatings and sealant materials, e.g. for the second-generation two-part epoxy adhesive synthesis.
HHPA (Hexahydrophtalic Anhydrade) is also used in the manufacture of alkyd and polyester resins, insecticides, and rust preventives.


HHPA (Hexahydrophtalic Anhydrade), in combination with triethaylamine (TEA), can be used as a polymerization initiator in the preparation of polyester based resins.
HHPA (Hexahydrophtalic Anhydrade) can also be used as a hardener to cure 1,4-butanediol diglycidyl ether which can be used as an epoxy based system for electronic devices.


HHPA (Hexahydrophtalic Anhydrade) is a cyclic anhydride that can be used for a variety of applications such as: plasticizer, rust inhibitor, and a curing agent for epoxy based resins.
HHPA (Hexahydrophtalic Anhydrade) is mainly used as an intermediate for coating resins (alkyds, polyesters), plasticizers, sealant, curing agent in adhesive, insect repellents, rust inhibitors, electronics applications.


HHPA (Hexahydrophtalic Anhydrade)’s low melt viscosity, as well as its high mix ratio with epoxy resins, makes it particularly suitable as hardener for epoxy resin for applications where high filler loadings are required.
HHPA (Hexahydrophtalic Anhydrade) is preferred over other aromatic anhydrides in casting and coating applications for his higher resistance to yellowing.


HHPA (Hexahydrophtalic Anhydrade) is a saturated dicarboxylic anhydride and will undergo most of the reactions typical of this class of compounds.
HHPA (Hexahydrophtalic Anhydrade) is supplied as a white low-melting solid (38°C) which is miscible with most organic solvents.
In water, HHPA (Hexahydrophtalic Anhydrade) hydrolyzes to hexahydrophthalic acid.


HHPA (Hexahydrophtalic Anhydrade) is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
HHPA (Hexahydrophtalic Anhydrade) is used in the following products: coating products and polymers.
HHPA (Hexahydrophtalic Anhydrade) is used for the manufacture of: machinery and vehicles.


Other release to the environment of HHPA (Hexahydrophtalic Anhydrade) is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).
HHPA (Hexahydrophtalic Anhydrade) is used in the following products: polymers.


Release to the environment of HHPA (Hexahydrophtalic Anhydrade) can occur from industrial use: formulation of mixtures and as processing aid.
HHPA (Hexahydrophtalic Anhydrade) is used in the following products: polymers and coating products.
HHPA (Hexahydrophtalic Anhydrade) is used in the following areas: formulation of mixtures and/or re-packaging.


HHPA (Hexahydrophtalic Anhydrade) is used for the manufacture of: chemicals and .
Release to the environment of HHPA (Hexahydrophtalic Anhydrade) can occur from industrial use: for thermoplastic manufacture, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.


Release to the environment of HHPA (Hexahydrophtalic Anhydrade) can occur from industrial use: manufacturing of the substance.
HHPA (Hexahydrophtalic Anhydrade) is a bio-based direct drop-in for petrochemical HHPA, a speciality chemical which finds application in durable, high gloss, weather-resistant coatings, and high-end electrical applications.


HHPA (Hexahydrophtalic Anhydrade) is a very effective curing agent for epoxy resins.
HHPA (Hexahydrophtalic Anhydrade) is also used in the preparation of alkyd and polyester resins where good color stability is important.
HHPA (Hexahydrophtalic Anhydrade)cured epoxies are characterized by reduced color and improved electrical and physical properties as compared to amine-cured products.


The low melting point of HHPA (Hexahydrophtalic Anhydrade) allows it to be easily handled and blended with liquid resins.
Viscosities of the HHPA (Hexahydrophtalic Anhydrade)-epoxy mixtures are lower, pot life is extended in the absence of catalyst and curing reaction is less exothermic than with other hardeners.


Areas of application of HHPA (Hexahydrophtalic Anhydrade) including casting, laminating, embedding, coating, and impregnating electrical components.
HHPA (Hexahydrophtalic Anhydrade) is mainly used in paints, epoxy curing agents, the polyester resins, adhesives, plasticizers, intermediates to prevent rust, etc.


HHPA (Hexahydrophtalic Anhydrade) is used as a curing agent for epoxy resins and an intermediate for plasticizers and other chemicals.
HHPA (Hexahydrophtalic Anhydrade) is used in the chemical, polymers, paints, lacquers, and varnishes industries.
As HHPA (Hexahydrophtalic Anhydrade) is also useful as an epoxy resin hardener which can produce clear and colorless hardened materials, it is used in LED.


HHPA (Hexahydrophtalic Anhydrade) is also used as a raw material of resist inks, pharmaceuticals, agricultural chemicals, etc.
As HHPA (Hexahydrophtalic Anhydrade) is excellent in impregnating ability, it is used in molding or casting of FRP.
HHPA (Hexahydrophtalic Anhydrade) is mainly used in the chemical industry as a monomer for polymerization processes.


HHPA (Hexahydrophtalic Anhydrade) is used as a starting material for the manufacture of polyester resins, binders and paints.
Among other things, HHPA (Hexahydrophtalic Anhydrade) contributes to greater weather resistance of the polymerization product and better resistance to UV light.


HHPA (Hexahydrophtalic Anhydrade) belongs to the cyclic carboxylic acid anhydrides.
Compared to phthalic anhydride and isophthalic acid, which are cheaper to produce, HHPA (Hexahydrophtalic Anhydrade) also causes the polymers produced to have a lower viscosity.



SYNTHESIS METHOD OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
HHPA (Hexahydrophtalic Anhydrade) is synthesized by the reaction of hexahydrophthalic acid with phthalic anhydride in the presence of a catalytic amount of sulfuric acid.
The reaction is carried out at a temperature of 130-140°C for a period of 1-2 hours.
The reaction produces an anhydride with a yield of 90-95%.



SYNTHESIS METHOD DETAILS OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
Design of the Synthesis Pathway:
The synthesis pathway of HHPA (Hexahydrophtalic Anhydrade) involves the catalytic hydrogenation of the corresponding phthalic anhydride.
This reaction is carried out under high pressure and high-temperature conditions to produce the desired product.



STARTING MATERIALS OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
*Phthalic anhydride
*Hydrogen gas
*Catalyst (e.g. Raney Nickel, Platinum, Palladium)



REACTION OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
Phthalic anhydride is dissolved in a suitable solvent such as methanol or ethanol.
The catalyst is added to the solution and stirred to ensure homogeneity.
Hydrogen gas is then introduced into the reaction vessel under high pressure and high temperature conditions (e.g. 50-100 bar, 150-200°C).
The reaction mixture is stirred for several hours until the desired conversion is achieved.
HHPA (Hexahydrophtalic Anhydrade) is then isolated by filtration or distillation and purified by recrystallization or chromatography.



SCIENTIFIC RESEARCH APPLICATIONS OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
HHPA (Hexahydrophtalic Anhydrade) has been studied for its potential applications in various areas of scientific research.
HHPA (Hexahydrophtalic Anhydrade) has been used as a reagent in the synthesis of polymers, as a curing agent for epoxy resins, and as a catalyst in organic synthesis.
HHPA (Hexahydrophtalic Anhydrade) has also been used in the synthesis of polyesters, polyamides, and polyurethanes, as well as in the synthesis of dyes and pigments.



MECHANISM OF ACTION OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
HHPA (Hexahydrophtalic Anhydrade) is a cyclic anhydride, which reacts with primary and secondary amines to form amides.
This reaction is catalyzed by a small amount of sulfuric acid, and is carried out at a temperature of 130-140°C.
The amides formed are highly stable and can be used in a variety of applications.



BIOCHEMICAL AND PHYSIOLOGICAL EFFECTS OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
HHPA (Hexahydrophtalic Anhydrade) has been studied for its potential biochemical and physiological effects.
HHPA (Hexahydrophtalic Anhydrade) has been found to be non-toxic and non-irritating to the skin, eyes, and mucous membranes.
HHPA (Hexahydrophtalic Anhydrade) has also been found to be non-carcinogenic, non-mutagenic, and non-teratogenic.

Advantages and Limitations for Lab Experiments HHPA (Hexahydrophtalic Anhydrade) has several advantages for use in laboratory experiments.
HHPA (Hexahydrophtalic Anhydrade) is relatively inexpensive, and is readily available from chemical suppliers.
HHPA (Hexahydrophtalic Anhydrade) is also relatively easy to synthesize, and can be used in a variety of applications.

However, HHPA (Hexahydrophtalic Anhydrade) has some limitations.
HHPA (Hexahydrophtalic Anhydrade) is a highly reactive compound, and should be handled with caution.
HHPA (Hexahydrophtalic Anhydrade) should also be stored in an airtight container, away from heat and direct sunlight.



FUTURE DIRECTIONS OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
HHPA (Hexahydrophtalic Anhydrade) has potential applications in a variety of areas.
HHPA (Hexahydrophtalic Anhydrade) could be used in the synthesis of new polymers and materials, as a curing agent for epoxy resins, and as a catalyst in organic synthesis.

HHPA (Hexahydrophtalic Anhydrade) could also be used in the synthesis of dyes and pigments, and in the production of pharmaceuticals and agrochemicals.
Additionally, HHPA (Hexahydrophtalic Anhydrade) could be used in the synthesis of polyesters, polyamides, and polyurethanes, and in the production of adhesives and coatings.
Finally, HHPA (Hexahydrophtalic Anhydrade) could be used in the synthesis of specialty chemicals, such as surfactants and emulsifiers.



PRODUCTION OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
HHPA (Hexahydrophtalic Anhydrade) is obtained by reacting ciscyclohexane-1, 2-dicarboxylic acid with oxalyl chloride.
Combine ciscyclohexane-1, 2-dicarboxylic acid (1 mmol, 172 mg) and oxalyl chloride (1.2 mmol, 152 mg, 0.103 ml) in dry toluene (5 mL) and add a drop of freshly distilled DMF.
Purge the reaction vessel with argon and heat the reaction under stirring for 3 h.

Stop the stirring, decant the toluene solution and filter.
Evaporate the volatiles.
Transform into crystalline form by trituration with diethyl ether.



PURIFICATION METHODS OF HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
HHPA (Hexahydrophtalic Anhydrade) has been obtained by heating the trans-acid or anhydride at 200oC.



PHYSICAL and CHEMICAL PROPERTIES of HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
Boiling point: 296 °C
Density @ 40°C: 1.193 g/ml
Viscosity @ 40°C: 47.0 mPa.s
Vapour pressure @ 120°C: 3.7 mmHg
Melting point: 32-34 °C(lit.)
Boiling point: 158 °C17 mm Hg(lit.)
Density: 1.18
vapor pressure: 0.31Pa at 25℃
refractive index: 1.4620 (estimate)
RTECS: NP6895168
Flash point: >230 °F
storage temp.: Store below +30°C.
solubility: Chloroform, Methanol (Slightly)
form: Solid

pka: 4.14[at 20 ℃]
color: White to Off-White
Water Solubility: 4.2g/L at 20℃
Sensitive: Moisture Sensitive
BRN: 83213
Exposure limits ACGIH: Ceiling 0.005 mg/m3
Stability: Moisture Sensitive
LogP: -4.14 at 20℃
Boiling point: 564.8°F
Molecular weight: 154.17
Freezing point/melting point: 89.6°F
Vapor pressure: 5.35x10(-2)
Flash point: 300.2°F
Vapor density: 1.19
Specific gravity: 5.3

Molecular Weight: 154.16 g/mol
XLogP3-AA: 1.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 0
Exact Mass: 154.062994177 g/mol
Monoisotopic Mass: 154.062994177 g/mol
Topological Polar Surface Area: 43.4Ų
Heavy Atom Count: 11
Formal Charge: 0
Complexity: 187
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Physical state: solid
Color: white
Odor: aromatic
Melting point/freezing point:
Melting point/range: 32 - 34 °C - lit.
Initial boiling point and boiling range: 158 °C at 23 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 4,2 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 1,59 at 40 °C
Vapor pressure: 0,77 hPa at 20 °C
Density: 1,191 g/cm3 at 40 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

Molecular Formula: C8H10O3
Molar Mass: 154.16
Density: 1.236g/cm3
Melting Point: 29-32℃
Boling Point: 283.351°C at 760 mmHg
Flash Point: 143.909°C
Solubility: Soluble in benzene, acetone, etc.
Vapor Presure: 0.003mmHg at 25°C
Appearance: White-like crystal
Storage Condition: Room Temprature
Sensitive: Hygroscopic
Refractive Index: 1.502
MDL: MFCD00005926

Molecular Formula: C8H10O3
Molecular Weight: 154.16 g/mol
IUPAC Name: 3a,4,5,6,7,7a-hexahydro-2-benzofuran-1,3-dione
InChI: InChI=1S/C8H10O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h5-6H,1-4H2
InChI Key: MUTGBJKUEZFXGO-UHFFFAOYSA-N
SMILES: C1CCC2C(C1)C(=O)OC2=O
Canonical SMILES: C1CCC2C(C1)C(=O)OC2=O
Boiling Point: 296 °C, 564.8°F
Color/Form: Clear, colorless, viscous liquid
... becomes a glassy solid at 35-36 °C
Density: 1.19 at 40 °C 5.3
Flash Point: 149 °C (open cup) 300.2°F
Melting Point: 32 °C 35-36 °C 89.6°F
Other CAS RN: 14166-21-3 85-42-7
Physical Description:
DryPowder; Other: Solid
SOLID IN VARIOUS FORMS.
Dry powder or solid in various forms, or clear, colorless, viscous liquid.
Solubility: Miscible with benzene, toluene, acetone, carbon tetrachloride,
chloroform, ethanol, and ethyl acetate;
slightly soluble in petroleum ether
In water: 1.76X10+3 mg/L at 25 °C (est)

Solubility in water: reaction
Vapor Density:
Relative vapor density (air = 1): 5.3 1.19
Vapor Pressure 5.35X10-2 mm Hg at 25 °C (est)
Vapor pressure, Pa at 25 °C: 0.9 5.35x10(-2)
Appearance: White solid
Purity: ≥99.0 %
Acid Value(mg KOH/g): 710~740
Iodine Value (Ig/100g): ≤1.0
Free Acid: ≤1.0%
Colour (Pt-Co): ≤50#
Freezing Point: 34-38℃
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 32.00 °C. @ 760.00 mm Hg
Boiling Point: 283.00 to 284.00 °C. @ 760.00 mm Hg (est)
Boiling Point: 158.00 °C. @ 17.00 mm Hg
Vapor Pressure: 0.003000 mmHg @ 25.00 °C. (est)
Flash Point: 291.00 °F. TCC ( 143.90 °C. ) (est)
logP (o/w): 0.762 (est)
Soluble in: water, 1014 mg/L @ 25 °C (est)



FIRST AID MEASURES of HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water:
system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
required
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of HHPA (HEXAHYDROPHTALIC ANHYDRIDE):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
Cyclohexane-1,2-dicarboxylic anhydride
1,3 - Isobenzofurandione hexahydro-
HHPA;cyclohexane-1,2-dicarboxylic anhydride
1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE
Hexahydro-isobenzofuran-1,3-dione
1,3-Isobenzofurandione, hexahydro-
Hexahydrophthalic Anhydride (HHPA)
NT 907
C6H10(CO)2O
Araldite HT 907
RRSYY(Selfotel)-1
Hexahydrophthalic anhydride
85-42-7
Hexahydroisobenzofuran-1,3-dione
HHPA
1,2-Cyclohexanedicarboxylic anhydride
1,3-Isobenzofurandione, hexahydro-
Lekutherm Hardener H
Hexahydrophthalic acid anhydride
Araldite HT 907
Cyclohexane-1,2-dicarboxylic anhydride
1,2-Cyclohexanedicarboxylic acid anhydride
octahydro-2-benzofuran-1,3-dione
NT 907
Hexahydro-2-benzofuran-1,3-dione
NSC 8622
3a,4,5,6,7,7a-hexahydro-2-benzofuran-1,3-dione
hexahydro-1,3-isobenzofurandione
CHEBI:103210
EINECS 201-604-9
Cyclohexane-1,2-dicarboxylic acid anhydride
DTXSID8026515
HSDB 7912
EINECS 238-009-9
(+)-trans-1,2-Cyclohexanedicarboxylic Anhydride
MFCD00064863
1,2-Cyclohexane dicarboxylic anhydride
EC 201-604-9
1,2-Cyclohexanedicarboxylic anhydride, cis + trans
Hexahydrophthalic anhydride(HHPA)
Hexahydroisobenzofuran-1,3-dione
trans-1,2-Cyclohexanedicarboxylic anhydride
1,3-Isobenzofurandione, hexahydro-, trans-
trans-Cyclohexane-1,2-dicarboxylic anhydride
NSC-8622
MFCD00674195
(3aR,7AS)-hexahydroisobenzofuran-1,3-dione
rel-(3aR,7aR)-Hexahydroisobenzofuran-1,3-dione
hexahydrophtalic anhydride
Epitope ID:122664
SCHEMBL15324
3a,4,5,6,7,7a-hexahydroisobenzofuran-1,3-dione
CHEMBL273968
DTXCID906515
NSC8622
Tox21_200661
BBL011768
STK387488
Hexahydro-2-benzofuran-1,3-dione #
2,4,5,6-tetrahydrophthalic anhydride
AKOS000119684
AKOS016352936
CS-W018047
DS-4586
SB44842
CAS-85-42-7
NCGC00248785-01
NCGC00258215-01
AC-19638
SY234482
LS-183520
C1417
C1657
FT-0623877
FT-0627011
FT-0637021
FT-0657907
FT-0659322
EN300-18014
D70901
A841328
A855212
J-501171
J-521450
Q26840977
Z57127491
F0001-0429
1,2-Cyclohexanedicarboxylic acid anhydride predominately cis
1,2-Cyclohexanedicarboxylic acid anhydride
Araldite HT 907
HHPA
Hexahydrophthalic acid anhydride
Lekutherm Hardener H
1,3-Isobenzofurandione, hexahydro-
Cyclohexane-1,2-dicarboxylic anhydride;
hexahydroisobenzofuran-1,3-dione
HHPA
1,2-cyclohexanedicarboxylic anhydride
Cyclohexane-1,2-dicarboxylic anhydride
1,2-cyclohexanedicarboxylic anhydride
hexahydrophthalic anhydride
HHPSA
HH-PSA
HHPA
1,2-Cyclohexanedicarboxylic acid anhydride,
cyclohexane-1,2-dicaboxylic anhydride,
cis and trans mixture
HHPA
HHPAA
hexahydrophthalic acid anhydride
hexahydro-1,3-isobenzofurandione
cis-hexahydrophthalic anhydride
hhpa,hexahydrophthalic anhydride
hexahydrophthalic acid anhydride
cis-hhpa
hexahydro-2-benzofuran-1,3-dione
cis-hexahydroisobenzofuran-1,3-dione
hhpa
3-isobenzofuranedione,hexahydro-,cis-1
hhpa),cis-1,2-cyclohexanedicarboxylican
1,3-isobenzofurandione, hexahydro-, cis-
HHPA
cis-HHPA
cis-Hexahydrophthalic anhydride
hexahydro-2-benzofuran-1,3-dione
cis-1,2-Cyclohexanedicarboxylic anhydride
(3aR,7aS)-hexahydro-2-benzofuran-1,3-dione
HHPA; 1,2-Cyclohexanedicarboxylic anhydride
1,2-Cyclohexanedicarboxylic Anhydride
1,2-Cyclohexanedicarboxylic Acid Anhydride
Aradur HY 925
Araldite HT 904
Araldite HT 907
Araldite HY 907
Araldite HY 925
Araldite Hardener HY 925
Cyclohexane-1,2-dicarboxylic Acid Anhydride
Cyclohexanedi