DIMETHYLANILINE = N,N-DIMETHYLANILINE = DMA = DIMETHYLAMINOBENZENE
CAS Number: 121-69-7
EC-Number: 204-493-5
MDL number: MFCD00008304
Chemical formula: C8H11N / C6H5N(CH3)2
Dimethylaniline, also known as dimethylaminobenzene or dimethylphenylamine, belongs to the class of organic compounds known as dialkylarylamines.
These are aliphatic aromatic amines in which the amino group is linked to two aliphatic chains and one aromatic group.
Dimethylaniline is a tertiary amine that is aniline in which the amino hydrogens are replaced by two methyl groups.
Dimethylaniline is a tertiary amine and a dimethylaniline.
Dimethylaniline appears as a yellow to brown colored oily liquid with a fishlike odor.
Dimethylaniline is less dense than water and insoluble in water.
Dimethylaniline's flash point is 150 °F.
Dimethylaniline (DMA) is an organic chemical compound, a substituted derivative of aniline.
Dimethylaniline consists of a tertiary amine, featuring dimethylamino group attached to a phenyl group.
The chemical formula for dimethylaniline is C8H11N, and it's molecular weight is 121.18 g/mol.
Dimethylaniline occurs as a yellow oily liquid that is insoluble in water.
The odor threshold for dimethylaniline is 0.013 parts per million (ppm).
The vapor pressure for dimethylaniline is 0.52 mm Hg at 25 °C, and its log octanol/water partition coefficient (log K ow) is 2.31.
Dimethylaniline is less dense than water and insoluble in water.
Dimethylaniline's flash point is 150 °F.
Dimethylaniline (DMA) is an organic chemical compound, a substituted derivative of aniline.
Dimethylaniline consists of a tertiary amine, featuring dimethylamino group attached to a phenyl group.
Dimethylaniline is colourless when pure, but commercial samples are often yellow.
Dimethylaniline, also known as dimethylaminobenzene or dimethylphenylamine, belongs to the class of organic compounds known as dialkylarylamines.
Dimethylaniline is a tertiary amine and a dimethylaniline.
Dimethylaniline belongs to the class of organic compounds known as dialkylarylamines.
Dimethylaniline is a tertiary amine that is aniline in which the amino hydrogens are replaced by two methyl groups.
Dimethylaniline (DMA, CAS No. 121-69-7) belongs to the N-dialkylaminoaromatics, a chemical class structurally alerting to DNA reactivity.
Dimethylaniline (DMA) CAS NO. 121-69-7 also known as N,N-dimethylaniline, dimethylaminobenzene.
Dimethylaniline molecule contains a total of 20 bonds.
Dimethylaniline is a yellow oily liquid, insoluble in water, soluble in ethanol, ether.
Dimethylaniline is a nearly quantitative yield of benzoic acid, N-methyl aniline and formaldehyde .
Outside of the human body, Dimethylaniline has been detected, but not quantified in several different foods, such as common mushrooms, strawberries, feijoa, limes, and black-eyed pea.
No information is available on the reproductive, developmental effects of N,N-dimethylaniline in humans.
Dimethylaniline is colourless when pure, but commercial samples are often yellow.
Dimethylaniline is a tertiary amine that is aniline in which the amino hydrogens are replaced by two methyl groups.
Dimethylaniline is also written as DMA.
Dimethylaniline appears as a yellow to brown colored oily liquid with a fishlike odor.
Dimethylaniline is an important precursor to dyes such as crystal violet.
Less dense than water and insoluble in water.
Dimethylaniline is a tertiary amine that is aniline in which the amino hydrogens are replaced by two methyl groups.
Dimethylaniline appears as a yellow to brown colored oily liquid with a fishlike odor.
Dimethylaniline is less dense than water and insoluble in water.
Outside of the human body, Dimethylaniline has been detected, but not quantified in several different foods, such as common mushrooms, strawberries, feijoa, limes, and black-eyed pea.
USES and APPLICATIONS of DIMETHYLANILINE:
Dimethylaniline is a tertiary amine that is aniline in which the amino hydrogens are replaced by two methyl groups.
Dimethylaniline is a tertiary amine and a dimethylaniline.
Dimethylaniline is used as an intermediate in the manufacture of dyes and other substances.
Dimethylaniline is one of the basic raw materials for the production of basic dyes (triphenylmethane dyes, etc.) and basic dyes.
The main varieties of Dimethylaniline are basic bright yellow, basic purple 5BN, basic green, basic lake blue, and brilliant red 5GN , Bright Blue, etc.
Dimethylaniline is used in the pharmaceutical industry to manufacture cephalosporin V, sulfonamide-b-methoxypyrimidine, sulfa-o-dimethoxypyrim, fluorosporine, etc., and in the perfume industry for the manufacture of vanillin Wait.
Dimethylaniline is used as analytical reagent.
Dimethylaniline is used in the manufacture of spices, pesticides, dyes, explosives, etc.
Dimethylaniline is an important dye intermediate.
Dimethylaniline can be used to prepare basic bright yellow, basic violet 5BN, basic magenta green, basic lake blue BB, basic brilliant blue R, cationic red 2BL, brilliant red 5GN, violet 3BL, brilliant blue, etc.
In the pharmaceutical industry, Dimethylaniline can be used to manufacture cephalosporin V, sulfa-b-methoxypyrimidine, sulfa-o-dimethoxypyrimidine, flucytosine, etc.
Dimethylaniline can be used to produce vanillin in the fragrance industry.
Dimethylaniline can also be used as a solvent, rubber vulcanization accelerator, explosives and raw materials for some organic intermediates.
Dimethylaniline is used determination of methanol, methyl furan formaldehyde, hydrogen peroxide, nitrate, ethanol, formaldehyde and tertiary amines, colorimetric determination of nitrite, etc., solvents, manufacture of vanillin, methyl violet, Michler's ketone and other dyes.
Dimethylaniline is also used in new processes for symmetrical and asymmetrical light conductors.
Dimethylaniline is used as an intermediate in the manufacture of vanillin, Michler's ketone, methyl violet, and other dyes and also as a solvent, an alkylating agent, and a stabilizer.
Dimethylaniline was used to make dyes and as a solvent.
Dimethylaniline is an important precursor to dyes such as crystal violet.
Dimethylaniline was originally developed for use in conjunction with the manufacture of basic dyes, vanillin and Michler's ketone.
Dimethylaniline's applications may be industrial (dye and pesticide intermediates, polymerizing agents) and surgical (polymerization accelerations for the manufacture of bone cements and prosthetic devices), thus implying heterogeneous types of human exposure.
Dimethylaniline is a key precursor to commercially important triarylmethane dyes such as malachite green and crystal violet.
Dimethylaniline is used as curing agent for epoxy resin, as intermediate for organic synthesis, used in the preparation of quatemary amine, dehydrogenation catalyst, preservative and neutralizing agent.
Dimethylaniline is used in the synthesis of vanillin, methyl violet, and Michler's ketone; also used as a hardener for plastic resins and a acid scavenger in the manufacture of semisynthetic penicillins and cephalosporins.
Dimethylaniline serves as a promoter in the curing of polyester and vinyl ester resins.
Dimethylaniline is used as an intermediate in the manufacture of vanillin, Michler's ketone, methyl violet, and other dyes and also as a solvent, an alkylating agent, and a stabilizer.
The Dimethylaniline helps the catalyst to start the chemical reaction between the resin and styrene monomer and form a cured solid.
Dimethylaniline is a promoter used in the curing of polyester and vinyl ester resins.
Dimethylaniline is used in various embedding resin systems such as SPI Chem Low Acid HPMA for Light Microscopy.
Dimethylaniline is mainly used as dye intermediates, solvents, stabilizers, analytical reagents.
Dimethylaniline is used as an intermediate in the manufacture of dyes and other substances.
Dimethylaniline was used to make dyes and as a solvent.
Dimethylaniline has a number of other varied uses, such as with MBTH in a colorimetric peroxidase determination.
Dimethylaniline is also used as a precursor to other organic compounds.
Dimethylaniline is used to make dyes and as a solvent.
Dimethylaniline is a tertiary amine used in the synthesis of several triarylmethane dyes, such as peacock green.
Dimethylaniline is used in Manufacture of Michler's ketone, as reagent for methanol, methyl furfural, hydrogen peroxide, nitrate, alcohol, formaldehyde.
Dimethylaniline can be used on its own with benzoyl peroxide (BPO) type catalysts or in combination with cobalt 6% promoters with methyl ethyl ketone (MEKP) type catalysts.
A study of the in vitro metabolism of Dimethylaniline has confirmed N-demethylation and N-oxidation as metabolic pathways, and has also established ring hydroxylation as a metabolic route.
Dimethylaniline is used in dyes, a rubber vulcanising agent and as a catalyst.
Dimethylaniline is used as a reagent in a sensitive procedure using p-anisidene-N, N-dimethylaniline for the catalytic determination of micro-amounts of ferric and ferrous ions in as little as 10-7 mole.
The purpose of Dimethylaniline is to speed up the curing reaction of polyester and vinyl ester resins and allow them to cure at room temperature.
Dimethylaniline is widely used in manufacturing as a solvent, an intermediate and reagent for.
Dimethylaniline's derivative 2,4-dimethylaniline is a recalcitrant degradant of the pesticide amitraz.
Dimethylaniline is mainly used as dye intermediates, solvents, stabilizers, analytical reagents.
Dimethylaniline is also used in the synthesis of magnetic Gram stains for the detection of bacteria.
Dimethylaniline is a yellowish to brownish oily liquid compound C6H5N(CH3)2 made by methylating aniline and used chiefly as an intermediate in dye manufacture.
SUBSTITUENTS of DIMETHYLANILINE:
*Aniline or substituted anilines
*Dialkylarylamine
*Benzenoid
*Monocyclic benzene moiety
*Organopnictogen compound
*Hydrocarbon derivative
*Aromatic homomonocyclic compound
ALTERNATIVE PARENTS of DIMETHYLANILINE:
*Aniline and substituted anilines
*Organopnictogen compounds
*Hydrocarbon derivatives
PREPARATION and REACTIONS of DIMETHYLANILINE:
Dimethylaniline was first reported in 1850 by the German chemist A. W. Hofmann, who prepared Dimethylaniline by heating aniline and iodomethane:
C6H5NH2 + 2 CH3I → C6H5N(CH3)2 + 2 HI
Dimethylaniline is produced industrially by alkylation of aniline with methanol in the presence of an acid catalyst:
C6H5NH2 + 2 CH3OH → C6H5N(CH3)2 + 2 H2O
Similarly, Dimethylaniline is also prepared using dimethyl ether as the methylating agent.
Dimethylaniline undergoes many of the reactions expected for an aniline, being weakly basic and reactive toward electrophiles.
For example, Dimethylaniline is nitrated to produce tetryl, a derivative with four nitro groups which was once used as explosive.
Dimethylaniline is lithiated with butyllithium.
Methylating agents attack the amine to give the quaternary ammonium salt:
C6H5N(CH3)2 + (CH3O)2SO2 → C6H5N(CH3)3CH3OSO3
PHYSICAL and CHEMICAL PROPERTIES of DIMETHYLANILINE:
Molar mass: 121.183 g·mol−1
Appearance: Colorless liquid
Odor: amine-like
Density: 0.956 g/mL
Melting point: 2 °C (36 °F; 275 K)
Boiling point: 194 °C (381 °F; 467 K)
Solubility in water: 2% (20°C)[1]
Vapor pressure: 1 mmHg (20°C)[1]
Magnetic susceptibility (χ): -89.66·10−6 cm3/mol
Appearance Form: liquid
Color: light yellow
pH: 7,4 at 1,2 g/l at 20 °C
Melting point/freezing point Melting point/range: 1,5 - 2,5 °C - lit.
Initial boiling point and boiling range: 193 - 194 °C - lit.
Flash point: 75 °C - closed cup
Evaporation rate No data available
Flammability (solid, gas): No data available
Vapor pressure: 13 hPa at 70 °C
Vapor density: 4,18 - (Air = 1.0)
Relative density: 0,956 g/cm³ at 25 °C
Water solubility: ca.1 g/l
Partition coefficient: n-octanol/water log Pow: 2,62
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: 1,2 mPa.s at 30 °C
Water Solubility: 14.4 g/L
logP: 2.05
logP: 2.08
logS: -0.92
pKa (Strongest Basic): 5.02
Physiological Charge: 0
Hydrogen Acceptor Count: 1
Hydrogen Donor Count: 0
Polar Surface Area: 3.24 Ų
Rotatable Bond Count: 1
Refractivity: 40.49 m³·mol⁻¹
Polarizability: 14.31 ų
Number of Rings: 1
Molecular Weight: 121.18
XLogP3: 2.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 1
Exact Mass: 121.089149355
Monoisotopic Mass: 121.089149355
Topological Polar Surface Area: 3.2 Ų
Heavy Atom Count: 9
Formal Charge: 0
Complexity: 72.6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance (Clarity): Clear
Appearance (Colour): colourless to pale yellow
Appearance (Form): Liquid
Assay (GC): min. 99.5%
Density (g/ml) @ 20°C: 0.955-0.956
Refractive Index (20°C): 1.557-1.559
Boiling Range: 192-194°C
Iron (Fe): max. 0.0005%
Heavy Metals (Pb): max. 0.0005%
Aniline (GC): max. 0.1%
N-Methyl Aniline (GC): max. 0.1%
Water (KF): max. 0.1%
FIRST AID MEASURES of DIMETHYLANILINE:
-General advice:
Show this material safety data sheet to the doctor in attendance.
-If inhaled:
*After inhalation:
fresh air.
Immediately call in physician.
-In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
-In case of eye contact:
*After eye contact:
rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
-If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
ACCIDENTAL RELEASE MEASURES of DIMETHYLANILINE:
-Personal precautions, protective equipment and emergency procedures:
Ensure adequate ventilation.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of DIMETHYLANILINE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of DIMETHYLANILINE:
-Control parameters:
*Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Latex gloves
Minimum layer thickness: 0,6 mm
Break through time: 60 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of DIMETHYLANILINE:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
STABILITY and REACTIVITY of DIMETHYLANILINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
SYNONYMS:
N,N-Dimethylbenzeneamine
Dimethylaminobenzene
Dimethylphenylamine
N,N-Dimethyl-N-phenylamine
N,N-Dimethylbenzenamine
N,N-Dimethylbenzeneamine
N,N-Dimethylphenylamine
N,N-(Dimethylamino)benzene
N,N-Dimethyl-benzenamine
N,N-Dimethylaniline sulfate (1:1)
N,N-Dimethylaniline hydrochloride
N,N-Dimethylaniline hydroiodide
N,N-dimethylaniline
121-69-7
Dimethylphenylamine
Dimethylaniline
N,N-Dimethylbenzenamin
Benzenamine, N,N-dimethyl-
(Dimethylamino)benzene
N,N-Dimethylphenylamine
N,N-Dimethylbenzeneamine
Dimethylaminobenzene
Dwumetyloanilina
Dimethyl-phenyl-amine
N,N-(Dimethylamino)benzene
Aniline, N,N-dimethyl-
Versneller NL 63/10
NCI-C56428
Dimethylaniline, N,N-
NSC 7195
NL 63-10P
N,N-Dimethylaniline sulfate
N,N-Dimethyl-N-phenylamine
N,N-DIMETHYL-ANILINE
CHEBI:16269
NSC-7195
DSSTox_CID_507
DSSTox_RID_75629
DSSTox_GSID_20507
dimethyl aniline
86362-18-7
CAS-121-69-7
N-N-Dimethylaniline
CCRIS 2381
N, N-Dimethylaniline
HSDB 1179
N,N-dimethylaminobenzene
EINECS 204-493-5
UN2253
dimethyl-anilin
AI3-17284
n-dimethylaniline
N,N-dimethyaniline
N,N-dimethylamline
N,N dimethylaniline
N,N-dimethylaniiine
PhNMe2
n,n,-dimethylaniline
N,N-dirnethylaniline
N,N-dimethyl aniline
UNII-7426719369
N,N-dimethyl-Benzenamine
EC 204-493-5
PhN(CH3)2
SCHEMBL8277
N,N-Dimethylaniline, 99%
MLS002222341
BIDD:ER0332
N,N-Dimethyl-N-phenylamine #
CHEMBL371654
DTXSID2020507
N,N-DIMETHYLANILINE
N,N-Dimethylaniline
N,N-dimethylaniline,sulfuric acid
NSC7195
WLN: 1N1 & R
N,N-DIMETHYLANILINE
N,N-Dimethylaniline, LR, >=99%
Tox21_201813
Tox21_300036
MFCD00008304
STL268843
ZINC12358697
AKOS000119088
UN 2253
NCGC00090724-01
NCGC00090724-02
NCGC00090724-03
NCGC00254056-01
NCGC00259362-01
LS-13434
N,N-DIMETHYLANILINE
SMR001252235
N,N-Dimethylaniline
N,N-Dimethylaniline, ReagentPlus(R), 99%
D0665
D3866
N,N-Dimethylaniline, for synthesis, 99.5%
EN300-18960
C02846
D95371
N,N-Dimethylaniline, SAJ first grade, >=99.0%
Q310473
J-004597
J-523266
F0001-0348
N,N-Dimethylaniline, purified by redistillation, >=99.5%
Benzenamine,N,N-dimethyl-,oxidized,molybdatetungstatephosphates
1000538-06-6
101357-19-1
N,N-Dimethylbenzeneamine
Aniline,N,N-dimethyl
phenyldimethylamine
N,N-Dimethylaniline
N,N-dimethyl-aniline
Benzenamine,N,N-dimethyl
Benzenamine, N,N-dimethyl-
N,N-Dimethylbenzenamine
dimethylphenylamine
N,N-Dimethylphenylamine
Dimethylaminobenzene
Dimethylaniline
Dimethylphenylamine
N,N-Dimethyl-N-phenylamine
N,N-Dimethylbenzenamine
N,N-Dimethylbenzeneamine
N,N-Dimethylphenylamine
N,N-(Dimethylamino)benzene
N,N-Dimethyl-benzenamine
N,N-Dimethylaniline sulfate (1:1)
N,N-Dimethylaniline hydrochloride
N,N-Dimethylaniline hydroiodide
