Sodium 2-hydroxyethyl sulfonate is a colorless, syrupy, strongly acidic liquid that can form detergents with oleic acid.
Sodium 2-hydroxyethyl sulfonate is widely distributed in animal species and in a few red algal species.
Sodium 2-hydroxyethyl sulfonate can be used as an anionic detergent and has anti-settlement activity against Balanus amphitrite.

CAS Number: 1562-00-1
Molecular Formula: C2H5NaO4S
Molecular Weight: 148.11
EINECS Number: 216-343-6

SODIUM ISETHIONATE, 1562-00-1, Isethionic acid sodium salt, Sodium 2-hydroxyethanesulfonate, 2-Hydroxyethanesulfonic acid sodium salt, Sodium hydroxyethylsulfonate, Ethanesulfonic acid, 2-hydroxy-, monosodium salt, Sodium beta-hydroxyethanesulfonate, 2-Hydroxyethanesulfonic acid, sodium salt, DTXSID7027413, Ethanesulfonic acid, 2-hydroxy-, sodium salt (1:1), 3R36J71C17, Sodium 1-hydroxy-2-ethanesulfonate, Sodium 2-hydroxy-1-ethanesulfonate, Sodium 2-hydroxyethanesulfonate, Sodium 2-hydroxyethylsulfonate, Sodium 2-hydroxyethanesulphonate, HSDB 5838, NSC-124283, Sodium 1-hydroxy-2-ethanesulfonate, Sodium 2-hydroxy-1-ethanesulfonate, C2H5NaO4S, EINECS 216-343-6, MFCD00007534, NSC 124283, sodium;2-hydroxyethanesulfonate, UNII-3R36J71C17, Ethanesulfonic acid, 2-hydroxy-, sodium salt, 2-hydroxy-ethanesulfonate, EC 216-343-6, sodium hydroxyethyl sulfonate, Isethionic acid, sodium salt, SCHEMBL125497, CHEMBL172191, DTXCID007413, ISETHIONATE, SODIUM SALT, Sodium 2-Hydroxy-Ethanesulfonate, SODIUM ISETHIONATE [HSDB], SODIUM ISETHIONATE [INCI], LADXKQRVAFSPTR-UHFFFAOYSA-M, Isethionic acid sodium salt, 98%, HY-Y1173, 2-hydroxyethanesulfonic acid; sodium, Tox21_200227, AKOS015912506, NCGC00257781-01, CAS-1562-00-1, SODIUM 2-HYDROXYETHANESULFONIC ACID, CS-0017163, FT-0627314, H0241, A809723, J-009283, Q1969744, F1905-7166

Sodium 2-hydroxyethyl sulfonate is a drug that is used to treat metabolic disorders such as cystinuria and hyperchloremic metabolic acidosis.
Sodium 2-hydroxyethyl sulfonate is also used for the treatment of water-vapor related respiratory problems and cataracts, as well as for the prevention of renal stone formation.
This drug is made through electrochemical impedance spectroscopy of taurine in reaction solution with phosphorus pentoxide.

Sodium 2-hydroxyethyl sulfonate binds to the chloride ion receptor site on the Na+/K+ ATPase, causing an inhibition of the enzyme's function.
Sodium 2-hydroxyethyl sulfonate, is a chemical compound with the molecular formula C2H5NaO4S.
Sodium 2-hydroxyethyl sulfonate is the sodium salt of isethionic acid.

The chemical structure of isethionic acid includes a hydroxyl group (OH) and a sulfonic acid group (SO3H).
Sodium 2-hydroxyethyl sulfonate is commonly used in cosmetic and personal care products, particularly in soap and detergent formulations.
Sodium 2-hydroxyethyl sulfonate functions as a surfactant, which means it helps to reduce the surface tension of liquids and allows them to spread more easily.

In skincare products, Sodium 2-hydroxyethyl sulfonate can contribute to the formation of a stable lather and enhance the cleansing properties of the product.
Sodium 2-hydroxyethyl sulfonate, short chain alkane sulfonate containing hydroxy group, is a water soluble, strongly acidic liquid used in the manufacture of mild, biodegradable and high foaming anionic surfactants which provides gentle cleansing and soft skin feel.

Sodium 2-hydroxyethyl sulfonate is the trivial name for 2-hydroxyethanesulfonic acid which is the parent compound of sodium isethionate.
Sodium 2-hydroxyethyl sulfonate has been shown to increase locomotor activity in rats by improving their biochemical properties.
Sodium 2-hydroxyethyl sulfonate is an organic salt and an important intermediate for pharmaceuticals, cosmetics and daily chemicals.

Sodium 2-hydroxyethyl sulfonate is an organosulfur compound.
Sodium 2-hydroxyethyl sulfonate is prepared by the reaction of ethylene oxide with sodium bisulfite solution.
Sodium 2-hydroxyethyl sulfonate is the sodium salt of 2-hydroxyethane sulfonic acid (isethionic acid), it is used as a hydrophilic head group in washing-active surfactants, known as isethionates (acyloxyethanesulfonates) due to its strong polarity and resistance to multivalent ions.

Sodium 2-hydroxyethyl sulfonate is being studied as a high production volume chemical in the "High Production Volume (HPV) Chemical Challenge Program" of the US Environmental Protection Ministry EPA.
Sodium 2-hydroxyethyl sulfonate is an organosulfur compound containing an alkylsulfonic acid located beta to a hydroxy group.
Sodium 2-hydroxyethyl sulfonate is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group.

Mammals are able to endogenously synthesize Sodium 2-hydroxyethyl sulfonate via taurine through a possible enzymatic deamination process.
Sodium 2-hydroxyethyl sulfonate can be found in both human plasma and urine.
Higher plasma levels of Sodium 2-hydroxyethyl sulfonate have been shown to be protective against type 2 diabetes.

Sodium 2-hydroxyethyl sulfonates discovery is generally attributed to Heinrich Gustav Magnus, who prepared it by the action of solid sulfur trioxide on ethanol in 1833.
Sodium 2-hydroxyethyl sulfonate is a white water-soluble solid used in the manufacture of certain surfactants and in the industrial production of taurine.

Sodium 2-hydroxyethyl sulfonate is most commonly available in the form of its sodium salt (sodium isethionate).
Spectrum Chemical manufactures and distributes fine chemicals with quality can count on including those with CAS number 1562-00-1, Whether call it Isethionic Acid Sodium Salt, 2-Hydroxyethanesulfonic Acid Sodium Salt or Sodium Isethionate can be assured the Isethionic Acid Sodium Salt products offered by Spectrum, meet or exceed the grade requirements or specifications for each individual product.

Melting point: 191-194 °C(lit.)
Density: 1762.7[at 20℃]
storage temp.: Store below +30°C.
solubility: H2O: 0.1 g/mL, clear, colorless
form: Fine Powder
color: White
PH: 7.0-11.0 (20g/l, H2O, 20℃)
Water Solubility: SOLUBLE
BRN: 3633992
Stability: Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong acids.
LogP: -4.6 at 20℃

Sodium 2-hydroxyethyl sulfonate contributes to the stability of formulations by preventing phase separation or changes in texture over time, enhancing the overall shelf life of the product.
Sodium 2-hydroxyethyl sulfonate is recognized by its International Nomenclature of Cosmetic Ingredients (INCI) name, which is the standardized system for naming cosmetic ingredients globally.
Formulators may need to consider the compatibility of Sodium 2-hydroxyethyl sulfonate with different packaging materials to ensure the stability and integrity of the product during storage and use.

Sodium 2-hydroxyethyl sulfonate is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group.
Sodium 2-hydroxyethyl sulfonate is a water-soluble liquid used in the manufacture of mild, biodegradable, and high-foaming anionic surfactants.
These surfactants provide gentle cleansing and a soft skin feel.

Sodium 2-hydroxyethyl sulfonate forms a colourless, syrupy, and strongly acidic liquid that can form detergents with oleic acid.
Sodium 2-hydroxyethyl sulfonate is frequently used in the industrial production of taurine.
Sodium 2-hydroxyethyl sulfonate via taurine through a possible enzymatic deamination process.

Sodium 2-hydroxyethyl sulfonate can be found in both human plasma and urine.
Higher plasma levels of Sodium 2-hydroxyethyl sulfonate have been shown to be protective against type 2 diabetes.
Sodium 2-hydroxyethyl sulfonate is an organosulfur compound.

Sodium 2-hydroxyethyl sulfonate is widely distributed in animal species and in a few red algal species.
Sodium 2-hydroxyethyl sulfonate can be used as an anionic detergent and has anti-settlement activity against Balanus amphitrite.
Sodium 2-hydroxyethyl sulfonate is commonly found in shampoos and hair care products.

Sodium 2-hydroxyethyl sulfonates surfactant properties help in removing oils and dirt from the hair and scalp, contributing to the overall cleansing performance of the product.
Sodium 2-hydroxyethyl sulfonate is often used in the formulation of syndet bars, which are synthetic detergent bars.
These bars are considered milder than traditional soap bars and are popular for cleansing without causing excessive dryness.

Sodium 2-hydroxyethyl sulfonate is generally considered to be biodegradable.
Biodegradability is an important consideration in the formulation of personal care products to minimize environmental impact.
In some formulations, Sodium 2-hydroxyethyl sulfonate is included in toothpaste.

Sodium 2-hydroxyethyl sulfonate is foaming and cleansing properties can contribute to the effectiveness of toothpaste in removing plaque and debris from the teeth.
Sodium 2-hydroxyethyl sulfonate can help to adjust and stabilize the pH of a formulation.
Maintaining the appropriate pH is crucial for the stability and performance of many cosmetic and personal care products.

Sodium 2-hydroxyethyl sulfonate, may be subject to regulations and guidelines set by health authorities in different countries.
Sodium 2-hydroxyethyl sulfonate's important for manufacturers to ensure that their formulations comply with relevant regulations.
Sodium 2-hydroxyethyl sulfonate is commercially available and is used by cosmetic and personal care product manufacturers worldwide.

Sodium 2-hydroxyethyl sulfonate is availability contributes to its widespread use in various formulations.
Ongoing research and development in the cosmetic industry may lead to the discovery of new applications or formulations involving Sodium 2-hydroxyethyl sulfonate, as well as potential improvements in its performance or environmental impact.
Sodium 2-hydroxyethyl sulfonate for synthesis is a high-quality product widely used in various industries.

Known for its superior quality and excellent performance, Sodium 2-hydroxyethyl sulfonate is extensively used in the production of chemicals and pharmaceuticals for its exceptional properties and wide range of applications.
Sodium 2-hydroxyethyl sulfonate can have antistatic properties, which are beneficial in hair care products.
Sodium 2-hydroxyethyl sulfonate helps reduce static electricity, making hair more manageable and less prone to frizz.

Some surfactants may not perform well in hard water, but Sodium 2-hydroxyethyl sulfonate tends to be more compatible.
This makes Sodium 2-hydroxyethyl sulfonate suitable for formulations in areas where hard water is prevalent.
Sodium 2-hydroxyethyl sulfonate's versatility extends to its compatibility with various formulation types, such as liquid cleansers, solid bars, shampoos, and other personal care products.

In addition to its cleansing properties, Sodium 2-hydroxyethyl sulfonate can contribute to a pleasant skin feel in cosmetic formulations, enhancing the overall sensory experience of the product.
As consumer demand for sustainable and eco-friendly products increases, there may be ongoing efforts within the industry to explore and develop more sustainable alternatives or production methods for ingredients like sodium isethionate.
The production of Sodium 2-hydroxyethyl sulfonate involves the reaction of ethylene oxide with sodium bisulfite.

Understanding the manufacturing process is crucial for ensuring the quality and purity of the final ingredient.
Ongoing research in the cosmetic and personal care industry may lead to the exploration of alternative ingredients with similar or improved properties compared to Sodium 2-hydroxyethyl sulfonate.
As consumers become more informed about the ingredients in personal care products, there may be an increased emphasis on providing transparent information about the purpose and safety of ingredients like Sodium 2-hydroxyethyl sulfonate.

Uses:
Sodium 2-hydroxyethyl sulfonate is used in cleaning/washing agents, disinfectants, cosmetics, surface-active agents, shampoos, and bubble baths.
Sodium 2-hydroxyethyl sulfonate is used as a key raw material in the manufacturing of Igepon type surfactants which are ethanesulfonated detergent bars.
Sodium 2-hydroxyethyl sulfonate is used in the following products: cosmetics and personal care products, pH regulators and water treatment products, polymers and textile treatment products and dyes.

Release to the environment of Sodium 2-hydroxyethyl sulfonate can occur from industrial use: formulation of mixtures and formulation in materials.
Sodium 2-hydroxyethyl sulfonate is used in the following products: metal surface treatment products, pH regulators and water treatment products, pharmaceuticals, polymers and textile treatment products and dyes.
Sodium 2-hydroxyethyl sulfonate has an industrial use resulting in manufacture of another substance (use of intermediates).

Sodium 2-hydroxyethyl sulfonate is used for the manufacture of: chemicals, textile, leather or fur and metals.
Release to the environment of Sodium 2-hydroxyethyl sulfonate can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.
Sodium 2-hydroxyethyl sulfonate is an amphoteric detergent used in detergent bar soaps.

Sodium 2-hydroxyethyl sulfonate makes a dense lather in addition to the lather made by the soap.
Sodium 2-hydroxyethyl sulfonate can also be used as the intermediate of shampoo, paste shampoo & detergent in daily chemical industry.
Sodium 2-hydroxyethyl sulfonate is used as the pharmaceutical raw materials, the intermediate of fine chemical products.

Sodium 2-hydroxyethyl sulfonate is a surfactant, so it is frequently used in cleansing products such as facial cleansers, body washes, and hand soaps.
Sodium 2-hydroxyethyl sulfonate helps in emulsifying oils and removing dirt from the skin.
Due to its mild cleansing properties, sodium isethionate is used in hair care products, including shampoos and conditioners.

Sodium 2-hydroxyethyl sulfonate contributes to the formation of a rich lather and aids in cleaning the hair and scalp.
Syndet bars, short for synthetic detergent bars, often contain sodium isethionate.
These bars are milder than traditional soap bars and are popular for use in sensitive skin products.

In some toothpaste formulations, Sodium 2-hydroxyethyl sulfonate may be included to contribute to the foaming action and cleaning properties.
Its antistatic properties make Sodium 2-hydroxyethyl sulfonate suitable for use in hair care products designed to reduce static electricity, making hair more manageable.
Sodium 2-hydroxyethyl sulfonate can be used to adjust and stabilize the pH of formulations.

This is important in maintaining the effectiveness and stability of various cosmetic products.
Sodium 2-hydroxyethyl sulfonate can act as a stabilizing agent in certain formulations, contributing to the overall stability and shelf life of the product.
The hydroxyl group in Sodium 2-hydroxyethyl sulfonate can contribute to the hydrating properties of formulations, making it suitable for use in moisturizing products.

Sodium 2-hydroxyethyl sulfonate is compatible with a wide range of cosmetic ingredients, making it a versatile component in various formulations.
Sodium 2-hydroxyethyl sulfonate is often used in baby care products, such as baby shampoos and body washes, to provide a gentle cleansing experience for delicate skin.
Sodium 2-hydroxyethyl sulfonate can be included in facial cleansers and exfoliating scrubs to help cleanse the face and remove dead skin cells, contributing to a smoother complexion.

Sodium 2-hydroxyethyl sulfonate is sometimes used in combination with other surfactants to achieve specific performance characteristics.
This synergistic effect allows formulators to tailor the properties of the final product.
In addition to cleansers, Sodium 2-hydroxyethyl sulfonate may be included in creams and lotions to contribute to their emulsifying properties and enhance the spreadability of the product on the skin.

In hair care formulations, Sodium 2-hydroxyethyl sulfonate can act as a pH adjuster, helping to maintain the desired pH level for optimal performance of the product.
As consumer demand for sulfate-free products increases, Sodium 2-hydroxyethyl sulfonate can be part of formulations designed to be sulfate-free while still providing effective cleansing.
Sodium 2-hydroxyethyl sulfonateis generally considered biodegradable, which is an important factor for formulators and consumers concerned about the environmental impact of cosmetic ingredients.

In some formulations, Sodium 2-hydroxyethyl sulfonate may be included in hand sanitizers to contribute to the cleansing properties of the product.
Ongoing research in the cosmetic industry may lead to the discovery of new applications or improved formulations involving Sodium 2-hydroxyethyl sulfonate.
Manufacturers need to ensure that products containing Sodium 2-hydroxyethyl sulfonate comply with relevant regulations and safety guidelines established by health authorities in different regions.

As consumer preferences evolve, sodium isethionate may find new applications in response to trends such as natural and organic formulations, cruelty-free products, and other emerging market demands.
Sodium 2-hydroxyethyl sulfonate is mild on the skin, and non-drying.
Sodium 2-hydroxyethyl sulfonate works equally well in soft or hard water.

Sodium 2-hydroxyethyl sulfonate is also an anti-static agent in shampoos.
Sodium 2-hydroxyethyl sulfonate works as an amphoteric detergent and can also be used as an intermediate in preparing surfactants derived from fatty acid sulfoalkyl esters (acyloxy ethane sulfonate).
Sodium 2-hydroxyethyl sulfonate increases the formulation's stability, improves the detergency in hard water, and is smooth to the skin.

Safety Profile:
Sodium 2-hydroxyethyl sulfonate is known for its mildness, but like any cosmetic ingredient, it has the potential to cause irritation in some individuals, particularly those with sensitive skin.
Manufacturers should list all ingredients on product labels, allowing consumers to identify and avoid products containing substances to which they may be sensitive.
Products containing Sodium 2-hydroxyethyl sulfonate are not intended for ingestion.

Ingesting cosmetic products can be harmful, and precautions should be taken to keep them out of reach of children.
Sodium 2-hydroxyethyl sulfonate's advisable to conduct patch tests before widespread use, especially in products intended for sensitive areas like the face.
Care should be taken to avoid contact with eyes.

If contact occurs, rinsing with plenty of water is recommended.
Eye irritation can be a concern with many surfactants, so formulations containing sodium isethionate should be tested for ocular safety.
While Sodium 2-hydroxyethyl sulfonate is generally well-tolerated, some people may be allergic or sensitive to specific ingredients.