prunus serotina bark; cherry bark ; prunus capuli bark; cerasus longifolius bark; plant material derived from the dried stem bark of the wild cherry, prunus serotina, rosaceae CAS NO:84604-07-9

iron blue; Hamburg Blue; Paris Blue; bronze blue; celestial blue; cyanine; Haarlem blue; oriental blue; potash blue; Turnbull's blue Cas no :25869-00-5

psidium guajava fruit extract; extract of the fruit of the guava, psidium guajava l., myrtaceae; guajava pyrifera fruit extract; guava fruit extract; psidium guava fruit extract CAS NO:91770-12-6

4-Methylbenzenesulfonamide; Pasam; p-TSA; PTSA; Toluene-4-sulfonamide; 4-Toluenesulfonic Acid Amide; Para-Toluenesulphonamide; P-Tosylamide; Toluol-4-sulfonamid (German); Tolueno-4-sulfonamida (Spanish); Toluène-4-sulfonamide (French) CAS NO: 70-55-3

cas no: 5131-66-8 Butoxypropanol; 1,2-Propylene glycol 1-monobutyl ether; 1-Butoxy-2-propanol; 2-Hydroxy-3-butoxypropane; Propasol solvent B; Propylene glycol monobutyl ether; n-Butoxy-2-propanol; n-Butoxypropanol; 1-Butoxypropan-2-ol; 2-Propanol, 1-butoxy-; [ChemIDplus] PnB; [Reference #1] Dowanol PNB glycol ether; [Dow Chemical MSDS] PGBE;

cas no 70-55-3 4-Methylbenzenesulfonamide; Pasam; p-TSA; PTSA 70 ; Toluene-4-sulfonamide; 4-Toluenesulfonic Acid Amide; Para-Toluenesulphonamide; P-Tosylamide; Toluol-4-sulfonamid (German); Tolueno-4-sulfonamida (Spanish); Toluène-4-sulfonamide (French); p-TOLUENE SULFONAMIDE 70;

polyvinyl alcohol

ptychopetalum olacoides extract; extract of the bark and root of the potency wood, ptychopetalum olacoides, olacaceae; muira puama extract; muirapuama extract; potency wood extract CAS NO:84929-46-4

SYNONYMS 2,9-Bis(3,5-dimethylphenyl)anthra(2,1,9-def:6,5,10-d',e',f')diisoquinoline-1,3,8,10(2H,9H)-tetrone; EINECS 225-590-9; N,N'-Bis(3,5-dimethylphenyl)-3,4,9,10-perylenetetracarboxylic Diimide; N,N'-Bis(3,5-dimethylphenyl)perylene-3,9,9,10-dicarboximide(Pigment Red 149); 2,9-bis-(3,5- CAS NO:4948-15-6

pueraria lobata root extract; extract of the roots of pueraria lobata, fabacea; kudzu root extract; kudzu root extract; actipone pueraria root CAS NO:223748-08-1

pururan; E1204; α-1,4- ;α-1,6-glucan'. CAS NO:9057-02-7

punica granatum l. bark extract ;extract of the bark of the pomegranate, punica granatum l., punicaceae; pormegranate bark extract; punica florida bark extract; punica grandiflora bark extract; punica nana bark extract; punica spinosa bark extract CAS NO:84961-57-9

amiporine ER extract of the fruit of the pomegranate, punica granatum l., punicaceae pomegranate fruit extract punica florida fruit extract punica grandiflora fruit extract punica nana fruit extract punica spinosa fruit extract CAS Number 84961-57-9

extract of the pericarp of the pomegranate, punica granatum l., punicaceae; extract of the pericarp of the pomegranate, punica granatum l., punicaceae; pomegranate extract BG30; pomegranate pericarp extract; punica florida pericarp extract; punica grandiflora pericarp extract; punica nana pericarp extract; punica spinosa pericarp extract CAS NO:84961-57-9

Purac FCC представляет собой сиропообразную жидкость от бесцветного до желтого цвета.
Purac FCC имеет мягкий кисловатый вкус и широко используется в качестве подкислителя в пищевой промышленности.


Номер CAS: 50-21-5
Номер ЕС: 200-018-0
Названия INCI: МОЛОЧНАЯ КИСЛОТА
Молекулярная формула: C3H6O3.



L-молочная кислота, PURAC 50-100, PURAC 80 FG, PURAC 88-LT, 88-T, PURAC FCC 50, FCC 80, FCC 85, FCC 88, PURAC FIT Plus 90, PURAC HiPure 51, HiPure 90, PURAC HS 50, HS 80, HS 88, HS 90, HS 93, HS 95, HS 100, PURAC PF 90, PURAC PH 91, PURAC UltraPure 50, UltraPure 90, PURAC Vin, PURAC DEX 185, PURAC HS Pure 90, PURAC HS Pure 50, молочная кислота 50% NATL FCC, Purac FCC 50, Unilac LA50, Tisulac, Espiritin, HiPure 90, L-lacticaci, Lactic L-Milchsàure, α-гидроксипропионовая кислота, 2-гидроксипропановая кислота, 2-гидроксипропионовая кислота, 2-гидроксипропановая кислота кислота, DL-молочная кислота, DL-молочная кислота, 2-гидроксипропионовая кислота, Acidum laccum,
Молочная кислота 80% Pdr с силикагелем, молочная кислота 80%, Unilac LA80, Тисулак, Эспиритин, HiPure 90, L-laccaci, L-Milchsàure, α-гидроксипропановая кислота,
молочная кислота, 2-гидроксипропановая кислота, DL-молочная кислота, 50-21-5, 2-гидроксипропионовая кислота,



Purac FCC — это натуральная молочная кислота L(+), которую производят
брожение из сахара.
Основные функции Purac FCC — сохранение и придание вкуса.


Purac FCC – это органическая кислота, используемая в промышленных целях.
Purac FCC представляет собой гидроксикарбоновую кислоту, поэтому содержит как карбоксильную, так и гидроксильную группу.
Поэтому Purac FCC также называют 2-гидроксипропионовой кислотой, но в соответствии с рекомендациями номенклатуры IUPAC следует использовать название 2-гидроксипропионовая кислота.


Химическая формула Purac FCC — C3H6O3.
Purac FCC производится в виде натуральной L-молочной кислоты путем ферментации углеводов, таких как сахар или крахмал.


Purac FCC используется в косметических композициях для регулирования pH и имеет хорошее сродство к коже и волосам.
Purac FCC улучшает гидратацию кожи, удаляет омертвевшие клетки и пленки волос (перхоть), оказывает кератолитическое действие, волосы блестят.
Purac FCC отвечает за резкий запах, который появляется во рту при употреблении в пищу говядины сухого вызревания.


Purac FCC производится в виде натуральной L-молочной кислоты путем ферментации углеводов, таких как сахар или крахмал.
Химическая формула Purac FCC — C3H6O3.
Органическая кислота Purac FCC используется для снижения щелочности без добавления ионов сульфата и хлорида.


Purac FCC может помочь стимулировать выработку коллагена и укрепить кожу, что приводи�� к уменьшению количества тонких линий и морщин.
Гидроксикислоты отшелушивают верхний слой кожи, помогая разгладить и выровнять цвет лица, не засоряют поры, осветляют кожу и даже уменьшают темные пятна и обесцвечивание.


Purac FCC — универсальная органическая кислота.
Purac FCC растворим в воде и этаноле.
Включение дополнительного количества Purac FCC перед сычужным ферментом устраняет этот недостаток и повышает выход творога.


Соли и эфиры Purac FCC называются лактатами.
Концентрированный раствор Purac FCC обычно представляет собой смесь лактата молочной кислоты и молочной кислоты.
Purac FCC представляет собой сиропообразную жидкость от бесцветного до желтого цвета без запаха.


Purac FCC представляет собой жидкость от бесцветного до желтого/коричневого цвета.
Храните Purac FCC в плотно закрытой таре.
Храните Purac FCC в прохладном, сухом, хорошо проветриваемом помещении, вдали от несовместимых веществ.


Purac FCC также можно использовать для небольших корректировок пивоварения. PH можно использовать на более высоких уровнях для сквашивания пива.
Purac FCC снижает уровень щелочности пивоваренного раствора, стимулируя максимальную активность ферментов в сусле и обеспечивая оптимальный уровень pH на протяжении всего процесса пивоварения.


Purac FCC повышает выход экстракта и способность к ферментации.
Purac FCC подходит для пива, в котором не требуются другие анионы, например, для лагеров.
Purac FCC улучшает прозрачность и стабильность готового продукта.


Purac FCC — это готовая к использованию кислота, используемая для снижения щелочности пивоваренного раствора.
Purac FCC соответствует пищевому качеству и производится путем ферментации натурального (свекловичного или тростникового) сахара.
Purac FCC – продукт природного происхождения, полученный путем ферментации глюкозы.


Purac FCC представляет собой альфа-гидроксикислоту (AHA) и может использоваться для ускорения шелушения и обновления клеток.
Purac FCC также является увлажняющим составом.
Purac FCC принадлежит к группе альфа-гидроксикислот (AHA), которые обладают отшелушивающими, увлажняющими и омолаживающими свойствами.


Purac FCC выпускается в бутылочках-капельницах емкостью 4 жидких унции, что позволяет обеспечить точную дозировку молока и добиться стабильных результатов при производстве сыра.
На производстве обычно добавляют Purac FCC так, чтобы pH молока составлял 5,0.
Казеин в ферментированном молоке коагулируется (свертывается) с помощью Purac FCC, и он также отвечает за кислый вкус хлеба на закваске.


Если pH выходит за пределы диапазона 5,3–5,8, постепенно добавляйте (0,10–0,15 мл/л) Purac FCC, перемешайте и повторите измерение.
Purac FCC от компании Jungbunzlauer представляет собой органическую кислоту, естественным образом встречающуюся в организме человека и в ферментированных продуктах.
Purac FCC — натуральный консервант и регулятор pH.


Purac FCC — органическая кислота, имеющая широкое промышленное применение.
Спецификация Purac FCC делает его особенно полезным для производства продуктов питания и напитков, а также фармацевтических и косметических продуктов.
Purac FCC — универсальная органическая кислота.


В жидком состоянии Purac FCC бесцветен.
Purac FCC — одна из альфа-гидроксикислот (AHA).
Эти кислоты встречаются в природе во фруктах, сахарном тростнике и молоке.


Purac FCC повышает кислотность сусла и улучшает как затирание, так и брожение.
Точная дозировка зависит от щелочности используемой воды, добавленных солей и солода, использованного в рецепте.
Purac FCC рекомендуется проводить измерение pH затора перед добавлением продукта.


В природе Purac FCC содержится в кислом молоке, йогуртах, кислых ржаных супах и силосе.
Purac FCC существует в двух оптических формах L и D, из которых только L-молочная кислота является биологически активной и является естественным элементом кожи и волос.
Purac FCC является одним из основных компонентов NMF – естественного увлажняющего фактора, который отвечает за правильное увлажнение эпидермиса.


Purac FCC очень деликатно стабилизирует процесс отшелушивания эпидермиса.
Purac FCC — это альфа-гидроксикислота, обладающая как отшелушивающими, так и увлажняющими свойствами.
Purac FCC естественным образом вырабатывается в организме (это вещество, которое вызывает покалывание во время тренировки), а также содержится в йогурте и молоке.


Purac FCC очень хорошо растворяется в воде.
Purac FCC является натуральным.
Purac FCC одобрен как пищевая добавка E 270.


Purac FCC — это немолочная версия, которая является частью семейства кислот, называемых альфа-гидроксикислотами (AHA).
Purac FCC производится из натурального кукурузного крахмала с помощью передовой технологии биоферментации и очистки.
Purac FCC представляет собой жидкость от желтоватого до бесцветного цвета со слегка кислым запахом и вкусом.


Purac FCC — это встречающаяся в природе альфа-гидроксикислота (или AHA), получаемая путем ферментации сахаров.
Purac FCC — это альфа-гидроксикислота, наиболее часто используемая в продуктах для пилинга.
Purac FCC, также известный как молочная кислота, представляет собой органическое соединение с химической формулой C3H6O3.


Purac FCC является сильной альфа-гидроксикислотой и, следовательно, обладает превосходными отшелушивающими свойствами, хотя они слабее, но уступают гликолевой кислоте.
Продукты AHA должны быть самостоятельным лечебным продуктом и не входить в состав другого продукта.


Хотя AHA могут быть включены в другие продукты, могут возникнуть определенные несовместимости, плюс AHA (из-за pH, необходимого для максимальной эффективности) могут не позволить другим продуктам (например, очищающим маскам) работать должным образом, и наоборот.
Purac FCC также является широко используемым органическим подкислителем, вероятно, потому, что он классифицируется как слабая кислота.


Хотя AHA могут быть включены в другие продукты, могут возникнуть определенные несовместимости, плюс AHA (из-за pH, необходимого для максимальной эффективности) могут не позволять другим продуктам (например, очищающим маскам) работать должным образом, и наоборот.
Purac FCC также является широко используемым органическим подкислителем, вероятно, потому, что он классифицируется как слабая кислота.


Как и во всех производственных процессах, мы рекомендуем провести лабораторные испытания для определения соответствующих количеств.
Purac FCC представляет собой жидкий раствор в воде чистотой около 80%.
Purac FCC — органическая кислота, применяемая в производстве пива, а также в косметической, фармацевтической, пищевой и химической промышленности.


Purac FCC производится из натурального кукурузного крахмала с помощью передовой технологии биоферментации и очистки.
Purac FCC представляет собой жидкость от желтоватого до бесцветного цвета со слабым кисловатым запахом и вкусом.
Purac FCC представляет собой сиропообразную жидкость от бесцветного до желтого цвета без запаха.


Храните Purac FCC в плотно закрытой таре.
Храните Purac FCC в прохладном, сухом, хорошо проветриваемом помещении вдали от несовместимых веществ.
Purac FCC представляет собой сиропообразную жидкость от бесцветного до желтого цвета.


Purac FCC — это альфа-гидроксикислота, получаемая из молока.
В результате относительно большей молекулярной массы кератолитическое действие Purac FCC более мягкое, чем у гликолевой кислоты, что предотвращает раздражение кожи.


Purac FCC является сильной альфа-гидроксикислотой и, следовательно, обладает превосходными отшелушивающими свойствами, хотя они слабее, но уступают гликолевой кислоте.
Продукты AHA должны быть самостоятельным лечебным продуктом и не входить в состав другого продукта.


Purac FCC — это компонент против морщин и пигментации, доступный как в безрецептурных, так и в профессиональных средствах по уходу за кожей.
Purac FCC получают из молока и относятся к классу антивозрастных соединений альфа-гидроксикислот (AHA).
Гликолевая кислота и лимонная кислота являются еще двумя примерами AHA.


Purac FCC представляет собой жидкий раствор в воде чистотой около 80%.
Purac FCC — это AHA.
Purac FCC достаточно добавить несколько капель в 100 мл шампуня, чтобы отрегулировать pH.


Даже в качестве увлажняющей добавки Purac FCC не следует применять более 0,5%.
Перед использованием разбавьте Purac FCC.
Как и все кислоты, Purac FCC важен для того, чтобы ваша кожа привыкла к их использованию.


Purac FCC, также известный как молочная кислота, представляет собой химическое соединение, которое играет роль в нескольких биохимических процессах.
Purac FCC — это альфа-гидроксикислота, получаемая из молока.
В результате относительно большей молекулярной массы кератолитическое действие Purac FCC более мягкое, чем у гликолевой кислоты, что предотвращает раздражение кожи.


Purac FCC выпускается как в виде R (D-), так и S (L+)-энантиомеров, которые можно производить индивидуально до почти идеальной оптической чистоты.
Это означает, что Purac FCC отлично подходит для производства других продуктов, требующих определенной стереохимии.
Purac FCC представляет собой жидкий раствор в воде чистотой около 80%.


Как и во всех производственных процессах, мы рекомендуем провести лабораторные испытания для определения соответствующих количеств.
Обычно Purac FCC титруют разбавленным раствором молочной кислоты (10 или 20% в воде) до достижения желаемого pH.
Purac FCC предпочтителен в качестве подкислителя, поскольку он оказывает меньшее дестабилизирующее воздействие на эмульсии, чем лимонная кислота.


Purac FCC имеет мягкий кисловатый вкус и широко используется в качестве подкислителя в пищевой промышленности.
Purac FCC — это молочная кислота, получаемая естественным путем путем ферментации сахара.
Благодаря своему мягкому кислому вкусу Purac FCC быстро становится предпочтительным подкислителем для напитков.


Purac FCC — это натуральная L-молочная кислота, получаемая путем ферментации сахара.
Purac FCC имеет мягкий кисловатый вкус и широко используется в пищевой промышленности в качестве подкислителя.
Основная цель Purac FCC — сохранить вкус и внешний вид продукта.


Purac FCC действует как увлажняющий агент, используемый во многих продуктах по уходу за кожей.
Purac FCC имеет мягкий кисловатый вкус и наименьший потенциал раздражения.



ИСПОЛЬЗОВАНИЕ и ПРИМЕНЕНИЕ PURAC FCC:
Фармацевтическая технология использует Purac FCC для преобразования водонерастворимых лекарственных веществ в соли молочной кислоты (лактаты); они более растворимы в воде (пример: ципрофлоксацин).
В косметике Purac FCC используется в кремах для кожи и других продуктах для лечения прыщей.


Purac FCC используется для производства кисломолочных продуктов, в качестве пищевого консерванта и для производства химикатов.
Purac FCC играет роль метаболита Daphnia magna и метаболита водорослей.
Purac FCC функционально связан с пропионовой кислотой.


Purac FCC представляет собой кислоту, сопряженную с лактатом.
Нормальный промежуточный продукт ферментации (окисления, метаболизма) сахара.
Концентрированная форма используется внутрь для предотвращения желудочно-кишечной ферментации.


Лактат натрия представляет собой натриевую соль Purac FCC и имеет мягкий солевой вкус.
Его получают путем ферментации источника сахара, такого как кукуруза или свекла, а затем путем нейтрализации полученного Purac FCC с образованием соединения формулы NaC3H5O3.
Purac FCC был одним из активных ингредиентов Phexxi, негормонального противозачаточного средства.


В результате происходит мягкое, но эффективное отшелушивание рогового слоя и одновременная регенерация клеток.
Purac FCC стимулирует выработку коллагена и гликозаминогликанов, составляющих межклеточный материал.
Еще одним преимуществом Purac FCC является то, что он естественным образом увлажняет кожу; это действие приводит к увеличению образования церамидов, тем самым улучшая функцию кератинового барьера.


В секторе средств личной гигиены Purac FCC действует как подкислитель с увлажняющими, отшелушивающими и антибактериальными свойствами.
При местном использовании Purac FCC может помочь в удалении омертвевших клеток кожи, помогая обновить кожу, улучшить текстуру и тон кожи, а также действовать как увлажнитель.


Казеин в ферментированном молоке коагулируется (свертывается) с помощью Purac FCC.
Purac FCC производится естественным путем в результате лакто-ферментации пищевых продуктов.
Некоторыми примерами этих типов продуктов являются кимчи, квашеная капуста, кислое пиво, цукемоно, суан-кай, атсара и йогурт.


Purac FCC используется непосредственно в качестве подкислителя.
Применение Purac FCC в маринованных овощах: Purac FCC эффективно предотвращает порчу оливок, корнишонов, жемчужного лука и других овощей, консервированных в рассоле.


Purac FCC является важным ингредиентом Рикотты Импастата, Моцареллы, Кесо Бланко и других фирменных сыров и может использоваться при производстве кисломолочных продуктов, таких как кумыс, лабан, кефир, а также некоторых творогов.
Purac FCC представляет собой альфа-гидроксикислоту (AHA) и может использоваться для ускорения шелушения и обновления клеток.


Purac FCC можно использовать для регулирования pH многих составов и как более мягкую альтернативу гликолевой кислоте.
Purac FCC и его соль лактат натрия можно использовать в качестве увлажнителей.
Purac FCC используется в продуктах для лица, а также в лосьонах и увлажняющих кремах для тела, но никогда не наносится непосредственно на кожу.


Purac FCC также используется в качестве подкислителя.
Purac FCC является пищевым и используется для производства нескольких видов сыров.
Purac FCC особенно полезен, когда в качестве исходных материалов используются ультрапастеризованное, ультрапастеризованное или сухое молоко, поскольку термическая обработка, используемая при производстве этого молока, дезактивирует лактозу и не позволяет сырной культуре полностью превратить ее в Purac FCC. .


Использование Purac FCC в кондитерских изделиях: например, в карамели, фруктовые жевательные резинки с Purac FCC приводят к мягкому кислому вкусу, улучшению качества и увеличению срока хранения.
Purac FCC обладает увлажняющим эффектом благодаря своему свойству связывать воду в верхних слоях эпидермиса.


Purac FCC используется для производства кисломолочных продуктов, в качестве пищевого консерванта и для производства химикатов.
Purac FCC используется в качестве растворителя и подкислителя при производстве пищевых продуктов, лекарств и красителей.
Purac FCC также используется в качестве протравы при печати на шерстяных изделиях, флюса для пайки, средства для удаления волос и катализатора для фенольных смол.


При производстве обычно добавляют Purac FCC, чтобы pH молока достигал около 5,0.
Казеин в ферментированном молоке коагулируется (свертывается) с помощью Purac FCC, и он также отвечает за кислый вкус хлеба на закваске.
Purac FCC в основном используется для регулирования pH косметических средств и добавляется при производстве шампуней для усиления блеска волос.


Purac FCC легко использовать в жидкой форме.
Purac FCC хорошо сочетается с гиалуроновой кислотой и витаминами A, B и C.
Purac FCC также можно использовать в качестве регулятора pH: Purac FCC снижает pH.


Purac FCC используется в мыловарении. Регулировка pH, повышенная твердость брусков и продуктов твердого формата (особенно, если они предварительно нейтрализованы щелочью).
Purac FCC используется для производства серийной продукции или широко используется в пищевой, винтажной, алкогольной, фармацевтической, полимеризационной, текстильной, кожевенной, табачной, кормовой, пластмассовой химической промышленности, пестицидах, полимерных растворах и других отраслях промышленности.


Purac FCC также рекомендуется для ухода за телом и кожей головы, поскольку помогает при сухости кожи, а также при шелушении и ороговении кожи.
Purac FCC десятилетиями использовался в производстве пива, придавая этому популярному напитку уникальную терпкость.
Благодаря концентрации Purac FCC 80% этот специально разработанный раствор позволяет легко контролировать уровень терпкости вашего продукта.


Независимо от того, используете ли вы Purac FCC для регулировки вкуса пива или для других нужд производства продуктов питания, Purac FCC — идеальный выбор для создания готового продукта, который соответствует всем стандартам качества и одновременно радует потребителей.
Purac FCC можно использовать для регулирования pH многих составов и как более мягкую альтернативу гликолевой кислоте.


Purac FCC используется для регулирования pH косметических продуктов.
При изготовлении шампуней добавляется Purac FCC для придания волосам блеска.
Purac FCC, часто используемый в качестве пищевой или кормовой добавки, может улучшить вкус пищевых продуктов и продлить срок их хранения.


Purac FCC широко используется в консервной, хлебной, мукомольной, кондитерской, кормовой и других отраслях промышленности в качестве улучшителя пищевого вкуса.
Purac FCC особенно подходит для регулирования кислотности различных твердых и порошкообразных пищевых продуктов.
Превосходная функция регулировки pH и антибактериальная способность Purac FCC могут эффективно подавлять рост микроорганизмов и продлевать срок хранения пищевых продуктов.


Используется Purac FCC. Уход за кожей (уход за лицом, чистка лица, уход за телом, уход за ребенком). Уход за волосами (шампуни, кондиционеры и средства для укладки).
Purac FCC — это натуральная L-молочная кислота, получаемая путем ферментации сахара.
Purac FCC имеет мягкий кисловатый вкус и широко используется в качестве подкислителя в пищевой промышленности.


Purac FCC имеет мягкий кисловатый вкус и широко используется в качестве подкислителя в пищевой промышленности.
Purac FCC естественным образом присутствует в волосах, придает им блестящий, привлекательный вид и используется в качестве регулятора pH во всех видах средств по уходу за волосами.
В продуктах против прыщей Purac FCC используется из-за его про��ивомикробного действия.


Косметику с Purac FCC следует использовать с особой осторожностью при сухой коже.
Purac FCC регулирует регенерацию клеток кожи, улучшает структуру и цвет кожи.
Purac FCC усиливает действие других косметических препаратов.


Purac FCC улучшает увлажнение кожи, кожа становится более мягкой и эластичной.
Purac FCC влияет на выработку коллагена кожи, увеличивая толщину и укрепляя дерму.
Purac FCC повышает уровень гликозаминогликанов — соединений, которые впитывают воду, как губка, и обеспечивают увлажнение более глубоких слоев кожи.


Purac FCC классифицируется как передовой ингредиент для ухода за кожей, и его не следует использовать, если вы не разбираетесь в использовании и применении молочной кислоты.
Purac FCC используется для лечения прыщей и пилинга кожи, в пчеловодстве, в производстве продуктов питания, для продления срока хранения мяса, рыбы и птицы, в качестве регулятора кислотности в напитках, в молочных продуктах, выпечке, моющих средствах, добавках к питанию животных и в общей промышленности.


Purac FCC широко используется в пищевой промышленности в качестве подкислителя, а также для консервирования и ароматизации.
Purac FCC очень полезен для омоложения кожи, стимулируя отшелушивание старых поверхностных клеток кожи.
Purac FCC может уменьшить появление тонких линий, неравномерной пигментации, возрастных пятен и уменьшить расширенные поры.


Purac FCC и его соль лактат натрия можно использовать в качестве увлажнителей.
Purac FCC используется для ухода за кожей для регулирования pH, увлажнения, осветления кожи, шелушения, отшелушивания.
Purac FCC используется для ухода за волосами, регулирования pH и влажности.


Purac FCC обладает противомикробным действием и является основой для консервирования путем ферментации многих пищевых продуктов.
Purac FCC служит консервантом, регулятором pH и ароматизатором.
Purac FCC в основном содержится в кисломолочных продуктах, таких как: кумыс, лебан, йогурт, кефир и некоторые твороги.


Более быстрое отшелушивание клеток приводит к росту новых.
Препараты с Purac FCC способствуют лечению прыщей.
При точечном использовании масок с Purac FCC (7,0-15,0%) можно попробовать удалить солнечные, прыщи и стареющие пятна.


После применения препаратов с Purac FCC следует защищать кожу от солнечных лучей.
Без слоев ороговевших клеток «молодой» эпидермис значительно лучше впитывает питательную косметику.
Поэтому тоники, скрабы и маски с Purac FCC относятся к базовой косметике по уходу за жирной, смешанной, акне и зрелой кожей.


Наиболее быстро растущим применением Purac FCC является его использование в качестве мономера для производства полимолочной кислоты или полилактида (PLA).
Применения PLA включают контейнеры для пищевой промышленности и производства напитков, пленки и жесткие контейнеры для упаковки, а также посуду для обслуживания (чашки, тарелки, посуда).


Полимер PLA также можно формовать в волокна и использовать в одежде, волокнистом наполнителе (подушки, одеяла), коврах и нетканых материалах, таких как салфетки.
Purac FCC применяется в красильных ваннах, в качестве протравы при печати шерстяных изделий, растворителя для нерастворимых в воде красок (индулина, спирторастворимого, нигрозина, спиртовой синьки).


Purac FCC часто используется в кремах и лосьонах в более низкой концентрации для более мягкого кислотного пилинга.
Purac FCC используется в косметике и биолифтинге, поскольку делает кожу эластичной, разглаживает морщины, осветляет пигментные пятна и сужает поры.
Purac FCC также используется в кондиционерах и шампунях, поскольку он активирует волосяные луковицы, ускоряя рост волос.


Сочетание мягкого пилинга, регенерации и увлажнения, которое предлагает Purac FCC, делает его идеальным пилингом для чувствительной и обезвоженной кожи, а также хорошим выбором для кожи, которая впервые подвергается химическому пилингу.
Purac FCC в сочетании с pH приводит к целенаправленным действиям и показаниям.


Purac FCC применяется для регулирования pH косметических продуктов, таких как шампуни и гели для душа, кремы и лосьоны.
Как видно из названия, Purac FCC снижает pH продукта.
В дополнение к регуляции pH Purac FCC обладает отличным увлажняющим действием.


Исключением является применение химических пилингов.
Purac FCC широко используется в различных пищевых, промышленных и производственных процессах.
Purac FCC можно использовать для регулирования pH затора или промывной воды.


Purac FCC может иметь цвет от прозрачного до бледно-желтого.
Для контроля pH используется Purac FCC с помощью pH-метра или тест-полосок.
Purac FCC также можно использовать в готовом пиве или вине для придания кислотности.


Purac FCC используется для лечения сухой, грубой и шелушащейся кожи.
Purac FCC также можно использовать при других заболеваниях, определенных врачом.
Обычно Purac FCC титруют разбавленным раствором молочной кислоты (10 или 20% в воде) до достижения желаемого pH.


Purac FCC используется для восстановления хроматов при протравливании шерсти.
Purac FCC используется при производстве сыров, кондитерских изделий.
Purac FCC используется в составе детских молочных смесей; подкислитель в напитках; для подкисления сусла в пивоварении.


Purac FCC — это натуральная L-молочная кислота, получаемая путем ферментации сахара.
Purac FCC имеет мягкий кисловатый вкус и широко используется в качестве подкислителя в пищевой промышленности.
Основная функция Purac FCC — сохранение вкуса.


Аналогичным образом, Purac FCC используется при лактоферментации и консервировании силоса при производстве кормов.
В технических применениях Purac FCC обеспечивает поддержку благодаря своему биоцидному эффекту и поэтому является компонентом дезинфицирующих растворов и других чистящих средств.
Кроме того, Purac FCC используется для щадящей декальцинации.


Предпочтителен в качестве подкислителя, поскольку Purac FCC имеет меньшее дестабилизирующее воздействие на эмульсии, чем лимонная кислота.
Purac FCC используется для лечения сухой, грубой и шелушащейся кожи.
Purac FCC также можно использовать при других заболеваниях, определенных врачом.


Purac FCC — одна из популярных пищевых добавок и ингредиентов в большинстве стран.
Обычно Purac FCC используется в качестве консерванта и антиоксиданта.
Purac FCC также используется в качестве присадки к топливу, химического промежуточного продукта, регулятора кислотности и дезинфицирующего средства.


Purac FCC также используется в растворах для диализа, что приводит к более низкой частоте побочных эффектов по сравнению с ацетатом натрия, который также можно использовать.
Purac FCC часто используется в косметической промышленности из-за эффекта стимулирования выработки коллагена, помогая укрепить кожу, предотвращая появление морщин и провисание.


Purac FCC используется в качестве добавки в кормах для животных.
Purac FCC обладает свойствами, способствующими укреплению здоровья.
Purac FCC используется в качестве увлажнителя или увлажняющего крема в некоторых косметических средствах.


Purac FCC используется в качестве протравы, химического вещества, которое помогает тканям впитывать красители в текстиле.
Purac FCC также используется при дублении кожи.
Purac FCC используется при производстве лаков и чернил.


Purac FCC является пищевым и используется для производства нескольких видов сыров.
Purac FCC особенно полезен, когда в качестве исходных материалов используются ультрапастеризованное, ультрапастеризованное или сухое молоко, поскольку термическая обработка, используемая при производстве этого молока, дезактивирует лактозу и не позволяет сырной культуре полностью превратить ее в Purac FCC. .


Включение дополнительного количества Purac FCC перед сычужным ферментом устраняет этот недостаток и повышает выход творога.
Purac FCC является важным ингредиентом Рикотты Импастата, Моцареллы, Кесо Бланко и других фирменных сыров и может использоваться при производстве кисломолочных продуктов, таких как кумыс, лабан, кефир, а также некоторых творогов.


Purac FCC является основным строительным блоком полимолочной кислоты (PLA).
PLA — это биоразлагаемый полимер, который можно использовать для производства возобновляемых и компостируемых пластмасс.
Purac FCC используется для регулирования pH затора или промывной воды.


Purac FCC используется в лагерах типа Pilsner для снижения щелочности.
Purac FCC используется для снижения щелочности без добавления ионов сульфата и хлорида.
Purac FCC также можно использовать для незначительных корректировок пивоварения.


Purac FCC также может вызывать микропилинг, который помогает уменьшить различные шрамы и пигментные пятна.
Это отличное решение для людей с чувствительной или сухой кожей, на которую отшелушивающие средства не действуют.
Purac FCC используется для лечения сухой, грубой и шелушащейся кожи.


Purac FCC также можно использовать при других заболеваниях, определенных врачом.
Перед использованием разбавьт�� Purac FCC.
Как и все кислоты, Purac FCC важен для того, чтобы ваша кожа привыкла к их использованию.


У тех, чья кожа не привыкла к кислотам, может возникнуть легкое жжение и покраснение.
Если это произойдет, Purac FCC сократит использование.
Purac FCC содержит альфа-гидроксикислоту (AHA), которая может повысить чувствительность вашей кожи к солнцу и, в частности, вероятность солнечных ожогов.


Purac FCC используйте солнцезащитный крем, носите защитную одежду и ограничьте пребывание на солнце во время использования этого продукта и в течение недели после него.
Purac FCC снижает уровень щелочности пивоваренного раствора, стимулируя максимальную активность ферментов в сусле, обеспечивая оптимальный уровень pH на протяжении всего процесса пивоварения.


Purac FCC используется в качестве ценного компонента в биоматериалах.
Purac FCC используется в качестве натурального антибактериального средства при дезинфекции продуктов.
Purac FCC используется в промышленных процессах.


PH можно использовать на более высоких уровнях для сквашивания пива.
Purac FCC оказывает хорошее увлажняющее действие на кожу и может использоваться в сыворотках, гелях, тониках, кремах и лосьонах на водной основе.
Purac FCC может помочь коже выглядеть свежее и моложе.


Purac FCC особенно полезен в ночных кремах и антивозрастных продуктах.
Когда Purac FCC используется в более высоких концентрациях, он может оказывать отшелушивающее действие.
Purac FCC улучшит внешний вид кожи и поможет удалить поверхностный мусор и омертвевшие клетки кожи.


Уход за волосами: Purac FCC, использованный в упаковке для волос, очистит перегруженную кожу головы, например, после снятия плетения, которое использовалось в течение нескольких месяцев.
Никогда не наносите Purac FCC непосредственно на кожу.


Best Purac FCC добавляется на этапе 3 (остывания) при приготовлении кремов и лосьонов.
Имейте в виду, что Purac FCC может сделать кремы и лосьоны более жидкими или нестабильными, поэтому вам нужно начинать с очень сильного и стабильного крема или лосьона.
В качестве регулятора pH Purac FCC можно использовать для снижения значения pH (более кислого) при использовании консерванта K, который правильно действует только в узком диапазоне pH.


Часто Purac FCC получают из молока, однако наш продукт изготовлен из кукурузы или кукурузы и не содержит ГМО.
Purac FCC продается в концентрации 80%, т.е. Purac FCC с 20% воды в виде водного раствора.
Согласно базе данных косметических ингредиентов (CosIng), Purac FCC выполняет следующие функции: буферизация, увлажнение, кондиционирование кожи.


Purac FCC повышает выход экстракта и способность к ферментации
Purac FCC подходит для пива, в котором не требуются другие анионы, например, для лагеров.
Purac FCC улучшает прозрачность и стабильность готового продукта.


Концентрация Purac FCC для химического отшелушивания, подходит для всех типов кожи.
Purac FCC обеспечивает регенерацию клеток, увлажнение и уменьшение морщин на коже.
Типичный уровень использования Purac FCC составляет от 1 до 20% в пилингах, кремах, лосьонах, масках, очищающих средствах.


Из-за кислотности Purac FCC конечный продукт необходимо проверить на безопасный уровень pH.
Оптимальный диапазон pH Purac FCC составляет 3,5-5,0.
Некоторые безрецептурные продукты после добавления Purac FCC расслаиваются из-за низкого pH и требуют стабилизации.


Во многих пищевых продуктах Purac FCC обычно используется либо в качестве регулятора pH, либо в качестве консерванта, либо в качестве ароматизатора.
Purac FCC используется в качестве регулятора кислотности.
Purac FCC эффективно предотвращает порчу овощей.


Purac FCC часто используется в качестве более мягкой альтернативы гликолевой кислоте в косметических рецептурах, а также может использоваться для снижения pH во время производства.
Purac FCC производится путем ферментации глюкозного сиропа из кукурузы с использованием бактериального штамма.
Purac FCC представляет собой кислоту и никогда не должен использоваться в неразбавленном виде.


При использовании в соответствующих концентрациях (до 5,0%) Purac FCC разрыхляет межклеточный цемент.
Регулярное использование косметики с Purac FCC омолаживает эпидермис и разглаживает морщины за счет постепенного отшелушивания омертвевших клеток рогового слоя.


Purac FCC разглаживает мелкие поверхностные морщины, повышает эластичность и упругость кожи; это антивозрастной ингредиент; помогает в случае обесцвечивания и небольших шрамов от прыщей.
Purac FCC очищает поры и проявляет антибактериальные свойства, следовательно, предотвращает образование проблемных мест, таких как экземы всех видов и черные точки; помогает при лечении прыщей.


Purac FCC используется в мыловарении для регулирования pH, повышения твердости брусков и продуктов твердого формата (особенно если они предварительно нейтрализованы щелочью).
Purac FCC используется для ухода за кожей. Регулировка pH, увлажнение, осветление кожи, шелушение, отшелушивание.
Purac FCC используется для ухода за волосами. Регулировка pH, влажность.


Уход за кожей: В зависимости от степени разведения Purac FCC можно использовать в качестве регулятора pH, увлажняющего крема или в качестве пилинга для кожи.
В более низких процентных количествах Purac FCC снижает трансэпидермальную потерю воды (TEWL), поддерживая барьерную функцию кожи.
При нанесении Purac FCC расщепляет связи между кератиноцитами внешнего слоя, тем самым сокращая их и приводя к постепенной регенерации.


Purac FCC также используется при дублении кожи, кислотной обработке нефтяных скважин и в качестве регулятора роста растений.
Purac FCC применяется в нефтедобыче и нефтепереработке, пайке, сельском хозяйстве (пестициды), дублении и обработке кожи, выделке и крашении меха, текстиле (печать, крашение или отделка).


Purac FCC используется в качестве превосходного подкислителя для многих молочных продуктов.
Purac FCC используется для усиления пикантного вкуса.
В фармацевтической технологии Purac FCC используется в качестве исходного материала для других веществ.


Purac FCC используется при приготовлении инъекций лактата натрия. Ингредиент косметики.
Purac FCC используется в качестве компонента сперматоцидных желе.
Purac FCC используется для удаления Clostridium Butyricum при производстве дрожжей; удаление волос, пухлость и декальцинирование шкур.


Purac FCC используется в качестве растворителя формиата целлюлозы.
Purac FCC используется для мягких припоев.
Purac FCC используется при производстве лактатов, которые используются в пищевых продуктах, в медицине и в качестве растворителей.


Purac FCC используется как пластификатор, катализатор при литье фенолальдегидных смол.
Purac FCC можно использовать в качестве подкислителя, ароматизатора и регулятора pH в напитках, мясе, заквасках, салатах и заправках, кондитерских изделиях и маринованных овощах.


Purac FCC используется в пищевой и технической промышленности.
Жидкий Purac FCC, представляющий собой смесь левовращающей и правовращающей молочной кислоты в соотношении 1:1, очень часто используется для регулирования кислотности в хлебобулочных и кондитерских изделиях или напитках, а также для консервирования.


-Использование материалов Purac FCC:
Purac FCC — это мономер полилактидов или полимолочных кислот (PLA), которые различными способами используются в качестве биоразлагаемых пластиков и пластиков на биологической основе.
Purac FCC обладает антибактериальным эффектом и поэтому добавляется в жидкое мыло, чистящие и моющие средства.

Они оптимально проявляют свой дезинфицирующий эффект при значении pH от 3 до 4.
Purac FCC использовался и также используется в качестве противозачаточного средства.
Purac FCC используется в качестве средства для удаления накипи на кожевенных заводах при удалении накипи из шкур.

Purac FCC также используется для этой цели в текстильной промышленности и полиграфических компаниях.
Некоторые чистящие таблетки для кофемашин, автоматов по производству безалкогольных напитков и аналогичных приборов содержат Purac FCC в качестве средства для удаления накипи.
Пчеловоды используют Purac FCC для обработки пчел от клеща Варроа, гарантируя, что обработанные ульи или соты не содержат расплода.
Арахнологи используют Purac FCC для освещения подготовленной эпигинии самок пауков или других хитиновых структур, а также для растворения остатков тканей.


- Использование Purac FCC в пивоварении:
Purac FCC призван снизить уровень pH и добавить немного терпкости.
Естественно добавляйте в небольших количествах, иначе Purac FCC станет сильно кислым.


-При изготовлении сыра и взбитом масле использование Purac FCC:
В частности, рикотта и взбитое масло в сочетании с ГДЛ.
Рикотта Импастата, Моцарелла и Кесо Бланко.


-Интересное непищевое применение Purac FCC:
Purac FCC является основным строительным блоком для биоразлагаемых пластиков на основе полимолочной кислоты (PLA).
PLA — это биоразлагаемый полимер, который можно использовать для производства возобновляемых и компост��руемых пластмасс.
Purac FCC также используется в косметической промышленности для лечения прыщей.


-Использование источника питания Purac FCC:
Ряд продуктов производится непосредственно посредством ферментации Purac FCC.
В основном это кисломолочные продукты, такие как простокваша, йогурт, кефир и пахта.
Их получают путем заражения пастеризованного молока заквасочными культурами бактерий Purac FCC.

Другие продукты включают лакто-ферментированные овощи, такие как квашеная капуста, свекла в некоторых сортах борща или кимчи, а также закваска и продукты на закваске.
Силос, свежий корм, полученный путем ферментации, также производится на основе ферментации Purac FCC.
В качестве пищевой добавки Purac FCC имеет обозначение E 270.

Purac FCC используется по-разному в качестве регулятора кислотности в пищевой промышленности и производстве предметов роскоши, например, в хлебобулочных изделиях, кондитерских изделиях и иногда в лимонадах.
Изменяя значение pH в пище до pH около 4, пища сохраняется, поскольку в значительной степени исключается колонизация другими микроорганизмами.
Для обогащения кальцием также можно добавлять в виде солей лактат кальция или глюконат лактата кальция Purac FCC.



ПРЕТЕНЗИИ PURAC FCC:
*Анти-акне Агенты
*Противомикробные препараты
*Увлажняющие агенты



ФУНКЦИИ PURAC FCC:
*В пищевых продуктах, помимо своей питательной функции для нормального роста, Purac FCC улучшает вкус и аромат, улучшает качество пищевых продуктов и напитков, таких как кондитерские изделия, торты, сухое молоко, йогурт и т. д., в качестве укрепляющего агента, буферного агента и регулятора муки.
*Purac FCC повышает эффективность антиоксидантов, предотвращает обесцвечивание фруктов и овощей.



ОСОБЕННОСТИ И ПРЕИМУЩЕСТВА PURAC FCC:
*Purac FCC очень полезен для омоложения кожи, стимулируя отшелушивание старых поверхностных клеток кожи.
*Purac FCC может уменьшить появление тонких линий, неравномерной пигментации, возрастных пятен и уменьшить расширенные поры.
*Purac FCC используется для тех, кто впервые делает пилинг, или для людей с чувствительной кожей.
*Purac FCC часто используется в кремах и лосьонах в более низкой концентрации для более мягкого кислотного пилинга.



ИСПОЛЬЗОВАНИЕ В ПИЩЕВОЙ ПРОДУКЦИИ, PURAC FCC:
Purac FCC — это натуральный консервант, который содержится в некоторых продуктах питания, включая маринованные овощи, йогурт и выпечку.
Purac FCC — дешевый и минимально перерабатываемый материал.
Культуры Lactobacillus и Streptococcus производят Purac FCC посредством ферментации.
Бактерии расщепляют сахар, чтобы извлечь энергию и произвести Purac FCC в качестве побочного продукта.
Purac FCC помогает регулировать уровень pH и предотвращает рост микроорганизмов, продлевая срок хранения.



КАК ИСПОЛЬЗОВАТЬ PURAC FCC В КОСМЕТИКЕ:
- Purac FCC — продукт, который нельзя наносить на чистую кожу.
- Purac FCC может быть включен в качестве ингредиента в косметические композиции, содержащие подкислители и воду: сыворотки, гели, тоники, маски, лосьоны, кремы, шампуни, очищающие средства и т. д.



ПРЕИМУЩЕСТВА И ПРИМЕНЕНИЕ PURAC FCC:
Purac FCC используется для лечения гиперпигментации, пигментных пятен и других состояний, которые способствуют тусклому и неровному цвету лица.
Purac FCC также улучшает тон кожи и сужает поры.

Purac FCC способствует обновлению и обновлению клеток — процессам, в ходе которых ваша кожа теряет старые клетки и заменяет их новыми.
Purac FCC очень хорошо подходит для чувствительной кожи из-за его более мягкого действия по сравнению с другими альфа-гидроксикислотами.

Purac FCC также является ключевым компонентом продаваемых без рецепта лосьонов и кремов для «куриной кожи», то есть прыщей на тыльной стороне рук.
Purac FCC способствует растворению закупорок клеток кожи, которые образуются вокруг волосяного фолликула, сглаживая неровности.
Purac FCC обычно используется в средствах местного применения при экземе, псориазе и розацеа.



СВОЙСТВА PURAC FCC:
Свойства Purac FCC
- Кератолитик отшелушивает кожу, удаляя омертвевшие клетки кожи и кожи головы.
- Стимулирует синтез коллагена и эластина, способствуя обновлению клеток.
- Purac FCC улучшает текстуру кожи и внешний вид pH.
- Активирует эмульгатор-кондиционер, используемый при производстве составов по уходу за волосами.



ПРЕИМУЩЕСТВА PURAC FCC:
*Осветляет тусклый цвет лица.
*Увлажнитель и более упругая кожа
* Эксфолиант
*Улучшает тон и текстуру кожи.
*Подходит для веганов
*Без ГМО



ФУНКЦИЯ PURAC FCC:
В пищевых продуктах, помимо своей питательной функции для нормального роста, Purac FCC улучшает вкус и аромат, улучшает качество пищевых продуктов и напитков, таких как кондитерские изделия, торты, сухое молоко, йогурт и т. д., в качестве укрепляющего агента, буферного агента и регулятора муки.
Purac FCC повышает эффективность антиоксидантов, предотвращает обесцвечивание фруктов и овощей.



ПРЕИМУЩЕСТВА PURAC FCC:
Purac FCC снижает уровень щелочности пивоваренного раствора, стимулируя максимальную активность ферментов в сусле, обеспечивая оптимальный уровень pH на протяжении всего процесса пивоварения.
Purac FCC улучшает выход экстракта и ферментируемость.
Purac FCC подходит для пива, в котором не требуются другие анионы, например, для пильзенских лагеров.
Purac FCC также можно использовать для снижения pH конечного сусла или продуктов.



РЕКОМЕНДУЕМЫЕ СМЕСИ PURAC FCC:
Purac FCC хорошо работает в сочетании с витаминами A, B и C.
Обязательно проверяйте конечный уровень pH не ниже 3,5 при объединении нескольких кислых ингредиентов вместе.



КАК РАБОТАЕТ PURAC FCC:
Purac FCC работает путем удаления верхнего слоя клеток кожи, который обычно состоит из омертвевших клеток кожи.
Purac FCC также увеличивает естественную способность кожи удерживать влагу, придавая ей увлажненный вид.



КОНЦЕНТРАЦИЯ И РАСТВОРИМОСТЬ PURAC FCC:
Purac FCC рекомендуется использовать в концентрации 1–5%.
Purac FCC растворим в воде, спирте и глицерине, но нерастворим в масле.



КАК ИСПОЛЬЗОВАТЬ PURAC FCC:
Подготовьте масляную и водную фазы вашего состава отдельно.
Нагрейте масляную и водную фазы, используя пароварку.
Добавьте Purac FCC к водной фазе, постоянно перемешивая.
Смешайте обе фазы вместе с помощью мини-миксера или большой кисточки для смешивания.



ФИЗИЧЕСКИЕ И ХИМИЧЕСКИЕ СВОЙСТВА PURAC FCC:
Конечное использование: Пищевая добавка
Цвет: желтый, прозрачный, бесцветный
Запах: Характерный
pH: < 1,2 при 25 °C (77 °F)
Точка кипения: 120–130 °C (248–266 °F).
Температура вспышки: Не применимо
Температура самовоспламенения: > 400 °C (> 752 °F)
Вязкость, динамическая: 5–60 мПа•с при 25 °C (77 °F)
Поставщик: Purac America Inc.
КАС: 79-33-4
Применение: ароматизаторы, добавки-консерванты.
Химическая форма: Жидкость
Продукт: L-молочная кислота
Форма: жидкость
Сорт: съедобный специальный

Цвет: свежий макс. 50 афа
Цвет, 6 месяцев, макс. 25°C. 50 афа
Запах: приятный
Стереохимическая чистота (L-изомер): мин. 95%
Анализ: 87,5-88,5% мас./мас.
Плотность: при 20°С 1,20-1,22 г/мл.
Сульфатная зола макс.: 0,1%
Общее содержание тяжелых металлов макс.: 10 ppm
Железо макс.: 10 частей на миллион
Мышьяк макс.: 1 ppm
Кальций макс.: 20 ppm
Хлорид макс.: 10 ppm
Сульфат макс.: 20 ppm
Снижение уровня сахара: проходит тест FCC
Молекулярная формула: CH3CHOHCOOH.
Молекулярный вес: 90
Химическое название: 2-гидроксипропионовая кислота.

Запах: без запаха
Точка плавления/точка замерзания:
Температура плавления: 18 °C при 1,013 гПа.
Начальная точка кипения и диапазон кипения: 122 °C при 18,66–19,99 гПа.
Горючесть (твердого тела, газа): Данные отсутствуют.
Верхний/нижний пределы воспламеняемости или взрывоопасности: данные отсутствуют.
Температура вспышки: 113 °C – в закрытом тигле.
Температура самовоспламенения: 400 °С при 1,011,4 – 1,018,9 гПа.
Температура разложения: Данные отсутствуют.
pH: данные отсутствуют
Вязкость
Вязкость, кинематическая: Нет данных.
Вязкость, динамическая: данные отсутствуют.
Растворимость в воде: 100 г/л при 20 °C – растворим.

Коэффициент распределения: н-октанол/вода:
log Pow: около -0,54 при 25 °C - Биоаккумуляции не ожидается.
Давление пара: данные отсутствуют.
Плотность: 1,25 г/см3 при 15 °C
Относительная плотность: данные отсутствуют.
Относительная плотность пара: данные отсутствуют.
Характеристики частиц: данные отсутствуют.
Взрывоопасные свойства: данные отсутствуют.
Окислительные свойства: нет
Другая информация по безопасности:
Поверхностное натяжение 70,7 мН/м при 1 г/л при 20 °C.
Формула: H₃CCH(OH)COOH
ММ: 90,08 г/моль
Температура кипения: 122 °C (20 гПа)
Плотность: 1,11…1,21 г/см³ (20 °С)
Температура хранения: Окружающая среда
Номер леев: MFCD00004520
Номер CAS: 50-21-5
ЕИНЭКС: 200-018-0

КАС: 50-21-5
МФ: C3H6O3
МВт: 90,08
ЕИНЭКС: 200-018-0
Мол Файл: 50-21-5.mol
Химические свойства молочной кислоты
Температура плавления: 18°C.
альфа: -0,05 º (c = чистая 25 ºC)
Точка кипения: 122 °C/15 мм рт. ст. (лит.)
плотность: 1,209 г/мл при 25 °C (лит.)
плотность пара: 0,62 (по сравнению с во��духом)
давление пара: 19 мм рт.ст. (@ 20°C)
ФЕМА: 2611 | МОЛОЧНАЯ КИСЛОТА
показатель преломления: n20/D 1,4262

Фп: >230 °F
температура хранения: 2-8°C
растворимость: смешивается с водой и этанолом (96 процентов).
форма: сироп
рка: 3,08 (при 100 ℃ )
Удельный вес: 1,209
цвет: от бесцветного до желтого
Растворимость в воде: РАСТВОРИМЫЙ
Мерк: 145 336
Номер JECFA: 930
РН: 1209341
Стабильность: Стабильная.
Физическое состояние: вязкий
Цвет: бесцветный



МЕРЫ ПЕРВОЙ ПОМОЩИ PURAC FCC:
-Описание мер первой помощи:
*При вдыхании:
При вдыхании выведите пострадавшего на свежий воздух.
*При попадании на кожу:
Смыть большим количеством воды с мылом.
*В случае зрительного контакта:
В качестве меры предосторожности промойте глаза водой.
*При проглатывании:
Никогда не давайте ничего перорально человеку, находящемуся без сознания. Прополоскать рот водой.
-Указание на необходимость немедленной медицинской помощи и специального лечения:
Данные недоступны



МЕРЫ ПРИ СЛУЧАЙНОМ ВЫБРОСЕ PURAC FCC:
-Экологические меры предосторожности:
Не допускайте попадания продукта в канализацию.
-Методы и материалы для локализации и очистки:
Хранить в подходящих закрытых контейнерах для утилизации.



МЕРЫ ПОЖАРОТУШЕНИЯ PURAC FCC:
-Средства пожаротушения:
*Подходящие средства пожаротушения:
Используйте водяной спрей, спиртостойкую пену, сухие химикаты или углекислый газ.
-Дальнейшая информация:
Данные недоступны



КОНТРОЛЬ ВОЗДЕЙСТВИЯ/ПЕРСОНАЛЬНАЯ ЗАЩИТА PURAC FCC:
-Параметры управления:
--Ингредиенты с параметрами контроля на рабочем месте:
-Средства контроля воздействия:
--Средства индивидуальной защиты:
*Защита глаз/лица:
Используйте средства защиты глаз.
*Защита кожи:
Работайте в перчатках.
Вымойте и высушите руки.
*Защита тела:
Непроницаемая одежда
*Защита органов дыхания:
Защита органов дыхания не требуется.
-Контроль воздействия на окружающую среду:
Не допускайте попадания продукта в канализацию.



ОБРАЩЕНИЕ И ХРАНЕНИЕ PURAC FCC:
-Условия безопасного хранения, включая любые несовместимости:
*Условия хранения:
Хранить в прохладном месте.
Хранить контейнер плотно закрытым в сухом и хорошо проветриваемом месте.
Открытые контейнеры необходимо тщательно закрыть и хранить в вертикальном положении во избежание утечки.



СТАБИЛЬНОСТЬ И РЕАКЦИОННАЯ СПОСОБНОСТЬ PURAC FCC:
-Реактивность:
Данные недоступны
-Химическая стабильность:
Стабилен при рекомендуемых условиях хранения.
-Возможность опасных реакций:
Данные недоступны
-Условия, чтобы избежать:
Данные недоступны

SYNONYMS Piroctone olamine; Piroctone ethanolamine salt; 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanolammonium salt; Kopirox; Octopirox; CAS NO. 68890-66-4

SYNONYMS Polyaluminum chlorohydrate; PAC; Polyaluminum hydroxychloride; CAS NO. 1327-41-9 (Basic)

4-Methylbenzenesulfonic acid monohydrate; Toluol-4-sulfonsäure; ácido tolueno-4-sulfónico; Acide toluène-4-sulfonique; p-tsa monohydrate; Methylbenzenesulfonic acid monohydrate; PTSA monohydrate; Toluenesulfonic acid monohydrate; Tosic acid monohydrate; cas no : 6192-52-5

PVM/MA COPOLYMER, N° CAS : 9011-16-9, Nom INCI : PVM/MA COPOLYMER. Classification : Polymère de synthèse. Ses fonctions (INCI): Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion. Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Agent de fixation capillaire : Permet de contrôler le style du cheveu. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Noms français : 2,5-FURANDIONE, POLYMER WITH METHOXYETHENE; POLYMERE DU METHOXYETHENE ET DU FURANNE-2,5-DIONE. Noms anglais : MALEIC ANHYDRIDE, POLYMER WITH METHYL VINYL ETHER; METHYL VINYL ETHER-MALEIC ANHYDRIDE POLYMER ; Utilisation et sources d'émission. Fabrication de produits textiles, fabrication de colles ou adhésifs

cas no 9003-39-8 Plasdone; PVP; Polyvidone; Povidone; 1-vinylpyrrolidin-2-one homopolymer; Plasdone K29-32; Polyvinylpyrrolidone K30; Crospovidone;

PVP K 30 PVP K 30 is a film former in hair styling products. PVP is an emulsion stabilizer in creams and lotions. PVP can also be a dispersant for hair colorants. PVP K 30 is available as 100% powder and as 20% aqueous solution. PVP (Polyvinylpyrrolidone) K-30 polymer is a hygroscopic, amorphous polymer. PVP K 30 is a linear nonionic polymer that is soluble in water and organic solvents and is pH stable. PVP K 30 forms hard glossy transparent films and have adhesive and cohesive properties. General description Polyvinylpyrrolidone (PVP), also commercially known as K30, is a water soluble polymer. It has a hygroscopic nature with good adhesive properties. It has a stable pH and has the ability to form transparent films. Application PVP has a wide range of usage such as: • an adhesive for making gluesticks and metal adhesives • a dispersant for ceramics • coatings and inks • formation of synthetic fibres and textiles • porous membranes The PVP K 30 E- and I-series To fit more application areas, the E- and I-series of PVP K 30 copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. Storage and handling of PVP K 30 PVP K 30 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 30 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 30) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. USES PVP K 30 is used in as an adhesive in glue stick and hot-melt adhesives PVP K 30 is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 30 is used in as an emulsifier and disintegrant for solution polymerization PVP K 30 is used in increase resolution in photoresists for cathode ray tubes (CRT) PVP K 30 is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 30 is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 30 is used in as a thickening agent in tooth whitening gels PVP K 30 is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 30 is used in as an additive to Doro's RNA extraction buffer PVP K 30 is used in as a liquid-phase dispersion enhancing agent in DOSY NMR PVP K 30 is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly PVP K 30 is used in as a stabilizing agent in all inorganic solar cells Other uses of PVP K-30 solution PVP K 30 binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. Applications and Usage Notes of PVP K 30 Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks. Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier. Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes. Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates. Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes. Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths. Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives. Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. The PVP K 30 W copolymers PVP K 30 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 30 W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 30 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 30, PVP K 30 E-535 and PVP K 30 E-335. In general, PVP K 30 is less hygroscopic than PVP. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. PVP K-30 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-30 solution is a film former. It is suggested for use in hair styling formualations. PVP K-30 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. PVP K 30 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 30 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP K 30 Copolymer? PVP K 30 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. The advantages of using PVP K 30 copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 30 copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid To fit many application areas, the E and I series of PVP K 30 copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. PVP K 30 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 30 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 30) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 30 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 30 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 30 is a 70/30 copolymer of PVP K 30 and vinyl acetate supplied as a 50% solution in water. PVP K 30 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 30 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Key Attributes of PVP K 30 Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring. High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts. Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone. Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications. Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application. Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 30) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 30 , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 30 acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 30 finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 30 thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 30 used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 30 provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. Uses of PVP K-30 solution Medical uses of PVP K-30 solution PVP K 30 was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 30 is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 30 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 30 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. PVP K 30 is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. PVP K 30 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP K 30 is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 30 is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 30 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 30 is useful for making an aqueous mounting medium. PVP K 30 can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production. Safety of PVP K 30 The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses, and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 30 has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 30 component of the solution. A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP. In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP. Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 30 instead. Properties of PVP K 30 PVP K 30 is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin). When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 30 and its oxidized hydrolyzate. History of PVP K 30 PVP K 30 was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 30 was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 30 copolymer PVP K 30 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. PVP K 30 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 30 W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 30 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 30 E-735 copolymer, PVP K 30 E-535 copolymer and PVP K 30 E- 335 copolymer. In general, PVP K 30 copolymer is less hygroscopic than PVP. PVP K 30 copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 30 copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 30 copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 30 copolymer is used as a binder to allow the aqueous processing of photoresists. PVP K 30 is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene. PVP K 30 is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 30 monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 30 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 30 (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 30 tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 30 Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid.

PVP; Povidone; PVPP; Crospovidone; Polyvidone; PNVP; Poly[1-(2-oxo-1-pyrrolidinyl)ethylen]; 1-Ethenyl-2-pyrrolidon homopolymer; 1-Vinyl-2-pyrrolidinon-Polymere CAS NO: 9003-39-8

PVP K 60 Applications and Usage Notes Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks. Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier. Coatings/lnks – digital printing coating, ball-point inks, water colors for commercial art, temporary protective coatings, paper coatings. Lithography and Photography – foil emulsions, etch coatings, plate storage, gumming of lithographic plates, dampener roll solutions, photo and laser imaging processes. Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths. Paper – inorganic papers, cellulose papers, rag stock, rag stripping, coloring and beating operations, copying paper, printing paper and electric insulating papers, paper adhesives. PVP K 60 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 60) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. Application of PVP K 60 Polyvinylpyrrolidone solution (PVP) is also known as K60 and can be used in a variety of applications such as biomedical, tissue engineering, and medical materials. To fit more application areas, the E- and I-series of PVP K 60 copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. PVP K 60 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 60 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 60 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. PVP K 60 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 60 W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Other uses of PVP K-60 solution PVP K 60 binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 60 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP K 60 is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 60 is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 60 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 60 is useful for making an aqueous mounting medium. PVP K 60 can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production. Safety of PVP K 60 The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses, and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 60 has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 60 component of the solution. A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP. In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP. Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 60 instead. Plasticizers and polymers: Most PVP K 60 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 60, PVP K 60 E-535 and PVP K 60 E-335. In general, PVP K 60 is less hygroscopic than PVP. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Storage and handling of PVP K 60 PVP K 60 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. PVP K-60 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-60 solution is a film former. It is suggested for use in hair styling formualations. PVP K-60 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 60) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 60 , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. The advantages of using PVP K 60 copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 60 copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties Key Attributes of PVP K 60 -Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring. -High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts. -Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone. -Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications. -Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application. -Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes of PVP K 60 -Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks. -Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier. -Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes. -Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates. -Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes. -Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths. -Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives. -Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. PVP K 60 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 60 acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 60 finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 60 thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 60 used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 60 provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 60 is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene. PVP K 60 is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 60 monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 60 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 60 (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 60 tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 60 Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. PVP K 60 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 60) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 60 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 60 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 60 is a 70/30 copolymer of PVP K 60 and vinyl acetate supplied as a 50% solution in water. PVP K 60 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 60 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Uses of PVP K-60 solution Medical uses of PVP K-60 solution PVP K 60 was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 60 is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 60 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 60 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. PVP K 60 is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Properties of PVP K 60 PVP K 60 is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin). When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 60 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 60 E-735 copolymer, PVP K 60 E-535 copolymer and PVP K 60 E- 335 copolymer. In general, PVP K 60 copolymer is less hygroscopic than PVP. USES of PVP K 60 It is used in as an adhesive in glue stick and hot-melt adhesives It is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 60 is used in as an emulsifier and disintegrant for solution polymerization It is used in increase resolution in photoresists for cathode ray tubes (CRT) PVP K 60 is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters It is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating It is used in as a thickening agent in tooth whitening gels PVP K 60 is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation It is used in as an additive to Doro's RNA extraction buffer It is used in as a liquid-phase dispersion enhancing agent in DOSY NMR PVP K 60 is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly PVP K 60 is used in as a stabilizing agent in all inorganic solar cells PVP K 60 copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 60 copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 60 copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 60 copolymer is used as a binder to allow the aqueous processing of photoresists. History of PVP K 60 PVP K 60 was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 60 was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 60 copolymer PVP K 60 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. PVP K 60 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 60 W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution.

PVP K 85 PVP K 85 Solution is a hygroscopic, amorphous polymer supplied as a clear aqueous solution. It can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. This product is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. PVP products are recommended for dishwashing, fabric care, household cleaning, and industrial and institutional cleaning applications. Polyvinylpyrrolidone (PVP K 85). It is in form of aqueous solution. It is linear, random and is produced by the free-radical polymerization. It is hygroscopic and amorphous. It has high polarity, dispersany, adhesion and cohesion. It forms hard, glossy and oxygen permeable film. It is soluble in water and polar solvents. Insoluble in esters, ethers, ketones and hydrocarbons. Suitable for digital ink-jet printing. PVP K 85 100% Powder is soluble in water and many organic solvents and it forms hard, transparent, glossy film. PVP is compatible with most inorganic salts and many resins. PVP stabilizes emulsions, dispersions and suspensions. While PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K 85 100% Powder appears as a white powder. PVP (Polyvinylpyrrolidone) K-85 polymer is a hygroscopic, amorphous polymer. They are linear nonionic polymers that are soluble in water and organic solvents and are pH stable. PVP K 85 forms hard glossy transparent films and have adhesive, cohesive and dispersive properties. Key Attributes of PVP K 85  Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring.  High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.  Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone.  Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable to numerous applications.  Adhesion, taking advantage of the molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.  Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes  Adhesives – pressure-sensitive and water-remoistenable types of adhesives, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks.  Ceramics – binder in high temperature fire prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier.  Glass and Glass Fibers – acts as a binder, lubricant and coating agent.  Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water-colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes.  Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates.  Lithography and Photography – foil emulsions, etch coatings, plate storage, gumming of litho- graphic plates, dampener roll solutions, photo and laser imaging processes, microencapsulation, thermal recording, carrier, finisher preserver of lithographic plates, thermal transfer recording ribbons and optical recording discs.  Fibers and Textiles – synthetic fibers, dyeing and printing, fugitive tinting, dye stripping and dispersant, scouring, delustering, sizing and finishing, greaseproofing aid, soil release agent. Widely used as dye dispersant and to disperse titanium dioxide.  Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes.  Metallurgy – processing for both ferrous and non ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum.  Paper – inorganic papers, cellulose papers, rag stock, rag stripping, coloring and beating operations, copying paper, printing paper and electric insulating papers, paper adhesives.  Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, styrene beads, substrate for graft polymerization, template in acrylic polymerization.  Water and Waste Treatment, and Hygiene – clogging of reverse osmosis membranes, water treatment in fish hatchery ponds, removal of oil, dyes from waste water and waste water clarifier in papermaking, in deodorants for neutralization of irritant and poisonous gas, in air conditioning filters. Polyvinylpyrrolidone (PVP K 85) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/85 to 85/70 vinyl acetate to vinylpyrrolidone. PVP K 85 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (85, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 85 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP K 85 Copolymer? PVP K 85 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP K 85 copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP K 85 copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 85 copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP K 85 E and I copolymer Series To fit many application areas, the E and I series of PVP K 85 copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. The PVP K 85 copolymer PVP K 85 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP K 85 W copolymers PVP K 85 copolymer is a 70/85 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 85 W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 85 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 85 E-735 copolymer, PVP K 85 E-535 copolymer and PVP K 85 E- 335 copolymer. In general, PVP K 85 copolymer is less hygroscopic than PVP. PVP K 85 copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 85 copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 85 copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 85 copolymer is used as a binder to allow the aqueous processing of photoresists. Storage and handling PVP K 85 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 85 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 85 ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/85 to 85/70 vinyl acetate to vinylpyrrolidone. PVP K 85 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (85, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 85 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 85 E- and I-series To fit more application areas, the E- and I-series of PVP K 85 copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP K 85 W copolymers PVP K 85 is a 70/85 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 85 W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 85 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 85, PVP K 85 E-535 and PVP K 85 E-335. In general, PVP K 85 is less hygroscopic than PVP. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 85 ) copolymer compositions (70/85, 60/40, 50/50 and 85/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 85 , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 85 acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 85 finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 85 thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 85 used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 85 provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 85 is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP K 85 is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 85 monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 85 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 85 (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 85 tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 85 Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP K 85 E and I copolymer Series To fit many application areas, the E and I series of PVP K 85 copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP K 85 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 85 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 85 ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/85 to 85/70 vinyl acetate to vinylpyrrolidone. PVP K 85 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (85, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 85 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 85 W copolymers PVP K 85 is a 70/85 copolymer of PVP K 85 and vinyl acetate supplied as a 50% solution in water. PVP K 85 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 85 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. USES Medical PVP K 85 was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 85 is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 85 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 85 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP K 85 is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP K 85 is used in as an adhesive in glue stick and hot-melt adhesives PVP K 85 is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 85 is used in as an emulsifier and disintegrant for solution polymerization PVP K 85 is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP K 85 is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 85 is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 85 is used in as a thickening agent in tooth whitening gels[10] PVP K 85 is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 85 is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP K 85 is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP K 85 is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP K 85 is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP K 85 binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 85 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP K 85 is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 85 is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 85 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 85 is useful for making an aqueous mounting medium.[16] PVP K 85 can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP K 85 The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 85 has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 85 component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 85 instead. Properties of PVP K 85 PVP K 85 is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 85 and its oxidized hydrolyzate. History of PVP K 85 PVP K 85 was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 85 was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production.

PVP K 90 PVP K 90 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP K 90 Copolymer? PVP K 90 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Storage and handling of PVP K 90 PVP K 90 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. The PVP K 90 E- and I-series To fit more application areas, the E- and I-series of PVP K 90 copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP K 90 W copolymers PVP K 90 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90, PVP K 90 E-535 and PVP K 90 E-335. In general, PVP K 90 is less hygroscopic than PVP. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. PVP K-90 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-90 solution is a film former. It is suggested for use in hair styling formualations. PVP K-90 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. Key Attributes of PVP K 90 Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring. High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts. Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone. Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications. Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application. Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes of PVP K 90 Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks. Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier. Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes. Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates. Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes. Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths. Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives. Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. Abstract of PVP K-90 solution In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 90) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 90 , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. The advantages of using PVP K 90 copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 90 copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP K 90 E and I copolymer Series To fit many application areas, the E and I series of PVP K 90 copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. PVP K 90 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 90 is a 70/30 copolymer of PVP K 90 and vinyl acetate supplied as a 50% solution in water. PVP K 90 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 90 acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 90 finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 90 thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 90 used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 90 provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 90 is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene. PVP K 90 is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 90 monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 90 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 90 (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 90 tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 90 Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. Uses of PVP K-90 solution Medical uses of PVP K-90 solution PVP K 90 was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 90 is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 90 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 90 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. PVP K 90 is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Properties of PVP K 90 PVP K 90 is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin). When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 90 and its oxidized hydrolyzate. History of PVP K 90 PVP K 90 was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 90 was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 90 copolymer PVP K 90 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. PVP K 90 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 90 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 E-735 copolymer, PVP K 90 E-535 copolymer and PVP K 90 E- 335 copolymer. In general, PVP K 90 copolymer is less hygroscopic than PVP. PVP K 90 copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 90 copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 90 copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 90 copolymer is used as a binder to allow the aqueous processing of photoresists. USES PVP K 90 is used in as an adhesive in glue stick and hot-melt adhesives PVP K 90 is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 90 is used in as an emulsifier and disintegrant for solution polymerization PVP K 90 is used in increase resolution in photoresists for cathode ray tubes (CRT) PVP K 90 is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 90 is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 90 is used in as a thickening agent in tooth whitening gels PVP K 90 is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 90 is used in as an additive to Doro's RNA extraction buffer PVP K 90 is used in as a liquid-phase dispersion enhancing agent in DOSY NMR PVP K 90 is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly PVP K 90 is used in as a stabilizing agent in all inorganic solar cells Other uses of PVP K-90 solution PVP K 90 binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 90 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP K 90 is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 90 is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 90 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 90 is useful for making an aqueous mounting medium. PVP K 90 can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production. Safety of PVP K 90 The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses, and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 90 has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 90 component of the solution. A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP. In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP. Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 90 instead.

PVP K 90 растворим в воде и многих органических растворителях, образует твердую, прозрачную, блестящую пленку.
PVP K 90 совместим с большинством неорганических солей и многими смолами.
ПВП К 90 стабилизирует эмульсии, дисперсии и суспензии.

КАС: 9003-39-8
ПФ: канал 4
МВт: 16.04246
ИНЭКС: 1312995-182-4

PVP K 90, также обычно называемый поливидоном или повидоном, представляет собой водорастворимый полимер, изготовленный из мономера N-винилпирролидона.
PVP K 90 доступен в диапазоне молекулярной массы и соответствующей вязкости и может быть выбран в соответствии с желаемыми свойствами применения.
В то время как PVP K 90 используется в качестве пленкообразователя в средствах для укладки волос, PVP K 90 также может использоваться в качестве стабилизатора эмульсии в кремах и лосьонах и в качестве диспергатора красок для волос. Кроме того, фармацевтический PVP K 90 можно использовать в зубных пастах и ополаскивателях для рта.
PVP K 90 выглядит как белый порошок.

ПВП К 90, сокращенно ПВП, представляет собой полимер винилпирролидона.
В зависимости от степени полимеризации ПВП К 90 подразделяется на растворимый ПВП и нерастворимый ПВПП (поливинилполипирролидон).
Молекулярная масса растворимого ПВП К 90 составляет от 8000 до 10000.
Растворимый ПВП К 90 можно использовать в качестве осаждающего агента, который может осаждаться за счет его взаимодействия с полифенолами.
Используя этот метод, ПВП К 90 легко может иметь остаточный ПВП в спирте.
В связи с накопительным эффектом ПВП К 90 внутри организма человека Всемирная организация здравоохранения не рекомендует применять это вещество.

В последние годы применение растворимого ПВП К 90 стало редкостью.
Нерастворимая система ПВП К 90 начала использоваться в пивоваренной промышленности с начала 1960-х годов.
PVP K 90 имеет относительную молекулярную массу, превышающую относительную массу более 700000.
ПВП К 90 представляет собой нерастворимый полимер, полученный в результате дальнейшего сшивания и полимеризации ПВП, и может быть использован в качестве адсорбента полифенолов с хорошей эффективностью.

ПВП К 90 является одним из трех основных фармацевтических новых наполнителей и может использоваться в качестве сорастворителя таблеток, гранул и инъекций, в качестве скользящего вещества капсул, в качестве диспергатора жидких препаратов и красителя, в качестве стабилизатора. чувствительных к ферментам и теплу лекарств, в качестве соосаждающего агента плохо растворимых лекарств и в качестве детоксиканта офтальмологических лекарств и лубрикантов.
ПВП К 90 используется в промышленности в качестве добавки к пенополистиролу, гелеобразующего агента для суспензионной полимеризации, стабилизатора и агента для обработки волокон, вспомогательных средств для обработки бумаги, клеев и загустителей.

PVP K 90 и его сополимеры CAP являются важным сырьем для косметики, в основном используемым для удерживания волос.
Пленка ПВП К 90, образующаяся на волосах, эластичная и блестящая, обладает отличной прочесываемостью и не содержит пыли.
Принятие различных категорий смолы может соответствовать различным климатическим условиям относительной влажности.
Таким образом, ПВП К 90 является незаменимым сырьем для кремов, гелей и муссов для укладки волос.
PVP K 90 также можно использовать для косметических средств, увлажняющих кожу и диспергаторов для окрашивания волос на основе жира, а также в качестве стабилизаторов пены и может улучшить консистенцию шампуня.
Нерастворимый ПВП К 90 является стабилизатором пива и сока, который может улучшить их прозрачность, цвет и вкус.

PVP K 90 – водорастворимый полиамид.
Коммерчески доступный ПВП К 90 подразделяется на четыре класса вязкости в соответствии с его значением пресс-К (значение Фикенчера): К-15, К-30, К-60, К-90, со средней молекулярной массой 10000, 40000, 160000. и 360000 соответственно.
Значение K или молекулярная масса являются важным фактором, определяющим различные свойства ПВП.
ПВП К 90 растворяется в воде, хлорсодержащих растворителях, спирте, амине, нитропарафине и низкомолекулярных жирных кислотах, взаиморастворим с большинством неорганических солей и различными смолами; нерастворим в ацетоне и эфире.

ПВП К 90, используемый для матрицы таблеток-капельниц, представляет собой воскообразное твердое вещество без запаха и вкуса от белого до бледно-желтого цвета с относительной плотностью 1,062 и рН 5% водного раствора от 3 до 7.
ПВП К 90 гигроскопичен и обладает хорошей термической стабильностью, может растворяться в различных органических растворителях и имеет высокую температуру плавления.
Добавление некоторых природных или синтетических полимеров или органических соединений может эффективно регулировать гигроскопичность и мягкость PVP K 90.
ПВП К 90 не вступает в химическую реакцию.
При нормальных условиях хранения сухой ПВП К 90 достаточно стабилен.
PVP K 90 обладает отличной физической инерцией и биосовместимостью, не раздражает кожу, не раздражает глаза, не вызывает аллергических реакций и не токсичен.

Из-за эффекта водородных связей или комплексообразования вязкость ПВП К 90 увеличивается, что дополнительно препятствует образованию и росту кристаллизованных зародышей лекарств, делая лекарство в аморфном состоянии.
Капельница, матрицей которой является ПВП К 90, может улучшить растворение и биодоступность плохо растворимых лекарств.
В целом, чем больше количество ПВП К 90, тем выше растворение и растворимость лекарственного средства в среде.
Susana et al. изучали растворение твердого диспергатора PVP K 90 слаборастворимого лекарственного средства альбендазола.
Повышенное количество ПВП К 90 может повысить скорость растворения и эффе��тивность лекарственного средства внутри твердого диспергатора.

Teresa и соавт. исследовали растворение плохо растворимых лекарственных средств, флунаризина, в твердом диспергаторе PVP K 90 и получили аналогичный вывод.
PVP K 90 также обнаружил, что чем выше его содержание, тем значительнее увеличение растворения.
ИР показал, что флунаризин и ПВП К 90 не вступают в химическую реакцию, за исключением некоторых случаев, когда наилучшая эффективность растворения достигается только при определенном соотношении некоторых препаратов с ПВП.
Tantishaiyakul et al. обнаружили, что: когда соотношение пироксикама: ПВП К 90 составляет 1:5 и 1:6, растворение твердого диспергатора является максимальным, в 40 раз превышающим растворение одного лекарственного средства в течение 5 минут.
PVP K 90 также может быть растворен в другой расплавленной матрице пилюли, такой как полиэтиленгликоль (ПЭГ), полиоксиэтиленмоностеарат (S-40), полоксамер и стеариловая кислота, глицерилмоностеарат и т. д. для получения сложной матрицы.

ПВП К 90, полимер винилпирролидинона, является вспомогательным веществом, используемым в качестве суспендирующего и диспергирующего агента.
Инъекционные препараты, содержащие полимеры с молекулярной массой порядка 12 000, вызывают болезненные локальные гранулематозные поражения.
Это привело к изъятию PVP K 90 из таких препаратов в некоторых странах.
PVP K 90 ранее также использовался в качестве расширителя плазмы, но, поскольку он изолировался в печени и селезенке, его использование было прекращено.
Однако ПВП К 90 по-прежнему широко используется в качестве носителя для офтальмологических препаратов и в качестве основного компонента искусственных слез.

Химические свойства ПВП К 90
Температура плавления: >300°С
Температура кипения: 90-93°С
Плотность: 1,69 г/см3
Температура хранения: 2-8°C
Растворимость H2O: растворим 100 мг/мл
Форма: порошок
Цвет: от белого до желто-белого
РН: 3,0-5,0
Растворимость в воде: Растворим в воде.
Чувствительный: гигроскопичный
Мерк: 14 7697
Стабильность: Стабильная. Несовместим с сильными окислителями.
Чувствителен к свету. гигроскопичен.
ИнХИ: ИнХИ=1S/C8H15NO/c1-3-7(2)9-6-4-5-8(9)10/h7H,3-6H2,1-2H3
InChIKey: FAAHNQAYWKTLFD-UHFFFAOYSA-N
IARC: 3 (Том 19, Доп. 7, 71) 1987 г.
Система регистрации веществ EPA: PVP K 90 (9003-39-8)

Обычно используемый уровень PVP K 90 в косметической промышленности - это K-30.
Промышленный ПВП К 90 представляет собой белый сыпучий порошок или твердые вещества с содержанием его в массовой доле 20%, 30%, 45% и 50% водного раствора.
ПВП К 90 растворим в воде и гигроскопичен, равновесная влажность составляет 1/3 от относительной влажности окружающей среды.
Подобно действию гидратации белка, каждый мономер связывается с 0,5 моль воды.
PVP K 90 не легко вступает в химическую реакцию.

При хранении в нормальных условиях сухой ПВП К 90 достаточно стабилен.
Раствор, прошедший обработку от плесени, также стабилен.
При нагревании на воздухе до 150 °C или при смешивании с персульфатом аммония для нагревания до 90 °C в течение 30 минут PVP K 90 превращается в нерастворимое в воде соединение.
В присутствии азосоединения или дихроматного окислителя свет превращает раствор ПВП К 90 в гель.
Совместное нагревание раствора PVP K 90 с сильным основанием (таким как силикат натрия или тринатрийфосфат) приводит к образованию осадка.
Многие различные соединения могут образовывать комплексы с ПВП.

Например, комплексы ПВП и йода очень стабильны, обладают хорошим бактерицидным действием и позволяют снизить его токсичность; Добавление сополимеров полиакриловой кислоты, дубильной кислоты или метилвинилового эфира и малеиновой кислоты к водному раствору ПВП К 90 приводит к образованию нерастворимых комплексов, нерастворимых в воде, спиртах и кетонах.
Но при обработке основанием для нейтрализации поликислота может обратить реакцию вспять; комплексообразование между ПВП К 90 и токсинами, лекарствами и ядохимикатами может снизить их токсичность; некоторые виды красителей также могут образовывать прочный комплекс с ПВП К 90, что является основанием для использования ПВП К 90 в качестве отбеливателя красителей.

ПВП К 90 представляет собой сшитый гомополимер чистого винилпирролидона.
PVP K 90 представляет собой гигроскопичный сыпучий порошок белого или почти белого цвета.
ПВП К 90 имеет легкий неприятный запах.
PVP K 90 нерастворим в обычных растворителях, таких как вода, этанол и эфир.
Таким образом, диапазон молекулярной массы PVP K 90 не может быть измерен.
Однако ПВП К 90 способен образовывать комплексы с различными видами веществ (такими как вещества класса «Ху», которые могут привести к обесцвечиванию различных вин и напитков).

Также ПВП К 90 легко удаляется после фильтрации из-за его нерастворимости.
PVP K 90 представляет собой мелкодисперсный гигроскопичный порошок от белого до кремово-белого цвета без запаха или почти без запаха.
ПВП К 90 со значениями К, равными или ниже 30, производятся методом распылительной сушки и имеют форму сфер.
Повидоны PVP K 90 и выше производятся барабанной сушкой в виде пластин.

ПВП К 90 растворим в воде и других полярных растворителях.
Например, ПВП К 90 растворим в различных спиртах, таких как метанол и этанол, а также в более экзотических растворителях, таких как глубокий эвтектический растворитель, образованный хлоридом холина и мочевиной (Релин).
В сухом виде ПВП К 90 представляет собой легкий чешуйчатый гигроскопичный порошок, легко поглощающий до 40% своего веса в атмосферной воде.
В растворе ПВП К 90 обладает отличными смачивающими свойствами и легко образует пленки.
Это делает ПВП К 90 хорошим в качестве покрытия или добавки к покрытиям.
Исследование 2014 года обнаружило флуоресцентные свойства PVP K 90 и его окисленного гидролизата.

Использование
В начале 1950-х годов старые лаки для волос с шеллаком и маслом были быстро заменены спреями PVP K 90, которые широко используются до сих пор.
PVP K 90 может образовывать на волосах влажную прозрачную пленку, которая блестит и обладает хорошим смазывающим эффектом.
PVP K 90 имеет хорошую совместимость с различными хорошими пропеллентами, а также обладает коррозионной стойкостью.
PVP K 90 широко используется в укладке волос, в качестве пленкообразователя в продуктах для расчесывания, в качестве креатинина и стабилизатора лосьонов и кремов по уходу за кожей, в качестве базового материала для косметики для глаз и лица и основы губной помады, а также в качестве диспергаторов красок для волос. и стабилизатор пены шампуня.

PVP K 90 оказывает дезинтоксикационное действие и может уменьшить раздражающее действие других препаратов на кожу и глаза.
PVP K 90 также используется в качестве моющих средств для зубных паст, желирующих агентов и антидотов.
Основным недостатком ПВП К 90 является его чувствительность к влаге.
Однако эту проблему можно решить, используя сополимер винилацетата, чтобы смягчить воздействие влаги и влажности.
Кроме того, PVP K 90 также широко применяется в фармацевтической, пищевой и текстильной промышленности.

Осветляющий агент; стабилизатор пигмента; коллоидный стабилизатор; PVP K 90 в основном используется для осветления пива и стабилизации качества (контрольное количество 8~20 г/100 л, выдерживается в течение 24 часов и удаляется фильтрацией), а также может применяться в сочетании с ферментами (протеазами) и белковыми адсорбентами.
PVP K 90 также используется для осветления вина и в качестве стабилизатора для предотвращения обесцвечивания (эталонное количество 24~72 г/100 л).
Осветляющие агенты; стабилизаторы; агент загустителя; наполнители для таблеток; диспергаторы; ПВП К 90 с молекулярной массой 360 000 часто используют в качестве осветлителя пива, уксуса и виноградного вина.
Используется в качестве фиксирующей жидкости для газовой хроматографии.

ПВП К 90 используется в качестве коллоидного стабилизатора и осветлителя для осветления пива. Применить надлежащее количество в соответствии с требованиями производства.
PVP K 90 может использоваться в фармацевтике, аквакультуре и животноводстве как дезинфицирующее средство для стерилизации кожи и слизистых.
Молекула ПВП К 90 имеет амидную связь для поглощения гидроксильных групп, расположенных в молекуле полифенола, с образованием водородных связей, и, следовательно, может использоваться в качестве стабилизатора пива, фруктового вина/виноградного вина и питьевого вина для продления срока их хранения и улучшения качества. прозрачность, цвет и вкус.
Продукты имеют две спецификации: одноразовый тип и тип регенерации.
Одноразовые изделия подходят для применения малыми и средними предприятиями; возобновляемые продукты требуют покупки специального фильтрующего оборудования; но поскольку PVP K 90 пригоден для повторного использования, он подходит для крупных пивоваренных заводов для повторного использования.

В ежедневной косметике ПВП К 90 и его сополимер обладают хорошими дисперсионными и пленкообразующими свойствами, поэтому их можно использовать в качестве фиксирующего л��сьона, спрея для волос и мусса для укладки, в качестве замутнителей для средств по уходу за волосами, в качестве стабилизатора пены шампуня. в качестве агента для укладки волн, а также в качестве диспергаторов и агентов сродства в краске для волос.
Добавление PVP K 90 в крем, солнцезащитный крем и средство для удаления волос может усилить смачивающий и смазывающий эффект.
Использование превосходных свойств ПВП К 90, таких как поверхностная активность, пленкообразующее и не раздражающее кожу, отсутствие аллергических реакций и т. д., открывает широкие перспективы его применения в средствах по уходу за волосами и кожей.

ПВП К 90 используется в качестве клея в клеевых стержнях; эмульгатор и разрыхлитель для растворной полимеризации; добавка к буферу для экстракции РНК Доро; в качестве агента, улучшающего жидкофазную дисперсию, в спектроскопии упорядоченной диффузии (DOSY) ЯМР и в качестве загустителя в гелях для отбеливания зубов.
PVP K 90 находит применение в продуктах личной гигиены, таких как шампуни и зубные пасты, в чернилах для струйных принтеров, а также в растворах для контактных линз.
ПВП К 90 используется в качестве пищевой добавки и в винодельческой промышленности как осветлитель для белого вина.
PVP K 90 используется в качестве укупорочного агента для синтеза серебряных нанопроводов с помощью полиольного процесса.

Фармацевтические приложения
Хотя ПВП К 90 используется в различных фармацевтических препаратах, в основном он используется в твердых лекарственных формах.
При таблетировании растворы ПВП К 90 используются в качестве связующих в процессах влажной грануляции.
ПВП К 90 также добавляют к порошковым смесям в сухом виде и гранулируют на месте путем добавления воды, спирта или водно-спиртовых растворов.
PVP K 90 используется в качестве солюбилизатора в пероральных и парентеральных препаратах, и было показано, что он улучшает растворение плохо растворимых лекарств из твердых лекарственных форм.

Растворы PVP K 90 также можно использовать в качестве покрывающих агентов или связующих при нанесении активных фармацевтических ингредиентов на подложку, такую как сахарные шарики.
PVP K 90 дополнительно используется в качестве суспендирующего, стабилизирующего или повышающего вязкость агента в ряде суспензий и растворов для местного и перорального применения.
Растворимость ряда плохо растворимых активных лекарственных средств может быть увеличена путем смешивания с повидоном.
Специальные марки апирогенного ПВП К 90 доступны и используются в парентеральных препаратах.

Медицинский
ПВП К 90 используется в качестве связующего во многих фармацевтических таблетках; он просто проходит через тело при пероральном приеме.
ПВП К 90 при добавлении к йоду образует комплекс, называемый повидон-йод, который обладает дезинфицирующими свойствами.
PVP K 90 используется в различных продуктах, таких как растворы, мази, пессарии, жидкое мыло и хирургические скрабы.
PVP K 90 продается, среди прочего, под торговыми названиями Pyodine и Betadine.
PVP K 90 используется при плевродезе (сращении плевры из-за непрекращающегося плеврального выпота).
Для этой цели PVP K 90 столь же эффективен и безопасен, как и тальк, и может быть предпочтительным из-за доступности и низкой стоимости.

PVP K 90 используется в некоторых контактных линзах и их упаковочных растворах.
PVP K 90 снижает трение, действуя таким образом как смазка или смачивающий агент, встроенный в линзу.
PVP K 90 используется в качестве смазывающего вещества в некоторых глазных каплях, напр. Bausch & Lomb's Soothe.
PVP K 90 использовался в качестве расширителя объема плазмы для пострадавших после 1950-х годов.

PVP K 90 не рекомендуется использовать в качестве расширителя объема из-за его способности вызывать высвобождение гистамина, а также влиять на формирование группы крови.
Вскрытие показало, что PVP K 90 способствует повреждению легочных сосудов у лиц, злоупотребляющих психоактивными веществами, которые вводили инъекционные фармацевтические таблетки, предназначенные для перорального употребления.
Долгосрочные эффекты кросповидона или повидона в легких неизвестны.

Технические
PVP K 90 также используется во многих технических приложениях:
в качестве специальной добавки для аккумуляторов, керамики, стекловолокна, чернил и бумаги для струйных принтеров, а также в процессе химико-механической планаризации,
как эмульгатор и разрыхлитель для растворной полимеризации,
увеличить разрешение в фоторезистах для электронно-лучевых трубок (ЭЛТ),
при водной закалке металла,
для производства мембран, таких как фильтры для диализа и очистки воды,
в качестве связующего и комплексообразователя в сельскохозяйственных применениях, таких как защита растений, обработка семян и покрытие,
в качестве загустителя в гелях для отбеливания зубов,
как вспомогательное средство для повышения растворимости лекарственных средств в жидких и полужидких лекарственных формах (сиропы, мягкие желатиновые капсулы) и как ингибитор перекристаллизации,
в качестве добавки к буферу для экстракции РНК Доро,
в качестве агента, улучшающего жидкофазную дисперсию, в DOSY ЯМР,
в качестве поверхностно-активного вещества, восстановителя, агента, контролирующего форму, и диспергатора в наночастицах, синтезе и их самосборке,
в качестве стабилизатора во всех неорганических солнечных элементах.

Другое использование
PVP K 90 благодаря своей полярности исключительно хорошо связывается с полярными молекулами.
Это привело к применению PVP K 90 в покрытиях для бумаги и прозрачных пленок для струйных принтеров фотографического качества, а также в чернилах для струйных принтеров.
PVP K 90 также используется в продуктах личной гигиены, таких как шампуни и зубные пасты, в красках и клеях, которые необходимо увлажнять, таких как почтовые марки и конверты старого образца.
PVP K 90 также использовался в растворах для контактных линз и в растворах для закалки стали.
PVP K 90 является основой первых формул лаков и гелей для волос, и до сих пор продолжает оставаться компонентом некоторых из них.
В качестве пищевой добавки PVP K 90 является стабилизатором и имеет номер E E1201.
PVPP (кросповидон) – Е1202.

PVP K 90 также используется в винодельческой промышленности в качестве осветляющего агента для белого вина и некоторых сортов пива.
В лабораториях экстракорпорального оплодотворения PVP K 90 используется для замедления образования сперматозоидов с целью их захвата, например, для ИКСИ.
В молекулярной биологии ПВП К 90 можно использовать в качестве блокирующего агента при Саузерн-блоттинге в составе буфера Денхардта.
PVP K 90 также исключительно хорошо поглощает полифенолы во время очистки ДНК.
Полифенолы распространены во многих растительных тканях и могут деактивировать белки, если их не удалить, и поэтому ингибируют многие последующие реакции, такие как ПЦР.
В микроскопии ПВП используется для изготовления водной заливочной среды.
PVP K 90 можно использовать для скрининга фенольных свойств, как указано в исследовании 2000 года о влиянии растительных экстрактов на выработку инсулина.

Идентификационный тест
Растворимость: растворим в воде, этаноле и хлороформе и нерастворим в эфире.
Это измеряется методом OT-42.
Испытание на осаждение бихромата: в 5 мл 2% раствора пробы добавить 5 мл разбавленного раствора соляной кислоты (TS-117), затем добавить 5 мл воды, 2 мл 10% раствора бихромата калия и 2 мл.
При этом должен образоваться оранжевый осадок.
Взять 75 мг азотнокислого кобальта и 300 мг тиоцианата аммония для растворения в 2 мл воды; добавить 5 мл 2% водного раствора образца; после перемешивания добавить разбавленный испытательный раствор соляной кислоты (TS-117) для подкисления.
При этом должен образоваться светло-голубой осадок.
Возьмите 5 мл 2% раствора пробы; добавить 1 мл 25 % соляной кислоты, 5 мл 5 % хлорида бария и 1 мл 5 % молибденово-вольфрамового раствора фосфорной кислоты.

При этом должно образоваться много белого осадка, который постепенно синеет на солнце.
Значение pH 5% раствора пробы должно составлять от 3,0 до 3,7.
Это измеряется обычными средствами.
Добавление нескольких капель тестового раствора йода (TS-124) к 5 мл 0,5% раствора образца должно дать темно-красный цвет.
Отбирают 1 г пробы, добавляют к 10 мл воды в виде суспензии, добавляют 0,1 мл испытуемого раствора йода (TS-124), после перемешивания встряхиванием в течение 30 с, иодообразующий раствор должен обесцвечиваться (отличить поливинилпирролидон, поскольку поливинилпирролидон может образовывать красный цвет).
Добавьте 1 мл исследуемого раствора крахмала (TS-235), после встряхивания и перемешивания не должно образовываться голубого окрашивания. для получения синего цвета.

Способ производства
Неочищенный продукт PVP K 90 получается в результате полимеризации винилпирролидона в присутствии основного катализатора или в присутствии N,N'-дивиниламидина и последующей реакции сшивания.
Затем используйте воду, 5% уксусную кислоту и 50% этанол ��ля кипячения с обратным холодильником до тех пор, пока экстракт не станет ≤50 мг/кг (в течение более 3 часов).
30-60%-ный водный раствор очищенного 1-винил-2-пирролидона в присутствии аммиака или аминов, а также с перекисью водорода в качестве катализатора вступает в реакцию сшивания и гомополимеризации при температуре 50°С. C и подвергают дальнейшей очистке с получением конечного продукта.

PVP K 90 производится по процессу Реппе.
Ацетилен и формальдегид реагируют в присутствии высокоактивного катализатора ацетилида меди с образованием бутиндиола, который гидрируется до бутандиола, а затем подвергается циклодегидрированию с образованием бутиролактона.
ПВП К 90 получают реакцией бутиролактона с аммиаком.
Затем следует реакция винилирования, в которой пирролидон и ацетилен реагируют под давлением.
Мономер, винилпирролидон, затем полимеризуется в присутствии комбинации катализаторов для получения повидона.

Контактные аллергены
PVP K 90 широко используется в косметических средствах, таких как средства по уходу за волосами, и в медицинских изделиях.
ПВП К 90 действует как йодофор в йод-поливинилпирролидоне.
PVP K 90 является раздражителем и считается аллергеном в некоторых случаях дерматита, вызванного йод-поливинилпирролидоном (хотя йод, скорее всего, является гаптеном).
PVP K 90 может вызывать контактную крапивницу I типа или анафилаксию.

Биохимия/физиол Действия
PVP K 90 может связываться с полифенолом.
Так, известно, что ПВП К-90 используется для выделения РНК из растений, богатых полифенолами.
ПВП К 90 широко используется в синтезе наночастиц.

Синонимы
N-ВИНИЛ-2-ПИРРОЛИДОН
88-12-0
1-винилпирролидин-2-он
N-винилпирролидон
1-винил-2-пирролидон
9003-39-8
N-винил-2-пирролидинон
1-винил-2-пирролидинон
Винилпирролидон
Повидон
1-этенилпирролидин-2-он
N-винилпирролидинон
2-пирролидинон, 1-этенил-
1-винилпирролидон
Винилбутиролактам
Винилпирролидинон
V-пирол
Лувискол
Пласдон
1-винилпирролидинон
25249-54-1
Винил-2-пирролидон
N-винилпирролидон
1-Этенил-2-пирролидинон
N-винилпирролидон-2
2-пирролидинон, 1-винил-
1-винил-2-пирролидинон, мономер
ПВП
СНБ 10222
МПК 90
ПВП 40
DTXSID2021440
143 РП
В 717
1-винилпирролидин-2-он
К 15
К 90
ПВП-40
ЧЕБИ:82551
MFCD00003197
НБК-10222
76Х9Г81541
DTXCID101440
WLN: /T5NVTJ AY*1*/
MFCD01076626
КАС-88-12-0
К 25
К 115
ХДБ 7231
ИНЭКС 201-800-4
БРН 0110513
КРИС 8581
ПовидонПВП
винилпирролидон
УНИИ-76H9G81541
N-винилпирролидон
N-винилпирролидинон
1-винил-2-пирролидон
ПОВИДОН МОНОМЕР
ВИНИЛБУТИЛОЛАКТАМ
N-винилпирролидин-2-он
N-винилпирролидин-2-он
N-винилпирролидин-2-он
ПВП К3О
Кросповидон ~ 40 000
ЕС 201-800-4
SCHEMBL10869
WLN: T5NVTJ A1U1
ПВП К15
ПВП К30
ПВП-К30
ПОВИДОН МОНОМЕР [MI]
ВИНИЛПИРРОЛИДОН (ВП)
КЕМБЛ1878943
ПВП - К-30 (фармацевтический класс)
N-ВИНИЛПИРРОЛИДОН [INCI]
1-винил-2-пирролидон (стабилизированный гидроксидом аммония 200 ppm)
NSC10222
Токс21_202462
Токс21_300073
NSC114022
НСК142693
НСК683040
N-винил-2-пирролидон, оптическая чистота
Поливинилпирролидон (молекулярная масса ~40 000)
АКОС000119985
N-ВИНИЛ-2-ПИРРОЛИДОН [IARC]
AT18510
CS-W020981
ФГ-0420
НСК-114022
НСК-142693
НСК-683040
NCGC00166252-01
NCGC00166252-02
NCGC00166252-03
NCGC00254200-01
NCGC00260011-01
2-ПИРРОЛИДИНОН, 1-ЭТЕНИЛ-[HSDB]
FT-0608329
FT-0645144
FT-0655284
V0026
EN300-19745
C19548
А817742
А843417
Q420628
СР-01000944531
J-015891
СР-01000944531-1
W-100417
1-винил-2-пирролидинон, SAJ первого сорта, >=99,0%
F8881-5579
Z104475034
3-ХЛОР-5,6-ДИФТОР-1-БЕНЗОТИОФЕН-2-КАРБОНИЛХЛОРИД
1-винил-2-пирролидинон, содержит гидроксид натрия в качестве ингибитора, >=99%
1-винил-2-пирролидинон, вторичный фармацевтический стандарт; Сертифицированный справочный материал
1-винил-2-пирролидон (стабилизированный N,N'-ди-втор-бутил-п-фенилендиамином)

SYNONYMS PVP, Polyvidone, Povidone;Polyvinylpyrrolidone Standard (Mw 3500 K12);Polyvinylpyrrolidone Standard (Mw 8.000 K16-18);Polyvinylpyrrolidone Standard (Mw 10.000 K13-18);Polyvinylpyrrolidone Standard (Mw 24.000 K23-27);Polyvinylpyrrolidone Standard (Mw 30.000);Polyvinylpyrrolidone Standard (Mw 40.000 K-30);Polyvinylpyrrolidone Standard (Mw 55.000);Polyvinylpyrrolidone Standard (Mw 58.000 K29-32) CAS NO:9003-39-8

PVP K 90 Solution PVP K-90 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-90 solution is a film former. It is suggested for use in hair styling formualations. PVP K-90 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. Key Attributes of PVP K 90 solution  Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring.  High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.  Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone.  Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications.  Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.  Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes of PVP K 90 solution  Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks.  Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier.  Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes.  Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates.  Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes.  Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths.  Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives.  Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. What is PVP K 90 solution Copolymer? PVP K 90 solution Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Storage and handling of PVP K 90 solution PVP K 90 solution copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 solution polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 solution copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 solution copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 90 solution E- and I-series To fit more application areas, the E- and I-series of PVP K 90 solution copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP K 90 solution W copolymers PVP K 90 solution is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 solution copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 solution, PVP K 90 solution E-535 and PVP K 90 solution E-335. In general, PVP K 90 solution is less hygroscopic than PVP. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP K 90 solution copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP K 90 solution copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 90 solution copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP K 90 solution E and I copolymer Series To fit many application areas, the E and I series of PVP K 90 solution copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Abstract of PVP K-90 solution In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 90 solution , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 90 solution acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 90 solution finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 90 solution thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 90 solution used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 90 solution provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 90 solution is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene. PVP K 90 solution is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 90 solution monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 90 solution Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 90 solution (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 90 solution tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 90 solution Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. PVP K 90 solution copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 solution polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 solution copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 solution copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 90 solution is a 70/30 copolymer of PVP K 90 solution and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 solution copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Uses of PVP K-90 solution Medical uses of PVP K-90 solution PVP K 90 solution was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 90 solution is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 90 solution added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 90 solution is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. PVP K 90 solution is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical uses of PVP K-90 solution PVP K 90 solution is used in as an adhesive in glue stick and hot-melt adhesives PVP K 90 solution is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 90 solution is used in as an emulsifier and disintegrant for solution polymerization PVP K 90 solution is used in increase resolution in photoresists for cathode ray tubes (CRT) PVP K 90 solution is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 90 solution is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 90 solution is used in as a thickening agent in tooth whitening gels PVP K 90 solution is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 90 solution is used in as an additive to Doro's RNA extraction buffer PVP K 90 solution is used in as a liquid-phase dispersion enhancing agent in DOSY NMR PVP K 90 solution is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly PVP K 90 solution is used in as a stabilizing agent in all inorganic solar cells Other uses of PVP K-90 solution PVP K 90 solution binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 90 solution is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP K 90 solution is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 90 solution is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 90 solution can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 90 solution is useful for making an aqueous mounting medium. PVP K 90 solution can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production. Safety of PVP K 90 solution The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses, and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 90 solution has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 90 solution component of the solution. A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP. In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP. Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 90 solution instead. Properties of PVP K 90 solution PVP K 90 solution is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin). When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 90 solution and its oxidized hydrolyzate. History of PVP K 90 solution PVP K 90 solution was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 90 solution was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 90 solution copolymer PVP K 90 solution copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. PVP K 90 solution copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 90 solution copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 solution E-735 copolymer, PVP K 90 solution E-535 copolymer and PVP K 90 solution E- 335 copolymer. In general, PVP K 90 solution copolymer is less hygroscopic than PVP. PVP K 90 solution copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 90 solution copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 90 solution copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 90 solution copolymer is used as a binder to allow the aqueous processing of photoresists.

PVP K 90 Solution 20% PVP K 90 Solution 20% is a film former in hair styling products. PVP is an emulsion stabilizer in creams and lotions. PVP can also be a dispersant for hair colorants. PVP K 90 is available as 100% powder and as 20% aqueous solution. PVP (Polyvinylpyrrolidone) K-90 polymer is a hygroscopic, amorphous polymer. PVP K 90 solution 20% is a linear nonionic polymer that is soluble in water and organic solvents and is pH stable. PVP K 90 solution 20% forms hard glossy transparent films and have adhesive and cohesive properties. Ashland Specialty Ingredients has the capability to dial the K-value to meet specific customer needs. PVP K-90 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-90 solution by Ashland Specialty Chemical is a film former. It is suggested for use in hair styling formualations. PVP K-90 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. Key Attributes of PVP K 90 solution 20%  Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring.  High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.  Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone.  Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications.  Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.  Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes of PVP K 90 solution 20%  Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks.  Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier.  Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes.  Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates.  Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes.  Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths.  Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives.  Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. What is PVP K 90 solution 20% Copolymer? PVP K 90 solution 20% Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Storage and handling PVP K 90 solution 20% copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 solution 20% polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution 20% ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 solution 20% copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 solution 20% copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 90 solution 20% E- and I-series To fit more application areas, the E- and I-series of PVP K 90 solution 20% copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP K 90 solution 20% W copolymers PVP K 90 solution 20% is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution 20% W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 solution 20% copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 solution 20%, PVP K 90 solution 20% E-535 and PVP K 90 solution 20% E-335. In general, PVP K 90 solution 20% is less hygroscopic than PVP. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP K 90 solution 20% copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP K 90 solution 20% copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 90 solution 20% copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP K 90 solution 20% E and I copolymer Series To fit many application areas, the E and I series of PVP K 90 solution 20% copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution 20% ) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 90 solution 20% , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 90 solution 20% acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 90 solution 20% finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 90 solution 20% thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 90 solution 20% used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 90 solution 20% provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 90 solution 20% is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP K 90 solution 20% is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 90 solution 20% monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 90 solution 20% Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 90 solution 20% (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 90 solution 20% tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 90 solution 20% Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP K 90 solution 20% E and I copolymer Series To fit many application areas, the E and I series of PVP K 90 solution 20% copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP K 90 solution 20% copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 solution 20% polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution 20% ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 solution 20% copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 solution 20% copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 90 solution 20% W copolymers PVP K 90 solution 20% is a 70/30 copolymer of PVP K 90 solution 20% and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution 20% is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 solution 20% copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Uses Medical PVP K 90 solution 20% was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 90 solution 20% is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 90 solution 20% added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 90 solution 20% is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP K 90 solution 20% is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP K 90 solution 20% is used in as an adhesive in glue stick and hot-melt adhesives PVP K 90 solution 20% is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 90 solution 20% is used in as an emulsifier and disintegrant for solution polymerization PVP K 90 solution 20% is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP K 90 solution 20% is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 90 solution 20% is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 90 solution 20% is used in as a thickening agent in tooth whitening gels[10] PVP K 90 solution 20% is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 90 solution 20% is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP K 90 solution 20% is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP K 90 solution 20% is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP K 90 solution 20% is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP K 90 solution 20% binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 90 solution 20% is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP K 90 solution 20% is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 90 solution 20% is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 90 solution 20% can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 90 solution 20% is useful for making an aqueous mounting medium.[16] PVP K 90 solution 20% can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP K 90 solution 20% The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 90 solution 20% has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 90 solution 20% component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 90 solution 20% instead. Properties of PVP K 90 solution 20% PVP K 90 solution 20% is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 90 solution 20% and its oxidized hydrolyzate. History of PVP K 90 solution 20% PVP K 90 solution 20% was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 90 solution 20% was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 90 solution 20% copolymer PVP K 90 solution 20% copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP K 90 solution 20% W copolymers PVP K 90 solution 20% copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution 20% W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 90 solution 20% copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 solution 20% E-735 copolymer, PVP K 90 solution 20% E-535 copolymer and PVP K 90 solution 20% E- 335 copolymer. In general, PVP K 90 solution 20% copolymer is less hygroscopic than PVP. PVP K 90 solution 20% copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 90 solution 20% copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 90 solution 20% copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 90 solution 20% copolymer is used as a binder to allow the aqueous processing of photoresists.

Polyvinylpyrrolidone ;‘Plasdone’, PVP, Polyvidone, Povidone; POLYVINYLPYRROLIDONE K 30 cas no:9003-39-8

CAS NUMBER: 9003-39-8 Linear Formula (C6H9NO)n MDL number MFCD00149016 3D model (JSmol) Interactive image Abbreviations PVP, PVPP, NVP, PNVP ChEMBL ChEMBL1909074 ☒ ChemSpider none ECHA InfoCard 100.111.937 E number E1201 (additional chemicals) SMILES Properties Chemical formula (C6H9NO)n Molar mass 2,500 - 2,500,000 g·mol-1 Appearance white to light yellow, hygroscopic, amorphous powder Density 1.2 g/cm3 Melting point 150 to 180 °C (302 to 356 °F; 423 to 453 K) (glass temperature) Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Appearance (Colour) White to off - white Appearance (Form) Crystalline powder Solubility (Turbidity) 10% aq. solution Clear Nitrogen content (N) 11.5 - 12.5% pH (5% aq. solution) 3.0 - 7.0 Sulphated Ash max. 0.1% Heavy Metals (Pb) max. 0.001% K-value ~ 30 Vinyl pyrrolidone max. 0.8% Water (KF) max. 5% PVP K-30 is a hygroscopic, amorphous polyvinylpyrrolidone. Used in industrial, specialty and imaging coatings & paints and as a media component in digital ink jet-printing. Offers high polarity, dispersancy, hydrophilicity, adhesion, cohesivity and high glass transition temperature. PVP K-30 can be plasticized with water and most common organic plasticizers. They are linear nonionic polymers thar are soluble in water and organi solvents and are pH stable. PVP K-30 forms hard glossy transparent films and have adhesive, cohesive and dispersive properties. PVP K-30 100% Powder is soluble in water and many organic solvents and it forms hard, transparent, glossy film. PVP is compatible with most inorganic salts and many resins. PVP stabilizes emulsions, dispersions and suspensions. While PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-30 100% Powder appears as a white powder. Applications adhesives, ceramics, glass (fibers), coating/inks, electronic appliations, lithography and photography, fibers and textiles, membranes, metallurgy, paper, polymerizations, water and waste teratment, and hygiene. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone: PVP was used as a plasma volume expander for trauma victims after the 1950s. It is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Examples of this use include Bausch & Lomb's Ultra contact lenses with MoistureSeal Technology[6] and Air Optix contact lens packaging solution (as an ingredient called "copolymer 845").[7] PVP is used as a lubricant in some eye drops, Soothe.[8] Technical PVP is also used in many technical applications: as an adhesive in glue stick and hot-melt adhesivesas a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process as an emulsifier and disintegrant for solution polymerization to increase resolution in photoresists for cathode ray tubes (CRT)[9] in aqueous metal quenching for production of membranes, such as dialysis and water purification filters as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating as a thickening agent in tooth whitening gels[10] as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation as an additive to Doro's RNA extraction buffer[citation needed] as a liquid-phase dispersion enhancing agent in DOSY NMR [11] as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] as a stabilizing agent in all inorganic solar cells[13] Other uses PVP binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP is useful for making an aqueous mounting medium.[16] PVP can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP instead.[22][23] Properties PVP is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP and its oxidized hydrolyzate.[26] History PVP was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production Vinylpyrrolidone polymer Polyvinylpyrrolidone is abbreviated as PVP, and is the polymer of vinylpyrrolidone. According to the different degree of polymerization, it is further classified into soluble PVP and insoluble PVPP (polyvinyl polypyrrolidone). Molecular weight of the soluble PVP is 8,000 to 10,000.The soluble PVP can be used as a precipitating agent which can be settle down through its action with polyphenols. Using this method, it is easily to have residual PVP in the alcohol. Due to the savings effect of PVP inside the human body, the World Health Organization doesn't recommend to apply this substance. In recent years, the use of soluble PVP has been rare. Insoluble PVPP system had began to be used in the beer industry since the early 1960s. It has a relative molecule weight greater than the relative mass greater than 700,000. It is a insoluble polymer derived from the further cross-linking and polymerization of PVP and can be used as an adsorbent of polyphenols with a good efficacy. The molecular formula of Polyvinylpyrrolidone The molecular formula of Polyvinylpyrrolidone Polyvinylpyrrolidone PVP is one of the three major pharmaceutical new excipients and can be used as the co-solvent of tablets, granules, and injection, as the glidant of capsules, as the dispersant agent of liquid preparations and the colorant, as the stabilizer of enzyme and heat sensitive drug, as the co-precipitating agent of poorly soluble drugs, and as the detoxicant of ophthalmic drugs and lubricants. It is industrially used as expanded polystyrene additive, as the gelling agents for suspension polymerization, stabilizer, and fiber treating agents, paper processing aids, adhesives, and thickening agents. Polyvinylpyrrolidone PVP and its copolymers CAP is an important raw material of cosmetics, mainly used for hair retaining agent. The film it formed in the hair is elastic and shiny, and has excellent carding property as well as being free of dust. Adopting different category of resin can meet various kinds of relative humidity climatic conditions. Therefore, it is an indispensable raw material in styling hair cream, hair gel, and mousse. It can also be used for the cosmetics of skin moisturizing agents and the dispersants for grease based hair dying, also as foam stabilizers, and can improve the consistency of the shampoo. Insoluble PVP is the stabilizer of beer and juice which can improve its transparency, color, and flavor. Water-soluble polyamides Polyvinyl pyrrolidone (PVP) is a water soluble polyamide. Commercially available PVP is divided into four viscosity grades according to its press K value (Fikentscher K value): K-15, K-30, K-60, K-90, with the average molecular weight being 10,000, 40000,160000, and 360000, respectively. K value or molecular weight is an important factor which decides the various properties of PVP. Polyvinyl pyrrolidone (PVP) is dissolved in water, chlorinated solvents, alcohol, amine, nitro-paraffin and low molecular weight fatty acids, and is mutually soluble with most inorganic salts and a variety of resin; insoluble in acetone and ether. PVP used for the matrix of dropping pill matrix is odorless, tasteless, white to pale yellow waxy solid with the relative density being 1.062, and its 5% aqueous solution pH being 3 to 7. PVP is hygroscopic and of good thermal stability, and can be dissolved in various kinds of organic solvents, and has high melting point. Adding certain natural or synthetic polymers or organic compounds can effectively adjust the PVP's hygroscopicity and softness. PVP is not prone to have chemical reaction. Under normal storage conditions, dry PVP is quite stable. PVP has excellent physical inertia and biocompatibility and has not stimulation to skin, eyes no stimulation with no allergic reactions and being non-toxic. Because of the hydrogen bonding or complexation effect, PVP's viscosity is increased and this further inhibits the formation and growth of crystallized nuclei of drugs, making the drug being in the amorphous state. The dropping pill whose matrix is PVP can enhance the dissolution and bioavailability of poorly soluble drugs. In general, the greater the PVP amount, the higher dissolution and solubility of drug in the medium. Susana et al have studied the dissolution of the PVP solid dispersant of the slightly soluble drug albendazole. The increased amount of PVP (k30) can increase the dissolution rate and efficiency of drug inside the solid dispersant. Teresa et al have studied the dissolution of the poorly soluble drugs, flunarizine in PVP solid dispersant and obtained similar conclusion. PVP also found that the higher the content, the more significant increase in dissolution. IR has showed that flunarizine and PVP has no chemical reaction except in some cases that a best dissolution efficacy is obtained only in certain ratio between some drugs with the PVP. Tantishaiyakul et al has found that: when the ratio of piroxicam: PVP is 1:5 and 1:6, the dissolution of the solid dispersant is the largest with a 40 times as high as that of single drug within 5min. PVP can also be dissolved in another molten dropping pill matrix, such as polyethylene glycol (PEG), polyoxyethylene monostearate (S-40), poloxamer and stearyl acid, glyceryl monostearate, etc for making complex matrix. The above information is edited by the Chemicalbook of Dai Xiongfeng. Physical and chemical properties Commonly used PVP level in the cosmetic industry is K-30. Commercialized PVP is white and free flowing powder or solids with its content in the mass fraction of 20%, 30%, 45% and 50% aqueous solution. PVP is soluble in water and is hygroscopic with a moisture equilibrium being 1/3 of the relative humidity of the environment. Similar as the protein hydration action, each monomer associates with 0.5mol water.Chart 1 and Chart 2 lists the reference quality standard of various types of polyvinylpyrrolidone PVP: Food grade and pharmaceutical grade polyvinylpyrrolidone PVP Chart 1: Food grade and pharmaceutical grade polyvinylpyrrolidone PVP Cosmetics and industrial polyvinylpyrrolidone PVP (Luvikol K, BASF) Chart 2: Cosmetics and industrial polyvinylpyrrolidone PVP (Luvikol K, BASF) PVP is not easy to have chemical reaction. When stored at normal conditions, dry PVP is quite stable. Solution undergone mildew treatment is also stable. When heated in air to 150 °C or mixed with ammonium persulfate to heat at 90 °C for 30min, PVP will be exchanged to become a water-insoluble compound. In the presence of azo compound or a dichromate oxidizing agent, light will cause PVP solution to become gel. The co-heating of PVP solution with strong base (such as sodium silicate or trisodium phosphate) will generate precipitation. Many different compounds can generate complexes with PVP. For example, the complexes of PVP and iodine is very stable and have a good bactericidal effect and can reduce its toxicity; Adding the copolymers of the polyacrylic acid, tannic acid or methyl vinyl ether and maleic acid to the aqueous solution of PVP will generate insoluble complexes which are insoluble in water, alcohols and ketones. But when being treated with base for neutralize the poly-acid can reverse the reaction; complexation between PVP and toxins, drugs and toxic chemicals can reduce their toxicity; some kinds of dyes can also form a strong complex with PVP, which is the basis for using PVP as a dye bleaching agent. The use of polyvinylpyrrolidone In the early 1950s, older, with shellac and oil-based hairspray had been rapidly replaced by PVP sprays which are still widely used until now. It can form wet, transparent film on the hair which is shiny and has good lubrication effect. PVP has good compatibility with a variety of good propellant and also has corrosion resistance. It is widely used in hair styling, as the film former in combing products, as the creatinine and stabilizer of skin care lotions and creams, as the base stock material for eye and facial cosmetics and lipstick base, and also as hair dye dispersants and shampoo foam stabilizer. PVP has detoxification effect and can reduce the irritation effects of other preparation on the skin and eyes. It is also used as toothpaste detergents, gelling agents and antidotes. The main drawback of PVP is its sensitivity to moisture. However, this issue can be tackled by using its vinyl acetate copolymer in order to mitigate the effects of moisture and humidity. In addition, PVP also has wide application in the pharmaceutical, beverage and textile industries. Rheological properties of solutions Water and methanol is the preferred solvent of PVP. pH value has little effect on the viscosity of the aqueous solution of PVP, for example, at 25 °C, pH range: 0.1~10, aqueous solution of PVP K-30 with a mass fraction of 5% concentration has a viscosity of 2.3~2.4mPa • s; in concentrated hydrochloric acid, this is 4.96mPa • s. Effect of temperature on the viscosity of the PVP aqueous solution is also relatively not obvious. Un-cross-linked PVP solution is not particularly thixotropic unless under very high concentration and display a short relaxation time. The chart 3 below lists the viscosity of PVP K-30 in a variety of solvents. Viscosity of PVP K-30 in various organic solvents (w %) (At room temperature) Chart 3: Viscosity of PVP K-30 in various organic solvents (w %) (At room temperature) Reference: Edited by Binyi Qiu, "Compendium of cosmetic chemistry and technology" Volume 1 Beijing: China Light Industry Press, 1997. Compatibility Polyvinylpyrrolidone is mainly used as pharmaceutical excipient, blood compatibilizer, cosmetics thickening agents, latex stabilizers, and clarifying agent of beer brewing. Not matter whether in solution or in the form of film, PVP always has a high degree of compatibility. It has good compatibility with various kinds of inorganic salt solution, many natural and synthetic resins and other chemical compatibility. Examples of their compatibility are seen at chart 4 and Figure 5. The compatibility of PVP and some other substances in water and ethanol Chart 4: The compatibility of PVP and some other substances in water and ethanol The solubility and compatibility of PVP in various solvents Chart 5: The solubility and compatibility of PVP in various solvents Safety PVP is physiologically inert. Acute oral toxicity of PVP: LD50 > 100g/kg. It does not irritate the skin or eyes, do not cause skin allergies. A large number of long-term toxicology studies have confirmed that polyvinylpyrrolidone (PVP) can tolerate intraperitoneal, intramuscular, intravenous administration and parenteral applications. Subacute and chronic toxicity result was negative. Identification test Solubility: soluble in water, ethanol and chloroform and insoluble in ether. This is measured by the OT-42 method. Dichromate precipitation test: in 5 mL of2% sample solution, add 5 mL dilute hydrochloric acid solution (TS-117), further add 5 mL of water plus 2 mL of 10% potassium dichromate solution and 2ml. This should form an orange precipitate. Take 75 mg of cobalt nitrate and 300 mg of ammonium thiocyanate for being dissolved in 2ml of water; add 5 mL of 2% aqueous sample solution; after the mixing, add dilute hydrochloric acid test solution (TS-117) for acidification. This should form light blue precipitate. Take 5 mL of 2% sample solution; add 1 mL of 25% hydrochloric acid, 5 mL of 5% barium chloride and 1 mL 5% molybdenum tungsten phosphoric acid solution. This should generate a lot of white precipitate which gradually turns blue in the sunlight. The pH value of 5% sample solution should be 3.0 to 3.7. This is measured by conventional means. Adding a few drops of iodine test solution (TS-124) to 5 mL of 0.5% sample solution should produce a deep red color. Take 1 g of sample, add water to 10 ml as a suspension, add 0.1 mL of iodine test solution (TS-124), after mixing by shaking for 30s, iodine test solution should fade (to distinguish polyvinylpyrrolidone due to that polyvinylpyrrolidone can form red color). Add 1 mL of starch test solution (TS-235), after shaking and mixing, there should be no blue color formed. to produce blue. Content Analysis Estimated from the nitrogen content according to the following index of quality. Toxicity ADI 0~50 (FAO/WHO, 2001) LD50> 100g/kg (rat, oral). ADI does not make special provision (FAO/WHO, 2001). It is safe for food (FDA, §121.1110, §173.50, 2000). LD50:12g/kg (mice, abdominal injection). Limited use GB 2760-1996: beer GMP. Chemical Properties It is the cross-linked homopolymer of pure vinylpyrrolidone. It is hygroscopic and free-flowing white or off-white powder. It has a slight foul smell. It is insoluble in common solvents such as water, ethanol and ether. So its molecule weight range can't be measured. However, PVP has ability to form complex with various kinds of substances (such as "Hu" class substance which can lead to the discoloration of a variety of wines and beverages discoloration). Also it is easily to be removed after filtration because of its insolubility. Uses Clarifying agent; pigment stabilizer; colloidal stabilizer; It is mainly used for beer clarifying and quality stabilizing (reference amount 8~20g/100L, maintained for 24h and remove it by filtration), and can also be applied in combination with enzymes (protease) and protein adsorbents. It is also used to clarify the wine and as a stabilizer to prevent discoloration (reference amount 24~72g/100L). Clarifying agents; stabilizers; thickeners agent; tablet fillers; dispersants; PVP of molecular weight 360,000 are often used as the clarifying agent of beer, vinegar, and grape wine. Used as the fixing liquid for gas chromatography. It is used as a colloidal stabilizer and clarifying agent for beer clarification. Apply proper amount according the demands of production. It can be used for pharmacy, aquaculture, and livestock disinfectant for the sterilization of the skin and mucous. PolyFilterTM molecule has an amide bond for absorbing the hydroxyl groups located in polyphenol molecule to form hydrogen bonds, and therefore, can be used as the stabilizer of beer, fruit wine/grape wine, and drinking wine to extend their shelf life and improve the transparency, color and taste. The products have two specifications: disposable type and regeneration type. Disposable products are suitable for application by SMEs; renewable products demand the purchase of special filtration equipment; but since it is recyclable, it is suitable for large breweries for recycle application. In daily cosmetics, PVP and its copolymer has good dispersion property and filming property, and thus being able to be used as a setting lotion, hair spray and styling mousse, as opacifiers for hair care agents, as the stabilizer of shampoo foam, as wave styling agent and as the dispersants and affinity agents in hair dye. Adding PVP to cream, sunscreen, and hair removal agent can enhance wetting and lubricating effect. Taking advantage of the excellent properties of PVP such as surface activity, film-forming and non-irritating to the skin, no allergic reactions, etc., has broad prospects in its application in hair care and skin care products. Production method Its crude product comes from the polymerization of vinylpyrrolidone under basic catalyst or the existence of N, N'-divinyl amidine and further cross-inking reaction. Then use water, 5% acetic acid and 50% ethanol for reflux to until extract ≤50mg/kg (for over 3h). The 30% to 60% aqueous solution of the purified 1-vinyl-2-pyrrolidone, in the presence of ammonia or amines and also with hydrogen peroxide as the catalyst, has cross-linking and homo-polymerization reaction at a temperature of 50 °C and subject to further purification to obtain the final product. Chemical Properties Hygroscopic, white or yellowish-white powder or flakes. Chemical Properties Povidone occurs as a fine, white to creamy-white colored, odorless or almost odorless, hygroscopic powder. Povidones with K-values equal to or lower than 30 are manufactured by spray-drying and occur as spheres. Povidone K-90 and higher K-value povidones are manufactured by drum drying and occur as plates. Uses suitable for gene delivery Definition ChEBI: A vinyl polymer composed of repeating -CH2-CR- units where R is a 2-oxopyrrolidin-1-yl group. Production Methods Povidone is manufactured by the Reppe process. Acetylene and formaldehyde are reacted in the presence of a highly active copper acetylide catalyst to form butynediol, which is hydrogenated to butanediol and then cyclodehydrogenated to form butyrolactone. Pyrrolidone is produced by reacting butyrolactone with ammonia. This is followed by a vinylation reaction in which pyrrolidone and acetylene are reacted under pressure. The monomer, vinylpyrrolidone, is then polymerized in the presence of a combination of catalysts to produce povidone. brand name Kollidon CL (BASF); Kollidon CLM (BASF); Polyplasdone (International Specialty Products);Acu-dyne;Adapettes;Adsorbobase;Adsovbotear;Agent at 717;Albigen a;Aldacol q;Amiorel eritro;Amyderm s;Andrestrac 2-10;Anexa;B 7509;Betaisod;Bridine;Clinidine;Final step;Frepp/sepp;Ganex p 804;Ga-pvp-101;Gyno-bidex;Isoplasma;Jodoplex;K 115;Kollidon 17;Kollidon 25;Kollidon 30;Kollidon 90;Kollidon ce 50/50;Kollidon k 25;Kollidon k 30;Luviskol k 17;Luviskol k 25;Luviskol k 30;Luviskol k 90;Luvisteol;Medicort;Molycu;Mundidon;Neojodin;Oftan flurekain;Peragal st;Periston-n-toxobin;Pevidine;Plasmadone;Plasmoid;Plassint;Podiodine;Polyclar at;Polyclar h;Polyclar l;Polyplasdone xl;Polyvidone-escupient;Polyvinyl pyrrolidone;Povadyne;Povidone k 29-32;Pvp 50;Pvp0;Pvp-k 15;Pvp-k 25;Pvp-k 30;Pvp-k 60;Pvp-k 90;Pvp-macrose;Pvp-macrox;Rocmuth;Sd 13;Soft-care;Tears plus;Venostasin retard;Vetedine;Yodiplexin. World Health Organization (WHO) Polyvidone, a polymer of vinylpyrrolidinone, is an excipient used as a suspending and dispersing agent. Injectable preparations containing polymers with a molecular weight in the order of 12,000 have caused painful local granulomatous lesions. This has led to the withdrawal of polyvidone from such preparations in some countries. Polyvidone was formerly also used as a plasma expander but, because it was sequestered within the liver and spleen, this use has been discontinued. However, it remains widely used as a vehicle for ophthalmic preparations, and as the major component of artificial tears. General Description White powder. Compatible with a wide range of hydrophilic and hydrophobic resins. Air & Water Reactions Hygroscopic. Water soluble. Reactivity Profile Polyvinylpyrrolidone is a polymeric material and probably has low reactivity. Polyvinylpyrrolidone reacts as a weak base. Hazard Questionable carcinogen. Health Hazard SYMPTOMS: Polyvinylpyrrolidone may cause interstitial fibrosis in the lungs. Lesions regress when patient is no longer being exposed to the compound. Fire Hazard Flash point data for Polyvinylpyrrolidone are not available, but Polyvinylpyrrolidone is probably non-flammable. Pharmaceutical Applications Although povidone is used in a variety of pharmaceutical formulations, it is primarily used in solid-dosage forms. In tableting, povidone solutions are used as binders in wet-granulation processes.Povidone is also added to powder blends in the dry form and granulated in situ by the addition of water, alcohol, or hydroalcoholic solutions. Povidone is used as a solubilizer in oral and parenteral formulations, and has been shown to enhance dissolution of poorly soluble drugs from solid-dosage forms. Povidone solutions may also be used as coating agents or as binders when coating active pharmaceutical ingredients on a support such as sugar beads. Povidone is additionally used as a suspending, stabilizing, or viscosity-increasing agent in a number of topical and oral suspensions and solutions. The solubility of a number of poorly soluble active drugs may be increased by mixing with povidone. Special grades of pyrogen-free povidone are available and have been used in parenteral formulations; Contact allergens Polyvinylpyrrolidone is widely used as is in cosmetics such as hair care products and in medical products. It acts as iodophor in iodine-polyvinylpyrrolidone. PVP is an irritant and has been claimed as the allergen in some cases of dermatitis from iodine-polyvinylpyrrolidone (although iodine is more likely the hapten). It may cause type I contact urticaria or anaphylaxis. Safety Profile Mtldly toxic by intraperitoneal and intravenous routes. Questionable carcinogen. When heated to decomposition it emits toxic fumes of NOx. Safety Povidone has been used in pharmaceutical formulations for many years, being first used in the 1940s as a plasma expander, although it has now been superseded for this purpose by dextran. Povidone is widely used as an excipient, particularly in oral tablets and solutions. When consumed orally, povidone may be regarded as essentially nontoxic since it is not absorbed from the gastrointestinal tract or mucous membranes.Povidone additionally has no irritant effect on the skin and causes no sensitization. exists that povidone may accumulate in the organs of the body following intramuscular injection. A temporary acceptable daily intake for povidone has been set by the WHO at up to 25 mg/kg body-weight. (mouse, IP): 12 g/kg storage Povidone darkens to some extent on heating at 150°C, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-130°C; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place. Purification Methods Purify it by dialysis, and freeze-drying. Also by precipitation from CHCl3 solution by pouring into ether. Dry it in a vacuum over P2O5. For the crosslinked polymer purification is by boiling for 10minutes in 10% HCl and then washing with glass-distilled water until free from Cl ions. Finally, Cl ions are removed more readily by neutralising with KOH and continued washing. Incompatibilities Povidone is compatible in solution with a wide range of inorganic salts, natural and synthetic resins, and other chemicals. It forms molecular adducts in solution with sulfathiazole, sodium salicylate, salicylic acid, phenobarbital, tannin, and other compounds; see Section 18. The efficacy of some preservatives, e.g. thimerosal, may be adversely affected by the formation of complexes with povidone. Traditional High-Efficient Rheology Modifier Carbomer Efficient Rheology Modifier For Home Care Traditional Long-Flow Property Carbomer Improved Type - Easy To Disperse Carbomer Improved Type -Self-Wetting Carbomer Improved Type Carbomer Liquid Carbomer Pharmaceutical Grade Carbomer Home Care Carbomer High Carlity Traditional Carbomer Benzen Free Carbomer Homopolymer Of Vinylpyrrolidone NM-PVP K-30 Chemical Name: Homopolymer of Vinylpyrrolidone CTFA Name :Polyvinylpyrrolidone NM-PVP K-30 can dissolve in water and grain alcohol, isopropyl alcohol or chloroform, but not in acetone or diethyl ether. Have good absorption moisture, film-forming, complex ability. It is a high performance, versatile polymer widely used in pharmaceutical field, cosmetics field, beer, water treatment membrane, detergents, paints and other fields. Application 1. Pharma application: Used as binder for tablet and pellet, dissolving assistant for injection, flowing assistant capsule, dispersant for liquid medicine and pigment, stabilizer for enzyme and heat sensitive drug. 2. Cosmetic application: Used extensively in a wide range hair care, skin care &oral care products. The products are particularly suitable for formulation where viscosity modification and film forming properties are required. 3. Tech application: As surface coating agent, dispersing agent, thickener, binder, porogen in water treatment membrane ( hollow fiber m

PVP/VA Copolymer; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); Polectron 845; Luviskol VA 28I; Vinyl acetate-vinylpyrrolidone polymer; Vinylpyrrolidinone-vinyl acetate polymer CAS NO: 25086-89-9

Polyvinylpyrrolidone ;‘Plasdone’, PVP, Polyvidone, Povidone; POLYVINYLPYRROLIDONE K 90 cas no:9003-39-8

Povidone-Iodine is an iodophor solution containing a water-soluble complex of iodine and PVP K-90 (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells.Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function. WHEN GIVEN PARENTERALLY, UNEXCRETED PARTICLES ARE PHAGOCYTIZED BY CELLS OF RETICULOENDOTHELIAL SYSTEM & DEPOSITED IN STORAGE SITES IN LIVER, SPLEEN, LUNG, BONE MARROW...In 12 nonpregnant women, total iodine, protein-bound iodine, inorganic iodine, and thyroxine values were measured in serum before and 15, 30, 45 or 60 minutes after a two-minute vaginal disinfection with povidone-iodine (Betadine). Only 15 minutes after application, serum iodine levels were raised and remained significantly elevated 30, 45 and 60 minutes after disinfection. Serum concentrations of total iodine and inorganic iodine were increased up to fivefold to 15-fold, respectively; during the relative short period of observation, thyroxine levels were not altered.The disposition of N-[14C]-vinyl-2-pyrrolidone has been studied in male Sprague-Dawley rats following a single iv injection. ...Up to 6 hr after dosing, the highest tissue concentrations of radioactivity were found in the liver and small intestines. By that time, about 19% of the dose had been excreted in bile, yet, by 12 hr, only about 0.4% had been excreted in feces while about 75% had been excreted in urine. Thus, there appeared to be substantial enterohepatic recirculation of biliary metabolites. Very small quantities of the administered material were excreted unchanged. In a single rat, 12% of the urinary radioactivity was present as acetic acid. Other metabolites were not identified.Following ingestion /1-vinyl-2-pyrrolidinone/ is mainly distributed in the liver and small intestine. It is partially excreted in the urine in an acetate form, but it is mostly (88%) combined with water-soluble acid compounds. Following iv injection, 14C-1-vinyl-2-pyrrolidinone was cleared from the blood with a half-life of about 2 hr. Unchanged /1-vinyl-2-pyrrolidinone/ accounted for <0.6% of the dose administered.The disposition of N-[14C-vinyl]-2-pyrrolidinone was studied in male Sprague-Dawley rats following a single iv injection. Plasma levels of the intact compound dropped rapidly within the first 6 hours after dosing... . Urinary excretion by 12 hours represented 74.9% of a 5 microCi dose while 18.7% was excreted into the bile by 6 hours. 14C-activity attributed to the intact compound was found to be <0.59% of the dose in the urine and <0.46% in the bile. Tissue distribution studies showed that the liver and small intestines and contents contained the highest accumulation of 14C-activity up to 6 hours after administration of N-[14C-vinyl]-2-pyrrolidinone. Urine analyses performed for metabolite elucidation indicated that 12% of the radioactivity dosed was incorporated into acetate and the major remaining portion in species which appeared to be water soluble acidic compounds.The toxic effects of vinylpyrrolidone /and/ vinylacetate (VP-VA) were examined in rats. Female Wistar-rats, under ether narcosis, were given endotracheally 0.5 mL of a standard solution of VP-VA (10 g in 15 mL of physiological sodium-chloride solution). Other rats received up to 7 times the 2 mL standard solution daily under the skin of the back; between 1.1 and 45.0 g/kg VP-VA were injected. The animals were sacrificed between 1 and 365 days following the application of the VP-VA solution. Tissues were stained and examined by electron microscopy. One to 2 days after endotracheal injection, the alveoli were closely packed with macrophages. Four to 6 months after the last injection, there was still VP-VA in the lungs with the attendent macrophages. Animals killed 1 yr after the last injection showed no VP-VA in the lungs. After sc injection, most of the VP-VA was stored in the spleen. There were occasional, large macrophages found in the interstitial tissue of the lung. During the 1 yr period of observation, there was no evidence of tumors or systemic disease.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films. Povidone-Iodine is an iodophor solution containing a water-soluble complex of iodine and PVP K-90 (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells.Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function. WHEN GIVEN PARENTERALLY, UNEXCRETED PARTICLES ARE PHAGOCYTIZED BY CELLS OF RETICULOENDOTHELIAL SYSTEM & DEPOSITED IN STORAGE SITES IN LIVER, SPLEEN, LUNG, BONE MARROW...In 12 nonpregnant women, total iodine, protein-bound iodine, inorganic iodine, and thyroxine values were measured in serum before and 15, 30, 45 or 60 minutes after a two-minute vaginal disinfection with povidone-iodine (Betadine). Only 15 minutes after application, serum iodine levels were raised and remained significantly elevated 30, 45 and 60 minutes after disinfection. Serum concentrations of total iodine and inorganic iodine were increased up to fivefold to 15-fold, respectively; during the relative short period of observation, thyroxine levels were not altered.The disposition of N-[14C]-vinyl-2-pyrrolidone has been studied in male Sprague-Dawley rats following a single iv injection. ...Up to 6 hr after dosing, the highest tissue concentrations of radioactivity were found in the liver and small intestines. By that time, about 19% of the dose had been excreted in bile, yet, by 12 hr, only about 0.4% had been excreted in feces while about 75% had been excreted in urine. Thus, there appeared to be substantial enterohepatic recirculation of biliary metabolites. Very small quantities of the administered material were excreted unchanged. In a single rat, 12% of the urinary radioactivity was present as acetic acid. Other metabolites were not identified.Following ingestion /1-vinyl-2-pyrrolidinone/ is mainly distributed in the liver and small intestine. It is partially excreted in the urine in an acetate form, but it is mostly (88%) combined with water-soluble acid compounds. Following iv injection, 14C-1-vinyl-2-pyrrolidinone was cleared from the blood with a half-life of about 2 hr. Unchanged /1-vinyl-2-pyrrolidinone/ accounted for <0.6% of the dose administered.The disposition of N-[14C-vinyl]-2-pyrrolidinone was studied in male Sprague-Dawley rats following a single iv injection. Plasma levels of the intact compound dropped rapidly within the first 6 hours after dosing... . Urinary excretion by 12 hours represented 74.9% of a 5 microCi dose while 18.7% was excreted into the bile by 6 hours. 14C-activity attributed to the intact compound was found to be <0.59% of the dose in the urine and <0.46% in the bile. Tissue distribution studies showed that the liver and small intestines and contents contained the highest accumulation of 14C-activity up to 6 hours after administration of N-[14C-vinyl]-2-pyrrolidinone. Urine analyses performed for metabolite elucidation indicated that 12% of the radioactivity dosed was incorporated into acetate and the major remaining portion in species which appeared to be water soluble acidic compounds.The toxic effects of vinylpyrrolidone /and/ vinylacetate (VP-VA) were examined in rats. Female Wistar-rats, under ether narcosis, were given endotracheally 0.5 mL of a standard solution of VP-VA (10 g in 15 mL of physiological sodium-chloride solution). Other rats received up to 7 times the 2 mL standard solution daily under the skin of the back; between 1.1 and 45.0 g/kg VP-VA were injected. The animals were sacrificed between 1 and 365 days following the application of the VP-VA solution. Tissues were stained and examined by electron microscopy. One to 2 days after endotracheal injection, the alveoli were closely packed with macrophages. Four to 6 months after the last injection, there was still VP-VA in the lungs with the attendent macrophages. Animals killed 1 yr after the last injection showed no VP-VA in the lungs. After sc injection, most of the VP-VA was stored in the spleen. There were occasional, large macrophages found in the interstitial tissue of the lung. During the 1 yr period of observation, there was no evidence of tumors or systemic disease.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.

PVP VA 64 представляет собой линейный статистический сополимер 6:4 N-винилпирролидона и винилацетата.
Винилацетатный компонент ПВП ВА 64 снижает гидрофильность и температуру стеклования (Tg) по сравнению с гомополимерами повидона аналогичной молекулярной массы.
В результате, PVP VA 64 является превосходным связующим для таблеток, обладающим отличными адгезивными свойствами при влажной грануляции, а также при сухой грануляции и прямом прессовании.

КАС: 25086-89-9
МФ: C10H15NO3
МВт: 197,23

Благодаря своей сферической, полой морфологии частиц и высокой пластичности, PVP VA 64 исключительно хорошо работает в качестве вяжущего для прямого прессования.
Кроме того, более низкая Tg делает PVP VA 64 идеальной полимерной матрицей для твердых дисперсий/растворов посредством экструзии горячего расплава, что улучшает растворение плохо растворимых активных лекарственных веществ.
PVP VA 64 широко используется в фармацевтических препаратах и обычно считается нетоксичным.
Однако PVP VA 64 умеренно токсичен при приеме внутрь, вызывая желудочные расстройства.
PVP VA 64 не оказывает раздражающего или сенсибилизирующего действия на кожу.

Было проведено исследование канцерогенности и хронической токсичности PVP VA 64 (Kollidon VA 64) у крыс Wistar и собак породы бигль.
Результаты этих исследований продемонстрировали отсутствие каких-либо значимых токсикологических данных о высоких уровнях коподивона в пище у крыс и собак, что привело к ненаблюдаемым побочным эффектам в дозах 2800 мг/кг массы тела/день у крыс и 2500 мг/кг массы тела.

Сополимер ПВП ВА 64 выполняет функции связующего, пленкообразователя и фиксатора волос в косметических продуктах.
PVP VA 64 является более важным ингредиентом в рецептуре, чем с точки зрения ухода за кожей.
В качестве связующего агента PVP VA 64 помогает связать или скрепить вместе ингредиенты косметического продукта в форме прессованной лепешки или таблетки продукта.

Ингредиенты в сухой форме смешиваются с использованием минимального количества связующего, а затем прессуются до желаемого эффекта.
Этот метод предотвращает разрушение других ингредиентов продукта.
В качестве пленкообразователя при нанесении на волосы или кожу они образуют непрерывный, сцепляющийся, эластичный слой.

Этот слой/пленка обладает водоудерживающими свойствами, которые делают кожу гладкой и шелковистой. PVP VA 64 также используется в лаках и гелях для волос.
При использовании PVP VA 64 образует тонкий слой или пленку на поверхности волос.
Учитывая его структуру, PVP VA 64 также имеет несколько химических групп, образующих временные связи, которые не только помогают образовывать пленку, но и помогают прикрепляться к стержню волоса и поддерживать прическу.
PVP VA 64 предотвращает впитывание влаги волосами и помогает сохранить стиль.
PVP VA 64 используется в рецептурах средств для укладки и других средств по уходу за волосами.

Преимущества:
Пригодность для использования в прямом прессовании, сухой грануляции, влажной грануляции, экструзии горячего расплава и пленочном покрытии,
Хорошая текучесть,
Большая площадь поверхности благодаря полой морфологии частиц – улучшает сцепление частиц и хорошую сжимаемость,
Идеальная температура стеклования (Tg) для экструзии горячего расплава.

Химические свойства ПВП ВА 64
Плотность: 1,27 г/мл при 25 °C (лит.)
Показатель преломления: от 1,4300 до 1,4380
Fp: 72 ° F
Растворимость: растворимость более 10% в 1,4-бутандиоле, глицерине, бутаноле, хлороформе, дихлорметане, этаноле (95%), глицерине, метаноле, полиэтиленгликоле 400, пропан-2-оле, пропаноле, пропиленгликоле и воде.
Растворимость менее 1% в циклогексане, диэтиловом эфире, жидком парафине и пентане.
Форма: порошок
Белый цвет
Стабильность: Стабильная. Горюч, особенно в порошкообразном виде. Несовместим с сильными окислителями, сильными восстановителями.
LogP: 0,370 (оценка)
Система регистрации веществ EPA: PVP VA 64 (25086-89-9)

ПВП ВА 64 представляет собой аморфный порошок от белого до желтовато-белого цвета.
PVP VA 64 обычно высушивают распылением с относительно мелкими частицами.
ПВП ВА 64 имеет слабый запах и слабый вкус.

Использование
PVP VA 64 представляет собой водорастворимый полимер, используемый для улучшения усвоения и загрузки лекарственными средствами различных фармацевтических препаратов, включая противозачаточные пластыри.

Основное сырье косметики используется для геля для волос, мусса, шампуня и т. д., а также поверхностно-активных веществ, медицины и других отраслей промышленности.
ПВП ВА 64 в основном используется в качестве водорастворимых клеев и сухих клеев в технологии грануляции и прямого таблетирования, в качестве пленкообразующих материалов в пленочных покрытиях и в качестве порообразующих материалов в ароматизаторах.
PVP VA 64 наносится на сахарное покрытие для предотвращения образования лепестков, а нижнее покрытие используется для предотвращения попадания влаги.

Продукты серии сополимеров PVP VA 64 в основном используются в качестве пленкообразователей и формообразователей в области косметики, особенно в продуктах серии лаков для волос, лаков для волос, муссов и шампуней.
Они играют важную роль в качестве пленкообразователей и средств для укладки волос.
Если их использовать вместе с ПВП К30, они усилят эффект от их использования.

Методы производства
ПВП ВА 64 получают радикальной полимеризацией винилпирролидона и винилацетата в соотношении 6:4.
Синтез проводят в органическом растворителе из-за нерастворимости винилацетата в воде.

Фармацевтические приложения
PVP VA 64 используется в качестве связующего для таблеток, пленкообразователя и как часть матричного материала, используемого в препаратах с контролируемым высвобождением.
При таблетировании PVP VA 64 можно использовать в качестве связующего для прямого прессования и в качестве связующего при влажной грануляции.
PVP VA 64 часто добавляют в растворы для покрытий в качестве пленкообразующего агента.
PVP VA 64 обеспечивает хорошую адгезию, эластичность и твердость и может использоваться в качестве барьера от влаги.

Синонимы
25086-89-9
Полектрон 845
Лувискол В.А. 28И
Лувискол В.А. 37Е
Лувискол В.А., 64
Колима 10
Колима 35
этенилацетат; 1-этенилпирролидин-2-он
Гантрон С 860
ПВП-ВА
Ганекс Е 535
ГАФ-С 630
Лувискол В.А. 281
Лувискол В.А. 28 И
Лувискол В.А. 37 Е
я 535
я 635
я 735
S 630
MFCD00134018
Лувискол ВА-64
SCHEMBL29127
Коповидон (технический сорт)
винилпирролидон/винилацетат
Винилпирролидон/винилацетат
N-винилпирролидон/винилацетат
1-винилпирролидонвинилацетат
BCP31918
NSC114023
NSC114024
НСК114025
NSC114026
АКОС015898247
НБК-114023
НСК-114024
НСК-114025
НБК-114026
1-этенилпирролидин-2-он; этенилацетат
этенилэтаноат; 1-этенилпирролидин-2-он
FT-0659810
А817635
этениловый эфир уксусной кислоты; 1-этенил-2-пирролидинон
733045-73-3

SYNONYMS acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone;ethenyl acetate;1-ethenylpyrrolidin-2-one;poly(1-vinyl pyrrolidone-co-vinyl acetate) CAS NO: 25086-89-9

Poly(1-vinylpyrrolidone-co-vinyl acetate); Copovidone; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); Vinyl acetate-vinylpyrrolidone copolymer; PVP/VA Copolymer; Vinyl acetate-vinylpyrrolidinone polymer; Vinylpyrrolidinone-vinyl acetate polymer;

PVP/VA I-535 (Polyvinylpyrrolidone Vinyl Acetate) VP/VA Copolymer. PVP-VA I-535 acts as a film forming agent. PVP-VA I-535 is produced by the free-radical polymerization of monomers in the ratio of 50/50 (VP/VA). Shows good propellant compatibility. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. PVP-VA I-535 finds application in formulating hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP-VA I-535 offers strong & stiff hold, enhanced high humidity curl retention. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer? PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) S copolymer PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) S-630 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W copolymers PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-735 copolymer, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-535 copolymer and PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E- 335 copolymer. In general, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymer is less hygroscopic than PVP. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) S-630 copolymer is used as a binder to allow the aqueous processing of photoresists. Storage and handling PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E- and I-series To fit more application areas, the E- and I-series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W copolymers PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-735, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-535 and PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-335. In general, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is less hygroscopic than PVP. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate), N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) used in industrial, specialty and imaging coatings, printing inks and paints. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.[1] What is PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer? PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E- and I-series To fit more application areas, the E- and I-series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-735, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W copolymers PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 is a 70/30 copolymer of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) and vinyl acetate supplied as a 50% solution in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-735, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-535 and PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-335. In general, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is less hygroscopic than PVP. Uses Medical PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an adhesive in glue stick and hot-melt adhesives PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an emulsifier and disintegrant for solution polymerization PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a thickening agent in tooth whitening gels[10] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is useful for making an aqueous mounting medium.[16] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) instead.[22][23] Properties of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) and its oxidized hydrolyzate. History of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. VP/VA Copolymer. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a film former. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is produced by the free-radical polymerization of monomers in the ratio of 70/30 (VP/VA). PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) copolymer in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers

Saç jölesi ve spreylerinde sertleştirici polimer. Saç jölesi (%10-15), Spreylerde (%8-20)

PVP/VA W-635 VP/VA Copolymer. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a film former. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is produced by the free-radical polymerization of monomers in the ratio of 70/30 (VP/VA). PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) copolymer in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer? PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) S copolymer PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) S-630 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W copolymers PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-735 copolymer, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-535 copolymer and PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E- 335 copolymer. In general, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymer is less hygroscopic than PVP. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) S-630 copolymer is used as a binder to allow the aqueous processing of photoresists. Storage and handling PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E- and I-series To fit more application areas, the E- and I-series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W copolymers PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-735, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-535 and PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-335. In general, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is less hygroscopic than PVP. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) used in industrial, specialty and imaging coatings, printing inks and paints. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.[1] What is PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer? PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E- and I-series To fit more application areas, the E- and I-series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-735, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W copolymers PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 is a 70/30 copolymer of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) and vinyl acetate supplied as a 50% solution in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-735, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-535 and PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-335. In general, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is less hygroscopic than PVP. Uses Medical PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an adhesive in glue stick and hot-melt adhesives PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an emulsifier and disintegrant for solution polymerization PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a thickening agent in tooth whitening gels[10] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is useful for making an aqueous mounting medium.[16] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) instead.[22][23] Properties of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) and its oxidized hydrolyzate. History of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production.

PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate) VP/VA Copolymer. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is a film former. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is produced by the free-radical polymerization of monomers in the ratio of 70/30 (VP/VA). PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) copolymer in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer? PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) S copolymer PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) S-630 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W copolymers PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-735 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-735 copolymer, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-535 copolymer and PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E- 335 copolymer. In general, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymer is less hygroscopic than PVP. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) S-630 copolymer is used as a binder to allow the aqueous processing of photoresists. Storage and handling PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E- and I-series To fit more application areas, the E- and I-series of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W copolymers PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-735 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-735, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-535 and PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-335. In general, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is less hygroscopic than PVP. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat), N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) used in industrial, specialty and imaging coatings, printing inks and paints. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.[1] What is PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer? PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E- and I-series To fit more application areas, the E- and I-series of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-735, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W copolymers PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-735 is a 70/30 copolymer of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) and vinyl acetate supplied as a 50% solution in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-735 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-735, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-535 and PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-335. In general, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is less hygroscopic than PVP. Uses Medical PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as an adhesive in glue stick and hot-melt adhesives PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as an emulsifier and disintegrant for solution polymerization PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a thickening agent in tooth whitening gels[10] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is useful for making an aqueous mounting medium.[16] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) component of the solution.[19] A woman, who had previ

PYRIDOXINE HCL, N° CAS : 58-56-0 / 12001-77-3 - Pyridoxine hydrochloride. Nom INCI : PYRIDOXINE HCL. Nom chimique : 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride, N° EINECS/ELINCS : 200-386-2 / -. Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Agent d'entretien de la peau : Maintient la peau en bon état

cas no 9003-39-8 PVP, Polyvidone, Povidone;

Plasdone’, PVP, Polyvidone, Povidone CAS # : 9003-39-8

PYRIDINE-TRIPHENYLBORANE COMPLEX; Pyridine-triphenylborane; Pyridine-triPhenylborate; Pyridine-triphenylborane(1/1); Pyridine-triphenylbo; Triphenyl(pyridin-1-iuM-1-yl)borate; T6NJ &RBR&R; Boron,triphenyl(pyridine)-, (T-4)- CAS NO:971-66-4

DISODIUM PYROPHOSPHATE, N° CAS : 7758-16-9 - Pyrophosphate disodique. Origine(s) : Synthétique. Nom INCI : DISODIUM PYROPHOSPHATE. N° EINECS/ELINCS : 231-835-0. Le pyrophosphate disodique se présente sous la forme d'une poudre cristalline blanche. Dans les cosmétiques, on s'en sert d'agent tampon, de chélateur et d'anti-corrosif. Ses fonctions (INCI): Anticorrosif : Empêche la corrosion de l'emballage Régulateur de pH : Stabilise le pH des cosmétiques Agent de chélation : Réagit et forme des complexes avec des ions métalliques qui pourraient affecter la stabilité et / ou l'apparence des produits cosmétiques

Pyridoxol hydrochloride; Vitamin B6 hydrochloride; Deamine Hydrochloride; 5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride; Pyridoxinium chloride; Adermine hydrochloride; Hexabione hydrochloride; 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine hydrochloride; 5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride; Pyridoxyl hydrochloride; 3-Hydroxy-4,5-dimethylol-a-picoline hydrochloride; Bonasanit; Pyridipea cas no:58-56-0

Poly(1-vinylpyrrolidone-co-vinyl acetate); Copovidone; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); Vinyl acetate-vinylpyrrolidone copolymer; PVP/VA Copolymer; Vinyl acetate-vinylpyrrolidinone polymer; Vinylpyrrolidinone-vinyl acetate polymer;

219-574-0 [EINECS]; 2466-09-3 [RN]; Acide diphosphorique [French] [ACD/IUPAC Name]; Diphosphoric acid ; Diphosphorsäure [German] [ACD/IUPAC Name]; hydrogen pyrophosphate; MFCD00011343 [MDL number]; phosphoric anhydride; Pyrophosphic acid; Pyrophosphoric Acid; (phosphonooxy)phosphonic acid [2466-09-3] 03.09.2466 1314-56-3 [RN] 14000-31-8 [RN] 2-(5-Chloro-2-methoxyphenyl)pyrrolidine [ACD/IUPAC Name] 2',3'-Dideoxycytidine 5'-triphosphate 215-236-1 [EINECS] 2'-Deoxyadenosine 5'-triphosphate 33943-49-6 [RN] 3-methylbut-3-enyl trihydrogen diphosphate 69639-93-6 [RN] 7722-88-5 [RN] ADENOSINE-5'-DIPHOSPHATE Adenosine-5'-triphosphate ADP ATP CTP CYTIDINE-5'-TRIPHOSPHATE dCt dimethylallyl diphosphate Diphosphorsaeure DMA DPO DTP IPE MFCD02663458 [MDL number] Oxy-1,1-diphosphonic acid phosphono dihydrogen phosphate Phosphonooxyphosphonic acid Phosphoricanhydride Phosphotex POP PPV Pyrophosphoricacid Pyrophosphorsaeure THYMIDINE-5'-TRIPHOSPHATE TTP μ-oxido-bis(dihydroxidooxidophosphorus) 焦磷酸 [Chinese]

PYRUVIC ACID, N° CAS : 127-17-3, Nom INCI : PYRUVIC ACID, Nom chimique : Propanoic Acid, 2-oxo, N° EINECS/ELINCS : 204-824-3. Ses fonctions (INCI). Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit

pyrus communis flower extract; extract of the flowers of the pear, pyrus communis l., rosaceae; european pear flower extract CAS NO:90082-43-2

Quartemine; 1-Hexadecanaminium, N,N,N-trimethyl-, chloride cas no: 112-02-7

ОПИСАНИЕ:

П-бензохинон, парахинон, представляет собой химическое соединение с формулой C6H4O2.
В чистом виде п-бензохинон образует ярко-желтые кристаллы с характерным раздражающим запахом, напоминающим запах хлора, отбеливателя, горячего пластика или формальдегида.
Это шестичленное кольцевое соединение представляет собой окисленное производное 1,4-гидрохинона.


Номер CAS : 106-51-4
Номер ЕС : 203-405-2
Линейная формула: C6H4(=O)2

СИНОНИМ(Ы) П-БЕНЗОХИНОНА:
Хинон, 1,4-бензохинон[1];бензохинон;п-бензохинон;п-хинон


Молекула многофункциональна: П-бензохинон проявляет свойства кетона, способный образовывать оксимы; окислитель, образующий дигидроксипроизводное; и алкен, вступающий в реакции присоединения, особенно типичные для α,β-ненасыщенных кетонов.
П-бензохинон чувствителен как к сильным минеральным кислотам, так и к щелочам, которые вызывают конденсацию и разложение соединения.


P-Бензохинон используется в качестве диенофила в циклоприсоединениях Дильса-Альдера для получения нафтохинонов и 1,4-фенантрендионов.
П-бензохинон действует как реагент дегидрирования и окислитель в синтетической органической химии.
В реакции Тиле-Винтера он участвует в получении триацетата гидроксихинола путем взаимодействия с уксусным ангидридом и серной кислотой.

P-Бензохинон также используется в синтезе бромадола и для подавления миграции двойных связей во время реакций метатезиса олефинов.
P-Бензохинон используется в качестве предшественника гидрохинона, который находит применение в фотографии, а также в качестве восстановителя и антиоксиданта в производстве каучука.


п-Бензохинон (PBQ) представляет собой циклический сопряженный дикетон.
Сообщается о его фотоэлектронном спектре высокого разрешения.
Зарегистрированы и проанализированы видимые и ближние ультрафиолетовые спектры ПБХ.

Сообщалось, что его добавление в качестве соагента увеличивает скорость сшивания полипропилена, инициируемого пиролизом пероксидов.
Его влияние на гемоглобин (Hb) исследовано на основе иммуноблоттинга и масс-спектрального анализа крови курильщика.


ПРИГОТОВЛЕНИЕ Р-БЕНЗОХИНОНА:
1,4-Бензохинон получают промышленным путем окислением гидрохинона, который можно получить несколькими способами.
Один путь включает окисление диизопропилбензола и перегруппировку Хока.
Итоговую реакцию можно представить следующим образом:
C6H4(CHMe2)2 + 3 O2 → C6H4O2 + 2 OCMe2 + H2O

Реакция протекает через бис(гидропероксид) и гидрохинон.
Ацетон является побочным продуктом.
Другой важный процесс включает прямое гидроксилирование фенола кислой перекисью водорода: C6H5OH + H2O2 → C6H4(OH)2 + H2O. Образуются как гидрохинон, так и катехол.

Последующее окисление гидрохинона дает хинон.[8]
Хинон первоначально получали промышленным путем окислением анилина, например, диоксидом марганца.
Этот метод в основном практикуется в КНР, где экологические нормы более смягчены.

Окисление гидрохинона протекает легко.
В одном из таких методов в качестве окислителя используется перекись водорода, а в качестве катализатора окисления, происходящего в полярном растворителе, - йод или соль йода; например, изопропиловый спирт.
При нагревании почти до точки плавления 1,4-бензохинон сублимируется даже при атмосферном давлении, что обеспечивает эффективную очистку.
Нечистые образцы часто имеют темный цвет из-за присутствия хингидрона, темно-зеленого комплекса хинона с гидрохиноном с переносом заряда 1:1.

СТРУКТУРА И РЕДОКС P-БЕНЗОХИНОНА:
Расстояния связей C–C и C–O в бензохиноне (Q), его 1e восстановленном производном (Q-) и гидрохиноне (H2Q).
Бензохинон представляет собой плоскую молекулу с локализованными чередующимися связями C=C, C=O и C–C.
Восстановление дает семихиноновый анион C6H4O2-}, который принимает более делокализованную структуру.
Дальнейшее восстановление в сочетании с протонированием дает гидрохинон, в котором кольцо C6 полностью делокализовано.


РЕАКЦИИ И ПРИМЕНЕНИЕ Р-БЕНЗОХИНОНА:
Хинон в основном используется в качестве предшественника гидрохинона, который используется в фотографии и производстве резины в качестве восстановителя и антиоксиданта.
Бензохиноний — релаксант скелетных мышц, блокатор ганглиев, изготовленный из бензохинона.


ОРГАНИЧЕСКИЙ СИНТЕЗ Р-БЕНЗОХИНОНА:
П-бензохинон используется в качестве акцептора водорода и окислителя в органическом синтезе.
1,4-Бензохинон служит реагентом дегидрирования.
P-Бензохинон также используется в качестве диенофила в реакциях Дильса-Альдера.


Бензохинон реагирует с уксусным ангидридом и серной кислотой с образованием триацетата гидроксихинола.
Эта реакция называется реакцией Тиле или реакцией Тиле-Винтера[19][20] в честь Иоганна Тиле, который впервые описал ее в 1898 году, и в честь Эрнста Винтера, который дополнительно описал механизм ее реакции в 1900 году.

На этом этапе полного синтеза метахромина А находит применение:
Бензохинон также используется для подавления миграции двойной связи во время реакций метатезиса олефинов.
Кислый раствор йодида калия восстанавливает раствор бензохинона до гидрохинона, который можно повторно окислить до хинона раствором нитрата серебра.
Благодаря своей способности действовать как окислитель, 1,4-бензохинон можно обнаружить в методах, использующих окисление Вакера-Цуджи, где соль палладия катализирует превращение алкена в кетон.

Эту реакцию обычно проводят с использованием кислорода под давлением в качестве окислителя, но иногда предпочтительным может быть бензохинон.
P-Бензохинон также используется в качестве реагента в некоторых вариантах окисления Вакера.
1,4-Бензохинон используется в синтезе Бромадола и родственных аналогов.


2,3-Дихлор-5,6-дициано-1,4-бензохинон (DDQ) является более сильным окислителем и агентом дегидрирования, чем 1,4-бензохинон.
Хлоранил 1,4-C6Cl4O2 является еще одним мощным окислителем и агентом дегидрирования.
Монохлор-п-бензохинон — еще один, но более мягкий окислитель.


МЕТАБОЛИЗМ Р-БЕНЗОХИНОНА:
1,4-Бензохинон — токсичный метаболит, обнаруженный в крови человека, и его можно использовать для отслеживания воздействия бензола или смесей, содержащих бензол и бензольные соединения, таких как бензин.
Соединение может влиять на клеточное дыхание, а у животных, подвергшихся серьезному воздействию, было обнаружено повреждение почек.
Он выводится из организма в исходной форме, а также в виде вариаций собственного метаболита гидрохинона.


ПРИМЕНЕНИЕ P-БЕНЗОХИНОНА:
п-Бензохинон может быть использован для образования производных бензофуранона при взаимодействии с анилидами β-аминокротоновых кислот по реакции Неницеску.
Диенофил используется в циклоприсоединениях Дильса-Альдера с образованием нафтохинонов и 1,4-фенантрендионов.

Окислитель, используемый на первой стадии синтеза более зеленого амина из концевых олефинов путем окисления Вакера с последующим переносным гидрированием полученного имина.




п-Бензохинон используется в качестве диенофила в циклоприсоединениях Дильса-Альдера для получения нафтохинонов и 1,4-фенантрендионов.
P-бензохинон действует как реагент дегидрирования и как окислитель в синтетической органической химии.

В реакции Тиле-Винтера он участвует в получении триацетата гидроксихинола путем взаимодействия с уксусным ангидридом и серной кислотой.
P-Бензохинон также используется при синтезе бромадола и для подавления миграции двойных связей во время реакций метатезиса олефинов.
P-Бензохинон используется в качестве предшественника гидрохинона, который находит применение в фотографии, а также в качестве восстановителя и антиоксиданта при производстве каучука.




ХИМИЧЕСКИЕ И ФИЗИЧЕСКИЕ СВОЙСТВА Р-БЕНЗОХИНОНА:
Химическая формула C6H4O2
Молярная масса 108,096 г•моль−1
Внешний вид Желтое твердое вещество
Запах Едкий, хлороподобный[2]
Плотность 1,318 г/см3 при 20 °C
Температура плавления 115 ° C (239 ° F; 388 К)
Точка кипения
Растворимость в воде 11 г/л (18 °C)
Растворимость Мало растворим в петролейном эфире; растворим в ацетоне; 10% в этаноле, бензоле, диэтиловом эфире
Давление пара 0,1 мм рт.ст. (25 °C)[2]
Магнитная восприимчивость (χ) -38,4•10-6 см3/моль
Количество CAS:
106-51-4
Молекулярная масса:
108.09
Байльштайн:
773967
Номер ЕС:
203-405-2
биологический источник
синтетический
Уровень качества
200
оценка
реагент
плотность пара
3,73 (по сравнению с воздухом)
давление газа
0,1 мм рт. ст. (25 °С)
анализ
≥98%
форма
порошок или кристаллы
температура самовоспламенения.
815 °Ф
более экологичные альтернативные характеристики продукта
Катализ
Узнайте больше о принципах зеленой химии.
депутат
113-115 °С (лит.)
растворимость
вода: растворим 14,7 г/л при 20 °C
более зеленая альтернативная категория
температура хранения.
комнатная температура
строка УЛЫБКИ
O=C1C=CC(=O)C=C1
ИнЧИ
1S/C6H4O2/c7-5-1-2-6(8)4-3-5/h1-4H
Ключ ИнЧИ
AZQWKYJCGOJGHM-UHFFFAOYSA-N
Генная информация
человек ... ACHE(43) , BCHE(590) , CES1(1066)

КАС
106-51-4
Молекулярная формула
C6H4O2
Молекулярные частицы (г/моль)
108.096
Число леев
MFCD00001591
Кле Инчи
AZQWKYJCGOJGHM-UHFFFAOYSA-NAfficher plus
Синоним
п-бензохинон, бензохинон, хинон, 1,4-бензохинон, п-хинон, хинон, 2,5-циклогексадиен-1,4-дион, циклогексадиендион, пара-хинон, 1,4-бензохинДобавить плюс
CID ПабХим
4650
ЧЭБИ
ЧЕБИ:16509
Номинал ИЮПАК
циклогекса-2,5-диен-1,4-дион
УЛЫБКИ
C1=CC(=O)C=CC1=O
Химическое название или материал п-бензохинон
Температура плавления от 112°C до 115°C.
Плотность 1,318
Температура кипения ~180°C (сублимация)
Температура вспышки 77°C (171°F)
Процентный диапазон дозировки ≥98%
Запах острый
Количество 100 г
Номер один UN2587
Байльштейн 773967
Чувствительность Светочувствительный
Индекс Мерк 14,8074
Информация о растворимости Растворим в воде, этаноле, эфире, метаноле, бензоле, ацетоне и этилацетате.
Формула веса 108,1
Процент чистоты ≥98%
Растворимость 10 г/л (25°C)
Температура плавления 110–113°С.
Молярная масса 108,09 г/моль
Объемная плотность 700 кг/м3
Температура кипения 180°C (сублимированный)
Давление пара 0,12 гПа (20°C)
Плотность 1,32 г/см3 (20°С)
pH 4 (1 г/л, H2O, 20°C)
Точка воспламенения 560°C




ИНФОРМАЦИЯ ПО БЕЗОПАСНОСТИ П-БЕНЗОХИНОНА:
Меры первой помощи:
Описание мер первой помощи:
Общий совет:
Проконсультируйтесь с врачом.
Покажите этот паспорт безопасности лечащему врачу.
Выйдите из опасной зоны:

При вдыхании:
При вдыхании выведите пострадавшего на свежий воздух.
Если нет дыхания проведите искусственную вентиляцию легких.
Проконсультируйтесь с врачом.
При попадании на кожу:
Немедленно снять загрязненную одежду и обувь.
Смыть большим количеством воды с мылом.
Проконсультируйтесь с врачом.

При попадании в глаза:
Тщательно промойте большим количеством воды в течение не менее 15 минут и обратитесь к врачу.
Продолжайте промывать глаза во время транспортировки в больницу.

При проглатывании:
Не вызывает рвоту.
Никогда не давайте ничего перорально человеку, находящемуся без сознания.
Прополоскать рот водой.
Проконсультируйтесь с врачом.

Противопожарные меры:
Средства пожаротушения:
Подходящие средства пожаротушения:
Используйте водяной спрей, спиртостойкую пену, сухие химикаты или углекислый газ.
Особые опасности, исходящие от вещества или смеси
Оксиды углерода, Оксиды азота (NOx), Газообразный хлористый водород

Совет пожарным:
При необходимости наденьте автономный дыхательный аппарат для тушения пожара.
Меры при случайном высвобождении:
Меры личной безопасности, защитное снаряжение и действия в чрезвычайных ситуациях
Используйте средства индивидуальной защиты.

Избегайте вдыхания паров, тумана или газа.
Эвакуируйте персонал в безопасные места.

Экологические меры предосторожности:
Предотвратите дальнейшую утечку или разлив, если это безопасно.
Не допускайте попадания продукта в канализацию.
Необходимо избегать попадания в окружающую среду.

Методы и материалы для локализации и очистки:
Промочить инертным абсорбирующим материалом и утилизировать как опасные отходы.
Хранить в подходящих закрытых контейнерах для утилизации.

Обращение и хранение:
Меры предосторожности для безопасного обращения:
Избегайте вдыхания паров или тумана.

Условия безопасного хранения, включая любые несовместимости:
Хранить контейнер плотно закрытым в сухом и хорошо проветриваемом месте.
Открытые контейнеры необходимо тщательно закрыть и хранить в вертикальном положении во избежание утечки.
Класс хранения (TRGS 510): 8А: Горючие, коррозионно-активные опасные материалы.

Контроль воздействия / личная защита:
Параметры управления:
Компоненты с параметрами контроля рабочего места
Не содержит веществ с предельно допустимыми значениями профессионального воздействия.
Средства контроля воздействия:
Соответствующие технические средства контроля:
Обращайтесь в соответствии с правилами промышленной гигиены и техники безопасности.
Мойте руки перед перерывами и в конце рабочего дня.

Средства индивидуальной защиты:
Защита глаз/лица:
Плотно прилегающие защитные очки.
Лицевой щиток (минимум 8 дюймов).
Используйте средства защиты глаз, протестированные и одобренные в соответствии с соответствующими государственными стандартами, такими как NIOSH (США) или EN 166 (ЕС).

Защита кожи:
Работайте в перчатках.
Перчатки необходимо проверять перед использованием.
Используйте подходящие перчатки
технику снятия (не касаясь внешней поверхности перчатки), чтобы избежать попадания продукта на кожу.
Утилизируйте загрязненные перчатки после использования в соответствии с действующим законодательством и надлежащей лабораторной практикой.
Вымойте и высушите руки.

Полный контакт:
Материал: Нитриловый каучук.
Минимальная толщина слоя: 0,11 мм.
Время прорыва: 480 мин.
Протестированный материал: Дерматрил (KCL 740 / Aldrich Z677272, размер M)
Всплеск контакта
Материал: Нитриловый каучук.
Минимальная толщина слоя: 0,11 мм.
Время прорыва: 480 мин.
Протестированный материал: Дерматрил (KCL 740 / Aldrich Z677272, размер M)
Его не следует истолковывать как разрешение на какой-либо конкретный сценарий использования.

Защита тела:
Полный костюм защиты от химикатов. Тип защитного средства необходимо выбирать в зависимости от концентрации и количества опасного вещества на конкретном рабочем месте.
Защита органов дыхания:
Если оценка риска показывает, что воздухоочистительные респираторы уместны, используйте полнолицевой респиратор с многоцелевыми комбинированными (США) или респираторными картриджами типа ABEK (EN 14387) в качестве резерва для инженерных средств контроля.

Если респиратор является единственным средством защиты, используйте респиратор, закрывающий все лицо.
Используйте респираторы и их компоненты, протестированные и одобренные в соответствии с соответствующими государственными стандартами, такими как NIOSH (США) или CEN (ЕС).
Контроль воздействия на окружающую среду
Предотвратите дальнейшую утечку или разлив, если это безопасно.
Не допускайте попадания продукта в канализацию.
Необходимо избегать попадания в окружающую среду.

Стабильность и химическая активность:
Химическая стабильность:
Стабилен при рекомендуемых условиях хранения.
Несовместимые материалы:
Сильные окислители:
Опасные продукты разложения:
Опасные продукты разложения образуются в условиях пожара.
Оксиды углерода, Оксиды азота (NOx), Газообразный хлористый водород.

Утилизация отходов:
Методы переработки отходов:
Продукт:
Предложите решения для излишков и неперерабатываемых отходов лицензированной компании по утилизации.
Обратитесь в лицензированную профессиональную службу по утилизации отходов, чтобы избавиться от этого материала.
Загрязненная упаковка:
Утилизируйте как неиспользованный продукт.

Yumuşatıcı (%6-10)

Quartemine; 1-Hexadecanaminium, N,N,N-trimethyl-, chloride cas no: 112-02-7

QUARTZ, N° CAS : 14808-60-7 - E551, Nom INCI : QUARTZ, N° EINECS/ELINCS : 238-878-4. Ses fonctions (INCI). Agent Abrasif : Enlève les matières présentes en surface du corps, aide à nettoyer les dents et améliore la brillance.

Didecyl Dimethyl Ammonium Carbonate; Didecyl Dimethyl Ammonium Bicarbonate; Carboquat™ H;

Coco-ethyldimonium ethosulfate; Quaternary ammonium compounds, coco alkyl ethyldimethyl, ethyl sulfates; Cocodimethylammonium diethyl sulfate;Cocodimethylethylammonium ethosulfate; Cocodimethylethylammonium, ethylsulfate; Dimethylcocoethylammonium, ethylsulfate; Ethyldimethylcocoammonium, ethyl sulfate; N,N-Dimethyl-N-ethyl-N-cocoammonium ethylsulfate CAS NO:68308-64-5

alkyl ethyl benzyl dimethyl ammonium chloride; Dodecyl(ethylbenzyl)dimethylammonium chloride; QUATERNIUM-14, N° CAS : 27479-28-3. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-14. Nom chimique : Dodecyl(ethylbenzyl)dimethylammonium chloride. N° EINECS/ELINCS : 248-486-5, Classification : Ammonium quaternaire. Ses fonctions (INCI). Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes; Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface; Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance; Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Noms français : AMMONIUM, DODECYL(AR-ETHYLBENZYL)DIMETHYL-, CHLORIDE; BENZENEMETHANAMINIUM, N-DODECYL-AR-ETHYL-N,N-DIMETHYL-, CHLORIDE; Chlorure de dodécyldiméthyl(éthylbenzyl)ammonium. Noms anglais : Dodecyldimethyl(ethylbenzyl)ammonium chloride. TETRADECYLDIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE; alkyl ethyl benzyl dimethyl ammonium chloride; benzenemethanaminium, N-dodecyl-ar-ethyl-N,N-dimethyl-, chloride; dodecyl (ethyl benzyl) dimethyl ammonium chloride; dodecyl dimethyl ethyl benzyl ammonium chloride; dodecyl dimethyl ethylbenzyl ammonium chloride; dodecyl-[(4-ethylphenyl)methyl]-dimethylazanium chloride; N- dodecyl-ar-ethyl-N,N-dimethylbenzenemethanaminium chloride; dodecyldimethyl(ethylbenzyl)ammonium chloride; quaternary ammonium compounds, C12-14-alkyl[(ethylphenyl)methyl]dimethyl, chloridesUtilisation et sources d'émission: Additif alimentaire, fabrication de cosmétiques. 273-318-2 [EINECS] 68956-79-6 [RN] Benzenemethanaminium, 4-ethyl-N,N-dimethyl-N-tetradecyl-, chloride (1:1) [ACD/Index Name] Chlorure de N-(4-éthylbenzyl)-N,N-diméthyl-1-tétradécanaminium [French] [ACD/IUPAC Name] DIMETHYL ETHYLBENZYL MYRISTYL AMMONIUM CHLORIDE N-(4-Ethylbenzyl)-N,N-dimethyl-1-tetradecanaminium chloride [ACD/IUPAC Name] N-(4-Ethylbenzyl)-N,N-dimethyl-1-tetradecanaminiumchlorid [German] [ACD/IUPAC Name] (4-ethylbenzyl)-dimethyl-myristyl-ammonium chloride (4-ethylbenzyl)-lauryl-dimethyl-ammonium chloride (4-ethylphenyl)methyl-dimethyl-tetradecylammonium chloride (4-ethylphenyl)methyl-dimethyl-tetradecyl-ammonium chloride (4-ethylphenyl)methyl-dimethyl-tetradecylazanium chloride (4-ethylphenyl)methyl-dimethyl-tetradecyl-azanium chloride [(4-ETHYLPHENYL)METHYL]DIMETHYLTETRADECYLAZANIUM CHLORIDE 27479-28-3 [RN] Benzenemethanaminium, N-dodecyl-ar-ethyl-N,N-dimethyl-, chloride Dodecyl dimethyl ethylbenzyl ammonium chloride dodecyl(ethylbenzyl)dimethylammonium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethylammonium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethyl-ammonium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethylazanium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethyl-azanium chloride DODECYLDIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE EINECS 248-486-5 N-[(4-Ethylphenyl)methyl]-N,N-dimethyltetradecan-1-aminium chloride N-ALKYL ETHYLBENZYL DIMETHYL AMMONIUM CHLORIDE (C12-C14) N-Dodecyl-ar-ethyl-N,N-dimethylbenzenemethanaminium chloride NOCAS_872364 Quaternary ammonium compounds, C12-18-alkyl[(ethylphenyl)methyl]dimethyl, chlorides QUATERNIUM-14 TETRADECYLDIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE alkyl ethyl benzyl dimethyl ammonium chloride benzenemethanaminium, N-dodecyl-ar-ethyl-N,N-dimethyl-, chloride dodecyl (ethyl benzyl) dimethyl ammonium chloride dodecyl dimethyl ethyl benzyl ammonium chloride dodecyl dimethyl ethylbenzyl ammonium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethylazanium chloride N- dodecyl-ar-ethyl-N,N-dimethylbenzenemethanaminium chloride dodecyldimethyl(ethylbenzyl)ammonium chloride quaternary ammonium compounds, C12-14-alkyl[(ethylphenyl)methyl]dimethyl, chlorides

QUATERNIUM-15, N° CAS : 4080-31-3 / 51229-78-8. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-15, Nom chimique : Methenamine 3-chloroallylochloride, N° EINECS/ELINCS : 223-805-0 / 426-020-3. Classification : Ammonium quaternaire, Règlementé, Libérateur de Formaldéhyde, Conservateur. Restriction en Europe : La concentration maximale autorisée dans les préparations cosmétiques prêtes à l'emploi est de 0,2 %. Interdit en Europe à partir du 12 juin 2019. Ses fonctions (INCI): Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétiques.Quaternium-15 (systematic name: hexamethylenetetramine chloroallyl chloride) is a quaternary ammonium salt used as a surfactant and preservative in many cosmetics and industrial substances. It acts as an antimicrobial agent because it acts as a formaldehyde releaser,[2][3] though doing so can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. Noms français : 1-(3-CHLORO-2-PROPENYL)-3,5,7-TRIAZA-1-AZONIATRICYCLO(3.3.1.1(3,7))DECANE CHLORIDE 1-(3-CHLOROALLYL)-3,5,7-TRIAZA-1-AZONIAADAMANTANE CHLORIDE 3,5,7-TRIAZA-1-AZONIAADAMANTANE, 1-(3-CHLOROALLYL)-, CHLORIDE 3,5,7-TRIAZA-1-AZONIATRICYCLO(3.3.1.1(3,7)DECANE, 1-(3-CHLORO-2-PROPENYL)-, CHLORIDE 3,5,7-TRIAZA-1-AZONIATRICYCLO(3.3.1.13,7)DECANE, 1-(3-CHLORO-2-PROPENYL)-, CHLORIDE 3-Chloroallylochlorure de méthenamine CCTA Chlorure de 1-(3-chloroallyl)-3,5,7-triaza-1-azonia-adamantane Chlorure de N-(chloro-3 allyl) hexaminium Chlorure de N-(chloro-3 allyl) hexaminium (Quaternium 15) N-(3-CHLOROALLYL)HEXAMINIUM CHLORIDE N-(CHLORO-3 ALLYL) HEXAMINIUM, CHLORURE DE Noms anglais :Methenamine 3-chloroallylochloride; Utilisation et sources d'émission : Bactéricide, fabrication de cosmétiques. 1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride 3,5,7-Triaza-1-azoniaadamantane, 1-(3-chloroallyl)-, chloride 3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propen-1-yl)-, chloride (1:1) 3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propenyl)-, chloride Cinartc 200 Dowco 184 Dowicide Q Dowicil 100 Dowicil 75 Hexamethylenetetramine chloroallyl chloride Methenamine 3-chloroallylochloride N-(3-Chloroallyl)hexaminium chloride Quaternium-15 XD-1840 Translated names 1-(3-chlorallyl)-3,5,7-triaza-1-azoniaadamantan-chlorid (CTAC) (cs) 3-chloroallylochlorure de méthénamine (CTAC) (fr) 3-Cloroalilcloreto de metenamina (CTAC) (pt) 3-Cloroalilocloruro de metenamina (CTAC) (es) 3-cloroallilocloruro di metenamina (CTAC) (it) 3-Kloroalliloklorur tal-metenammina (CTAC) (mt) 3-χλωραλλυλοχλωρίδιο της μεθεναμίνης (CTAC) (el) Chlorek 3-chloroallilometenaminy (CTAC) (pl) Meteenamiin-3-kloroallülokloriid (CTAC) (et) Metenamiini-3-klooriallyylokloridi (CTAC) (fi) Metenamin 3-cloroaliloclorură (CTAC) (ro) Metenamin 3-kloroaliloklorid (CTAC) (hr) Metenamin-3-kloroallylklorid (CTAC) (sv) Metenamino 3-chloralilochloridas (CTAC) (lt) Methenamin-3-chlorallylchlorid (CTAC) (de) methenamin-3-chlorallylochlorid (CTAC) (da) Methenamine 3-chloroallylochloride (CTAC) (no) Methenamine-3-chloorallylchloride (CTAC) (nl) Metén-amin-3-klór-allil-klorid (CTAC) (hu) meténamín-3-chlóralylchlorid (CTAC) (sk) Metēnamīna 3-hloralilhlorīds (CTAC) (lv) Метенаминов 3-хлороалилохлорид (CTAC) (bg) 1-(3-chloroprop-2-en-1-yl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.1~3,7~]decane chloride 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane,1-(3-chloro-2-propenyl)-, chloride 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane,1-(3-chloro-2-propenyl)-, chloride (9CI) 3,5,7-TRIAZA-1-AZONIATRICYCLODECANE-1-(3-CHLORO-2-PROPENYL)-,CHLORIDE CHLOROALLYLTRIAZAAZONIAADAMANTANE CHLORIDE. 1-(3-Chloro-2-propenyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane Chloride 1-[(2E)-3-Chlor-2-propen-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decanchlorid [German] [ACD/IUPAC Name] 1-[(2E)-3-Chloro-2-propen-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane chloride [ACD/IUPAC Name] 1-[(2E)-3-Chloroprop-2-en-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane chloride 1-[(2E)-3-chloroprop-2-en-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane chloride 2W5B4VJ152 3,5,7-Triaza-1-azoniaadamantane, 1- (3-chloroallyl)-, chloride 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-[(2E)-3-chloro-2-propen-1-yl]-, chloride (1:1) [ACD/Index Name] 3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-[(2E)-3-chloro-2-propenyl]-, chloride 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-(3-chloro-2-propenyl)-, chloride 4080-31-3 [RN] Chlorure de 1-[(2E)-3-chloro-2-propén-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]décane [French] [ACD/IUPAC Name] Quaternium-15 [Wiki] QUATERNIUM-15 TRANS-FORM 1-(3-Chloroallyl)-1,3,5,7-tetraazaadamantan-1-ium chloride 1-(3-CHLOROALLYL)-3,5,7-TRIAZA-1-AZONIAADAMANTANECHLORIDE 1-(3-Chloroallyl)-3,5,7-triazo-1-azoniaadamantane chloride 3,5,7-Triaza-1-azoniaadamantane, 1-(3-chloroallyl)-, chloride 3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propenyl)-, chloride 51229-78-8 [RN] Chloroallyl methenamine chloride Cinartc 200 DOWICIDE Q Dowicil 100 Dowicil 100[1-(3-chloroallyl)-3,5,7-triazo-1-azoniaadamantane chloride] Dowicil 200 Dowicil 75 Dowicil75 EINECS 223-805-0 Hexamethylenetetramine chloroallyl chloride Methenamine 3-chloroallylochloride N-(3-CHLORALLYL)HEXAMINIUM CHLORIDE N-(3-Chloroallyl)hexaminium chloride quaternium 15

QUATERNIUM-16, N° CAS : 64425-88-3 / 35239-12-4, Origine(s) : Synthétique, Nom INCI : QUATERNIUM-16, N° EINECS/ELINCS : 264-890-4 / -. Classification : Ammonium quaternaire: Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Quaternary ammonium compounds, tris(hydroxyethyl)tallow alkyl, chlorides; 1-Octadecanaminium, N,N,N-tris(2-hydroxyethyl)-, chloride (1:1) [ACD/Index Name] 35239-12-4 [RN] Chlorure de N,N,N-tris(2-hydroxyéthyl)-1-octadécanaminium [French] [ACD/IUPAC Name] N,N,N-Tris(2-hydroxyethyl)-1-octadecanaminium chloride [ACD/IUPAC Name] N,N,N-Tris(2-hydroxyethyl)-1-octadecanaminiumchlorid [German] [ACD/IUPAC Name] QUATERNIUM-16 TRIS(2-HYDROXYETHYL)(OCTADECYL)AZANIUM CHLORIDE

QUATERNIUM-18, N° CAS : 61789-80-8, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-18, N° EINECS/ELINCS : 263-090-2. Classification : Ammonium quaternaire, Libérateur de Formaldéhyde. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Noms français : DIHYDROGENATEDTALLOW DIMETHYL AMMONIUM CHLORIDE; N,N-DIHYDROGENATEDTALLOW N,N-DIMETHYL AMMONIUM CHLORIDE Noms anglais : BIS(HYDROGENATED TALLOW)DIMETHYLAMMONIUM CHLORIDE; QUATERNARY AMMONIUM COMPOUNDS, BIS(HYDROGENATED TALLOW ALKYL)DIMETHYL, CHLORIDES. Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides; bis(hydrogenated tallow alkil)dimethyl, chlorides; Bis(hydrogenated tallow alkyl)dimethylammonium chlorides; Distearyldimethylammonium chloride; N,N-Dimethyl-N,N-di-n-alkyl(C16-18)-ammoniumchloride; Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl chlorides. 107-64-2 [RN] 1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, chloride (1:1) [ACD/Index Name] 203-508-2 [EINECS] Aliquat 207 Ammonium, dimethyldioctadecyl-, chloride BQ1923000 Chlorure de N,N-diméthyl-N-octadécyl-1-octadécanaminium [French] [ACD/IUPAC Name] Dimethyl dioctadecyl ammonium chloride DIMETHYL DIOCTADECYLAMMONIUM CHLORIDE Dimethyldioctadecylammonium chloride [Wiki] Dimethyldistearylammonium Chloride Di-n-octadecyldimethylammonium chloride dioctadecyl dimethyl ammonium chloride dioctadecyldimethylammonium chloride Distearyl dimethylammonium chloride DISTEARYLDIMETHYLAMMONIUM CHLORIDE Distearyldimonium chloride DODAC MFCD00055540 [MDL number] N,N-Dimethyl-N-octadecyl-1-octadecanaminium chloride [ACD/IUPAC Name] N,N-Dimethyl-N-octadecyl-1-octadecanaminiumchlorid [German] [ACD/IUPAC Name] N,N-Dimethyl-N-octadecyloctadecan-1-aminium chloride OM9573ZX3X [107-64-2] 12677-13-3 [RN] 129119-79-5 [RN] 134191-39-2 [RN] 14357-21-2 [RN] 1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, chloride 263-090-2 [EINECS] 59111-82-9 [RN] 61789-80-8 [RN] 66359-86-2 [RN] 76723-98-3 [RN] Adogen TA 100 Ammonyx 2200P100 Arosurf TA 100 Arosurf TA-100 Arquad 218-100 Arquad 218-100P Arquad R 40 Cation DS Cedequat TD 75 Dehyquart DAM Dimethyl distearylammonium chloride dimethyl(dioctadecyl)azanium and chloride Dimethyldi-n-octadecylammonium chloride dimethyldioctadecylamine, chloride dimethyl-dioctadecylammonium chloride dimethyl-dioctadecyl-ammonium chloride dimethyldioctadecylammoniumchloride dimethyl-dioctadecylazanium chloride dimethyl-dioctadecyl-azanium chloride DIMETHYLDIOCTADECYLAZANIUM CHLORIDE dimethyl-distearyl-ammonium chloride Dioctadecyldimethylammoniumchloride Distearyl dimethyl ammonium chloride DODA(Cl) EINECS 203-508-2 Genamin DSAC Jsp000681 Kemamine Q 9702CLP N,N-dimethyl-dioctadecyl ammonium chloride N,N-Dimethyl-N-octadecyl-1-octadecanaminiumchloride N,N-Dioctadecyl-N,N-dimethylammonium chloride Q-D 86P Quartamin D 86 Quartamin DM 86P Quaternium 5 QUATERNIUM-18 Quaternium-5 Sokalan 9200 Surfroyal DSAC Talofloc Varisoft 100 Varisoft TA 100

QUATERNIUM-22, N° CAS : 51812-80-7 / 82970-95-4. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-22. Nom chimique : 3-(D-Gluconoylamino)propyl(2-hydroxyethyl)dimethylammonium chloride. N° EINECS/ELINCS : 257-440-3. Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface, Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. -(D-gluconoylamino)propyl(2-hydroxyethyl)dimethylammonium chloride; (2-hydroxyethyl)dimethyl{3-[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanamido]propyl}azanium chloride; 1-Propanaminium, 3-(D-gluconoylamino)-N-(2-hydroxyethyl)-N,N-dimethyl-, chloride; CERAPHYL® 60 (ca. 60% substance in water). Jump to main contentJump to site nav Home About us Web APIs Help Sign in ChemSpider Search and share chemistry Search ChemSpider For medical information relating to Covid-19, please consult the World Health Organisation or local healthcare provision. Simple Structure Advanced History Found 1 result Search term: 51812-80-7 (Found by approved synonym) COMMENT ON THIS RECORD ChemSpider 2D Image | QUATERNIUM-22 | C13H29ClN2O7Save3DZoom QUATERNIUM-22 Molecular FormulaC13H29ClN2O7 Average mass360.832 Da Monoisotopic mass360.166321 Da ChemSpider ID36681 defined stereocentres - 4 of 4 defined stereocentres More details: This record has not been tagged. TAG Names Properties Searches Spectra Vendors Articles More Names and SynonymsDatabase ID(s) Validated by Experts, Validated by Users, Non-Validated, Removed by Users 257-440-3 [EINECS] 51812-80-7 [RN] Chlorure de N-(2-hydroxyéthyl)-N,N-diméthyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminium [French] [ACD/IUPAC Name] Chlorure de N-(2-hydroxyéthyl)-N,N-diméthyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminium (non-preferred name) [French] [ACD/IUPAC Name] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminium chloride [ACD/IUPAC Name] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminium chloride (non-preferred name) [ACD/IUPAC Name] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminiumchlorid [German] [ACD/IUPAC Name] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminiumchlorid (non-preferred name) [German] [ACD/IUPAC Name] QUATERNIUM-22 (2-HYDROXYETHYL)DIMETHYL{3-[(2R,3S,4R,5R)-2,3,4,5,6-PENTAHYDROXYHEXANAMIDO]PROPYL}AZANIUM CHLORIDE (α-Gluconamidopropyl)dimethyl-2-hydroxyethylammonium chloride [51812-80-7] 149358-34-9 [RN] 1-Propanaminium, 3-(D-gluconoylamino)-N-(2-hydroxyethyl)-N,N-dimethyl-, chloride 3-(D-Gluconoylamino)-N-(2-hydroxyethyl)-N,N-dimethyl-1-propanamin- ium chloride 3-(D-Gluconoylamino)propyl(2-hydroxyethyl)dimethylammonium chloride 82970-95-4 [RN] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminiumchloride QUATERNIUM 22 γ-Gluconamidopropyl dimethyl 2-hydroxyethyl ammonium chloride

Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Octyl decyl dimethyl ammonium chloride; QUATERNIUM-24, N° CAS : 32426-11-2, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-24. Nom chimique : Decyldimethyloctylammonium chloride. N° EINECS/ELINCS : 251-035-5, Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes, Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface, Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Noms français : 1-DECANAMINIUM, N,N-DIMETHYL-N-OCTYL-, CHLORIDE; Chlorure de décyldiméthyloctylammonium; DECYLOCYTLDIMETHYLAMMONIUM CHLORIDE. OCTYL DECYL DIMETHYL AMMONIUM CHLORIDE. Noms anglais : 1-Decaminium N-octyl-N,N-dimethyl-, chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Octyl decyl dimethyl ammonium chloride; 1-Decanaminium, N,N-dimethyl-N-octyl-, chloride (1:1) [ACD/Index Name] ; 251-035-5 [EINECS] ; 32426-11-2 [RN]; Chlorure de N,N-diméthyl-N-octyl-1-décanaminium [French] [ACD/IUPAC Name]; Decyloctyldimethylammonium chloride; N,N-Dimethyl-N-octyl-1-decanaminium chloride [ACD/IUPAC Name]; N,N-Dimethyl-N-octyl-1-decanaminiumchlorid [German] [ACD/IUPAC Name]; N,N-Dimethyl-N-octyldecan-1-aminium chloride; Quaternium-24 ; 1-Decaminium, N-octyl-N,N-dimethyl-, chloride; 1-Decanaminium, N,N-dimethyl-N-octyl-, chloride; Ammonium, decyldimethyloctyl, chloride; Decyl dimethyl octyl ammonium chloride; decyl-dimethyl-octylammonium chloride; decyl-dimethyl-octyl-ammonium chloride; DECYLDIMETHYLOCTYLAMMONIUM CHLORIDE; decyl-dimethyl-octylazanium and chloride; decyl-dimethyl-octylazanium chloride; decyl-dimethyl-octyl-azanium chloride; DECYLDIMETHYLOCTYLAZANIUM CHLORIDE; decyl-dimethyl-octylazanium;chloride; Decylocytldimethylammonium chloride ; Di-(Octyl-decyl)dimethylammonium chloride; EINECS 251-035-5; N,N-Dimethyl-N-octyl-1-decanaminiumchloride; N-Octyl-N-decyl-N-dimethylammonium chloride; N-Octyl-N-decyl-N-dimethyl-ammonium chloride; Octyl Decyldimethyl Ammonium Chloride; Quaternium 24

QUATERNIUM-26, N° CAS : 68953-64-0 / 64156-20-3, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-26, N° EINECS/ELINCS : 273-222-0. Classification : Ammonium quaternaire Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. 1-Propanaminium, 3-amino-N-(2-hydroxyethyl)-N,N-dimethyl-, N-mink-oil acyl derivs., chlorides; EC Inventory, ; 1-Propanaminium, 3-amino-N-(2-hydroxyethyl)-N,N-dimethyl-, N-mink-oil acyl derivs, chlorides; CERAPHYL 65 ; Quaternium-26

QUATERNIUM-27, N° CAS : 68122-86-1. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-27. N° EINECS/ELINCS : 268-531-2. Classification : Ammonium quaternaire. Ses fonctions (INCI), Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Noms français : Méthylsulfate de composés imidazolium du dihydro-4,5 méthyl-1 alkyle de suif nor-2 (amidoéthyl-2 de suif)-1 Noms anglais : 1-(2-TALLOW AMIDOETHYL)-1-METHYL-2-NOR(TALLOW ALKYL)-2-IMIDAZOLINIUM METHYL SULFATE 1-(2-TALLOWAMIDOETHYL)-1-METHYL-2-TALLOWALKYLIMIDAZOLINIUM METHYLSULFATE 1-METHYL-1-(2-TALLOWAMIDOETHYL)-2-TALLOWIMIDAZOLINIUM METHYLSULFATE 1-METHYL-1-TALLOWALKYLAMIDOETHYL-2-TALLOWALKYLIMIDAZOLINE METHOSULFATE IMIDAZOLIUM COMPOUNDS, 4,5-DIHYDRO-1-METHYL-2-NORTALLOW ALKYL-1-(2-TALLOW AMIDOETHYL), ME SULFATES; Imidazolium compounds, 4,5-dihydro-1-methyl-2-nortallow alkyl-1-(2-tallow amidoethyl), Me sulfates.

QUATERNIUM-33, N° CAS : 72102-40-0 / 86221-07-0, Origine(s) : Synthétique, Nom INCI : QUATERNIUM-33, N° EINECS/ELINCS : 276-339-5. Classification : Ammonium quaternaire: Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. 1-Propanaminium, 3-amino-N-ethyl-N,N-dimethyl-, N-lanolin acyl derivs., Et sulfates; Lanolin acids, APMA amide, di-Et sulfate; Quaternium-33; iso and antiso C10-40 AAP EDM-ES

QUATERNIUM-45; N° CAS : 21034-17-3; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-45; Nom chimique : 3,4-Dimethyl-2-[2-(phenylamino)vinyl]oxazolium iodide; N° EINECS/ELINCS : 244-158-0; Classification : Ammonium quaternaire. Ses fonctions (INCI). 3,4-dimethyl-2-[2-(phenylamino)vinyl]oxazolium iodide. : 3,4-dimethyl-2-[(E)-2-(phenylamino)ethenyl]-1,3-oxazol-3-ium iodide. Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. 2-[(E)-2-Anilinovinyl]-3,4-dimethyl-1,3-oxazol-3-ium iodide [ACD/IUPAC Name] ; 2-[(E)-2-Anilinovinyl]-3,4-dimethyl-1,3-oxazol-3-iumiodid [German] [ACD/IUPAC Name]; 244-158-0 [EINECS]; Iodure de 2-[(E)-2-anilinovinyl]-3,4-diméthyl-1,3-oxazol-3-ium [French] [ACD/IUPAC Name]; Oxazolium, 3,4-dimethyl-2-[(E)-2-(phenylamino)ethenyl]-, iodide (1:1) [ACD/Index Name]; 21034-17-3 [RN]; 3,4-Dimethyl-2-(2-(phenylamino)vinyl)oxazolium iodide; 3,4-DIMETHYL-2-[2-(PHENYLAMINO)ETHENYL]-1,3-OXAZOL-3-IUM IODIDE; 3,4-dimethyl-2-[2-(phenylamino)vinyl]oxazolium iodide; Kankohso 401; Kankohso 401 [Japanese]; Oxazolium, 2-(2-anilinovinyl)-3,4-dimethyl-, iodide; Oxazolium, 3,4-dimethyl-2-(2-(phenylamino)ethenyl)-, iodide (9CI); Quaternium-45

QUATERNIUM-51; N° CAS : 1463-95-2; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-51; N° EINECS/ELINCS : 215-976-5. Classification : Ammonium quaternaire; 2-[2-[(5-bromo-2-pyridyl)amino]vinyl]-1-ethyl-6-methylpyridinium iodide; : 2-[(E)-2-[(5-bromopyridin-2-yl)amino]ethenyl]-1-ethyl-6-methylpyridin-1-ium iodide. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. 2-{(E)-2-[(5-Brom-2-pyridinyl)amino]vinyl}-1-ethyl-6-methylpyridiniumiodid [German] [ACD/IUPAC Name]; 2-{(E)-2-[(5-Bromo-2-pyridinyl)amino]vinyl}-1-ethyl-6-methylpyridinium iodide [ACD/IUPAC Name]; 2-{(E)-2-[(5-Bromopyridin-2-yl)amino]vinyl}-1-ethyl-6-methylpyridinium iodide ;215-976-5 [EINECS]; Iodure de 2-{(E)-2-[(5-bromo-2-pyridinyl)amino]vinyl}-1-éthyl-6-méthylpyridinium [French] [ACD/IUPAC Name]; Pyridinium, 2-[(E)-2-[(5-bromo-2-pyridinyl)amino]ethenyl]-1-ethyl-6-methyl-, iodide (1:1) [ACD/Index Name]; 1463-95-2 [RN]; 2-(2-((5-Bromo-2-pyridyl)amino)vinyl)-1-ethyl-6-methylpyridinium iodide; 2-[(E)-2-[(5-BROMOPYRIDIN-2-YL)AMINO]ETHENYL]-1-ETHYL-6-METHYLPYRIDIN-1-IUM IODIDE; 2-[2-[(5-bromo-2-pyridyl)amino]vinyl]-1-ethyl-6-methylpyridinium iodide; Pyridinium, 2-(2-((5-bromo-2-pyridinyl)amino)ethenyl)-1-ethyl-6-methyl-, iodide ;Pyridinium,2-[2-[(5-bromo-2-pyridinyl)amino]ethenyl]-1-ethyl-6-methyl-, iodide (1:1); Quaternium-51

QUATERNIUM-52, N° CAS : 58069-11-7. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-52. Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface, Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance, Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Poly(oxy-1,2-ethanediyl), α,α',α''-[(octadecylnitrilio)tri-2,1-ethanediyl]tris[ω-hydroxy-, phosphate (1:1); Talgaminphosphat, ethoxyliert

QUATERNIUM-53; N° CAS : 68410-69-5; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-53; N° EINECS/ELINCS : 268-762-9; Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Noms français : Méthylsulfate de dérivés méthylés de suif et de diéthylènetriamine,polyéthoxylés. Noms anglais :METHYL TALLOW DIETHYLENETRIAMINE CONDENSATE, POLYETHOXYLATED, METHYL SULFATE; Poly(oxy-1,2-ethanediyl),alpha-(2-(bis(2-aminoethyl)methylammonio- )ethyl)-omega-hydroxy, N,N'-ditallow acyl derivs, methyl sulfates; ; Noms français : Méthylsulfate de dérivés méthylés de suif et de diéthylènetriamine,polyéthoxylés. Noms anglais : METHYL TALLOW DIETHYLENETRIAMINE CONDENSATE, POLYETHOXYLATED, METHYL SULFATE; Poly(oxy-1,2-ethanediyl),alpha-(2-(bis(2-aminoethyl)methylammonio- )ethyl)-omega-hydroxy, N,N'-ditallow acyl derivs, methyl sulfates

QUATERNIUM-60 Origine(s) : Synthétique Nom INCI : QUATERNIUM-60 Classification : Ammonium quaternaire Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-70; N° CAS : 68921-83-5; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-70; Nom chimique : Dimethyl[3-[(1-oxooctadecyl)amino]propyl][2-oxo-2-(tetradecyloxy)ethyl]ammonium chloride; N° EINECS/ELINCS : 272-964-2; Classification : Ammonium quaternaire; Ses fonctions (INCI): Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface ; Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Dimethyl[3-[(1-oxooctadecyl)amino]propyl][2-oxo-2-(tetradecyloxy)ethyl]ammonium chloride; Ceraphyl 70 ; dimethyl(3-octadecanamidopropyl)[2-oxo-2-(tetradecyloxy)ethyl]azanium chloride; 1-Propanaminium, N,N-dimethyl-3-[(1-oxooctadecyl)amino]-; N-[2-oxo-2-(tetradecyloxy)ethyl]-, chloride (1:1) [ACD/Index Name]; 272-964-2 [EINECS]; 68921-83-5 [RN]; Chlorure de N,N-diméthyl-N-[2-oxo-2-(tétradécyloxy)éthyl]-3-(stearoylamino)-1-propanaminium [French] [ACD/IUPAC Name]; N,N-Dimethyl-N-[2-oxo-2-(tetradecyloxy)ethyl]-3-(stearoylamino)-1-propanaminium chloride [ACD/IUPAC Name]; N,N-Dimethyl-N-[2-oxo-2-(tetradecyloxy)ethyl]-3-(stearoylamino)-1-propanaminiumchlorid [German] [ACD/IUPAC Name]; N,N-Dimethyl-N-[2-oxo-2-(tetradecyloxy)ethyl]-3-(stearoylamino)propan-1-aminium chloride; Quaternium-70; (2-keto-2-myristyloxy-ethyl)-dimethyl-(3-stearamidopropyl)ammonium chloride; (3-Stearamidopropyl)dimethylmyristoyloxycarbonylmethylammonium chloride ; 1-Propanaminium, N,N-dimethyl-3-((1-oxooctadecyl)amino)-N-(2-oxo-2-(tetradecenylox- y)ethyl)-, chloride; 1-Propanaminium, N,N-dimethyl-3-((1-oxooctadecyl)amino)-N-(2-oxo-2-(tetradecyloxy)ethyl)-, chloride; Dimethyl(3-((1-oxooctadecyl)amino)propyl)(2-oxo-2-(tetradecyloxy)ethyl)ammonium chloride; DIMETHYL(3-OCTADECANAMIDOPROPYL)[2-OXO-2-(TETRADECYLOXY)ETHYL]AZANIUM CHLORIDE; dimethyl-[3-(1-oxooctadecylamino)propyl]-(2-oxo-2-tetradecoxyethyl)ammonium chloride; dimethyl-[3-(octadecanoylamino)propyl]-(2-oxo-2-; tetradecoxy-ethyl)ammonium chloride; dimethyl-[3-(octadecanoylamino)propyl]-(2-oxo-2-tetradecoxyethyl)azanium chloride; dimethyl-[3-(octadecanoylamino)propyl]-(2-oxo-2-tetradecoxy-ethyl)azanium chloride; dimethyl[3-[(1-oxooctadecyl)amino]propyl][2-oxo-2-(tetradecyloxy)ethyl]ammonium chloride, EINECS 272-964-2; N,N-Dimethyl-3-((1-oxooctadecyl)amino)-N-(2-oxo-2-(tetradecenylox- y)ethyl)-1-propanaminium chloride; Stearamidopropyl dimethyl (myristyl acetate) ammonium chloride

QUATERNIUM-73; N° CAS : 15763-48-1; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-73; Nom chimique : 3-Heptyl-2-[(3-heptyl-4-methyl-3H-thiazol-2-ylidene)methyl]-4-methylthiazolium iodide; 3-heptyl-2-[(3-heptyl-4-methyl-3H-thiazol-2-ylidene)methyl]-4-methylthiazolium iodide; 3-heptyl-2-{[(2Z)-3-heptyl-4-methyl-2,3-dihydro-1,3-thiazol-2-ylidene]methyl}-4-methyl-1,3-thiazol-3-ium iodide; N° EINECS/ELINCS : 239-852-5. Classification : Ammonium quaternaire; Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surfa. 239-852-5 [EINECS] 3-Heptyl-2-[(3-heptyl-4-methyl-1,3-thiazol-2(3H)-ylidene)methyl]-4-methyl-1,3-thiazol-3-ium iodide 3-Heptyl-2-[(E)-(3-heptyl-4-methyl-1,3-thiazol-2(3H)-yliden)methyl]-4-methyl-1,3-thiazol-3-iumiodid [German] [ACD/IUPAC Name] 3-Heptyl-2-[(E)-(3-heptyl-4-methyl-1,3-thiazol-2(3H)-ylidene)methyl]-4-methyl-1,3-thiazol-3-ium iodide [ACD/IUPAC Name] Iodure de 3-heptyl-2-[(E)-(3-heptyl-4-méthyl-1,3-thiazol-2(3H)-ylidène)méthyl]-4-méthyl-1,3-thiazol-3-ium [French] [ACD/IUPAC Name] thiazolium, 3-heptyl-2-[(3-heptyl-4-methyl-2(3H)-thiazolylidene)methyl]-4-methyl-, iodide (1:1) Thiazolium, 3-heptyl-2-[(E)-(3-heptyl-4-methyl-2(3H)-thiazolylidene)methyl]-4-methyl-, iodide (1:1) [ACD/Index Name] 15763-48-1 [RN] 3-Heptyl-2-((3-heptyl-4-methyl-3H-thiazol-2-ylidene)methyl)-4-methylthiazolium iodide 3-Heptyl-2-((3-heptyl-4-methyl-4-thiazolin-2-ylidene)methyl)-4-methylthiazolium iodide 3-HEPTYL-2-[(3-HEPTYL-4-METHYL-1,3-THIAZOL-2-YLIDENE)METHYL]-4-METHYL-1,3-THIAZOL-3-IUM IODIDE 3-heptyl-2-[(3-heptyl-4-methyl-3H-thiazol-2-ylidene)methyl]-4-methylthiazolium iodide 3-HEPTYL-2-{[(2E)-3-HEPTYL-4-METHYL-1,3-THIAZOL-2-YLIDENE]METHYL}-4-METHYL-1,3-THIAZOL-3-IUM IODIDE Kankohso 201 MFCD01680792 Pionin Quaternium 73 QUATERNIUM-73 Thiazolium, 3-heptyl-2-((3-heptyl-4-methyl-2(3H)-thiazolylidene)methyl)-4-methyl-, iodide Thiazolium, 3-heptyl-2-((3-heptyl-4-methyl-4-thiazolin-2-ylidene)methyl)-4-methyl-, iodide

QUATERNIUM-75 Origine(s) : Synthétique Nom INCI : QUATERNIUM-75 Classification : Ammonium quaternaire Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-8; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-8. Classification : Ammonium quaternaire. Ses fonctions (INCI); Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes. Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance; It helps make drying easier, whilst it totally respects hair structure. It protects the hair from the heat damage caused by hairdryer or hair iron, as well from mechanical stress. It has softening, conditioning and antistatic proprieties.

QUATERNIUM-80, N° CAS : 134737-05-6. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-80. Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface : Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Quaternium-80 is the quaternary ammonium salt with the alkyl groups derived from coconut oil; Siloxanes and Silicones, di-Me, 3-[3-[(3-coco amidopropyl)dimethylammonio]-2-hydroxypropoxy]propyl group-terminated, acetates (salts); Siloxanes and silicones, di-Me, 3-{3-[(3-Cocoamidopropyl) -dimethylammonia]-2-hydroxy-propoxy}propyl group terminated, acetates (salts)

QUATERNIUM-82, N° CAS : 65059-61-2 / 173833-36-8. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-82. N° EINECS/ELINCS : 265-339-0 / -. Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. [2-[bis(2-hydroxypropyl)amino]ethyl]bis(2-hydroxypropyl)(methyl)ammonium methyl sulphate, dioleate (ester); (2-hydroxypropyl)({2-[(2-hydroxypropyl)({2-[(9E)-octadec-9-enoyloxy]propyl})amino]ethyl})methyl({2-[(10E)-octadec-10-enoyloxy]propyl})azanium methyl sulfate; 2-Hydroxy-N-{2-[(2-hydroxypropyl){2-[(9E)-9-octadecenoyloxy]propyl}amino]ethyl}-N-methyl-N-{2-[(10E)-10-octadecenoyloxy]propyl}-1-propanaminium methyl sulfate [ACD/IUPAC Name] 2-Hydroxy-N-{2-[(2-hydroxypropyl){2-[(9E)-9-octadecenoyloxy]propyl}amino]ethyl}-N-methyl-N-{2-[(10E)-10-octadecenoyloxy]propyl}-1-propanaminiummethylsulfat [German] [ACD/IUPAC Name] Sulfate de 2-hydroxy-N-{2-[(2-hydroxypropyl){2-[(9E)-9-octadecenoyloxy]propyl}amino]éthyl}-N-méthyl-N-{2-[(10E)-10-octadecenoyloxy]propyl}propane et de méthyle [French] [ACD/IUPAC Name] (2-(Bis(2-hydroxypropyl)amino)ethyl)bis(2-hydroxypropyl)(methyl)ammonium methyl sulphate, dioleate (ester) (2-HYDROXYPROPYL)({2-[(2-HYDROXYPROPYL)({2-[(9E)-OCTADEC-9-ENOYLOXY]PROPYL})AMINO]ETHYL})METHYL({2-[(10E)-OCTADEC-10-ENOYLOXY]PROPYL})AZANIUM METHYL SULFATE(1-) 1-Propanaminium, N-(2-(bis(2-hydroxypropyl)amino)ethyl)-2-hydroxy-N-(2-hydroxypropyl)-N-methyl-, di-(9Z)-9-octadecenoate (ester), methyl sulfate (salt) 265-339-0 [EINECS] 65059-61-2 [RN]

QUATERNIUM-83, N° CAS : 91723-55-6. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-83. N° EINECS/ELINCS : 294-563-1. Classification : Ammonium quaternaire. Ses fonctions (INCI): Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-87, N° CAS : 92201-88-2. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-87. N° EINECS/ELINCS : 931-745-8. Classification : Ammonium quaternaire. Ses fonctions (INCI): Agent nettoyant : Aide à garder une surface propre. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

QUATERNIUM-88, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-88. Classification : Ammonium quaternaire. Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-89 Origine(s) : Synthétique Nom INCI : QUATERNIUM-89 Classification : Ammonium quaternaire Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-90, Origine(s) : Synthétique, Nom INCI : QUATERNIUM-90. Classification : Ammonium quaternaire. Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface

QUATERNIUM-91 Origine(s) : Synthétique Nom INCI : QUATERNIUM-91 Classification : Ammonium quaternaire Ses fonctions (INCI) Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-95; N° CAS : 1030827-59-8; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-95. Classification : Ammonium quaternaire. Ses fonctions (INCI). Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV

QUATERNIUM-96, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-96. Classification : Ammonium quaternaire. Ses fonctions (INCI). Agent nettoyant : Aide à garder une surface propre. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

SYNONYMS C.I.Acid Yellow 3; C.I. 47005; Quinoline Yellow, water soluble; Food Yellow 13; Sodium 2-(1,3-dioxoindan-2-yl)quinolinedisulfonate; 2-(1,3-Dioxoindan-2-yl) quinolinedisulfonic acid sodium salt; Sodium 2-(2-quinolyl) indan-1,3-dione-disulfonates; Quinoline Yellow;CAS NO 8004-92-0

quercus infectoria fruit extract;oak fruit extract CAS NO:93165-57-2

ood Yellow 13; Sodium 2-(1,3-dioxoindan-2-yl)quinolinedisulfonate; 2-(1,3-Dioxoindan-2-yl) quinolinedisulfonic acid sodium salt; Sodium 2-(2-quinolyl) indan-1,3-dione-disulfonates CAS:8004-92-0

SYNONYMS C.I.Acid Yellow 3; C.I. 47005; Quinoline Yellow, water soluble; Food Yellow 13; Sodium 2-(1,3-dioxoindan-2-yl)quinolinedisulfonate; 2-(1,3-Dioxoindan-2-yl) quinolinedisulfonic acid sodium salt; Sodium 2-(2-quinolyl) indan-1,3-dione-disulfonates; Quinoline YellowCAS NO 8004-92-0

Quartemine; 1-Hexadecanaminium, N,N,N-trimethyl-, chloride cas no: 112-02-7

SYNONYMS Aciphex;2-[[[4-(3-methoxypropoxy) -3-methyl-2-pyridinyl]-methyl]sulfinyl] -1H–benzimidazole sodium salt; cas no:117976-89-3

Radia 7513 представляет собой сложный эфир, полученный в результате реакции тридецилового спирта в сочетании со стеариновой кислотой.


Номер CAS: 95912-88-2
Эйнекс: 306-084-8
Химическое название: изотридецил стеарат.
химическое название: жирные кислоты, C16-18, изотридециловые эфиры.


В виде сырья Radia 7513 описывается как прозрачная маслянистая жидкость, которая может иметь светло-желтый оттенок.
Группа экспертов по обзору косметических ингредиентов признала Radia 7513 безопасным.


Radia 7513 содержит в качестве спиртового компонента тридециловый спирт (1-тридеканол).
Стеараты представляют собой соли или эфиры стеариновой кислоты (октадекановой кислоты).
Radia 7513 представляет собой сложный эфир, полученный в результате реакции тридецилового спирта в сочетании со стеариновой кислотой.



ИСПОЛЬЗОВАНИЕ И ПРИМЕНЕНИЕ RADIA 7513:
Radia 7513 используется Ингредиенты для ухода за кожей.
Радиа 7513 или 11-метилдодецилоктадеканоат или октадекановая кислота представляет собой изотридециловый эфир.
Radia 7513 используется в продуктах по уходу за кожей, сырье для прядения и промасливании для текстиля, средствах для обработки резины, смазках для пластмасс, добавках к краскам и чернилам.


Radia 7513 — сложный эфир, используемый в качестве технологической добавки в полимерах.
Radia 7513 используется в качестве сырья для отделки прядения и промасливания для текстиля, средства для обработки резины, пластической смазки, добавки для красок и чернил.
Radia 7513 используется в косметике в качестве усилителя текстуры/загустителя и смягчающего средства и может быть как животного, так и синтетического происхождения (в компании Paula's Choice используется последнее).



РАДИА 7513 КРАТКИЙ ОБЗОР:
*Эфир, полученный в результате реакции тридецилового спирта в сочетании со стеариновой кислотой.
*Работает как усилитель текстуры/загуститель и смягчающее кожу смягчающее средство.
*Известен за быстрое впитывание и бархатистое послевкусие.
*Описывается как прозрачная маслянистая жидкость в виде сырья.



ФУНКЦИИ РАДИА 7513 В КОСМЕТИЧЕСКОЙ ПРОДУКЦИИ:
*КОНДИЦИОНИРОВАНИЕ КОЖИ
Radia 7513 поддерживает кожу в хорошем состоянии.



ФИЗИЧЕСКИЕ И ХИМИЧЕСКИЕ СВОЙСТВА РАДИА 7513:
Внешний вид: светло-желтая маслянистая жидкость.
кислотное число: макс. 1 мг КОН/г
прочее: йодное число: макс. 1 гI2/100 г.
вязкость при 40°С: 14-18 мм²/с
Влажность: макс 0,1%
Плотность: 0,85:
Температура вспышки: >210 °C.
Молекулярный вес: 466,8 г/моль
XLogP3-AA: 14,4
Количество доноров водородной связи: 0
Количество акцепторов водородной связи: 2
Количество вращающихся облигаций: 28
Точная масса: 466,47498122 г/моль.
Моноизотопная масса: 466,47498122 г/моль.
Топологическая площадь полярной поверхности: 26,3 Å ²
Количество тяжелых атомов: 33

Официальное обвинение: 0
Сложность: 377
Количество атомов изотопа: 0
Определенное количество стереоцентров атома: 0
Неопределенное количество стереоцентров атома: 0
Определенное количество стереоцентров связи: 0
Неопределенное количество стереоцентров связи: 0
Количество единиц ковалентной связи: 1
Соединение канонизировано: Да
LogP: 14,386 (оценка)
Оценка еды по версии EWG: 1
Внешний вид: Прозрачная жидкость от бесцветного до светло-желтого цвета.
Чистота: минимум 96%.
Температура кипения: 490С.
Температура вспышки: 255С.
Относительная плотность: около 0,9
Кислотное число: максимум 1,0.
Степень омыления: 120 – 130
Гидроксильное число: максимум 3.
Цвет: максимум 50 афа.
Влажность: максимум 0,1%.



МЕРЫ ПЕРВОЙ ПОМОЩИ RADIA 7513:
-Описание мер первой помощи:
*При вдыхании:
При вдыхании выведите пострадавшего на свежий воздух.
*При попадании на кожу:
Смыть большим количеством воды с мылом.
*В случае зрительного контакта:
В качестве меры предосторожности промойте глаза водой.
*При проглатывании:
Никогда не давайте ничего перорально человеку, находящемуся без сознания.
Прополоскать рот водой.
-Указание на необходимость немедленной медицинской помощи и специального лечения:
Данные недоступны



МЕРЫ ПРИ СЛУЧАЙНОМ ВЫБРОСЕ RADIA 7513:
-Экологические меры предосторожности:
Никаких особых мер по охране окружающей среды не требуется.
-Методы и материалы для локализации и очистки:
Хранить в подходящих закрытых контейнерах для утилизации.



МЕРЫ ПОЖАРОТУШЕНИЯ РАДИА 7513:
-Средства пожаротушения:
*Подходящие средства пожаротушения:
Используйте водяной спрей, спиртостойкую пену, сухие химикаты или углекислый газ.
-Дальнейшая информация:
Данные недоступны



КОНТРОЛЬ ВОЗДЕЙСТВИЯ/ПЕРСОНАЛЬНАЯ ЗАЩИТА RADIA 7513:
-Параметры управления:
--Ингредиенты с параметрами контроля на рабочем месте:
-Средства контроля воздействия:
--Средства индивидуальной защиты:
*Защита глаз/лица:
Используйте средства защиты глаз
*Защита кожи:
Работайте в перчатках.
Вымойте и высушите руки.
Полный контакт:
Материал: Нитриловый каучук.
Минимальная толщина слоя: 0,4 мм.
Время прорыва: 480 мин.
Всплеск контакта:
Материал: Нитриловый каучук.
Минимальная толщина слоя: 0,4 мм.
Время прорыва: 480 мин.
*Защита тела:
Непроницаемая одежда.
*Защита органов дыхания:
Защита органов дыхания не требуется.
-Контроль воздействия на окружающую среду:
Никаких особых мер по охране окружающей среды не требуется.



ОБРАЩЕНИЕ И ХРАНЕНИЕ RADIA 7513:
-Условия безопасного хранения, включая любые несовместимости:
*Условия хранения:
Хранить в прохладном месте.
Хранить контейнер плотно закрытым в сухом и хорошо проветриваемом месте.



СТАБИЛЬНОСТЬ И РЕАКЦИОННАЯ СПОСОБНОСТЬ RADIA 7513:
-Реактивность:
Данные недоступны
-Химическая стабильность:
Стабилен при рекомендуемых условиях хранения.
-Возможность опасных реакций:
Данные недоступны
-Условия, чтобы избежать:
Данные недоступны



СИНОНИМЫ:
Фетцурен, C16-18-, изотридециловый эфир
Жирные кислоты, C16-18, изотридециловые эфиры
Жирные кислоты, C16-18, изотридециловые эфиры
Изотридецил стеарат
31565-37-4
11-метилдодецилоктадеканоат
Октадекановая кислота, изотридециловый эфир
Октадекановая кислота, изотридециловый эфир
J8793TKA30
Стеариновая кислота, изотридециловый эфир
ЭИНЭКС 250-703-3
UNII-J8793TKA30
EXCEPARL ТД-С
СХЕМБЛ2699239
ИЗОТРИДЕЦИЛ СТЕАРАТ [INCI]
W-110802
Q27281337
Изотридецилстеарат
изотридецил стеарат
11-метилдодецилоктадеканоат
Стеариновая кислота, изотридециловый эфир
Октадекановая кислота, изотридециловый эфир

RADIACID 0907 имеет 100% растительное происхождение.
Благодаря разветвленной структуре RADIACID 0907 обладает характерным смягчающим эффектом.
RADIACID 0907 не оставляет жирного ощущения.


НОМЕР КАС: 2724-58-5

НОМЕР ЕС: 250-178-0

МОЛЕКУЛЯРНАЯ ФОРМУЛА: C18H36O2

МОЛЕКУЛЯРНАЯ МАССА: 284,5 г/моль

НАЗВАНИЕ ИЮПАК: 16-метилгептадекановая кислота


RADIACID 0907 имеет прочную липидную пленку.
Мягкое ощущение кожи и придает глянцевый вид коже

RADIACID 0907 используется в декоративной косметике, дезодорантах и средствах личной гигиены, где он обеспечивает пленкообразующую и распределяющую функции.
RADIACID 0907 является исключительно хорошим смягчающим средством с приятным ощущением и широко используется в продуктах по уходу за кожей и телом.

RADIACID 0907 используется в следующих продуктах:
-моющие и чистящие средства
-клеи и герметики
-топливо
-смазки и смазки
-покрывные изделия
-удобрения

RADIACID 0907 используется в биоцидах (например, дезинфицирующих средствах, средствах для борьбы с вредителями)
RADIACID 0907 также используется в регуляторах pH и продуктах для очистки воды.

RADIACID 0907 может использоваться в лабораторных химикатах, средствах защиты растений, умягчителях воды и химикатах для обработки воды.
RADIACID 0907 используется для приготовления смесей
RADIACID 0907 используется для производства химикатов.

RADIACID 0907 готовят из соевого масла и жира.
RADIACID 0907 представляет собой прозрачную маслянистую жидкость от белого до бледно-желтого цвета.

RADIACID 0907 является жидкостью при комнатной температуре.
RADIACID 0907 химически, карбоксильная группа, присоединенная к алкильной цепи, метилированная, разветвленная на различных атомах углерода, делает ее намного более стабильной по сравнению с другими жирными кислотами с линейной цепью, включая окислительный потенциал.

RADIACID 0907 представляет собой раствор желтого цвета с химической формулой C18H36O2.
RADIACID 0907 представляет собой насыщенный раствор углерода.
RADIACID 0907 естественным образом содержится в мясных продуктах и растительных маслах.

RADIACID 0907 можно использовать в качестве смазки, улучшающей растекание порошковой смеси.
RADIACID 0907 обладает отличной растекаемостью без маслянистости.

RADIACID 0907 представляет собой молекулу жирной кислоты с основной цепью из 18 атомов углерода.
RADIACID 0907 является изомером стеариновой кислоты, что означает, что они оба имеют химическую формулу C18H36O2, но отличаются расположением атомов.

RADIACID 0907 используется в продуктах личной гигиены.
RADIACID 0907 также используется в косметической промышленности.

RADIACID 0907 обладает смазывающими или адгезивными свойствами.
RADIACID 0907 также используется в бумажной продукции.

В то время как стеариновая кислота имеет линейную углеродную цепь с 18 атомами углерода, изостерическая кислота имеет углеродную цепь с 17 атомами и одну углеродную ветвь у 16-го атома углерода. Его химическая структура может быть представлена как (CH3)2CH(CH2)14CO2H.
RADIACID 0907 естественным образом содержится в мясных продуктах и растительных маслах.

RADIACID 0907 имеет широкий спектр промышленного применения.
RADIACID 0907 в основном используется в качестве добавки к клеям или смазкам как для красок, так и для средств личной гигиены.

RADIACID 0907 является важным сырьем для приготовления специальных поверхностно-активных веществ для потребительских товаров по уходу.
RADIACID 0907 (RADIACID 0907) используется в синтезе метилразветвленных поли(гидроксиалканоатов), биосурфактантов и наночастиц серебра.

RADIACID 0907 представляет собой слаборазветвленную жидкую жирную кислоту, полученную в результате реакции олеиновой кислоты с природным минеральным катализатором.
В этой реакции нет химических добавок, RADIACID 0907 на 100% основан на исходном масле или жире.

RADIACID 0907 используется в тех случаях, когда требуется жидкая жирная кислота с исключительной стабильностью: термическая стабильность в случае смазки, стабильность запаха для косметических составов и устойчивость к окислению для продуктов с требованиями длительного срока хранения.
Разветвленная структура RADIACID 0907 также повышает его диспергирующую способность.

RADIACID 0907 имеет высокоэффективные смазочные материалы с превосходной морозостойкостью.
RADIACID 0907 используется в жидкостях для прокатки металлов.

Будучи жирной кислотой, RADIACID 0907 также является амфифильной, то есть представляет собой молекулу с гидрофобным и гидрофильным концами.
Таким образом, RADIACID 0907 может благоприятно взаимодействовать как с полярными, так и с неполярными молекулами, что позволяет ему действовать как поверхностно-активное вещество.

RADIACID 0907 также растворим во многих маслах, что позволяет использовать его в качестве эмульгатора или диспергатора.
Благодаря этому набору свойств RADIACID 0907 является полезной добавкой для различных применений, в том числе:

-Клеи
-Покрытия и краски
-Отделочные агенты
-Смазки
-герметики
-Растворители
-ПАВ
- Регуляторы вязкости

RADIACID 0907 используется в качестве косметического эфира.
RADIACID 0907 используется в производстве мыла.

RADIACID 0907 представляет собой жирную кислоту с длинной цепью.
RADIACID 0907 функционально связан с гептадекановой кислотой.
RADIACID 0907 — это натуральный продукт, обнаруженный в Aristolochia grandiflora, Streptomyces и других организмах, данные о которых имеются.


ФИЗИЧЕСКИЕ СВОЙСТВА:

-Молекулярный вес: 284,5 г/моль

-XLogP3: 7.2

-Точная масса: 284,271530387 г/моль

-Моноизотопная масса: 284,271530387 г/моль

-Площадь топологической полярной поверхности: 37,3 Ų

-Физическое описание: бесцветная жидкость.

-Точка кипения: 400 ° С

-Точка плавления: 69,5 ° С

-Растворимость: 0,007116 мг/л

-ЛогП: 7,674

-Показатель преломления: 1,4440 (оценка)

-Температура хранения: 2-8°C

-пка: 4,78


RADIACID 0907 используется в косметических и промышленных целях для стабилизации пигментов и минеральных частиц в маслах и растворителях.
RADIACID 0907 используется в косметических рецептурах.

RADIACID 0907 может использоваться в промышленности для стабилизации минеральных частиц пигментов в маслах и растворителях.
RADIACID 0907 отличается от других жирных кислот C18 той же категории по ряду признаков.


ХИМИЧЕСКИЕ СВОЙСТВА:

-Количество доноров водородной связи: 1

- Количество акцепторов водородной связи: 2

-Количество вращающихся связей: 15

-Количество тяжелых атомов: 20

-Формальное обвинение: 0

-Сложность: 212

-Количество атомов изотопов: 0

-Определенное количество стереоцентров атома: 0

-Неопределенное количество стереоцентров атома: 0

-Определенное количество стереоцентров связи: 0

-Неопределенное количество стереоцентров связи: 0

-Ковалентно-связанные Количество единиц: 1

-Соединение канонизировано: Да


RADIACID 0907 также используется в бумажной продукции.
RADIACID 0907 представляет собой метилразветвленную жирную кислоту, представляющую собой гептадекановую кислоту (маргариновую кислоту), замещенную метильной группой в положении 16.
RADIACID 0907 используется в синтезе поли(гидроксиалканоатов) с метильным разветвлением, биосурфактантов и наночастиц серебра.

RADIACID 0907 представляет собой слаборазветвленную жидкую жирную кислоту, полученную в результате реакции олеиновой кислоты с природным минеральным катализатором. В этой реакции нет химических добавок. RADIACID 0907 на 100 % состоит из исходного масла или жира.
RADIACID 0907 представляет собой светло-желтую жидкость.

ПРИЛОЖЕНИЯ:
Синтетические смазочные материалы – RADIACID 0907 обладает хорошей термической и окислительной стабильностью.

Смазочные присадки – RADIACID 0907 представляет собой производное изостеариламида для обеспечения граничной смазки и моющих свойств.

Покрытия – RADIACID 0907 придает гибкость и долговечность промышленным покрытиям.

Металлообработка – RADIACID 0907 обладает хорошей поверхностной активностью для защитных покрытий и термической стабильностью для прокатки и штамповки.

Средства личной гигиены – RADIACID 0907 является производным изостеарилового спирта для придания ощущения и текстуры кремам и лосьонам.

RADIACID 0907 используется в составах средств личной гигиены благодаря своей функции как смягчающего средства, так и соэмульгатора.
RADIACID 0907 — это синтетически созданная жирная кислота, которая чаще всего используется в качестве связующего вещества в продуктах для ухода за кожей и в косметических продуктах, хотя она также встречается в продуктах в качестве поверхностно-активного вещества и эмульгатора.

RADIACID 0907 — уникальная жирная кислота.
RADIACID 0907 сочетает в себе лучшие свойства стеариновой кислоты с лучшими свойствами олеиновой кислоты.

RADIACID 0907 представляет собой 18-углеродную жирную кислоту с разветвленной цепью, встречающуюся в природе в растениях и животных.
Однако RADIACID 0907 представляет собой смесь многих октадекановых кислот, содержащихся в растительных и животных жирах.

RADIACID 0907 используется для загущения большинства формул в качестве связующего вещества и эмульгатора.
RADIACID 0907 представляет собой слаборазветвленную жидкую жирную кислоту, полученную в результате реакции олеиновой кислоты с природным минеральным катализатором.
RADIACID 0907 действует как мягкое, сухое смягчающее средство, способное помочь коже восполнить ее естественную влажность.

RADIACID 0907 можно легко использовать в косметике, которая не только увлажняет кожу, но и не оставляет ощущения жирности.
Тем не менее, в косметической рецептуре RADIACID 0907 используется в качестве связующего для образования компактной пудры или теней для век, напоминающей торт.
RADIACID 0907 также используется в качестве очищающего и эмульгирующего средства благодаря наличию как ионных, так и неионогенных групп.

RADIACID 0907 используется в различных косметических средствах и средствах личной гигиены.
RADIACID 0907 — это синтетически созданная жирная кислота.
RADIACID 0907 используется в качестве связующего вещества в косметических и кожных продуктах.

RADIACID 0907 — прозрачная маслянистая жидкость, которая используется в различных косметических средствах и средствах личной гигиены.
RADIACID 0907 (16-метилгептадекановая кислота) используется в синтезе поли(гидроксиалканоатов) с метильным разветвлением, биосурфактантов и наночастиц серебра.
RADIACID 0907 представляет собой жирную кислоту, которая используется в качестве смягчающего средства в фармацевтических препаратах.
Было показано, что RADIACID 0907 обладает увлажняющими и противовоспалительными свойствами кожи, что обусловлено его способностью ингибировать активность фосфолипазы А2.

RADIACID 0907 представляет собой молекулу жирной кислоты с основной цепью из 18 атомов углерода.
RADIACID 0907 представляет собой изомер стеариновой кислоты.
Химическая формула RADIACID 0907: C18H36O2.

RADIACID 0907 — это жидкая жирная кислота, созданная из олеиновой кислоты.
Заявлено, что RADIACID 0907 обладает отличным запахом, термической и окислительной стабильностью и отлично подходит для стабилизации пигментов и минеральных частиц в маслах и растворителях.

RADIACID 0907 довольно популярен в тональных кремах.
RADIACID 0907 — это наша уникальная высокоразветвленная насыщенная жирная кислота.

RADIACID 0907 имеет некоторые характеристики прозрачности и отсутствия запаха, в отличие от жирных кислот с прямой цепью.
Кроме того, RADIACID 0907 обладает отличной термостойкостью, стойкостью к окислению, способностью распределять пигмент, пеногасящими свойствами и совместим с различными органическими растворителями.

RADIACID 0907 представляет собой жирную кислоту, содержащую цепь из 18 атомов углерода.
Название IUPAC для RADIACID 0907 — октадекановая кислота.

RADIACID 0907 представляет собой раствор желтого цвета с химической формулой C18H36O2.
RADIACID 0907 представляет собой насыщенный раствор углерода.

RADIACID 0907 естественным образом содержится в мясных продуктах и растительных маслах.
Молекулярная масса RADIACID 0907 составляет 284,48 г/моль.

RADIACID 0907 растворим во многих маслах.
RADIACID 0907 используется в качестве эмульгатора или диспергатора.

RADIACID 0907 производится из возобновляемых источников и обладает такими уникальными характеристиками, как высокая стойкость к окислению и отличные свойства при низких температурах.
Области применения включают присадки или базовые компоненты для производства горюче-смазочных материалов и смягчающие средства для личной гигиены.

RADIACID 0907 представляет собой высококачественную 16-метилгептадекановую кислоту, используемую в синтезе.
Этот продукт использовался в качестве молекулярного инструмента для различных биохимических приложений.
RADIACID 0907 также использовался в широком спектре других химических и иммунологических приложений.


СИНОНИМЫ:

РАДИАКИД 0907
Радиацид 0907
Ярик I-18CG
Ярич И-18ИГ
Ярич И-18ЛГ
липонат ИСА
ИЗООКТАДЕКАНОВАЯ КИСЛОТА
изостеарный
16-МЕТИЛГЕПТАДЕКАНОВАЯ КИСЛОТА
изостеаринсур
ИЗОСТЕАРИНОВАЯ КИСЛОТА
16-метил-гептадекановая кислота
Гептадекановая кислота, 16-метил
СМЕШАННЫЕ ИЗОМЕРЫ ИЗОСТЕАРИНОВОЙ КИСЛОТЫ
Гептадекановая кислота, 16-метил-
гептадекановая кислота, 16-метил-
Ярик I-18CG
Ярич И-18ИГ
Ярич И-18ЛГ
липонат ИСА
16-метилгептадекановая кислота
16-метилмаргаровая кислота
16-метилгептадекановая кислота
изооктадекановая кислота
тюрьма 3505
тюрьма 3515
изостеариновая кислота
ИЗОСТЕАРИНОВАЯ КИСЛОТА
Изооктадекановая кислота
16-МЕТИЛГЕПТАДЕКАНОВАЯ КИСЛОТА
2724-58-5
30399-84-9
Тюрьма 3509
Гептадекановая кислота, 16-метил-
16-метилмаргаровая кислота
16-метилгептадекановая кислота
LZM5XA0ILL
ЧЕБИ:84896
(+)-изостеариновая кислота
УНИ-LZM5XA0ILL
ИНЭКС 220-336-3
16-метилмаргаровая кислота
ЭМЕРСОЛ 873
SCHEMBL15489
КЕМБЛ1865303
DTXSID1040790
16-МЕТИЛГЕПТАДЕКАНОВАЯ КИСЛОТА
ЛМФА01020014
HY-W127433
NCGC00164392-01
NCGC00164392-02
NCGC00255115-01
AS-57253
КАС-30399-84-9
CS-0185665
изостеариновая кислота
16-метилгептадекановая кислота
220-336-3
250-178-0
2724-58-5
30399-84-9
Гептадекановая кислота, 16-метил-
Изооктадекановая кислота
MFCD00044082
МИ3875000
X33R8U0062
(+)-изостеариновая кислота
16-метилмаргаровая кислота
16-метилгептадекановая кислота
16-метилмаргаровая кислота
2-метилгептадекановая кислота
2-метилгептадекановая кислота
Гептадекановая кислота, 2-метил-
λ-изостеариновая кислота
изостеариновая кислота
16-метилгептадекановая кислота
220-336-3
250-178-0
2724-58-5
30399-84-9
Кислота 16-метилгептадекановая
Гептадекановая кислота, 16-метил-
Изооктадекановая кислота
МИ3875000
X33R8U0062
(+)-изостеариновая кислота
16-метилмаргаровая кислота
16-метилгептадекановая кислота
16-метилмаргаровая кислота
2-метилгептадекановая кислота
2-метилгептадекановая кислота
Гептадекановая кислота, 2-метил-
λ-изостеариновая кислота

BABASSU OIL REFINED ;orbignya oleifera seed oil; babassu nut oil; orbignya oleifera oil; fixed oil obtained from the nuts of the babassu, orbignya oleifera, palmaceae CAS NO: 91078-92-1

CASHEW NUT OIL REFINED; cashew nutshell liquid; cashew nut shell oil; acajuba occidentalis nut shell oil; cassuvium pomiferum nut shell oil; fixed oil obtained from the seeds of the cashew, anacardium occidentale l., anacardiaceae CAS NO:8007-24-7

WHEAT GERM OIL REFINED; triticum aestivum l. germ oil; wheat germ oil; triticum vulgare germ oil; wheat husk oil; cropure wheatgerm CAS NO:68917-73-7

EVENING PRIMROSE OIL REFINED; evening primrose seed oil; cropure evening primrose; oenothera biennis seed oil; primrose seed oil ; evening primrose oil china organic; evening primrose oil organic; evening primrose seed oil; fixed oil derived from the seeds of the evening primrose, oenothera biennis, onagraceae CAS NO:65546-85-2

HAZELNUT OIL REFINED; hazelnut oil; european hazelnut oil; corylus avellana seed oil; oil expressed from the nuts of the hazelnut, corylus avellana l., betulaceae CAS NO:185630-72-2

BORAGE OIL REFINED ;borage oil organic; borage seed; fats and glyceridic oils, borage seed; cropure borage; borago officinalis seed oil cas no: 225234-12-8