HYDROXYBENZOMORPHOLINE, N° CAS : 26021-57-8, Nom INCI : HYDROXYBENZOMORPHOLINE, Nom chimique : 3,4-Dihydro-2H-1,4-benzoxazin-6-ol, N° EINECS/ELINCS : 247-415-5, Classification : Règlementé, Colorant capillaire. Ses fonctions (INCI) : Agent colorant pour cheveux : Colore les cheveux

HYDROXYCAPRIC ACID, N° CAS : 5393-81-7, Nom INCI : HYDROXYCAPRIC ACID. Nom chimique : Decanoic acid, 2-hydroxy-, (DL)-. Ses fonctions (INCI) : Agent d'entretien de la peau : Maintient la peau en bon état

Hydroxybenzotriazole; 1-Hydroxy-1H-benzotriazole; HOBt; N-Hydroxybenzotriazole; 1-Hydroxybenzotriazole; Benzazimidol; 1-Hydroxy-1,2,3-benzotriazole; 1H-Benzotriazol-1-ol; cas no: 80029-43-2

(2-Hydroxyethyl)(2-hydroxyhexadecyl)dimethylammonium chloride; HYDROXYCETYL HYDROXYETHYL DIMONIUM CHLORIDE

HYDROXYCINNAMIC ACID, N° CAS : 7400-08-0, Nom INCI : HYDROXYCINNAMIC ACID, Nom chimique : 4-Hydroxycinnamic acid; 4-Coumaric acid, N° EINECS/ELINCS : 231-000-0, Ses fonctions (INCI) : Agent d'entretien de la peau : Maintient la peau en bon état

Hydroxychloroquine; Hydroxychloroquine sulfate; Plaquenil; cas no: 118-42-3

HYDROXYCITRONELLOL, N° CAS : 107-74-4, Nom INCI : HYDROXYCITRONELLOL, Nom chimique : 3,7-Dimethyloctane-1,7-diol, N° EINECS/ELINCS : 203-517-1, Ses fonctions (INCI): Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques

Noms français : Diméthyl-3,7 hydroxy-7 octanal-1; Hydroxy-7 citronellal; Hydroxycitronellal. Noms anglais : 1-Octanal, 3,7-dimethyl-7-hydroxy-; 7-Hydroxycitronellal; Hydroxycitronellal; Laurin; HYDROXYCITRONELLAL, N° CAS : 107-75-5 - Hydroxycitronellal, Origine(s) : Synthétique, Autre langue : Hidroxicitronellal, Nom INCI : HYDROXYCITRONELLAL, Nom chimique : 7-Hydroxycitronellal, N° EINECS/ELINCS : 203-518-7, Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques

CALCIUM HYDROXIDE, N° CAS : 1305-62-0 - Hydroxyde de calcium, Nom INCI : CALCIUM HYDROXIDE, Nom chimique : Calcium dihydroxide, N° EINECS/ELINCS : 215-137-3, Additif alimentaire : E526, L'hydroxyde de calcium s'appelle aussi "chaux éteinte" ou encore "chaux hydratée". Cet élément est formé avec de l'eau et de la chaux. L'eau de chaux est l'ingrédient de base indispensable pour la réalisation des liniments oléo-calcaires. On retrouve l'hydroxyde de calcium dans les produits défrisant, il a en effet la capcité à modifier la structure du cheveux : il détruit les liaisons sulfure qui relient les acides aminés dans les mèches des cheveux et modifie leur structure physique. Pour finir, il est aussi utilisé dans certains produits en tant que régulateur de PH, étant à la base très alcalin.Régulateur de pH : Stabilise le pH des cosmétiques

STRONTIUM HYDROXIDE, N° CAS : 18480-07-4 / 1311-10-0 - Hydroxyde de strontium, Nom INCI : STRONTIUM HYDROXIDE, Nom chimique : Strontium hydroxide, N° EINECS/ELINCS : 242-367-1. Classification : Règlementé. Restriction en Europe : III/63. Régulateur de pH pour dépilatoires La concentration maximale autorisée est la suivante : 3,5 % (en strontium), PH <= 12,7 Régulateur de pH : Stabilise le pH des cosmétiques

2-hydroxyethylcelluloseether;ah15; aw15(polysaccharide); aw15[polysaccharide]; bl15; cellosize; The blood coHydroxyethyl cellulose etherngeals the appearance board; Hydroxyethyl cellulose - Viscosity 1500 ~ 2500 CAS NO: 9004-62-0

hydroxyethyl cellulose; Cellulose, hydroxyethyl ether; Hydroxyethylcellulose; 2-Hydroxyethyl cellulose; Hyetellose; Natrosol; Cellosize cas no: 9004-62-0

HYDROXYETHYL ETHYLCELLULOSE, N° CAS : 9004-58-4, Nom INCI : HYDROXYETHYL ETHYLCELLULOSE, Classification : Composé éthoxylé, Ses fonctions (INCI), Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion. Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Noms français : ETHER D'HYDROXY-2 ETHYL CELLULOSE; ETHER D'HYDROXY-2 ETHYLCELLULOSE. Noms anglais : CELLULOSE ETHYL HYDROXYETHYL ETHER; CELLULOSE, ETHYL 2-HYDROXYETHYL ETHER; ETHYL 2-HYDROXYETHYL ETHER CELLULOSE; ETHYL HYDROXY ETHYL CELLULOSE; ETHYL HYDROXYETHYL CELLULOSE; ETHYLHYDROXY ETHYL CELLULOSE; ETHYLHYDROXYETHYL CELLULOSE. Utilisation: Fabrication de produits pharmaceutiques et de laques

HYDROXYETHYL UREA, N° CAS : 1320-51-0, Nom INCI : HYDROXYETHYL UREA, Nom chimique : Urea, (2-Hydroxyethyl)-, N° EINECS/ELINCS : 215-304-0, Ses fonctions (INCI) : Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Agent d'entretien de la peau : Maintient la peau en bon état. (hydroxyethyl)urea ; Urea, N-(hydroxyethyl)-; (2-hydroxyethyl)urea; 1-(1-hydroxyethyl)urea

Hydroxyethyl Metacrylate (HEMA) Applications of Hydroxyethyl metacrylate (HEMA) Polyhydroxyethylmethacrylate is hydrophobic; however, when the polymer is subjected to water it will swell due to the molecule's hydrophilic pendant group. Depending on the physical and chemical structure of the polymer, it is capable of absorbing from 10 to 600% water relative to the dry weight. Because of this property, it was one of the first materials to be successfully used in the manufacture of soft contact lenses. When treated with polyisocyanates, poly(Hydroxyethyl metacrylate (HEMA)) makes a crosslinked polymer, an acrylic resin, that is a useful component in some paints. Poly(2-hydroxyethylmethacrylate) Properties of Hydroxyethyl metacrylate (HEMA) Poly(2-hydroxyethylmethacrylate) is an inert, water-stable, nondegradable hydrogel with high transparency. The physical properties of Hydroxyethyl metacrylate (HEMA) (e.g., swelling, stiffness, rheology) can be tuned by varying cross-linking density, incorporating different chemistries through copolymerization, and introducing mesoscopic pores. Specifically, a reduction in cross-linking density results in a softer, more malleable hydrogel that may be better suited for soft tissue regeneration. Moreover, copolymerization with acetic acid, methylmethacrylate, or dextran can adjust the permanence, hydrophilicity, and cellular adhesion in vivo. Finally, the introduction of mesoscopic porogens can facilitate vascular ingrowth, improve cellular attachment, and overcome limited permeability. Although Hydroxyethyl metacrylate (HEMA) is considered nondegradable (which makes it ideally suited for long-term applications in vivo), degradable Hydroxyethyl metacrylate (HEMA) copolymers have been fabricated by the integration of enzymatically susceptible monomers (e.g., dextran) or cross-linking agents. These degradable materials show promise for controlled release of pharmaceuticals and proteins. Applications of Hydroxyethyl metacrylate (HEMA) Due to its excellent optical properties, Hydroxyethyl metacrylate (HEMA) has primarily been used in ophthalmic applications under the generic names etafilcon A and vifilcon A. In addition, it has been examined for controlled release of proteins and drugs, engineering of cardiac tissue, axonal regeneration in spinal cord injury, and replacement of intervertebral discs. However, two limitations of Hydroxyethyl metacrylate (HEMA) are its propensity for calcification and the toxicity of the 2-hydroxyethylmethacrylate monomers. Phase I testing of Hydroxyethyl metacrylate (HEMA) for corneal prostheses (keratoprosthesis) revealed calcium salt deposition within 2.5 years after implantation. At the same time, residual Hydroxyethyl metacrylate (HEMA) monomer can compromise the mechanical properties of the hydrogel, and leach into surrounding tissue with toxic effects Because 2-hydroxyethyl methacrylate is very important in macromolecular chemistry. This paper reviews the main properties of the polymers or copolymers prepared from it by summarizing the information published in articles or patients. The following plan is adopted: Preparation and purification of 2-hydroxyethyl methacrylate Polymerization and copolymerization of 2-hydroxyethyl methacrylate and physical properties Chemical modifications of monomer Chemical modifications of poly-2-hydroxyethyl methacrylate and related copolymers Grafting reactions of polymer or copolymer Applications in biomedical fields The following abbreviations will be used: Hydroxyethyl metacrylate (HEMA) for 2-hydroxyethyl methacrylate (rather than GMA, which is chiefly employed in medical journals) and Hydroxyethyl metacrylate (HEMA) for the corresponding polymers. EGDMA will be used for ethylene glycol dimethacrylate, an impurity synthesized in the preparation of monomer. Hydroxyethyl metacrylate (HEMA) is perhaps the most widely studied and used neutral hydrophilic monomer. The monomer is soluble, its homopolymer is water-insoluble but plasticized and swollen in water. This monomer is the basis for many hydrogel products such as soft contact lenses, as well as polymer binders for controlled drug release, absorbents for body fluids and lubricious coatings. As a co-monomer with other ester monomers, Hydroxyethyl metacrylate (HEMA) can be used to control hydrophobicity or introduce reactive sites. 2-Hydroxyethyl methacrylate is perhaps the most widely studied and used neutral hydrophilic monomer. The monomer is soluble, its homopolymer is water-insoluble but plasticized and swollen in water. This monomer is the basis for many hydrogel products such as soft contact lenses, as well as polymer binders for controlled drug release, absorbents for body fluids and lubricious coatings. As a co-monomer with other ester monomers, Hydroxyethyl metacrylate (HEMA) can be used to control hydrophobicity or introduce reactive sites. glycol methacrylate Technical grade: Purity %=min. 97; Acid Content %=max 1.5; EGDMA content %=max 0.2; Color=50 Because 2-hydroxyethyl methacrylate is very important in macromolecular chemistry. This paper reviews the main properties of the polymers or copolymers prepared from it by summarizing the information published in articles or patients. The following plan is adopted: Preparation and purification of 2-hydroxyethyl methacrylate Polymerization and copolymerization of 2-hydroxyethyl methacrylate and physical properties Chemical modifications of monomer Chemical modifications of poly-2-hydroxyethyl methacrylate and related copolymers Grafting reactions of polymer or copolymer Applications in biomedical fields The following abbreviations will be used: Hydroxyethyl metacrylate (HEMA) for 2-hydroxyethyl methacrylate (rather than GMA, which is chiefly employed in medical journals) and Hydroxyethyl metacrylate (HEMA) for the corresponding polymers. EGDMA will be used for ethylene glycol dimethacrylate, an impurity synthesized in the preparation of monomer. method is the reaction of ethylene oxide and methacrylic acid. The Hydroxyethyl metacrylate (HEMA) prepared by these two methods contains impurities in various percentages: e.g., methacrylic acid results from a hydrolysis reaction of Hydroxyethyl metacrylate (HEMA) and EGDMA coming from esterification between methacrylic acid or Hydroxyethyl metacrylate (HEMA) and ethylene glycol. Since Hydroxyethyl metacrylate (HEMA) is a commercial product, it seems more useful to summarize the various purification procedures rather than the numerous works about industrial preparations because the commercial product contains EGDMA and methacrylic acid in monomer proportions. The main procedures use the solubility of Hydroxyethyl metacrylate (HEMA) in water or diethyl ether and its nonsolubility in hexane. EGDMA is soluble in hexane. Therefore, Hydroxyethyl metacrylate (HEMA) is dissolved in four volumes of water and EGDMA is extracted with hexane. Then the aqueous solution of Hydroxyethyl metacrylate (HEMA) is salted to complex methacrylic acid. Hydroxyethyl metacrylate (HEMA) is extracted with diethyl ether, the solution is dried, and Hydroxyethyl metacrylate (HEMA) is distilled under vacuum. The elimination of methacrylic acid can also be carried out by soaking technical Hydroxyethyl metacrylate (HEMA) with anhydrous sodium carbonate and extracting EGDMA with hexane. Then Hydroxyethyl metacrylate (HEMA) is extracted with diethyl ether and distilled as previously described. The use of ion-exchange resins (Amberlyst A 21) is a simple method of elimination of methacrylic acid but the yield is rather poor. N,N'-Dicyclohexylcarbodiimide has also been used for the elimination of methacrylic acid, but variations in the quality of the reagent often outweigh the value of the method. Lastly, extraction of EGDMA with hexane followed by the washing of a dilute solution of Hydroxyethyl metacrylate (HEMA) in water with sodium hydroxyde or sodium bicarbonate and the extraction of Hydroxyethyl metacrylate (HEMA) with chloroform gives, after drying and evaporation of chloroform, a product of high purity for the preparation of resins for optical microscopy. The purity of the monomer can be checked by using vapor-phase chromatography, liquid chromatography, or thin layer chromatography. Detailed distillation procedures to avoid polymerization of Hydroxyethyl metacrylate (HEMA) have been described. Polymerization As for the majority of methacrylic derivatives, Hydroxyethyl metacrylate (HEMA) can be polymerized by radical initiators or by various methods (y-rays, UV, and plasma). When the monomer is purified (without EGDMA, which is a crosslinking product), a soluble polymer can be synthesized, but when the monomer contains even a low percentage of EGDMA, the prepared copolymers produce swollen gels in water and in many other solvents A summary of the main procedures of polymerization is given in Table 1. Syndiotactic Hydroxyethyl metacrylate (HEMA) has been synthesized by UV catalysis at - 40"C, and isotactic Hydroxyethyl metacrylate (HEMA) has been prepared through hydrolysis of poly(benzoxyethy1 methacrylate) which had been synthesized from the corresponding polymers with dibutyl lithium cuprate as catalyst. Physical Properties of Hydroxyethyl metacrylate (HEMA) Because Hydroxyethyl metacrylate (HEMA) has numerous applications in biomedicine, its physical properties have been widely studied. Studies of Diffusion. The permeability of Hydroxyethyl metacrylate (HEMA), used as a membrane for oxygen, has been compared to other macromolecules. The diffusion of water through hydrogels of Hydroxyethyl metacrylate (HEMA), crosslinked with low percentages of EGDMA, has also been studied. The influence of the degree of crosslinking, the diffusion laws, the measurement of the equilibrium constant with water, and a structural study of swollen gels were recently published. Mechanical and Viscoelastic Properties. These properties were summarized in two previous reviews. Composites with crosslinked Hydroxyethyl metacrylate (HEMA) have good elastic properties. The influence of aqueous solutions of sodium chloride on the elasticity of Hydroxyethyl metacrylate (HEMA) has also been studied in relation to its use for optical lenses. Viscometry, Thermal, and Dielectric Properties, and NMR Characterizations. Because the Mark-Houwink parameters in many solvents are well known, the molecular weights of Hydroxyethyl metacrylate (HEMA) can be measured by viscosity. Lastly, in order to use the Hydroxyethyl metacrylate (HEMA) in the biomedical field, the purification of polymer gel has been described. Copolymerization Reactions of Hydroxyethyl metacrylate (HEMA) Copolymerization reactions of this monomer have been studied for its fundamental properties (determination of reactivity ratios, AlfreyPrice parameters) and its applications in various fields. Some examples of block copolymerization with styrene, 2- phenyl-1,2,3-dioxaphospholane, and with macromonomers of polyamine or polyurethane can be cited. Lastly, fundamental studies on the copolymerization of methyl methacrylate with Hydroxyethyl metacrylate (HEMA) and the determination of the composition of its copolymer have been made, and a model of the copolymerization of Hydroxyethyl metacrylate (HEMA) and EDGMA was recently published. Because Hydroxyethyl metacrylate (HEMA) has a primary alcohol function a great number of nucleophilic reactions have been achieved and generally the modified monomer can be polymerized. CHEMICAL MODIFICATIONS OF Hydroxyethyl metacrylate (HEMA) AND RELATED COPOLYMERS A relatively low number of chemical modifications of Hydroxyethyl metacrylate (HEMA) have been registered because chemical modifications of the corresponding monomer as well as its polymerization are easy to achieve. GRAFTING REACTIONS OF POLYMER AND COPOLYMER By using various techniques, the grafting of Hydroxyethyl metacrylate (HEMA) and copolymers prepared with Hydroxyethyl metacrylate (HEMA) as a comonomer has been carried out with natural polymers such as cellulose, dextran, and starch. APPLICATIONS IN BIOMEDICAL FIELDS Because Hydroxyethyl metacrylate (HEMA) can be easily polymerized, possesses a hydrophilic pendant group, and can form hydrogels, an increasing number of applications have been found in various biomedical fields. Although, as previously mentioned, a complete listing of the literature references appears impossible, we have tried to present the main areas of interest for Hydroxyethyl metacrylate (HEMA), either when used alone or in combination with other chemical reagents. 7.1. Irritant and Toxic Effects First of all, the low toxicity of the monomer is widely accepted but few reports are available on the (potent) irritant effects of Hydroxyethyl metacrylate (HEMA). Intradermal injection of crude Hydroxyethyl metacrylate (HEMA) monomer at low concentrations in saline solution (-1%) was found to induce a very mild irritation in the rat, while higher concentrations (up to 20%) were associated with a pronounced reaction. Similar findings were observed with sodium benzoate (an end product of benzoyl peroxide degradation used as a polymerization initiator) emphasizing the irritant role of residues. Hydroxyethyl metacrylate (HEMA) gels implanted into muscles of rats were found to release residual irritant continuously but at a very low rate, thus inducing no cellular reaction. Hydroxyethyl metacrylate (HEMA) used at 0.01-1% concentrations was found to alter the fine structure of cultured cells with quantitative video microscopy. On the other hand, numerous clinical trials, listed hereafter within a specific organ description, have found minimal irritant reactions. Histological Embedding The use of Hydroxyethyl metacrylate (HEMA) in histological practice (i.e., the study of living tissues and cells at the microscopic level) was proposed by Rosenberg and Wichterle (1631. The hydrophilic properties of the monomer permit it to be used as a combined dehydrating agent for the tissues and as an embedding medium for electron microscopy. 2-HYDROXYETHYL METHACRYLATE 15 of pure Hydroxyethyl metacrylate (HEMA) appeared difficult to section, and they had poor resistance under an electron beam. The quality of commercially available Hydroxyethyl metacrylate (HEMA) was reported to vary considerably up to 1965. Copolymers with n-butyl methacrylate or styrene were also found less satisfactory than the epoxy resins. During the last decade, Hydroxyethyl metacrylate (HEMA) has found a new interest in light microscopy. An extensive review was made by Bennett et al. "1. Briefly, Hydroxyethyl metacrylate (HEMA) embedding is favored for light microscopy because: 1) The embedding duration is shorter than for classical methods. Hydroxyethyl metacrylate (HEMA) was used to embed large and very large specimen. 2) Preservation of tissular and cellular structures is far superior to other classical methods. This is due to the adherence of tissue sections onto the microscopic glass slides and because the resin is not removed prior to staining. 3) Sectioning is easier and semithin sections (i.e., 2 to 3 pm in thickness) can be obtained on conventional microtomes with steel or Ralph's glass knives. Furthermore, once cut, the sections spread on water and do not shrink. 4) Numerous staining methods can be performed on Hydroxyethyl metacrylate (HEMA) sections. Classical stains (excepted those having a hydro-alcoholic vehicle which makes the section swell) have been reported to work well, sometimes after minor modifications. Enzymological studies can readily be done, and large amounts of enzymes are preserved. Calcified tissue enzymes have been demonstrated on undecalcified sections. At the present time, several Hydroxyethyl metacrylate (HEMA)-based commercial kits are available. However, the slow hydrolysis of the resin makes it difficult to obtain regular results; the regenerated methacrylic acid appears to combine with basic stains, and small amounts (1.5% or less) impair correct staining by strongly obscuring the background. Several purification methods specially devoted to histotechnology have been designed. Copolymerization with dimethylamino ethyl methacrylate was proposed to complex the carboxylic groups of methacrylic acid. Hydroxyethyl metacrylate (HEMA) alone was repeatedly found to be a poor medium for calcified tissues because the size of the molecule makes it difficult to infiltrate such tissues. Combined with methyl methacrylate (MMA) or various types of aikyl methacrylates or acrylates, Hydroxyethyl metacrylate (HEMA) was shown to provide suitable embedding media. Hydroxyethyl metacrylate (HEMA) is usually polymerized by a redox reaction (benzoyl peroxide and N,N‘-dimethyl aniline), and the method has been used to embed in the cold, thus preserving enzyme activities. MONTHEARD, CHATZOPOULOS, AND CHAPPARD they induce staining artifacts. Other initiators have also been proposed (barbiturate cyclo compounds, butazolidine). Hydroxyethyl metacrylate (HEMA) has been shown to produce better sections when small amounts of crosslinkers are used. We recently showed that Hydroxyethyl metacrylate (HEMA) embedding is an inhomogeneous mechanism and that it varies according to the volume of monomer to be bulk polymerized. Dentistry Synthetic apatitic calcium phosphate cements were prepared with a Hydroxyethyl metacrylate (HEMA) hydrogel containing tetracalcium phosphate and dicalcium phosphate. Hydroxyethyl metacrylate (HEMA) was found to be a highly biocompatible and resorbable material for primary teeth endodontic filling. However, due to its hydrophilicity, Hydroxyethyl metacrylate (HEMA) appeared more useful in dentistry as a bonding reagent between dentine and other types of restorative resins; varying mixtures of Hydroxyethyl metacrylate (HEMA) and glutaraldehyde were investigated. Other bonding complexes using Hydroxyethyl metacrylate (HEMA) have been reported for enamel and dentine. Hydroxyethyl metacrylate (HEMA) was found to be a suitable vehicle for dentin self-etching primers (such as acidic monomers). Other clinical trials have been done with an antiseptic (chlorhexidine) entrapped in a Hydroxyethyl metacrylate (HEMA)/MMA copolymer membrane to develop a controlled release delivery system. However, Hydroxyethyl metacrylate (HEMA) was found unsuitable as a permanent soft lining material for covering the oral mucosa in denture-bearing areas. Immobilization of Molecules and Cells Immobilization implies the entrapment within a polymeric network of a definite "foreign" compound (i.e., an enzyme, a drug, a cell, . . .), whether it is simply confined or grafted onto the polymeric chains. The ability of various drugs to diffuse into polymers may be used in various types of biotechnologies such as membrane separation and drug delivery devices. The prediction of drug solubilities in Hydroxyethyl metacrylate (HEMA) and other polymers has been studied. Immobilization of chloramphenicol in Hydroxyethyl metacrylate (HEMA) hydrogels crosslinked with EGDMA was found to be released upon swelling of the gel in water; the diffusion obeyed Fick's second law. The kinetics of thiamine (vitamin B1) diffusion from previously loaded Hydroxyethyl metacrylate (HEMA) beads was studied at 37.5"C in water. Theophyllin release from an amphiphilic composite made of Hydroxyethyl metacrylate (HEMA) and polyisobutylene was studied from a kinetic point of view. Hydroxyethyl metacrylate (HEMA) membranes are favored as transdermal delivery systems for long-term constant drug delivery. Vidarabine (an antiviral agent) was entrapped to Hydroxyethyl metacrylate (HEMA) membranes and used for transdermal patches: the blood-drug concentrations could be predicted and the permeability coefficient of the membranes could be adjusted by controlling hydration. Similar observations were obtained with progesteron. Nitroglycerin was also entrapped in Hydroxyethyl metacrylate (HEMA) membranes to provide a transdermal delivery system. Synthetic organ substitutes having the capacity to slowly release hormones have been designed: diffusivity of insulin through Hydroxyethyl metacrylate (HEMA) membranes was studied. Because Hydroxyethyl metacrylate (HEMA) hydrogels are hardly degraded in vivo, it was found that entrapment of drugs (testosterone) in a blend of Hydroxyethyl metacrylate (HEMA)/albumin resulted in a slowly degraded matrix with continuous release of the drug. Testicular prosthesis releasing testosterone have been done. Anticancer drugs have been extensively entrapped in matrices of Hydroxyethyl metacrylate (HEMA), thus providing a hard material which can be implanted into the tumor where it delivers higher amounts of drug in situ. 5- Fluorouracil was embedded in Hydroxyethyl metacrylate (HEMA)/bisglycol acrylate copolymer in 3 mm diameter beads which could be implanted subcutaneously. Methotrexate and 3'3'-dibromoaminopterin were absorbed on Hydroxyethyl metacrylate (HEMA) and used as local intratumoral implants in Gardner's lymphosarcoma of the C3H mouse. The effect of crosslinking on the swelling of Hydroxyethyl metacrylate (HEMA) gels (and the drug diffusion coefficient through these gels) has been explored. Finally, various substances have been immobilized in Hydroxyethyl metacrylate (HEMA) in order to prepare diagnostic tools. An antiserum-raised methotrexate was entrapped in Hydroxyethyl metacrylate (HEMA) during polymerization. The lyophilized powder was used for radioimmunoassay of this anticancer drug. The entrapment of immunoglobulins has been used for immunochemical studies. The Fc fragment of immunoglobulins has been grafted onto Separon Hydroxyethyl metacrylate (HEMA) resins after periodate oxidation, thus providing immuno-affinity sorbents for the isolation of proteins. A dye, Cibracron Blue F3GA, was entrapped within the pores of a nylon/ Hydroxyethyl metacrylate (HEMA) gel used for protein purification. Biocompatibility of Hydroxyethyl metacrylate (HEMA) Biocompatibility of Hydroxyethyl metacrylate (HEMA) has been studied at the cell and tissue levels. Cell cultures on Hydroxyethyl metacrylate (HEMA)-coated slides or on Hydroxyethyl metacrylate (HEMA) hydrogels are used to investigate the intimate mechanisms of cellular compatibility. Implanting pieces of gel in an animal by a surgical procedure allows the study of the adverse reactions of the whole organisms against the resin. Because implantations in the eye or in direct contact with blood induces specific problems, these two aspects of the biocompatibility will be treated separately below. Cell Culture The hydrophilicity of the resin was primarily thought to be favorable for cell culture. Cellular adherence to Hydroxyethyl metacrylate (HEMA) has been recognized since 1975 when myoblasts from chicken embryos were cultured on polysiloxane grafted with Hydroxyethyl metacrylate (HEMA). Spreading of cells of hamster kidney was found higher on modified Hydroxyethyl metacrylate (HEMA) than on polystyrene due to the hydrophilic properties of the resin. Similar experiments done with endothelial cells of newborn cords have shown that cells first adhere to the hydrophilic substrate, then spread and proliferate. However, pure and unmodified Hydroxyethyl metacrylate (HEMA) appears unable to support attachment and growth of mammalian cells. Implants Hydroxyethyl metacrylate (HEMA) is a suitable biomaterial for implantation because of its lack of toxicity and high resistance to degradation. Numerous composite biomaterials based on Hydroxyethyl metacrylate (HEMA) and collagen blends have been used. By using various additives, the mechanical properties of Hydroxyethyl metacrylate (HEMA) hydrogels can be adjusted to various biomedical applications. Hydroxyethyl metacrylate (HEMA)/methacrylic acid copolymers were found more biocompatible than Hydroxyethyl metacrylate (HEMA) alone which induces a giant cell inflammatory reaction when implanted. When collagen was entrapped in Hydroxyethyl metacrylate (HEMA) gels, their composites were found highly biocompatible when implanted subcutaneously in rats. Composites with a low collagen content were found to be better preserved in long-term implantation studies whereas those containing higher amounts of collagen exhibited calcification in the early stages, followed by full biodegradation. Calcification of a synthetic biomaterial implies poor biocompatibility. Although the chemical composition appears important, the macroscopic structure and surface characters of a Hydroxyethyl metacrylate (HEMA) implant have been shown to play a key role. 2-HYDROXYETHYL METHACRYLATE 21 of calcification; in addition, hydrogels of Hydroxyethyl metacrylate (HEMA) and methacrylic acid copolymers were found to pick up large amounts of Ca2+ when exposed to aqueous solutions of calcium. This effect was taken into account when porous sponges of Hydroxyethyl metacrylate (HEMA) were compared to demineralized bone for inducing ectopic bone formation. Hydrogels of Hydroxyethyl metacrylate (HEMA) have an excellent biocompatibility but present poor mechanical properties. The mechanical and hydration properties of Hydroxyethyl metacrylate (HEMA) and other polyhydroxyalkyl methacrylate membranes have been studied. Composites of silicone rubber and fine particles of hydrated Hydroxyethyl metacrylate (HEMA) were found to combine both advantages. Radiation grafting of Hydroxyethyl metacrylate (HEMA) was done on polyurethane films (with good mechanical properties) and found to increase hydrophilicity and tolerance. Hydroxyethyl metacrylate (HEMA) was grafted on polyether urethane area membranes used for hemodialysis; permeability and blood tolerance were improved but tensile strength was reduced. Hemodialysis membranes of Hydroxyethyl metacrylate (HEMA) crosslinked with ethylene dimethacrylate have been prepared. The interaction of urea (the end product of protein catabolism) with Hydroxyethyl metacrylate (HEMA) hydrogels revealed that small amounts of methacrylic acid may dramatically increase the swelling properties of the gel. Prosthetic Vascular Implants and Blood Compatibility A very interesting property of Hydroxyethyl metacrylate (HEMA)-based hydrogels is their high hemocompatibility. In the presence of blood, thrombus formation is delayed. Because blood is a complex milieu, in this paragraph we consider all the relationships of Hydroxyethyl metacrylate (HEMA) with blood cells, endothelial cells (i.e., the inner cells of the blood vessels), orland blood components. Due to the hydrophilicity of Hydroxyethyl metacrylate (HEMA), films of styrene-butadiene-styrene had a better blood compatibility when grafted with Hydroxyethyl metacrylate (HEMA). Copolymers of Hydroxyethyl metacrylate (HEMA)/styrene or Hydroxyethyl metacrylate (HEMA)/dimethyl siloxane suppress platelet adhesion and aggregation (and thus reduce thrombus formation) by the creation of hydrophilic/hydrophobic microdomains. Similar findings were obtained with Hydroxyethyl metacrylate (HEMA)/polyethylene oxide and Hydroxyethyl metacrylate (HEMA)/ polypropylene oxide copolymers. A Hydroxyethyl metacrylate (HEMA)-polyamine copolymer was found to induce no blood platelet adherence or activation. Also, this copolymer was used to separate T from B lymphocytes subpopulations via its hydrophilic-hydrophobic microdomain compositio. Vascular tubes of polyethylene Blended with 14% Hydroxyethyl metacrylate (HEMA) have a very low thrombogeneity due to hydrophilization of the plastic. Radiation grafting of Hydroxyethyl metacrylate (HEMA) and N-vinyl pyrrolidone on silicone rubber was used to improve the hydrophilicity of artery-to-vein shunts and thus to reduce thrombus formation. A highly antithrombogenic polymer was prepared by immobilizing the fibrinolytic enzyme urokinase in a Hydroxyethyl metacrylate (HEMA) hydrogel. Another important aspect of blood compatibility is the power of a biomaterial to activate the complement system. It is a complex system of plasma proteins activated in cascade and involved in the inflammation process. Intraocular lenses made of Hydroxyethyl metacrylate (HEMA) were found ineffective in vifro to activate the serum complement system (C3a, C4a, C5a). Hydroxyethyl metacrylate (HEMA)-grafted polyethylene tubes were not found to inactivate the complement. On the other hand, copolymers of Hydroxyethyl metacrylate (HEMA)/ethyl methacrylate were reported to activate the complement when the polymer contained 60% or more Hydroxyethyl metacrylate (HEMA). Low density lipoprotein adsorption on Hydroxyethyl metacrylate (HEMA) was found to be low due to the hydrophilicity of the resin. Particles of Hydroxyethyl metacrylate (HEMA) were used to study the phagocytic processes of macrophages and neutrophils. The hemocompatibility of Hydroxyethyl metacrylate (HEMA) has led to the development of a medical method used to remove endo or exo toxins from blood. Hemoperfusion takes advantage of activated charcoal to bind such toxics (barbiturates, tricyclic antidepressants). Activated carbon particles have been encapsulated with Hydroxyethyl metacrylate (HEMA) for the construction of hemoperfusion columns; heparinized blood is purified by adsorption of irrelevant toxic molecules onto the entrapped charcoal particles and the cleaned blood is then perfused to the patient. Composites of Hydroxyethyl metacrylate (HEMA), PEG, and activated carbon were found useful for other blood perfusion applications. Another important application of Hydroxyethyl metacrylate (HEMA) is the occlusion of blood vessels in various organs and principally in tumors (which are always hypervascularized). Spherical particles of Hydroxyethyl metacrylate (HEMA) of regular shape were produced by suspension polymerization. When injected in a vessel close to the tumor, the small beads act as emboli and obliterate the smaller vessels. Thus tumor vascularization is stopped and endovascular embolization is followed by tumoral cell necrosis and size reduction of the tumor. The swelling in water of Hydroxyethyl metacrylate (HEMA) beads makes them suitable to close obliteration of vessels. Detailed procedures have been published for preparing such porous Hydroxyethyl metacrylate (HEMA) beads of regular size suitable as artificial thrombi. Optical Lenses The main application of Hydroxyethyl metacrylate (HEMA) hydrogels is the preparation of contact and intraocular lenses used after cataract extraction. Black pigmented Hydroxyethyl metacrylate (HEMA) was used to prepare light-occluding lens after opthalmic surgery. Gentamicin-soaked contact lenses made of a 61.4% Hydroxyethyl metacrylate (HEMA) hydrogel were found to retain bactericidal concentrations of the antibiotic up to 3 days of eye contact. Diffusion of oxygen through hydrophilic contact lens is necessary to avoid corneal oedema. With Hydroxyethyl metacrylate (HEMA) lenses, this is obtained with a 33-pm thickness. Deep corneal stromal opacities were seen in Hydroxyethyl metacrylate (HEMA) contact lenses and were related to chronic corneal anoxia. Deposits are sometimes observed within contact lenses. They occur after 12 months of daily lens wear and may be associated with vision decrement. The protein deposits on contact lenses vary according to the copolymer: With Hydroxyethyl metacrylate (HEMA)Imethacrylic acid copolymers, lenses absorb large amounts of lysosyme, and Hydroxyethyl metacrylate (HEMA) IMMA copolymer preferentially adsorbs albumin. Contact lenses of copolymers of Hydroxyethyl metacrylate (HEMA) with methacrylic acid or various silanes were found to adsorb less lysosyme than unsilanized lenses. Deposits of calcium in contact lens made of Hydroxyethyl metacrylate (HEMA) have been reported. Intraocular strips of Hydroxyethyl metacrylate (HEMA) hydrogels containing small amounts (1.2-1.4%) of methacrylic acid were found to be favorably tolerated in vivo due to the high water and carboxylic group content. Hydroxyethyl metacrylate (HEMA) intraocular lens were found to be better tolerated than conventional amino-polyamide-base implants, but the presence of microvilli on corneal cells suggests the release of impurities from the resin. Hydroxyethyl metacrylate (HEMA)-based intraocular lenses were found to be well preserved after Nd:YAG laser surgery. Various drugs (chloramphenicol, pilocarpine, dexamethasone) were found to have a longer washout period when entrapped in intraocular lenses than in the human lens. The clinicobiological results of Hydroxyethyl metacrylate (HEMA) intraocular lenses were found to be the most favorable, with 92% of implanted patients recovering visual acuity.

2-hydroxyethylurea urea, (2-hydroxyethyl)- urea, N-(hydroxyethyl)- CAS Number 1320-51-0

HYDROXYETHYL-2-NITRO-P-TOLUIDINE N° CAS : 100418-33-5 Nom INCI : HYDROXYETHYL-2-NITRO-P-TOLUIDINE Nom chimique : 1-Methyl-3-nitro-4-(.beta.-hydroxyethyl)aminobenzene N° EINECS/ELINCS : 408-090-7

cas no: 34206-40-1 TOS in Toluene; Einecs 251-882-0; Tetrakis-butanonoximsilan(TOS); Tetra(butanone oximido) silane; Tetra(methyiethylketoxime)silane; tetra-(methylethylketoxime)silane; 2BUTANEOOOOSILANETETRAYLTETRAOXIME; TETRA(METHYL ETHYL KETOXIMO)SILANE; Tetra (MEKO) silane in Toluene; TETRAKIS(METHYLETHYLKETOXIMINO)SILANE

HYDROXYETHYLCELLULOSE,Tylose, N° CAS : 9004-62-0, Nom INCI : HYDROXYETHYLCELLULOSE, Classification : Composé éthoxylé, L'hydroxyéthylcellulose est un polymère obtenu par l'action d'oxyde d'éthylène sur de la cellulose. Il est utilisé en cosmétique en tant qu'épaississant.Ses fonctions (INCI). Agent fixant : Permet la cohésion de différents ingrédients cosmétiques Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion. Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Agent stabilisant : Améliore les ingrédients ou la stabilité de la formulation et la durée de conservation. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Noms français : Cellulose, hydroyéthyl de; Hydroxy-2 éthyl cellulose. Noms anglais : 2-Hydroxyethyl cellulose; 2-HYDROXYETHYL CELLULOSE ETHER; CELLULOSE HYDROXYETHYL ETHER; CELLULOSE HYDROXYETHYLATE; CELLULOSE, 2-HYDROXYETHYL ETHER; CELLULOSE, ETHYLENE OXIDE-GRAFTED;HYDROXY ETHYL CELLULOSE HYDROXYETHYL CELLULOSE; HYDROXYETHYL CELLULOSE ETHER; HYDROXYETHYL ETHER CELLULOSE; HYDROXYETHYLCELLULOSE; OXIRANE, POLYMER WITH CELLULOSE Utilisation : Agent épaississant, fabrication de produits pharmaceutiques

2-HYDROXYETHYL CELLULOSE; CELLOSIZE WP-40; CELLULOSE, 2-HYDROXYETHYL ETHER; CELLULOSE, HYDROXYETHYL ETHER; HEC; HYDROXYETHYL CELLULOSE; HYDROXYETHYL-CELLULOSE 140'000-160'000; HYDROXYETHYL-CELLULOSE DYED WITH OSTAZIN BRILLIANT RED H-3B; Hydroxyethyl cellulose ether; 2-hydroxyethylcelluloseether; ah15; aw15(polysaccharide); aw15[polysaccharide]; bl15; cellosize; cellosize4400h16; cellosizeqp; cellosizeqp1500; cellosizeqp3; cellosizeqp30000 CAS NO:9004-62-0

N-(2-Hydroxyethyl)ethylenediamine-N,N′,N′-triacetic acid; N-Carboxymethyl-N′-(2-hydroxyethyl)-N,N′-ethylenediglycine, HEDTA, HEEDTA cas no: 150-39-0

Cellulose,2-hydroxyethylmethylether;'Tylose'® MH 300;Hydroxythyl Methyl Cellulose;HydroxythylMethylCellulose(Hemc);HEMC;HYDROETHYLMETHYL CELLULOSE (HEMC);METHYL HYDROXYETHYL CELLULOSE (20-40CPS: 2% IN WATER);Methyl Hydroxyethyl Cellulose (20-40mPa.s, 2% in Water at 20deg C) CAS NO:9032-42-2

HYDROXYETHYL-P-PHENYLENEDIAMINE SULFATE N° CAS : 93841-25-9 Nom INCI : HYDROXYETHYL-P-PHENYLENEDIAMINE SULFATE Nom chimique : 3-(2-Hydroxyethyl)-p-phenylenediammonium sulphate/ Hydroxyethyl-p- Phenylenediamine Sulfate N° EINECS/ELINCS : 298-995-1

caprylic/capric acid ester of saturated fatty alcohol C12-C18; fatty acids C12-18 C8-10-alkyl esters; fatty acids, C12-18, C8-10-alkyl esters cas no: 95912-86-0

HYDROXYLAMINE SULPHATE; Hydroxylammonium sulfate; Hydroxylamine, sulfate (2:1) (salt); bis(hydroxylamine) sulfate; hydroxylamine neutral sulfate; bis(hydroxylammonium) sulfate; Hydroxylamine sulfate; cas no: 10039-54-0

Hydroxylamine Sulfate; Hydroxylamine, sulfate (2:1) (salt); bis(hydroxylamine) sulfate; hydroxylamine neutral sulfate; bis(hydroxylammonium) sulfate; Hydroxylamine sulfate; OXAMMONIUM SULFATE cas no: 10039-54-0

HA HCL; HOHCL; HYDROXYAMMONIUM CHLORIDE; HYDROXYLAMINE HCL; HYDROXYLAMINE/HCL SOLUTION; HYDROXYLAMINE HYDROCHLORIDE; HYDROXYLAMMONIUM CHLORIDE; OXAMMONIUM HCL; OXAMMONIUM HYDROCHLORIDE; hydroxyaminehydrochloride; hydroxylaminechloride; hydroxylaminechloride(1:1); Oxammionium; HYDROXYLAMINE HYDROCHLORID; HYDROXYLAMINE HYDROCHLORIDE, FOR AAS; Hydroxylamine hydrochloride, 99.999% metals basis; HYDROXYLAMINE HYDROCHLORIDE REAGENTPLU&; HYDROXYLAMINE HYDROCHLORIDE, 99%, A.C.S. REAGENT; Hydroxylamine hydrochloride, 99.9999% metals basis; HYDROXYLAMINE HYDROCHLORIDE ACS REAGENT CAS NO:5470-11-1

SYNONYMS Hydroxylammonium sulfate; Hydroxylamine, sulfate (2:1) (salt); bis(hydroxylamine) sulfate; hydroxylamine neutral sulfate; bis(hydroxylammonium) sulfate; Hydroxylamine sulfate;OXAMMONIUM SULFATE CAS NO. 10039-54-0

HYDROXYLATED LECITHIN, N° CAS : 8029-76-3., Nom INCI : HYDROXYLATED LECITHIN, N° EINECS/ELINCS : 232-440-6. Ses fonctions (INCI): Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Agent d'entretien de la peau : Maintient la peau en bon état. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

SODIUM HYDROXYMETHYLGLYCINATE N° CAS : 70161-44-3 - Hydroxymethylglycinate de sodium Origine(s) : Synthétique Nom INCI : SODIUM HYDROXYMETHYLGLYCINATE Nom chimique : Sodium N-(hydroxymethyl)glycinate N° EINECS/ELINCS : 274-357-8. L'hydroxymethylglycinate de sodium est utilisé en tant que conservateur en cosmétique comme alternative aux parabènes. Il agit à lui seul sur un spectre assez large de microbes et bactéries en tout genre.Ses fonctions (INCI) Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétiques

HYDROXYPHENOXY PROPIONIC ACID, N° CAS : 94050-90-5, Nom INCI : HYDROXYPHENOXY PROPIONIC ACID, Nom chimique : (R)-2-(4-hydroxyphenoxy)propanoic acid, N° EINECS/ELINCS : 407-960-3. Ses fonctions (INCI) : Agent d'entretien de la peau : Maintient la peau en bon état

HYDROXYPHENYL PROPAMIDOBENZOIC ACID, N° CAS : 697235-49-7, Nom INCI : HYDROXYPHENYL PROPAMIDOBENZOIC ACID, Nom chimique : Benzoic Acid, 2-[[(3-(4-Hydroxyphenyl)-1-Oxopropyl]Amino]-, Ses fonctions (INCI) : Agent d'entretien de la peau : Maintient la peau en bon état

HPAA; HPA; Belcor 575; 2-Hydroxy Phosphono Acetic Acid; CAS NO:23783-26-8

HPAA; HPA; Belcor 575; 2-Hydroxy Phosphono Acetic Acid; CAS NO:23783-26-8

SynonymsHPA;HPAA;HPSE;HPSE1;Belcor 575;Heparanase-1;Snailagglutinin;Endo-glucoronidase;Phosphonoglycolic acid;Heparanase CAS No.23783-26-8

HYDROXYPROLINE, N° CAS : 51-35-4, Nom INCI : HYDROXYPROLINE, Nom chimique : L-4-hydroxyproline, N° EINECS/ELINCS : 200-091-9. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Agent d'entretien de la peau : Maintient la peau en bon état. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

(2-Hydroxyethyl)(2-hydroxyhexadecyl)dimethylammonium chloride; HYDROXYCETYL HYDROXYETHYL DIMONIUM CHLORIDE

Hydroxypropyl cellulose - Average MW 1,000,000;Low-Substituted Hydroxypropyl cellulose;HYDROXYPROPYLCELLULOSE, M.W.60,000;oxypropylatedcellulose;pm50;pm50(polymer);syntheticvegetablegums;HYDROXYPROPYL CELLULOSE CAS NO: 9004-64-2

HYDROXYPROPYL DISTARCH PHOSPHATE; Hydroxypropyl di-starch phosphate; Hydroxypropylated distarch phosphate cas no: 53124-00-8

HYDROXYPROPYL GUAR, N° CAS : 68442-94-4 / 39421-75-5, Nom INCI : HYDROXYPROPYL GUAR, N° EINECS/ELINCS : 270-497-9 / - Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion.Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques

Guar gum, 2-hydroxypropyl ether; gum guar 2-hydroxypropyl ether; Hydroxypropyl guar gum; guar gum, propoxylated; 2-Hydroxypropyl guar gum;HYDROXYPROPYL GUAR CAS NO: 39421-75-5

Hypromellose; 2-hydroxypropyl methyl ether Cellulose; Hydroxypropyl Methyl Cellulose CAS NO: 9004-65-3

guar gum, 2-hydroxypropyl 2-hydroxy-3-(trimethylammonio)propyl ether, chloride CAS NO:71329-50-5

N-(2-Hydroxyethyl)ethylenediamine-N,N′,N′-triacetic acid; N-Carboxymethyl-N′-(2-hydroxyethyl)-N,N′-ethylenediglycine, HEDTA, HEEDTA cas no: 150-39-0

HYDROXYPROPYL STARCH, N° CAS : 9049-76-7 / 68584-86-1, Nom INCI : HYDROXYPROPYL STARCH. Ses fonctions (INCI) :Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Noms français : (2-HYDROXYPROPOXY) STARCH;HYDROXYPROPYL STARCH;HYDROXYPROPYL-2, AMIDON;STARCH HYDROXYPROPYLATED;STARCH, 2-HYDROXYPROPYL ETHER.Utilisation et sources d'émission: Fabrication de papier, fabrication de colles ou adhésifs

HYDROXYPROPYL STARCH PHOSPHATE, N° CAS : 53124-00-8 / 39346-84-4 / 113894-92-1, Nom INCI : HYDROXYPROPYL STARCH PHOSPHATE. Ses fonctions (INCI) : Agent de foisonnement : Réduit la densité apparente des cosmétiques. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques

Guar Hydroxypropyltrimnonium Chlide; Guar hydroxypropyltrimonium chloride; Guar Hydroxypropyltiamonium Chloride; GUM GUAR 2-HYDROXY-3-(TRIMETHYLAMMONIO) cas no:65497-29-2

HYDROXYLAMINE; Hydroxylamine solution; HDA; hydroxylaminefree-base cas no : 7803-49-8

HYDROXYSTEARYL ALCOHOL, N° CAS : 2726-73-0, Nom INCI : HYDROXYSTEARYL ALCOHOL. Nom chimique : 1, 12-Ocatadecanediol. Classification : Alcool

HYDROXYPROPYLTRIMONIUM HYALURONATE; hyaluronic acid, 2-hydroxy-3-(N,N,N-trimethylammonio)propyl chloride derivatives CAS NO:9004-61-9

BHT, N° CAS : 128-37-0 - Hydroxytoluène butylé, Autre langue : Butil hidroxi tolueno (BHL), Nom INCI : BHT, Nom chimique : 2,6-Di-tert-butyl-p-cresol, N° EINECS/ELINCS : 204-881-4; Additif alimentaire : E321. Antioxydant : Inhibe les réactions favorisées par l'oxygène, évitant ainsi l'oxydation et la rancidité. Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Noms français :(DIMETHYLETHYL-1,1)BIS-2,6 METHYL-4 PHENOL; 2,6-BIS(1,1-DIMETHYLETHYL)-4-METHYL PHENOL; Hydroxy toluène butylé; Hydroxytoluène butylé (BHT) 2,6-BIS-(1,1-DIMETHYLETHYL)-4-METHYL PHENOL 2,6-DI-T-BUTYL-P-CRESOL 2,6-DI-TER-BUTYL-P-METHYLPHENOL 2,6-DI-TERT-BUTYL-1-HYDROXY-4-METHYLBENZENE 2,6-DI-TERT-BUTYL-4-METHYLPHENOL 2,6-Di-tert-butyl-p-cresol 2,6-DI-TERT-BUTYL-P-METHYLPHENOL 2,6-DI-TERT-BUTYL-PARA-CRESOL 2,6-DITERBUTYL-4-METHYLPHENOL 2,6-DITERTBUTYLCRESOL (PARA-) 3,5-DI-TERT-BUTYL-4-HYDROXYTOLUENE 4-HYDROXY-3,5-DI-TERT-BUTYLTOLUENE 4-METHYL-2,6-DI-TERT-BUTYLPHENOL Butyl hydroxy toluène Di-tert butyl hydroxytoluène DI-TERT-BUTYL-2,6 METHYL-4 PHENOL DI-TERT-BUTYL-2,6 P-CRESOL Di-tert-butyl-2,6 para-crésol DI-TERT-BUTYL-2,6 PARACRESOL DI-TERT-BUTYLCRESOL DI-TERTBUTYL HYDROXYTOLUENE DITERTBUTYL-2,6 CRESOL (PARA-) METHYLDI-TERT-BUTYLPHENOL O,O'-DI-TERT-BUTYL-P-CRESOL P-CRESOL, 2,6-DI-TERT-BUTYL- PHENOL, 2,6-BIS(1,1-DIMETHYLETHYL)-4-METHYL PHENOL, 2,6-BIS(1,1-DIMETHYLETHYL)-4-METHYL- Noms anglais : 2,6-Di-tert-butyl-p-cresol Butylated hydroxytoluene Butylated hydroxytoluene (BHT) DIBUTYLATED HYDROXYTOLUENE Utilisation et sources d'émission Agent anti-oxydant, agent de préservation alimentaire. 2,6-di-tert-Butyl-4-methylphenol 2,6-di-tert-butyl-p-cresol Butylated hydroxytoluene CAS names Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl- - 2,6-ditert-butyl-4-methylphenol 2,6 di-tert-butyl-p-cresol 2,6-(Di-t-butyl)-p-cresol 2,6-BIS(1,1-DIMETHYLETHYL)-4-METHYLPHENOL 2,6-di-t-Butyl-p-cresol 2,6-Di-tert-buthyl-4-methyphenol 2,6-di-tert-butil-para-cresol 2,6-Di-tert-butyl-4-hydroxytoluene 2,6-Di-tert-butyl-4-methyl-1-hydroxybenzene 2,6-di-tert-butyl-4-methylphenol; 2,6-DI-TERT-BUTYL-P-CRESOL(30435) 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, Butylhydroxytoluene, DBPC, Butylhydroxytoluenum 2,6-di-tert-butyl-p-cresol; BHT 2,6-di-tert-butyl-p-crezol 2,6-Di-tert-butyl-p-kresol 2,6-di-tert-butyl-p-krezol 2,6-di-tert-buytl-p-cresol 2,6-di-tert.-butyl-4-methylphenol 2,6-di-terz-butil-4-metilfenolo 2,6-ditert-butyl-4-methylphenol , 2,6-ditert-butyl-4-methylphenol. 4-methyl-2,6-di-(terc) butylfenol 4-methyl-2,6-di-tert-butyl-phenol BHT , Butil-hidroxi-toluol butylated hydroxytoluene, BHT Butylhydroxytoluol (BHT) Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl PHENOL,2,6-BIS(1,1-DIMETHYLETHYL)-4-METHYL- s 4-HYDROXY-3,5-DI-TERT-BUTYLTOLUENE 4-methyl-2,6-di-tert-butylphenol antioxidant premix (BHT) of technical grade Agidol 1 BHT of technical grade antioxidant premix, of A and B types BUTYLATED HYDROXY TOLUENE P-CRESOL, 2,6-DI-TERT-BUTYL- Technical grade (BHT). Butylated hydroxytoluene [BAN] [NF] [USAN] [Wiki] 128-37-0 [RN] 2,6-Di-t-butyl-4-hydroxytoluene 2,6-di-tert-butyl-4-methyl phenol 2,6-Di-tert-butyl-4-methylphenol 2,6-Di-tert-butyl-p-cresol 2,6-ジ-tert-ブチル-p-クレゾール [Japanese] 2,6-二叔丁基對甲酚 [Chinese] 246-911-9 [EINECS] 3,5-Di-tert-4-butylhydroxytoluene (BHT) 4-Methyl-2,6-bis(2-methyl-2-propanyl)phenol 4-Methyl-2,6-bis(2-methyl-2-propanyl)phenol [German] 4-Méthyl-2,6-bis(2-méthyl-2-propanyl)phénol [French] 4-Methyl-2,6-di-t-butyl-phenol 4-Methyl-2,6-ditertbutylphenol BHT BUTYLHYDROXYTOLUENE Butylhydroxytoluenum DBPC MFCD00011644 [MDL number] Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl- [ACD/Index Name] 1-Hydroxy-4-methyl-2,6-di-tert-butylbenzene 2,6-BIS(1,1-DIMETHYLETHYL)-4-METHYLPHENOL 2,6-bis(tert-butyl)-4-methylphenol 2,6-di-(tert.-butyl)-4-methylphenol 2,6-Di(tert-butyl)-4-methylphenol 2,6-Di-(tert-butyl)-4-methylphenol 2,6-Di(tert-butyl)hydroxytoluene 2,6-di-Butyl-para-cresol 2,6-Di-t-butyl-4-methylphenol 2,6-Di-t-butyl-p-cresol 2,6-di-ter-butyl-4-methyl-phenol 2,6-Di-terc.butyl-p-kresol [Czech] 2,6-Di-tert.-butyl-4-methylphenol 2,6-Di-tert-butyl-1-hydroxy-4-methyl benzene 2,6-Di-tert-butyl-1-hydroxy-4-methylbenzene 2,6-Di-tert-butyl-4-cresol 2,6-Di-tert-butyl-4-hydroxytoluene 2,6-Ditertbutyl-4-methyl phenol 2,6-di-tert-butyl-4-methylenol 2,6-Di-tert-butyl-4-methylhydroxybenzene 2,6-ditert-butyl-4-methyl-phenol 2,6-Di-tert-butyl-4-methyl-phenol 2,6-di-tert-butylcresol 2,6-di-tert-Butyl-methylphenol 2,6-Di-tert-butyl-para-methylphenol 2,6-Di-tert-butyl-p-methylphenol 3,5-DI-TERT-BUTYL-4-HYDROXYTOLUENE 4 Methyl 2,6 ditertbutylphenol 42615-30-5 secondary RN [RN] 4-cresol, 2,6-di-t-butyl- 4-Hydroxy-3,5-di-tert-butyltoluene 4-Methyl-2,6-di-terc. butylfenol [Czech] 4-methyl-2,6-ditert-butyl-phenol 4-Methyl-2,6-di-tert-butylphenol 4-Methyl-2,6-tert-butylphenol 50356-19-9 secondary RN [RN] 50641-99-1 secondary RN [RN] 52683-46-2 secondary RN [RN] 53571-70-3 secondary RN [RN] 58500-82-6 secondary RN [RN] 83047-16-9 secondary RN [RN] Advastab 401 Agidol Agidol 1 Alkofen BP Antioxidant 264 Antioxidant 29 Antioxidant 30 Antioxidant 4 Antioxidant 4K Antioxidant KB Antioxidant MPJ Antioxidant T 501 Antox QT Antracine 8 Antrancine 8 AO 4K AOX 4 AOX 4K BENZENE,1,3-DITERT.BUTYL,2-HYDROXY,5-METHYL Butyl hydroxy toluene Butylated hydroxytoluol Butylatedhydroxytoluene Butylhydroxytoluenum [Polish] Butylohydroksytoluenu [Polish] CAO 1 CAO 3 Catalin antioxydant 1 Catalin CAO-3 Chemanox 11 Dalpac DBMP Deenax Dibunol DIBUTYLATED HYDROXYTOLUENE Dibutylcresol Dibutylhydroxytoluene dibutylhydroxytoluene standard Dibutyl-para-cresol Dibutyl-p-cresol Di-tert-Butyl-4-methylphenol Di-tert-butylcresol Di-tert-Butylparamethylphenol di-tert-butyl-p-cresol Di-tert-butyl-p-cresol (VAN) Di-tert-butyl-p-methylphenol Embanox BHT Hydagen DEO Hydroxytoluene, Butylated Impruvol Ional Ionol Ionol (antioxidant) Ionol 1 Ionol CP Ionole Kerabit methyl di-tert-butyl phenol Methyldi-tert-butylphenol Nocrac 200 o-Di-tert-butyl-p-methylphenol Parabar 441 Paranox 441 p-Cresol, 2,6-di-tert-butyl- phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl Phenol, 2,6-di-tert-butyl-4-methyl- Phenol, 3,5-bis(1,1-dimethylethyl)-4-methyl- Popol Stavox SUSTANE Tenamen 3 Tenamene 3 TONAROL Topanol Topanol O Topanol OC Toxolan P Vanlube PC Vanlube PCX Vianol Vulkanox KBButylated hydroxytoluene [BAN] [NF] [USAN] [Wiki] 128-37-0 [RN] 1911640 [Beilstein] 2,6-Di-t-butyl-4-hydroxytoluene 2,6-di-tert-butyl-4-methyl phenol 2,6-Di-tert-butyl-4-methylphenol 2,6-Di-tert-butyl-p-cresol 2,6-ジ-tert-ブチル-p-クレゾール [Japanese] 2,6-二叔丁基對甲酚 [Chinese] 246-911-9 [EINECS] 3,5-Di-tert-4-butylhydroxytoluene (BHT) 4-Methyl-2,6-bis(2-methyl-2-propanyl)phenol 4-Methyl-2,6-bis(2-methyl-2-propanyl)phenol [German] 4-Méthyl-2,6-bis(2-méthyl-2-propanyl)phénol [French] 4-Methyl-2,6-di-t-butyl-phenol 4-Methyl-2,6-ditertbutylphenol BHT BUTYLHYDROXYTOLUENE Butylhydroxytoluenum DBPC MFCD00011644 [MDL number] Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl- [ACD/Index Name] 1-Hydroxy-4-methyl-2,6-di-tert-butylbenzene 2,6-BIS(1,1-DIMETHYLETHYL)-4-METHYLPHENOL 2,6-bis(tert-butyl)-4-methylphenol 2,6-di-(tert.-butyl)-4-methylphenol 2,6-Di(tert-butyl)-4-methylphenol 2,6-Di-(tert-butyl)-4-methylphenol 2,6-Di(tert-butyl)hydroxytoluene 2,6-di-Butyl-para-cresol 2,6-Di-t-butyl-4-methylphenol 2,6-Di-t-butyl-p-cresol 2,6-di-ter-butyl-4-methyl-phenol 2,6-Di-terc.butyl-p-kresol [Czech] 2,6-Di-tert.-butyl-4-methylphenol 2,6-Di-tert-butyl-1-hydroxy-4-methyl benzene 2,6-Di-tert-butyl-1-hydroxy-4-methylbenzene 2,6-Di-tert-butyl-4-cresol 2,6-Di-tert-butyl-4-hydroxytoluene 2,6-Ditertbutyl-4-methyl phenol 2,6-di-tert-butyl-4-methylenol 2,6-Di-tert-butyl-4-methylhydroxybenzene 2,6-ditert-butyl-4-methyl-phenol 2,6-Di-tert-butyl-4-methyl-phenol 2,6-di-tert-butylcresol 2,6-di-tert-Butyl-methylphenol 2,6-Di-tert-butyl-para-methylphenol 2,6-Di-tert-butyl-p-methylphenol 3,5-DI-TERT-BUTYL-4-HYDROXYTOLUENE 4 Methyl 2,6 ditertbutylphenol 42615-30-5 secondary RN [RN] 4-cresol, 2,6-di-t-butyl- 4-Hydroxy-3,5-di-tert-butyltoluene 4-Methyl-2,6-di-terc. butylfenol [Czech] 4-methyl-2,6-ditert-butyl-phenol 4-Methyl-2,6-di-tert-butylphenol 4-Methyl-2,6-tert-butylphenol 50356-19-9 secondary RN [RN] 50641-99-1 secondary RN [RN] 52683-46-2 secondary RN [RN] 53571-70-3 secondary RN [RN] 58500-82-6 secondary RN [RN] 83047-16-9 secondary RN [RN] Advastab 401 Agidol Agidol 1 Alkofen BP Antioxidant 264 Antioxidant 29 Antioxidant 30 Antioxidant 4 Antioxidant 4K Antioxidant KB Antioxidant MPJ Antioxidant T 501 Antox QT Antracine 8 Antrancine 8 AO 4K AOX 4 AOX 4K BENZENE,1,3-DITERT.BUTYL,2-HYDROXY,5-METHYL Butyl hydroxy toluene Butylated hydroxytoluol Butylatedhydroxytoluene Butylhydroxytoluenum [Polish] Butylohydroksytoluenu [Polish] CAO 1 CAO 3 Catalin antioxydant 1 Catalin CAO-3 Chemanox 11 Dalpac DBMP Deenax Dibunol DIBUTYLATED HYDROXYTOLUENE Dibutylcresol Dibutylhydroxytoluene dibutylhydroxytoluene standard Dibutyl-para-cresol Dibutyl-p-cresol Di-tert-Butyl-4-methylphenol Di-tert-butylcresol Di-tert-Butylparamethylphenol di-tert-butyl-p-cresol Di-tert-butyl-p-cresol (VAN) Di-tert-butyl-p-methylphenol Embanox BHT Hydagen DEO Hydroxytoluene, Butylated Impruvol Ional Ionol Ionol (antioxidant) Ionol 1 Ionol CP Ionole Kerabit methyl di-tert-butyl phenol Methyldi-tert-butylphenol Nocrac 200 o-Di-tert-butyl-p-methylphenol Parabar 441 Paranox 441 p-Cresol, 2,6-di-tert-butyl- phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl Phenol, 2,6-di-tert-butyl-4-methyl- Phenol, 3,5-bis(1,1-dimethylethyl)-4-methyl- Popol Stavox SUSTANE Tenamen 3 Tenamene 3 TONAROL Topanol Topanol O Topanol OC Toxolan P Vanlube PC Vanlube PCX Vianol Vulkanox KB

SODIUM HYPOCHLORITE, N° CAS : 7681-52-9 - Hypochlorite de sodium (Eau de javel), Origine(s) : Synthétique, Nom INCI : SODIUM HYPOCHLORITE. Nom chimique : Hypochlorous Acid, Sodium Salt. N° EINECS/ELINCS : 231-668-3. L'hypochlorite de sodium est un composé chimique souvent utilisé en solution aqueuse en tant que désinfectant et agent de blanchiment. Il entre dans la composition de l'eau de javel.Ses fonctions (INCI): Agent Oxydant : Modifie la nature chimique d'une autre substance en ajoutant de l'oxygène ou en éliminant l'hydrogène

hylocereus undatus extract; extract of the whole plant, hylocereus undatus, cactaceae; honolulu-queen extract; queen-of-the-night extract; dragon fruit extract CAS NO:999999-999-4

extract of the fruit of hylocereus undatus, cactaceae; dragon fruit extract; dragon fruit extract natural; Pitaya (Drafon fruit) Extract; Propylene Glycol (and) Water (and) Sorbitol (and) Hylocereus Undatus Fruit Extract (and) Ascorbic Acid;Tomato Fruit extract CAS NO:999999-99-4

saint johns wort; Powdered St. John's Wort Extract; Hypericum perforatum extract, St. John´s wort extract CAS NO:84082-80-4

HYPOCHLOROUS ACID, N° CAS : 7790-92-3, Nom INCI : HYPOCHLOROUS ACID. Nom chimique : Hypochlorous Acid. N° EINECS/ELINCS : 239-555-0 (I) Ses fonctions (INCI) Anti-séborrhée : Aide à contrôler la production de sébum Déodorant : Réduit ou masque les odeurs corporelles désagréables Agent Oxydant : Modifie la nature chimique d'une autre substance en ajoutant de l'oxygène ou en éliminant l'hydrogène

HYPOCHLOROUS ACID, N° CAS : 7790-92-3. Nom INCI : HYPOCHLOROUS ACID, Nom chimique : Hypochlorous Acid, N° EINECS/ELINCS : 239-555-0 (I). Ses fonctions (INCI) : Anti-séborrhée : Aide à contrôler la production de sébum. Déodorant : Réduit ou masque les odeurs corporelles désagréables. Agent Oxydant : Modifie la nature chimique d'une autre substance en ajoutant de l'oxygène ou en éliminant l'hydrogène

Hypophosphorous acid; Phosphinic Acid; Acide phosphinique; Phosphinsäure; ácido fosfínico; cas no: 6303-21-5

IMBENTIN PPF; POE/POP adduct cas no: 69013-18-9

2-(4-isobutylphenyl)propionic Acid; Apsifen; Apsifen-F; Alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid; Acide (Isobutyl-4 Phenyl)-2 Propionique (French); Ibuprocin; para-Isobutylhydratropic acid; (+/-)-2-(p-Isobutyl phenyl)propionic acid; (+)-2-(4-Isobutyl phenyl)propionic acid; 4-Isobutyl- alpha-methylphenylacetic acid; Ibufen; Ibuprin; Alpha-methyl-4-(2-Methylpropyl)- Benzeneacetic Acid; cas no: 15687-27-1

ice tea lemon flavor

Ammonii bituminosulfonat; Ammonium bithiolicum;Ammonium ichthosulfonate;Ammonium sulfobituminosumAmmonium sulfoichthyolate;Ammoniumbituminosulfonat;Ammoniumbituminosulfonate DAB;Amsubit; CAS NO:8029-68-3

Ichthammol; Ammonium bituminosulfonate; ıchthyol; karayağ; blackoil; CAS NO : 8029-68-3

IDACOL ACID RED 33 IUPAC Name disodium;5-amino-4-hydroxy-3-phenyldiazenylnaphthalene-2,7-disulfonate IDACOL ACID RED 33 InChI InChI=1S/C16H13N3O7S2.2Na/c17-12-8-11(27(21,22)23)6-9-7-13(28(24,25)26)15(16(20)14(9)12)19-18-10-4-2-1-3-5-10;;/h1-8,20H,17H2,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2 IDACOL ACID RED 33 InChI Key LQJVOKWHGUAUHK-UHFFFAOYSA-L IDACOL ACID RED 33 Canonical SMILES C1=CC=C(C=C1)N=NC2=C(C3=C(C=C(C=C3C=C2S(=O)(=O)[O-])S(=O)(=O)[O-])N)O.[Na+].[Na+] IDACOL ACID RED 33 Molecular Formula C16H11N3Na2O7S2 IDACOL ACID RED 33 CAS 3567-66-6 IDACOL ACID RED 33 Deprecated CAS 64553-75-9 IDACOL ACID RED 33 European Community (EC) Number 222-656-9 IDACOL ACID RED 33 UNII 9DBA0SBB0L IDACOL ACID RED 33 DSSTox Substance ID DTXSID1044562 IDACOL ACID RED 33 Food Additive Classes Food Additives -> COLOUR IDACOL ACID RED 33 Molecular Weight 467.4 g/mol IDACOL ACID RED 33 Hydrogen Bond Donor Count 2 IDACOL ACID RED 33 Hydrogen Bond Acceptor Count 10 IDACOL ACID RED 33 Rotatable Bond Count 2 IDACOL ACID RED 33 Exact Mass 466.983381 g/mol IDACOL ACID RED 33 Monoisotopic Mass 466.983381 g/mol IDACOL ACID RED 33 Topological Polar Surface Area 202 Ų IDACOL ACID RED 33 Heavy Atom Count 30 IDACOL ACID RED 33 Formal Charge 0 IDACOL ACID RED 33 Complexity 757 IDACOL ACID RED 33 Isotope Atom Count 0 IDACOL ACID RED 33 Defined Atom Stereocenter Count 0 IDACOL ACID RED 33 Undefined Atom Stereocenter Count 0 IDACOL ACID RED 33 Defined Bond Stereocenter Count 0 IDACOL ACID RED 33 Undefined Bond Stereocenter Count 0 IDACOL ACID RED 33 Covalently-Bonded Unit Count 3 IDACOL ACID RED 33 Compound Is Canonicalized Yes IDACOL ACID RED 33 Applications: Cosmetics Pharmaceuticals Soaps - Cold Process and Melt and Pour D&C Red 33 also known as IDACOL ACID RED 33 or simply Red 33 is a red azo dye used as a colorant in mouthwashes, dentifrices, cosmetics, and hair dyes.[1] IDACOL ACID RED 33 is a disodium salt of 5-amino-4-hydroxy-3-(phenylazo)-2,7-naphthalenedisulfonic acid, which can be purified through high performance liquid chromatography.IDACOL ACID RED 33 is a red dye used as a colorant in cosmetic products.The electrochemical oxidation (EO) performance of prepared electrode was investigated using IDACOL ACID RED 33 (AR33) as a model pollutant.IDACOL ACID RED 33 4.FD.033000 is an FDA and global approved, high purity water soluble powder dye. Main applications are make-up, sun care, skin care and toiletries products.The color additive IDACOL ACID RED 33 may be safely used for coloring ingested drugs in amounts not to exceed 0.75 milligram per daily dose of the drug. IDACOL ACID RED 33 may be safely used for coloring externally applied drugs, mouthwashes, and dentifrices in amounts consistent with current good manufacturing practice. IDACOL ACID RED 33 may also be safely used for coloring cosmetic lip products in amounts not to exceed 3 percent total color by weight of the finished cosmetic products. IDACOL ACID RED 33 may be safely used for coloring mouthwashes (including breath fresheners), dentifrices, and externally applied cosmetics in amounts consistent with current good manufacturing practice.IDACOL ACID RED 33 is a drug and cosmetic synthetic dye. The FDA lists it as a safe additive for drugs and cosmetics as per FDA standards. In cosmetics, it can be used externally and in general cosmetics, including lipsticks, but is not to be used in cosmetics close to the eye.IDACOL ACID RED 33 (D&C Red No. 33) and IDACOL ACID RED 33 are synthetic colorants. In cosmetics and personal care products, IDACOL ACID RED 33 and IDACOL ACID RED 33 Lake are used in the formulation of a wide variety of product types, including makeup and lipstick.IDACOL ACID RED 33 is used to impart a red color to cosmetics and personal care products.The color additive IDACOL ACID RED 33 is principally the disodium salt of 5-amino-4-hydroxy-3-(phenylazo)-2,7-naphthalenedisulfonic acid (CAS Reg. No. 3567-66-6). To manufacture the additive, the product obtained from the nitrous acid diazotization of aniline is coupled with 4-hydroxy-5-amino-2,7-naphthalenedisulfonic acid in an alkaline aqueous medium. The color additive is isolated as the sodium salt.Color additive mixtures for drug use made with IDACOL ACID RED 33 may contain only those diluents that are suitable and that are listed in part 73 of this chapter as safe for use in color additive mixtures for coloring drugs.Specifications. IDACOL ACID RED 33 shall conform to the following specifications and shall be free from impurities other than those named to the extent that such impurities may be avoided by current good manufacturing practices:Sum of volatile matter at 135 deg. C (275 deg. F) and chlorides and sulfates (calculated as sodium salts), not more than 18 percent.Uses and restrictions. The color additive IDACOL ACID RED 33 may be safely used for coloring ingested drugs, other than mouthwashes and dentifrices, in amounts not to exceed 0.75 milligram per daily dose of the drug. d&c red no. 33 may be safely used for coloring externally applied drugs, mouthwashes, and dentifrices in amounts consistent with current good manufacturing practice.All batches of IDACOL ACID RED 33 shall be certified in accordance with regulations in part 80 of this chapter.IDACOL ACID RED 33 is used frequently to obtain those amazing colors in bath bombs and bubble products due to the fact that it will color the water but not skin or the tub unless used in large quantity.There is currently a conflict of opinion and clarity on the FDA website as to the use of IDACOL ACID RED 33 in bath bombs.IDACOL ACID RED 33 is a colorant, or dye. We add dyes to products for a variety of reasons including helping you see where you applied the product, when a product is used up, or for aesthetic reasons. This dye is available from multiple suppliers, which are responsible for its contents.Liquid IDACOL ACID RED 33 is a pre-mixed water based liquid dye. Great for soaps, bath salts, bath bombs, body powders, and other water based or dry formulations. Add to your water phase drop by drop until you get the desired color.FNWL uses the standardized name for this color additive. Standardized names, however, can sometimes be vague. In our experience, IDACOL ACID RED 33 is a deep shade of red with a slightly pinkish-violet tint. The amount of colorant that you use will affect the intensity and vibrancy of the hue.The test of photocatalytic activities of the heat-treated TiO2 powders were carried out through the photocatalytic degradation of IDACOL ACID RED 33 dye in aqueous solution under the irradiation of visible light.The results indicate that the TiO2 photocatalyst heat-treated at 400 °C within 60 min shows the highest photocatalytic activity which can effectively degrade the IDACOL ACID RED 33 under the irradiation of visible light. The total degradation process of IDACOL ACID RED 33 has been monitored by UV–vis spectra and ion chromatography. At last, the IDACOL ACID RED 33 molecules in aqueous solution are completely degraded and become some simple inorganic ions such as NO3− and SO42−, etc.UV–Vis spectra of IDACOL ACID RED 33 solutions under different conditions (10 mg/L IDACOL ACID RED 33 concentration, 1.0 g/L Er3+:Y3Al5O12/TiO2–ZrO2 (with Ti/Zr = 7:3 molar ratio), Er3+:Y3Al5O12/TiO2 or Er3+:Y3Al5O12/ZrO2 (with 10 wt% Er3+:Y3Al5O12 at 500 °C for 50 min heat treatment) catalyst amount, 100 mL total volume and 60 min solar light irradiation. (a) IDACOL ACID RED 33 dye solution without any catalyst in the dark (original solution); (b) IDACOL ACID RED 33 dye solution without any catalyst under solar light irradiation; (c) IDACOL ACID RED 33 dye solution with Er3+:Y3Al5O12/ZrO2 composite in the dark; (d) IDACOL ACID RED 33 dye solution with Er3+:Y3Al5O12/TiO2–ZrO2 composite in the dark; (e) IDACOL ACID RED 33 dye solution with Er3+:Y3Al5O12/TiO2 composite in the dark; (f) IDACOL ACID RED 33 dye solution with Er3+:Y3Al5O12/ZrO2 composite under solar light irradiation; (g) IDACOL ACID RED 33 dye solution with TiO2 powder under solar light irradiation; (h) IDACOL ACID RED 33 dye solution with Er3+:Y3Al5O12/TiO2 composite under solar light irradiation; (i) IDACOL ACID RED 33 dye solution with Er3+:Y3Al5O12/TiO2–ZrO2 composite under solar light irradiation)

linden flavor

Citrus aurantifolia extract ;citrus aurantifolia swingle flower extract; lime flower extract; sour lime flower extract; extract of the flowers of the lime, citrus aurantifolia, rutaceae cas no:90063-52-8

ilex paraguariensis leaf extract; yerba mate leaf extract; extract of the leaves of the paraguay tea, ilex paraguariensis, aquifoliaceae CAS NO:97676-25-0

SynonymsE132;Was35;l-blau2;murabba;CI 73015;1311blue;Greell S;12070blue;acidbluew;c.i.75781 CAS No.860-22-0

imidazolidinyl urea; imidurea; urea, N,N''-methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]- CAS NO: 39236-46-9

IMWITOR 960 K IMWITOR 960 K Personal Care & Cosmetics IMWITOR 960 K is a classic emulsifier for rich creams and butters. Works best at neutral pH. This self-emulsifying glyceryl stearate quality contains a monoester content of approx. 30%. Glyceryl stearate SE/Mono- and diglycerides based on edible fats. Solubilizing agent for actives. Bacteriostatic. Penetration enhancing. Emulsions Oil in Water Claims Emulsifiers > Emulsifiers O/W (Oil in Water) Solubilizers Appearance Flakes Product Status COMMERCIAL Product information INGREDIENT IDENTIFICATION Name IMWITOR® 960 K Segment Personal care INCI name Glyceryl Stearate SE An oily kind of ingredient that can magically blend with water all by itself. This is called self-emulsifying and SE in its name stands for that. The difference between "normal" Glyceryl Stearate and this guy is that the SE grade contains a small amount of water-loving soap molecules, such as sodium stearate. This increases Glyceryl Stearate's affinity for water and gives it stronger emulsifying abilities. What Is It? Glyceryl Stearate and Glyceryl Stearate SE are esterification products of glycerin and stearic acid. Glyceryl Stearate is a white or cream-colored wax-like solid. IMWITOR 960 K is a "Self-Emulsifying" form of Glyceryl Stearate that also contains a small amount of sodium and or potassium stearate. In cosmetics and personal care products, Glyceryl Stearate is widely used and can be found in lotions, creams, powders, skin cleansing products, makeup bases and foundations, mascara, eye shadow, eyeliner, hair conditioners and rinses, and suntan and sunscreen products. Why is it used in cosmetics and personal care products? Glyceryl Stearate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also slows the loss of water from the skin by forming a barrier on the skin's surface. Glyceryl Stearate, and Glyceryl Stearate SE help to form emulsions by reducing the surface tension of the substances to be emulsified. Scientific Facts: Glyceryl Stearate is made by reacting glycerin with stearic acid, a fatty acid obtained from animal and vegetable fats and oils. IMWITOR 960 K is produced by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide yielding a product that contains Glyceryl Stearate as well as potassium stearate and/or sodium stearate. Oil-Soluble, Self-Emulsifying Water-in-Oil Emulsifier IMWITOR 960 K is classified as : Emulsifying CAS Number 11099-07-3 EINECS/ELINCS No: 234-325-6 COSING REF No: 76256 Chem/IUPAC Name: Octadecanoic acid, reaction products with 1,2,3-propanetriol (1:1), neutralized WHAT IS GLYCERYL STEARATE? Glyceryl Stearate, also referred to as Glyceryl Monostearate, is a fatty acid derived from vegetable oil, Soy Oil, or Palm Kernel Oil; however, it is also naturally occurring in the human body. This wax-like substance appears white or cream in color and is produced when Glycerin and Stearic Acid undergo esterification. Traditionally, it is used in formulations for its emulsifying properties. Glyceryl Stearate SE also contains Sodium Stearate and/or Potassium Stearate. The “SE” of Glyceryl Stearate SE stands for “Self-Emulsifying,” as it is a self-emulsifying form of Glyceryl Stearate. HOW DOES GLYCERYL STEARATE WORK? When applied topically, its Glycerol constituent makes Glyceryl Stearate SE a fast-penetrating emollient that helps to create a protective barrier on the surface of the skin. This helps retain hydration and slow the loss of moisture. This reduced rate of water evaporation helps to lubricate, condition, soften, and smoothe the skin. Its protective properties extend to its antioxidant qualities, which help protect the skin against damage caused by free radicals. When added to natural formulations, Glyceryl Stearate and Glyceryl Stearate SE have stabilizing effects on the final product, which means it helps the other ingredients in the formulation to continue functioning effectively in order to go on exhibiting their beneficial properties. In this way, it helps to balance the product’s pH value and thereby prevents the product from becoming overly acidic or alkaline. Furthermore, it helps increase shelf life, prevents products from freezing or from developing crusts on their surfaces, and it helps lessen the greasy nature of some oils that may be added to cosmetics formulations. In formulations that are oil-based, the thickening properties of Glyceryl Stearate SE help to scale down the need for co-emulsifiers and, in emulsions with big water phases, Glyceryl Stearate SE can help develop liquid crystal phases as well as crystalline gel phases. As an opacifier, it makes transparent or translucent preparations opaque, thus protecting them from or increasing their resistance to being penetrated by visible light. This also helps to boost or balance the appearance of pigments and to improve the density of the final product for a luxuriously smooth and creamy texture. APPLICATIONS FOR GLYCERYL STEARATE SEIMWITOR 960 K must be added to formulations in their heated oil phases. The higher the concentration of Glyceryl Stearate SE, the thicker the end product will be. PRODUCT TYPE & FUNCTION EFFECTS When added to this kind of formulation… Shampoo/Conditioner IMWITOR 960 K functions as a(n): Moisturizer Opacifier Softener Conditioner Thickener It helps to: Hydrate the hair and scalp to protect against dryness Prevent frizz Make products opaque in appearance Increase viscosity Reduce tangling The recommended maximum dosage is 2-5% When added to these kinds of formulations… Makeup (Foundation, Mascara, Eye Shadow, Eyeliner) IMWITOR 960 K functions as a(n): Opacifier Softener Emollient It helps to: Soften and smoothe the skin Balance and sustain the skin's moisture levels without leaving a greasy residue Keep makeup on the skin, rather than allowing it to fall off Keep mascara from clumping Ensure smooth application of eyeliner and eyeshadow The recommended maximum dosage is 2-5% When added to these kinds of formulations… Moisturizer Face Wash Face Mask/Peel Body Wash/Gel IMWITOR 960 K functions as a(n): Opacifier Thickener Co-emulsifier Emollient Softener Moisturizer Cleanser It helps to: Emulsify formulations and increase their viscosity, which contributes a creamier texture Lift and remove dirt Soothe skin Create an oily layer on the skin’s surface, which helps it retain water Hydrate and soften the skin to reduce irritation, cracking, and peeling Recommended maximum dosages are: Body Lotion: 1.5-2.5% Face Cream: 1.5-2.5% Sunscreen: 1.5-2.5% Ointments: 2-5% CONTRAINDICATIONS FOR GLYCERYL STEARATE As with all other New Directions Aromatics products, Glyceryl Stearate SE Raw Material is for external use only. It is imperative to consult a medical practitioner before using this wax for therapeutic purposes. Pregnant and nursing women, as well as those with sensitive skin, are especially advised not to use Glyceryl Stearate SE Raw Material without the medical advice of a physician. This product should always be stored in an area that is inaccessible to children, especially those under the age of 7. Prior to using Glyceryl Stearate SE Raw Material, a skin test is recommended. This can be done by melting 1 Glyceryl Stearate wax flake in 1 ml of a preferred Carrier Oil and applying a dime-size amount of this blend to a small area of skin that is not sensitive. Potential side effects of Glyceryl Stearate SE include irritation, rash, stinging, burning, nausea, flatulence, abdominal cramps, and diarrhea. In the event of an allergic reaction, discontinue use of the product and see a doctor, pharmacist, or allergist immediately for a health assessment and appropriate remedial action. To prevent side effects, consult with a medical professional prior to use. Molecular Weight 1704.7 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Hydrogen Bond Donor Count 6 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Hydrogen Bond Acceptor Count 16 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Rotatable Bond Count 90 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Exact Mass 1704.409171 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Monoisotopic Mass 1703.405816 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Topological Polar Surface Area 281 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Heavy Atom Count 117 Computed by PubChem Formal Charge 0 Computed by PubChem Complexity 754 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Isotope Atom Count 0 Computed by PubChem Defined Atom Stereocenter Count 2 Computed by PubChem Undefined Atom Stereocenter Count 0 Computed by PubChem Defined Bond Stereocenter Count 0 Computed by PubChem Undefined Bond Stereocenter Count 0 Computed by PubChem Covalently-Bonded Unit Count 7 Computed by PubChem Compound Is Canonicalized Yes

Acid Blue 74, Indigo-5,5′-disulfonic acid disodium salt, Indigocarmine cas no: 860-22-0

IPBC; 3-Iodo-2-propynyl N-butylcarbamate; Troysan; 3-Iodo-2-propynyl butylcarbamate; 3-IODO-2-PROPYNYL BUTYLCARBAMATE; 3-IODO-2-PROPYNYL N-BUTYLCARBAMATE; 3-Iodopropynyl butylcarbamate; asc 67000; IBP; IODOCARB; IODOPROPYNYL BUTYLCARBAMATE; Kitazine P; o,o-bis(1-methylethyl) s-(phenylmethyl) phosphorothioate; PERMATOX; TROYSAN POLYPHASE 588; 3-iodo-2-propynyl; butyl-carbamicaci3-iodo-2-propynylester; Carbamicacid,butyl-,3-iodo-2-propynylester; ipbc(3-iodo-2-propynylnbutylcarbamate); troysankk-108a; troysanpolyphaseanti-mildew; woodlife; Butylcarbamic acid 3-iodo-2-propynyl ester CAS NO: 55406-53-6

Indigo Blue; Indigotin; C.I. Vat Blue 1; C.I. 73000; C.I. Pigment Blue 66; [delta(2,2')-Biindoline]-3,3'-dione; delta(2,2')Bipseudoindoxyl; 2-(1,3-Dihydro-3-oxo-2H-indol- 2-ylidene)-1, 2-dihydro -3H-indol-3-one; 2,2'-Bi(2,3-dihydro-3-oxoindolylidene); 2;2,3,2',3'-Tetrahydro-3,3'-dioxo-2,2'- biindolylidene; 2,3,2',3'-Tetrahydro-3,3'-dioxo-2,2'- biindolylidene; cas no: 482-89-3

ARNICA INFUSED; Arnica flower (Arnica montana) infused ; ARNICA, INFUSED IN SUNFLOWER OIL; ARNICA MONTANA CAS NO: 68990-11-4

COMFREY OIL INFUSED; Comfrey Oil Infused; Symphytum Officinale Leaf Extract; Symphytum officinale; comfrey seed oil CAS NO: 84696-05-9

SYNONYMS Lactose; (+)-Lactose; Lactose anhydrous; Milk sugar; 4-(beta-D-Galactosido)-D-glucose; 4-O-beta-D-Galactopyranosyl-D-glucose; Aletobiose; D-Lactose; 1-beta-D-Galactopyranosyl-4-D-glucopyranose; Lactobiose; Lactosum anhydricum; beta-D-galactopyranosyl-(1->4)-D-glucopyranose; (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6- ((2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl) oxyoxane-3,4,5-triol; CAS NO:63-42-3 (anhydrous), 64044-51-5 (hydrate)

Inositol; Meat sugar; meso-Inositol; Dambose; Cyclohexanehexol; Hexahydrocyclohexane; 1,2,3,4,5,6-hexahydroxycyclohexane; Inosital; Inositene; Inositina; Insitolum; Mesoinosite; Mesoinositol; Phaseomannite; Phaseomannitol; i-Inositol; Other RN: 53319-35-0 cas no: 87-89-8

inula helenium root extract; extract of the roots of the elecampane, inula helenium l., compositae; elecampace P.E.; elecampane root extract CAS NO:84012-20-4

IPBC, IODOPROPYNYL BUTYLCARBAMATE; 3-Iodo-2-propyn-1-yl butylcarbamate; N° CAS : 55406-53-6 - Butylcarbamate d'iodopropynyle (IPBC). Nom INCI : IODOPROPYNYL BUTYLCARBAMATE, Nom chimique : 3-Iodo-2-propynyl butylcarbamate, N° EINECS/ELINCS : 259-627-5. Classification : Règlementé, Conservateur, Ses fonctions (INCI). Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétiques.Noms français : Butylcarbamate d'iodo-3 propynyl-2; Butylcarbamate d'iodopropynyle. Noms anglais : 3-IODO-2-PROPYNYL BUTYLCARBAMATE; CARBAMIC ACID, BUTYL-, 3-IODO-2-PROPYNYL ESTER; Iodopropynyl butylcarbamate. Utilisation et sources d'émission :Fongicide et agent antimicrobien utilisé dans les procédés industriels et les constructions résidentielles. 259-627-5 [EINECS]; 3-Iod-2-propin-1-yl-butylcarbamat [German] [ACD/IUPAC Name]; 3-Iod-2-propin-1-yl-hydrogenbutylkohlenstoffimidat [German] [ACD/IUPAC Name]; 3-Iodo-2-propyn-1-yl butylcarbamate [ACD/IUPAC Name]; 3-Iodo-2-propyn-1-yl hydrogen butylcarbonimidate [ACD/IUPAC Name]; 3-Iodo-2-propynyl butylcarbamate ;3-Iodo-2-propynyl N-butylcarbamate; 3-iodo-2-propynyl-butylcarbamate; 3-Iodo-2-propynylbutylcarbamate3-Iodo-2-propynyl-N-butylcarbamate; 55406-53-6 [RN]; Butylcarbamate de 3-iodo-2-propyn-1-yle [French] [ACD/IUPAC Name]; Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester [ACD/Index Name]; EZ0950000; Hydrogénobutylcarbonimidate de 3-iodo-2-propyn-1-yle [French] [ACD/IUPAC Name]; I1UU2OVM4 [WLN]; Iodocarb; Iodopropynyl butylcarbamate ; Ipbc; Methanol, 1-(butylimino)-1-[(3-iodo-2-propyn-1-yl)oxy]-, (Z)- [ACD/Index Name];MFCD00072438 [MDL number]; ipbc; [55406-53-6]; 1-Iodoprop-1-yn-3-yl N-n-butylcarbamate; 3-iodo-2-propyn-1-yl N-butylcarbamate; 3-iodo-2-propynyi butylcarbamate; 3-Iodo-2-propynyl butyl carbamic acid 3-iodo-2-propynyl n-butylcarbamate; 3-iodo-2-propynyl??n-butylcarbamate; 3-Iodo-2-propynylbutyl carbamate; 3-iodoprop-2-yn-1-yl N-butylcarbamate; 3-iodoprop-2-ynyl butylcarbamate 3-iodoprop-2-ynyl N-butylcarbamate; 3-Iodopropynyl butylcarbamate; 3-IPBC; '55406-53-6; Butyl-3-iodo-2-propynylcarbamate; C106572; Carbamic acid, butyl-, 3-iodo-2-propynyl ester; carbamic acid, butyl-, 3-iodoprop-2-ynyl ester; Carbamic acid, butyl-3-iodo-2-propynyl ester; EINECS 259-627-5; Iodocarb (IPBC); iodocarbe; iodopropynyl??butylcarbamate; Iodopropynylbutylcarbamate , N-[2-(1-iodoethyl)pent-3-enyl]carbamate;N-butyl(3-iodoprop-2-ynyloxy)carboxamide; N-butylcarbamic acid 3-iodoprop-2-ynyl ester; NCGC00164376-01; OR-0600; Troysan KK-108A; Troysan KK-108A; Troysan polyphase anti-mildew; Woodlife; Troysan polyphase anti-mildew; Woodlife

IONOL CP представляет собой белый кристаллический антиоксидант и относится к группе не окрашивающих, стерически затрудненных фенолов.
IONOL CP - это пищевой антиоксидант, отвечающий большинству требований по охране труда и технике безопасности, включая требования FDA, а IONOL CP производится в соответствии с принципами HACCP для обеспечения безопасности пищевых продуктов.
Кроме того, IONOL CP соответствует аналитическим требованиям FCC (Food Chemical Codex) и фармакопеи EurPh и USP.

Номер CAS: 128-37-0
Номер ЕС: 204-881-4
Молекулярная формула: C15H24O
Молекулярный вес: 220,4 г/моль

IONOL CP также известен как бутилированный гидрокситолуол (BHT).
IONOL CP - это высококачественный антиоксидант с типичной чистотой 99,8%.

IONOL CP представляет собой 2,6-дитерт-бутил (1,1-диметилэтил)-4-метилфенол.
СодержаниеC15H240 должно составлять не менее 98,5% в пересчете на безводный.

IONOL CP, IONOL 220, IONOL 103 и IONOL 99 являются высокоэффективными антиоксидантами для всесезонных смазок, жидкостей для автоматических трансмиссий, дифференциальных жидкостей и турбинных масел.

Крометого, доказано, что ионные антиоксиданты увеличивают срок службы многих промышленных масел, сокращая время простоя оборудования.
Области применения включают гидравлические жидкости, трансформаторные масла, прядильные масла, а также жидкости для прокатки металла и смазочно-охлаждающие жидкости.

Антиоксиданты IONOL являются отличными стабилизаторами для всех марок реактивного топлива А1 на основе керосина для гражданского и военного применения.
Концентрация, необходимая для защиты и стабилизации авиационного топлива, также определяется этими международными спецификациями.
Например, DERD 2494 определяет добавочныйуровень в диапазоне 17,0 – 24,0 мг/л для гидроочищенных топлив.

Области применения IONOL CP:

Полимеры:
IONOL CP используется для стабилизации пластмасс, натурального и синтетического каучука, восков, синтетических и натуральных смол, а также для изделий и смесей, которые производятся из любого из вышеперечисленных компонентов.
Стабилизация с помощью IONOL CP начинается с производства пластмасс и обеспечивает, в зависимости от количества дозировки, стабильность полимерного сырья при хранении до переработки в готовое изделие.

Во время переработки полимерного сырья в конечный продукт дополнительная долговременная стабилизация с помощью IONOL CP может быть очень эффективной.
Область применения IONOL CP широко распространена благодаря превосходному соотношению затрат и эффективности, а такжепрактически универсальным возможностям применения IONOL CP в пластмассах, особенно для изделий, требующих одобрения в соответствии с законодательством о контакте с пищевыми продуктами.

Клеи и горячие расплавы:
Клеи и горячие расплавы также подвержены самоокислительному повреждению, вызванному механическимстрессом, высокой температурой и светом.
IONOL CP используется как для процесса, так и для долговременной стабилизации.

Пахучие вещества:
В пахучих веществах, например, в средствах по уходу за телом, IONOL CP предотвращает процессы самоокисления, которые приводят к образованию нежелательных и неприятно пахнущих продуктов разложения.

Продукты питания:
В пищевых продуктах IONOL CP замедляет разрушительное действие жиров, каротиноидов, витаминов, а также других основных компонентов пищи, вызванных окислением атмосферным кислородом.

Полиолы:
Полиолыподвержены окислительным повреждениям под действием света и тепла в присутствии кислорода из-за радикальных реакций.
При использовании IONOL CP реакционноспособные радикалы захватываются и превращаются в нереактивные соединения.

Цепная реакция остановлена, и можно избежать дальнейшего ущерба.
IONOL CP используется в качестве долговременного стабилизатора для защиты полиолов во время хранения (например, перед использованием в полиуретанах) от реакций разложения.
В зависимости от применения оптимальная дозировка составляет 0,1 - 1,0%.

Дальнейшие примененияIONOL CP:

Полиуретаны:
IONOL CP используется для полиуретанов в качестве обрабатывающего и долговременного стабилизатора.
В частности, при производстве пенополиуретанов IONOL CP более эффективен, чем многие другие антиоксиданты.

Из-за высокихтемператур, которые возникают внутри блочных пенопластов во время производства, может произойти частичное сильное пригорание.
IONOL CP очень эффективен и мобильен, а также предотвращает пригорание.

Таким образом, стало возможным производство неповрежденной и не обесцвечивающейся пены.
В зависимостиот применения оптимальная дозировка составляет 0,1- 1,0 php.
В соответствии с главой XXXIX правил BfR BHT рекомендуется в качестве антивозрастного средства для готовых изделий, изготовленных из полиуретанов.

Печатные краски:
Срок годностичернил printin g может быть сокращен в результате окисления.
Во время обработки могут произойти физические изменения.

Использование IONOL CP оказывает положительное влияние на стабильность, стойкость к выравниванию, а также на осветляющие и отверждающие свойства печатных красок.
Прилитографической печати IONOL CP предотвращает образование кожицы и ускоряет процесс высыхания.
Средние количества, подлежащие использованию, составляют 0,5 – 1,0%.

Применение IONOL CP:
IONOL CP - это маслорастворимый антиоксидант, широко используемый в стране и за рубежом.
Хотя IONOL CP токсичен, IONOL CP обладает сильной антиоксидантной способностью, хорошей термостойкостью и стабильностью, не имеет специфического запаха, не вызывает цветной реакции ионов металлов и имеет низкую цену, всего 1/8 ~ 1/5 BHA.

Обычно IONOL CP используется в сочетании с BHA и лимонной кислотой или другимиорганическими кислотами в качестве синергиста.
Китайские продукты можно использовать для производства пищевого масла, жареной пищи, печенья, лапши быстрого приготовления, ореховых консервов, сухих рыбных продуктов с максимальным содержанием 0,2 г/кг.
IONOL CP также обладает определенным антибактериальным действием, но слабее, чем BHA.

Характеристики IONOL CP:
IONOL CP представляет собой белый кристаллический антиоксидант и относится к группе не окрашивающих, стерически затрудненных фенолов.
IONOL CP в основном используется для стабилизации полимеров, которые вступают в контакт с пищевыми продуктами и / илипитьевой водой, полиолами, полиуретанами, клеями и горячими расплавами для возможного контакта с пищевыми продуктами, пахучими веществами и / или парфюмерией, пищевыми продуктами и печатными красками.

Существует BfR (ранее BGA, BgVV), одобрение FDA для IONOL CP, а также продукт соответствует всем требованиям, установленным в Регламенте 231/2012 в отношении спецификаций для пищевых добавок, в частности, критериям для E321.
Кроме того, IONOL CP соответствует аналитическим требованиям FCC (Food Chemical Codex) и Фармакопей.

ИОНOL CP представляет собой бесцветный, белый или не совсем белый кристалл или кристаллический порошок.
IONOL CP легко растворим в ацетоне, растворим в этаноле, нерастворим в воде и пропиленгликоле.

Температура замерзания:
Температура замерзания IONOL CP (General 0613) составляет 69~ 70 °C.

AbsКоэффициент поглощения Абс:
Возьмите IONOL CP, точное взвешивание, плюс растворение в этаноле и количественное разведение, чтобы получить раствор, содержащий около 50 мг на л/ л. Согласно УФ-видимой спектрофотометрии (общее правило 0 @1), поглощение измеряли при длине волны 278 нм, а коэффициент поглощения (dish) составлял от 80,0 до 90. 0.

Природа IONOL CP:
IONOL СР представляет собой бесцветный кристаллический или белый кристаллический порошок, без запаха, вкуса.
IONOL CP растворим в этаноле (25%, 25 °C), ацетоне (40%), бензоле (40%), соевом масле, хлопковом масле, нерастворим в воде, глицерине, пропиленгликоле.
IONOL CP легкий, термостойкий, при нагревании может улетучиваться с водяным паром, ион металла не меняет цвет.

Способ приготовления IONOL CP:
п-крезол итрет-бутиловый спирт растворяются при нагревании, а фосфорная кислота используется в качестве катализатора для реакции при определенной температуре.
Продукт реакции сначала промывают раствором гидроксида натрия до щелочного состояния, затем промывают водой до нейтрального состояния и, наконец, дистиллируют, при перекристаллизации получают дибутилгидрокситолуол.
Или изобутилен смешивают с крезолом и концентрированной серной кислотой, проводят реакцию при определенной температуре в течение определенного времени, и сырой продукт нейтрализуют, а затем сырой продукт растворяют в этаноле, добавляя тиомочевину, горячую фильтрацию, отжимную сушку, полученную сушкой.

Дифференциальный диагноз IONOL ХП:
В хроматограмме, записанной в разделе "Определение содержания", время удержания основного пика исследуемого раствора должносоответствовать времени удержания основного пика эталонного раствора.
Инфракрасный спектр поглощения IONOL CP должен соответствовать спектру поглощени�� эталонного продукта (Общее правило 0402).

Реакционный поток IONOLа CP:
Современные представления оразложении органических соединений (например, полимеров в пластмассах, синтетических или природных масел в смазочных материалах или ненасыщенных жирных кислот в пищевых продуктах) исходят из того факта, что разложение инициируется образованием углеводородных радикалов R.

Эта реакциявызывается теплом, светом и/или механической энергией:
R-H + инициатор -----> R

В реакции распространения цепи радикал R реагирует с атмосферным кислородом с образованием перекисного радикала R-OO, а последний с дополнительной молекулой углеводородов с образованием радикала R иперекисного соединения R-OOH.

R + O2 -----> R-OO
R-OO + R-H -----> R-OOH + R

Радикал R, образовавшийся на второй стадии реакции, далее вступает в цепную реакцию с кислородом в соответствии с уравнением реакции, подробно изложенным на предыдущей странице.
Перекись R-OOH дляmed на второй стадии реакции может разлагаться на альдегиды, кетоны и карбоновые кислоты и, в зависимости от типа поврежденного органического соединения, вызывать изменение цвета, коррозию или неприятный запах (например, прогорклые жиры).

Описанная выше цепная реакция может быть остановлена так называемой рекомбинацией радикалов.
Вероятность такой цепной реакции очень мала, так что радикальное разложение органических соединений не может остановиться без добавления антивозрастных средств.
AntiАнтивозрастные средства на основе стерически затрудненных фенолов действуют как поглотители радикалов, то есть они непосредственно вмешиваются в процесс разложения радикалов, химически связывая радикалы и предотвращая цепную реакцию распространения.

Хранение IONOL CP:
Срок годности IONOL CP составляет 24 месяца при правильной упаковке и хранении (в сухом, прохладном, хорошо проветриваемом помещении, при температуре <50 °C).
Несоблюдение этих требований может привести к пожелтению.

Стандартная упаковка IONOL CP:
Бумажные пакеты с полиэтиленовой подкладкой, 25 кг нетто, упакованные в термоусадочнуюпленку на поддонах (вес нетто: 750 кг или 1000 кг) или 20 кг нетто, упакованные в термоусадочную пленку на поддонах (вес нетто: 1000 кг).
Бочонки с волокном, 40 кг нетто.
Биг-бэги, 500/1000 кг нетто.

Меры первой помощи IONOL CP:

Общие меры первой помощи:
Никогда не давайте ничеговнутрь человеку, находящемуся без сознания.
Если вы чувствуете недомогание, обратитесь к врачу (по возможности покажите этикетку).

Меры первой помощи после вдыхания:
Обеспечьте дыхание свежим воздухом.
Дайте пострадавшему отдохнуть.

Меры первой помощи при контакте с кожей:
ReПереместите пострадавшую одежду и промойте все открытые участки кожи мягким мылом и водой, а затем смойте теплой водой.

Меры первой помощи при попадании в глаза:
Немедленно смойте большим количеством воды.
Обратитесь к врачу, если боль, мигание или покраснение не проходят.

Меры первой помощи после приема внутрь:
Прополоскать рот.
Не вызывайте рвоту.
Обратитесь за неотложной медицинской помощью.

Противопожарные мероприятия IONOL CP:

Подходящие средства пожаротушения:
Пена.
Сухой порошок.
Углекислый газ.
Брызги воды.
Песок.

Неподходящие средства пожаротушения:
Не используйте сильную струю воды.

Особые опасности, связанные с данным веществом или смесью:

Пожароопасность:
Не классифицируется как легковоспламеняющийся, но будет гореть.

Опасные продукты разложения при пожаре:
Моноксид углерода.
Углекислый газ.

Советы для пожарных:

Инструкции по пожаротушению:
Используйте водяные брызги или туман для охлаждения открытых контейнеров.
Соблюдайте осторожность при тушении любого химического пожара.
Не допускайте попадания противопожарной воды в окружающую среду.

ProЗащита при тушении пожара:
Не входите в зону пожара без надлежащего защитного снаряжения, включая средства защиты органов дыхания.

Идентификаторы IONOL CP:
Химическое название: 2,6-Ди-трет-бутил-4-метилфенол
CAS-номер: 128-37-0
Молекулярный вес: 220,4 г/моль

Форма продукта: Веществоoduct form: Substance
Название вещества: IONOL CP
Химическое название: 2,6-ди-трет-бутил-п-крезол
Номер ЕС: 204-881-4
CAS-номер: 128-37-0
Регистрационный номер REACH: 01-2119565113-46
Формула: C15H24O
Синонимы: 2,6-ди-терк-бутил-4-метилфенол

Типичные свойстваIONOL CP:
Внешний вид: Белое кристаллическое твердое визуальное
Температура кипения при 1013 ГПа: 265 °C
Насыпная плотность: 0,66 кг/л
Плотность при 80°C: 0,899 г/мл
Температура вспышки: 127°C ASTM D93
Показатель преломления: 1,4859
Растворимость в воде при 25°C: 0,6 мг/л
Растворимость вацетоне при 20°C: > 50 %
Растворимость в хлороформе при 20°C: > 50%
Растворимость в гептане при 20°C: 47,8 %
Растворимость в метаноле при 20°C: 26,6 %
Растворимость в толуоле при 20°C: > 50%

Физическое состояние: Твердое
Внешний вид: Кристаллический.
Цвет: Белый.
Запах: Характерный.
Температура плавления: 70 °C
Температура кипения: 265 °C (Справочник и/или научные статьи)
Температура вспышки: 127 °C (Справочник и/или научные статьи)
Температура самовоспламенения: Не применимо
Воспламеняемость (твердое вещество, газ): Не воспламеняется.
Давление параe: 3,82 Па (24,85 ºC)
Относительная плотность: 1,048 (Справочник и/или научные статьи)
Растворимость: В воде: 0,6 г/мл (Справочник и/или научные статьи)
Журнал военнопленных: 5.2 (Справочник и/ или научные статьи)
Вязкость, кинематическая: 3,47 сСт (80 °С), 1,54 сСт (120 °С), 0,920 сСт (160 °С) (Справочник и/или научные статьи)
Окислительные свойства: Исследование не требуется проводить, поскольку вещество не способно вступать в реакцию
экзотермически с горючими материалами.
Нижний предел взрываемости (LEL): 7,5 г/м3

Молекулярнаяформула: C15H24O
Молярная масса: 220,35
Плотность: 1.048
Температура плавления: 69-73°C (лит.)
Точка соединения: 265 °C (лит.)
Температура вспышки: 127 °C
Растворимость в воде: нерастворимая
Растворимость: Растворим в толуоле, растворим в ацетоне, этаноле, бензоле, эфире, изопропаноле, метаноле, 2-бутаноне, эфире этиленгликоля, петролейном эфире и других органических растворах, нерастворим в воде и растворе щелочи.
Давление пара: <0,01 мм рт. ст. (20 °C)
Плотность пара: 7,6 (по сравнению с воздухом)
Возникновение: Бесцветный кристаллический или белый кристаллическийпорошок
Цвет: белый
Запах: слабый характерный запах
Предел воздействия: ACGIH: TWA 2 мг / м3 NIOSH: TWA 10 мг / м3
Мерк: 14,1548
Артикул: 1911640
pKa: pKa 14 (H2Ot = 25c = 0,002-0,01) (неопределенный)
Условия хранения: 2-8 °C
Стабильность: Стабильная, но светочувствительная. Несовместим с хлоридами кислот, ангидридами кислот, латунью, медью, медными сплавами, сталью, щелочами, окислителями. Горючий.
Показатель преломления: 1,4859
ЛЕИ: MFCD00011644

Технические характеристики IONOL CP:
Чистота: минимум 99,8 вт/вт-%
Температура плавления: 70±1ºC
WaterСодержание воды: не более 0,12 вт/вт-%
Цвет (30% мас./мас.% в ацетоне): не более 30 apha
Сульфатная зола: не более 0,002 вт/вт-%

Другие продукты IONOL:
IONOL CP
IONOL 75
IONOL 75S30
IONOL 75T30
IONOL BS35
IONOL BT45
IONOL BF200
IONOL BF350
IONOL BF1000
IONOL K65
IONOL K72
IONOL K78
IONOL K98
IONOL 99
IONOL 103
IONOL 135
IONOL 220
IONOL 220 AH
IONOL PET FOOD
IONOL AQUA 50
IONOL CPS
IONOL CP MOLTEN
IONOL 175N
IONOL 175N PLUS
IONOL FEED 501
IONOL FEED 101
IONOL 200N
IONOL CPF
IONOL CPA
IONOL CPC
IONOL CPD
IONOL FEED 502
IONOL CPA FLAKES
IONOL LC
IONOL BHT TECHNICAL GRADE
IONOL BHT TECHNICAL FLAKES

Синонимы IONOL CP:
bht
BHT
dbpc
Т501
2,6-DBPC
BHTOX-BHT
ralox bht
BHT (МЕШКИ)
bht (мешки)
Антиоксидант 264
501 антиоксидант
антиоксидант bht
BHT, ГРАНУЛИРОВАННЫЙ, FCC
bht, гранулированный, fcc
Антиоксидант T501
антиоксидант bht
Аниониоксидант BHT
дибутилметилфенол
бутилгидрокситолуол
ionol cp-антиоксидант
bht, гранулированный, технический
BHT, ГРАНУЛИРОВАННЫЙ, ТЕХНИЧЕСКИЙ
2-бутил-3-метилфенол
3-бутил-4-метилфенол
бутилатd гидрокситолуола
бутилгидрокситолуол bht
Бутилированный гидрокситолуол
2,6-Ди-трет-бути-п-крезол
бутилированный гидрокситолуол
ди-трет-бутил-пара-крезол
2,6-ди-трет-бутил-п-крезол
2,6-ди-трет-бутил-4-крезол
2,6-ди-трет. бутил-п-крезол
ди-трет-бутилгидрокситолуолoluene
Резиновый антивозрастной агент 264
2,6-дитертиарибутилпаракрезол
2,6-Ди-трет-бутил-4-метилфенол
4-метил-2,6-ди(трет-бутил)фенол
3,5-ди-трет-4-бутилгидрокситолуол
2,6-ди-трет-бутил-4-метилфенол
БУТИЛАТГИДРОКСИТОЛУОЛ ГРАНУЛИРОВАННЫЙ NF
бутилатгидрокситолуолгранулированный, nf
bht (ди-трет.-бутил-4-гидрокситолуол)
2,6,-ди-трет-бутил-4-метилфенол cp
3,5-ди-трет-4бутилгидрокситолуол (bht)
2,6-ди- (трет-бутил)-4-метилфинол-d21
Производитель бутилированного гидрокситолуола
2,6-дитербутил-4-метилфенол[128,37,0]
2,6-бис(1,1-диметилэтил)-4-метилфенол
2,6-дитеритрийбутил-4-метилфенол (bht)
внт 2,6 - ди - трет - бутил -4-метилфенол
бутилерет гидрокситолуол (2,6-ди-трет-бутил-п-крезол)
IONOL CP128-37-0204-881- 4C15H24O
IONOL(R) CPA
IONOL (R) CPD
Iонол(R) CPC
IONOL (R) CPM
2,6-бис(1,1-диметилэтил)-4-метилфенол
2,6-ди-трет-бутил-п-крезол
бутилированный гидрокситолуол
dbpc
ralox bht
бутилгидроксит��луол
2,6-ди-трет. бутил-п-крезол
дибутилметилфенол
bht
бутилгидрокситолуол bht
4-метил-2,6-di(трет-бутил)фенол
антиоксидант bht
антиоксидант bht
2,6-ди-трет-бутил-4-крезол
2,6-ди-трет-бутил-4-метилфенол
501 антиоксидант
бутилированный гидрокситолуол
бутилерет гидрокситолуол (2,6-ди-трет-бутил-п-крезол)
2,6-ди- (трет-бутил)-4-метилфинол-d21
3,5-ди-трет-4бутилгидрокситолуол (bht)
bht (мешки)
bht fcc|nf
bht, гранулированный, fcc
bht, гранулированный, технический
бутилатгидрокситолуол гранулированный nf
ди-трет-бутилгидрокситолуол
2,6-дитеритрийбутил-4-метилфенол (bht)
бутилированный гидрокситолуол (bht и 2,6-dbpc)
ди-трет-бутил-пара-крезол
2,6-дитертиарибутилпаракрезол
bht (ди-трет.-бутил-4-гидрокситолуол)
ionol cp-антиоксидант
2,6-дитербутил-4-метилфенол[128,37,0]
внт 2,6 - ди - трет - бутил -4-метилфенол
2,6,-ди-трет-бутил-4-метилфенол cp
BHTOX-BHT
Аниониоксидант BHT
Т501
Антиоксидант 264
2,6-DBPC
3,5-ди-трет-4-бутилгидрокситолуол
Антиоксидант T501
3-бутил-4-метилфенол
2-бутил-3-метилфенол
2,6-Ди-трет-бути-п-крезол
Резиновый антивозрастной агент 264

Iron 3 Chloride; Iron(III) chloride; Iron trichloride; Ferric chloride; Molysite; Flores martis cas no: 7705-08-0

isopropanol; 2-Propanol; sec-Propyl alcohol; Isopropyl alcohol; Propan-2-ol; 67-63-0; 2-Hydroxypropane; Dimethylcarbinol; 1-Methylethanol; 2-Propyl alcohol CAS NO:67-63-0

IPBC (Iodopropynyl butylcarbamate) Iodopropynyl butylcarbamate Iodopropynyl Butyl Carbamate (IPBC) is a water-soluble preservative used globally in the paints & coatings, wood preservatives, personal care, and cosmetics industries. IPBC is a member of the carbamate family of biocides.[1] IPBC was invented in the 1970s and has a long history of effective use as an antifungal technology. History IPBC was initially developed for use in the paint & coatings industry as a dry-film preservative to protect interior and exterior coatings from mold, mildew, and fungal growth, while also offering cost performance and sustainability benefits. IPBC exhibits efficacy against a broad spectrum of fungal species, typically at very low use levels. IPBC today is incorporated into a wide variety of interior and exterior paint formulations around the world. Use is restricted in some countries due to its toxicity, especially acute inhalation toxicity. IPBC is also becoming recognized as a contact allergen.[2] Uses IPBC is an effective fungicide at very low concentrations in cosmetic and other products, and has shown very low sensitivity in humans tested with this preservative. IPBC was approved in 1996 for use up to 0.1% concentrations in topical products and cosmetics. However, this preservative is mostly found in cosmetics at about one-eighth that level [Maier et al., 2009]. IPBC Toxicity and Safety Tests show it to be generally safe: When used properly in leave-on skin products, IPBC is extremely safe [Steinberg, 2002]. Previous to being approved for cosmetic use in 1996, extensive safety and toxicity tests were conducted on IPBC and their results were gathered along with earlier studies in a report of the Safety Assessment of IPBC by the Cosmetic Ingredient Review [CIR Final Report, Lanigan 1998]. This final report found IPBC to be a non-carcinogen with no genotoxicity and in reproductive and developmental toxicity studies using rats and mice, IPBC had no significant effect on fertility, reproductive performance, or on the incidence of fetal malformation [Lanigan, 1998]. Toxicity The study, "Final Report on the Safety Assessment of Iodopropynyl Butylcarbamate", discusses the results of 32 studies between 1990 and 1994 in 3,582 subjects using skin application of IPBC at relevant concentrations. [3] All 32 studies showed no evidence of contact sensitization compared to placebo controls, with the report stating "With each test formulation, a few panelists had erythema, edema, and/or a papular response, but overall, the results were negative." In addition, the study mentions two skin sensitivity studies on 183 children ages 3 – 12 yrs which showed no adverse effects as well as no significant irritation from IPBC. Since the early safety report, there have been a few reports of human skin sensitivity to IPBC in individual patients – all of which showed complete recovery after discontinuance of use of any product containing the IPBC which was presumably an allergen for these patients [Toholka & Nixon, 2014; Pazzaglia & Tosti, 1999]. Post-1996 tests of human sensitivity to IPBC have all shown quite low sensitivity, having overall reported human skin testing (patch test) on 53,774 subjects with only 491 of those subjects showing any reaction (0.8%) to IPBC. In every study, positive patch test reactions occurred in less than 1% of subjects tested in all but one study. This is a very low reaction rate, but it is not zero, and the industry reports this low rate of reaction even though in the largest study of 25,435 subjects over 69% of the reactions were either weak or doubtful [Warshaw et al., 2013a]. These combined studies showing prevalence of reaction below 1% means that IPBC at this time does not have the reaction rates necessary to be included as an allergen in standard allergy series. But, it remains under close monitoring as it is a relatively new preservative for cosmetic products and will presumably increase in usage [Sasseville, 2004]. Most human patch tests performed before 2004 were with 0.1% IPBC solutions, i.e. 10 times the concentration used in many cosmetic products. Some used 0.5% IPBC. In 2004, it was suggested that a better concentration for tests of this substance would be 0.2% [Brasch et al., 2004] and this has contributed to the diagnosis of more sensitizations to this substance [Martin-Gorgojo & Johansen, 2013]. One study showed significantly increased sensitivity between 2005 and 2010 using 0.5% IPBC in patch tests [Warshaw et al., 2013b]. See also Ingredients of cosmetics Iodopropynyl butylcarbamate Ipbc.svg Names IUPAC name 3-Iodoprop-2-yn-1-yl butylcarbamate Other names 3-Iodo-2-propynyl N-butylcarbamate; 3-Iodo-2-propynyl butylcarbamate; Iodocarb Identifiers CAS Number 55406-53-6 check 3D model (JSmol) Interactive image Abbreviations IPBC ChEBI CHEBI:83279 ☒ ChemSpider 55933 check ECHA InfoCard 100.054.188 PubChem CID 62097 UNII 603P14DHEB check Properties Chemical formula C8H12INO2 Molar mass 281.093 g·mol−1 IODOPROPYNYL BUTYLCARBAMATE IODOPROPYNYL BUTYLCARBAMATE is classified as : Preservative CAS Number 55406-53-6 EINECS/ELINCS No: 259-627-5 Restriction (applies to EU only): VI/56 COSING REF No: 34582 Chem/IUPAC Name: 3-Iodo-2-propynyl butylcarbamate Iodopropynyl Butylcarbamate What Is Iodopropynyl Butylcarbamate? Iodopropynyl Butylcarbamate, also known as IPBC, is a white or slightly off-white crystalline powder that contains iodine. It is used in a wide variety of cosmetics and personal-care products Why is Iodopropynyl Butylcarbamate used in cosmetics and personal care products? Iodopropynyl Butylcarbamate prevents or retards bacterial growth, thereby protecting cosmetics and personal-care products from spoilage. Follow this link for more information about how preservatives protect cosmetics and personal care products. Scientific Facts: Iodopropynyl Butylcarbamate is an internationally recognized preservative that has been used for years because of a wide field of application. The need for a broad-spectrum and safe preservative system for cosmetics has led to the development of several combinations of IPBC with other preservatives effective against a wide variety of organisms. IPBC is also used as a preservative in household products, paints, cements and inks. 3-iodo-2-propynyl butylcarbamate is an off-white solid. 3-iodoprop-2-yn-1-yl butylcarbamate is a carbamate ester that is carbamic acid in which the nitrogen has been substituted by a butyl group and in which the hydrogen of the carboxy group is replaced by a 1-iodoprop-2-yn-3-yl group. A fungicide, it is used as a preservative and sapstain control chemical in wood products and as a preservative in adhesives, paints, latex paper coating, plastic, water-based inks, metal working fluids, textiles, and numerous consumer products. It has a role as a xenobiotic, an environmental contaminant and an antifungal agrochemical. It is a carbamate ester, an organoiodine compound, an acetylenic compound and a carbamate fungicide. Molecular Weight of IPBC: 281.09 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) XLogP3-AA of IPBC: 2.1 Computed by XLogP3 3.0 (PubChem release 2019.06.18) Hydrogen Bond Donor Count of IPBC: 1 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Hydrogen Bond Acceptor Count of IPBC: 2 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Rotatable Bond Count of IPBC: 5 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Exact Mass of IPBC: 280.99128 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Monoisotopic Mass of IPBC: 280.99128 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Topological Polar Surface Area of IPBC: 38.3 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Heavy Atom Count of IPBC: 12 Computed by PubChem Formal Charge of IPBC: 0 Computed by PubChem Complexity of IPBC: 192 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Isotope Atom Count of IPBC: 0 Computed by PubChem Defined Atom Stereocenter Count of IPBC: 0 Computed by PubChem Undefined Atom Stereocenter Count of IPBC: 0 Computed by PubChem Defined Bond Stereocenter Count of IPBC: 0 Computed by PubChem Undefined Bond Stereocenter Count of IPBC: 0 Computed by PubChem Covalently-Bonded Unit Count of IPBC: 1 Computed by PubChem Compound of IPBC Is Canonicalized Yes Iodopropynyl Butylcarbamate Details It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. Its strong point is being effective against yeasts and molds, and as a nice bonus seems to be non-comedogenic as well. It is safe in concentrations of less than 0.1% but is acutely toxic when inhaled, so it's not the proper preservative choice for aerosol formulas like hairsprays. Used at 0.1%, Iodopropynyl Butylcarbamate has an extremely low rate of skin-irritation when applied directly for 24 hours (around 0.1% of 4,883 participants) and after 48 hours that figure was 0.5%, so it counts as mild and safe unless your skin is super-duper sensitive. iodopropynyl butylcarbamate Where is iodopropynyl butylcarbamate found? Iodopropynyl butylcarbamate is a preservative used in cosmetics, wet wipes (toilet paper), and other personal care products. It is also used as a biocide in paints, primers, and industrial coolants and cooling lubricants. How can you avoid contact with iodopropynyl butylcarbamate? Avoid products that list any of the following names in the ingredients: • Butyl-3-iodo-2-propynylcarbamate • Carbamic acid, butyl-3-iodo-2-propynyl ester • Iodopropynyl butylcarbamate • 3-Iodo-2-propynyl butylcarbamate • EPA Pesticide Chemical Code 107801 • BRN 2248232 • Caswell No. 501A • EINECS 259-627-5 • HSDB 7314 • 3-Iodo-2-propynyl butyl carbamate What are some products that may contain iodopropynyl butylcarbamate? Baby Care • Baby lotion • Baby wash and shampoo • Diaper rash cream • Flushable moist wipes Body Washes and Soaps • Cleansing towelettes • Makeup remover towelettes Cosmetics • Concealer • Eye lash tint • Liquid eye liner Hair Dye Hair Hair Styling Products • Gel • Hairspray • Pomade • Root lifter Industrial Coolants and Cooling Lubricants Lip Balm Lotions and Skin Care Products • Acne treatment • Anti-itch cream • Bar soap • Body lotion • Moisturizer • Wrinkle cream Paints and Stains Shampoos and Conditioners Shaving Creams and Gels Sunscreens Yard care • Insect killer • Weed killer Iodopropynyl butylcarbamate (IPBC) is an internationally recognized chemical that has been used for years because of its wide field of application. Initially used as a water-based paint and wood preservative and then in metalworking fluids, its role has expanded into the more recent uses in cosmetic products. The need for a potent, broad-spectrum, and safe preservative system in cosmetics allowed for the discovery of several combinations of IPBC effective against a wide variety of organisms. Although IPBC has claimed to be safe when used at concentrations less than 0.1%, the introduction of IPBC into cosmetics has led to several reports labeling IPBC as a potential new contact allergen. As the use of this seemingly safe preservative becomes vast, an increased number of cases of IPBC-induced contact allergy is likely.

Chemical name: 3-iodo-2-propynyl butyl carbomate Description; Nipacide IPBC 30 is a 30% active IPBC clear glycolic fungicide, Nipacide IPBC 30 has been developed for fungal dry film protection of water based coatings. Nipacide IPBC 30 can also be used for wet state, in-can fungal protection. Nipacide IPBC 30 is effective against a wide range of fungal and yeast species and exhibits some activity against gram negative and gram positive bacteria. Dry –film degradation in paints and decorative coatings can be avoided by using the correct dry-film fungicides at the most cost effective use level. Ideal dry-film properties achieved by Nipacide IPBC3 30 include: • High activity against a broad range of fungi and algae • Excellent activity at relatively low use concentrations • Carbendazim free • pH stable • UV stable • Low water solubility • Approved under the Biocidal Products Directive • Cost effective protection Applications; Nipacide IPBC 30 is recommended for protection of a wide range of coating applications including water based decorative paints, wood stains and colours. Nipacide IPBC 30 can also be used in solvent based applications. Increased antifungal activity can also be achieved by using Nipacide IPBC 30 for in-can use in adhesives grouts and sealants. Nipacide IPBC 30 is effective against a wide range of spoilage organisms effective over a wide pH range. Nipacide IPBC 30 should not be used in products heated above 400 C. Use level; Nipacide IPBC 30 should be evaluated in finished products at levels between 0.50% and 2.0% for dry film applications. The level of protection will depend on many factors including the end destination of coating, relative humidity, sun strength and others and can be determined by evaluation by our team of microbiologists at the Microbiology facility. For in-can antifungal activity Nipacide IPBC 30 should be evaluated between 0.10% and 0.30%. Microbiological data; Even though Nipacide IPBC 30 is designed for dry-film applications it also exhibits activity against a wide range of bacteria, fungi and yeast. This can be demonstrated by the following MIC data. Chemical compatibility; Nipacide IPBC 30 is compatible with most raw materials used in the manufacture of industrial and decorative coatings. Nipacide IPBC 30 compatibility should always be checked and evaluated before use.

IPHA 15% Isopropyl alcohol (IPHA 15%) (IUPAC name propan-2-ol; commonly called isopropanol or 2-propanol) is a compound with the chemical formula CH3CHOHCH3.[8] It is a colorless, flammable chemical compound with a strong odor. As an isopropyl group linked to a hydroxyl group, it is the simplest example of a secondary alcohol, where the alcohol carbon atom is attached to two other carbon atoms. It is a structural isomer of 1-propanol and ethyl methyl ether. It is used in the manufacture of a wide variety of industrial and household chemicals, and is a common ingredient in chemicals such as antiseptics, disinfectants, and detergents. isopropyl alcohol (IPHA 15%) is also known as 2-propanol, sec-propyl alcohol, IPA, or isopropanol. IUPAC considers isopropanol an incorrect name as the hydrocarbon isopropane does not exist Recommended use: Monomer stabilizer. Polymerization chainstopper. Synthesis intermediate. Photochemical additive. For industrial use. Other names of isopropyl alcohol (IPHA 15%), colorless, flammable liquid are known. For example, in the lab it may be simply denoted by isopropanol, isopro, iso, isopropyl, or acronym IPA. It is also an inorganic compound sometimes called 2-propanol, possibly referred to as an isomer, also known as propanol. Of course, isopropyl alcohol (IPHA 15%) is most commonly known as simple spirit. isopropyl alcohol (IPHA 15%), also known as isopropanol; clear, mixture of ethanol and acetone has an odor; it is a flammable alcohol. It forms solutions in any proportion with water, ethanol, acetone, chloroform and benzene, can be subjected to all typical reactions of secondary alcohols, and gives strong reactions with strong oxidizing agents. isopropyl alcohol (IPHA 15%), which is used as a low cost solvent in many applications, is similar to ethyl alcohol in terms of solvent properties and evaporation rate. If it burns, it decomposes to form carbon monoxide, which is toxic. IPHA 15% is useful for use in lacquers, inks and thinners in terms of its high latent solvent power, moderate evaporation rate and many other solvents it forms for cellulose nitrate, cellulose acetate butyrate and cellulose acetate procyanate. The use of isopropyl alcohol (IPHA 15%) in the production of monoisoprolamine for herbicides is the fastest growing segment in terms of use, and its use as a solvent in coatings and inks remains either the same or increases slightly. IPHA 15% is usually used by diluting with water when necessary for cleaning and stain removal. IPHA 15% is also used to remove oxidation and residual resin residues in electronic circuit boards. As a solvent IPHA 15%; in extraction and purification of natural products such as vegetable and animal oils, gum resins, waxes, colorants, flavors, alkaloids, vitamins and alginates; as a carrier in the production of foodstuffs; in purification, crystallization and precipitation of organic chemicals; It finds application in synthetic polymers such as phenolic varnishes and nitrocellulose lacquers. Also as a solvent; Participates in formulations of cosmetics, hair tonics, perfumes, skin lotions, hair dye rinse, skin cleaners, deodorant, nail polish, shampoo, hair sprays, air fresheners. As coating and paint solvent; It finds application in the production of cement, primer, paint and ink and acts as a cleaning and drying agent in liquid soap and detergent. isopropyl alcohol (IPHA 15%) (IPA); It is also used in the production of acetone and its derivatives and other chemicals such as isopropyl acetate, isopropylamine, diisopropyl ether, isopropyl xanthate, fatty acid esters, herbicidal esters and aluminum isopropoxide. Other Area of ​​Usage; It can be considered as a cooling agent in beer production, dehydrating agent in polyvinyl fluoride production, polymerization modifier and as a flavoring agent in home tobacco and personal care products. About IPHA 15% IPHA 15% has not been registered under the REACH Regulation, therefore as yet ECHA has not received any data about IPHA 15% from registration dossiers. IPHA 15% is used by professional workers (widespread uses), in formulation or re-packing and at industrial sites. Widespread uses by professional workers IPHA 15% is used in the following products: washing & cleaning products and water treatment chemicals. ECHA has no public registered data on the types of manufacture using IPHA 15%. Other release to the environment of IPHA 15% is likely to occur from: indoor use as reactive substance. Uses at industrial sites IPHA 15% is used in the following products: pH regulators and water treatment products, water treatment chemicals, adhesives and sealants and polymers. IPHA 15% is used for the manufacture of: rubber products. Release to the environment of IPHA 15% can occur from industrial use: as processing aid and as processing aid. The pure N-Isopropylhydroxylamine (IPHA 15%) is a white crystalline flake; however, it is sold as a 15% solution in water [2]. The aqueous solution is colourless with a slight amine odour [2]. IPHA 15% is marketed as a free-radical scavenger and uses in acrylonitrile-butadiene rubber and styrene-butadiene rubber manufacturing under the trade name CHAINGUARDTMI-15 Hydroxylamine. It is also used as an oxygen scavenger and metal passivator to control corrosion in boilers and marketed with the trade name HYDROGUARDTM I-15 Hydroxylamine [2]. IPHA 15% may also be used in other applications, such as photographic processing, “popcorn” polymer inhibition, monomer stabilization, reducing agent, dye affinity aid; ORE recovery (chelator) and as a synthetic building block [1]. The estimated rate constant of oral absorption of IPHA 15% through human gastrointestinal tract (jejunum) is 0.014 min-1by ACD/ADME Suite version 5.0 (Advanced Chemistry development, Toronto, ON, Canada). This low rate of oral absorption is consistent with the pKa (6.16) of the basic (pH of 15% aqueous solution = 10.6) compound. Most of IPHA 15% will remain ionized in human jejunum which has a pH of 6.5, lowering oral absorption. Even with the slow rate of oral absorption, the overall amount of absorption is estimated to be 99% (ACD/ADME Suite). It has also been estimated to have a moderate volume of distribution of 1.1 L/kg in human, consistent with the low log Kow for this compound. Similarly, plasma protein binding of IPHA 15% is estimated to be ~52% in humans by ACD/ADME Suite. No toxicological information for IPHA 15% is found for comparison with the rate of absorption and acute toxicity. The steady-state dermal permeability coefficient of aqueous IPHA 15% through human epidermis has been estimated to be 7.42 x 10-4cm/h by Dermwin version 2.01 (EPI Suite version 4.0). On the basis of this data, negligible penetration of dermally applied IPHA 15% is expected. However, no dermal toxicity data are available for comparison. Distribution Due to its basic nature (pH = 10.6 of 15% aqueous solution [1]), non-lipophilicity (log Kow= 0.15) and moderate plasma protein binding (~52%), a moderate volume of distribution (1.1 L/kg) is estimated for IPHA 15% in humans by ACD/ADME Suite. Accumulation Due to moderate plasma protein binding and low volume of distribution, IPHA 15% is expected to have very low bioaccumulation potential. Metabolism No data on the metabolism of IPHA 15% in rat or other species has been reported. As shown in the chemical structure, IHPA contains the two moieties of isopropyl and hydroxyamine. Therefore, it’s metabolism will be predicted based on the metabolism of both isopropyl and hydroxyamine. The isopropyl group can be metabolized to by cytochrome P450 via hydroxylation, this will lead to the hydroxylated IPHA 15% metabolite. The hydroxyamine group is expected to be metabolically stable, and will not be further metabolized by cytochrome P450 or other Phase I or II enzymes,in vivoorin vitro. Based on these rationale, the potential metabolite of IPHA 15% will be hydroxylated isopropylhydroxyamine. Excretion Both IPHA 15% and the hydroxylated isopropylhydroxyamine metabolite are water-soluble; therefore, would be expected to excreted primarily in urine. Summary This analysis estimated a relative dermal absorption of 3.5% to 7.4% of the applied dose for an aqueous solution of N-isopropylhydroxylamine (IPHA 15%), CAS No. 5080-22-8. A literature search of several databases did not find experimental dermal absorption results for IPHA 15%. QSARs were used to estimate the skin permeability coefficient and which was then extrapolated to a relative dermal absorption. Although one analog of IPHA 15% was found, it did not have experimental dermal absorption results so read across could not be applied. Introduction An evaluation of the potential human dermal absorption was conducted for IPHA 15% in order to refine the DNEL derivation for the ANGUS Chemical registration of IPHA 15% for REACH. The previous DNEL analysis conservatively assumed 100% relative dermal absorption. 1. Physical state. The substance is in aqueous solution under the use conditions; liquids are taken up more readily than dry particulates. 2. Exposure. IPHA 15% is used in 15% aqueous solutions in HYDROGUARD and CHAINGUARD, these products are for industrial use in water-treatment operations and polymer reaction-control applications. It was suggested that transferring the chemical from a product container into a process tank would present the highest exposure potential; other tasks would expose the worker to more dilute solutions. 3. Physical and chemical properties. IPHA 15% has a molecular weight of 75. Molecular weight is an indicator of the molecule volume and the penetration rate of a molecule into the skin is inversely proportional to its volume. One would not expect the molecular weight of IPHA 15% to significantly limit is dermal penetration. 4. Octanol/water partition coefficient, Kow. The estimated log Kow for IPHA 15% is 0.15 and it is classified as lipophobic. The Kow, is the ratio of the chemical concentration in octanol to its concentration in water, with octanol acting as a model for the lipids (fats) in an organism. A log Kow value below 0 will limit penetration into the stratum corneum and limit dermal absorption. A high log Kow value corresponds to a highly lipophilic chemical which will tend to partition into the skin lipids rather than the aqueous matrix. 5. Vapor pressure. If a substance has a significant vapor pressure it may evaporate before it has time to penetrate the skin or the skin penetration may be significantly reduced. The vapor pressure for IPHA 15% was reported as 0.26 mm Hg at 20°C (15% aqueous IPHA 15% in CHAINGUARD™ ) and evaporation may reduce the dermal load and possibly limit the dermal penetration. 6. Lag time. This is the experimentally determined duration for the substance to penetrate the skin and be measured in the receptor fluid in the test cell. A long lag time may be due to the stratum corneum providing a barrier which prevents substance penetration. A long lag time may also be due to the substance penetrating slowly or formation of a skin residue. The calculations using the skin permeability coefficient assume the substance immediately penetrates the skin and do not consider the lag time in uptake. The USEPA DERMWIN v2.01 predicted tau as 0.281 hr, tau is lag time in update; it predicted t*as 0.674 hr, t* is time to steady state penetration. 7. Water solubility. This limits the substance concentration in an aqueous solution. Substances which are soluble tend to penetrate the skin well. Substances with a high water solubility may be too hydrophilic to cross the stratum corneum. IPHA 15% has a high predicted water solubility and it is hydrophilic. 8. Water dissociation. Substances which dissociate (ionize) in water do not tend to penetrate the skin well. IPHA 15% does not ionize. Therefore, using the REACH stepwise approach one would expect the low log Kow and the hydrophilic nature of IPHA 15% to limit its dermal penetration. Evaporation may reduce the dermal load and possibly limit the dermal penetration. IPHA 15% is an organic compound, an isomer of n-propanol, aliased dimethylmethanol, 2-propanol. IPHA 15% is a colorless, transparent liquid with a scent like a mixture of ethanol and acetone. Soluble in water, also soluble in most organic solvents such as alcohol, ether, benzene, chloroform, etc. IPHA 15% has a wide range of uses as an organic raw material and solvent. 1）As a chemical raw material, it can produce acetone, hydrogen peroxide, methyl isobutyl ketone, diisobutyl ketone, isopropylamine, diisopropyl ether, isopropyl chloride, and fatty acid isopropyl ester and chloro fatty acid isopropyl ester. 2）In the fine chemical industry, it can be used to produce isopropyl nitrate, isopropyl xanthate, triisopropyl phosphite, aluminum isopropoxide, pharmaceuticals and pesticides, etc. It can also be used to produce diisopropanone, isopropyl acetate and Thymol and gasoline additives. 3）IPHA 15% Can be used to produce coatings, inks, extractants, aerosols, etc. 4) In the electronics industry, IPHA 15% can be used as a cleaning and degreasing agent. 5) In the oil and fat industry, the extractant of cottonseed oil can also be used for degreasing of animal-derived tissue membranes. IPHA 15% (IUPAC name propan-2-ol; commonly called isopropanol or 2-propanol) is a colorless, flammable chemical compound (chemical formula CH3CHOHCH3) with a strong odor.[8] As an isopropyl group linked to a hydroxyl group, it is the simplest example of a secondary alcohol, where the alcohol carbon atom is attached to two other carbon atoms. It is a structural isomer of 1-propanol and ethyl methyl ether. IPHA 15% is used in the manufacture of a wide variety of industrial and household chemicals and is a common ingredient in chemicals such as antiseptics, disinfectants, and detergents. Names of IPHA 15% IPHA 15% IPHA 15% is also known as 2-propanol, sec-propyl alcohol, IPA, or isopropanol. IUPAC considers isopropanol an incorrect name as the hydrocarbon isopropane does not exist. Properties of IPHA 15% IPHA 15% is miscible in water, ethanol, ether, and chloroform. It dissolves ethyl cellulose, polyvinyl butyral, many oils, alkaloids, gums and natural resins.[9] Unlike ethanol or methanol, IPHA 15% is not miscible with salt solutions and can be separated from aqueous solutions by adding a salt such as sodium chloride. The process is colloquially called salting out, and causes concentrated IPHA 15% to separate into a distinct layer. IPHA 15% forms an azeotrope with water, which gives a boiling point of 80.37 °C (176.67 °F) and a composition of 87.7 wt% (91 vol%) IPHA 15%. Water–IPHA 15% mixtures have depressed melting points.[10] It has a slightly bitter taste, and is not safe to drink. IPHA 15% becomes increasingly viscous with decreasing temperature and freezes at −89 °C (−128 °F). IPHA 15% has a maximal absorbance at 205 nm in an ultraviolet–visible spectrum. Reactions of IPHA 15% IPHA 15% can be oxidized to acetone, which is the corresponding ketone. This can be achieved using oxidizing agents such as chromic acid, or by dehydrogenation of IPHA 15% over a heated copper catalyst: (CH3)2CHOH → (CH3)2CO + H2 IPHA 15% is often used as both solvent and hydride source in the Meerwein-Ponndorf-Verley reduction and other transfer hydrogenation reactions. IPHA 15% may be converted to 2-bromopropane using phosphorus tribromide, or dehydrated to propene by heating with sulfuric acid. Like most alcohols, IPHA 15% reacts with active metals such as potassium to form alkoxides that can be called isopropoxides. The reaction with aluminium (initiated by a trace of mercury) is used to prepare the catalyst aluminium isopropoxide.[14] History of IPHA 15% In 1920, Standard Oil first produced IPHA 15% by hydrating propene. Its major use at the time was not rubbing alcohol but for oxidation to acetone, whose first major use was in World War I for the preparation of cordite, a smokeless, low explosive propellant. Production of IPHA 15% In 1994, 1.5 million tonnes of IPHA 15% were produced in the United States, Europe, and Japan.[16] It is primarily produced by combining water and propene in a hydration reaction or by hydrogenating acetone. There are two routes for the hydration process and both processes require that the IPHA 15% be separated from water and other by-products by distillation. IPHA 15% and water form an azeotrope, and simple distillation gives a material that is 87.9% by weight IPHA 15% and 12.1% by weight water.[18] Pure (anhydrous) IPHA 15% is made by azeotropic distillation of the wet IPHA 15% using either diisopropyl ether or cyclohexane as azeotroping agents.[16] Biological of IPHA 15% Small amounts of IPHA 15% are produced in the body in diabetic ketoacidosis.[19] Indirect hydration of IPHA 15% Indirect hydration reacts propene with sulfuric acid to form a mixture of sulfate esters. This process can use low-quality propene, and is predominant in the USA. These processes give primarily IPHA 15% rather than 1-propanol, because adding water or sulfuric acid to propene follows Markovnikov's rule. Subsequent hydrolysis of these esters by steam produces IPHA 15%, by distillation. Diisopropyl ether is a significant by-product of this process; it is recycled back to the process and hydrolyzed to give the desired product. CH3CH=CH2 + H2O H2SO4⟶ (CH3)2CHOH Direct hydration of IPHA 15% See also: Heteropoly acid Direct hydration reacts propene and water, either in gas or liquid phase, at high pressures in the presence of solid or supported acidic catalysts. This type of process usually requires higher-purity propylene (> 90%).[16] Direct hydration is more commonly used in Europe. Hydrogenation of acetone IPHA 15% may be prepared via the hydrogenation of acetone, however this approach involves an extra step compared to the above methods, as acetone is itself normally prepared from propene via the cumene process.[16] It may remain economical depending on the value of the products. A known issue is the formation of MIBK and other self-condensation products. Raney nickel was one of the original industrial catalysts, modern catalysts are often supported bimetallic materials. This is an efficient process and easy Uses of IPHA 15% One of the small scale uses of isopropanol is in cloud chambers. Isopropanol has ideal physical and chemical properties to form a supersaturated layer of vapor which can be condensed by particles of radiation. In 1990, 45,000 metric tonnes of IPHA 15% were used in the United States, mostly as a solvent for coatings or for industrial processes. In that year, 5400 metric tonnes were used for household purposes and in personal care products. IPHA 15% is popular in particular for pharmaceutical applications,[16] due to its low toxicity. Some IPHA 15% is used as a chemical intermediate. IPHA 15% may be converted to acetone, but the cumene process is more significant. [16] Solvent of IPHA 15% IPHA 15% dissolves a wide range of non-polar compounds. It also evaporates quickly, leaves nearly zero oil traces, compared to ethanol, and is relatively non-toxic, compared to alternative solvents. Thus, it is used widely as a solvent and as a cleaning fluid, especially for dissolving oils. Together with ethanol, n-butanol, and methanol, it belongs to the group of alcohol solvents, about 6.4 million tonnes of which were used worldwide in 2011.[20] IPHA 15% is commonly used for cleaning eyeglasses, electrical contacts, audio or video tape heads, DVD and other optical disc lenses, removing thermal paste from heatsinks on CPUs and other IC packages, etc. Intermediate IPHA 15% is esterified to give isopropyl acetate, another solvent. It reacts with carbon disulfide and sodium hydroxide to give sodium isopropylxanthate, a herbicide and an ore flotation reagent.[21] IPHA 15% reacts with titanium tetrachloride and aluminium metal to give titanium and aluminium isopropoxides, respectively, the former a catalyst, and the latter a chemical reagent.[16] This compound may serve as a chemical reagent in itself, by acting as a dihydrogen donor in transfer hydrogenation. Medical of IPHA 15% Rubbing alcohol, hand sanitizer, and disinfecting pads typically contain a 60–70% solution of IPHA 15% or ethanol in water. Water is required to open up membrane pores of bacteria, which acts as a gateway for IPHA 15%. A 75% v/v solution in water may be used as a hand sanitizer.[22] IPHA 15% is used as a water-drying aid for the prevention of otitis externa, better known as swimmer's ear.[23] Early uses as an anesthetic Although IPHA 15% can be used for anesthesia, its many negative attributes or drawbacks prohibit this use. IPHA 15% can also be used similarly to ether as a solvent[24] or as an anesthetic by inhaling the fumes or orally. Early uses included using the solvent as general anesthetic for small mammals[25] and rodents by scientists and some veterinarians. However, it was soon discontinued, as many complications arose, including respiratory irritation, internal bleeding, and visual and hearing problems. In rare cases, respiratory failure leading to death in animals was observed. Automotive IPHA 15% is a major ingredient in "gas dryer" fuel additives. In significant quantities, water is a problem in fuel tanks, as it separates from gasoline and can freeze in the supply lines at low temperatures. Alcohol does not remove water from gasoline, but the alcohol solubilizes water in gasoline. Once soluble, water does not pose the same risk as insoluble water, as it no longer accumulates in the supply lines and freezes but is consumed with the fuel itself. IPHA 15% is often sold in aerosol cans as a windshield or door lock deicer. IPHA 15% is also used to remove brake fluid traces from hydraulic braking systems, so that the brake fluid (usually DOT 3, DOT 4, or mineral oil) does not contaminate the brake pads and cause poor braking. Mixtures of IPHA 15% and water are also commonly used in homemade windshield washer fluid. Laboratory As a biological specimen preservative, IPHA 15% provides a comparatively non-toxic alternative to formaldehyde and other synthetic preservatives. IPHA 15% solutions of 70–99% are used to preserve specimens. IPHA 15% is often used in DNA extraction. A lab worker adds it to a DNA solution to precipitate the DNA, which then forms a pellet after centrifugation. This is possible because DNA is insoluble in IPHA 15%. Safety of IPHA 15% IPHA 15% vapor is denser than air and is flammable, with a flammability range of between 2 and 12.7% in air. It should be kept away from heat and open flame.[26] Distillation of IPHA 15% over magnesium has been reported to form peroxides, which may explode upon concentration. IPHA 15% is a skin irritant. Wearing protective gloves is recommended. Toxicology of IPHA 15% IPHA 15% and its metabolite, acetone, act as central nervous system (CNS) depressants.[31] Poisoning can occur from ingestion, inhalation, or skin absorption. Symptoms of IPHA 15% poisoning include flushing, headache, dizziness, CNS depression, nausea, vomiting, anesthesia, hypothermia, low blood pressure, shock, respiratory depression, and coma.[31] Overdoses may cause a fruity odor on the breath as a result of its metabolism to acetone.[32] IPHA 15% does not cause an anion gap acidosis but it produces an osmolal gap between the calculated and measured osmolalities of serum, as do the other alcohols.[31] IPHA 15% is oxidized to form acetone by alcohol dehydrogenase in the liver,[31] and has a biological half-life in humans between 2.5 and 8.0 hours.[31] Unlike methanol or ethylene glycol poisoning, the metabolites of IPHA 15% are considerably less toxic, and treatment is largely supportive. Furthermore, there is no indication for the use of fomepizole, an alcohol dehydrogenase inhibitor, unless co-ingestion with methanol or ethylene glycol is suspected. In forensic pathology, people who have died as a result of diabetic ketoacidosis usually have blood concentrations of IPHA 15% of tens of mg/dL, while those by fatal IPHA 15% ingestion usually have blood concentrations of hundreds of mg/dL.

SYNONYMS Avapro;2-Butyl-3-[[ 29-( 1H-tetrazol-5-yl) [1, 19-biphenyl]-4-yl] methyl]1,3- diazaspiro[4,4] non-1-en-4-one; 2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro(4.4)non-1-en-4-one; cas no:138402-11-6

ferricchloride iron (III) chloride iron trichloride iron(3+) trichloride iron(III) chloride trichloroiron CAS Number:7705-08-0

FERRIC SULFATE Iron(III) sulfate Iron persulfate Iron tersulfate Diiron tris(sulphate) Diiron trisulfate Ferric persulfate Ferric tersulfate Iron sesquisulfate Ferric sesquisulfate Iron(3+) sulfate Sulfuric acid, iron(3+) salt (3:2) Coquimbite mineral Iron sulfate (2:3) Iron sulfate (Fe2(SO4)3) Iron(3+) sulfate, (2:3) Ferricsulfate Sulfuric acid, iron(3+) salt Iron-S-hydrate iron(III)sulphate Ferric sulfate (USP) Sulfuric acid,iron salt iron(III) sulfate(VI) CAS: 10028-22-5

IRON SULPHATE; Green Vitriol; Copperas; Melanterite; Ferrous sulfate heptahydrate; Sulfuric acid, iron(2+) salt, heptahydrate; Ferrosulfat (German); cas no: 7782-63-0

Ferrous sulfate monohydrate; Iron sulfate monohydrate; Iron(2+) sulfate monohydrate; dried ferrous sulfate ;ferrous sulfate (dried); iron(II) sulfate monohydrate; Ferrosulfate hydrate cas no:13463-43-9

Iron(II) sulfate heptahydrate ;Ferrous sulfate heptahydrate ;Green Vitriol; Copperas; Melanterite;Ferrous sulfate heptahydrate; Sulfuric acid, iron(2+) salt, heptahydrate; Ferrosulfat (German); cas no: 7782-63-0

Diphosphoric acid iron(III) salt, Ferric pyrophosphate ;pyrophosphoric acid iron(3+) salt (3:4); iron (III) pyrophosphate; iron pyrophosphate ;tetrairon tris(pyrophosphate) cas no: 10058-44-3

Urtica diocia extract ;urtica dioica extract; bichu booti extract; extract of the aerial parts of the nettle, urtica dioica l., urticaceae; nettle wort extract cas no: 84012-40-8

BANANA OIL; ISOAMYL ACETATE, N° CAS : 123-92-2. Nom INCI : ISOAMYL ACETATE. Nom chimique : Isopentyl acetate. N° EINECS/ELINCS : 204-662-3. Noms français : 3-METHYL-1-BUTYL ACETATE; 3-METHYLBUTYL ACETATE; 3-METHYLBUTYL ETHANOATE; ACETATE D'ISOAMYLE; ACETATE D'ISOPENTYLE; ACETATE DE METHYL-3 BUTYLE; ACETIC ACID 3-METHYLBUTYL ESTER ;Acétate d'isoamyle. Noms anglais : ACETIC ACID ISOAMYL ESTER; ACETIC ACID ISOPENTYL ESTER; BANANA OIL; Isoamyl acetate; ISOAMYL ACETIC ESTER; ISOAMYL ETHANOATE ISOPENTYL ACETATE; ISOPENTYL ALCOHOL, ACETATE; Pentyl acetate, all isomers [123-92-2]. Utilisation : L'acétate d'isoamyle a beaucoup d'applications industrielles, notamment : comme saveur artificielle de poire ou de banane dans les aliments, dans les produits pour masquer les odeurs, comme test qualitatif pour les appareils respiratoires (test de l'huile de banane) en tant que solvant pour des vernis et des laques, dans les vernis à ongles, dans les films photographiques

ISOAMYL ALLYLGLYCOLATE, N° CAS : 67634-00-8. Nom INCI : ISOAMYL ALLYLGLYCOLATE. Nom chimique : Acetic Acid, (3-Methylbutoxy), 2-Propenyl Ester, N° EINECS/ELINCS : 266-803-5 Ses fonctions (INCI). Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques

ISOAMYL BUTYRATE, N° CAS : 106-27-4, Nom INCI : ISOAMYL BUTYRATE. Nom chimique : 3-Methylbutyl Butanoate. N° EINECS/ELINCS : 203-380-8. Ses fonctions (INCI). Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques

ISOAMYL CINNAMATE, N° CAS : 7779-65-9. Nom INCI : ISOAMYL CINNAMATE, Nom chimique : 2-Propenoic Acid, 3-Phenyl-, 3-Methylbutyl Ester. N° EINECS/ELINCS : 231-931-2. Ses fonctions (INCI). Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit

ISOAMYL LAURATE, N° CAS : 6309-51-9, Nom INCI : ISOAMYL LAURATE. Nom chimique : Isopentyl laurate. N° EINECS/ELINCS : 228-626-1. Classification : Huile estérifiée. Emollient : Adoucit et assouplit la peau. Agent d'entretien de la peau : Maintient la peau en bon état

Isoamyl Cocoate. ISOAMYL COCOATE is classified as : Emollient; Skin conditioning. Chem/IUPAC Name: Isoamyl Cocoate is the ester of isoamyl alcohol and Coconut Acid. It conforms to the formula: (structure)where RCO- represents the coconut acid radical.A natural emollient ester derived from sugar beets and coconut oil. It's a very light liquid that absorbs quickly into the skin and has a non-oily skin feel. Item Number:170595CAS Number:6309-51-9Mfr: APPEARANCE: COLORLESS TO YELLOWISH LIQUID WITH SLIGHT SPECIFIC ODOR DESCRIPTION: Is a very light emollient that is completely based on natural raw materials. It has a low viscosity, low oiliness and absorbs easily. It is produced by enzymatic catalyis.

ISOAMYL P-METHOXYCINNAMATE, N° CAS : 71617-10-2. Origine(s) : Synthétique. Nom INCI : ISOAMYL P-METHOXYCINNAMATE. Nom chimique : Isopentyl p-methoxycinnamate. N° EINECS/ELINCS : 275-702-5. Ses fonctions (INCI) : Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV. Filtre UV : Permet de filtrer certains rayons UV afin de protéger la peau ou les cheveux des effets nocifs de ces rayons.